Listing all stimulus spending by amount, in descending order. Return to National Institutes of Health page
Amount refers to both the amount of stimulus funding going toward the project and the face value of the loan.
| Recipient | Amount | Type | Description | Federal Dept./Agency | Date |
|---|---|---|---|---|---|
| UNIVERSITY OF ROCHESTER | $767,292 | Grant | Trans-NIH Recovery Act Research Support: This application is a revised competitive renewal of our grant that is focused on understanding the mechanisms by which mutant huntingtin impairs mitochondrial function. In March 2007 I relocated to the University of Rochester specifically to join the Mit | Health and Human Services, Department of / National Institutes of Health | 8/05/2009 |
| UNIVERSITY OF CHICAGO, THE | $692,357 | Grant | Trans-NIH Recovery Act Research Support: The ultimate goal of this project is to understand the structure of intermediates of fibrillogenesis, focusing on -amyloid (A) of Alzheimer's Disease (AD). The specific aims of this proposal are as follows: 1. To examine, by solid-state NMR, A1-40 fibrils | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $732,292 | Grant | Trans-NIH Recovery Act Research Support: This proposal has the objective to develop a rational treatment approach for patients with malignant glial-derived brain tumors (glioma). Gliomas and are among the most difficult cancers to treat and typical symptoms include intractable headaches and epil | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| UNIVERSITY OF CONNECTICUT | $749,438 | Grant | Trans-NIH Recovery Act Research Support: In multiple sclerosis and other inflammatory disorders of the central nervous system, white blood cells leave the circulation and invade the brain and/or spinal cord, where they cause significant destruction of nerve cells leading to severe difficulties i | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| SEATTLE CHILDREN'S HOSPITAL | $1,047,700 | Grant | Trans-NIH Recovery Act Research Support: Developmental Pathways in the Nervous System -- The development of the vertebrate nervous system requires the generation of a large number of different types of neurons, characterized by the specific expression of neurotransmitters and their recept | Health and Human Services, Department of / National Institutes of Health | 9/20/2009 |
| DANA-FARBER CANCER INSTITUTE, INC. | $813,845 | Grant | Trans-NIH Recovery Act Research Support: How cells regulate and execute cytokinesis, the final step in cell division, remains one of the major unsolved questions in basic biology. Our long-term goal is the systematic dissection of temporal and spatial control during cytokinesis. It has been chal | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | $222,750 | Grant | Trans-NIH Recovery Act Research Support: Chagas disease, caused by Trypanosoma cruzi, causes nearly 50,000 deaths a year in Latin America and is a concern in the United States (US) because of the high prevalence of T. cruzi in wildlife, presence of competent reduviid vectors, high numbers of inf | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| MICHIGAN TECHNOLOGICAL UNIVERSITY | $206,654 | Grant | Trans-NIH Recovery Act Research Support: Menisci function to distribution load and increase stability of the knee joint. Both partial and complete meniscectomy have been shown to increase the incidence of osteoarthritis. Meniscal replacement with allograft, synthetic or tissue engineered replace | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF PACIFIC | $191,250 | Grant | Trans-NIH Recovery Act Research Support: Several lines of evidence suggest that there is a fundamental relationship between blood flow and secretory function in salivary glands, and it has been hypothesized that salivary hypofunction in diabetic patients results in part from abnormalities in blo | Health and Human Services, Department of / National Institutes of Health | 4/27/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $102,208 | Grant | Trans-NIH Recovery Act Research Support: Viral evasion of global RNA turnover during gammaherpesvirus lytic infection. Our understanding of the life cycle of cancer-causing gammaherpesviruses is limited. We will attempt to elucidate the means by which these viruses actively replicate while subve | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| BAYLOR COLLEGE OF MEDICINE | $104,733 | Grant | Trans-NIH Recovery Act Research Support: 'The purpose of this grant is to determine the effect of HAART on HPV infection and HPV-related anal dysplasia in HIV-infected individuals.Abstract: HIV-infected individuals have improved survival in the highly active antiretroviral therapy (HAART) era, b | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $52,719 | Grant | Trans-NIH Recovery Act Research Support: The research projects focus on the interrelationships between age-related changes in auditory and cognitive function and their contributions to changes in communication abilities of older adults. Knowledge of the auditory and cognitive factors contributin | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $86,400 | Grant | Trans-NIH Recovery Act Research Support: ESCRIPTION (provided by applicant): Amyotrophic Lateral Sclerosis (ALS) is an untreatable neurodegenerative disorder characterized by progressive loss of motor neuron function. Respiratory failure is the most common cause of ALS patient death. Treatment o | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $44,170 | Grant | Trans-NIH Recovery Act Research Support: The present supplement application seeks support for summer research experiences at The Scripps Research Institute for two talented high school interns in the San Diego area. The work to be performed by the interns is directly relevant to the studies and | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $75,000 | Grant | Trans-NIH Recovery Act Research Support: To achieve normal growth, development, and quality of life, individuals must maintain adequate intake of nutrition and be free from prolonged metabolic derangement. Unfortunately, people affected with either acute or chronic diseases often show disorders | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF ARIZONA | $142,259 | Grant | Trans-NIH Recovery Act Research Support: Diabetes and congestive heart failure are diseases that have been associated with defects in the handling of salt and water by the kidney. Common in individuals with these disorders are elevated circulating levels of vasopressin, the peptide hormone that | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $97,268 | Grant | Trans-NIH Recovery Act Research Support: This grant provides equipment. We have purchased a cryostat and submitted the paperwork to purchase a microscope as requested in the proposal. We requested funds to purchase the following three equipment items, which are necessary to perform the two S | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $27,962 | Grant | Trans-NIH Recovery Act Research Support: Summer Educator Award. This administrative supplement request focuses on the regulation of virulence factors by intracellular NAD+ concentration. We have shown that virulence associated adhesin genes are transcriptionally induced in response to low enviro | Health and Human Services, Department of / National Institutes of Health | 7/21/2009 |
| YALE UNIVERSITY | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The goals of the parent grant are to determine the function(s) of P2Y receptors and downstream cytosolic Ca2+ signals in hepatic stellate cell (HSC) function. HSC are important mediators of liver fibrosis, but their regulation is only partially understood | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF CINCINNATI | $73,481 | Grant | Trans-NIH Recovery Act Research Support: Zetia (Ezetimibe) inhibits cholesterol absorption via inhibition of NPC1-L1 mediated cholesterol transport pathway(s) in the enterocytes. We demonstrated that CD36 also plays a role in cholesterol absorption. It has also been demonstrated that the scaveng | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF PITTSBURGH THE | $60,000 | Grant | Trans-NIH Recovery Act Research Support: The Oroboros Oxygraph-2K that will be purchased with the supplemental funds will provide the addition of high-resolution respirometry measurements of mitochondria function in human biopsy samples obtained in the parent project. | Health and Human Services, Department of / National Institutes of Health | 7/21/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $31,046 | Grant | Trans-NIH Recovery Act Research Support: Obesity and overweight affects most Americans, but there are some who resist obesity, just as some animals resist obesity. Animal and human studies indicate that spontaneous physical activity (SPA), which generates nonexercise activity thermogenesis (NEAT | Health and Human Services, Department of / National Institutes of Health | 6/22/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $75,000 | Grant | Trans-NIH Recovery Act Research Support: This award partially funds the project entitled,informational and financial interventions to enhance African Americans? consideration of Live Kidney Donation/ Living Related Kidney Transplant . The parent award is funding the development and testing of a | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| MIDDLE TENNESSEE STATE UNIVERSITY | $186,096 | Grant | Trans-NIH Recovery Act Research Support: The focus of this project is the further development of a concise and versatile route for the preparation of differentially substituted heteroaromatics based on the regioselective one-pot polycoupling of polyhalogenated heteroaromatics. The basic advantag | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| SOUTHERN ILLINOIS UNIVERSITY | $218,250 | Grant | Trans-NIH Recovery Act Research Support: Two million Americans suffer a moderate to severe traumatic brain injury (TBI) each year. In addition, current military action is resulting in a large spike in the number of additional TBI cases. These injuries produce enduring disabilities that include c | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| IMMPORT THERAPEUTICS, INC. | $1,847,306 | Grant | Trans-NIH Recovery Act Research Support: Throughout the World Chlamydia trachomatis is the most common sexually transmitted bacterial pathogen. In areas with poor sanitary conditions C. trachomatis causes trachoma the most common cause of preventable blindness in the World. In symptomatic cases, | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| KITWARE, INC. | $1,099,924 | Grant | Trans-NIH Recovery Act Research Support: High Throughput Web-based Image Analysis of Mouse Brain MR Imaging Studies Project Narrative The shapes of structures in the human brain, imaged using MRI, have been associated with a multitude of pathologies and drug-related effects in psychiatric resear | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| INNOVATIVE SURFACE TECHNOLOGIES, INC | $749,993 | Grant | Trans-NIH Recovery Act Research Support: This SBIR project is designed to develop and demonstrate photoreactive nanofibers for tissue engineering scaffolds. Tissue engineering offers the possibility of aiding regeneration of tissue damaged by disease or trauma and, in some cases, of creating new | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $293,120 | Grant | Trans-NIH Recovery Act Research Support: The primary objective of the current research program is to define and characterize the molecular basis for innate resistance and susceptibility of inbred strains of the snail Biomphalaria glabrata to infection by larvae of the human blood fluke Schistoso | Health and Human Services, Department of / National Institutes of Health | 6/18/2009 |
| UNIVERSITY OF ILLINOIS | $392,500 | Grant | Trans-NIH Recovery Act Research Support: Chemoattractant-induced phagocyte activation is an important mechanism of host defense. In phagocytes, induced activation of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase leads to robust production of reactive oxygen species (ROS), which | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| UNIVERSITY OF CHICAGO, THE | $375,272 | Grant | Trans-NIH Recovery Act Research Support: Staphylococcus aureus is the leading cause of community and nosocomially-acquired infectious and toxin-mediated syndromes, some life-threatening that affect patients of all ages. As a species, S. aureus has become resistant to antibiotics of all classes | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $366,146 | Grant | Trans-NIH Recovery Act Research Support: M. tuberculosis (Mtb) is one of the leading causes of death worldwide and claims millions of lives annually. Approximately ~1.7 billion people worldwide are asymptomatically infected with the tubercle bacillus and constitute a major impediment to worldwid | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $187,665 | Grant | Trans-NIH Recovery Act Research Support: Despite significant efforts, our understanding of clinically relevant mechanisms underlying human pituitary tumorigenesis remains ashamedly meager. My lab has focused on defining the precise molecular mechanisms by which ubiquitous components of growth fa | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| THE CHILDREN'S HOSPITAL OF PHILADELPHIA | $164,500 | Grant | Trans-NIH Recovery Act Research Support: The overall aim of this proposal is to elucidate the mechanism(s) regulating hepatic urea synthesis in case of nonalcoholic fatty liver disease (NAFLD) or metabolic syndrome. The long-term goal is to develop a clinically applicable protocol to improve ure | Health and Human Services, Department of / National Institutes of Health | 6/08/2009 |
| RHODE ISLAND HOSPITAL | $192,888 | Grant | Trans-NIH Recovery Act Research Support: According to the World Health Organization, obesity in developed countries has reached epidemic proportions. There are globally more than 1 billion adults overweight, with around 300 million of them clinically obese. As consequence, the study of obesity h | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| DUKE UNIVERSITY | $637,594 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this predoctoral and postdoctoral research training program is to provide rigorous training in the general fields of social, medical, and economic demography of aging. A major focus is placed on five substantive areas: a) biodemography, inc | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| RUSH UNIVERSITY MEDICAL CENTER | $281,102 | Grant | Trans-NIH Recovery Act Research Support: This grant provides funds for training five pre-doctoral students in disease oriented basic neuroscience with an emphasis on aging and age-related neurological disorders. The program is designed to offer Ph.D. students rigorous and specialized training i | Health and Human Services, Department of / National Institutes of Health | 5/19/2009 |
| UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON | $409,756 | Grant | Trans-NIH Recovery Act Research Support: This application requests five years of funding for the UTMB training program in Health of Older Minorities. This program was originally funded in 1999 and now supports three pre-doctoral and three postdoctoral positions. In this application we are reques | Health and Human Services, Department of / National Institutes of Health | 5/19/2009 |
| THOMAS JEFFERSON UNIVERSITY | $154,500 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement supports a new pilot funding program in Translational Cancer Medicine that will effectively leverage scientific activities within the research programs of the Kimmel Cancer Center. As with many Cancer Centers, a key rate-li | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| YALE UNIVERSITY | $62,250 | Grant | Trans-NIH Recovery Act Research Support: Tfiis is a K99 to ROO transition application which seeks further support for studying the association of four opioid receptor genes (0PRM1, 0PRD1, 0PRK1, and 0PRL1) and four opioid peptide genes (POMC, PDYN, PENK, and PNOC) genes and substance dependence | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $36,180 | Grant | Trans-NIH Recovery Act Research Support: The development of alcoholism related traits is believed to be caused by both genetic and environmental factors, in addition to their interactions. Genetic variations associated with alcoholism related traits can affect several different mechanisms, inclu | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| MEHARRY MEDICAL COLLEGE | $99,838 | Grant | Trans-NIH Recovery Act Research Support: This is a supplement to the K01 Regulation of Prostate Cancer Growth by PPARg ligands grant. This supplement will advance knowledge on how agonists for peroxisome proliferator activated receptor gamma proteins reduces the growth of prostate cancer cells. | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF TEXAS M.D. ANDERSON CANCER CENTER, THE | $97,238 | Grant | Trans-NIH Recovery Act Research Support: My ultimate objective is to conduct effective, independent research in cancer prevention and control, focusing on behavioral science applications for underserved populations, beginning with studying Hispanic cancer survivors. Specifically, I wish to devel | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| TRUSTEES OF TUFTS COLLEGE INC | $54,000 | Grant | Trans-NIH Recovery Act Research Support: Cryptosporidiosis is an opportunistic infection caused by Cryptosporidium parvum or C. hominis in humans. We propose to study the role of key antigen presenting cells and dendritic cells in stimulating anti-parasite immunity in cryptosporidiosis. | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $53,536 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this study is to compare 5 to 12 year old siblings who are discordant in their weight status (i.e., normal weight or overweight obese) on select eating traits both under laboratory and free living conditions. We are requesting an Administr | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| CORNELL UNIVERSITY, INC | $54,000 | Grant | Trans-NIH Recovery Act Research Support: In the spirit of the American Recovery and Reinvestment Act (ARRA) of 2009, this supplemental award aims to create a job for a research technician who will accelerate the tempo of research of the parent grant (1 K01 DK080194-01). The parent grant is expl | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| DANA-FARBER CANCER INSTITUTE, INC. | $92,607 | Grant | Trans-NIH Recovery Act Research Support: The goal of the proposed research is to characterize novel isoenzyme-selective inhibitors of histone deacetylase 6 (HDAC6) to enable human clinical investigation. Following proteasome inhibition, perinuclear aggregates of insoluble ubiquitinated proteins | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| DUKE UNIVERSITY | $54,000 | Grant | Trans-NIH Recovery Act Research Support: We are requesting funds in this administrative supplement to accelerate the pace of research proposed in our K08 award. We have been working to determine the importance of HCV Core domain 3 in the accumulation of intracellular lipid. We have addressed mos | Health and Human Services, Department of / National Institutes of Health | 8/24/2009 |
| CHILDREN'S HOSPITAL CORPORATION, THE | $54,000 | Grant | Trans-NIH Recovery Act Research Support: With the increased use of prenatal screening by ultrasound, more fetuses are being diagnosed as potentially having congenital renal obstruction (2-5% of all pregnancies in the US). To date, the most common cause of renal failure in children is from renal | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| PENNSYLVANIA STATE UNIVERSITY, THE | $54,000 | Grant | Trans-NIH Recovery Act Research Support: Hepatitis C virus (HCV) is a leading cause of liver cancer worldwide. During infection, HCV induces the formation of rearranged membrane structures termed web. These membranes are also observed in vitro following expression of HCV NS4B protein alone. Vari | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO ,THE | $78,647 | Grant | Trans-NIH Recovery Act Research Support: Progression and metastasis of solid tumors is a principal cause of death for cancer patients. The childhood muscle cancer alveolar rhabdomyosarcoma is a classic example. A gap in understanding the disease-specific mechanisms of progression underlies the d | Health and Human Services, Department of / National Institutes of Health | 9/02/2009 |
| DUKE UNIVERSITY | $407,160 | Grant | Trans-NIH Recovery Act Research Support: NOT-OD-09-058: NIH Announces the Availability of Recovery Act Funds for Administrative Supplements This Administrative Supplement proposes feasible aims that will enhance all of our funded NIH grants but especially the highly significant parent grant wher | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER | $33,413 | Grant | Trans-NIH Recovery Act Research Support: The research project is on the development a vaccine against schistosome infection which affects over 200 million people with an additional 790 million at risk in 74 countries. Two High School Biology teachers from Lubbock High School worked as Research A | Health and Human Services, Department of / National Institutes of Health | 6/03/2009 |
| VIRGINIA COMMONWEALTH UNIVERSITY | $69,453 | Grant | Trans-NIH Recovery Act Research Support: Human granulocytic anaplasmosis (HGA; formerly human granulocytic ehrlichiosis) is an emerging and potentially fatal disease and the second most common tick-borne infection in the United States. The etiologic agent is Anaplasma phagocytophilum, an obligat | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| PENNSYLVANIA STATE UNIVERSITY, THE | $113,250 | Grant | Trans-NIH Recovery Act Research Support: Asthma affects millions of people worldwide and has been gaining prevalence in the US. Symptoms of allergic asthma include airway inflammation, increased numbers of eosinophils in BAL and sputum, and airways hyperresponsiveness. While the role of eosinoph | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $75,794 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement to R01 AI074074 was for acquisition of an item of equipment, a Li-COR Odyssey infrared imaging system. This allows accurate protein quantification of western immunoblots, and 'in-cell' or 'on-cell' westerns. This instrument | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| MISSOURI SYSTEM, UNIVERSITY OF | $50,304 | Grant | Trans-NIH Recovery Act Research Support: This is a proposal for a supplement to fund three undergraduate students to work in the lab during the summers of 2009 and 2010. These students will accelerate the tempo of the science while learning valuable laboratory procedures. Hopefully, they will | Health and Human Services, Department of / National Institutes of Health | 6/03/2009 |
