Form990-PF

Department of the Treasury
Internal Revenue Service

Return of Private Foundation
or Section 4947(a)(1) Trust Treated as Private Foundation
right arrowDo not enter social security numbers on this form as it may be made public.
right arrowGo to www.irs.gov/Form990PF for instructions and the latest information.
OMB No. 1545-0047
2022
Open to Public Inspection
For calendar year 2022, or tax year beginning 01-01-2022 , and ending 12-31-2022
Name of foundation
CHAN ZUCKERBERG INITIATIVE FOUNDATION
 
Number and street (or P.O. box number if mail is not delivered to street address)314 LYTTON AVE
  Room/suite
City or town, state or province, country, and ZIP or foreign postal code
PALO ALTO, CA94301
A Employer identification number

45-5002209
B Telephone number (see instructions)

(650) 804-7100
C right arrow
G Check all that apply:

D 1. Foreign organizations, check here............. right arrow
2. Foreign organizations meeting the 85%
test, check here and attach computation ... right arrow
E right arrow
H Check type of organization:
F right arrow
I Fair market value of all assets at end
of year (from Part II, col. (c),
line 16)right arrow$5,412,475,782J Accounting method:
 
(Part I, column (d) must be on cash basis.)
Part I Analysis of Revenue and Expenses (The total of amounts in columns (b), (c), and (d) may not necessarily equal the amounts in column (a) (see instructions).) (a) Revenue and
expenses per
books 		(b) Net investment
income 		(c) Adjusted net
income 		(d) Disbursements
for charitable
purposes
(cash basis only)
Revenue 1 Contributions, gifts, grants, etc., received (attach schedule) 10,000,000
2 Check right arrow.............
3 Interest on savings and temporary cash investments      
4 Dividends and interest from securities... 10,335,195 28,293,220  
5a Gross rents............      
b Net rental income or (loss)  
6a Net gain or (loss) from sale of assets not on line 10 -194,491,944
b Gross sales price for all assets on line 6a 2,501,389,678
7 Capital gain net income (from Part IV, line 2)... 0
8 Net short-term capital gain.........  
9 Income modifications...........  
10a Gross sales less returns and allowances  
b Less: Cost of goods sold....  
c Gross profit or (loss) (attach schedule).....    
11 Other income (attach schedule)....... Click to see attachment
List of Attached Documents:
// Content
32,562,159 16,329,000 0
12 Total. Add lines 1 through 11........ -141,594,590 44,622,220 0
Operating and Administrative Expenses 13 Compensation of officers, directors, trustees, etc. 0 0 0 0
14 Other employee salaries and wages...... 36,362,705 0 0 32,119,996
15 Pension plans, employee benefits....... 7,709,416 0 0 10,001,020
16a Legal fees (attach schedule)......... Click to see attachment
List of Attached Documents:
// Content
357,578 0 0 359,741
b Accounting fees (attach schedule)....... Click to see attachment
List of Attached Documents:
// Content
431,059 45,115 0 266,863
c Other professional fees (attach schedule).... Click to see attachment
List of Attached Documents:
// Content
11,188,232 885,730 0 9,598,853
17 Interest...............        
18 Taxes (attach schedule) (see instructions)...        
19 Depreciation (attach schedule) and depletion... 4,661 0 0
20 Occupancy.............. 23,092 0 0 9,455
21 Travel, conferences, and meetings....... 468,330 0 0 463,095
22 Printing and publications..........        
23 Other expenses (attach schedule)....... Click to see attachment
List of Attached Documents:
// Content
3,287,796 37,698,242 0 809,899
24 Total operating and administrative expenses.
Add lines 13 through 23.......... 59,832,869 38,629,087 0 53,628,922
25 Contributions, gifts, grants paid....... 342,805,084 364,708,682
26 Total expenses and disbursements. Add lines 24 and 25 402,637,953 38,629,087 0 418,337,604
27 Subtract line 26 from line 12:
a Excess of revenue over expenses and disbursements -544,232,543
b Net investment income (if negative, enter -0-) 5,993,133
c Adjusted net income (if negative, enter -0-)... 0
For Paperwork Reduction Act Notice, see instructions.
Cat. No. 11289X Form 990-PF (2022)
Page 2
Form 990-PF (2022)
Page 2
Part II Balance Sheets Attached schedules and amounts in the description column
should be for end-of-year amounts only. (See instructions.) 		Beginning of year End of year
(a) Book Value (b) Book Value (c) Fair Market Value
Assets 1 Cash—non-interest-bearing............. 5,163,078 6,116,121 6,116,121
2 Savings and temporary cash investments......... 388,320,684 676,574,775 676,574,775
3 Accounts receivable right arrow2,035,911
Less: allowance for doubtful accounts right arrow   1,160,343 2,035,911 2,035,911
4 Pledges receivable right arrow  
Less: allowance for doubtful accounts right arrow        
5 Grants receivable.................      
6 Receivables due from officers, directors, trustees, and other
disqualified persons (attach schedule) (see instructions).....      
7 Other notes and loans receivable (attach schedule) right arrow  
Less: allowance for doubtful accounts right arrow        
8 Inventories for sale or use..............      
9 Prepaid expenses and deferred charges.......... 274,786 2,253,065 2,253,065
10a Investments—U.S. and state government obligations (attach schedule) 398,286,206 Click to see attachment
List of Attached Documents:
// Content
127,593,573 		127,593,573
b Investments—corporate stock (attach schedule)....... 874,395,278 Click to see attachment
List of Attached Documents:
// Content
386,801,299 		386,801,299
c Investments—corporate bonds (attach schedule).......      
11 Investments—land, buildings, and equipment: basis right arrow  
Less: accumulated depreciation (attach schedule) right arrow        
12 Investments—mortgage loans.............      
13 Investments—other (attach schedule).......... 5,397,157,139 Click to see attachment
List of Attached Documents:
// Content
4,175,143,872 		4,175,143,872
14 Land, buildings, and equipment: basis right arrow39,950
Less: accumulated depreciation (attach schedule) right arrow4,661 0 35,289 35,289
15 Other assets (describe right arrow) Click to see attachment
List of Attached Documents:
// Content
37,618,247 		Click to see attachment
List of Attached Documents:
// Content
35,921,877 		Click to see attachment
List of Attached Documents:
// Content
35,921,877
16 Total assets (to be completed by all filers—see the
instructions. Also, see page 1, item I) 7,102,375,761 5,412,475,782 5,412,475,782
Liabilities 17 Accounts payable and accrued expenses.......... 5,940,681 8,742,589
18 Grants payable................. 617,337,895 595,346,765
19 Deferred revenue.................    
20 Loans from officers, directors, trustees, and other disqualified persons    
21 Mortgages and other notes payable (attach schedule)......    
22 Other liabilities (describe right arrow) Click to see attachment
List of Attached Documents:
// Content
26,000,000 		Click to see attachment
List of Attached Documents:
// Content
75,113,614
23 Total liabilities (add lines 17 through 22)......... 649,278,576 679,202,968
Net Assets or Fund Balances Foundations that follow FASB ASC 958, check here right arrow
and complete lines 24, 25, 29 and 30.
24 Net assets without donor restrictions........... 6,453,097,185 4,733,272,814
25 Net assets with donor restrictions............    
Foundations that do not follow FASB ASC 958, check here right arrow
and complete lines 26 through 30.
26 Capital stock, trust principal, or current funds........    
27 Paid-in or capital surplus, or land, bldg., and equipment fund    
28 Retained earnings, accumulated income, endowment, or other funds    
29 Total net assets or fund balances (see instructions)..... 6,453,097,185 4,733,272,814
30 Total liabilities and net assets/fund balances (see instructions). 7,102,375,761 5,412,475,782
Part III
Analysis of Changes in Net Assets or Fund Balances
1
Total net assets or fund balances at beginning of year—Part II, column (a), line 29 (must agree with end-of-year figure reported on prior year’s return) ...............
1
6,453,097,185
2
Enter amount from Part I, line 27a .....................
2
-544,232,543
3
Other increases not included in line 2 (itemize) right arrow
3
0
4
Add lines 1, 2, and 3 ..........................
4
5,908,864,642
5
Decreases not included in line 2 (itemize) right arrowClick to see attachment
List of Attached Documents:
// Content
5
1,175,591,828
6
Total net assets or fund balances at end of year (line 4 minus line 5)—Part II, column (b), line 29 .
6
4,733,272,814
Form 990-PF (2022)
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Form 990-PF (2022)
Page 3
Part IV
Capital Gains and Losses for Tax on Investment Income
(a) List and describe the kind(s) of property sold (e.g., real estate,
2-story brick warehouse; or common stock, 200 shs. MLC Co.)		 (b)
How acquired
P—Purchase
D—Donation 		(c)
Date acquired
(mo., day, yr.) 		(d)
Date sold
(mo., day, yr.)
1 a PUBLICLY TRADED SECURITIES   2020-12-31 2022-12-31
b ALTERNATIVE INVESTMENTS P 2019-12-31 2022-12-31
c
d
e
(e)
Gross sales price 		(f)
Depreciation allowed
(or allowable) 		(g)
Cost or other basis
plus expense of sale 		(h)
Gain or (loss)
(e) plus (f) minus (g)
a 1,066,622,674   1,062,258,066 4,364,608
b 1,434,767,004   1,598,297,955 -163,530,951
c
d
e
Complete only for assets showing gain in column (h) and owned by the foundation on 12/31/69 (l)
Gains (Col. (h) gain minus
col. (k), but not less than -0-) or
Losses (from col.(h))
(i)
F.M.V. as of 12/31/69 		(j)
Adjusted basis
as of 12/31/69 		(k)
Excess of col. (i)
over col. (j), if any
a       4,364,608
b       -163,530,951
c
d
e
2 Capital gain net income or (net capital loss) Bracket If gain, also enter in Part I, line 7
If (loss), enter -0- in Part I, line 7		 Bracket 2 -159,166,343
3 Net short-term capital gain or (loss) as defined in sections 1222(5) and (6):
If gain, also enter in Part I, line 8, column (c) (see instructions). If (loss), enter -0-
in Part I, line 8 ................... 		Bracket 3 0
Form 990-PF (2022)
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Form 990-PF (2022)
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Part V
Excise Tax Based on Investment Income (Section 4940(a), 4940(b), 4940(e), or 4948—see instructions)
1a Exempt operating foundations described in section 4940(d)(2), check here right arrow and enter “N/A" on line 1. Bracket for line 1a
Date of ruling or determination letter:   (attach copy of letter if necessary–see instructions) 1 83,305
b All other domestic foundations enter 1.39% (0.0139) of line 27b. Exempt foreign organizations enter 4% (0.04) of Part I, line 12, col. (b)
2 Tax under section 511 (domestic section 4947(a)(1) trusts and taxable foundations only. Others enter -0-) 2 0
3 Add lines 1 and 2........................... 3 83,305
4 Subtitle A (income) tax (domestic section 4947(a)(1) trusts and taxable foundations only. Others enter -0-) 4 0
5 Tax based on investment income. Subtract line 4 from line 3. If zero or less, enter -0- ..... 5 83,305
6 Credits/Payments:
a 2022 estimated tax payments and 2021 overpayment credited to 2022 6a 2,690,626
b Exempt foreign organizations—tax withheld at source...... 6b 0
c Tax paid with application for extension of time to file (Form 8868)... 6c 0
d Backup withholding erroneously withheld .......... 6d 0
7 Total credits and payments. Add lines 6a through 6d.............. 7 2,690,626
8 Enter any penalty for underpayment of estimated tax. Check here if Form 2221 is attached. Click to see attachment
List of Attached Documents:
// Content
8 0
9 Tax due. If the total of lines 5 and 8 is more than line 7, enter amount owed.......right arrow 9  
10 Overpayment. If line 7 is more than the total of lines 5 and 8, enter the amount overpaid...right arrow 10 2,607,321
11 Enter the amount of line 10 to be: Credited to 2023 estimated taxright arrow2,607,321 Refundedright arrow 11 0
Part VI-A
Statements Regarding Activities
1a
During the tax year, did the foundation attempt to influence any national, state, or local legislation or did
Yes
No
it participate or intervene in any political campaign? ....................
1a
 
