Nonprofits in South Carolina
The IRS lists 34,194 active tax-exempt organizations operating in South Carolina, including 29,879 501(c)(3)s, to which you can make a tax-deductible donation. South Carolina nonprofit organizations reported $42.6 billion in revenue on their most recent tax filings.
Highest-Revenue Nonprofits in South Carolina
Figures are based on the most recently reported revenue for each organization. Nonprofits may take anywhere from a few months to more than a year to submit their tax information, depending on the size of the organization and other factors.
| Organization | Total Revenue | Year |
|---|---|---|
| Advanced Technology International | $4,870,021,886 | 2025 |
| Prisma Health - Upstate | $3,605,252,123 | 2025 |
| Prisma Health-midlands | $2,076,553,749 | 2025 |
| Lexington Health Inc | $1,768,647,290 | 2025 |
| Central Electric Power Cooperative Inc | $1,607,586,867 | 2024 |
| Mcleod Regional Medical Center Of The Pee Dee Inc | $1,494,230,490 | 2025 |
| Prisma Health-university Medical Group | $925,799,575 | 2025 |
| Anmed Health | $854,590,129 | 2024 |
| St Francis Hospital Inc | $850,947,341 | 2024 |
| Bon Secours-st Francis Xavier Hospital Inc | $620,583,353 | 2024 |
Highest-Earning Nonprofit Employees in South Carolina
Salary figures are based on the most recently reported tax year for each organization. Nonprofits may take anywhere from a few months to more than a year to submit their tax information, depending on the size of the organization and other factors.
Nonprofits also report salaries from related organizations, as well as other benefits and bonuses, which are shown below the listed compensation if they are reported.
| Employee | Compensation | Year |
|---|---|---|
|
Mark S O'halla
(President And Ceo Of Prisma Health) Prisma Health |
$3,807,923
Other: -$433,472
|
2025 |
|
Tod Augsburger
(President And Ceo) Lexington Health Inc |
$3,468,120
Other: $793,703
|
2025 |
|
Donna C Isgett
(President/ceo) Mcleod Health |
$2,187,646
Other: $242,410
|
2025 |
|
George Khoury Md
(Neurosurgeon) Roper Saint Francis Physicians Network |
$2,116,234
Other: $50,666
|
2024 |
|
John Womack Md
(Orthopedic Surgeon) Bon Secours Medical Group Greenville Specialty Care Llc |
$2,087,940
Other: $73,279
|
2024 |
|
Elmer Holstien
(President/ceo) Apella Health Management Inc |
$2,072,543
Other: $661,502
|
2025 |
|
Jeffrey Dilisi
(Former President/ceo Rsfh) Roper St Francis Healthcare |
$2,056,692
Other: $11,719
|
2024 |
|
Bertram Richter
(Physician) Prisma Health Medical Group-midlands |
$1,929,426
Other: $87,834
|
2025 |
|
Dr Charles P Toussaint
(Physician) Lexington Health Inc |
$1,897,695
Other: $85,070
|
2025 |
|
William Naso Md
(Staff Physician) Mcleod Physician Associates Ii |
$1,890,938
Other: $29,260
|
2025 |
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