| MISSOURI SYSTEM, UNIVERSITY OF | $256,512 | Grant | Trans-NIH Recovery Act Research Support: We request administrative supplement to hire new personnel and to purchase instrumentation that will accelerate the pace of the parent funded project (1R01-AI076119-01) and enhance the efficiency of the proposed research. The project focuses on characteri | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $27,467 | Grant | Trans-NIH Recovery Act Research Support: Funds were provided to hire and pay summer undergraduate researchers $8/hour for 40 hours/week to work in a research laboratory studying the pathogenesis of Giardia - a common waterborn parasite. | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | $74,000 | Grant | Trans-NIH Recovery Act Research Support: During its replication cycle in red blood cells, the human malaria parasite Plasmodium falciparum ingests and catabolizes up to 75% of the host cell's hemoglobin in an acidic degradative organelle called the food vacuole. Hemoglobin catabolism is required | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| HENRY FORD HEALTH SYSTEM | $401,576 | Grant | Trans-NIH Recovery Act Research Support: Inhaled corticosteroids (ICS) are considered first-line therapy for the management and control of patients with persistent asthma. Use of inhaled steroids has been associated with reduced airway responsiveness, improved lung function, diminished symptoms, | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | $313,745 | Grant | Trans-NIH Recovery Act Research Support: The thymus is the primary lymphoid organ responsible for the production of T cells, and its function is required for the generation of cellular immunity in vertebrates. The stromal cell types in the thymus form a complex meshwork of microenvironments thro | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF LOUISVILLE | $36,000 | Grant | Trans-NIH Recovery Act Research Support: This is an award for equipment to supplement with the prime research award program described by the award title. We have requested a sole-source purchase and are awaiting Dept. Purchasing approval. | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| UNIVERSITY OF ARKANSAS SYSTEM | $301,802 | Grant | Trans-NIH Recovery Act Research Support: Title: Physiological Factors in Hyperthermia. Description: The focus of the supplemental research will be to use our newly commissioned small animal conformal radiation research system (SACRRS) to apply simultaneous conformal radiation therapy and ther | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| THE CHILDRENS HOSPITAL LOS ANGELES | $397,563 | Grant | Trans-NIH Recovery Act Research Support: Although treatment has steadily improved in the past 20 years for children with high-risk metastatic neuroblastoma (stage 4), only 40% of these patients survive long-term. Our overall goal is to improve survival for these children. Problem: It is not pos | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF ARKANSAS SYSTEM | $129,874 | Grant | Trans-NIH Recovery Act Research Support: ARRA Admin Supp (NOT-OD-056) for 2R01 CA093897-05A1; Myeloma-Microenvironment Interaction Dynamics. Multiple myeloma, a malignancy characterized by accumulation of monoclonal plasma cells in the bone marrow, is associated with severe osteolytic bone disea | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF ARKANSAS SYSTEM | $368,216 | Grant | Trans-NIH Recovery Act Research Support: ARRA Admin Supp (NOT-OD-056) for RO1 CA134522-01, Potentiating Natural Killer Cell Anti-Myeloma Effects. Multiple myeloma, a malignancy of plasma cells, is a major health issue in the United States, with 100,000 people currently living with the disease a | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $71,193 | Grant | Trans-NIH Recovery Act Research Support: Administrative supplement to an active NIH Research Grant entitled Molecular Determinants of Oral Tongue Cancer Metastasis This is an application requesting administrative supplement, for equipment, to an active NIH Research Grant entitled Molecular Deter | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| UNIVERSITY OF ARKANSAS SYSTEM | $29,969 | Grant | Trans-NIH Recovery Act Research Support: Behavioral Treatment of Adolescent Marijuana Use. Marijuana remains the most prevalent illicit substance used by adolescents and the number of adolescents receiving treatment for marijuana abuse more than tripled during the last decade. A number of clinic | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| UNIVERSITY OF ARKANSAS SYSTEM | $367,091 | Grant | Trans-NIH Recovery Act Research Support: Reducing Sexual Risk Behaviors among Rural African-American Cocaine Users. This project will utilize a grounded theory approach to conduct a developmental formative evaluation to examine the local characteristics of organizations, providers, and potentia | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| YALE UNIVERSITY | $248,250 | Grant | Trans-NIH Recovery Act Research Support: This Competitive Revision of my currently funded RO1 (DE DE012459-12) is submitted in response to, and in accordance with Notice Number NOT-OD-09-058, titled, NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. One | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF NEBRASKA | $98,780 | Grant | Trans-NIH Recovery Act Research Support: The renal preglomerular microvasculature is critically involved in achieving the homeostatic functions of the kidneys, including the regulation of Na+ and H2O excretion. The primary Na+ retaining hormone, angiotensin II (AngII), acts via AT1 receptors (AT | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $306,490 | Grant | Trans-NIH Recovery Act Research Support: Studies will exploit the power of Drosophila genetics and the relative ease of administering toxins to flies to determine how genes and the environment may interact to promote the death of dopaminergic neurons and to inhibit the function of mitochondria. | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $730,926 | Grant | Trans-NIH Recovery Act Research Support: The objective of the NIH Grant Number R01EY009859 is to identify the genetic basis of age-related Maculopathy (GARM). This project is committed to the prospective study of genetic, environmental and early clinical risk factors for the development of macul | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF NEBRASKA | $90,082 | Grant | Trans-NIH Recovery Act Research Support: Funds were provided to purchase a specialized microscope (total internal reflectance microscope) that will be used to visualize the movements of single molecules or single synaptic vesicles. We will use this microscope to analyze the mechanisms used by p | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| YALE UNIVERSITY | $254,118 | Grant | Trans-NIH Recovery Act Research Support: PROJECT SUMMARY: Proper functioning of the cell cycle and its regulation in response to both internal and external stimuli is essential for the normal growth, division, and differentiation of cells and tissues. Major control over cell cycle progression is | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $57,000 | Grant | Trans-NIH Recovery Act Research Support: Myxococcus xanthus is an established model bacterium and hallmark for microbial social behaviors, which has provided valuable information about socio-microbiology for decades. Our laboratory has been supported by NIGMS for the past 12 years to study the | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF MASSACHUSETTS | $182,462 | Grant | Trans-NIH Recovery Act Research Support: To understand normal development and differentiation, it is necessary to determine the mechanisms by which cells initiate new programs of gene expression and promote formation of specific cell lineages. Typically, this involves activation of genes that a | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| NORTH CAROLINA STATE UNIVERSITY | $178,767 | Grant | Trans-NIH Recovery Act Research Support: This is a request to NIH for a Recovery Act Administrative Supplement to accelerate the tempo of research currently supported by 5R01GM056766-08, which is titled Computer Simulations of Protein Aggregation. The supplement would be used to hire an addit | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE | $104,260 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of the project is to characterize the structures and interactions of the BCL-2 family proteins, the principal regulators of the mitochondrion-dependent pathway for programmed cell death or apoptosis. Their opposing pro- or anti-apoptotic | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| THOMAS JEFFERSON UNIVERSITY | $128,189 | Grant | Trans-NIH Recovery Act Research Support: Signaling through the RAF-MEK-ERK1/2 MAP kinase pathway is critical for a wide variety of biological processes in both normal and disease states. Our long term goal is to determine mechanisms underlying regulation of this pathway and identify the downstre | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE | $96,379 | Grant | Trans-NIH Recovery Act Research Support: Toll-like receptors (TLRs) are the key sensors of microbes in innate immune cells. TLR activation is central for host defense; nevertheless dysregulation of TLR activation might lead to acute or chronic inflammatory diseases. Thus, the extent and duration | Health and Human Services, Department of / National Institutes of Health | 7/30/2009 |
| UNIVERSITY OF KANSAS CENTER FOR RESEARCH, INC. | $303,150 | Grant | Trans-NIH Recovery Act Research Support: Human cytochrome P450 (CYPs) are essential enzymes involved in clearing drugs and foreign chemicals from the body. The last decade of cytochrome P450 research suggests that many P450 proteins undergo induced fit in response to ligand binding and that liga | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF MASSACHUSETTS | $501,097 | Grant | Trans-NIH Recovery Act Research Support: Our overall goal is to identify transcription factors (TFs) that can bind C. elegans gene promoters. This will further our understanding of the networks that control gene expression and to delineate the regulatory genomic code. In the first year of the Pr | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF MASSACHUSETTS | $257,193 | Grant | Trans-NIH Recovery Act Research Support: Hsp90 is a unique chaperone that is essential in eukaryotes and that helps to produce and maintain the active state of a select set of biologically and medically important substrates/clients including many signal transduction proteins. Through these clien | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| YALE UNIVERSITY | $155,502 | Grant | Trans-NIH Recovery Act Research Support: Interventions to promote continued abstinence and the avoidance of risky sexual behaviors are far more likely to be successful than attempts to alter established patterns of high-risk sexual activity. The proposed project is a randomized, controlled trial | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $116,268 | Grant | Trans-NIH Recovery Act Research Support: This focus of this award is two-fold. First, funds will be used to support the salary of a postdoctoral fellow, who will help to coordinate the experiments described in the proposal. Second, funds will be used to purchase two new eye trackers for the lab. | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| YALE UNIVERSITY | $349,258 | Grant | Trans-NIH Recovery Act Research Support: Alveolar destruction and pulmonary fibrosis are juxtaposed in COPD and pulmonary fibrosis. Surprisingly, the relationships between these responses and the mechanisms that destroy alveoli while simultaneously nducing fibrosis have not been defined. Transfo | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $226,608 | Grant | Trans-NIH Recovery Act Research Support: Non-receptor tyrosine kinases have been implicated in protection of the ischemic myocardium, but the intracellular sites of action, and the molecular identity of the specific tyrosine kinases responsible for the effects attributed to pharmacologic inhibit | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| JOSLIN DIABETES CENTER, INC. | $198,604 | Grant | Trans-NIH Recovery Act Research Support: Control of HSC proliferation and migration by the transcription factor EGR1 - EGR1 (Early Growth Response 1) is a well-known transcription factor of the immediate early gene family. My lab recently discovered an unexpected and intriguing role for EGR1 in | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| UNIVERSITY OF ARKANSAS SYSTEM | $28,670 | Grant | Trans-NIH Recovery Act Research Support: Title - Telemedicine-Based Collaborative Care to Reduce Rural Health Disparities Description - To interpret the estimated relative effectiveness of the two models of collaborative care, it is necessary to know how well the care manager protocols were | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| YALE UNIVERSITY | $303,329 | Grant | Trans-NIH Recovery Act Research Support: Stroke is a major cause of morbidity and mortality in the United States and presents challenges in the development of disease prevention strategies. Deprivation of nutrients and oxygen supply to brain cells produces immediate death in the most severely af | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| YALE UNIVERSITY | $120,049 | Grant | Trans-NIH Recovery Act Research Support: Glutamate-receptor ion channels (iGluRs) participate in brain functions that range from fast synaptic transmission to activity-dependent changes that underlie certain forms of learning and memory. These receptors are also implicated in a variety of excito | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| YALE UNIVERSITY | $529,918 | Grant | Trans-NIH Recovery Act Research Support: The proper function of axons, the output of neurons, is critical to the proper functioning of the brain, particularly the cerebral cortex. Numerous neurological disorders result from disruption of axonal function. Our study will use newly developed and st | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $49,103 | Grant | Trans-NIH Recovery Act Research Support: The ARRA Summer Supplement grant was awarded to hire medical, undergraduate and high school students to perform research directly related to the parent R01 NS38992 grant. Three students were identified to be recipients of this award: Snow T. Nguyen, 1st | Health and Human Services, Department of / National Institutes of Health | 7/21/2009 |
| YALE UNIVERSITY | $960,956 | Grant | Trans-NIH Recovery Act Research Support: This country lacks a cohesive, informative surveillance system for vascular disease that can provide insights into national patterns of stroke and reveal national trends over time. Stroke is a major public health problem in the United States. It is the th | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE | $109,997 | Grant | Trans-NIH Recovery Act Research Support: This ARRA administrative supplement will fund pre-clinical work that will lead up to a human clinical trial for HIV-associated cognitive decline testing the peptide cytokines erythropoietin in conjunction with insulin-like growth factor-I. We have previo | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $72,406 | Grant | Trans-NIH Recovery Act Research Support: To determine how fl-mhtt expression in CPNs may influence cell autonomous gene expression in the cortex and non-cell-autonomous gene expression in the striatum, we will profile cortical and striatal gene expression from BACHD, BE, and WT control mice (N=4 | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF NEBRASKA | $144,460 | Grant | Trans-NIH Recovery Act Research Support: Neural progenitor cells (NPC) are present throughout life and replenish neurons and glia (astrocytes and oligodendrocytes) through neurogenesis, a process that requires proper migration, proliferation and differentiation of NPC. Neurogenesis appears to be | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| UNIVERSITY OF MASSACHUSETTS | $283,291 | Grant | Trans-NIH Recovery Act Research Support: This award is designed to investigate the role of protein kinase C epsilon (PKCe) in the antiadrenergic action of adenosine. The antiadrenergic action of adenosine via adenosine A1 receptors limits the responsiveness of the heart to beta-adrenergic nerv | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $258,762 | Grant | Trans-NIH Recovery Act Research Support: The goal of our studies is to determine the functional role of Runx2 expressed by vascular smooth muscle cells in regulating vascular calcification. In the parent grant, we have designed complementary studies using cultured vascular smooth muscle cells in | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $19,096 | Grant | Trans-NIH Recovery Act Research Support: This is an application requesting administrative supplement grant to support summer student research. In the parent award entitled Serum Proteome Analysis of Oral Cancer Metastasis (R21CA122806), we proposed to disover and validate serum protein biomarker | Health and Human Services, Department of / National Institutes of Health | 6/02/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $112,400 | Grant | Trans-NIH Recovery Act Research Support: The $80,000 administrative supplement to accelerate work on two specfic taskd required to achieve Specific Aim 2 of our original grant request: 1. to create image processing software for automated analysis of AFM images and 2. to implement modified AFM im | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF TENNESSEE | $181,903 | Grant | Trans-NIH Recovery Act Research Support: In order to continue to enhance and expand our goal of introducing authentic problem based learning into K- 12 schools, the NCRR SEPA Building Bridges to Health Science Literacy (BBHSl) program at the University of Tennessee Health Science Center will (1) | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| YALE UNIVERSITY | $35,847 | Grant | Trans-NIH Recovery Act Research Support: Support is requested for three undergraduate students and a high school science teacher to participate in summer research projects on one of the principal themes of the parent grant, namely the role of SLC26A6 and related transporters in the integrative p | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| MEDIOMICS, LLC | $63,366 | Grant | Trans-NIH Recovery Act Research Support: Mediomics is requesting funds to purchase a new fluorescence plate reader with the capability of performing time-resolved flourescence experiments. With this new instrument, we will be able to transfer the technology co-developed in Dr. Heyduk's laborato | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| DAEDALUS INNOVATIONS, LLC | $136,948 | Grant | Trans-NIH Recovery Act Research Support: Biomedical research continues to expand the use of detailed atomic-scale structure in developing a detailed understanding of the molecular basis for life and for disease. Tools for the identification of means for intervention at the molecular level are of | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF ARKANSAS SYSTEM | $389,046 | Grant | Trans-NIH Recovery Act Research Support: HCV NS3 and NS5A: Biochemical Mechanisms and Biological Functions; The long-term goal of this project is to determine the mechanism of RNA replication of HCV. The immediate focus of this proposal is on those proteins that bind and manipulate HCV RNA. N | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $94,943 | Grant | Trans-NIH Recovery Act Research Support: This supplement requests support for an additional method, molecular electron microscopy (EM), to be included in the studies involving all three aims of the prime. | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| CALIFORNIA STATE UNIVERSITY AUXILIARY SERVICES, INC | $106,194 | Grant | Trans-NIH Recovery Act Research Support: The timeline for finishing the construction of the entire 250 antisense clones in E. coli is the middle of funding period 3 (Y3), while the timeline for completely developing the target identification assay is by the middle of funding period 4 (Y4). Witho | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $478,597 | Grant | Trans-NIH Recovery Act Research Support: Medical Imaging Informatics Training Program- Administrative Supplement for additional trainee slots. The purpose of this administrative supplement is to request the restoration of several pre- and post-doctoral slots to the UCLA Medical Imaging Informati | Health and Human Services, Department of / National Institutes of Health | 7/23/2009 |
| SOCIAL & SCIENTIFIC SYSTEMS, INC. | $255,702 | Grant | Trans-NIH Recovery Act Research Support: The funds will be used to complete the HLA-typing of DNA specimens obtained from children participating in Pediatric AIDS Clinical Trials Group / International Maternal Pediatric Adolescent AIDS Clinical Trials Group protocols which will provide data to d | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| RESEARCH FOUNDATION FOR MENTAL HYGIENE INC | $761,047 | Grant | Trans-NIH Recovery Act Research Support: This application will use PET radioligand imaging, which is the only modality currently available to investigate the neurochemistry of cocaine addiction in the human brain in vivo. The advantage of this methodology is that it allows the more direct transl | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $656,340 | Grant | Trans-NIH Recovery Act Research Support: Primary hyperoxaluria type I (PH1) is an autosomal recessive disease caused by excessive oxalate production by hepatocytes due to peroxisomal alanineglyoxylate aminotransferase (AGT) deficiency, leading to increased conversion of glyoxylate to oxalate. In | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $755,380 | Grant | Trans-NIH Recovery Act Research Support: Work done in many laboratories has demonstrated that Ag stimulation of naive CD8 T cells can lead to different outcomes: development into effector cells and/or memory cells after immunogenic stimulation, and either activation and deletion or anergy in rel | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| CASE WESTERN RESERVE UNIVERSITY | $551,988 | Grant | Trans-NIH Recovery Act Research Support: Mutations in a series of ppGalNAc glycosyltransferases (protein glycosylating enzymes) have recently been found in patients with colon cancer. In this work we will study the enzymatic and biological properties of a series of mutant and wild type ppGalNA | Health and Human Services, Department of / National Institutes of Health | 4/28/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $537,962 | Grant | Trans-NIH Recovery Act Research Support: Role of hsnf5/BAF47 Loss in Human Cancer Development - ARRA The identification of tumor suppressor genes has led to new insights into the mechanisms of human cancer development. The normal functions of these genes often lie in the control of gene expres | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| COLORADO STATE UNIVERSITY | $500,358 | Grant | Trans-NIH Recovery Act Research Support: Oncogenesis occurs when mechanisms of cell growth control are deregulated. This generally develops in a multistep process that involves mutations in oncogenes and tumor suppressor genes. The understanding of this process has been greatly enhanced through | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO | $711,344 | Grant | Trans-NIH Recovery Act Research Support: Kaposi's sarcoma-associated herpesvirus (KSHV) is causally associated with Kaposi's sarcoma (KS) and several other AIDS-related malignancies. The long-term goal of this project is to apply effective KSHV genetic and infection systems to delineate the mole | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $862,283 | Grant | Trans-NIH Recovery Act Research Support: This is a competing renewal application for an interdisciplinary project to develop novel multifunctional tumor targeted proapoptotic anticancer drug delivery systems (DDS) to enhance the efficiency of treatment of multidrug resistant (MDR) ovarian primar | Health and Human Services, Department of / National Institutes of Health | 7/31/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE | $509,388 | Grant | Trans-NIH Recovery Act Research Support: Etiology of Translocations in Hematopoietic Cells The long-term objective of my research is to understand the influence of hematopoietic-specific developmental programs on the repair DNA damage such as double strand breaks (DSBs) and the initial molecula | Health and Human Services, Department of / National Institutes of Health | 6/19/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $565,788 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this award is to 1) define the repression mechanism of E2-Brd4 in HPV Chromatin and 2) to define the role of E2-P.85 in HPV Chromatin Transcription. We will explore this possibility using our in vitro-reconstituted HPV chromatin transcri | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| UNIVERSITY OF PITTSBURGH THE | $536,687 | Grant | Trans-NIH Recovery Act Research Support: It is estimated that over 500,000 persons across the world will die this year from hepatocellular carcinoma (HCC). HCC is a major health problem, particularly in underdeveloped countries, and poses a series of complex health management issues. Elucidati | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $672,615 | Grant | Trans-NIH Recovery Act Research Support: In the intestinal tract, the first line of defense against pathogenic microorganisms is the layer of epithelial cells that line its extensive mucosal surface. These cells provide a physical barrier to infection & play critical roles at mucosal immune site | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $106,259 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this award is to establish a conditional GDNF knockout mouse colony at MUSC which will substantially expand and accelerate the current research associated with the aims of the parent grant PO1 AG023630. | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $248,111 | Grant | Trans-NIH Recovery Act Research Support: DNA Damage and Neurodegeneration in the Aging Brain. The supplement will satisfy the main goals of the Recovery Act by employing a researcher and accelerating new research with the potential to uncover new insights into mechanisms of and treatments for ne | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $262,705 | Grant | Trans-NIH Recovery Act Research Support: This application proposes a three-year renewal of a KOI International Research Scientist Career Development Award focused on characterizing T-cell immune responses to Vibrio cholerae infection. The program will be conducted under the collaborative mentors | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $1,830,483 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION 3 OVERALL PROGRAM CRITIQUE 3 PROGRESS DURING THE CURRENT FUNDING PERIOD 4 PROGRAM LEADERSHIP 5 PROGRAM AS AN INTEGRATED EFFORT 5 PROJECT AND CORE SUMMARIES OF DISCUSSION 6 BUDGETARY OVERLAP 8 COLLABORATING INSTITUTIONS 8 INDIVIDUAL PROJECTS AN | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $891,083 | Grant | Trans-NIH Recovery Act Research Support: In this two-year AARA grant application, we propose to continue our investigation into 4D image reconstruction methods to further improve the quality and quantitative accuracy of 4D gated myocardial perfusion (GMP) emission computed tomography (ECT) inclu | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| WASHINGTON UNIVERSITY, THE | $879,098 | Grant | Trans-NIH Recovery Act Research Support: Atherosclerotic coronary artery disease is the largest single killer of Americans and the most complex subset of these patients have decreased heart function because of the blockage in their coronary arteries. Coronary bypass surgery and coronary stentin | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $803,250 | Grant | Trans-NIH Recovery Act Research Support: Alterations in cardiac lipid metabolism are associated with heart failure in patients with diabetes and obesity. Excess dietary fat is also thought to be deleterious. Fatty acids (FAs) and glucose supply energy to all tissues of the body, however, the hea | Health and Human Services, Department of / National Institutes of Health | 7/31/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $810,001 | Grant | Trans-NIH Recovery Act Research Support: It is clear that the tissue microenvironment plays a critical role in regulating inflammation and tissue destruction. Chronic inflammation and tissue fibrosis lead not only to increased turnover of the extracellular matrix but also to an increase in infla | Health and Human Services, Department of / National Institutes of Health | 5/30/2009 |