No
b
Did it spend more than $100 during the year (either directly or indirectly) for political purposes? See the instructions
for the definition.................................
1b
 
No
If the answer is "Yes" to 1a or 1b, attach a detailed description of the activities and copies of any materials
published or distributed by the foundation in connection with the activities.
c
Did the foundation file Form 1120-POL for this year?.....................
1c
 
No
d
Enter the amount (if any) of tax on political expenditures (section 4955) imposed during the year:
(1) On the foundation. right arrow$ 0(2) On foundation managers.right arrow$ 0
e
Enter the reimbursement (if any) paid by the foundation during the year for political expenditure tax imposed
on foundation managers.right arrow$ 0
2
Has the foundation engaged in any activities that have not previously been reported to the IRS?.......
2
 
No
If "Yes," attach a detailed description of the activities.
3
Has the foundation made any changes, not previously reported to the IRS, in its governing instrument, articles
of incorporation, or bylaws, or other similar instruments? If "Yes," attach a conformed copy of the changes....
3
 
No
4a
Did the foundation have unrelated business gross income of $1,000 or more during the year?.........
4a
Yes
 
b
If "Yes," has it filed a tax return on Form 990-T for this year?...................
4b
Yes
 
5
Was there a liquidation, termination, dissolution, or substantial contraction during the year?.........
5
 
No
If "Yes," attach the statement required by General Instruction T.
6
Are the requirements of section 508(e) (relating to sections 4941 through 4945) satisfied either:
round bullet By language in the governing instrument, or
round bullet By state legislation that effectively amends the governing instrument so that no mandatory directions
that conflict with the state law remain in the governing instrument? ................
6
Yes
 
7
Did the foundation have at least $5,000 in assets at any time during the year? If "Yes," complete Part II, col. (c),
and Part XIV..................................
7
Yes
 
8a
Enter the states to which the foundation reports or with which it is registered (see instructions)
right arrowCA
b
If the answer is "Yes" to line 7, has the foundation furnished a copy of Form 990-PF to the Attorney
General (or designate) of each state as required by General Instruction G? If "No," attach explanation .
8b
Yes
 
9
Is the foundation claiming status as a private operating foundation within the meaning of section 4942(j)(3)
or 4942(j)(5) for calendar year 2022 or the taxable year beginning in 2022? See the instructions for Part XIII.
If "Yes," complete Part XIII .............................
9
 
No
10
Did any persons become substantial contributors during the tax year? If "Yes," attach a schedule listing their names
and addresses. ...............................
10
 
No
Form 990-PF (2022)
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Form 990-PF (2022)
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Part VI-A
Statements Regarding Activities (continued)
11
At any time during the year, did the foundation, directly or indirectly, own a controlled entity within the
meaning of section 512(b)(13)? If "Yes," attach schedule. See instructions Click to see attachment
List of Attached Documents:
// Content
.............
11
Yes
 
12
Did the foundation make a distribution to a donor advised fund over which the foundation or a disqualified person had
advisory privileges? If "Yes," attach statement. See instructionsClick to see attachment
List of Attached Documents:
// Content
.................
12
Yes
 
13
Did the foundation comply with the public inspection requirements for its annual returns and exemption application?
13
Yes
 
Website addressright arrowN/A
14
The books are in care ofright arrowTHE FOUNDATION Telephone no.right arrow (650) 804-7100

Located atright arrow314 LYTTON AVEPALO ALTOCA ZIP+4right arrow94301
15
Section 4947(a)(1) nonexempt charitable trusts filing Form 990-PF in lieu of Form 1041 —check here .........right arrow
and enter the amount of tax-exempt interest received or accrued during the year ........right arrow
15
 
16 At any time during calendar year 2022, did the foundation have an interest in or a signature or other authority over YesNo
a bank, securities, or other financial account in a foreign country? .................
16   No
See the instructions for exceptions and filing requirements for FinCEN Form 114. If "Yes", enter the name of the foreign
country right arrow
Part VI-B
Statements Regarding Activities for Which Form 4720 May Be Required
File Form 4720 if any item is checked in the "Yes" column, unless an exception applies.
Yes
No
1a
During the year did the foundation (either directly or indirectly):
(1) Engage in the sale or exchange, or leasing of property with a disqualified person? ...........
1a(1)
 
No
(2) Borrow money from, lend money to, or otherwise extend credit to (or accept it from)
a disqualified person? ..............................
1a(2)
 
No
(3) Furnish goods, services, or facilities to (or accept them from) a disqualified person? ...........
1a(3)
Yes
 
(4) Pay compensation to, or pay or reimburse the expenses of, a disqualified person? ............
1a(4)
 
No
(5) Transfer any income or assets to a disqualified person (or make any of either available
for the benefit or use of a disqualified person)? ......................
1a(5)
 
No
(6) Agree to pay money or property to a government official? (Exception. Check "No"
if the foundation agreed to make a grant to or to employ the official for a period
after termination of government service, if terminating within 90 days.) ...............
1a(6)
 
No
b
If any answer is "Yes" to 1a(1)–(6), did any of the acts fail to qualify under the exceptions described in Regulations
section 53.4941(d)-3 or in a current notice regarding disaster assistance? See instructions ..........
1b
 
No
c
Organizations relying on a current notice regarding disaster assistance check here ........right arrow
d
Did the foundation engage in a prior year in any of the acts described in 1a, other than excepted acts,
that were not corrected before the first day of the tax year beginning in 2022? .............
1d
 
No
2
Taxes on failure to distribute income (section 4942) (does not apply for years the foundation was a private
operating foundation defined in section 4942(j)(3) or 4942(j)(5)):
a
At the end of tax year 2022, did the foundation have any undistributed income (Part XII, lines 6d
and 6e) for tax year(s) beginning before 2022?....................
2a
 