| UNIVERSITY OF ILLINOIS | $1,120,202 | Grant | Trans-NIH Recovery Act Research Support: The mechanisms regulating acute inflammation with severe sepsis need to be better defined to design treatments that can be used to protect the lungs and prevent death from multiple organ failure. Pulmonary macrophages are immune-effector cells that, at le | Health and Human Services, Department of / National Institutes of Health | 5/30/2009 |
| FLORIDA INSTITUTE OF TECHNOLOGY, INC. | $831,521 | Grant | Trans-NIH Recovery Act Research Support: 5-Oxo-ETE has the qualifications of an important physiological mediator: It is formed by a highly selective enzyme 5-hydroxyeicosanoid dehydrogenase (5-HEDH). Its actions are mediated by the selective OXE receptor (OXE-R), and metabolism by various pathwa | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF PITTSBURGH THE | $1,901,894 | Grant | Trans-NIH Recovery Act Research Support: In previous work, we have developed, deployed and evaluated a novel intelligent medical training system for pathologic diagnosis and reporting. SlideTutor is an individualized, adaptive, simulation environment that provides explanations and assistance spe | Health and Human Services, Department of / National Institutes of Health | 5/27/2009 |
| UNIVERSITY OF THE SCIENCES IN PHILADELPHIA | $211,159 | Grant | Trans-NIH Recovery Act Research Support: The 2,4-thiazolidinedione (TZD) ring is found in currently marketed and investigational therapeutic agents. This is a potential human health concern since hepatotoxicity was reported in some patients taking TZD ring containing drugs. An example of this is | Health and Human Services, Department of / National Institutes of Health | 5/13/2009 |
| WAKE FOREST UNIVERSITY | $531,010 | Grant | Trans-NIH Recovery Act Research Support: Our society must make difficult policy decisions about complex biomedical research and treatment issues without the scientific understanding or expertise to critically evaluate these issues. So, while scientists understanding of the effects of addictive d | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| ENDACEA, INC | $1,069,972 | Grant | Trans-NIH Recovery Act Research Support: Despite the availability of newer antimicrobial agents, improved supportive care, and the introduction of an FDA approved adjunctive therapy for sepsis, (Xigris(r), drotrecogin alfa), the mortality rate for severe sepsis and septic shock of 30-60% remains | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| SOYMEDS INC | $877,379 | Grant | Trans-NIH Recovery Act Research Support: A Novel Therapy for Staphylococcal Enterotoxin B Poisoning is a research grant aimed at developing a soy-based vaccine for Enterotoxin B Poisoning, which is a potential weapon of bioterrorism. Currently, no effective vaccine exists that provides protectio | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| MATTEK CORPORATION | $871,183 | Grant | Trans-NIH Recovery Act Research Support: Psoriasis is a chronic, inflammatory, hyper-proliferative skin disease that affects nearly 80 million people worldwide. During Phase 1, cells from involved psoriatic lesions were harvested, proliferated in monolayer culture, and cryopreserved. Culture con | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| VISTA SCIENTIFIC LLC | $1,604,601 | Grant | Trans-NIH Recovery Act Research Support: Title: Ocular Insert for Non-Invasive Sustained Drug Delivery for the Treatment of Glaucoma. Through Phase I and Phase II SBIR Grant Awards, Vista Scientific has developed and combined two unique drug delivery technologies that can resolve several ophth | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| RUSH UNIVERSITY MEDICAL CENTER | $8,038,504 | Grant | Trans-NIH Recovery Act Research Support: The major goals of this project are to identify risk factors for incident Alzheimer's disease in a biracial community and to estimate prevalence and incidence of Alzheimer's disease in this community. | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF MEDICINE AND DENTISTRY OF NJ (INC) | $810,720 | Grant | Trans-NIH Recovery Act Research Support: Trypanosome-related disease is responsible for significant devastation of productive human lives and high mortality rates throughout the world. The trypanosome transcriptional machinery appears to exhibit intriguing differences from the more conserved ma | Health and Human Services, Department of / National Institutes of Health | 9/26/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $728,684 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Helicobacter pylori remains the most prevalent infectious disease in the world, with up to100% of people colonized in some populations. Disease due to H. pylori is variable, however: only a minority of infected individ | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $630,000 | Grant | Trans-NIH Recovery Act Research Support: Hepatitis C virus (HCV) is an important human pathogen with a high rate of persistence that can lead to liver cirrhosis and cancer. Given the relevance of T cells in HCV pathogenesis and emerging literature on immune function and exhaustion, we hypothesiz | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| UNIVERSITY OF MEDICINE AND DENTISTRY OF NJ (INC) | $780,000 | Grant | Trans-NIH Recovery Act Research Support: Toxoplasma is a major opportunistic parasitic infectious agent in man and animals. Disease can result from a weak immune response resulting in parasite lysis of host tissue or it can ensue following an inappropriate immune response, leading to immunopatho | Health and Human Services, Department of / National Institutes of Health | 5/06/2009 |
| UNIVERSITY OF TEXAS M D ANDERSON | $693,000 | Grant | Trans-NIH Recovery Act Research Support: Innate immunity plays a crucial role in initiating the immune responses and pathogen clearance upon microbial infection. Using pattern recognition receptors including cell surface receptor such as Toll-like receptors (TLRs) or intracellular receptors such | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| DUKE UNIVERSITY | $614,162 | Grant | Trans-NIH Recovery Act Research Support: Interleukin 7 (IL-7) has been demonstrated to provide signals via the IL-7 receptor which are required at many stages of lymphocyte development. IL-7 receptor is composed of two different cytokine receptor subunits; the IL-7 receptor alpha chain and the c | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | $748,268 | Grant | Trans-NIH Recovery Act Research Support: We will investigate the roles of co-stimulatory molecules and soluble mediators in LNFPIII induced immune suppression. We will perform studies to determine how the immunomodulatory glycan LNFPIII activates antigen presenting cells, focusing on binding to | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $558,617 | Grant | Trans-NIH Recovery Act Research Support: Infections caused by Staphylococcus aureus span a wide clinical spectrum, ranging from asymptomatic nasal carriage to endocarditis, bone and joint infections and lethal shock. Increasing rates of S. aureus infection and the emergence of community-acquired | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF CINCINNATI | $711,483 | Grant | Trans-NIH Recovery Act Research Support: Systemic lupus erythematosus (SLE) is an autoimmune disease. The disease develops at a female-to-male ratio of 10:1. Although, several factors, such as gene polymorphisms, female sex hormone estrogen, and interferon-signaling, are implicated in gender bia | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| LOMA LINDA VETERANS ASSOCIATION FOR RESEARCH AND EDUCATION | $616,520 | Grant | Trans-NIH Recovery Act Research Support: The amount of bone formed early in childhood is a very important determining factor in terms of whether or not the individual will develop osteoporosis later in life. Therefore, it is great importance to understand the molecular mechanisms that contribut | Health and Human Services, Department of / National Institutes of Health | 8/07/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE | $1,413,303 | Grant | Trans-NIH Recovery Act Research Support: Food allergy is a growing and serious health concern in the United States. There is no definitive treatment for PN or other food allergies. In our initial R01 grant project, we developed Food Allergy Herbal Formula-2 (FAHF-2) and showed that it completely | Health and Human Services, Department of / National Institutes of Health | 6/29/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $734,740 | Grant | Trans-NIH Recovery Act Research Support: This project is being supported with funds from the American Recovery and Reinvestment Act, which may involve a reduction in the research aims and scope. If necessary, a revised abstract will be posted soon and this notice removed. DESCRIPTION (provided | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| THE VANDERBILT UNIVERSITY | $858,191 | Grant | Trans-NIH Recovery Act Research Support: For metastatic prostate cancer (PCa), androgen deprivation therapy results in regression of the metastatic disease and a dramatic decrease in the serum of the androgen dependent prostate-specific antigen (PSA) protein. Eventually, all patients will fail t | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $638,636 | Grant | Trans-NIH Recovery Act Research Support: This project is being supported with funds from the American Recovery and Reinvestment Act, which may involve a reduction in the research aims and scope. If necessary, a revised abstract will be posted soon and this notice removed. DESCRIPTION (provided | Health and Human Services, Department of / National Institutes of Health | 5/13/2009 |
| MAYO CLINIC | $767,689 | Grant | Trans-NIH Recovery Act Research Support: Studies are currently underway to examine the genetic factors contributing to a range of addictions, including critical public health problems like smoking and alcohol abuse. New approaches use emerging technologies-such as genome-wide association studies | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| ERNEST GALLO CLINIC AND RESEARCH CENTER | $654,400 | Grant | Trans-NIH Recovery Act Research Support: Trafficking and signaling of opioid receptor subtypes and hetrodimers This proposal is focused on how receptor pharmacology and trafficking are altered by co-expression/heterodimerization of the opioid receptors with a focus on heterodimers containing th | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $996,973 | Grant | Trans-NIH Recovery Act Research Support: Psychostimulants such as methylphenidate and amphetamine have become drugs of choice for the treatment of attention deficit hyperactivity disorder (ADHD). Along with falling prices for recreational stimulants like powder cocaine, stimulants are increasing | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| TREATMENT RESEARCH INSTITUTE | $1,187,275 | Grant | Trans-NIH Recovery Act Research Support: This two-year NIDA R01 competing-continuation grant extended the work of Dr. Festinger and TRIG??s section on Law & Ethics on improving the ethics of informed consent to participate in research studies. The initial 3-year grant examined the effects of a | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| BAYLOR COLLEGE OF MEDICINE | $690,750 | Grant | Trans-NIH Recovery Act Research Support: 'Main goal: Understand the molecular mechanisms that govern the nicotine withdrawal syndrome. Abstract. Nicotine addiction is a major worldwide medical and social problem that continues to escalate. Affective and somatic symptoms associated with nicotine | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $1,430,665 | Grant | Trans-NIH Recovery Act Research Support: The goal of our research is to bridge the gap between basic research in cochlear physiology and clinical tools in otology such as otoacoustic emissions and cochlear implants. We will use a combination of experimental and theoretical techniques to develop | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $1,482,589 | Grant | Trans-NIH Recovery Act Research Support: The major intent of this project is to modify and expand a family weight gain prevention program that has previously been shown to be effective. Our previous America On the Move (AOM) Family Program, which focused on helping families make small changes in | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $861,032 | Grant | Trans-NIH Recovery Act Research Support: The long-term objectives of our research are to develop a mechanistic understanding of how cell-cell and cell-extracellular matrix adhesive interactions regulate erythropoiesis. Erythroblasts differentiate in erythroblast islands, composed of erythroblast | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UTAH STATE UNIVERSITY | $694,349 | Grant | Trans-NIH Recovery Act Research Support: The incidence of obesity worldwide continues to escalate with the spread of the Western diet and with it there has been a corresponding increase in cardiovascular disease, diabetes, end-stage renal disease and other obesity-related disorders. Of all the c | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $695,253 | Grant | Trans-NIH Recovery Act Research Support: This competitive renewal continues to focus on the regulation of TGF-beta and Bmp7 in chronic and acute renal disease. Given that TGF-beta promotes renal interstitial fibrosis, whereas Bmp7 is thought to protect against this effect, the potential for deve | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| SAINT LOUIS UNIVERSITY | $643,632 | Grant | Trans-NIH Recovery Act Research Support: Congenital anomalies affecting the kidney and urinary tract are among the most common serious birth defects. While there is significant clinical and increasing genetic data on these disorders, the disease mechanisms are not well understood. The proposed s | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF UTAH, THE | $747,241 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The urinary tract is normally a sterile environment, kept free of microbes by the flow of urine and by myriad anti-microbial molecules and effector immune cells. However, despite these formidable host defenses and the | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| NORTHWESTERN UNIVERSITY | $660,848 | Grant | Trans-NIH Recovery Act Research Support: Laser scanning microscopy (LSM), including confocal and 2-photon microscopy, continues to play a central role in many areas of biomedical research. In neuroscience alone, the number of applications continues to grow rapidly. However, in contrast to the on | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| UNIVERSITY OF MARYLAND | $750,886 | Grant | Trans-NIH Recovery Act Research Support: This is a competing renewal application. The overall thrust of the project is to develop novel fluorescent sensing and imaging technology for understanding the biology of zinc, with a view to developing novel and improved diagnostics and therapies for hum | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| UNIVERSITY OF WASHINGTON | $1,047,984 | Grant | Trans-NIH Recovery Act Research Support: The long-term objective of this research is to understand how the brain translates sensory information into the commands for movements. The oculomotor system is an excellent model for study because of its simple peripheral mechanics and musculature and th | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| TRUSTEES OF TUFTS COLLEGE INC | $999,948 | Grant | Trans-NIH Recovery Act Research Support: Inflammatory diseases of the lacrimal gland such as Sj+?grenG??s syndrome, sarcoidosis, and chronic graft versus-host disease or simply as occurs with advanced age, lead to inadequate secretion of the aqueous layer of the tear film, which is a leading cau | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $739,032 | Grant | Trans-NIH Recovery Act Research Support: This application is in response to potential support for two years as part of the American Recovery and Reinvestment Act of 2009. The Specific Aims have been modified from the original proposal to fit 2 years of funding. The proteasome complex plays a fun | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| THE JACKSON LABORATORY | $870,000 | Grant | Trans-NIH Recovery Act Research Support: The objectives of this competing renewal are to identify and characterize craniofacial (CF) disorders in mice that are reliable genetic and physiological models for human craniofacial dysmorphologies and to share these models with the scientific public. D | Health and Human Services, Department of / National Institutes of Health | 6/03/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $782,937 | Grant | Trans-NIH Recovery Act Research Support: Neurons in the retina make remarkably precise connections with their synaptic targets. Indeed, such precision is a hallmark of neuronal connectivity in many parts of the brain. These connections define the wiring diagram of the nervous system, and are cri | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $622,948 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The cytochromes P450 are a ubiquitous superfamily of mixed function oxidases responsible for the oxidation of a vast number of compounds including the majority of drugs used by humans. In the course of our studies to d | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $1,475,945 | Grant | Trans-NIH Recovery Act Research Support: This work develops and applies new advanced methods of imaging, or 'seeing', the structures of proteins and how they work, very much in the spirit of the development of, for example, magnetic resonance imaging methods developed in the last century. The fr | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $1,376,002 | Grant | Trans-NIH Recovery Act Research Support: This ARRA application represents an extension of RO1-44351, the first prospective cohort investigation of children with new onset epilepsy designed to characterize the etiology and natural history of neurodevelopmental abnormalities in cognition, brain st | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $810,465 | Grant | Trans-NIH Recovery Act Research Support: Cyclooxygenase-2 (COX-2) is the inducible form of cyclooxygenase and catalyzes the rate- limiting step in the formation of prostaglandins from arachidonic acid. COX-2 expression and prostaglandin production increase markedly in neurons following a variety | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| WASHINGTON UNIVERSITY, THE | $756,632 | Grant | Trans-NIH Recovery Act Research Support: Hypoxic cell death in the form of stroke and myocardial infarction is the largest single cause of death in theUnited States. The fundamental molecular mechanisms of hypoxic cell death are incompletely understood.Studies in genetically tractable model orga | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $732,121 | Grant | Trans-NIH Recovery Act Research Support: We are studying the mechanism of the catalytic reaction that converts molecular nitrogen into ammonia by the bacterial enzyme nitrogenase. For the catalytically central iron-molybdenum cofactor duster in nitrogenase, we will examine geometric and electron | Health and Human Services, Department of / National Institutes of Health | 8/18/2009 |