No
If "Yes," list the years right arrow20, 20, 20, 20
b
Are there any years listed in 2a for which the foundation is not applying the provisions of section 4942(a)(2)
(relating to incorrect valuation of assets) to the year’s undistributed income? (If applying section 4942(a)(2)
to all years listed, answer "No" and attach statement—see instructions.) ..............
2b
 
 
c
If the provisions of section 4942(a)(2) are being applied to any of the years listed in 2a, list the years here.
right arrow20, 20, 20, 20
3a
Did the foundation hold more than a 2% direct or indirect interest in any business enterprise at
any time during the year? ..............................
3a
Yes
 
b
If "Yes," did it have excess business holdings in 2022 as a result of (1) any purchase by the foundation
or disqualified persons after May 26, 1969; (2) the lapse of the 5-year period (or longer period approved
by the Commissioner under section 4943(c)(7)) to dispose of holdings acquired by gift or bequest; or (3)
the lapse of the 10-, 15-, or 20-year first phase holding period? (Use Schedule C, Form 4720, to determine
if the foundation had excess business holdings in 2022.) .....................
3b
 
No
4a
Did the foundation invest during the year any amount in a manner that would jeopardize its charitable purposes?
4a
 
No
b
Did the foundation make any investment in a prior year (but after December 31, 1969) that could jeopardize its
charitable purpose that had not been removed from jeopardy before the first day of the tax year beginning in 2022? ..
4b
 
No
Form 990-PF (2022)
Page 6
Form 990-PF (2022)
Page 6
Part VI-B
Statements Regarding Activities for Which Form 4720 May Be Required (continued)
5a
During the year did the foundation pay or incur any amount to:
Yes
No
(1) Carry on propaganda, or otherwise attempt to influence legislation (section 4945(e))? ..........
5a(1)
 
No
(2) Influence the outcome of any specific public election (see section 4955); or to carry
on, directly or indirectly, any voter registration drive? ....................
5a(2)
 
No
(3) Provide a grant to an individual for travel, study, or other similar purposes? .............
5a(3)
 
No
(4) Provide a grant to an organization other than a charitable, etc., organization described
in section 4945(d)(4)(A)? See instructions ........................
5a(4)
Yes
 
(5) Provide for any purpose other than religious, charitable, scientific, literary, or
educational purposes, or for the prevention of cruelty to children or animals? .............
5a(5)
 
No
b
If any answer is "Yes" to 5a(1)–(5), did any of the transactions fail to qualify under the exceptions described in
Regulations section 53.4945 or in a current notice regarding disaster assistance? See instructions ........
5b
 
No
c
Organizations relying on a current notice regarding disaster assistance check .........right arrow
d
If the answer is "Yes" to question 5a(4), does the foundation claim exemption from the
tax because it maintained expenditure responsibility for the grant? .................
5d
Yes
 
If "Yes," attach the statement required by Regulations section 53.4945–5(d). Click to see attachment
List of Attached Documents:
// Content
6a
Did the foundation, during the year, receive any funds, directly or indirectly, to pay premiums on
a personal benefit contract? .............................
6a
 
No
b
Did the foundation, during the year, pay premiums, directly or indirectly, on a personal benefit contract? ....
6b
 
No
If "Yes" to 6b, file Form 8870.
7a
At any time during the tax year, was the foundation a party to a prohibited tax shelter transaction?
7a
 
No
b
If "Yes", did the foundation receive any proceeds or have any net income attributable to the transaction? .....
7b
 
 
8
Is the foundation subject to the section 4960 tax on payment(s) of more than $1,000,000 in remuneration or
excess parachute payment during the year? .........................
8
 
No
Part VII
Information About Officers, Directors, Trustees, Foundation Managers, Highly Paid Employees,
and Contractors
1 List all officers, directors, trustees, foundation managers and their compensation. See instructions
(a) Name and address (b) Title, and average
hours per week
devoted to position 		(c) Compensation
 (If not paid, enter
-0-) 		(d) Contributions to employee benefit plans and deferred compensation (e) Expense account,
other allowances
MARK ZUCKERBERG TRUSTEE
1.00 		0 0 0
314 LYTTON AVE
PALO ALTO,CA94301
BRIAN MANCA FINANCE OFFICER
1.00 		0 0 0
314 LYTTON AVE
PALO ALTO,CA94301
2 Compensation of five highest-paid employees (other than those included on line 1—see instructions). If none, enter “NONE."
(a) Name and address of each employee paid more than $50,000 (b) Title, and average
hours per week
devoted to position 		(c) Compensation (d) Contributions to
employee benefit
plans and deferred
compensation 		(e) Expense account,
other allowances
ROBERT BROWN DIRECTOR, ENGINEERIN
40.00 		653,002 35,396 0
314 LYTTON AVE
PALO ALTO,CA94301
STEPHANI OTTE SCIENCE PROGRAM OFFI
40.00 		637,968 34,233 0
314 LYTTON AVE
PALO ALTO,CA94301
PATRICIA BRENNAN VICE PRESIDENT, PROD
40.00 		628,570 41,858 0
314 LYTTON AVE
PALO ALTO,CA94301
TANIA SIMONCELLI VICE PRESIDENT, SCIE
40.00 		570,328 37,473 0
314 LYTTON AVE
PALO ALTO,CA94301
KATJA BROSE SENIOR SCIENCE PROGR
40.00 		545,104 34,378 0
314 LYTTON AVE
PALO ALTO,CA94301
Total number of other employees paid over $50,000...................right arrow 135
Form 990-PF (2022)
Page 7
Form 990-PF (2022)
Page 7
Part VII
Information About Officers, Directors, Trustees, Foundation Managers, Highly Paid Employees,
and Contractors (continued)
3 Five highest-paid independent contractors for professional services (see instructions). If none, enter "NONE".
(a) Name and address of each person paid more than $50,000 (b) Type of service (c) Compensation
DELOITTE INC SOFTWARE DEVELOPMENT 2,977,702
8 ADELAIDE ST WEST STE 200
TORONTO,ONTARIOM5H0A9
CA
QUANSIGHT LLC SOFTWARE DEVELOPMENT 919,176
8656 W HIGHWAY 71 BLDG F200
AUSTIN,TX78735
APEX SYSTEMS LLC CONTRACTOR 817,568
4400 COX ROAD STE 200
GLEN ALLEN,VA23060
ICONIQ CAPITAL LLC TREASURY SERVICES FEE 750,000
50 BEALE ST STE 2300
SAN FRANCISCO,CA94105
TALENTBURST INC CONTRACTOR 534,829
679 WORCESTER ST
NATICK,MA01760
Total number of others receiving over $50,000 for professional services.............right arrow37
Part VIII-A
Summary of Direct Charitable Activities
List the foundation’s four largest direct charitable activities during the tax year. Include relevant statistical information such as the number of organizations and other beneficiaries served, conferences convened, research papers produced, etc. Expenses
1 TO CURE, PREVENT, OR MANAGE ALL DISEASE BY THE END OF THE CENTURY, FOUNDATION PERSONNEL BUILD AND SUPPORT A VARIETY OF TRANSFORMATIVE TECHNOLOGIES IN PARTNERSHIP WITH THE SCIENTIFIC COMMUNITY AND FOSTER INTERDISCIPLINARY RESEARCH COLLABORATIONS. MAJOR AREAS OF THIS WORK INCLUDE IMAGING TECHNOLOGIES CAPABLE OF BETTER OBSERVING BIOLOGICAL PROCESSES; SINGLE-CELL TECHNOLOGIES TO ENABLE SCIENTISTS TO BETTER AND MORE QUICKLY UNDERSTAND HOW DISEASES MANIFEST IN THE BODY; OPEN SOURCE PLATFORMS THAT ACCELERATE THE DETECTION, IDENTIFICATION, AND TRACKING OF INFECTIOUS DISEASE; AND A RESEARCH DISCOVERY TOOL POWERED BY MACHINE LEARNING. 53,628,922
2  
3  
4  
Part VIII-B
Summary of Program-Related Investments (see instructions)
Describe the two largest program-related investments made by the foundation during the tax year on lines 1 and 2. Amount
1 LOAN TO SUPPORT INFILL DEVELOPMENT AND HOMEOWNERSHIP DEMONSTRATION PILOTS IN LOS ANGELES COUNTY, IN PARTNERSHIP WITH A LOCAL NON-BANK FINANCING INSTITUTION, COMMUNITY-BASED ORGANIZATIONS, AND NONPROFIT DEVELOPERS. 2,000,000
2  
All other program-related investments. See instructions.
3  
Total. Add lines 1 through 3.........................right arrow2,000,000
Form 990-PF (2022)
Page 8
Form 990-PF (2022)
Page 8
Part IX
Minimum Investment Return (All domestic foundations must complete this part. Foreign foundations, see instructions.)
1
Fair market value of assets not used (or held for use) directly in carrying out charitable, etc.,
purposes:
a
Average monthly fair market value of securities...................
1a
1,339,047,499
b
Average of monthly cash balances.......................
1b
500,952,986
c
Fair market value of all other assets (see instructions)................
1c
4,156,372,193
d
Total (add lines 1a, b, and c).........................
1d
5,996,372,678
e
Reduction claimed for blockage or other factors reported on lines 1a and
1c (attach detailed explanation) .............
1e
0
2
Acquisition indebtedness applicable to line 1 assets..................
2
0
3
Subtract line 2 from line 1d.........................
3
5,996,372,678
4
Cash deemed held for charitable activities. Enter 1.5% (0.015) of line 3 (for greater amount, see
instructions) .............................
4
89,945,590
5
Net value of noncharitable-use assets. Subtract line 4 from line 3. ............
5
5,906,427,088
6
Minimum investment return. Enter 5% (0.05) of line 5................
6
295,321,354
Part X
Distributable Amount (see instructions) (Section 4942(j)(3) and (j)(5) private operating foundations and certain foreign organizations check here right arrow and do not complete this part.)
1
Minimum investment return from Part IX, line 6..................
1
295,321,354
2a
Tax on investment income for 2022 from Part V, line 5.......
2a
83,305
b
Income tax for 2022. (This does not include the tax from Part V.) ...
2b
 
c
Add lines 2a and 2b............................
2c
83,305
3
Distributable amount before adjustments. Subtract line 2c from line 1............
3
295,238,049
4
Recoveries of amounts treated as qualifying distributions................
4
297,275
5
Add lines 3 and 4............................
5
295,535,324
6
Deduction from distributable amount (see instructions).................
6
0
7
Distributable amount as adjusted. Subtract line 6 from line 5. Enter here and on Part XII, line 1 ...
7
295,535,324
Part XI
Qualifying Distributions (see instructions)
1
Amounts paid (including administrative expenses) to accomplish charitable, etc., purposes:
a
Expenses, contributions, gifts, etc.—total from Part I, column (d), line 26 ..........
1a
418,337,604
b
Program-related investments—total from Part VIII-B..................
1b
2,000,000
2
Amounts paid to acquire assets used (or held for use) directly in carrying out charitable, etc.,
purposes...............................
2
39,950
3
Amounts set aside for specific charitable projects that satisfy the:
a
Suitability test (prior IRS approval required)....................
3a
 
b
Cash distribution test (attach the required schedule) .................
3b
 
4
Qualifying distributions. Add lines 1a through 3b. Enter here and on Part XII, line 4. .......
4
420,377,554
Form 990-PF (2022)
Page 9
Form 990-PF (2022)
Page 9
Part XII
Undistributed Income (see instructions)
(a)
Corpus 		(b)
Years prior to 2021 		(c)
2021 		(d)
2022
1 Distributable amount for 2022 from Part X, line 7 295,535,324
2 Undistributed income, if any, as of the end of 2022:
a Enter amount for 2021 only....... 255,438,880
b Total for prior years:20, 20, 20 0
3 Excess distributions carryover, if any, to 2022:
a From 2017......  
b From 2018......  
c From 2019......  
d From 2020......  
e From 2021......  
f Total of lines 3a through e ........ 0
4Qualifying distributions for 2022 from Part
XI, line 4: right arrow$ 420,377,554
a Applied to 2021, but not more than line 2a 255,438,880
b Applied to undistributed income of prior years
(Election required—see instructions)..... 		0
c Treated as distributions out of corpus (Election
required—see instructions)........ 		0
d Applied to 2022 distributable amount..... 164,938,674
e Remaining amount distributed out of corpus 0
5 Excess distributions carryover applied to 2022. 0 0
(If an amount appears in column (d), the
same amount must be shown in column (a).)
6Enter the net total of each column as
indicated below:
a Corpus. Add lines 3f, 4c, and 4e. Subtract line 5 0
b Prior years’ undistributed income. Subtract
line 4b from line 2b .......... 		0
c Enter the amount of prior years’ undistributed
income for which a notice of deficiency has
been issued, or on which the section 4942(a)
tax has been previously assessed...... 		0
d Subtract line 6c from line 6b. Taxable amount
—see instructions ........... 		0
e Undistributed income for 2021. Subtract line
4a from line 2a. Taxable amount—see
instructions ............. 		0
f Undistributed income for 2022. Subtract
lines 4d and 5 from line 1. This amount must
be distributed in 2023 .......... 		130,596,650
7 Amounts treated as distributions out of
corpus to satisfy requirements imposed by
section 170(b)(1)(F) or 4942(g)(3) (Election may
be required - see instructions) ....... 		0
8 Excess distributions carryover from 2017 not
applied on line 5 or line 7 (see instructions) ... 		0
9 Excess distributions carryover to 2023.
Subtract lines 7 and 8 from line 6a ...... 		0
10 Analysis of line 9:
a Excess from 2018....  
b Excess from 2019....  
c Excess from 2020....  
d Excess from 2021....  
e Excess from 2022....  
Form 990-PF (2022)
Page 10
Form 990-PF (2022)
Page 10
Part XIII
Private Operating Foundations (see instructions and Part VI-A, question 9)
1a If the foundation has received a ruling or determination letter that it is a private operating
foundation, and the ruling is effective for 2022, enter the date of the ruling ...... right arrow
 
b Check box to indicate whether the organization is a private operating foundation described in section or
2a Enter the lesser of the adjusted net
income from Part I or the minimum
investment return from Part IX for each
year listed .......... 		Tax year Prior 3 years (e) Total
(a) 2022 (b) 2021 (c) 2020 (d) 2019
         
b 85% (0.85) of line 2a .........          
c Qualifying distributions from Part XI,
line 4 for each year listed ..... 		         
d Amounts included in line 2c not used directly
for active conduct of exempt activities .......... 		         
e Qualifying distributions made directly
for active conduct of exempt activities.
Subtract line 2d from line 2c .... 		         
3 Complete 3a, b, or c for the
alternative test relied upon:
a “Assets" alternative test—enter:
(1) Value of all assets ......          
(2) Value of assets qualifying
under section 4942(j)(3)(B)(i)		          
b “Endowment" alternative test— enter 2/3
of minimum investment return shown in
Part IX, line 6 for each year listed .. 		         
c “Support" alternative test—enter:
(1) Total support other than gross
investment income (interest,
dividends, rents, payments
on securities loans (section
512(a)(5)), or royalties) .... 		         
(2) Support from general public
and 5 or more exempt
organizations as provided in
section 4942(j)(3)(B)(iii).... 		         
(3) Largest amount of support
from an exempt organization		          
(4) Gross investment income          
Part XIV
Supplementary Information (Complete this part only if the foundation had $5,000 or more in
assets at any time during the year—see instructions.)
1Information Regarding Foundation Managers:
aList any managers of the foundation who have contributed more than 2% of the total contributions received by the foundation
before the close of any tax year (but only if they have contributed more than $5,000). (See section 507(d)(2).)
MARK ZUCKERBERG
bList any managers of the foundation who own 10% or more of the stock of a corporation (or an equally large portion of the
ownership of a partnership or other entity) of which the foundation has a 10% or greater interest.
2Information Regarding Contribution, Grant, Gift, Loan, Scholarship, etc., Programs:
Check here right arrow
aThe name, address, and telephone number or email address of the person to whom applications should be addressed:
bThe form in which applications should be submitted and information and materials they should include:
cAny submission deadlines:
dAny restrictions or limitations on awards, such as by geographical areas, charitable fields, kinds of institutions, or other
factors:
Form 990-PF (2022)
Page 11
Form 990-PF (2022)
Page 11
Part XIV
Supplementary Information (continued)
3 Grants and Contributions Paid During the Year or Approved for Future Payment
Recipient If recipient is an individual,
show any relationship to
any foundation manager
or substantial contributor
 Foundation
status of
recipient 		Purpose of grant or
contribution 		Amount
Name and address (home or business)
aPaid during the year

ACTIVATE GLOBAL INC

2150 SHATTUCK AVE STE 300
BERKELEY,CA94704 		  PC CARBON DIOXIDE REMOVAL INNOVATIONS 769,674

BARR CENTER

PO BOX 249 2355 FAIRVIEW AVE
ROSEVILLE,MN55430 		  PC IMPROVE PROCUREMENT FOR EVIDENCE-BASED PRACTICES THAT SUPPORT TEACHER AND STUDENT RELATIONSHIPS IN SCHOOLS 500,000

BELOVED COMMUNITY

1700 S RAMPART ST
NEW ORLEANS,LA70113 		  PC DEVELOP EQUITY ASSESSMENT PLATFORM; SUPPORT AN INAUGURAL CONVENING 1,850,000

BLUE GRASS COMMUNITY FOUNDATION INC

499 E HIGH ST
LEXINGTON,KY40507 		  PC SUPPORT THE KENTUCKY STUDENT VOICE TEAM 100,000

BROAD INSTITUTE INC

415 MAIN ST
CAMBRIDGE,MA02139 		  PC HUMAN CELL ATLAS DATA ECOSYSTEM 1,256,250

CAJON VALLEY UNION SCHOOL DISTRICT

750 E MAIN ST
EL CAJON,CA92020 		  GOV DEVELOP ASSESSMENTS AND INTEROPERABLE DATA VISUALIZATION TOOLS 500,000

CALIFORNIANS FOR JUSTICE EDUCATION FUND INC

1971 LAS PLUMAS AVE
SAN JOSE,CA95133 		  PC GENERAL OPERATING SUPPORT 750,000

CARBON180

1140 3RD ST NE
WASHINGTON,DC20002 		  PC GENERAL OPERATING SUPPORT 1,333,333

CENTER FOR DEMOCRACY AND TECHNOLOGY

1401 K ST NW
WASHINGTON,DC20005 		  PC GENERAL OPERATING SUPPORT 1,000,000

CHAN ZUCKERBERG BIOHUB INC

499 ILLINOIS ST 4TH FLOOR
SAN FRANCISCO,CA94158 		  PC MEDICAL RESEARCH 85,000,000

CHAN ZUCKERBERG BIOHUB INC

499 ILLINOIS ST 4TH FLOOR
SAN FRANCISCO,CA94158 		  PC ESTABLISHMENT OF THE CHAN ZUCKERBERG BIOHUB NETWORK 5,000,000

CHARLES DREW UNIVERSITY OF SCIENCE & MEDICINE

1731 EAST 120TH ST
LOS ANGELES,CA90059 		  PC ACCELERATE GENOMICS RESEARCH AND PRECISION HEALTH FOR EVERYONE 2,300,000

CHILD TRENDS INC

7315 WISCONSIN AVE 1200
BETHESDA,MD20814 		  PC EVALUATION FOR AND IMPLEMENTATION OF STRONG LOGIC MODELS TO GENERATE EVIDENCE ALIGNED TO ESSA TIER 3 679,000