| GEORGIA TECH RESEARCH CORPORATION | $571,028 | Grant | Trans-NIH Recovery Act Research Support: Long distance electron transfer plays an important role in biological function in many enzymes. In these reactions, radical transport may occur and may involve transfer of an electron alone (ET) or a proton coupled, electron transfer reaction (PET). The m | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $593,598 | Grant | Trans-NIH Recovery Act Research Support: A fundamental feature of a living system is the integrated network of biochemical pathways and processes that generate a balanced and robust metabolism. The long term goal of the research in my laboratory is to contribute to our understanding of the metab | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF WASHINGTON | $553,439 | Grant | Trans-NIH Recovery Act Research Support: The goal of this proposal is a molecular level description of protein unfolding, and by extension folding, using realistic molecular dynamics (MD) simulations in solution. Both the general and sequence-specific rules of unfolding will be pursued. The gene | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| RENSSELAER POLYTECHNIC INSTITUTE | $598,158 | Grant | Trans-NIH Recovery Act Research Support: The Protein-target interaction is one of the most important processes occurring in biological systems. One subgroup of such interactions takes place with a dramatic change in the secondary structure: from unstructured (coil) when it is unbound to a very c | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF CHICAGO, THE | $713,618 | Grant | Trans-NIH Recovery Act Research Support: Voltage-gated ion channels (VGC) are proteins found in the membranes of practically all cells and that through opening and closing (gating) events let ions flow through between the internal and external milieu of the cells acting as very fast signaling en | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $599,516 | Grant | Trans-NIH Recovery Act Research Support: Award Title: Developmental Control of Spindle Positioning in Embryos Description: The goal of the grant is to elucidate the molecular mechanisms that control the position of the mitotic spindle during development, using the nematode C. elegans as model sy | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $593,750 | Grant | Trans-NIH Recovery Act Research Support: The primary objective of this project is to understand the signaling mechanism of light activated sensory rhodopsins (SRs), part of the growing family of 7-helix transmembrane microbial rhodopsins. Examples of SRs include SRI and SRII from archaebacteria, | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $772,500 | Grant | Trans-NIH Recovery Act Research Support: The developmental mechanisms of human and Drosophila blood systems show remarkable parallels. Most genes essential for the formation and maturation of Drosophila hemocytes are conserved in humans and the majority is associated with hematopoietic malignanc | Health and Human Services, Department of / National Institutes of Health | 8/27/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $974,463 | Grant | Trans-NIH Recovery Act Research Support: The pituitary gland contains individualized cell types that specialize in the production of individual hormones. Understanding the mechanisms that underlie the transition from proliferation to cell differentiation is important because many body functions | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $770,000 | Grant | Trans-NIH Recovery Act Research Support: Totally blind people with no light perception cannot synchronize (entrain) their circadian rhythms to the light/dark cycle. Nevertheless, about half of these people are entrained to the 24- hour day. The time cues for entrainment are not known and may inc | Health and Human Services, Department of / National Institutes of Health | 8/26/2009 |
| GEORGETOWN UNIVERSITY (THE) | $849,458 | Grant | Trans-NIH Recovery Act Research Support: This competitive renewal application is to continue on going studies in mice aimed at our long held goal of generating knowledge that can be used to mitigate, and remediate, alveolar loss in individuals with chronic obstructive pulmonary disease (COPD). I | Health and Human Services, Department of / National Institutes of Health | 5/30/2009 |
| UNIVERSITY OF ILLINOIS | $785,000 | Grant | Trans-NIH Recovery Act Research Support: The Aims stem from our initial investigations of enzymes that metabolize peptides such as bradykinin (BK), angiotensins and others. Inhibitors of angiotensin I converting enzyme (kininase II; ACE) are currently used to treat millions of patients with hype | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| BETH ISRAEL DEACONESS MEDICAL CENTER INC | $1,413,062 | Grant | Trans-NIH Recovery Act Research Support: A detailed comprehension of the role of the thrombospondins (TSPs), including cartilage oligomeric matrix protein (COMP), in the regulation of extracellular matrix (ECM) structure and cellular behavior during tissue genesis and repair is the long-term goa | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| WAYNE STATE UNIVERSITY (INC) | $916,200 | Grant | Trans-NIH Recovery Act Research Support: This proposal is focused on the altered neuronal control of coronary blood flow and the impact on ventricular function during exercise in heart failure as well as the role of vasoconstriction in active skeletal muscle in mediating the exaggerated sympathe | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF TEXAS HEALTHCARE AT TYLER | $830,131 | Grant | Trans-NIH Recovery Act Research Support: The coagulation cascade is initiated by binding of the coagulation factor VII(a) (FVIIa) to its cell surface receptor, tissue factor (TF). An aberrant expression of TF is the primary reason for thrombotic disorders associated with various diseases. Proper | Health and Human Services, Department of / National Institutes of Health | 6/15/2009 |
| SRI INTERNATIONAL | $1,116,005 | Grant | Trans-NIH Recovery Act Research Support: Description (provided by applicant): The Two Process model of homeostatic sleep regulation posits that the timing of sleep is due to the interaction between a circadian process (Process C) and a homeostatically regulated sleep process (Process S). Whereas | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| GEORGIA HEALTH SCIENCES UNIVERSITY RESEARCH INSTITUTE, INC. | $718,550 | Grant | Trans-NIH Recovery Act Research Support: We previously reported that sodium excretion is significantly correlated to the excretion of nitrate/nitrite (metabolites of nitric oxide) in normotensive young adults. This association of the nitric oxide pathway with sodium excretion in humans led us to | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| UNIVERSITY OF WASHINGTON | $873,269 | Grant | Trans-NIH Recovery Act Research Support: Activation of the endothelial cells that line blood vessels during inflammatory processes such as those associated with cardiovascular disease results in the recruitment of circulating white blood cells into the vessel wall that can ultimately contribute | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| NORTHWESTERN UNIVERSITY | $885,485 | Grant | Trans-NIH Recovery Act Research Support: The proposed research is directed at the study of growth-associated protein GAP-43, an essential presynaptic protein with critical functions in neural development (axonal pathfinding), and plasticity (long-term potentiation, learning and memory). Because | Health and Human Services, Department of / National Institutes of Health | 5/26/2009 |
| WAYNE STATE UNIVERSITY (INC) | $760,000 | Grant | Trans-NIH Recovery Act Research Support: The goal of this award is to generate an inducible knockin mouse targeting the Plp1 gene on the X-chromosome. Mutations in the PLP1 gene cause Pelizaeus-Merzbacker disease, and we have determined that a major in the pathophysiology is a protein traffickin | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $805,521 | Grant | Trans-NIH Recovery Act Research Support: Many acid-base transporters contribute to intracellular and extracellular pH regulation in brain. Electrogenic Na/Bicarbonate Cotransporters (NBCs) are particularly important because they alter pH in response to neuronal activity. While the physiologic si | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| UNIVERSITY OF CHICAGO, THE | $780,000 | Grant | Trans-NIH Recovery Act Research Support: Muscle degeneration underlies many forms of muscular dystrophy and may also contribute significantlyto the decline of muscle mass associated with the normal aging process. Limb Girdle MuscularDystrophy 2B is a recessive form of muscular dystrophy that is | Health and Human Services, Department of / National Institutes of Health | 9/20/2009 |
| SALK INSTITUTE FOR BIOLOGICAL STUDIES | $473,500 | Grant | Trans-NIH Recovery Act Research Support: Our goal is to understand the induction of HIV-1 transcription by the viral Tat protein, and its connection to other steps needed to process viral mRNAs and facilitate their export out of the nucleus. The HIV-1 Tat protein works with the host cell P-TEFb | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| UNIVERSITY OF CHICAGO, THE | $390,000 | Grant | Trans-NIH Recovery Act Research Support: Nuclear factor-KB (NF-?B) is a transcription factor that plays many essential roles in immune responses in vivo, from contributing to the formation of lymph nodes and Peyer's patches to allowing generation and maturation of dendritic cells and controlling | Health and Human Services, Department of / National Institutes of Health | 6/18/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $803,870 | Grant | Trans-NIH Recovery Act Research Support: EAE is an inflammatory disease of the central nervous system initiated by myelin antigen-specific encephalitogenic CD4+ Th1 cells. After encountering antigen, T cells receive signal 1 through the TCR and signal 2 through positive costimulatory molecules l | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| COLORADO STATE UNIVERSITY | $324,264 | Grant | Trans-NIH Recovery Act Research Support: Poliovirus is the best-known member of a large family of viruses that have genomes made of RNA. These viruses carry a gene for a very specific RNA dependent RNA polymerase protein that is responsible for replicating the virus genome. The focus of this res | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $338,355 | Grant | Trans-NIH Recovery Act Research Support: Galactofuranose (Galf) residues have been implicated in the virulence or viability of many microbes, including mycobacteria. The goal of the proposed research is to understand the mechanisms underlying Galf residue incorporation into the mycobacterial cel | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| LOUISIANA STATE UNIVERSITY SYSTEM | $150,000 | Grant | Trans-NIH Recovery Act Research Support: Diabetes affects 24 million Americans, 220 million people worldwide, and is the 6th leading cause of death in the US. Diabetic nephropathy (DN) is the most common cause of kidney failure in the US. This chronic and debilitating disease is characterized by | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| OKLAHOMA MEDICAL RESEARCH FOUNDATION | $815,000 | Grant | Trans-NIH Recovery Act Research Support: Adenosine modulates many important physiological processes by triggering ubiquitously expressed adenosine receptors. This project is focused on ecto-5?-nucleotidase (CD73), a glycosyl phosphatidylinositol (GPI)-linked membrane protein that catalyzes the e | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| NORTHEASTERN UNIVERSITY | $786,157 | Grant | Trans-NIH Recovery Act Research Support: Engineering Biomimetic Corneal Constructs | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| BROWN UNIVERSITY IN PROVIDENCE IN STATE OF RI AND PROVIDENCE PLANTATIONS | $264,661 | Grant | Trans-NIH Recovery Act Research Support: The training grant Aging Health and Health Services Research addresses all 4 of the major goals of the NIA Strategic Plan for research, by educating well trained researchers, with multi-disciplinary experience and a broad understanding of the biological, | Health and Human Services, Department of / National Institutes of Health | 5/15/2009 |
| YALE UNIVERSITY | $39,746 | Grant | Trans-NIH Recovery Act Research Support: In cystic fibrosis (CF), mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel are associated with defective cAMP and acid-stimulated duodenal bicarbonate secretion, and defective cAMP and cGMP-activated fluid secret | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| LOUISIANA STATE UNIVERSITY SYSTEM | $29,929 | Grant | Trans-NIH Recovery Act Research Support: We hypothesize that deletion of GABAergic funciton of accumbens shell neurons will lead to constant disinhibition of target areas including the lateral hypothalamus, resultingin hyperphagia on palatable food and development of obesity. | Health and Human Services, Department of / National Institutes of Health | 6/22/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $54,000 | Grant | Trans-NIH Recovery Act Research Support: Because trials to compare digital and analog mammography rely on complex designs, cost large amounts of money and involve the health of many women, accurate power and sample size calculations are essential. In these trials, radiologists read many films us | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $98,275 | Grant | Trans-NIH Recovery Act Research Support: Colon Cancer Screening Decisions in Late Life - ARRA With the requested funds, we will be able to increase the value of the parent grantG??s findings by conducting additional analyses of unexpected findings from the parent grant and feeding these finding | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $99,999 | Grant | Trans-NIH Recovery Act Research Support: Risk factors for site-specific metastasis in esophageal cancer are poorly understood. As part of my current K07 award, we are currently enrolling patients to assemble a cohort of study subjects with newly diagnosed esophageal cancer. Based on prospectiv | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| FOX CHASE CANCER CENTER | $108,000 | Grant | Trans-NIH Recovery Act Research Support: Dr. Yu-Ning Wong, a Medical Oncologist at Fox Chase Cancer Center is dedicated to a career in cancer health services research. Her goal is to develop a multidisciplinary research program to understand the impact of insurance design on cancer drug utilizat | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $50,000 | Grant | Trans-NIH Recovery Act Research Support: HIV-1 infection is associated with loss of CD4+ T cells, chronic immune activation and progressive immune dysfunction. HIV-specific responses, particularly those of CD4+ T cells, become impaired early after infection and the basis for this decline in func | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| UNIVERSITY OF WASHINGTON | $49,951 | Grant | Trans-NIH Recovery Act Research Support: The PI of this grant is an M.D., Ph.D. who is committed to academic research and recently completed his clinical training in the Division of Infectious Disease at the University of Washington in Seattle. The proposal describes a 5 year training program d | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $108,000 | Grant | Trans-NIH Recovery Act Research Support: This proposal describes a five year career development plan for Soumya Raychaudhuri in statistical genetics. Dr. Raychaudhuri is a Rheumatology fellow at the Brigham and Women's Hospital (BWH). He will integrate his background in bioinformatics with the s | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| CASE WESTERN RESERVE UNIVERSITY | $108,000 | Grant | Trans-NIH Recovery Act Research Support: The proposed project will be performed in the areas of tyrosine kinases, cytoskeleton, and invasion/metastasis in SCLC. My long term career goal is to become an independent clinician-scientist in translational cancer research with focus on targeted therap | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF WASHINGTON | $97,260 | Grant | Trans-NIH Recovery Act Research Support: This application requests an administrative supplement for a mentored K-award (K08-CA128565) in accordance with the stated goals of the American Recovery and Reinvestment Act of 2009 (ARRA). The purpose of this administrative supplement will be to suppo | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| UNIVERSITY OF MASSACHUSETTS | $53,932 | Grant | Trans-NIH Recovery Act Research Support: This project seeks to create a new employment opportunity in an active NIA parent grant. The parent grant is a research scientist training award (1K01AG031836-01A1) with a potentially important and ambitious research program on cost-related nonadherence ( | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF NEBRASKA | $108,000 | Grant | Trans-NIH Recovery Act Research Support: Estrogen exposure correlates with a reduced risk of colorectal cancer (CRC). Nonetheless, little is known about the mechanisms through which estrogens protect against CRC. At least some of the effects of estrogens on CRC are likely mediated via the estrog | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| JOSLIN DIABETES CENTER, INC. | $107,314 | Grant | Trans-NIH Recovery Act Research Support: Adipocyte Insulin Signaling in Metabolism and Aging - This is a request for an administrative supplement to NIH grant 1 K08 AG032869-01 entitled G?Adipocyte Insulin Signaling in Metabolism and AgingG?. Permanently blocking the ability of insulin to act o | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| YALE UNIVERSITY | $107,982 | Grant | Trans-NIH Recovery Act Research Support: Project Summary Naturally occurring sequences capable of forming H-DNA (triplexes) are found in the human genome as frequently as 1 in every 50,000 base pairs. These sequences are typically found in promoters and exons and are believed to be involved in | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF ARKANSAS SYSTEM | $117,249 | Grant | Trans-NIH Recovery Act Research Support: Rural areas are often medically underserved and represent about 20% of the U.S. population. Telemedicine holds considerable promise in alleviating many constraints imposed by time and distance on subspecialty health care encounters. As a consequence, se | Health and Human Services, Department of / National Institutes of Health | 8/29/2009 |
| UNIVERSITY OF ARKANSAS SYSTEM | $609,098 | Grant | Trans-NIH Recovery Act Research Support: Center for Translational Neuroscience TELEMEDICINE (COBRE). This is a supplement for the development of an Emergency Department Physicians Learning and Collaborative Education program, linking 5 emergency departments with the academic institution via tele | Health and Human Services, Department of / National Institutes of Health | 9/08/2009 |
| UNIVERSITY OF NEBRASKA | $242,673 | Grant | Trans-NIH Recovery Act Research Support: The UNMC Eppley Cancer Center is an NCI-designated matrix Clinical Cancer Center at the University of Nebraska Medical Center (UNMC) conducting a wide range of basic, clinical, translational and population science cancer research. The Cancer Center Direct | Health and Human Services, Department of / National Institutes of Health | 9/20/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $255,077 | Grant | Trans-NIH Recovery Act Research Support: The Center for Ulcer Research and Education (CURE) was founded nearly 35 years ago by Dr. Morton I. Grossman, a pioneer of gastrointestinal (GI) endocrinology. Its original mission was the study and cure of peptic ulcer disease. Over the years, the Center | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| BAYLOR COLLEGE OF MEDICINE | $892,860 | Grant | Trans-NIH Recovery Act Research Support: 'We propose to enrich the technology infrastructure of our Cryo-EM P41 CenterWe propose to enrich the technology infrastructure of our Cryo-EM P41 Center by 1) automating the cryospecimen preparation with microfluidity and robotics engineering technologie | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| YALE UNIVERSITY | $854,129 | Grant | Trans-NIH Recovery Act Research Support: Our work in both rodents and primates has indicated that the biochemical and behavioral effects of withdrawal from repeated phencyclidine (PCP) form a useful model of the cognitive deficits of schizophrenia. PCP exposure imparts a lasting and regionally-s | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF UTAH, THE | $75,600 | Grant | Trans-NIH Recovery Act Research Support: Project summary: The long-term goal of the proposed research is to understand the molecular mechanisms of synaptic plasticity. Heterotrimeric G proteins have been implicated as regulators of synaptic plasticity in various organisms, but the mechanisms by | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $99,991 | Grant | Trans-NIH Recovery Act Research Support: There are currently over 250,000 survivors of childhood cancer in the U.S. Recent diagnostic therapeutic advances in pediatric oncology have led to greater survival rates in children and young adults with malignancies. However, while cancer therapies impr | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| COLD SPRING HARBOR LABORATORY ASSOCIATION, INC. | $258,373 | Grant | Trans-NIH Recovery Act Research Support: Cell migration and invasion are critical to cancer progressiona nd metastasis, and a better understanding the mechanism and regulation of these processes could suggest new approaches for controlling cancer. Missing in Metastasis (MIM) is an actin-binding | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $2,998,501 | Grant | Trans-NIH Recovery Act Research Support: The OHSU Knight Cancer Institute (Knight) has a history of running high-impact Phase I clinical trials, including imatinib, calcitriol and most recently MDV-3100. As part of the Phase I studies, Knight investigators have developed pharmacodynamic and mol | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF HAWAII SYSTEMS | $1,313,830 | Grant | Trans-NIH Recovery Act Research Support: The Cancer Research Center of Hawaii (CRCH) is an NCI-designated Clinical Cancer Center. CRCH has diverse responsibility in cancer research, education, community outreach, and patient care. It is the only such institution in the State of Hawaii. Hawaii of | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $350,412 | Grant | Trans-NIH Recovery Act Research Support: The success of molecularly targeted cancer therapy using tyrosine kinase inhibitors (TKIs) faces a number of difficult challenges. Foremost among these is the ability to identify subsets of different cancers that are uniquely sensitive to targeted agents, | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $63,914 | Grant | Trans-NIH Recovery Act Research Support: Exposure of a fetus to ethanol can lead to the development of fetal alcohol syndrome, which is characterized by various morphological and behavioral deficits in fetal alcohol-exposed (FAE) offspring. These offspring often show clinical sleep-wake disturba | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| YALE UNIVERSITY | $58,015 | Grant | Trans-NIH Recovery Act Research Support: The proposed supplement will fund a summer research experience for four local science educators from non-research-intensive colleges and universities in the New Haven, CT-area to work on a double-blind, placebo controlled trial to test the efficacy of nal | Health and Human Services, Department of / National Institutes of Health | 7/10/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $315,634 | Grant | Trans-NIH Recovery Act Research Support: Title: An in vitro Model for HIV Latency in Primary Cells We have requested this supplement to provide an opportunity to rapidly accelerate identification of compounds with potential clinical utility in activation/elimination therapeutic strategies to ta | Health and Human Services, Department of / National Institutes of Health | 7/21/2009 |