CLIMATEWORKS FOUNDATION

235 MONTGOMERY ST STE 1300
SAN FRANCISCO,CA94104 		  PC CARBON DIOXIDE REMOVAL PROGRAM 2,500,000

COALITION OF SCHOOLS EDUCATING BOYS OF COLOR INC

255 MAIN ST
CAMBRIDGE,MA02142 		  PC GENERAL OPERATING SUPPORT 650,000

COLD SPRING HARBOR LABORATORY

1 BUNGTOWN RD
COLD SPRING HARBOR,NY11724 		  PC IMPROVE THE SUSTAINABILITY AND CAPACITY OF BIORXIV/MEDRXIV 2,900,000

CURII CORPORATION

212 ELM ST 3RD FLOOR
SOMERVILLE,MA02144 		  NC OPEN SCIENCE 199,988

DATA QUALITY CAMPAIGN

1341 G ST NW STE 700
WASHINGTON,DC20005 		  PC GENERAL OPERATING SUPPORT 600,000

EDUCATION LEADERS OF COLOR INC

3680 WILSHIRE BLVD STE P-04-1052
LOS ANGELES,CA90010 		  PC GENERAL OPERATING SUPPORT 1,000,000

EDUCATION TRUST INC

1501 K ST NW STE 200
WASHINGTON,DC20005 		  PC GENERAL OPERATING SUPPORT 750,000

EDUCATION TRAINING AND RESEARCH ASSOCIATES

5619 SCOTTS VALLEY DR
SCOTT VALLEY,CA95063 		  PC SUPPORT DISTRICT AND RESEARCH PARTNERSHIPS TO IMPLEMENT WHOLE CHILD PRACTICES 370,000

EDUCATIONSUPERHIGHWAY

101 CALIFORNIA ST
SAN FRANCISCO,CA94111 		  PC GENERAL OPERATING SUPPORT 1,000,000

EMPOWERED FAMILIES INC

1630 N MERIDIAN ST STE 450
INDIANAPOLIS,IN46202 		  PC GENERAL OPERATING SUPPORT 200,000

ENTERPRISE COMMUNITY PARTNERS INC

70 CORPORATE CENTER
COLUMBIA,MD21044 		  PC LOCAL RENTAL OWNER COOPERATIVE PILOT IN SOUTH LOS ANGELES 320,000

EQUAL OPPORTUNITY SCHOOLS

130 NICKERSON ST STE 200
SEATTLE,WA98109 		  PC MULTI-YEAR REDESIGN OF THE ACTION FOR EQUITY (A4E) SURVEY AND STUDENT INSIGHT CARD 400,000

EUROPEAN MOLECULAR BIOLOGY LABORATORY

MEYERHOFSTRASSE 1
HEIDELBERG   69117
GM 		  PC HUMAN CELL ATLAS DATA ECOSYSTEM 1,024,716

FAITHACTS FOR EDUCATION

160 FAIRFIELD AVE STE 310
BRIDGEPORT,CT06604 		  PC GENERAL OPERATING SUPPORT 750,000

FELLOWSHIP FOR RACE & EQUITY IN EDUCATION

4828 ILLINOIS AVE NW
WASHINGTON,DC20011 		  PC GENERAL OPERATING SUPPORT 500,000

FLOURISH AGENDA

1714 FRANKLIN ST STE 100-321
OAKLAND,CA94612 		  PC CULTURALLY BASED HEALING STRATEGIES 750,000

FPF EDUCATION AND INNOVATION FOUNDATION

1350 I ST NW STE 350
WASHINGTON,DC20005 		  PC GENERAL OPERATING SUPPORT 1,000,000

FRAMEWORKS INSTITUTE

1333 H ST NW
WASHINGTON,DC20005 		  PC FRAMING AND NARRATIVE STRATEGY DEVELOPMENT FOR ORGANIZATIONAL COMMUNICATIONS 299,000

FRESNO BARRIOS UNIDOS

4403 E TULARE AVE
FRESNO,CA93702 		  PC GENERAL OPERATING SUPPORT 750,000

FWDUS EDUCATION FUND INC

1776 MASSACHUSETTS AVE STE 601
WASHINGTON,DC20036 		  PC GENERAL OPERATING SUPPORT 6,000,000

GATES PHILANTHROPY PARTNERS

PO BOX 23350
SEATTLE,WA98102 		  PC BUILD NEXT-GENERATION SEQUENCING CAPACITY FOR DETECTING PATHOGENS 1,497,909

GENESIS LA ECONOMIC GROWTH CORPORATION

801 SOUTH GRAND AVE 775
LOS ANGELES,CA90017 		  PC CONNECTING CAPITAL & COMMUNITY (3C) INITIATIVE 500,000

GREAT PLAINS INSTITUTE FOR SUSTAINABLE DEVELOPMENT

2801 21ST AVE S
MINNEAPOLIS,MN55407 		  PC CARBON MANAGEMENT PROGRAM 818,750

GREATSCHOOLS INC

2201 BROADWAY 4TH FLOOR
OAKLAND,CA94612 		  PC INCORPORATION OF NEW MEASURES AND DIVERSIFYING COMMUNITY VOICES 500,000

GRIPTAPE INC

60 PARK TERRACE WEST A21
NEW YORK,NY10034 		  PC GENERAL OPERATING SUPPORT 700,000

HAWAII COMMUNITY FOUNDATION

827 FORT STREET MALL
HONOLULU,HI96813 		  PC CHAN ZUCKERBERG KAUAI COMMUNITY FUND 300,000

HAWAII COMMUNITY FOUNDATION

827 FORT STREET MALL
HONOLULU,HI96813 		  PC CHAN ZUCKERBERG KAUAI COMMUNITY FUND 1,250,000

HAWAII COMMUNITY FOUNDATION

827 FORT STREET MALL
HONOLULU,HI96813 		  PC CHAN ZUCKERBERG KAUAI COMMUNITY FUND 2,522,381

HIGHLANDER RESEARCH & EDUCATION CENTER INC

1959 HIGHLANDER WAY
NEW MARKET,TN37820 		  PC POWER U 500,000

HOWARD UNIVERSITY

2400 6TH ST NW
WASHINGTON,DC20059 		  PC ACCELERATE GENOMICS RESEARCH AND PRECISION HEALTH FOR EVERYONE 2,300,000

HUMAN CELL ATLAS INC

415 MAIN ST
CAMBRIDGE,MA02142 		  PC GENERAL OPERATING SUPPORT 500,000

HUMAN CELL ATLAS INC

415 MAIN ST
CAMBRIDGE,MA02142 		  PC HUMAN CELL ATLAS DATA ECOSYSTEM 1,100,000

INDEPENDENT SCHOOL DISTRICT NO 535

615 7TH ST SW
ROCHESTER,MN55902 		  GOV SUPPORT A RESEARCH-TO-PRACTICE PARTNERSHIP THAT ALIGNS WITH THE IMPLEMENTATION OF THE DISTRICT'S REFRESHED STRATEGIC PLAN 496,100

INNOVATE PUBLIC SCHOOLS

SOBRATO CENTER FOR NONPROFITS
SAN JOSE,CA95126 		  PC GENERAL OPERATING SUPPORT 1,000,000

INSTRUCTION PARTNERS

604 GALLATIN AVE STE 202
NASHVILLE,TN37206 		  PC RESEARCH PARTNERSHIPS WITH SCHOOL DISTRICTS AS THEY ELEVATE STUDENT VOICE 370,000

INTERNATIONAL SOCIETY FOR TECHNOLOGY IN EDUCATION

621 SW MORRISON ST STE 800
PORTLAND,OR97205 		  PC EDSURGE INITIATIVE 700,000

KINGMAKERS OF OAKLAND

745 ARIMO AVE
OAKLAND,CA94610 		  PC GENERAL OPERATING SUPPORT 1,000,000

KNOWLEDGEWORKS FOUNDATION

ONE WEST 4TH ST
CINCINNATI,OH45202 		  PC PARTNERSHIP WITH THE KENTUCKY DEPARTMENT OF EDUCATION ON DISTRICT INNOVATION AROUND ASSESSMENT REDESIGN 1,096,171

LATINOS FOR EDUCATION INC

275 PAYSON RD
BELMONT,MA02478 		  PC GENERAL OPERATING SUPPORT 1,000,000

LEADING EDUCATORS INC

1824 ORETHA CASTLE HALEY BLVD
NEW ORLEANS,LA70113 		  PC GENERAL OPERATING SUPPORT 700,000

LEARNING POLICY INSTITUTE

1530 PAGE MILL RD STE 200
PALO ALTO,CA94304 		  PC CREATE PROTOTYPES AND INFORM POLICY FOR PERFORMANCE-BASED ASSESSMENT SYSTEMS IN SCIENCE 1,500,000

LOCAL MEDIA FOUNDATION

PO BOX 450
LAKE CITY,MI49651 		  SO I WORD IN BLACK PROJECT 335,000

M E B ALLIANCE FOR EDUCATOR DIVERSITY INC

7500 RIALTO BLVD STE 270
AUSTIN,TX78735 		  PC GENERAL OPERATING SUPPORT 1,500,000

MEHARRY MEDICAL COLLEGE

1005 DR DB TODD JR BLVD
NASHVILLE,TN37208 		  PC ACCELERATE GENOMICS RESEARCH AND PRECISION HEALTH FOR EVERYONE 2,300,000

NACA-INSPIRED SCHOOLS NETWORK

1000 INDIAN SCHOOL RD NW
ALBUQUERQUE,NM87104 		  PC BUILD OUT LAND-BASED HEALING AND LEARNING PRACTICES 650,000

NATIONAL BOARD FOR PROFESSIONAL TEACHING STANDARDS INC

1525 WILSON BLVD STE 700
ARLINGTON,VA22209 		  PC GENERAL OPERATING SUPPORT 1,000,000

NATIONAL CENTER FOR CIVIC INNOVATION INC

121 SIXTH AVE
NEW YORK,NY10013 		  PC CENTER FOR MEASUREMENT JUSTICE 2,000,000

NATIONAL PUBLIC EDUCATION SUPPORT FUND

1425 K ST STE 700
WASHINGTON,DC20005 		  PC GENERAL OPERATING SUPPORT 1,000,000

NEW MERIDIAN CORPORATION

9390 RESEARCH BLVD
AUSTIN,TX78759 		  PC DEVELOPMENT AND PROTOTYPING OF ONGOING ASSESSMENTS FOR MATH AND ENGLISH 800,000

NEW SCHOOLS FUND

1616 FRANKLIN ST 2ND FLOOR
OAKLAND,CA94612 		  PC GENERAL OPERATING SUPPORT 4,000,000

NEW SCHOOLS FUND

1616 FRANKLIN ST 2ND FLOOR
OAKLAND,CA94612 		  PC DIVERSE LEADERS PROGRAM 1,000,000

OCEAN GENOMICS INC

4620 HENRY ST
PITTSBURGH,PA15213 		  NC OPEN SCIENCE 177,540

OUR TURN INC

PO BOX 2019
NEW YORK,NY10013 		  PC GENERAL OPERATING SUPPORT 750,000

OUR VOICE NUESTRA VOZ

3301 FRERET ST
NEW ORLEANS,LA70115 		  PC GENERAL OPERATING SUPPORT 400,000

PAHARA INSTITUTE

440 N BARRANCA AVE 2927
COVINA,CA91723 		  PC GENERAL OPERATING SUPPORT 750,000

PAVE INC

1805 7TH ST NW FLOOR 6
WASHINGTON,DC20001 		  PC GENERAL OPERATING SUPPORT 750,000

POSSIBILITY LABS

1410 FRANKLIN ST 135
SAN FRANCISCO,CA94109 		  PC CALIFORNIA COMMUNITY OWNERSHIP POOLED FUND 3,000,000

PRESIDENT AND FELLOWS OF HARVARD COLLEGE

1033 MASSACHUSETTS AVE STE 3
CAMBRIDGE,MA02140 		  PC CREATION OF OPPORTUNITY INSIGHTS INSTITUTE 2,500,000

PRESIDENT AND FELLOWS OF HARVARD COLLEGE

1033 MASSACHUSETTS AVE STE 3
CAMBRIDGE,MA02140 		  PC THE KEMPNER INSTITUTE FOR THE STUDY OF NATURAL AND ARTIFICIAL INTELLIGENCE 100,000,000

QUANSIGHT LLC

8656 W HIGHWAY 71 BLDG F200
AUSTIN,TX78735 		  NC OPEN SCIENCE 173,474

QUANSIGHT LLC

8656 W HIGHWAY 71 BLDG F200
AUSTIN,TX78735 		  NC OPEN SCIENCE 170,000

QUANSIGHT LLC

8656 W HIGHWAY 71 BLDG F200
AUSTIN,TX78735 		  NC OPEN SCIENCE 136,000

REGENTS OF THE UNIVERSITY OF CALIFORNIA AT SANTA CRUZ

1156 HIGH ST
SANTA CRUZ,CA95064 		  GOV HUMAN CELL ATLAS DATA ECOSYSTEM 1,175,000

REGENTS OF THE UNIVERSITY OF CALIFORNIA AT BERKELEY

1608 FOURTH ST
BERKELEY,CA94720 		  GOV INNOVATIVE GENOMICS INSTITUTE RESEARCH TO ENHANCE THE NATURAL ABILITY OF PLANTS AND SOIL MICROBES TO CAPTURE AND STORE CARBON 8,000,000

REGENTS OF THE UNIVERSITY OF CALIFORNIA LOS ANGELES

420 WESTWOOD PLAZA 4121 ENGINEERING
V
LOS ANGELES,CA90095 		  GOV DEVELOPMENT OF COURSEKATA HIGH SCHOOL COURSE 1,000,000

REGENTS OF THE UNIVERSITY OF CALIFORNIA LOS ANGELES

420 WESTWOOD PLAZA 4121 ENGINEERING
V
LOS ANGELES,CA90095 		  GOV INSTITUTE FOR CARBON MANAGEMENT FOR SEACHANGE 7,000,000

REGENTS OF THE UNIVERSITY OF MICHIGAN

3003 S STATE ST
ANN ARBOR,MI48109 		  GOV REFINE THE BELONGING CENTERED-INSTRUCTION COACHING MODEL 1,007,800

RESOLVE TO SAVE LIVES INC

85 BROAD ST STE 1626
NEW YORK,NY10004 		  PC GENERAL OPERATING SUPPORT 5,000,000

RICHMOND NEIGHBORHOOD HOUSING SERVICES INC

12972 SAN PABLO AVE
RICHMOND,CA94805 		  PC CREDIT ENHANCEMENT TO SUPPORT HOMEOWNERS 40,000

RISE COLORADO

1595 ELMIRA ST
AURORA,CO80010 		  PC GENERAL OPERATING SUPPORT 750,000

ROCKEFELLER PHILANTHROPY ADVISORS INC

6 W 48TH ST
NEW YORK,NY10036 		  PC DEVELOPING A FRAMEWORK FOR PRACTITIONERS: FACILITATING DESIGN AND PRACTICE IN WHOLE CHILD ASSESSMENTS PROJECT 1,100,000

ROCKEFELLER PHILANTHROPY ADVISORS INC

6 W 48TH ST
NEW YORK,NY10036 		  PC THE PARTNERSHIP FOR THE FUTURE OF LEARNING 600,000

SAN FRANCISCO GENERAL HOSPITAL FOUNDATION

PO BOX 410836
SAN FRANCISCO,CA94141 		  PC 2022 CAPITAL CAMPAIGN 5,000,000

SEARCH INSTITUTE

615 1ST AVE NORTHEAST 125
MINNEAPOLIS,MN55413 		  PC DEVELOPMENTAL RELATIONSHIPS FRAMEWORK 900,000

SEATTLE FOUNDATION

1601 FIFTH AVE
SEATTLE,WA98101 		  PC GRANTMAKERS FOR THRIVING YOUTH 2021-22 FUND 1,000,000

SURGE INSTITUTE

935 W CHESTNUT ST STE 515
CHICAGO,IL60642 		  PC GENERAL OPERATING SUPPORT 1,000,000

TEACH PLUS INCORPORATED

27 SCHOOL ST
BOSTON,MA02108 		  PC SUPPORT DISTRICT AND RESEARCH PARTNERSHIPS TO IMPLEMENT WHOLE CHILD PRACTICES 742,773

THE ASPEN INSTITUTE

2300 N ST
WASHINGTON,DC20037 		  PC EDUCATION AND SOCIETY PROGRAM 1,500,000

THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

STANFORD UNIVERSITY DEVELOPMENT
SERVICES
STANFORD,CA94305 		  PC LATTICE DATA CURATION THAT ENABLES COMMUNITY CONTRIBUTION TO INTEROPERABLE DATA RESOURCES 4,434,311