| UNIVERSITY OF ARKANSAS SYSTEM | $60,000 | Grant | Trans-NIH Recovery Act Research Support: This supplement application is for the purpose of immediately purchasing a Fast Protein Liquid Chromatography (FPLC) system that will greatly increase the throughput and tempo of the research projects outlined in the parent R01 grant (DA026423). In this R | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF KANSAS CENTER FOR RESEARCH, INC. | $50,000 | Grant | Trans-NIH Recovery Act Research Support: PA-07-070 Parent Research Grant | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF MASSACHUSETTS | $43,362 | Grant | Trans-NIH Recovery Act Research Support: Funds were requested to support two undergraduate students summer research. One student employed high-throughput yeast two-hybrid assays to identify transcription factor dimers that may function in the C. elegans digestive tract. The other student employe | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| YALE UNIVERSITY | $457,983 | Grant | Trans-NIH Recovery Act Research Support: Children with asthma may be particularly sensitive to fine particulate matter ( 2.5 m in aerodynamic diameter, PM2.5). The parent grant is investigating the effects of variations in outdoor concentrations of PM2.5 and PM2.5 elemental speciation on asthma | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $20,639 | Grant | Trans-NIH Recovery Act Research Support: This is an ARRA award to R01 EY11379 entitled, 'Functional Organization of Visual Area MT' employed two students for the summer of 2009 and 2010 to participate in a summer research experience. | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| NEW YORK UNIVERSITY (INC) | $181,469 | Grant | Trans-NIH Recovery Act Research Support: The long-term objective of this project is to understand the molecular basis for soma-germline interactions that govern germline proliferation and meiotic entry. In humans, sterility can result from insufficient proliferation of germ cells or from develop | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $97,513 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Post-transcriptional regulation has emerged as a potent way to control quantitatively and qualitatively gene expression. The RNase III family of double-stranded RNA endonucleases plays crucial functions in multiple gen | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE | $252,120 | Grant | Trans-NIH Recovery Act Research Support: Vitamin A is clearly an essential nutrient, but its actions in the body are not clearly understood. Retinoic acid (RA) is a signaling molecule derived from vitamin A that regulates gene expression, thus providing a powerful mechanism through which vitami | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF WYOMING | $131,084 | Grant | Trans-NIH Recovery Act Research Support: The mammalian pRb family members are well-established regulators of cell cycle progression, quiescence and differentiation and have also been reported to play roles in genome stability and cellular senescence. Notably, mutations that lead to the functiona | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE | $191,000 | Grant | Trans-NIH Recovery Act Research Support: This Administrative Supplement is intended to accelerate the pace of discovery of Specific Aim 3 of the parent grant. A major focus of the parent grant was on the function of a protein, PRC1, which is important to cell cleavage. In the Specific Aim (refe | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $131,182 | Grant | Trans-NIH Recovery Act Research Support: The research will make cryo-electron microscopy a technique of choice for atomic-resolution structure determination of large complexes, thus accelerating its potential applications in drug discovery. The requested fund is for hiring a recently graduated A | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $368,172 | Grant | Trans-NIH Recovery Act Research Support: Tracking membrane transport by DEER and TR-WAXS The goal of this project is to understand the molecular mechanism of intestinal glucose and sodium transport. The intestine is responsible for the absorption of dietary carbohydrate and more than 4 liters of | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $81,963 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplemental award for the titled project, Cell-Cell Communication in Xenopus Development was to investigate the novel hypothesis that Wnt inhibits the degradation of proteins following GSK3 phosphorylations and polyubiquitinylation. | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $76,289 | Grant | Trans-NIH Recovery Act Research Support: We have conducted experiments as proposed and observed that it is essential to add experiments related to the Cocaine and Amphetamine Related Transcript (CART) so that we can examine the two key anorexigenic peptides. These two anorexigenic peptides are a | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| SAN DIEGO STATE UNIVERSITY FOUNDATION | $72,860 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplement is to create new jobs for our current project that will help to accelerate the analysis of our data and accelerate the publication and translation into policy of results from our research. Our goal in the overall project is | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF ARKANSAS SYSTEM | $87,000 | Grant | Trans-NIH Recovery Act Research Support: Communication between platelet SERT and plasma 5HT: For the first time, we demonstrate that chronically elevating plasma 5HT in vivo by osmotic minipump in normal C57BL/6J mice results in a loss of surface SERT in platelets and a corresponding increase | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| YALE UNIVERSITY | $186,034 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of our research is to elucidate the cellular and circuit mechanisms of decision making and its executive control. Flexible behavior in humans and animals relies on the brain's ability to accumulate information over time, deliberate abou | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| MEDICAL COLLEGE OF WISCONSIN, INC., THE | $134,894 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplement is to support the research and career development of Emmanuel Ngui, DrPH by deepening his understanding of ethical issues in genetic research, particularly research related to his work examining racial/ethnic disparities in | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| YALE UNIVERSITY | $45,312 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplement is to accelerate the tempo of the parent grant while engaging 6 students, including 3 young adults in high school, college or trade school from the New Haven community that have backgrounds similar to that of our study parti | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| UNIVERSITY OF TENNESSEE | $35,527 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement grant requests Recovery Act Funds to provide up to three individuals (two students and one science educator) with part-time summer jobs over a two year period, as team members of a cutting-edge NINR-funded research study at | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| UNIVERSITY OF TENNESSEE | $130,237 | Grant | Trans-NIH Recovery Act Research Support: The global hypothesis of the parent project is that phasic bursting in vasopressin neurons can be explained largely by the understanding of one potassium current, its modulation by Ca++, and its autoregulation by the dendritically co-released neuropeptide | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $250,088 | Grant | Trans-NIH Recovery Act Research Support: his is an administrative supplement to a funded project focused on accelerating the pace of genetic association studies of Gilles de la Tourette Syndrome (GTS) in population isolates. It is one of three linked applications (together with NS040024 and NS01 | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $860,439 | Grant | Trans-NIH Recovery Act Research Support: This is an administrative supplement for our clinical trial entitled, G?A Combination Trial of Copaxone Plus Estriol in Relapsing-Remitting Multiple Sclerosis.G? The requested funds will accomplish three missions: 1) Achieve ARRA economic goals, 2) Prov | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $128,826 | Grant | Trans-NIH Recovery Act Research Support: THE ROLE OF TRAUMATIC BRAIN INJURY STRESS RESPONSE ON EXERCISE THERAPY 1a Award Description Supplement to our active RO1 grant (5R01NS61960-2, PI: Grace Griesbach) entitled The role of traumatic brain injury stress response on exercise therapy. The paren | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF WYOMING | $273,064 | Grant | Trans-NIH Recovery Act Research Support: This project is designed to facilitate efforts under the parent project to elucidate and manipulate protein N-glycosylation pathways in lepidopteran insect cell systems. These efforts have allowed us to develop important, new, insect-based recombinant gly | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $20,377 | Grant | Trans-NIH Recovery Act Research Support: This is an application requesting administrative supplement to an awarded grant entitled Quantitative Salivary Proteomics for Human Oral Cancer (RO3DEO17144). To facilitate our proposed studies in the parent grant, we plan to recruit two summer student as | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $85,809 | Grant | Trans-NIH Recovery Act Research Support: The project belongs to the area of neurological disorders, and particularly to the field of epilepsy and its therapy. The proposal examines therapeutic antiepileptic potential of four novel pharmacological and dietary interventions in an animal model of e | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| SAN DIEGO STATE UNIVERSTIY FOUNDATION | $319,248 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of the SDSU IMSD Program is to increase the number of SDSU underrepresented minority students who will enter Ph.D. programs in the biomedical sciences. Through year-round research training, mentoring and academic and professional developm | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| YALE UNIVERSITY | $36,857 | Grant | Trans-NIH Recovery Act Research Support: Among the consequences of normal aging, one of the most distressing is decline in memory. The associated loss of productivity, physical health, and sense of well-being will create an increasing number of critical economic and public health issues as the U | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| YALE UNIVERSITY | $258,350 | Grant | Trans-NIH Recovery Act Research Support: This supplement is requested to develop a version of the existing CBT4CBT program that is applicable to alcohol using individuals, using a web-based format. The CBT4CBT program was developed for drug abusers and in a DVD/CD Rom format, largely because at | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| YALE UNIVERSITY | $135,351 | Grant | Trans-NIH Recovery Act Research Support: An administrative supplement is requested for a grant that has two broad research themes: the roles of anion transporter SLC26A6 and related transporters in proximal tubule NaCl transport; and the roles of SLC26A6 and related transporters in mediating int | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| CHILDREN'S HOSPITAL & RESEARCH CENTER | $822,249 | Grant | Trans-NIH Recovery Act Research Support: Many biomarkers are responsive to oxidative stress and modulating effects of antioxidant dietary supplements, but the disease relevance of these markers is uncertain because of the lack of known functional or mechanistic linkages. We propose that mutation | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF TENNESSEE | $449,896 | Grant | Trans-NIH Recovery Act Research Support: The main objective of the parent RC-1 grant G?Development of a Novel Gastrointestinal RadiomitigatorG? (AI 078514, 09/01/07 - 02/28/10) was to determine the therapeutic efficacy of octadecenyl thiophosphate (OTP), a novel radiomitigator using mouse and no | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| CHILDREN'S HOSPITAL & RESEARCH CENTER | $233,101 | Grant | Trans-NIH Recovery Act Research Support: The gastrointestinal syndrome is a deadly and untreateble consequence of radiation injury to the gut from clinical radiotherapy or unplanned exposures such as criticality accidents and terrorism. Novel biomarkers to predict gastrointestinal syndrome and p | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| YALE UNIVERSITY | $98,792 | Grant | Trans-NIH Recovery Act Research Support: The Yale Biomedical Informatics Research Training Program is directed by Prof. Perry L. Miller and is based n the Yale Center for Medical Informatics (YCMI) and many other academic units at Yale, reflecting the diversity of Yale's collaborative Biomedical | Health and Human Services, Department of / National Institutes of Health | 7/23/2009 |
| UNIVERSITY OF KANSAS CENTER FOR RESEARCH, INC. | $36,464 | Grant | Trans-NIH Recovery Act Research Support: This application requests continued support for the doctoral training program in Dynamic Aspects of Chemical Biology in the Departments of Chemistry, Medicinal Chemistry, Molecular Biosciences, and Pharmaceutical Chemistry at the University of Kansas. Thi | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| SAN DIEGO STATE UNIVERSTIY FOUNDATION | $130,368 | Grant | Trans-NIH Recovery Act Research Support: The joint doctoral program (JDP) in Public Health offered by SDSU's Graduate School of Public Health and the UCSD's School of Medicine is an ideal setting for training future investigators who may bridge the two disciplines: behavioral and biological/biom | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| YALE UNIVERSITY | $99,000 | Grant | Trans-NIH Recovery Act Research Support: The overall aim of this proposal is the development of deoxynucleoside analogs for the treatment of cancer. This includes studies on the mechanism of action and resistance of novel nucleoside analogs as well as the exploration of novel strategies to use n | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| YALE UNIVERSITY | $290,304 | Grant | Trans-NIH Recovery Act Research Support: One of the biggest challenges moving discovery to clinical intervention is the timely and cost effective launching and completion of clinical research studies and the development of support models to aid clinical research management. The Clinical and Tran | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| YALE UNIVERSITY | $386,633 | Grant | Trans-NIH Recovery Act Research Support: Prediabetes, the transition phase between normal glucose tolerance and T2DM, is a crucial time for intervention as the progression to T2DM in children is more rapid than in adults. We have shown that 1 out of every 4-5 obese children seen in the Yale Pedi | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $50,000 | Grant | Trans-NIH Recovery Act Research Support: The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins has been participating in the planning activities associated with the project entitled ADOPTion of New Technologies for Remote Data Capture and Protocol Authoring by providing appropriate clin | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH | $478,830 | Grant | Trans-NIH Recovery Act Research Support: This award is issued in response to Notice OD-09-060, Recovery Act Administrative Supplements Providing Summer Research Experiences for Students and Science Educators. DESCRIPTION (provided by applicant): Memorial Sloan-Kettering Cancer Center (MSKCC) Mem | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $364,163 | Grant | Trans-NIH Recovery Act Research Support: The UAB Comprehensive Cancer Center is requesting equipment to support a new caBIG compatible Clinical Trials Management System (CTMS). The equipment requested is manufactured by companies, Dell Inc. and Buffalo Technologies Inc., with U.S. headquarters. | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $172,800 | Grant | Trans-NIH Recovery Act Research Support: AIDS International Training and Research Program - ARRA This award provides funding for a postdoctoral fellow to conduct global health research on the use of HAART for asymptomatic HIV positive women in Lilongwe, Malawi. The study builds on current rese | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| THE VANDERBILT UNIVERSITY | $172,800 | Grant | Trans-NIH Recovery Act Research Support: This post-doctoral training project focuses on a child clinical psychologist currently working at the Judge Baker Children's Center, Harvard Medical School. The child clinical psychologist has expertise in the implementation and dissemination of evidence- | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| SYRACUSE UNIVERSITY | $71,200 | Grant | Trans-NIH Recovery Act Research Support: The long-term objective of the proposed project is to provide the public health (PH) workforce with improved access to high quality, relevant PH grey literature reports in order to positively impact the planning, conducting, and evaluating of PH intervent | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| MOREHOUSE SCHOOL OF MEDICINE, INC., THE | $1,578,280 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this administrative supplement is to establish a developmental program encompassing the general area of Regenerative Medicine and falling under the umbrella of the theme of our current MSMRCMI grant 'Tissue Protection and Reparative Mechani | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| PONCE MEDICAL SCHOOL FOUNDATION INC | $120,750 | Grant | Trans-NIH Recovery Act Research Support: In the present administrative application we are requesting financial support to sponsor summer research experiences for four (4) High School science educators and four (4) High School students. This administrative supplement will be requested through ou | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $54,000 | Grant | Trans-NIH Recovery Act Research Support: This project is a Research Development Support supplement for a Career Development Award (Parent Grant K08 DK078046-02 - Matrilysin regulation in colonic epithelial cells and role in barrier function). The descriptive title of this project is Intestine-sp | Health and Human Services, Department of / National Institutes of Health | 8/24/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $107,100 | Grant | Trans-NIH Recovery Act Research Support: The supplement was intended to accelerate the pace of the parent grant K08MH079088 and as a result to retain the new PI in the workforce. A new position for a trainee was also proposed. We have created a position for a research technician and hired Math | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| BAYLOR COLLEGE OF MEDICINE | $54,000 | Grant | Trans-NIH Recovery Act Research Support: Purpose: to enhance our understanding of human visual processing and perception. Abstract: The ability to identify and discriminate an endless array of visual objects is a challenge to even the most powerful computers, yet humans can rapidly make these d | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| WASHINGTON UNIVERSITY, THE | $99,999 | Grant | Trans-NIH Recovery Act Research Support: Washington University is fortunate to have an outstanding vision research community complementing a largeand busy clinical service. This combination of research and clinical resources make the University anexcellent institution for the training of physici | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| UNIVERSITY OF ARIZONA | $321,129 | Grant | Trans-NIH Recovery Act Research Support: Until the present, PERT trainees have had outstanding success in obtaining tenure-track positions at R1 Universities, and the program itself has had a greater number of such placements than comparison groups at the University of Arizona. However, in the | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $60,500 | Grant | Trans-NIH Recovery Act Research Support: Many human disorders such as cancer come about because genes are not regulated properly. One way genes are controlled is by how they are packaged. New drugs are needed to specifically alter the packaging of cancer genes. We have identified over twenty | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| THE VANDERBILT UNIVERSITY | $49,995 | Grant | Trans-NIH Recovery Act Research Support: The aim of this administrative request is to preserve a unique research resource, enhancing the follow-up participation of the clinical study, the Tennessee ChildrenG??s Respiratory Initiative, and increasing the capacity for data analysis. The Tennessee | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $107,775 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement builds on the applicant's current K-24 award. Specifically, the third component of the program project outlined in the original K-24 award focused on utilizing clinical/radiologic findings from patients presenting with inde | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF HAWAII SYSTEMS | $49,950 | Grant | Trans-NIH Recovery Act Research Support: This revised proposal is resubmitted to request support for B. Christopher Frueh, Ph.D. in his continued efforts to mentor clinical investigators and to conduct patient-oriented mental health services research. His main interest is mental health service d | Health and Human Services, Department of / National Institutes of Health | 7/31/2009 |
| UNIVERSITY OF ARIZONA | $108,000 | Grant | Trans-NIH Recovery Act Research Support: This supplement is requested to accelerate the pace of research described in the parent application K25CA120350. The overall goal of that project is the development of a novel class of near infrared agents for applications in diagnostic imaging and therap | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC. | $54,000 | Grant | Trans-NIH Recovery Act Research Support: The objective of our research is to investigate the functional contributions of chemokine signaling interactions with TGF-beta signaling in the breast cancer microenvironment using biochemical, molecular biology, cell biology approaches and whole animal m | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF PITTSBURGH THE | $26,894 | Grant | Trans-NIH Recovery Act Research Support: Cancer and congenital malformations occasionally may have a common etiology. We have recently demonstrated that cleft families present a higher incidence of family history of cancer and that AXIN2, a gene that when mutated increases susceptibility to colo | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| THE JACKSON LABORATORY | $54,000 | Grant | Trans-NIH Recovery Act Research Support: Autoimmune Type 1 Diabetes (T1D) results from autoimmune destruction of insulin-producing pancreatic beta cells. The overall goal of this proposal is to further determine how the defects in immunological tolerance induction underlying T1D in the NOD mous | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF PITTSBURGH THE | $89,758 | Grant | Trans-NIH Recovery Act Research Support: In the parent grant, we hypothesized that pro-oxidant pesticides inducing similar clinical manifestations - rotenone and paraquat - will have different initial sites of action. Therefore, in the precocious phases of intoxication, they will cause oxidation | Health and Human Services, Department of / National Institutes of Health | 8/12/2009 |
| TUFTS MEDICAL CENTER PARENT, INC. | $128,250 | Grant | Trans-NIH Recovery Act Research Support: Polycythemia vera (PV) is a human disease where too many red blood cells are produced. Current treatment for PV is inadequate due to blood clotting problems abd development of leukemia. In this proposal, a mouse model of PV will be used to better unders | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| DANA-FARBER CANCER INSTITUTE, INC. | $1,974,218 | Grant | Trans-NIH Recovery Act Research Support: Most HIV transmissions occur mucosally, including mother-to-child transmission (MTCT). As HIV clade C predominates worldwide, we initially focused on immunoprevention of HIV clade C MTCT. We identified a quadruple (4x) combination of human neutralizing mo | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $97,500 | Grant | Trans-NIH Recovery Act Research Support: This is an administrative supplement request to support research in our Program Project grant P01-CA16519, Molecular and Cellular Basis of Tumorigenesis. This administrative supplement request represents an opportunity to increase the tempo of our researc | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY | $276,166 | Grant | Trans-NIH Recovery Act Research Support: The funds requested were for (a) additional supplies to expand high throughput sequencing of RNA populations, (b) to purchase an essential instrument for quantization of images and (c) to support the extension of a postdoctoral appointment for a year to i | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $6,251,349 | Grant | Trans-NIH Recovery Act Research Support: Large prospective studies of diet and cancer have often not supported hypotheses that were based on animal and ecological findings; one possible explanation could be large measurement errors in the assessment of diet. Thus, the National Cancer Institute ( | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| DANA-FARBER CANCER INSTITUTE, INC. | $514,934 | Grant | Trans-NIH Recovery Act Research Support: Multiple myeloma (MM) affected 14,400 new individuals in the United States in 2001, with 50,000 total patients, and remains incurable despite conventional and high dose therapies. Novel therapeutic interventions are therefore urgently needed with targets | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $1,589,249 | Grant | Trans-NIH Recovery Act Research Support: This is supplemental funding request for a multidisciplinary combined modality program project grant with two major clinical protocols, both dealing with the use of photodynamic therapy (PDT), one for intraperitoneal carcinomatosis and the other for carci | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| BAYLOR COLLEGE OF MEDICINE | $59,392 | Grant | Trans-NIH Recovery Act Research Support: This grant provided a summer research experience for 4 high school students in health-related scientific research. The goal of this program is to expose trainees at the earliest stage of their career to translational research in cell and gene therapy. Thi | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $409,868 | Grant | Trans-NIH Recovery Act Research Support: The incidence of thyroid cancer is rising at the second fastest rate of all malignancies in the United States and has an increasing tumor-specific mortality annually, making it an important public health problem. The reasons for this increasing incidence | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| UNIVERSITY OF ILLINOIS | $225,568 | Grant | Trans-NIH Recovery Act Research Support: Project 1 G?? This project examines the role of Na+/H+ exchangers (NHE) in diarrhea associated with infection by enteropathogenic E. coli (EPEC). EPEC inhibition of NHE3 may contribute to the pathophysiology of associated diarrhea. EPEC, however, stimula | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $198,256 | Grant | Trans-NIH Recovery Act Research Support: Nephrolithiasis is a common, costly and recurrent condition, but there is sparse information on the influence of genetic factors and gene-environment interactions. The overall long-term objective of this Program Project is to expand our knowledge of the p | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| BAYLOR COLLEGE OF MEDICINE | $1,261,211 | Grant | Trans-NIH Recovery Act Research Support: This program is comprised of four highly interactive projects from Baylor College of Medicine (BCM) and M.D. Anderson Cancer Center (MDACC) in the Texas Medical Center (TMC) in Houston that focus on different aspects of the regulation of self-renewal and | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF OREGON | $47,540 | Grant | Trans-NIH Recovery Act Research Support: We received an administrative supplement with ARRA funding to support a summer outreach research and training program. The supplement provided for opportunities for high school students, undergraduate students, and a high school teacher to immerse themse | Health and Human Services, Department of / National Institutes of Health | 6/02/2009 |
| GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | $192,329 | Grant | Trans-NIH Recovery Act Research Support: The project shall provide unique and fundamental data about the emergence of cognitive competence, for instance by yielding a comparison between multiple primate species on tasks for which a single species has already been tested. The project will allow t | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $256,000 | Grant | Trans-NIH Recovery Act Research Support: The parent grant has three individual projects and a core, and the overall goal of the Program is to determine basic mechanisms of epileptogenesis and seizure generation in order to improve the health of patients with epilepsy. A major direction in the P | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| HENRY FORD HEALTH SYSTEM | $131,850 | Grant | Trans-NIH Recovery Act Research Support: Our preliminary data demonstrate that treatment of aged ischemic rats with sildenafil substantially enhances neurogenesis and improves functional outcomes, although neurogenesis in the SVZ is impaired in aged ischemic animals. These data indicate that eve | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| BAYLOR COLLEGE OF MEDICINE | $120,000 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the funding is to increase enrollment in a clinical trial of erythropoietin in TBI patients (Projects 1 and 2), and to purchase equipment for Project 3. Projects 1 and 2 of our grant are a clinical trial of 200 severe TI patients. The goa | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $88,917 | Grant | Trans-NIH Recovery Act Research Support: Alexander disease is a rare and typically fatal neurodegenerative disease that results from heterozygous mutations in the gene encoding the type III intermediate filament protein GFAP. The pathological signature of the disorder is the Rosenthal fiber, a c | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $153,563 | Grant | Trans-NIH Recovery Act Research Support: The new personnel continue to be involved in Project 2 by performing TBI in swine, performing MRI and biomarker data collection and performing extensive histopathological analyses. They will interface with the other projects and cores of the Program for a | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF LOUISVILLE | $100,905 | Grant | Trans-NIH Recovery Act Research Support: This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in oth | Health and Human Services, Department of / National Institutes of Health | 8/23/2009 |
| UNIVERSITY OF NEBRASKA | $199,000 | Grant | Trans-NIH Recovery Act Research Support: The Nebraska Center for Virology (NCV) is making tremendous strides toward achieving its goal of becoming a Center of Biomedical Research Excellence in Virology. One way it is doing this is through support of five thematically-linked research projects dir | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE | $820,132 | Grant | Trans-NIH Recovery Act Research Support: The goals of the COBRE Neuroscience Supplement 3P20 RR016435-09S2 are specifically directed to further strengthen the neuroscience research infrastructure at the University of Vermont by three mechanisms: (a) supporting technical positions in laboratorie | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| MOUNT DESERT ISLAND BIOLOGICAL LABORATORY (INC) | $617,932 | Grant | Trans-NIH Recovery Act Research Support: The Maine IDeA Network of Biomedical Research Excellence (ME-INBRE) in Comparative Functional Genomics is led by the Mount Desert Island Biological Laboratory and is composed of two research institutions, one graduate degree granting institution, seven un | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC. | $575,701 | Grant | Trans-NIH Recovery Act Research Support: The Kansas IDeA Network of Biomedical Research Excellence (K-INBRE, first known as the K-BRIN) was established in 2001 as a network of 9 Kansas institutions of higher learning. Kansas falls into the bottom half of states receiving research funding from th | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $651,170 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplement is to establish new infrastructure in the Center for Oral Health Research (COHR) to address translational oral cancers needs at MUSC; and provide additional staff in the COHR to initiate oral cancer support-related activitie | Health and Human Services, Department of / National Institutes of Health | 8/25/2009 |
| SOUTH CAROLINA RESEARCH FOUNDATION | $400,000 | Grant | Trans-NIH Recovery Act Research Support: CENTER FOR COLON CANCER RESEARCH The long-term goal of this study is to leverage our combined experience in nanotechnology, cancer biology and stem cell biology to develop novel strategies for understanding cancer stem cells (CSCs). CSCs are thought to be | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| NEMOURS FOUNDATION, THE | $197,625 | Grant | Trans-NIH Recovery Act Research Support: The primary goal of this COBRE proposal is to increase the number of active, NIH-funded biomedical researchers in the State of Delaware. This will be accomplished through the efforts of a multidisciplinary group of investigators at the Nemours Research In | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE | $393,646 | Grant | Trans-NIH Recovery Act Research Support: ARRA funds will be used to launch two pilot projects that involve nearly all COBRE faculty to foster collaborations. We specifically plan to obtain critical new information regarding the interaction of microorganisms that we study with two early innate h | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| LOUISIANA STATE UNIVERSITY SYSTEM | $344,630 | Grant | Trans-NIH Recovery Act Research Support: T cell based therapies for cancer in the form of adoptive T cell transfer (ACT) or cancer vaccines can kill tumors expressing immunodominant tumor antigens. However, this process allows the escape of tumor cells expressing poorly immunogenic or subdomina | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE | $196,728 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this supplement proposal is to advance the aims and goals of the present Center of Biomedical Research Excellence (COBRE) P20 RR15557 (PI: Irvin) program is to create a sustainable center of research excellence in Lung Biology and Dise | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| NATIONAL BUREAU OF ECONOMIC RESEARCH, INC. | $193,920 | Grant | Trans-NIH Recovery Act Research Support: Advancing the Application of Medicare Claims Records for Health Care Research The goal of this supplement is to accelerate the development of researcher-friendly database resources that are constructed from Medicare claims records. The first projec | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $75,334 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): This is an application to continue the Michigan Center for Urban African American Aging Research (MCUAAAR) at the University of Michigan and Wayne State University. Conceptually, the research and training activities of | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| HEALTH RESEARCH, INC. | $173,231 | Grant | Trans-NIH Recovery Act Research Support: RPCI is committed to focusing clinical research resources on processes that will improve the efficiency and effectiveness of study implementation, participant accrual and study data collection with an emphasis on investigator-initiated studies and Phase I | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $1,472,500 | Grant | Trans-NIH Recovery Act Research Support: The Ohio State University Comprehensive Cancer Center (OSUCCC) is currently in its 29th year as an NCI-designated CCC and is now requesting continued federal support for the next five years. The OSUCCC named its 4th Director, Michael A. Caligiuri, M.D. in | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $49,999 | Grant | Trans-NIH Recovery Act Research Support: Our Cancer Center agrees to participate in the planning activities associated with the project entitled ADOPTion of New Technologies for Remote Data Capture and Protocol Authoring (ADOPT) by providing appropriate clinical and informatics expertise in s | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $362,400 | Grant | Trans-NIH Recovery Act Research Support: The University of Minnesota Cancer Center (UMCC) is a NCI-designated Comprehensive Cancer Center dedicated to cancer research, education, and patient care for the citizens of the state of Minnesota and surrounding region. Since the time of the first award | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| WASHINGTON UNIVERSITY, THE | $250,497 | Grant | Trans-NIH Recovery Act Research Support: The Alvin J. Siteman Cancer Center (SCC) at Washington University School of Medicine and Barnes-Jewish Hospital received NCI designation as a Clinical Cancer Center in 2001, and as a Comprehensive Cancer Center in 2004. The SCC is composed of eight multid | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF MARYLAND | $1,500,000 | Grant | Trans-NIH Recovery Act Research Support: The mission of the University of Maryland Marlene and Stewart Greenebaum Cancer Center is to undertake innovative basic and clinical research which will impact the understanding and treatment of cancer around the world and to provide state-of-the-art clin | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| EMORY UNIVERSITY | $50,000 | Grant | Trans-NIH Recovery Act Research Support: ADOPTion of New Technologies for Remote Data Capture and Protocol Authoring (ADOPT) The NCI has made significant progress in reconfiguring the NCI trials infrastructure to allow investigators to take full advantage of scientific opportunities. In order fo | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | $1,123,929 | Grant | Trans-NIH Recovery Act Research Support: This Administrative Supplement Award will be used to recruit a newly-independent, tenure track physician- scientist at the Assistant Professor level to the Moffitt Cancer Center (MCC). As required by the supplement, this person will be a laboratory-based | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| ST LUKE'S-ROOSEVELT HOSPITAL CENTER | $300,000 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplement grant is to provide funds for equipment purchases for the Core Laboratories of the NY Obesity Nutrition Research Center and to increase the funding for the Pilot and Feasibility Program. The P/F Program is now awaiting appl | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF WASHINGTON | $298,564 | Grant | Trans-NIH Recovery Act Research Support: The major goal of the Clinical Nutrition Research Unit (CNRU) at the University of Washington is to promote and enhance interdisciplinary nutrition research by bringing together basic science and clinical investigators on a cooperative basis. This request | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| BOSTON MEDICAL CENTER CORPORATION | $187,105 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement supports the Center's ongoing programs and Core as follows: A) Pilot and Feasibility Program (Administrative Core: Lee M. Kpaln, MD, PhD, Associate Director): These supplemental funds enable the Center to accomplish the foll | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $295,456 | Grant | Trans-NIH Recovery Act Research Support: This application is for a 5 year renewal of the Colorado Clinical Nutrition Research Unit (CNRU). The Colorado CNRU was originally funded in January, 1995 to serve 41 investigators. Now, in our eleventh year of operation, we serve 67 investigators.The bro | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $238,608 | Grant | Trans-NIH Recovery Act Research Support: The University of Southern California Research Center for Liver Diseases, funded since 1995, has the goal of fostering and facilitating interdisciplinary research in liver and digestive disease. The Center has 41 members and 17 affiliated members. The Bio | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $299,999 | Grant | Trans-NIH Recovery Act Research Support: The mission ofthe Minnesota Obesity Center is to find ways to prevent weight gain, and the onset of obesity and complications of obesity. Obesity is a major source of illness and death, and is the most common nutritional ailment in the United States. Litt | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| UNIVERSITY OF IOWA, THE | $300,000 | Grant | Trans-NIH Recovery Act Research Support: The development of effective gene therapies for inherited disorders requires interdisciplinary programs that focus on the identification of disease genes, an elucidation of disease pathogenesis, and the development of technologies for genetic modulation. | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| THE WASHINGTON UNIVERSITY | $300,000 | Grant | Trans-NIH Recovery Act Research Support: This application seeks continued funding for the Washington University CNRU. Since our CNRU was originally funded in 1999, it has served as a nidus for the growth and development of nutrition research at Washington University. The research infrastructure | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $148,000 | Grant | Trans-NIH Recovery Act Research Support: Title: Generation of Novel AAV Variants by Directed Evolution for Improved CFTR Delivery to Airway Epithelium In Vitro and In Vivo. This project is to generate novel adeno-associated virus (AAV) vectors through an in intro evolution technique by using mod | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF PITTSBURGH THE | $113,625 | Grant | Trans-NIH Recovery Act Research Support: The airway inflammatory milieu of patients with cystic fibrosis (CF) is replete with reactive oxygen species (ROS), nitric oxide (NO), and secondary oxides of nitrogen (NOx). Consequently, a multitude of oxidized and nitrated products are formed in protei | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| BAYLOR COLLEGE OF MEDICINE | $675,500 | Grant | Trans-NIH Recovery Act Research Support: 'The overall goal of the DERC is to promote diabetes research in clinical metabolism and nutrition. Scope of the Overall Project: This Diabetes Endocrinology Research Center (DERC) application was submitted under a P30 grant mechanism in response to a RF | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| CHILDREN'S HOSPITAL CORPORATION, THE | $172,482 | Grant | Trans-NIH Recovery Act Research Support: This Center grant requests funding for seven Core facilities to support a broadly-based research program in the study of mental retardation and developmental disabilities. The seven Core facilities are: Administrative, Proteomics, Cellular Neuroscience, I | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $125,634 | Grant | Trans-NIH Recovery Act Research Support: This grant provided a summer research experience for 9 high school students and one science educator in health-related scientific research. All participants were affiliated with Gregorio Luperon High School, a Mathematics and Science High School for Latin | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| BRANDEIS UNIVERSITY | $355,784 | Grant | Trans-NIH Recovery Act Research Support: This is to continue NINDS funding of a Core Facility at Brandeis University. This will allow us to fully exploit the three subcomponents that are now firmly established: a microarray and FACS facility, an imaging facility and a mouse/transgenic facility. | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF MIAMI | $82,129 | Grant | Trans-NIH Recovery Act Research Support: The California sea hare, Aplysia californica, is a large marine snail with a very simple nervous system. The National Resource for Aplysia, located at the Rosenstiel School of Marine and Atmospheric Science of the University of Miami, raises and ships 25, | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| SOUTH CAROLINA RESEARCH FOUNDATION | $343,792 | Grant | Trans-NIH Recovery Act Research Support: PEROMYSCUS LABORATORY MODELS FOR BIOMEDICAL RESEARCH The Peromyscus Genetic Stock Center (PGSC) provides disease-free peromyscines to researchers worldwide, and promotes the use of Peromyscus through development of genomic, reproductive,preservation and g | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| WAKE FOREST UNIVERSITY | $305,356 | Grant | Trans-NIH Recovery Act Research Support: This application proposes the acquisition of resources (personnel and equipment) that will enhance and accelerate the translational activities conducted in two NCRR-supported Animal and Biological Materials Resources (ABMR): 1) the Vervet Research Colony | Health and Human Services, Department of / National Institutes of Health | 8/20/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $977,344 | Grant | Trans-NIH Recovery Act Research Support: These supplemental funds will create a yeast modENCODE-like database to enhance the SGD budding yeast resource, enhance the analysis of modENCODE data, facilitate the advancement of science with the incorporation of yeast systematic results into a wide va | Health and Human Services, Department of / National Institutes of Health | 9/10/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $236,486 | Grant | Trans-NIH Recovery Act Research Support: The primary goals of the proposed supplementary effort are two-fold and concern accelerating the pace of research within the scope of the parent award LM-7085 (P41). First, we will accelerate the pace of work to directly address the issues that limit prog | Health and Human Services, Department of / National Institutes of Health | 7/23/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $517,481 | Grant | Trans-NIH Recovery Act Research Support: Title: Development of Medical Biophotonic Technologies for Imaging and Therapy. This administrative supplement to the Laser Microbeam and Medical Program (LAMMP P41RR01192) supports LAMMP core 3, Virtual Photonic Technologies (VPT). Specifically, we seek | Health and Human Services, Department of / National Institutes of Health | 8/12/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $1,013,617 | Grant | Trans-NIH Recovery Act Research Support: Title: Development of Bedside Medical Biophotonic Diagnostic Devices. This administrative supplement to the Laser Microbeam and Medical Program (LAMMP P41RR01192) supports LAMMP core 2, Medical Translational Technologies (MTT). Specifically, we seek to s | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF UTAH, THE | $642,303 | Grant | Trans-NIH Recovery Act Research Support: We propose to establish the Center for Integrative Biomedical Computing and, through its work, to address important biomedical research problems in bioelectric fields, imaged-based anatomy, multi-scale tissue modeling and simulation, and scientific visual | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $1,805,902 | Grant | Trans-NIH Recovery Act Research Support: The Neuroimage Analysis Center (NAC), a national resource center, is developing algorithms and image analysis software tools for improving our understanding of brain diseases and enabling innovative treatments. The focus of this competitive renewal is the | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $500,000 | Grant | Trans-NIH Recovery Act Research Support: In this application we seek renewed support for our continued efforts to develop innovative neuroimaging technologies within the highly integrated multimodal framework of our P41 Regional Resource, the Center for Functional Neuroimaging Technologies (CFNT | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $222,389 | Grant | Trans-NIH Recovery Act Research Support: Biomarkers of Exposure to Hazardous Substances Administrative Supplement to Project 3 and collaborating with investigators at the Superfund program at UC San Diego. This project will develop sensitive tools to monitor the contamination of widely used and | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $221,690 | Grant | Trans-NIH Recovery Act Research Support: ?Combining Genomic Data From Model Organisms to Provide Insight into Mode of Action?This award is a collaborative project between two laboratories. Each group is fundamentally focused on understanding the molecular mode of action of toxic chemicals which | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| UNIVERSITY OF TEXAS AT AUSTIN | $145,827 | Grant | Trans-NIH Recovery Act Research Support: Excellent longitudinal data are available on the development of alcohol use and abuse across the college years but little is known about the behavioral risks (e.g. risky sex, aggression, academic failure) that have been associated with collegiate drinking | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE OF | $12,951 | Grant | Trans-NIH Recovery Act Research Support: In utero exposure of humans to high levels of ethanol can result in a variety of neurological anomalies collectively termed alcohol related neurodevelopmental disorders (ARND). Some of the hallmarks of observed cases of ARND bear a striking similarity to | Health and Human Services, Department of / National Institutes of Health | 6/19/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $221,994 | Grant | Trans-NIH Recovery Act Research Support: ARRA -SBRP: Environmental Exposure and Effect of Hazardous Chemicals(Administ Project 6 collaboration with Univ of Arizona - Casey Miller PI This project is a collaboration between Professors Gray and Miller at UNC and Professor Brusseau at the Universit | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $114,967 | Grant | Trans-NIH Recovery Act Research Support: This supplemental funding will provide support for a collaboration between Boston University's Superfund Basic Research Program Research Translation Core and Brown University. The Boston University Superfund Research Program is an interdisciplinary progra | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| DUKE UNIVERSITY | $193,936 | Grant | Trans-NIH Recovery Act Research Support: Collaboration between