THE CHARACTER LAB INC

3675 MARKET ST STE 200
PHILADELPHIA,PA19104 		  PC ACCESS AND DIVERSIFICATION OF A RESEARCH NETWORK 750,000

THE FREEDOM BOUND CENTER

2574 21ST ST
SACRAMENTO,CA95818 		  PC YOUTH WELLNESS INDEX 325,000

THE JUST TRUST FOR EDUCATION

2530 MERIDIAN PKWY STE 300
DURHAM,NC27713 		  PC START-UP AND OPERATING COSTS 1,583,870

THE LEADERSHIP ACADEMY INC

4518 COURT SQUARE
LONG ISLAND CITY,NY11101 		  PC PILOT AN APPROACH TO SCHOOL AND SYSTEM LEADER SUPPORT 1,800,000

THE MOREHOUSE SCHOOL OF MEDICINE INC

720 WESTVIEW DR SW
ATLANTA,GA30310 		  PC ACCELERATE GENOMICS RESEARCH AND PRECISION HEALTH FOR EVERYONE 2,300,000

THE OAKLAND REACH

333 HEGENBERGER RD
OAKLAND,CA94621 		  PC GENERAL OPERATING SUPPORT 750,000

THE PRIMARY SCHOOL

1765 E BAYSHORE RD STE A2
EAST PALO ALTO,CA94303 		  PC GENERAL OPERATING SUPPORT 3,950,000

THE PRIMARY SCHOOL BAY AREA

1765 E BAYSHORE RD STE A2
EAST PALO ALTO,CA94303 		  PC GENERAL OPERATING SUPPORT 1,600,000

THE PRIMARY SCHOOL-EAST PALO ALTO

1765 E BAYSHORE RD STE A2
EAST PALO ALTO,CA94303 		  PC GENERAL OPERATING SUPPORT 8,075,000

THE SEATTLE FOUNDATION

1601 FIFTH AVE
SEATTLE,WA98101 		  PC GRANTMAKERS FOR THRIVING YOUTH POLICY WORKING GROUP 1,500,000

TIDES CENTER

PO BOX 29907
SAN FRANCISCO,CA94129 		  PC THE STARFISH INSTITUTE'S BEYOND100K WORK 1,500,000

TIDES CENTER

PO BOX 29907
SAN FRANCISCO,CA94129 		  PC ALL HOME TO SUPPORT THE BAY AREA HOMELESS PREVENTION PILOT 2,400,000

TIDES CENTER

PO BOX 29907
SAN FRANCISCO,CA94129 		  PC PROJECT EVIDENT 680,000

TRANSCEND INC

159 LINCOLN AVE
HASTINGS ON HUDSON,NY10706 		  PC EXPANDING PILOT OF WHOLE CHILD MODEL 300,000

TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA

3451 WALNUT ST
PHILADELPHIA,PA19104 		  PC NEURODEGENERATION WORK 500,000

UK MEDICAL RESEARCH COUNCIL

NORTH STAR AVE
SWINDON,ENGLANDSN2 1FL
UK 		  GOV UK BIOBANK REPEAT IMAGING PROJECT 437,744

UNIVERSITY OF CAPE TOWN

ANZIO RD
CAPE TOWN    
SF 		  PC ESTABLISHING A MICROSCOPY IMAGING HUB TO IMPROVE ACCESS TO IMAGING TECHNOLOGY, EXPERTISE, AND RESOURCES 1,589,221

UNIVERSITY OF HAWAII FOUNDATION

PO BOX 11270
HONOLULU,HI96828 		  PC MEDICAL TRAINING PROGRAM 1,383,806

UNIVERSITY OF HAWAII FOUNDATION

PO BOX 11270
HONOLULU,HI96828 		  PC OCEAN CONSERVATION AND RESEARCH 14,200,000

UNIVERSITY OF HOUSTON

4200 ELGIN ST
HOUSTON,TX77004 		  GOV NATIONAL CENTER FOR RESEARCH OF EDUCATOR DIVERSITY 750,000

UNIVERSITY OF SOUTHERN CALIFORNIA

1050 CHILDS WAY
LOS ANGELES,CA90089 		  PC CENTER FOR AFFECTIVE NEUROSCIENCE, DEVELOPMENT, LEARNING AND EDUCATION 500,000

VILLAGE OF WISDOM INC

600 E UMSTEAD AVE
DURHAM,NC27701 		  PC GENERAL OPERATING SUPPORT 750,000

WILCOX HEALTH FOUNDATION

3-3420 KUHIO HWY
LIHUE,HI96766 		  PC PURCHASE OF A CT SCANNER AT WILCOX HOSPITAL 1,806,150

WINDWARD FUND

1201 CONNECTICUT AVE NW
WASHINGTON,DC20036 		  PC CARBON TO SEA INITIATIVE 5,000,000

YALE UNIVERSITY

PO BOX 2038
NEW HAVEN,CT06521 		  PC YALE CENTER FOR EMOTIONAL INTELLIGENCE 1,216,508

YOUTH UNITED FOR CHANGE

520 N COLUMBUS BLVD STE 205
PHILADELPHIA,PA19123 		  PC GENERAL OPERATING SUPPORT 250,000

ZAPPYLAB INC DBA PROTOCOLSIO

2120 UNIVERSITY AVE STE 625
BERKELEY,CA94704 		  NC OPEN SCIENCE 907,400

UK BIOBANK LIMITED

UNITS 1-2 SPECTRUM WAY
STOCKPORT   SK3 0SA
UK 		  NC REPEAT IMAGING PROJECT 908,813
Total .................................right arrow 3a 364,708,682
bApproved for future payment

BARR CENTER
PO BOX 249 2355 FAIRVIEW AVE
ROSEVILLE,MN55430 		  PC IMPROVE PROCUREMENT FOR EVIDENCE-BASED PRACTICES THAT SUPPORT TEACHER AND STUDENT RELATIONSHIPS IN SCHOOLS 500,000

BROAD INSTITUTE INC
415 MAIN ST
CAMBRIDGE,MA02139 		  PC HUMAN CELL ATLAS DATA ECOSYSTEM 2,827,500

CAJON VALLEY UNION SCHOOL DISTRICT
750 E MAIN ST
EL CAJON,CA92020 		  GOV DEVELOP ASSESSMENTS AND INTEROPERABLE DATA VISUALIZATION TOOLS 600,000

CHARLES DREW UNIVERSITY OF SCIENCE & MEDICINE
1731 EAST 120TH ST
LOS ANGELES,CA90059 		  PC ACCELERATE GENOMICS RESEARCH AND PRECISION HEALTH FOR EVERYONE 9,200,000

CHILD TRENDS INC
7315 WISCONSIN AVE 1200
BETHESDA,MD20814 		  PC EVALUATION FOR AND IMPLEMENTATION OF STRONG LOGIC MODELS TO GENERATE EVIDENCE ALIGNED TO ESSA TIER 3 1,121,000

COLD SPRING HARBOR LABORATORY
1 BUNGTOWN RD
COLD SPRING HARBOR,NY11724 		  PC IMPROVE THE SUSTAINABILITY AND CAPACITY OF BIORXIV/MEDRXIV 2,000,000

EDUCATION LEADERS OF COLOR INC
3680 WILSHIRE BLVD STE P-04-1052
LOS ANGELES,CA90010 		  PC GENERAL OPERATING SUPPORT 2,000,000

EDUCATION TRAINING AND RESEARCH ASSOCIATES
5619 SCOTTS VALLEY DR
SCOTT VALLEY,CA95063 		  PC SUPPORT DISTRICT AND RESEARCH PARTNERSHIPS TO IMPLEMENT WHOLE CHILD PRACTICES 730,000

EQUAL OPPORTUNITY SCHOOLS
130 NICKERSON ST STE 200
SEATTLE,WA98109 		  PC MULTI-YEAR REDESIGN OF THE ACTION FOR EQUITY (A4E) SURVEY AND STUDENT INSIGHT CARD 2,600,000

EUROPEAN MOLECULAR BIOLOGY LABORATORY
MEYERHOFSTRASSE 1
HEIDELBERG   69117
GM 		  PC HUMAN CELL ATLAS DATA ECOSYSTEM 2,192,584

FELLOWSHIP FOR RACE & EQUITY IN EDUCATION
4828 ILLINOIS AVE NW
WASHINGTON,DC20011 		  PC GENERAL OPERATING SUPPORT 1,000,000

FPF EDUCATION AND INNOVATION FOUNDATION
1350 I ST NW STE 350
WASHINGTON,DC20005 		  PC GENERAL OPERATING SUPPORT 2,000,000

FRAMEWORKS INSTITUTE
1333 H ST NW
WASHINGTON,DC20005 		  PC FRAMING AND NARRATIVE STRATEGY DEVELOPMENT FOR ORGANIZATIONAL COMMUNICATIONS 451,000

GRIPTAPE INC
60 PARK TERRACE WEST A21
NEW YORK,NY10034 		  PC GENERAL OPERATING SUPPORT 1,400,000

HOWARD UNIVERSITY
2400 6TH ST NW
WASHINGTON,DC20059 		  PC ACCELERATE GENOMICS RESEARCH AND PRECISION HEALTH FOR EVERYONE 9,200,000

HUMAN CELL ATLAS INC
415 MAIN ST
CAMBRIDGE,MA02142 		  PC GENERAL OPERATING SUPPORT 500,000

HUMAN CELL ATLAS INC
415 MAIN ST
CAMBRIDGE,MA02142 		  PC HUMAN CELL ATLAS DATA ECOSYSTEM 3,400,000

INDEPENDENT SCHOOL DISTRICT NO 535
615 7TH ST SW
ROCHESTER,MN55902 		  GOV SUPPORT A RESEARCH-TO-PRACTICE PARTNERSHIP THAT ALIGNS WITH THE IMPLEMENTATION OF THE DISTRICT'S REFRESHED STRATEGIC PLAN 726,320

INSTRUCTION PARTNERS
604 GALLATIN AVE STE 202
NASHVILLE,TN37206 		  PC RESEARCH PARTNERSHIPS WITH SCHOOL DISTRICTS AS THEY ELEVATE STUDENT VOICE 730,000

LATINOS FOR EDUCATION INC
275 PAYSON RD
BELMONT,MA02478 		  PC GENERAL OPERATING SUPPORT 2,000,000

MEHARRY MEDICAL COLLEGE
1005 DR DB TODD JR BLVD
NASHVILLE,TN37208 		  PC ACCELERATE GENOMICS RESEARCH AND PRECISION HEALTH FOR EVERYONE 9,200,000

NACA-INSPIRED SCHOOLS NETWORK
1000 INDIAN SCHOOL RD NW
ALBUQUERQUE,NM87104 		  PC BUILD OUT LAND-BASED HEALING AND LEARNING PRACTICES 850,000

NATIONAL BOARD FOR PROFESSIONAL TEACHING STANDARDS INC
1525 WILSON BLVD STE 700
ARLINGTON,VA22209 		  PC GENERAL OPERATING SUPPORT 2,000,000

REGENTS OF THE UNIVERSITY OF CALIFORNIA AT BERKELEY
1608 FOURTH ST
BERKELEY,CA94720 		  GOV INNOVATIVE GENOMICS INSTITUTE RESEARCH TO ENHANCE THE NATURAL ABILITY OF PLANTS AND SOIL MICROBES TO CAPTURE AND STORE CARBON 3,000,000

REGENTS OF THE UNIVERSITY OF CALIFORNIA AT SANTA CRUZ
1156 HIGH ST
SANTA CRUZ,CA95064 		  GOV HUMAN CELL ATLAS DATA ECOSYSTEM 2,350,000

REGENTS OF THE UNIVERSITY OF MICHIGAN
3003 S STATE ST
ANN ARBOR,MI48109 		  GOV REFINE THE BELONGING CENTERED-INSTRUCTION COACHING MODEL 492,200

RESOLVE TO SAVE LIVES INC
85 BROAD ST STE 1626
NEW YORK,NY10004 		  PC GENERAL OPERATING SUPPORT 20,000,000

ROCKEFELLER PHILANTHROPY ADVISORS INC
6 W 48TH ST
NEW YORK,NY10036 		  PC DEVELOPING A FRAMEWORK FOR PRACTITIONERS: FACILITATING DESIGN AND PRACTICE IN WHOLE CHILD ASSESSMENTS PROJECT 265,000

SAN FRANCISCO GENERAL HOSPITAL FOUNDATION
PO BOX 410836
SAN FRANCISCO,CA94141 		  PC 2022 CAPITAL CAMPAIGN 25,000,000

SURGE INSTITUTE
935 W CHESTNUT ST STE 515
CHICAGO,IL60642 		  PC GENERAL OPERATING SUPPORT 2,000,000

TEACH PLUS INCORPORATED
27 SCHOOL ST
BOSTON,MA02108 		  PC SUPPORT DISTRICT AND RESEARCH PARTNERSHIPS TO IMPLEMENT WHOLE CHILD PRACTICES 357,227

THE MOREHOUSE SCHOOL OF MEDICINE INC
720 WESTVIEW DR SW
ATLANTA,GA30310 		  PC ACCELERATE GENOMICS RESEARCH AND PRECISION HEALTH FOR EVERYONE 9,200,000

THE PRIMARY SCHOOL
1765 E BAYSHORE RD STE A2
EAST PALO ALTO,CA94303 		  PC GENERAL OPERATING SUPPORT 670,000

THE PRIMARY SCHOOL - BAY AREA
1765 E BAYSHORE RD STE A2
EAST PALO ALTO,CA94303 		  PC GENERAL OPERATING SUPPORT 240,000

THE PRIMARY SCHOOL-EAST PALO ALTO
1765 E BAYSHORE RD STE A2
EAST PALO ALTO,CA94303 		  PC GENERAL OPERATING SUPPORT 4,365,000

TIDES CENTER
PO BOX 29907
SAN FRANCISCO,CA94129 		  PC PROJECT EVIDENT 1,120,000

UNIVERSITY OF CAPE TOWN
ANZIO RD
CAPE TOWN    
SF 		  PC ESTABLISHING A MICROSCOPY IMAGING HUB TO IMPROVE ACCESS TO IMAGING TECHNOLOGY, EXPERTISE, AND RESOURCES 393,933

YALE UNIVERSITY
PO BOX 2038
NEW HAVEN,CT06521 		  PC YALE CENTER FOR EMOTIONAL INTELLIGENCE 4,410,430
Total ................................. right arrow 3b 131,092,194
Form 990-PF (2022)
Page 12
Form 990-PF (2022)
Page 12
Part XV-A
Analysis of Income-Producing Activities
Enter gross amounts unless otherwise indicated. Unrelated business income Excluded by section 512, 513, or 514 (e)
Related or exempt
function income
(See instructions.)
1Program service revenue: (a)
Business code 		(b)
Amount 		(c)
Exclusion code 		(d)
Amount
a
b
c
d
e
f
gFees and contracts from government agencies          
2 Membership dues and assessments ....          
3 Interest on savings and temporary cash
investments ........... 		         
4 Dividends and interest from securities .... 901101 165,044 14 10,335,195  
5 Net rental income or (loss) from real estate:
aDebt-financed property......          
bNot debt-financed property.....          
6 Net rental income or (loss) from personal property          
7 Other investment income .....     14 32,562,159  
8 Gain or (loss) from sales of assets other than
inventory ............ 		901101 681,492 18 -194,491,944  
9 Net income or (loss) from special events:          
10 Gross profit or (loss) from sales of inventory          
11 Other revenue:
aALTERNATIVE INVESTMENTS 		901101 -2,120,744 14    
b
c
d
e
12 Subtotal. Add columns (b), (d), and (e) .. -1,274,208 -151,594,590 0
13Total. Add line 12, columns (b), (d), and (e)..................
13
-152,868,798
(See worksheet in line 13 instructions to verify calculations.)
Part XV-B
Relationship of Activities to the Accomplishment of Exempt Purposes
Line No.
DownArrow 		Explain below how each activity for which income is reported in column (e) of Part XV-A contributed importantly to
the accomplishment of the foundation’s exempt purposes (other than by providing funds for such purposes). (See
instructions.)
Form 990-PF (2022)
Page 13
Form 990-PF (2022)
Page 13
Part XVI
Information Regarding Transfers To and Transactions and Relationships With Noncharitable Exempt Organizations
1
Did the organization directly or indirectly engage in any of the following with any other organization described in section 501(c) (other than section 501(c)(3) organizations) or in section 527, relating to political organizations?
Yes
No
a
Transfers from the reporting foundation to a noncharitable exempt organization of:
(1) Cash...................................
1a(1)
 
No
(2) Other assets.................................
1a(2)
 
No
b
Other transactions:
(1) Sales of assets to a noncharitable exempt organization....................
1b(1)
 
No
(2) Purchases of assets from a noncharitable exempt organization..................
1b(2)
 
No
(3) Rental of facilities, equipment, or other assets.......................
1b(3)
 
No
(4) Reimbursement arrangements...........................
1b(4)
 
No
(5) Loans or loan guarantees.............................
1b(5)
 
No
(6) Performance of services or membership or fundraising solicitations................
1b(6)
 
No
c
Sharing of facilities, equipment, mailing lists, other assets, or paid employees..............
1c
 
No
d
If the answer to any of the above is "Yes," complete the following schedule. Column (b) should always show the fair market value
of the goods, other assets, or services given by the reporting foundation. If the foundation received less than fair market value
in any transaction or sharing arrangement, show in column (d) the value of the goods, other assets, or services received.
(a) Line No. (b) Amount involved (c) Name of noncharitable exempt organization (d) Description of transfers, transactions, and sharing arrangements
2a
Is the foundation directly or indirectly affiliated with, or related to, one or more tax-exempt organizations
described in section 501(c) (other than section 501(c)(3)) or in section 527? ...........
b
If "Yes," complete the following schedule.

(a) Name of organization (b) Type of organization (c) Description of relationship
THE PRIMARY SCHOOL LAB 501(C)(4) COMMON CONTROL - SEE STATEMENT 19
FWDUS INC 501(C)(4) COMMON CONTROL - SEE STATEMENT 19
CHAN ZUCKERBERG INITIATIVE ADVOCACY 501(C)(4) COMMON CONTROL - SEE STATEMENT 19
Sign Here
Under penalties of perjury, I declare that I have examined this return, including accompanying schedules and statements, and to the best of my knowledge and belief, it is true, correct, and complete. Declaration of preparer (other than taxpayer) is based on all information of which preparer has any knowledge.
right arrow 2023-11-15 right arrow
May the IRS discuss this return
with the preparer shown below?
See instructions.
Signature of officer or trustee Date Title
Paid Preparer Use Only Print/Type preparer's name DAVID M HIGHFILL Preparer's Signature   Date   Check if self-
employed right arrow		 PTIN P01517891
Firm's name SmallBulletKPMG LLP
  		Firm's EIN SmallBullet13-5565207  
Firm's address SmallBullet550 S HOPE STREET STE 1500
 
LOS ANGELES, CA90071
 Phone no. (213) 972-4000
Form 990-PF (2022)
Additional Data


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