Duke SBRC Project 6, Developmental Effects of Superfund Hydrocarbon Mixtures in Fundulus heteroclitus (Richard Di Giulio, PI) and University of North Carolina, Chapel Hill SBRC Project 1, The Role of Oxidative Stress in Toxicity and | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| BROWN UNIVERSITY IN PROVIDENCE IN STATE OF RI AND PROVIDENCE PLANTATIONS | $235,632 | Grant | Trans-NIH Recovery Act Research Support: This Superfund Basic Research and Training Program-Reuse in RI: A State-Based Approach to Complex Exposures-tackles through research and outreach three inter-related thematic challenges: 1) land reuse, 2) a state-based approach, and 3) complex exposures. | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $205,253 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of the Alzheimer's Disease Research Center (ADRC) at Johns Hopkins University (JHU) is to facilitate research in Alzheimer's disease (AD) and related disorders throughout the research community at JHU and associated institutions | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF ROCHESTER | $375,000 | Grant | Trans-NIH Recovery Act Research Support: The project comprises 3 enhancements to an existing Center of Research Translation grant, entitled Translating molecular signal pathways to orthopaedic trauma care. The first provides salary support for personnel and animal/supply support to conduct expe | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| DUKE UNIVERSITY | $25,969 | Grant | Trans-NIH Recovery Act Research Support: Glioblastoma Multiforme (GBM) is the most aggressive form of glial neoplasia and accounts for approximately 60% of all malignant primary brain tumors. Although current standard therapy targeting GBM incorporates surgery, radiation, and chemotherapy, patie | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| UNIVERSITY OF MIAMI | $56,304 | Grant | Trans-NIH Recovery Act Research Support: The central focus of the parent grant is to address the health concerns of women and their developing offspring affected by drug abuse by providing the optimal environment to encourage and facilitate clinical and translational research. The approach is to | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $313,873 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): This center program seeks to evaluate the performance of genomic sequence information for predicting health and disease above and beyond traditional risk factors. To accomplish this objective we will develop statistica | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| FLORIDA STATE UNIVERSITY, THE | $229,263 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the administrative supplement is to accelerate the tempo and amount of data acquisition, coding, and analysis for three of the five center projects. This will be accomplished by hiring additional staff, enabling increased hours for current | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF PITTSBURGH THE | $271,288 | Grant | Trans-NIH Recovery Act Research Support: Through the hiring of two new research associates, the requested support will enable us to enhance research goals and capacities through infrastructure support for mulitple investigators by increasing the number of human brains available for study, accel | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF MIAMI | $89,289 | Grant | Trans-NIH Recovery Act Research Support: The goal of Project I is to examine candidate genes based on the convergence of evidence as a PD risk factor from different studies (association, linkage and expression), and to enhance these efforts by including analysis of complex genetic and environmen | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $199,316 | Grant | Trans-NIH Recovery Act Research Support: The goal of this ARRA application is to accelerate the pace of the current scope of the PENN Udall Center while adding retaining jobs. Briefly, the goals of this Udall Center are to elucidate mechanisms of brain degeneration in patients with Parkinson s d | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE | $977,475 | Grant | Trans-NIH Recovery Act Research Support: This NCRR ARRA supplemental application for the Tulane National Primate Research Center (TNPRC) provides two years of funding to support and accelerate translational research efforts at the TNPRC by enhancing information and communication networks for non | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $1,499,216 | Grant | Trans-NIH Recovery Act Research Support: This Administrative Supplement to the New England Primate Research Center (NEPRC) Base Grant (P51 RR000168-48) is to support the development of a new translational laboratory animal model directed at understanding the relationship between common metabolic | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF CHICAGO, THE | $574,400 | Grant | Trans-NIH Recovery Act Research Support: This proposal seeks the continuation of the University of Chicago Diabetes Research and Training Center (DRTC). The Center is an interdepartmental and interinstitutional cooperative endeavor involving investigators from the University of Chicago, Illinois | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| BAYLOR COLLEGE OF MEDICINE | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The primary aim of the parent grant is to identify and characterize bladder cancer stem cells (CSCs), In this administrative supplement, we propose the procurement of a cutting edge technology (the Fluidigm System) that was developed in Stanford Universi | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| MINNEAPOLIS MEDICAL RESEARCH FOUNDATION | $67,524 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the award is to purchase a gas chromatograph (GC) to replace an aging model which is beyond warranty and for which we can no longer get parts or a service contract from the manufacturer. | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF LOUISVILLE | $130,836 | Grant | Trans-NIH Recovery Act Research Support: Recent pilot studies have suggested that plasminogen activator inhibitor-1 (PAI-1) plays a key role hepatic regeneration. This surprising finding is contrary to the dogma that PAI-1 plays an antiproliferative role in hepatic regeneration by inhibiting the | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $230,797 | Grant | Trans-NIH Recovery Act Research Support: The aim of this administrative supplement is to enhance our ability to address the original aims of this grant. We found that a brief exposure to 10-50 mM ethanol prior to cardiac ischemia reduces infarct size by -70% in a process that is dependent on act | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| IDAHO STATE UNIVERSITY | $81,387 | Grant | Trans-NIH Recovery Act Research Support: Under the parent grant, 180 postmenopausal women, 50-65 years of age, were recruited from the general community to participate in a research project on the relationships between moderate/at-risk drinking, cognitive functioning, and the mediating effects o | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC. | $80,520 | Grant | Trans-NIH Recovery Act Research Support: It is well-established that responses to some drugs differ among ethnic groups due to variations in genetic background. Alcohol is one of these agents, with rates of alcoholism being more prominent in certain races than in others. Among the more susceptib | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| UNIVERSITY OF SOUTH FLORIDA | $192,315 | Grant | Trans-NIH Recovery Act Research Support: Adolescents suffer many acute adverse consequences from alcohol use. Recent epidemiological findings have linked adolescence to the development of alcohol abuse and dependence. This co-occurrence suggests that the processes of adolescent development may e | Health and Human Services, Department of / National Institutes of Health | 8/12/2009 |
| NEUROBEHAVIORAL RESEARCH, INC. | $910,861 | Grant | Trans-NIH Recovery Act Research Support: In this proposed competitive revision, we are adding a longitudinal component for people in early abstinence to our funded R01 studying clinical issues and CNS disinhibition in short- and long-term abstinent alcoholics compared to non-alcoholic controls. | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF NEW MEXICO | $125,637 | Grant | Trans-NIH Recovery Act Research Support: According to the U.S. Center for Disease Control, young people under the age of 25 are the segment of the population in the U.S. at the highest risk for HIV and other STDs. Of those under 25, individuals involved in the juvenile justice system are among t | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| MAYO CLINIC | $133,420 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this administrative supplement is to accelerate progress of the parent R01 by defining the secretory phenotype of senescent preadipocytes using expression profiling approaches. This is based on new data since the parent grant was submitted | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| UNIVERSITY OF MARYLAND | $276,723 | Grant | Trans-NIH Recovery Act Research Support: We are submitting a One Year Competing Revision of R01 AG 16613 according to Notice Number NOT-OD-09-058, Notice Title: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. This competing revision supports a signific | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| WAKE FOREST UNIVERSITY | $7,400 | Grant | Trans-NIH Recovery Act Research Support: The most important risk factor for the development of osteoarthritis (OA) is age but the mechanisms by which aging contributes to OA susceptibility are poorly understood. A key feature of OA is the progressive destruction and loss of articular cartilage r | Health and Human Services, Department of / National Institutes of Health | 8/05/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $49,594 | Grant | Trans-NIH Recovery Act Research Support: Our long term goal is to determine the molecular mechanisms underlying the diminished skeletal muscle performance with age. We hypothesize that age-dependent damage of specific amino acid residues in key skeletal muscle proteins impacts skeletal muscle pe | Health and Human Services, Department of / National Institutes of Health | 8/05/2009 |
| SOUTHERN ILLINOIS UNIVERSITY | $60,952 | Grant | Trans-NIH Recovery Act Research Support: Project Title: Interaction of caloric restriction with longevity genes Calorie restriction (CR) and longevity genes related to growth hormone signaling prevent age-related disease, extend healthspan and increase life expectancy. Studies of mice in our la | Health and Human Services, Department of / National Institutes of Health | 9/02/2009 |
| UNIVERSITY OF CHICAGO, THE | $153,583 | Grant | Trans-NIH Recovery Act Research Support: Cerebral deposition of ?-amyloid peptides (A?) is one of the pathological hallmarks of AlzheimerG??s disease. A? is generated by sequential proteolysis of amyloid precursor protein (APP) by BACE1 and ?-secretase. ?-secretase is a multimeric protein comple | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $147,689 | Grant | Trans-NIH Recovery Act Research Support: Manual dexterity is fundamental for maintaining independence in many basic and instrumental activities of daily living. Two important components of skill learning are the learning process itself (motor acquisition), and the ability to transfer what has be | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $421,070 | Grant | Trans-NIH Recovery Act Research Support: Human skin, like all other organs, undergoes alterations as a consequence of the passage of time. In aged human skin, the dermal connective tissue architecture undergoes progressive degradation, which impairs skin function and causes skin to become thin a | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $130,836 | Grant | Trans-NIH Recovery Act Research Support: To accelerate research described in Specific Aim 2 of the parent grant, I am requesting an administrative supplement to hire and support a new Postdoctoral Fellow (Ryan Ragland, Ph.D.) for two years. Our unexpected finding that p53 absence does not rescue | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE | $85,767 | Grant | Trans-NIH Recovery Act Research Support: Aging is not a uniform process among individuals. There are persons who rapidly develop age-related kidney disease, cardiovascular disease, frailty and anemia. The underlying cause(s) of age-related kidney disease are not clear, but glomerulosclerosis is | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| SALK INSTITUTE FOR BIOLOGICAL STUDIES | $97,715 | Grant | Trans-NIH Recovery Act Research Support: Stem cells provide for the maintenance and regeneration of organs and tissues throughout life, and loss of the regenerative capacity of tissues such as blood and muscle has been attributed to decreased stem cell activity. The ability of stem cells to cont | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $164,690 | Grant | Trans-NIH Recovery Act Research Support: Dietary restriction (DR) increases lifespan and delays the onset of age-dependent diseases. The overarching goal of this proposal is to identify the molecular mechanisms underlying the benefits of DR on longevity. The energy-sensing AMP-activated protein | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| THE WASHINGTON UNIVERSITY | $45,000 | Grant | Trans-NIH Recovery Act Research Support: Inclusion body myopathies (IBM) are disabling skeletal muscle disorders and considered a prototypical age related muscle disease. There is no effective treatment. IBM muscle has characteristic 'rimmed vacuoles' and eosinophilic inclusions. These structure | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $99,906 | Grant | Trans-NIH Recovery Act Research Support: Aging of the cardiovascular system is characterized by a reduction in cardiac function, and cardiovascular disease frequently strikes in the latter half of life. Many experimental findings suggest that adult mammalian myocardium has a population of reside | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| OKLAHOMA MEDICAL RESEARCH FOUNDATION | $326,000 | Grant | Trans-NIH Recovery Act Research Support: This proposal is in response to Notice Number NOT-OD-09-058, entitled Enabling RPGs to Leverage NCRR Center and Center-like Programs. Specifically, it is a request to add a third Specific Aim, To study lineage stability and directionality of hematopoiesis | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | $34,452 | Grant | Trans-NIH Recovery Act Research Support: This proposal describes the research and training opportunities for two undergraduate students working for 12 weeks in the summers of 2009 and 2010 on RNA editing in African trypanosomes. The parent grant AI021401-24 addresses the mechanism and function o | Health and Human Services, Department of / National Institutes of Health | 8/20/2009 |
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $100,000 | Grant | Trans-NIH Recovery Act Research Support: HIV-1 reverse transcriptase (RT) is a central target for antiviral treatment of AIDS and detailed knowledge of its structure and function has important clinical and biological consequences. Both nucleoside and non-nucleoside RT inhibitors are used as effe | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| NEW YORK MEDICAL COLLEGE | $173,789 | Grant | Trans-NIH Recovery Act Research Support: Funding is for a supplement to a grant entitled, G?Determinants of Borrelia burgdorferi Hematogenous DisseminationG?; the long-term objective of the project was elucidation of genes/proteins that mediate B. burgdorferi virulence. Lyme disease, the most co | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $154,116 | Grant | Trans-NIH Recovery Act Research Support: Enhancing immune effector mechanisms and dampening immune regulation may be controlled by a new cellular circuitry involving Treg and mast cells. The funded grant, 5R01AI048667-07, Effector Mechanisms in Graft Tolerance, demonstrated that mast cells are e | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON | $128,805 | Grant | Trans-NIH Recovery Act Research Support: Tuberculosis has been declared a global emergency by the WHO and a priority for vaccine development by the NIH. The currently used BCG vaccine offers variable protection against children but not adults. Various sub unit and DNA vaccines and attenuated myc | Health and Human Services, Department of / National Institutes of Health | 9/27/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $289,683 | Grant | Trans-NIH Recovery Act Research Support: Mast cells (MCs) are important in allergic diseases, tissue injury, and protection from infections. MC numbers and their effector functions are dynamically regulated by constituents of the tissue microenvironment. This application for continued support fo | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $300,775 | Grant | Trans-NIH Recovery Act Research Support: This project will determine the HIV-l envelope changes necessary for the virus to use different cell surface molecules for entry. Recent progress has shown HIV-l subtype-specific preference for alternative coreceptors, and suggests different target cell p | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF WASHINGTON | $64,380 | Grant | Trans-NIH Recovery Act Research Support: This is an administrative supplment grant request to the NIH to purchase a new ultracentrifuge and rotor. The equipment is to replaced an old instrument that can no longer be serviced. The equipment will be used for purification of proteins, which is a | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $748,705 | Grant | Trans-NIH Recovery Act Research Support: The past several years have seen major progress in the delivery of treatment and care to HIV-infected people in the developing world. However, substantial uncertainty persists regarding optimal treatment strategies, the cost of second- and third-line anti | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE | $33,900 | Grant | Trans-NIH Recovery Act Research Support: Human cytomegalovirus (HCMV) is a beta-herpes virus that can establish persistence and latent infections. HCMV can cause morbidity and mortality in immuno-compromised individuals such as transplant-recipients and HIV-infected persons. In fact, HIV-positiv | Health and Human Services, Department of / National Institutes of Health | 6/11/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $86,976 | Grant | Trans-NIH Recovery Act Research Support: Three undergraduates have all started working on sub-projects relating to a parent R01 award 'APOBEC3 proteins and uracil in retrovirus restriction'. | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $409,000 | Grant | Trans-NIH Recovery Act Research Support: Viruses are potent cancer-inducing agents. While the clinical effects of cancer are obvious, its cellular and molecular causes are not fully understood. Here we propose to study the cellular entry mechanisms of polyomavirus (Py), a non-enveloped DNA tumor | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| CHILDRENS HOSPITAL OF PHILADELPHIA | $234,823 | Grant | Trans-NIH Recovery Act Research Support: Project Summary: The immunological synapse (IS) is the dynamic interface between an immune cell and the cell that it is recognizing. A major function of the IS is directed secretion, which allows specific targeting of immune effector function. Our long-te | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $499,900 | Grant | Trans-NIH Recovery Act Research Support: We request funds to purchase a BD Biosciences FACSAria II high-speed cell sorter. The instrument will be used by investigators studying immune response to viral infection in animal models. Viral pathogens include highly pathogenic influenza including H5N1 | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $39,583 | Grant | Trans-NIH Recovery Act Research Support: This Supplement will provide summer research opportunities for four high school (HS) students and four undergraduate students over two summers. Consistent with ARRA, students will gain experience that can launch careers into biomedical research while prov | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| WASHINGTON UNIVERSITY, THE | $438,699 | Grant | Trans-NIH Recovery Act Research Support: Project ended 1/31/12. ***CLOSEOUT DOCS. SUBMITTED TO NIH 5/21/12*** Upon contact with bone, matrix-derived signals in the RANKL-induced osteoclast (OC) prompt the cell to polarize its cytoskeleton, eventuating in formation of an isolated microenvironme | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| NORTHWESTERN UNIVERSITY | $457,500 | Grant | Trans-NIH Recovery Act Research Support: Systemic sclerosis (SSc) is a devastating condition with no disease-modifying treatment. Fibrosis, the hallmark of SSc, is caused by fibroblast activation with collagen overproduction and myofibroblast differentiation. Transforming growth factor-b (TGF-b) | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| CHILDREN'S RESEARCH INSTITUTE | $224,338 | Grant | Trans-NIH Recovery Act Research Support: This proposal is aimed to achieve 3 broad objectives a) to enhance the tempo of research proposed in the parent grant using enhanced breeding strategies as well as pursuing complementary approaches to the remaining aims of the parent proposal, b) to hire | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF IOWA, THE | $216,051 | Grant | Trans-NIH Recovery Act Research Support: Intervertebral total disc replacement (TDR) implants potentially herald a paradigm shift in the management of degenerative disc disease. Preservation of motion may avoid adjacent-segment degeneration, a well- recognized complication of fusion. Based on en | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $207,542 | Grant | Trans-NIH Recovery Act Research Support: This proposal seeks to determine the feasibility of targeted therapy against the autoantibodies that cause the blistering in this disease. We will screen pharmacological compounds and other small molecules, that could potentially be developed into drugs, | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $64,152 | Grant | Trans-NIH Recovery Act Research Support: This award is an administrative supplement for AR053353, G?Inducing Skeletal Repair Using Mechanical StimulationG?. The overall hypothesis of the parent grant is that functional, hyaline-like cartilage can be formed postnatally via mechano-regulated skel | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| WASHINGTON UNIVERSITY, THE | $34,343 | Grant | Trans-NIH Recovery Act Research Support: Loss of function mutations of the heparan sulfate proteoglycan gene glypican-3 (GPC3), causes an Xlinked disorder in humans known as Simpson Golabi Behmel syndrome (SGBS), a disorder associated with both pre- and postnatal overgrowth, a predisposition to | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC. | $85,280 | Grant | Trans-NIH Recovery Act Research Support: The parent application is focused on determining whether the homeodomain protein Cux1 is a downstream effector of the Notch signaling pathway. Cux1 is the murine homologue of the Drosophila gene Cut. Mammalian Cut proteins function as cell-cycle dependent | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| EMORY UNIVERSITY | $524,750 | Grant | Trans-NIH Recovery Act Research Support: Amongst the greatest risks to human public health is the possibility of large outbreaks of viruses or antibioticresistant bacteria (natural or engineered) occurring with speeds that would not allow the development and timely administration of prophylactic | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF MISSOURI SYSTEM | $416,625 | Grant | Trans-NIH Recovery Act Research Support: Reliable and efficient energy scoring functions are highly needed and vitally important for accurate protein structure prediction, protein and rational therapeutic design. Unfortunately such energy scoring functions still remain at large. In this project | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $91,564 | Grant | Trans-NIH Recovery Act Research Support: This Administrative Supplement under award number R01 CA119079, Mecahnisms of Cell Death After Photodynamic Therapy is being used to purchase a Nikon Ti-E Inverted Microscope with Epi-Fluorescence and Phase Contrast. | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| NEVADA CANCER INSTITUTE | $208,080 | Grant | Trans-NIH Recovery Act Research Support: Melanoma, the most rapidly increasing malignancy in the United States, accounts for only 4% of all skin cancers but is responsible for nearly 80% of skin cancer deaths. If detected early, the disease is easily treated, however, once the disease has metast | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| UNIVERSITY OF UTAH, THE | $338,625 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Avascularity of the cornea is necessary for optical transparency in the visual axis. Vision-threatening corneal angiogenesis can be caused by diseases, aging, infection, or trauma. The basis of the cornea's physiologic | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| WAYNE STATE UNIVERSITY (INC) | $139,392 | Grant | Trans-NIH Recovery Act Research Support: We propose the following specific aims: 1) To access how the TLR-mediated signaling pathways are modulated by the IRAK family of proteins and Pik/AKT and what roles they play in acquiring tolerance phenotype in HCECs. This will be achieved by using siRNA | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF WASHINGTON | $176,068 | Grant | Trans-NIH Recovery Act Research Support: We are requesting supplemental funds to employ a new graduate student to carry out studies that will accelerate our scientific progress on our funded proposal. The overall goal of the funded proposal is to determine whether the Muller glia of the mammalia | Health and Human Services, Department of / National Institutes of Health | 8/19/2009 |
| CHILDREN'S HOSPITAL CORPORATION, THE | $249,027 | Grant | Trans-NIH Recovery Act Research Support: Our long-term research goal is to understand oculomotor development and the pathogenesis of congenital ocular motor diseases. We address this goal through genetic and neurodevelopmental studies of complex congenital eye movement disorders and their mutate | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $96,336 | Grant | Trans-NIH Recovery Act Research Support: We are addressing the physiology of aqueous humor outflow regulation, concentratingon cell volume regulatory transporters and adenosine receptors of Schlemms canal,juxtacanalicular and trabecular meshwork cells, and on the potential role of cell volumein | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $154,015 | Grant | Trans-NIH Recovery Act Research Support: Visual scenes contain too much information to be perceived in a single glance. Natural visual tasks G?? reading, search, evaluating a scene G?? depend critically on sequential examination by saccadic eye movements and shifts of attention. Saccades are e | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $177,568 | Grant | Trans-NIH Recovery Act Research Support: The overarching study was initiated because the adverse neural consequences of abnormal vision have been well researched, but under-detection of risk factors for amblyopia is still common. Gaps in screening in the medical home are due to children missing | Health and Human Services, Department of / National Institutes of Health | 8/19/2009 |
| DUKE UNIVERSITY | $126,958 | Grant | Trans-NIH Recovery Act Research Support: Impairments in visual-auditory integration impact numerous aspects of human health, ranging from communication and language to attention and movements in a complicated environment. Previously, such deficits were believed to involve higher brain structures | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF ROCHESTER | $99,999 | Grant | Trans-NIH Recovery Act Research Support: Our goal is to acquire an MR-compatible visual display set-up that has an integrated eye-tracker. Our experiments require mapping brain systems that mediate attention and visual short-term memory and how these systems change as a function of the experi | Health and Human Services, Department of / National Institutes of Health | 8/19/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE | $338,506 | Grant | Trans-NIH Recovery Act Research Support: Corneal wound healing without scarring regenerates corneal transparency. Corneas that heal with scarring have opacities and obstructed vision. Thus, understanding the pathways that influence regenerative rather than fibrotic healing is an essential step t | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $148,175 | Grant | Trans-NIH Recovery Act Research Support: Quarterly Report for ARRA Supplement Sensory-Motor Control of the Binocular Near Response PI: Clifton M. Schor Overall purpose and expected outcomes, or results of the contract: The supplement investigates the impact of neural deblurring on accommodati | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| NATIONAL JEWISH HEALTH | $124,809 | Grant | Trans-NIH Recovery Act Research Support: We recently described a novel protein, Growth Inhibition and Death E3 Ligase (GIDE), a mitochondrially located E3 ubiquitin ligase. GIDE contains a C-terminal RING finger domain, which is similar in sequence to that of Inhibitor of Apoptosis Proteins (IA | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| UNIVERSITY OF PITTSBURGH THE | $151,448 | Grant | Trans-NIH Recovery Act Research Support: Under the aegis of the parental award R01CA108990 Multianalyte assay for early diagnosis of ovarian cancer, we have identified and validated a 4-biomarker panel that recognizes early stages (I-IIB) ovarian cancer with high sensitivity of 86% at 98% specif | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| DUKE UNIVERSITY | $150,547 | Grant | Trans-NIH Recovery Act Research Support: The ultimate goal of this proposal is to identify biomarkers that can determine which patients presenting with non-small cell lung cancer (NSCLC) have metastasis. While some patients present with overt metastatic disease, others may have more subtle metas | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| BAYLOR COLLEGE OF MEDICINE | $286,225 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this award is to create new job and accelerate our research on SRC-1 and breast cancer. Our first task is to use the budget to hire a cancer research scientist with a citizenship of United States who will lose his job in August of 2009 due | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $540,890 | Grant | Trans-NIH Recovery Act Research Support: Re-activation of maspin tumor suppressor gene by designed transcription factors The overall purpose of this project is to develop novel delivery systems to introduce an Artificial Transcription Factor with anti-metastatic activity into primary breast tumo | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| THE VANDERBILT UNIVERSITY | $19,729 | Grant | Trans-NIH Recovery Act Research Support: The immediate goal of this three month project is to purify a fragment (60kDa) of the EGF receptor that is generated when cells are treated with EGF. The fragment is generated by rhomboid proteases, which cleave transmembrane proteins within the transmemb | Health and Human Services, Department of / National Institutes of Health | 6/03/2009 |
| BROAD INSTITUTE, INC., THE | $193,330 | Grant | Trans-NIH Recovery Act Research Support: We propose to accelerate the application and validation of the PEPPeR platform to biomarker discovery using lung tissue interstitial fluid (TIF) for discovering biomarkers in lung adenocarcinoma. A relatively large set of 20 TIF samples (10 control and 10 | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| NORTHWESTERN UNIVERSITY | $206,270 | Grant | Trans-NIH Recovery Act Research Support: This supplement application is requesting funding to construct an EEG lab at the main facilities in the downtown Chicago campus. This will increase the efficiency in scheduling and recruitment and speed up the research program. | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| UNIVERISTY OF MISSISSIPPI MEDICAL CENTER | $48,000 | Grant | Trans-NIH Recovery Act Research Support: The EQ supplement is to request funds to purchase three pieces of data acquisition equipment (Bak electronics for single unit recording, CED device for high speed data acquisition and Digitimer D360 to record 8-channel event-evoked potentials). With this | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $497,679 | Grant | Trans-NIH Recovery Act Research Support: Little is known about the developmental mechanisms that determine kidney size and nephron number. Two major renal cell lineages are collecting ducts, which derive from ureteric bud (UB), and nephron epithelia, which derive from metanephric mesenchyme (M | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY | $30,305 | Grant | Trans-NIH Recovery Act Research Support: Congenital defects characterized by impaired urine flow from the kidney into the lower urinary tract are detected in 0.5% of fetuses by antenatal screening and if persistent, can lead to permanent renal damage. Despite the high incidence and morbidity of | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $150,063 | Grant | Trans-NIH Recovery Act Research Support: ARRA - Nitric Oxide-Releasing Glucose Biosensors To fully realize our goal of understanding the influence of nitric oxide release and duration on improved tissue biocompatibility (and ultimate the fabrication and characterization of a nitric oxide-releas | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| CASE WESTERN RESERVE UNIVERSITY | $185,411 | Grant | Trans-NIH Recovery Act Research Support: The goal of this research is to develop and clinically implement a new method of quickly and reversibly blocking the conduction of action potentials in peripheral nerve. In our currently funded project, we have demonstrated that high frequency alternating | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF FLORIDA | $334,264 | Grant | Trans-NIH Recovery Act Research Support: Approximately 50-70% of patients with chronic pain, particularly fibromyalgia sufferers, report sleep difficulties. Because it is not possible to randomly induce chronic pain or chronic insomnia in otherwise healthy participants, the exact nature of the s | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $1,372,153 | Grant | Trans-NIH Recovery Act Research Support: Osteoarthritis (OA) affects 27 million Americans, many of whom have concomitant symptomatic meniscal tear. Arthroscopic partial meniscectomy (APM) is the surgical procedure used to treat these patients when conservative measures are not successful. The ef | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| ST. JUDE CHILDREN'S RESEARCH HOSPITAL | $175,000 | Grant | Trans-NIH Recovery Act Research Support: The innate immune system comprises several classes of pattern recognition receptors, including Toll- like receptors (TLRs), NOD-like receptors (NLRs), and RIG-1-like receptors (RLRs). TLRs recognize microbes on the cell surface and in endosomes, whereas N | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF CINCINNATI | $31,382 | Grant | Trans-NIH Recovery Act Research Support: Merlin is the product of the neurofibromatosis type 2 (NF2) gene. In humans, loss of merlin is associated with the development of a variety of tumors including schwannomas, meningiomas, ependymomas and mesotheliomas. That both NF2 alleles must be inactiva | Health and Human Services, Department of / National Institutes of Health | 6/02/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $132,791 | Grant | Trans-NIH Recovery Act Research Support: It is widely accepted that the p53 tumor suppressor restricts abnormal or DNA damage-exposed cells before damage to DNA is converted to inherited mutation by induction of growth arrest or by triggering apoptosis. This process depends mainly on the express | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| TRUSTEES OF PRINCETON UNIVERSITY, THE | $172,564 | Grant | Trans-NIH Recovery Act Research Support: Human cytomegalovirus (HCMV) is the prototypical member of the beta-herpesvirus family. Epidemiological studies have shown that HCMV infection is widespread. In healthy individuals infection is generally asymptomatic, but the virus can cause serious disea | Health and Human Services, Department of / National Institutes of Health | 8/27/2009 |
| UNIVERSITY OF CHICAGO, THE | $351,782 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this investigation is to determine the molecular distinctions between estrogen agonism and antagonism in hormone dependent tissues and cancers and to use this information to develop and characterize novel compounds that can be used for | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $578,244 | Grant | Trans-NIH Recovery Act Research Support: Chromosomal translocations are highly associated with cancer development. Both Nbs1 (Nijmegen breakage syndrome) and Mrell (ataxia-telangiectasia-like disorder) deficient patients exhibit increased levels of chromosomal translocations and higher risk of d | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $129,973 | Grant | Trans-NIH Recovery Act Research Support: In this supplement, we will test the predictive role of two amplification events and gene fusion status in alveolar rhabdomyosarcoma by testing samples from a single clinical trial. This study will involve applying our assays for amplification and gene fu | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF TEXAS M D ANDERSON | $308,000 | Grant | Trans-NIH Recovery Act Research Support: Cancer predisposition syndromes are autosomal dominantly inherited conditions in which the affected individuals have a high relative risk for developing cancer. PTEN and neurofibromatosis-2 (NF2) are tumor suppressors that are inactivated in both somatic | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| FRED HUTCHINSON CANCER RESEARCH CENTER | $171,212 | Grant | Trans-NIH Recovery Act Research Support: We aim to utilize expression microarrays to define gene expression profiles in a large cohort of FLT3/ITD AML patients who relapsed and contrast them to the expression signature in patients in long term remission. Funds from this administrative supplemen | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $765,494 | Grant | Trans-NIH Recovery Act Research Support: Cancer is one of the leading health disorders that can lead to impaired functioning and mortality in the elderly. During the cancer survivorship period, a patients' symptoms may go unrecognized or be poorly managed. Family involvement in care provision me | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $264,075 | Grant | Trans-NIH Recovery Act Research Support: This award, issued under the American Recovery and Reinvestment Act of 2009, is a supplement to my NCI supported grant entitled G? Mechanistic Analysis of Papillomavirus E2 FunctionsG?. The human papillomaviruses are associated with a number of human canc | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| UNIVERSITY OF LOUISVILLE | $99,268 | Grant | Trans-NIH Recovery Act Research Support: The HPLC system requested is to measure the fate of chemopreventive agents delivered via dietary route or systemic route by measuring the plasma or tissue levels of the compounds to understand the mechanism and allow identification of their metabolites. | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $413,741 | Grant | Trans-NIH Recovery Act Research Support: We have employed two post-doctoral fellows, one with a background in physics and one with a background in mechanical engineering to accelerate the realization of the dual-panel breast-dedicated PET system proposed by the parent project. Since the project | Health and Human Services, Department of / National Institutes of Health | 9/08/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $344,729 | Grant | Trans-NIH Recovery Act Research Support: This supplemental request complements the parent grant in that the supplement proposes to create a CRAd that has greater oncolytic potency than the CRAd that was previously considered for imaging modification in the parent grant. The oncolytic potency of | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| LOUISIANA STATE UNIVERSITY SYSTEM | $443,635 | Grant | Trans-NIH Recovery Act Research Support: Human papillomavirus (HPV) infection of anogenital tissues has been implicated as a requisite step in the progression to neoplastic transformation. The role of HPV in cervical cancer has been well elucidated; however, most infections with HPV do not lead | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| VIRGINIA COMMONWEALTH UNIVERSITY | $344,973 | Grant | Trans-NIH Recovery Act Research Support: We are exploring a set of questions within the scope of the parent grant. The first concerns single women insured through their own employer - women who do not have the option of relying on a spouse as an alternative source of health insurance. Second, we | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $155,568 | Grant | Trans-NIH Recovery Act Research Support: By some estimates, 50% of the 56,000 US colo-rectal cancer (CRC) deaths per year in the US could be prevented by appropriate, risk-based CRC testing. Hispanics have lower incidence and mortality from CRC, but are typically diagnosed at later stages and h | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $494,183 | Grant | Trans-NIH Recovery Act Research Support: In the present proposal, our preliminary data demonstrates that beta1 integrin inhibition enhances the therapeutic efficacy of IR in vivo; these promising findings have the potential to impact clinical RT for patients. We hypothesize that beta1 integrin m | Health and Human Services, Department of / National Institutes of Health | 9/08/2009 |
| UNIVERSITY OF RHODE ISLAND | $297,136 | Grant | Trans-NIH Recovery Act Research Support: The broad objectives of this research project are to develop effective intervention methods for long-term maintenance of healthy lifestyle behaviors (exercise and diet) in older adults to improve their health status and quality of life. The specific aims | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| RESEARCH TRIANGLE INSTITUTE | $367,320 | Grant | Trans-NIH Recovery Act Research Support: The supplemental funding will be used to accelerate development of a dedicated dissemination Web site to provide the health research community with easy access to a variety of geospatial databases being developed under the parent NIH-funded research progr | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $296,245 | Grant | Trans-NIH Recovery Act Research Support: Breast cancer is a disease for which personalized risk prediction could vastly improve care. Our currently funded R01 has enabled us to develop an algorithm called view learning that integrates predictive data from a complex multi-relational mammography | Health and Human Services, Department of / National Institutes of Health | 9/08/2009 |
| PENNSYLVANIA STATE UNIVERSITY, THE | $38,411 | Grant | Trans-NIH Recovery Act Research Support: We have completed analysis of over 250 lung cancer samples by a high- resolution genome profiling method developed here at Cold Spring Harbor Laboratory (CSHL). We found twelve major recurrent amplicons, most of which contain known driver genes such as MY | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| CREIGHTON UNIVERSITY | $623,249 | Grant | Trans-NIH Recovery Act Research Support: Vitamin D, as measured by serum 25(OH)D, is prevalently low in older people, and more than 60% of North American female populations are below the optimal level. Low vitamin D is a serious problem since optimal serum 25(OH)D concentration is essential for | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| RENSSELAER POLYTECHNIC INSTITUTE | $90,000 | Grant | Trans-NIH Recovery Act Research Support: There is a very large unmet therapeutic need to treat humans that abuse illegal drugs, especially cocaine. To address this unmet need, this application is focused on the design, synthesis and pharmacological characterization of potential anti-cocaine medi | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| MAYO CLINIC | $80,000 | Grant | Trans-NIH Recovery Act Research Support: This grant provided a summer research experience for 19 science teachers in health-related scientific research. | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| NATIONAL DEVELOPMENT AND RESEARCH INSTITUTES, INC. | $183,352 | Grant | Trans-NIH Recovery Act Research Support: In the parent project to this competitive revision application, we are currently evaluating the comparative effectiveness and cost-effectiveness of a web-based psychosocial treatment intervention with individuals in methadone maintenance treatment (relati | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $42,820 | Grant | Trans-NIH Recovery Act Research Support: It has recently been discovered that glia become progressively more activated upon repeated exposure to morphine, & that this glial activation, in turn, modulates morphine's effects. This discovery was originally made in the context of studying the pain s | Health and Human Services, Department of / National Institutes of Health | 6/20/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $567,200 | Grant | Trans-NIH Recovery Act Research Support: This Competitive Revision enhances medication development for treatment of cocaine dependence by expanding the scope of a study evaluating the efficacy of a pharmacotherapy (D-cycloserine) in facilitating extinction to cocaine-related cue reactivity. In t | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $137,625 | Grant | Trans-NIH Recovery Act Research Support: The focus of this research is cochlear hearing loss and its effects on the perception of simple and complex sounds and the ability to understand speech. Hearing loss is one of the most common chronic conditions of aging and contributes to poor communicat | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | $117,654 | Grant | Trans-NIH Recovery Act Research Support: In this supplement application, we propose two studies that expand two specific aims in the parent grant in directions that will form a foundation for a new R01 grant focusing on learning and treatment processes in aphasia. In each study, we will use | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $248,880 | Grant | Trans-NIH Recovery Act Research Support: Disruption of vestibular signals from one labyrinth results in asymmetries in the angular vestibuloocular reflex (VOR) evoked by high-frequency, high-acceleration head movements. Studies during the previous funding period have elucidated linear and nonlin | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF KENTUCKY | $153,308 | Grant | Trans-NIH Recovery Act Research Support: The mammalian olfactory epithelium does two remarkable things with its olfactory sensory neurons. These neurons detect odorants, translating the structure of volatile chemicals into a neural information code, and the epithelium can replace these neurons e | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| MONELL CHEMICAL SENSES CENTER | $543,211 | Grant | Trans-NIH Recovery Act Research Support: During the past few years my laboratory has explored the involvement of taste signaling elements in gastrointestinal (GI) chemosensation. In particular, how macronutrients in the gut lumen are sensed and in turn regulate hormone release from specific ente | Health and Human Services, Department of / National Institutes of Health | 7/31/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $246,636 | Grant | Trans-NIH Recovery Act Research Support: The goals of this study are to demonstrate and confirm the role of genetic factors in the development of chronic otitis media with effusion and recurrent otitis media (COME/ROM) to improve understanding of its underlying biological and pathological mechan | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $321,877 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Normal vocal fold vibration is crucially dependent upon tissue composition and viscoelasticity. When composition of the extracellular matrix (ECM) of the vocal fold cover (i.e., lamina propria) is altered, vocal fold v | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |