Listing all stimulus spending by amount, in descending order. Return to National Institutes of Health page
Amount refers to both the amount of stimulus funding going toward the project and the face value of the loan.
| Recipient | Amount | Type | Description | Federal Dept./Agency | Date |
|---|---|---|---|---|---|
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $140,294 | Grant | Trans-NIH Recovery Act Research Support: Otitis media (middle ear inflammation) is one of the most common childhood diseases. The prevalence, medical costs, and hearing related morbidity of otitis media (OM) are significant. Streptococcus pneumoniae (Spn) is one of the primary pathogens of OM. D | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF IOWA, THE | $470,431 | Grant | Trans-NIH Recovery Act Research Support: While previous studies have shown that children with mild-to-severe hearing loss are at risk for poorer language, academic, social and psychological outcomes, these studies were conducted prior to the implementation of universal newborn hearing screening | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $742,279 | Grant | Trans-NIH Recovery Act Research Support: The primary aim of the proposed research is to develop a miniature microphone diaphragm for hearing aids that achieves second-order directional sensitivity to sound over the frequency range that is important for speech. A hearing aid that can achieve seco | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| TEXAS A & M UNIVERSITY SYSTEM HEALTH SCIENCE CENTER RESEARCH | $14,650 | Grant | Trans-NIH Recovery Act Research Support: This supplement to parent grant 3R01DE005092 funded the hiring of two full-time graduates during the summer prior to their entry into the freshman year of the DDS program at Baylor College of Dentistry. The two graduates will be able to gain short-term r | Health and Human Services, Department of / National Institutes of Health | 6/15/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $617,681 | Grant | Trans-NIH Recovery Act Research Support: Osteoclasts are large, multinucleated cells that play a central role in bone resorption. They are derived from hematopoietic precursors in response to RANKL. RANKL is both necessary and sufficient for osteoclastogenesis, although factors such as M-CSF, TG | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| UNIVERSITY OF ROCHESTER | $98,211 | Grant | Trans-NIH Recovery Act Research Support: This grant is focused on mouse models of slow onset outlet obstruction that results from slow anatomical changes in the mouse lower urinary tract. This supplement provides supplies and personnel support that will enhance our image analysis and computer pr | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $25,491 | Grant | Trans-NIH Recovery Act Research Support: This grant provided summer research experiences for two college students in health?related scientific research. There were no significant changes from the project abstract as it appears in the proposal. The two students who worked in the lab were Robert | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $47,850 | Grant | Trans-NIH Recovery Act Research Support: Leukocyte accumulation is the hallmark of inflammatory renal diseases. TNF, a potent cytokine that regulates leukocyte trafficking, is essential for the development of glomerulonephritis (GN) in animal models. The biological activities of TNF are mediated | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The solution and redox properties of iron that make it the metal prosthetic group of choice for the activation of otherwise kinetically inert substrates, including dioxygen, also make ionic Fe cytotoxic to aerobic organisms. Eukaryotes from yeast to human | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| THE CHILDREN'S HOSPITAL OF PHILADELPHIA | $820,936 | Grant | Trans-NIH Recovery Act Research Support: This is a competitive supplement in response to NOT-OD-09-058 (NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications). Diabetes is a metabolic disorder that currently affects over 180 million people worldwide. Common t | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF HAWAII SYSTEMS | $128,111 | Grant | Trans-NIH Recovery Act Research Support: Less than a fourth of ethnic minority teens in the U.S. are a designated donor (DD) on their state-issued driver's license. Asian-American/Pacific Islander (AA/PI) adolescents in Hawaii are even less likely to be a DD or to have talked to their family abo | Health and Human Services, Department of / National Institutes of Health | 8/29/2009 |
| CHILDREN'S RESEARCH INSTITUTE | $39,216 | Grant | Trans-NIH Recovery Act Research Support: This supplement funds 2 summer undergraduate students to work full-time on the parent R01, Parenting among Young Children with Type 1 Diabetes, over the 3 summer months, for 2 summers. The deliverables are hired students working the hours, and contributin | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $566,265 | Grant | Trans-NIH Recovery Act Research Support: This competitive revision grant proposes to identify novel peptide inhibitors for the digestive enzyme chymotrypsin C. The parent grant investigates how chymotrypsin C regulates activation and degradation of other digestive enzymes and how mutations in ch | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $175,049 | Grant | Trans-NIH Recovery Act Research Support: Chronic viral infections afflict more than 500 million people worldwide. Loss of T cell function has been noticed for long time during persistent viral infections but the underlying factors are not completely understood. By using in vivo chronic lymphocyt | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| HENRY M JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY M | $61,200 | Grant | Trans-NIH Recovery Act Research Support: An administrative supplement for the purpose of purchasing a novel knockout mouse strain from Lexicon Genetics | Health and Human Services, Department of / National Institutes of Health | 7/23/2009 |
| MAYO CLINIC | $71,395 | Grant | Trans-NIH Recovery Act Research Support: This supplement request pertains to the activities approved under Aim 1 of RO1 AR48147. The central hypothesis of the parent grant is that Hdac3 and Hdac7 are essential components of a multi-protein complex that regulates Runx2 activity. The objective of | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $384,258 | Grant | Trans-NIH Recovery Act Research Support: BMP-3 Signaling in the Formation and Regulation of Bone: The long-term goals of this project are to gain insights into the mechanisms by which BMP3 regulates osteogenesis. Although research on bone morphogenetic proteins (BMPs) has expanded exponentially | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| THOMAS JEFFERSON UNIVERSITY | $193,125 | Grant | Trans-NIH Recovery Act Research Support: Our Preliminary Data show that hypertrophic chondrocytes do in fact express CHOP, an important UPR target protein that has a prominent role in ER stress-induced apoptosis. We found also that pre-hypertrophic chondrocytes express Bip, a chaperon protein th | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $1,389,712 | Grant | Trans-NIH Recovery Act Research Support: The goals of this award New Faculty Development for Research to Reduce Oral Heal (NIH/NIDCR P30 DE020752) are to appoint independent, tenure-track equivalent research intensive Assistant Professors at the UCSF School of Dentistry along with Research Assis | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $288,245 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the UCSF Liver Center is to help scientists perform better research at a faster pace and place them in a position for individual research support by NIH/NIDDK. To achieve its goals, the Center provides three types of benefits: (1) research | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| THE WASHINGTON UNIVERSITY | $174,400 | Grant | Trans-NIH Recovery Act Research Support: The exact pathogenesis of arthritis in children or adults is not known, but several cells contribute to the development of autoimmune arthritis including T and B lymphocytes, synovial cells, macrophages, neutrophils and osteoclasts (OC) [1-3]. Identifying | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $94,190 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this award is to replace aging and malfunctioning equipment needed for research on type II topoisomerases, essential enzymes that serve as targets for a variety of clinically-established therapeutics. The primary purchases made from this s | Health and Human Services, Department of / National Institutes of Health | 8/27/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $178,357 | Grant | Trans-NIH Recovery Act Research Support: In response to NIH NOT-OD-09-058 titled NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications, we wish to extend studies spearheaded during the funding of NIH grant 2R01 CA78747 titled Enediyne Biosynthesis and Enginee | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $163,485 | Grant | Trans-NIH Recovery Act Research Support: To investigate the role of melatonin, tea drinking, one-carbon metabolites and other dietary agents in the development and potential prevention of breast cancer in women. | Health and Human Services, Department of / National Institutes of Health | 9/20/2009 |
| EMORY UNIVERSITY | $643,253 | Grant | Trans-NIH Recovery Act Research Support: Free radicals that are made from oxygen have recently been found to be overproduced in several types of cancers, including those of the digestive tract. The major source of these radicals has recently been discovered to be a type of enzyme called a G?NoxG | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $151,496 | Grant | Trans-NIH Recovery Act Research Support: The checkpoint kinase Chk1 is the first line of defense against DNA damage and is involved in the establishment of the cell cycle arrest in response to DNA damage. It is proposed that during S phase the damaged DNA is sensed and the repair proteins are r | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| THE UNIVERSITY OF SOUTH DAKOTA | $32,111 | Grant | Trans-NIH Recovery Act Research Support: Drug addiction is a chronic and relapsing disorder. Drug relapse is thought to arise, in part, from the need to alleviate negative withdrawal symptoms such as anxiety, depression, and increased stress sensitivity. The goal of this research is to underst | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| CHILDREN'S RESEARCH INSTITUTE | $347,777 | Grant | Trans-NIH Recovery Act Research Support: This ARRA funding is an NIH award to support scientific research, specifically the study of development of the amygdala of the rodent brain. The mammalian amygdala is a central structure of the brain's limbic system, a brain circuit that coordinates appr | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $1,059,107 | Grant | Trans-NIH Recovery Act Research Support: Treatment for substance use disorders generally consists of relatively brief episodes of care that do not properly address the chronic, relapsing nature of these disorders. In the parent grant and other prior work, we have developed a telephone based con | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $91,257 | Grant | Trans-NIH Recovery Act Research Support: A more thorough characterization of how costimulatory receptors and cytokines regulate the metabolic brprocesses of lipid and nucleotide biosynthesis is being undertaken in these studies. It is believed these brinsights may lead to the development of nov | Health and Human Services, Department of / National Institutes of Health | 9/02/2009 |
| UNIVERSITY SYSTEM OF NEW HAMPSHIRE | $204,879 | Grant | Trans-NIH Recovery Act Research Support: In the parent project, we are developing a second generation of cross-bridged macrocyclic ligands (chelators) for copper-, indium- and gallium-based radiopharmaceuticals for diagnostic imaging and targeted radiotherapy of cancer. We are designing pendant- | Health and Human Services, Department of / National Institutes of Health | 9/08/2009 |
| THE VANDERBILT UNIVERSITY | $130,472 | Grant | Trans-NIH Recovery Act Research Support: Studies of human and mouse prostate cancer indicate that the homeodomain-containing transcription factor Nkx3.1 is an important haplo-insufficient tumor suppressor gene involved in prostate tumor initiation. Nkx3.1 protein expression is lost in human and | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $8,030 | Grant | Trans-NIH Recovery Act Research Support: This grant provided summer research experiences for two undergraduate college students from UAB and Duke Universities to do health-related leukemia and stem cell research. | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $48,380 | Grant | Trans-NIH Recovery Act Research Support: The ubiquitin proteasome pathway regulates an astounding array of cellular events and remains essential throughout the life cycle of a cell; its dysfunction is associated with ailments as threatening as cancer and neurodegenerative diseases. The pathway f | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $281,370 | Grant | Trans-NIH Recovery Act Research Support: Huntingtin Interacting Protein 1 (HIP1) is a clathrin, actin and inositol lipid binding protein that has been implicated in neurodegeneration by virtue of its interaction with huntingtin, the protein mutated in Huntington's disease. It is also associated | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| THE VANDERBILT UNIVERSITY | $385,325 | Grant | Trans-NIH Recovery Act Research Support: The Nashville Breast Health Study (NBHS, R01CA100374).is a population-based, case-control study of breast cancer funded by NCI since June 2004 with a major focus on evaluating genetic factors and gene environment interactions involved in the etiology of b | Health and Human Services, Department of / National Institutes of Health | 9/20/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $299,698 | Grant | Trans-NIH Recovery Act Research Support: Adoptive transfer of TCR gene modified T cells represents a novel new approach for treating patients with various malignanicies. The goal parent NIH R01 grant, CA104947-03 entitled ?TCR Affinity and Therapeutic Efficacy of T Cells? is to determine how TC | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $234,019 | Grant | Trans-NIH Recovery Act Research Support: The overall scientific purpose of the award was to isolate and characterize aggressive and nonaggressive human pancreatic tumor cells. We expect that highly valuable cell variants will be characterized and that potential therapeutic targets for pancreatic | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $99,219 | Grant | Trans-NIH Recovery Act Research Support: The microbes that inhabit human bodies outnumber the human cells by an order of magnitude, and impact many aspects of health and disease including obesity, vaginosis, and Crohn's disease. Understanding this endogenous microbiota is emerging as a key exten | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF PITTSBURGH THE | $143,613 | Grant | Trans-NIH Recovery Act Research Support: This study is aimed at developing in vivo targeted vaccine for tumor immunotherapy by testing whether Aghsp70 proteins improve DC functions and strong and sustained Ag-specific-T cell responses can be induced by the in vivo prolongation of Aghsp70-bearing | Health and Human Services, Department of / National Institutes of Health | 9/08/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $21,641 | Grant | Trans-NIH Recovery Act Research Support: Summer undergraduate research experience in the design and study of monosaccharide analogs, sialic acid metabolism, and apoptosis | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $54,840 | Grant | Trans-NIH Recovery Act Research Support: Colorectal cancer (CRC) is the third leading type of cancer and the third leading cause of cancer death in the United States. Ohio has higher than average rates of CRC mortality. Our study population will also include minority and older individuals as the | Health and Human Services, Department of / National Institutes of Health | 6/02/2009 |
| UNIVERSITY OF WASHINGTON | $115,481 | Grant | Trans-NIH Recovery Act Research Support: The long-term objective of this research is to help eliminate the suffering and death of children with brain cancer. Brain cancers are the most common solid tumors in children. Survival remains poor for patients with metastases or recurrence; current ther | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| WAKE FOREST UNIVERSITY | $74,000 | Grant | Trans-NIH Recovery Act Research Support: Every year as many as 200,000 patients receive whole brain irradiation (WBI). Most of these patients are treated not for primary brain tumors, but for brain metastases from melanomas, breast cancer or lung cancer that increase in middle age. As patient su | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $304,163 | Grant | Trans-NIH Recovery Act Research Support: Although the prototypes of breast cancer suppressor genes, BRCA1 and BRCA2, have been identified, the genetic defects responsible for the majority of breast cancer remain elusive. In addition, essentially all cancer suppressor genes identified are autosom | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $346,579 | Grant | Trans-NIH Recovery Act Research Support: Biologic evidence indicates that the repair of ultraviolet-induced DNA damage plays a critical role in protecting against melanoma; however, epidemiologic data are limited due to a limited number of genes and polymorphisms examined in initial studies with | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY | $569,049 | Grant | Trans-NIH Recovery Act Research Support: The main approach outlined in the original application was to enhance the specificity of tumor targeting by designing mechanisms to amplify the targeting. We believe that this is still an approach unique to us in the nanobiotechnology research arena. This | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The major objectives of this application are to: (i) functionally characterize a signal transduction pathway linking ATM (ataxia-telangiectasia-mutated) to the cyclic AMP response element-binding protein (CREB) transcription factor; and (ii) identify and | Health and Human Services, Department of / National Institutes of Health | 9/02/2009 |
| UNIVERSITY OF TEXAS M D ANDERSON | $568,179 | Grant | Trans-NIH Recovery Act Research Support: The studies address the problem of relapse of B-lineage acute lymphoblastic leukemia (B-ALL) after umbilical cord blood transplant (UCBT). We hypothesize that the incidence of relapse following allogeneic UCBT can be reduced by targeting post-transplant m | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| COLLEGE OF WILLIAM & MARY, THE | $187,282 | Grant | Trans-NIH Recovery Act Research Support: This supplemental funding to an existing non-ARRA grant, will allow the PI to continue to test his signal processing tools on more data sets associated with this project in order to gather more statistics to improve data normalization and biomarker identi | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF CHICAGO, THE | $186,827 | Grant | Trans-NIH Recovery Act Research Support: Lung cancer is a devastating illness with a poor overall survival. In order to dramatically impact on this disease, new targets and mechanisms have to be identified. One hallmark of lung cancer is enhanced cell motility, migration, invasion and early meta | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| UNIVERSITY OF WASHINGTON | $274,911 | Grant | Trans-NIH Recovery Act Research Support: We now apply for an Administrative Supplement to obtain such funding for each of 2 years, to obtain additional clinical material from Dr Swisher which is needed to evaluate mesothelin as a biomarker for immunodiagnosis and monitoring of patients with ovar | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| DREXEL UNIVERSITY | $304,762 | Grant | Trans-NIH Recovery Act Research Support: The ultimate goal of this request for support for the re-entry of a scientist is for the re-entering candidate to establish an effective and successful independent research program, in less than 2 years, while accelerating the pace of accomplishment of th | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $177,600 | Grant | Trans-NIH Recovery Act Research Support: Neurotransmitters are secreted by neurons and relay messages to target cells on a subsecond time scale. This proposal is directed at real-time monitoring of a specific neurotransmitter, dopamine (DA), in the brain of behaving rats. The sensing technology | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF KENTUCKY | $1,027,710 | Grant | Trans-NIH Recovery Act Research Support: This Competitive Revision Application is in response to Notice Number: NOT-OD-09-058 and Notice Title: NIH Announces the Availability of Recovery Act Funds and is proposed as a competitive supplement to our current R01 grant DA 13519, titled 'Development | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF NEW ORLEANS | $33,408 | Grant | Trans-NIH Recovery Act Research Support: This supplement supports two undergradute students to work in the lab. It will expose these students to ongoing NIDA funded research and will encourge students to pursue seriously reasearch careers in drug abuse. | Health and Human Services, Department of / National Institutes of Health | 6/20/2009 |
| RHODE ISLAND HOSPITAL | $80,000 | Grant | Trans-NIH Recovery Act Research Support: The scope of this supplement is to provide for unique research opportunities and summer employment of college students and faculty from the Division of Chemical Dependency and Addiction Studies at Rhode Island College. These opportunities will provide the | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| PENNSYLVANIA STATE UNIVERSITY, THE | $90,749 | Grant | Trans-NIH Recovery Act Research Support: Obesity is a national epidemic. Among other maladies, obesity underlays most type 2 diabetes and a significant proportion of hypertension. Obesity occurs because individuals ingest more calories than they expend. This takes place when the reward value of | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY | $145,806 | Grant | Trans-NIH Recovery Act Research Support: This research is directed toward improved speech reception for hearing impaired persons and cochlear implantees through a program of research on models of speech intelligibility. The goal is to develop and experimentally evaluate a robust physical metric | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $172,416 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this collaborative research supplement is to provide support for a new interdisciplinary collaboration between two laboratories in different departments at MUSC. Dr. Lisa Cunningham is a neuroscientist in the Department of Pathology and La | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF PITTSBURGH THE | $88,575 | Grant | Trans-NIH Recovery Act Research Support: One of the major goals of the parent grant is to study the effect of synaptic plasticity in the output of the dorsal cochlear nucleus. The parent grant is solely based on classic electrophysiological single and paired recordings. An ideal approach to work | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| STOWERS INSTITUTE FOR MEDICAL RESEARCH | $229,983 | Grant | Trans-NIH Recovery Act Research Support: Funds from this supplemental application will support one additional specialist to accelerate the pace of discovery and allow the upgrade of our existing equipment. | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| SOUTH CAROLINA RESEARCH FOUNDATION | $152,202 | Grant | Trans-NIH Recovery Act Research Support: NEURAL PREDICTORS OF ANOMIA RECOVERY IN APHASIA This project will investigate the relation between neurophysiology and anomia recovery in aphasia following stroke. Stroke is the leading cause of disability in the United States, with an increasing number o | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| SOUTHERN ILLINOIS UNIVERSITY | $274,527 | Grant | Trans-NIH Recovery Act Research Support: This ARRA supplement funded a combined request for 1) an equipment supplement (EQ) to accelerate the tempo of our research under our current parent grant RO1 DC008412-01A1 NIH/NIDCD Title: R01 DC008412-01A1 NIH/NIDCD Developing D-methionine as an Aminogl | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| MASSACHUSETTS EYE AND EAR INFIRMARY & PHYSICIAN STAFF, INC. | $18,910 | Grant | Trans-NIH Recovery Act Research Support: Basic and Clinical Studies of Noise-Induced and Age-Related Hearing Loss The goal of the student summer project proposed here is to assess the dynamics of noise-induced damage to inner hair cell G?? afferent terminals in the acute post-exposure period. | Health and Human Services, Department of / National Institutes of Health | 6/30/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $399,886 | Grant | Trans-NIH Recovery Act Research Support: This project is part of NOT-OD-09-058, with Notice Title, 'NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications' and is consistent with the aims of parent grant DE06988 which seeks to determine if amelogenin proteins | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $16,936 | Grant | Trans-NIH Recovery Act Research Support: The University of Alabama at Birmingham (UAB) is one of America's premier research universities, ranking among the top 20 in funding from the National Institutes of Health and earning more than $360 million per year in contract and grant support, with mor | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $317,047 | Grant | Trans-NIH Recovery Act Research Support: This proposal is based on the perceived need for the design and development of new biomaterials that will be utilized in repair and regeneration of tooth enamel. The major objective of our proposed study is to elucidate the molecular mechanisms involved i | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $32,893 | Grant | Trans-NIH Recovery Act Research Support: Administrative supplement to fund undergraduate students during the summer quarter, and a visiting scientist, to perform behavioral studies as a means of accelerating our research pace. | Health and Human Services, Department of / National Institutes of Health | 6/02/2009 |
| UNIVERSITY OF MARYLAND | $416,624 | Grant | Trans-NIH Recovery Act Research Support: Seven million people suffer bone fractures annually in the U.S. Musculoskeletal conditions cost $215 billion/year. These numbers are increasing dramatically as the population ages. This project will develop the first injectable, moderate load-bearing, mac | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF FLORIDA | $84,636 | Grant | Trans-NIH Recovery Act Research Support: P. gingivalis, a gram negative anaerobe identified as one of the putative oral bacteria associated with severe, chronic forms of periodontal disease, is a successful colonizer of oral tissues, and can invade and remain viable for extended periods in prima | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $16,300 | Grant | Trans-NIH Recovery Act Research Support: The objective of this application is to understand osteogenic mechanisms of stem cells from human exfoliated deciduous teeth (SHED) as a basis for the development of therapeutic technologies for repairing orofacial bone defects. Autologous grafts from lon | Health and Human Services, Department of / National Institutes of Health | 6/02/2009 |
| CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE/CWRU | $42,861 | Grant | Trans-NIH Recovery Act Research Support: Description (provided by applicant): Osteoporosis is a public health problem that affects approximately 25 million people in the United States. Regardless of the etiology, osteoporosis is characterized by an imbalance in bone remodeling, such that osteocl | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $99,675 | Grant | Trans-NIH Recovery Act Research Support: Periodontal disease initiation and progression occurs as a consequence of the host immune inflammatory response to oral pathogens. The purpose of this award is to 1)determine the role of over-expressed MKP-1 on IL-6 and TNFalpha mRNA in vitro, 2)determin | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $76,825 | Grant | Trans-NIH Recovery Act Research Support: Aberrant Ca2+ influx by SOCs mediate the pathological Ca2+ influx that is the nodal points in all forms of pancreatiitis. Aberrant Ca2+ influx triggers autophagy that targets digestive enzymes to the lysosomes and eventually kills the calls. We know tha | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| CHICAGO ASSOCIATION FOR RESEARCH AND EDUCATION IN SCIENCE | $85,608 | Grant | Trans-NIH Recovery Act Research Support: Despite substantial progress several fundamental issues of hypertensive renal damage remain unresolved. (1) The term 'BP load' is still used genetically due to the complexity of the BP phenotype because of its fundamental lability and oscillating phenotyp | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF NEVADA, RENO | $99,992 | Grant | Trans-NIH Recovery Act Research Support: In humans, abnormal colonic motor patterns have been implicated in the pathogenesis of severe transit constipation (STC) and diarrhea (Bueno et al., 1980). STC has been attributed to many factors including: an increase in NOS positive neurons within the | Health and Human Services, Department of / National Institutes of Health | 8/20/2009 |
| UMDNJ-ROBERT WOOD JOHNSON MEDICAL SCHOOL | $30,963 | Grant | Trans-NIH Recovery Act Research Support: Dr. Nicola C. Partridge received an Administrative Supplement for Parent Grant: 5R01KD047420-16: Nuclear Events in PTH Action on Bones Cells for three summer students. These extra funds for the summer students would significantly accelerate the tempo of | Health and Human Services, Department of / National Institutes of Health | 6/17/2009 |
| DUKE UNIVERSITY | $104,647 | Grant | Trans-NIH Recovery Act Research Support: Aim S1: One litter of Y17 H-chain-only Tg mice have been bred and initial phenotyping is in progress, using flow cytometry, cell culture, and ELISA assays. We anticipate preliminary data from this experiment will be available within the next two weeks. | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF NEW MEXICO | $89,928 | Grant | Trans-NIH Recovery Act Research Support: Autosomal Dominant Polycystic Kidney Disease (ADPKD) is caused by mutations in the genes encoding polycystin-1 and/or polycystin-2, but results in epithelial cells with disrupted adherensjunctions and compromised beta-catenin signaling pathways. Our data | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| WASHINGTON UNIVERSITY, THE | $92,927 | Grant | Trans-NIH Recovery Act Research Support: Short bowel syndrome resulting from diminished intestinal absorptive function is a major cause of morbidity and impaired quality of life. Although transplantation is an alternative for a small subset of selected patients, strategies designed to increase t | Health and Human Services, Department of / National Institutes of Health | 8/24/2009 |
| RHODE ISLAND HOSPITAL | $100,000 | Grant | Trans-NIH Recovery Act Research Support: Gastro-esophageal reflux disease (GERD) is by far the most common esophageal disorder, affecting more than one in ten adults over 40 years of age and one in four adults over 60. GERD may lead to the development of serious complications including ulcers, s | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| UNIVERSITY OF NEVADA, RENO | $96,900 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this administrative supplement is to complete original aims of a parent grant proposal that were cut due to administrative reductions. These aims which are essential to our understanding of gastric motor function will include the examinatio | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| SCOTT & WHITE MEMORIAL HOSPITL | $6,739 | Grant | Trans-NIH Recovery Act Research Support: This grant was to provide a summer research experience for one undergraduate student in health-related scientific research. During their research experience, the student will be exposed and trained in all aspects of the current research project including | Health and Human Services, Department of / National Institutes of Health | 6/22/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $30,240 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Little is known about the mechanisms or pathophysiology responsible for age-related decline of internal anal sphincter (IAS) function. Decreased mechanical efficiency of smooth muscle of the IAS results in decreased cl | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| THE WASHINGTON UNIVERSITY | $50,000 | Grant | Trans-NIH Recovery Act Research Support: The proliferative function of colonic epithelial progenitors during gut injury is maintained in part through the actions of prostaglandin E2 (PGE2) that is produced in the mesenchyme by Ptgs2. We found that high constitutive levels of Ptgs2 are produced b | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The pathogenesis of Crohn's disease involves chronic intestinal inflammation that waxes and wanes over time. After years of inflammation, patients develop intestinal fibrosis that can lead to strictures, fistulae and obstruction. Existing medications trea | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| MARQUETTE UNIVERSITY | $48,140 | Grant | Trans-NIH Recovery Act Research Support: This supplemental grant provided a summer research experience for three college undergraduates in health-related scientific research. The parent grant to this supplemental proposal examines the discrete anatomical, cellular, molecular and functional inte | Health and Human Services, Department of / National Institutes of Health | 6/18/2009 |
| DUKE UNIVERSITY | $101,400 | Grant | Trans-NIH Recovery Act Research Support: We have previously identified a point mutation in thes Transient Receptor Potential Cation Channel 6 (TRPC6) gene causing an autosomal dominant form of familial focal and segmental glomerulosclerosis (FSGS). This P112Q substitution causes a marked alterat | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $197,612 | Grant | Trans-NIH Recovery Act Research Support: We have demonstrated that the in a rat model. The overall hypothesis presented in this grant provides an integrated pathophysiological schema whereby the IGF-l/Akt/mTOR/p70S6 kinase signaling pathway can lead to apoptosis and proliferation, cyst formation | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON | $35,160 | Grant | Trans-NIH Recovery Act Research Support: Multiple sclerosis (MS) is a chronic central nervous system disease that affects 2.5 million patients worldwide. Currently, there is no cure for MS, but a number of disease modifying drugs have been either approved by the FDA or undergoing clinical trials | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| DUKE UNIVERSITY | $51,344 | Grant | Trans-NIH Recovery Act Research Support: The objective of the proposed research is to develop an ultrasonic, radiation-force based imaging system capable of locally quantifying the shear modulus of soft tissues throughout a 2D Field of View (FOV), and to investigate its utility in the context of | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF MARYLAND | $228,180 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of this research is to engineer peptide-based viscoelastic biomaterials (hydrogels) that can be used as encapsulated matrices for drug delivery and tissue repair applications. The focus of this proposal is on design principles, characte | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| UNIVERSITY OF FLORIDA | $44,732 | Grant | Trans-NIH Recovery Act Research Support: Dichloroacetate (DCA) is an environmentally important xenobiotic, widely distributed in our biosphere. It is also employed as an investigational drug for treating genetic mitochondrial (mt) diseases and cancer. ES07355 is focused on pin-pointing the mo | Health and Human Services, Department of / National Institutes of Health | 6/17/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $32,558 | Grant | Trans-NIH Recovery Act Research Support: The goal of the project is to understand the inherent characteristics of tissues and their interfaces involved in tooth attachment, such that they can be mimicked in long-term goal of functional tissue regeneration. | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| BOSTON COLLEGE, TRUSTEES OF | $782,500 | Grant | Trans-NIH Recovery Act Research Support: Glucose Energy Metabolism in the Growth and Survival of B Lymphocytes: Lymphocytes use considerable amounts of energy to maintain both housekeeping functions and to support growth and effector functions in response to antigen (Ag) challenge. Changes i | Health and Human Services, Department of / National Institutes of Health | 5/14/2009 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $257,768 | Grant | Trans-NIH Recovery Act Research Support: Our current research, supported by R01 DC008651, focuses on determining the pharmacokinetics, safety and efficacy of intratympanic antiviral drug delivery as a method for treating Cytomegalovirus (CMV)-related inner ear disease and hearing loss. The ratio | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $1,495,767 | Grant | Trans-NIH Recovery Act Research Support: This two-year study aims to explore the effects of prenatal and postnatal exposure to common insecticides (organophosphates and pyrethroids) by assessing neurobehavior during the newborn period and through age 4 years among an established 400-person cohor | Health and Human Services, Department of / National Institutes of Health | 9/19/2009 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $7,500 | Grant | Trans-NIH Recovery Act Research Support: The infrastructure or incorporating summer students into research labs is well established at Cincinnati Children's Hospital Medical Center (CCHMC). A centralized, ongoing program, the Summer Undergraduate Research Fellowship (SURF) program at CCHMC prov | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $736,530 | Grant | Trans-NIH Recovery Act Research Support: To enhance participant recruitment efforts for genetics studies and other large-scale etiological research efforts, there is a need for an instrument that can be practically and efficiently employed in research studies of autism spectrum disorders (ASD). | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $84,323 | Grant | Trans-NIH Recovery Act Research Support: The overall purpose of this supplement was to accelerate the tempo of the scientific research proposed in the parent grant by testing the hypothesis that p16 has Rb independent functions mediated through p107 that are critical in suppressing lung tumorige | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $365,238 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement will accelerate the tempo of scientific research, increase participant enrollment and capacity for data analyses, preserve the jobs of current staff, employ new staff and leverage NCI funds in our active grant: Molecular | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $49,195 | Grant | Trans-NIH Recovery Act Research Support: The project established magnetic resonance based physiologic biomarkers of malignant progression of glial tumors to improve noninvasive monitoring of patients with glioma | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $201,623 | Grant | Trans-NIH Recovery Act Research Support: R01 CA126792-01A2S1 (Autophagy and Epithelial Cell Fate during Anoikis and 3D Morphogenesis): This ARRA Competitive Revision tests the requirement for detachment-induced autophagy during cancer cell dissemination and metastasis using in vivo models of exp | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $800,838 | Grant | Trans-NIH Recovery Act Research Support: Project Title: A Technological Platform for the Identification of Serine Proteases in Cancer; Our goal in this project is to develop highly sensitive methods to monitor the activity of a class of enzymes known as proteases that have been implicated in ca | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| CARNEGIE MELLON UNIVERSITY | $592,971 | Grant | Trans-NIH Recovery Act Research Support: This award supports scientific research into cancer development and progression. The goal of the project is to develop computational methods for determining how cancerous cells within tumors accumulate genetic damage over time, causing them to become inc | Health and Human Services, Department of / National Institutes of Health | 5/11/2009 |
| NORTHEASTERN UNIVERSITY | $38,470 | Grant | Trans-NIH Recovery Act Research Support: Cannabinergic ligands and drugs | Health and Human Services, Department of / National Institutes of Health | 6/19/2009 |
| CARNEGIE MELLON UNIVERSITY | $88,700 | Grant | Trans-NIH Recovery Act Research Support: This supplement requested funds to purchase optical components including a scan head and fiber coupler for an existing microscope to allow rapid, multisite computer-controlled delivery of 355 nm ultraviolet laser light for photolysis of caged glutamate. T | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $59,182 | Grant | Trans-NIH Recovery Act Research Support: This is a study of the mutational analysis of E. Coli core RNA polymerase. | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $185,000 | Grant | Trans-NIH Recovery Act Research Support: The goal of this research is to improve cancer treatment using ligand-targeted liposome encapsulated drugs. Liposomes are microscopic, spherical structures prepared from phospholipids. Cancer drugs can be encapsulated inside the liposome. In this research | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $402,634 | Grant | Trans-NIH Recovery Act Research Support: This is significant to public health because it will determine if products of oxidative stress are biologically relevant biomarkers of diesel exhaust exposure-induced oxidative stress and asthma severity in children. Conequently, these and planned future | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| NORTHEASTERN UNIVERSITY | $390,000 | Grant | Trans-NIH Recovery Act Research Support: Activation-Inducible HIF1 Alpha in regulation of TCells during Bacterial Sepsis | Health and Human Services, Department of / National Institutes of Health | 5/05/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $424,875 | Grant | Trans-NIH Recovery Act Research Support: Imaging Nuclear Receptor LRH-1 in Functional Transcriptional Assemblies; Nuclear receptors regulate cell differentiation, metabolism, and can promote cancers. We identify assemblies of nuclear receptor LRH-1 with its regulators. Our goal is to determine s | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $42,500 | Grant | Trans-NIH Recovery Act Research Support: purchase a Real-Time q-PRC instrument to validate ATR targets and the knock-down of si-RNA | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| ARIZONA STATE UNIVERSITY | $91,470 | Grant | Trans-NIH Recovery Act Research Support: The aims of the supplement is to continue enhancement of the proposed research plan laid down in the parent grant. Specifically, we will focus on improving and expediting two specific aims of the parent proposal +?G??G? Specific Aims 1 and 3. | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| BLUE BELT TECHNOLOGIES, INC. | $148,302 | Grant | Trans-NIH Recovery Act Research Support: Skull base surgery is technically the most demanding of all of the neurosurgical procedures because of the intertwining of the hard, thick skull and delicate neural and vascular structures. A safer quicker and more precise way to remove the bony skull bas | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| VAN ANDEL RESEARCH INSTITUTE | $1,093,494 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (04) Clinical Research and the specific Challenge Topic, 04-CA-111: Quality of Cancer Surgery and Outcomes. This application also has specific relevance to broad challenge area (05) Comparative Effectiveness | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $944,072 | Grant | Trans-NIH Recovery Act Research Support: To examine and compare the feasibility, acceptability, and impact of conducting SBIRT through (1) a self-administered, web-based Personal Health Record compared to (2) a provider-administered protocol during clinic appointments. | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| NORTHEASTERN UNIVERSITY | $933,971 | Grant | Trans-NIH Recovery Act Research Support: Cultivation and domestication of previously uncultivated species from human oral | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $989,235 | Grant | Trans-NIH Recovery Act Research Support: Grant name: 'CFTR Inhibitors for therapy of polycistic kidney disease'. The goal of this grant is to select the best candidate molecule(s) for therapy of autosomal dominant polycystic kidney disease (AKPKD) to move forward in pre-clinical development. In | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $998,170 | Grant | Trans-NIH Recovery Act Research Support: The 'Adherence, Improvement & Measurement (AIM) System' grant works to develop an application to promote medication adherence using wireless technology, specifically examining adherence for antiretroviral medications and common medical and health conditio | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $1,812,291 | Grant | Trans-NIH Recovery Act Research Support: ZAP-70, a cytoplasmic enzyme involved in intracellular signaling, plays a critical role in T cells, as is underscored by the immunodeficiencies that result from zap70 gene inactivation. Thus, ZAP-70 is an attractive therapeutic target in T cell mediated a | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| NATIONAL DEVELOPMENT AND RESEARCH INSTITUTES, INC. | $3,439,782 | Grant | Trans-NIH Recovery Act Research Support: The majority of individuals in criminal justice settings across the U.S. have a critical need for sciencebased, psychosocial treatment that targets substance use and HIV risk behavior. The investigative team has developed and demonstrated the efficacy of | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF ILLINOIS | $302,990 | Grant | Trans-NIH Recovery Act Research Support: Kruppel-type zinc finger (ZNF) loci comprise one of the largest human gene families. In mammals, the majority of ZNF genes are of a single subtype, encoding proteins in which DMA-binding zinc finger arrays are attached to a chromatin-interacting domain, c | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF ILLINOIS | $528,476 | Grant | Trans-NIH Recovery Act Research Support: Spermatogonial stem cells from testes of adult mice and germline stem cells from testes of neonatal mice can generate pluripotent cells with developmental potential similar to embryonic stem (ES) cells. These results suggest that germ cells from the teste | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $600,000 | Grant | Trans-NIH Recovery Act Research Support: We submit this Administrative Supplement focusing on Research Workforce Development and Dissemination. The goal is to provide new training opportunities to the next generation of clinical and translational scientists, and disseminate the scientific proce | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| UNIVERSITY OF MISSOURI SYSTEM | $383,385 | Grant | Trans-NIH Recovery Act Research Support: The advent of artificial tissues, cord blood therapies, cell transplantation procedures, and the desire to bank germ cells have driven the need to establish a means to reliably store biological materials. Cryopreservation is an effective means to store bi | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $998,214 | Grant | Trans-NIH Recovery Act Research Support: This application addresses the development of technologies for assessment of aortic aneurysms prone to rupture or dissection In the current proposal we address a clinically relevant and pressing need to elucidate the mechanisms that (i) would enable us to | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $999,158 | Grant | Trans-NIH Recovery Act Research Support: The calcification of the Aortic Valve represents a multifactor process underling varied associated pathologies. Due to the high prevalence and mortality associated with aortic valve calcification novel biomarkers are constantly needed for an early diagnos | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF FLORIDA | $1,000,000 | Grant | Trans-NIH Recovery Act Research Support: Aim 1. Two inflammatory vascultis syndrome (IVS) mouse models are established. We have detected arterial inflammation and organ involvement with ?¡Ñ68HV infection in interferon gamma receptor KO (IFN?¡ÑR-/-) mice and in human ar | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $968,763 | Grant | Trans-NIH Recovery Act Research Support: Develop transgenic animal models that are informative for understanding chronic inflammation in humans. Macrophages play a key role in the pathogenesis of multiple chronic inflammatory diseases. Studies using knockout mice have allowed investigators to ex | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF CONNECTICUT | $500,000 | Grant | Trans-NIH Recovery Act Research Support: This project addresses the fundamental mechanism of Bernard-Soulier syndrome (BSS), a bleeding disorder due to problems in several molecules on platelets and their progenitors. Proteins must adopt a proper 3-dimensional shape in order to function. Such a | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| NEW YORK UNIVERSITY (INC) | $997,106 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge area (04) Clinical research, and specific Challenge Topic 04-HL-103 Assess the role of leukocyte interaction with platelets, erythrocytes, and endothelium in the pathogenesis of heart, lung, and blood diseases. C | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| THE VANDERBILT UNIVERSITY | $869,005 | Grant | Trans-NIH Recovery Act Research Support: Sepsis is characterized by systemic inflammation secondary to infection. It is common and can affect individuals of any age, race, or sex. More than 750,000 cases are diagnosed in the United States annually, and among patients with associated organ dysfun | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| CHILDREN'S HOSPITAL CORPORATION, THE | $999,984 | Grant | Trans-NIH Recovery Act Research Support: We propose to evaluate this functionality in formative study of 500 patients (children, a high priority population for NIH research) subject to genome-wide variant assays in our Developmental Medicine Center. The advent of genome-scale measurements and he | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $999,990 | Grant | Trans-NIH Recovery Act Research Support: This application addresses Broad Challenge Area (09): Health Disparities and the Specific Challenge Topic, 09 MD 103: Initiating Innovative Interventions to Prevent Family Violence. We are engaged in the large scale demonstration project evaluating the | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $955,834 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area 03: Biomarker Discovery and Validation and specific Challenge Topic, 03-MH-101 'Biomarkers in mental disorders.' The proposal is designed to develop a biomarker and physiological endophenotype for schizoaffe | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| THE UNIVERSITY OF SOUTH DAKOTA | $83,239 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement is designed to expand participant recruitment at the Rapid City one of the study locations in the Northern Plains Comprehensive Clinical Site of the Safe Passage Study. The Prenatal Alcohol in SIDS and Stillbirth (PASS) Net | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| MAYO CLINIC | $846,745 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (04) Clinical Research, and specific challenge Topic 04-HL-101: Identify Mechanisms Linking Cardiopulmonary Disease Risk and Sleep Disordered Breathing. Atrial fibrillation (AF), the most common sustained ar | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $1,000,000 | Grant | Trans-NIH Recovery Act Research Support: Our project is entitled 'Comparison of Novel Technologies to Improve Early Identification of Preclinical Coronary Atherosclerosis in High Risk Families.' Its prime purpose is to compare an innovative coronary artery imaging technology with a standard imag | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| BETH ISRAEL DEACONESS MEDICAL CENTER INC | $1,000,000 | Grant | Trans-NIH Recovery Act Research Support: This study deals with validating clinically relevant, quantifiable biomarkers of diagnostic and therapeutic responses for blood, vascular, cardiac, and respiratory tract dysfunction. This study will take the following approach, it establishes the hemodyna | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $1,000,000 | Grant | Trans-NIH Recovery Act Research Support: We propose to perform DNA resequencing collected cohorts with extreme lipid phenoptypes (elevated LDL-C, triglycerides and HDL-C). We will resequence areas of the genome that have been identified as potential loci affecting lipid traits in genome wide ass | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $1,000,000 | Grant | Trans-NIH Recovery Act Research Support: This application addresses Broad Challenge Area (08): Genomics and specific Challenge Topic, 08-HL-104: Assess Genetic Variation in African Americans and determine its effect on disease. Coronary artery disease (CAD) is a leading cause of death worldwide | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF FLORIDA | $981,996 | Grant | Trans-NIH Recovery Act Research Support: Angiotensin converting enzyme 2 (ACE2) is the key enzyme of the renin-angiotensin system present in endothelial cells. ACE2 produces angiotensin-(1-7) [Ang-(1-7)] which prevents the vasoconstrictive, proliferative, fibrotic and inflammatory effects of Ang | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| THE JACKSON LABORATORY | $998,844 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (15) Translational Science, and specific Challenge Topic, 15- CA-104: Use of novel mouse genetic resources to elucidate determinants of drug toxicities. Variation in the efficacy and toxicity of chemotherape | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF MARYLAND | $773,678 | Grant | Trans-NIH Recovery Act Research Support: This NIH Challenge Grant application addresses the specific Challenge Area (05): Comparative Effectiveness Research, and the specific Challenge Topic, 05-CA-104: Comparative Effectiveness Research in Cancer Treatment. This study will examine patterns of t | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| BRIGHTOUTCOME INC. | $999,413 | Grant | Trans-NIH Recovery Act Research Support: There is a growing recognition of the importance of subjective patient-reported outcomes (PRO) in patient care. Several recent studies have observed positive impacts of routine use of PRO assessments in clinical practice, reporting improved physical, fun | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF TEXAS M D ANDERSON | $1,000,000 | Grant | Trans-NIH Recovery Act Research Support: In response to: 14-CA-102 Understanding the Heterogeneity of Cancer and its Environment. Assembly and disassembly of stromal architecture in the tumor microenvironment. Frank Marini- UTM.D. Anderson Cancer Center To meet the requirements for rapid tumor g | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| SMITHSONIAN INSTITUTION | $990,443 | Grant | Trans-NIH Recovery Act Research Support: We have developed a prototype x-ray microanalysis system with unprecedented spatial and spectroscopic resolution. It combines two state-of-the-art instruments. One is a cryogenic x-ray microcalorimeter that we built several years ago for x-ray astronomy m | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $999,914 | Grant | Trans-NIH Recovery Act Research Support: This application addresses the broad Challenge Area (15) Translational Science, 15-CA-103: Thyroid Cancer Cell Line Project which is in direct response to our recent discovery showing that 17 out of 40 'thyroid' cancer cell lines are either redundant or m | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $993,343 | Grant | Trans-NIH Recovery Act Research Support: Peptide-mediated immunotherapy of KSHV-associated malignancy Research Area: 5-DE-109 Novel Immunotherapies to Treat HIV/AIDS-related Oral Manifestations and AIDS Malignancies Kaposi sarcoma (KS), specifically oral KS, is the leading cause of cancer in pat | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $961,655 | Grant | Trans-NIH Recovery Act Research Support: Maximizing Effectiveness of Integrated Treatment Approaches. The present study uses behavioral reinforcement to motivate opioid dependent patients with any co-occurring psychiatric disorder to attend scheduled psychiatric appointments and mental health co | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| OREGON SOCIAL LEARNING CENTER | $998,445 | Grant | Trans-NIH Recovery Act Research Support: The awarded project, Womens Substance Use and Intimate Partner Violence, explores the nature of the relationship between family violence and substance abuse. The proposed research will improve our understanding of (a) the contribution of substance use an | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| RFCUNY - JOHN JAY COLLEGE OF CRIMINAL JUSTICE | $736,858 | Grant | Trans-NIH Recovery Act Research Support: This project will create an agent-based simulation of Injection Drug Using networks to better understand how HIV does and does not spread over time. At the heart of this project is the well documented but as yet not understood phenomenon of sub-saturation | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| NATIONAL JEWISH HEALTH | $253,636 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement is critical to accelerate the tempo of scientific research activities in Aim 3 of our parent RO1 grant (RO1 HL088264). As a result, a new job position will be created. G?? We will complete the generation of SPLUNC1 knockou | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| RHODE ISLAND HOSPITAL | $200,000 | Grant | Trans-NIH Recovery Act Research Support: The aim of this project is to determine the receptor signaling pathways by which the natriuretic peptides (NP) modulate pulmonary microvascular endothelial cell (PMVEC) barrier function and pulmonary edema formation. Pulmonary edema is the primary cause o | Health and Human Services, Department of / National Institutes of Health | 8/12/2009 |
| CHILDREN'S HOSPITAL CORPORATION, THE | $200,727 | Grant | Trans-NIH Recovery Act Research Support: Safe Pediatric Trial of Euglycemia in Cardiac Surgery (SPECS) Critically ill neonates and children commonly develop stress hyperglycemia which is significantly associated with increased morbidity and mortality. In critically ill adults several clinical tr | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $256,406 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The long-term objectives of this proposal are to develop compliant, thoracic artificial lungs (cTALs) that can be used as a bridge to transplant for patients with end-stage respiratory disease. As a bridge to lung tran | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| THE VANDERBILT UNIVERSITY | $250,037 | Grant | Trans-NIH Recovery Act Research Support: A recent study has shown that apoE and one of its receptors, LDLr, are involved in the uptake of glycolipid antigen and subsequent activation of NKT cells. This led us to postulate that other receptors important for lipid uptake would be involved in anti | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE/CWRU | $234,751 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Beta-adrenergic receptor (bAR) signaling is one of the most powerful regulators of cardiac function. In human heart failure, diminished receptor numbers at the plasma membrane associated with impaired G-protein couplin | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $189,438 | Grant | Trans-NIH Recovery Act Research Support: The family of heterodimeric integrin cell adhesion receptors regulates cell migration, survival, and differentiation in metazoa by responding to intra- and extracellular signals in inside-out and outside-in signaling pathways, respectively. Integrin alpha | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| CEDARS-SINAI MEDICAL CENTER | $279,898 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Coronary artery disease (CAD) continues to be a major public health problem. It is the single greatest cause of death for men and women in the US, accounting for 20% of all deaths. While there are effective medical and | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF ROCHESTER | $238,014 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement to the parent R01 aims to accelerate our project investigating the functional role of Mena (the mammalian homologue of drosophila enabled) in the heart. | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $39,294 | Grant | Trans-NIH Recovery Act Research Support: The project aims to provide summer research training for undergraduate students. Bioinformatics is a new interdisciplinary science that plays critical role in future high throughput biomedical research. Through providing hands on research experience, th | Health and Human Services, Department of / National Institutes of Health | 6/02/2009 |
| TEXAS ENGINEERING EXPERIMENT STATION | $36,625 | Grant | Trans-NIH Recovery Act Research Support: PROJECT SUMMARY When the vocal fold (VF) lamina propria (LP) composition, geometry, and viscoelasticity are altered due to scarring, VF vibratory function can be severely disrupted, with resultant dysphonias ranging from hoarseness to voice loss. VF scarr | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $18,905 | Grant | Trans-NIH Recovery Act Research Support: This R03 application is for one year of funding to develop and release SPHARM-MAT, a 3D shape modeling and analysis toolkit for neuroanatomical studies. Shape analysis is becoming of increasing interest to the neuroimaging community because of its potenti | Health and Human Services, Department of / National Institutes of Health | 6/16/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $39,865 | Grant | Trans-NIH Recovery Act Research Support: ARRA Supplement to Environmental Exposure to Metal Mixtures and Kidney Disease PROJECT SUMMARY Humans are exposed to chemical mixtures in all environmental media, yet environmental policies rest primarily on studies of single chemical exposures. Secondary | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| UNIVERSITY OF WASHINGTON | $74,252 | Grant | Trans-NIH Recovery Act Research Support: Vertical HIV-1 transmission rates continue to be high in resource limited settings, even when antiretroviral regimens are fully implemented. Current approaches to reducing vertical HIV-1 transmission during breastfeeding are primarily focused on modifyin | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| CLARKSON UNIVERSITY | $75,000 | Grant | Trans-NIH Recovery Act Research Support: The objective of this supplement is to examine the potential synergy between Erlotinib and NF-kB inhibitors in inducing apoptosis of HPV-expressing cervical cells. This work will expand on specific aim 2-1C of the parent grant. Flow cytometry will be used | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| UNIVERSITY OF TEXAS AT ARLINGTON | $80,730 | Grant | Trans-NIH Recovery Act Research Support: The goal of this AREA research project is to investigate the effects of various chemical gradients on prostate cancer cell migration and the involved mechanisms using an enabling microfluidic platform in order to elucidate the mechanisms of prostate cance | Health and Human Services, Department of / National Institutes of Health | 6/02/2009 |
| OAKLAND UNIVERSITY | $15,700 | Grant | Trans-NIH Recovery Act Research Support: In this study zebrafish will be established as a model organism to study arsenic metabolism and toxicity. In order to understand the toxicity of arsenic metalloids, it is necessary to identify how they are taken up into cells. Therefore we will initiate s | Health and Human Services, Department of / National Institutes of Health | 7/11/2009 |
| PRESIDENT & TRUSTEES OF WILLIAMS COLLEGE | $79,200 | Grant | Trans-NIH Recovery Act Research Support: The project goals are to improve the utility of bioinformatics tools and compute how RNA binding is modulated in splicing and other contexts. Bill contributed to three projects: (1) an improvement to our BINDIGO algorithm's functionality in which we can | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| FORDHAM UNIVERSITY | $132,375 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): As complete genome sequences of intracellular bacterial symbionts and pathogens accumulate, an emerging trend is that transposable insertion sequence (IS) elements often proliferate after bacteria transition from a fre | Health and Human Services, Department of / National Institutes of Health | 8/12/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $1,000,000 | Grant | Trans-NIH Recovery Act Research Support: Persistent high risk human papillomavirus (HPV) infection is a significant cause of anogenital cancers in HIV- positive individuals. The long-term goal of this study is to understand how HPV interacts with one of the same host receptors as HIV and to find | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| ROCKEFELLER UNIVERSITY FACULTY AND STUDENTS CLUB INC, THE | $2,595,872 | Grant | Trans-NIH Recovery Act Research Support: The broad focus of this research program is the epigenetic regulation of transcription and how this relates to cancer, and our program is rooted in the idea that an indexing system exists for our genome, or what has been referred to as a 'histone or epige | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| WAKE FOREST UNIVERSITY | $2,750,631 | Grant | Trans-NIH Recovery Act Research Support: Illicit drug use is not only a major global health problem, but has also had a profoundly negative social, political, and economic impact that continues to increase in magnitude. Although treatments such as the nicotine patch or methadone have been useful | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| INTERVEXION THERAPEUTICS, LLC. | $3,964,137 | Grant | Trans-NIH Recovery Act Research Support: Title: Chimeric anti-Methamphetamine Monoclonal Antibody for Treating Stimulant Toxicity Description: We have developed a new medication for treating toxic effects from overdose and long-term use of (+)-methamphetamine, (+)-amphetamine, and (-?)methylene | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| OREGON RESEARCH INSTITUTE | $3,402,213 | Grant | Trans-NIH Recovery Act Research Support: The National Institute on Drug Abuse has funded the Promise Neighborhood Research Consortium (PNRC) to assist the people from high-poverty neighborhoods in America to learn about and understand existing knowledge about prevention and to work together | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $4,000,000 | Grant | Trans-NIH Recovery Act Research Support: The primary goal of this proposal is to increase the pace of experimental determination of the function of large and high priority gene families in bacterial genomes. These genes can help elucidate the mechanisms of antibiotic resistance, provide new drug | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $2,000,000 | Grant | Trans-NIH Recovery Act Research Support: Because of the diversity of niches they inhabit, their versatility, and the threat their members pose to human health, Gram-positive bacteria are of paramount importance to multiple facets of microbiology. Nonetheless, there has been no systematic effort | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $2,453,703 | Grant | Trans-NIH Recovery Act Research Support: Development of Electron Microscopy-based Nucleic Acid Polymer Sequencing - We aim to provide a comprehensive foundation for development of an ultra-low-cost, ultra-fast nucleic acid polymer sequencing technology based on single-atom resolution transmissio | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $131,716 | Grant | Trans-NIH Recovery Act Research Support: Systemic Lupus Erythematosus (SLE) is a multi-organ autoimmune disease with rising mortality that targets primarily young women and children of U.S. minorities. Although childhood-onset SLE (cSLE) has similar disease features as SLE in adults, children of | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $233,375 | Grant | Trans-NIH Recovery Act Research Support: The Mixed Lineage Leukemia (Mll) gene encodes a chromatin modifying protein that can be deregulated by many different chromosomal translocations to result in leukemia. We have shown that the murine Mll gene is essential for the development of hematopoieti | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| UNIVERSITY OF WASHINGTON | $314,594 | Grant | Trans-NIH Recovery Act Research Support: As life expectancy of HIV-positive (HIV+) patients has increased for those receiving highly active antiretroviral therapy (HAART), chronic complications from smoking contribute substantially to morbidity and mortality. We have demonstrated that chronic ob | Health and Human Services, Department of / National Institutes of Health | 8/27/2009 |
| MEDICAL COLLEGE OF WISCONSIN, INC., THE | $266,742 | Grant | Trans-NIH Recovery Act Research Support: Over the past four decades, endothelial cells lining the vessel wall have become an intense subject of clinical interest because blood vessels allow relatively easy access for drug delivery. Angiogenesis, or growth of new blood vessels is widely associate | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $332,781 | Grant | Trans-NIH Recovery Act Research Support: Over-anticoagulation is a strong modifiable risk factor for hemorrhage among warfarin users. To avoid the higher risk of hemorrhage, the American College of Chest Physicians has established guidelines including omission of warfarin doses and administering | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $266,062 | Grant | Trans-NIH Recovery Act Research Support: Our long-term objectives are to advance the understanding of the molecular mechanism(s) that govern the self-renewal property of leukemic stem cells (LSCs). LSCs are cells that can give rise to leukemia in transplant models, and therefore have self-renewa | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| UNIVERSITY OF ILLINOIS | $324,006 | Grant | Trans-NIH Recovery Act Research Support: This supplement is targeted to expand the assessment of immunological and nutritional profile of patients enrolled in our prospective randomized clinical trial to evaluate the impact of the intensive medical nutritional therapy (IMNT) intervention on immu | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF MARYLAND | $140,994 | Grant | Trans-NIH Recovery Act Research Support: This project, Computational Gene Modeling and Genome Sequence Assembly, addresses two major bioinformatics problems: the development of better software for finding genes in eukaryotic genomes, and the development of genome assemblers for large shotgun seq | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| NEW JERSEY INSTITUTE OF TECHNOLOGY | $238,300 | Grant | Trans-NIH Recovery Act Research Support: Award title: Partitioning to Support Auditing and Extending the UMLS/Admin Supplement. The proposed research supports our original grant concerning auditing of the UMLS. We design techniques for finding inconsistencies in the widely used UMLS and buil | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| UNIVERSITY OF WASHINGTON | $207,595 | Grant | Trans-NIH Recovery Act Research Support: Few information tools exist to support patients in their new active role in managing their own health care in this increasingly specialized and fragmented health care arena. In particular, patients often must coordinate their health care across multiple c | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| NORTHERN CALIFORNIA INSTITUTE FOR RESEARCH AND EDUCATION, INC. | $193,463 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this study is to enhance risk prediction through secondary data collection and analysis in an ongoing randomized clinical trial (RCT) of neuroplasticity-based cognitive training for young people at ultra-high-risk psychosis. Although the pr | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| MICHIGAN STATE UNIVERSITY | $267,733 | Grant | Trans-NIH Recovery Act Research Support: The overarching aim of this supplement is to quicken the pace of scientific discovery in the parent grant by updating technologies used for data collection. We will develop an on-line data collection system that will build information technology infrastru | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF SOUTH FLORIDA | $259,674 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): This revised competing continuation proposal is a request for funding to explore the patterns of immune, endocrine, and inflammatory changes over the postpartum period and to analyze potential relationships between the | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $165,157 | Grant | Trans-NIH Recovery Act Research Support: This is a proposal for an Administrative Supplement for parent grant NS012601-34 entitled Signal Transduction at Neuronal Nicotinic Synapses?. It examines the interactions of nicotinic and GABAergic signaling pathways, the effects of nicotinic input on s | Health and Human Services, Department of / National Institutes of Health | 8/07/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $708,808 | Grant | Trans-NIH Recovery Act Research Support: The basis of the competitive revision was our previously obtained evidence that neurogenic stem cells in the adult bowel contribute to the enteric nervous system (ENS). 5-HT4 agonists and mucosal inflmmation mobilize these stem cells to give rise to new | Health and Human Services, Department of / National Institutes of Health | 9/20/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $95,250 | Grant | Trans-NIH Recovery Act Research Support: Our recent work on this grant has demonstrated that PDE4 and other cyclic AMP pathways have an important role in brain microvascular endothelial fibrinolysis, which is negatively regulated by the blood-brain barrier(BBB). Earlier work on this grant has sh | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| TRUSTEES OF TUFTS COLLEGE INC | $22,096 | Grant | Trans-NIH Recovery Act Research Support: This award is providing a summer research experience for an undergraduate student with an interest in pursuing a career in neuroscience and accelerating the tempo of work on the parent grant. The aim of the parent grant is to gain insights into molecul | Health and Human Services, Department of / National Institutes of Health | 7/19/2009 |
| UNIVERSITY OF MARYLAND | $38,523 | Grant | Trans-NIH Recovery Act Research Support: The goal of this project is to investigate the principles through which different sensory modalities are combined to help balance control during standing. We propose to expand our focus to the more challenging movement behavior of locomotion to investigat | Health and Human Services, Department of / National Institutes of Health | 7/29/2009 |
| H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | $283,680 | Grant | Trans-NIH Recovery Act Research Support: Colorectal cancer is one of the leading cancers in Puerto Rican, second only to prostate and breast cancer. Inflammatory bowel diseases such as ulcerative colitis and Crohn's disease have been linked to the development of colorectal cancer. Evidence obtai | Health and Human Services, Department of / National Institutes of Health | 9/27/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $993,710 | Grant | Trans-NIH Recovery Act Research Support: Advanced MRI acquisitions have tremendous potential to investigate tissue structure and functions, but require substantial image processing resources. The creation of an image processing Core at OHSUG??s Advanced Imaging Research Center will significantl | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $1,591,661 | Grant | Trans-NIH Recovery Act Research Support: We propose to unite new technologies and new informatics/statistics methods to the broad benefit of the field of translational research. The overall purpose of the three linked supplemental requests is to develop, implement, and demonstrate the feasibilit | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| WASHINGTON UNIVERSITY, THE | $546,039 | Grant | Trans-NIH Recovery Act Research Support: A Workforce Development Administrative Supplement was requested to enhance the existing clinical and translational research training programs at the Washington University (WU) Clinical Research Training Center (CRTC). The goal of the CRTC is to provide ou | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY | $392,929 | Grant | Trans-NIH Recovery Act Research Support: Stroke is a disease of aging and a leading cause of adult disability in the U.S. In spite of the paucity of treatment strategies in a setting of acute ischemia, increasing evidence suggests that synaptic plasticity and remodeling occur weeks after stroke. | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY | $574,232 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement to the WCMC Clinical and Translational Science Center (CTSC) is an extension of the education arm of the its community outreach program to provide wide scale health education and awareness through long distance learning to u | Health and Human Services, Department of / National Institutes of Health | 9/26/2009 |
| UNIVERSITY OF CHICAGO, THE | $1,924,346 | Grant | Trans-NIH Recovery Act Research Support: The ultimate goals of the University of Chicago CTSA program are to train scientists and health care providers at the University, our partner institutions, and our community to determine the molecular underpinnings of disease or disease predisposition in | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $529,497 | Grant | Trans-NIH Recovery Act Research Support: Significant health disparities exist among population subgroups. Attempts to narrow these gaps require full engagement of the populations at risk. To ensure adequate recruitment and retention of study participations that reflect the population(s) at risk, | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $595,096 | Grant | Trans-NIH Recovery Act Research Support: In our parent grant, we identified a number of key barriers for clinical and translational research: lack of expert guidance and mentorship in multidisciplinary research; lack of coordinated and easy access to resources or infrastructure; insufficient pro | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $1,991,600 | Grant | Trans-NIH Recovery Act Research Support: Circulating endothelial cells (CECs) have been shown to be readily detectable in patients with acute coronary syndromes and appear to be remarkably predictive of an impending arterial catastrophe (heart attack or stroke). Even though these cells were disc | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| RELIGENT, INC. | $249,037 | Grant | Trans-NIH Recovery Act Research Support: Religent, along with the Duke University Medical Center, is developing a Web Service (SEBASTIAN) that will provide clinical decision support to routine clinical practices using a standards-based approach. A component of this is the Decision Engine (DE) wh | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| COMMUNICATION DISORDERS TECHNOLOGY INC | $35,286 | Grant | Trans-NIH Recovery Act Research Support: This award was provided for the development of a telephone screening test for hearing impairment, similar to those currently in use in the Netherlands, the UK, Australia, Germany and France. Roughly 80% of the hearing impaired persons in the US have never | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| NESHER TECHNOLOGIES INC | $80,842 | Grant | Trans-NIH Recovery Act Research Support: The parent proposal of this Administrative Supplement award under the American Recovery and Reinvestment Act (ARRA) seeks to expand the user-base of single molecule spectroscopies by creating a simple, cost-effective, and ultra-stable commercial single mo | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| SHIFA BIOMEDICAL CORPORATION | $17,458 | Grant | Trans-NIH Recovery Act Research Support: Heart disease is the leading cause of death for both men and women in the US, accounting for nearly 40% of all annual deaths. A high cholesterol level is a well-known risk factor for heart disease. Although blood cholesterol can be lowered using a number | Health and Human Services, Department of / National Institutes of Health | 6/03/2009 |
| STRATATECH CORPORATION | $99,916 | Grant | Trans-NIH Recovery Act Research Support: Enhancing the Vascularization Properties of Skin tissue Production of clinical-grade cell banks for a human skin substitute engineered to enhance the vascularization and healing of chronic wounds | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| WRIGHT, GEORGE E | $39,858 | Grant | Trans-NIH Recovery Act Research Support: Scope of overall project and anticipated contribution of supplement. The overall project is to advance a hybrid antibiotic AU-FQ compound consisting of a Gram+ DNA polymerase III inhibitor and a fluoroquinolone, to IND status with the FDA. Experiments in | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| NANOPROBES INC | $295,393 | Grant | Trans-NIH Recovery Act Research Support: Cancer imaging is important for tumor detection, determination of prognosis qnd treatments, image guided surgery and irradiation, as well as for monitoring responses. Molecular imaging of scientific targets could identify tumor types and enable selection | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| VIEW PLUS TECHNOLOGIES INC | $75,914 | Grant | Trans-NIH Recovery Act Research Support: The long range goal of this project is to create technologies that permit authors and publishers of professional journals to make their content available in the DAISY (Digital Accessible Information System) XML (eXtensible Markup Language) format that is | Health and Human Services, Department of / National Institutes of Health | 6/03/2009 |
| FRED HUTCHINSON CANCER RESEARCH CENTER | $300,220 | Grant | Trans-NIH Recovery Act Research Support: In this project, we will hire a Community Health Educator (CHE) to respond to a community-identified need to update, expand, and adapt Cancer 101: A Cancer Education and Training Program for American Indians and Alaska Natives. Cancer 101 is an evidence | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| THE WASHINGTON UNIVERSITY | $496,022 | Grant | Trans-NIH Recovery Act Research Support: Breast cancer is a difficult disease to manage because it is comprised of a wide spectrum of tumor subtypes with different biological characteristics, therapeutic responses and clinical outcomes. A biomarker-based classification of breast cancer that effe | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $800,001 | Grant | Trans-NIH Recovery Act Research Support: Although utilization of engineered nanomaterials (ENM) due to expansion of the science and application of nanobiomedicine/technology is expected to markedly increase, the mechanisms by which ENM injure and/or are transported into/across lung alveolar epit | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| SAINT LOUIS UNIVERSITY | $217,150 | Grant | Trans-NIH Recovery Act Research Support: This research explores mechanisms of DNA recombination and repair and is important for understanding origins of multiple diseases including premature aging, cancer and developmental disorders. | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $183,210 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this award is to continue research funded by R01-GM073932, Catalytic Methods for Carbon-Carbon and Carbon-Heteroatom Bond Formation. This research has focused on the development of new transition metal-catalyzed reactions for the preparatio | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| THE VANDERBILT UNIVERSITY | $62,633 | Grant | Trans-NIH Recovery Act Research Support: My RO1 grant (1 R01 GM074044; G?Developmental Regulation of the Cell Cycle in DrosophilaG?) consists of three aims: How does the PNG kinase substrate, GNU, regulate early embryonic cell cycles? 2) What is the mechanism by which Mat89Bb/ASUN regulates the | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $141,696 | Grant | Trans-NIH Recovery Act Research Support: This is a supplemental award to the main NIH grant which seeks to understand how the Chd1 remodeler moves nucleosomes through biophysical and biochemical analyses. A major component of this study focuses on obtaining structural snapshots of Chd1 and Chd1- | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| CALIFORNIA INSTITUTE OF TECHNOLOGY | $212,733 | Grant | Trans-NIH Recovery Act Research Support: All organisms must sense and respond to mechanical force in their external environment for proper growth, development, and health. The three PIs on this grant share an interest in how proteins accomplish the task of force perception, and we investigate th | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| DUKE UNIVERSITY | $1,975,573 | Grant | Trans-NIH Recovery Act Research Support: Heavy habitual consumption of alcohol leads to progressive injury and fibrosis in several tissues, including the liver. However, many heavy drinkers do not develop advanced liver fibrosis (i.e., cirrhosis) despite years of alcohol abuse. More modest consu | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| ERNEST GALLO CLINIC AND RESEARCH CENTER | $2,020,854 | Grant | Trans-NIH Recovery Act Research Support: Characterizing Alpha5* Nicotinic Receptors in Alcohol and Nicotine Co-Dependence We have developed a multidisciplinary collaborative research program focused on defining the molecular basis of the role of neuronal nicotinic receptors (nAChRs) in ethanol | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $5,401,791 | Grant | Trans-NIH Recovery Act Research Support: Alzheimer's disease affects over 5 million people in the US costing the Federal Government over $100 billion dollars/year. Because our population is aging, in 2050, if the disease remains untreatable, there will be 16 million people in the US with AD cos | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $76,500 | Grant | Trans-NIH Recovery Act Research Support: The yeast Saccharomyces cerevisiae responds to a variety of stress conditions (e.g., zinc depletion) by regulating the expression of several enzyme activities including those involved in phospholipid synthesis. Zinc is an essential nutrient required for t | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $205,146 | Grant | Trans-NIH Recovery Act Research Support: The ability of cells, tissues, and organisms to sense and respond to changes in oxygen levels is often crucial to their survival. Cellular adaptation to hypoxia is a good example of this. Intermittent episodes of hypoxia are associated with a variety of h | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND | $70,043 | Grant | Trans-NIH Recovery Act Research Support: Obesity is the most pressing nutritional problem in the United States. Neighborhood environments may contribute to this problem by providing excess availability of calorie-dense snack foods and insufficient availability of low-calorie nutritious foods suc | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| UNIVERSITY OF HOUSTON SYSTEM | $181,800 | Grant | Trans-NIH Recovery Act Research Support: The goal of the parent program is to begin development of electromagnetic sensors to detect abnormalities in mitochondrial metabolism that lead to type 2 diabetes and cardiovascular disease in obese patients. The sensors measure the responses (impedance | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $153,275 | Grant | Trans-NIH Recovery Act Research Support: To accelerate the rate of progress on the parent grant (1R21DA025800: Applying peptide and protein domain microarrays to epigenetic research), we request funds to (1) retain a Research Assistant/Lab Manager who may otherwise be terminated (The technician | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| PHYLONIX PHARMACEUTICALS, INC. | $75,518 | Grant | Trans-NIH Recovery Act Research Support: NIH Notice NOT-OD-09-060. Administrative Supplement providing summer research experiences for students and science educators. Hire 2 summer students in 2009 and 2010 to speed up the tempo of research on an existing funded grant. Students provide general l | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| DUKE UNIVERSITY | $226,289 | Grant | Trans-NIH Recovery Act Research Support: With funding from a pilot project from the Harvard Center for Medical Countermeasures against Radiation, we have utilized sophisticated mouse genetics to determine the role of the intrinsic pathway of apoptosis in the acute radiation syndrome. Through the | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| WASHINGTON UNIVERSITY, THE | $229,243 | Grant | Trans-NIH Recovery Act Research Support: Cardiovascular diseases (CVD) affect millions of people in US and across the world. There is strong evidence of a genetic component in cardiovascular diseases (CVD) and related traits. An emerging consensus is that both genes and environment and, perhaps | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| ST LUKE'S-ROOSEVELT HOSPITAL CENTER | $278,981 | Grant | Trans-NIH Recovery Act Research Support: The overall purpose of this award supplement is to determine whether sleep duration affects: 1.hormones associated with food intake not previously included in the parent grant, such as cholecystokinin (CCK); 2.lipid profile, ie. total cholesterol (TC), lo | Health and Human Services, Department of / National Institutes of Health | 7/30/2009 |
| ARIZONA STATE UNIVERSITY | $100,000 | Grant | Trans-NIH Recovery Act Research Support: As a microarray based laboratory, we heavily depend on a microarray scanner to visualize our arrays for later data acquisition and analysis. Our Perkin Elmer microarray scanner has required repair every 3-4 months with each repair period ranging from 1 to | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH | $169,761 | Grant | Trans-NIH Recovery Act Research Support: This grant provides, underrepresented minority individuals who have received undergraduate degrees in science, a challenging, focused post-baccalaureate experience that will prepare them for acceptance into graduate and doctoral programs. | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| NORTHWESTERN UNIVERSITY | $126,517 | Grant | Trans-NIH Recovery Act Research Support: This Supplement would create a new full-time position for an expert in technical writing to achieve the following goals. This new position would rapidly accelerate achievement of our program objectives of maximizing the probability that supported students | Health and Human Services, Department of / National Institutes of Health | 8/07/2009 |
| UNIVERSITY OF PUERTO RICO-MEDICAL SCIENCES CAMPUS | $387,948 | Grant | Trans-NIH Recovery Act Research Support: Based on the successes and lessons learned, the University of Puerto Rico Mentoring Institute for HIV and Mental Health Related Research was created in 2008. The institute?s research-education mentoring program is based on a competency development model ( | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| TRANSLATIONAL GENOMICS RESEARCH INSTITITUE, THE | $239,974 | Grant | Trans-NIH Recovery Act Research Support: Coronary heart disease, arising mainly from dysregulated lipid metabolism, is the leading cause of death among individuals with type 2 diabetes mellitus. Although lipid levels are strongly dependent upon genetic factors, and numerous genetic variants unde | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| EASTERN VIRGINIA MEDICAL SCHOOL | $30,853 | Grant | Trans-NIH Recovery Act Research Support: We will use presteady state kinetic methods and electron microscopy to determine the mechanism of thin filament regulation of cardiac actomyosin ATP hydrolysis. Most biochemistry and physiology textbooks depict a steric blocking mechanism of thin filament | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $203,732 | Grant | Trans-NIH Recovery Act Research Support: Angiogenesis, the sprouting of new capillary blood vessels from existing vasculature, is a complex biological process of critical importance to the treatment of numerous pathologies and the success of tissue engineering. Amongst the many promising strateg | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $354,196 | Grant | Trans-NIH Recovery Act Research Support: We will use the adminstrative supplements to study the molecular mechanisms underlying the Pbx1controlled neural crest cell differentiation into vascular smooth muscle cells. Although not described in details in the parent proposal, this project is a dire | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| LA JOLLA BIOENGINEERING INSTITUTE | $382,064 | Grant | Trans-NIH Recovery Act Research Support: The goal of this supplement project is to add molecular modeling skills and capability at molecular dynamics (MD) and ab initio levels to the research methods of the parent grant. The central hypothesis is that the plasma membrane of endothelial cell a | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| HOWARD UNIVERSITY, INC. | $60,608 | Grant | Trans-NIH Recovery Act Research Support: Administrative supplement request for providing summer research experience under the parent grant PTSD and Nocturnal Blood Pressure. The supplement seeks to increase awareness of how exposure to violence and the response to stress increase morbidity in t | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| UNIVERSITY OF PITTSBURGH THE | $213,682 | Grant | Trans-NIH Recovery Act Research Support: Myocardial infarction (MI) is the leading cause of death in the world. The most common causes are blockages that restrict blood supply to the heart, leading to ischemic damage and necrosis. In response to MI, a repair mechanism ensues involving engulfment | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON | $244,686 | Grant | Trans-NIH Recovery Act Research Support: The ability of individual cells to communicate with each other is a fundamental property that allows them tocoexist in a context of multicellular organisms. Nitric oxide (NO) is one of the signaling molecules used tocommunicate with adjacent cells. A spec | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $164,827 | Grant | Trans-NIH Recovery Act Research Support: Medical decision support tools are increasingly available on the Internet and are being used by lay persons as well as health care professionals. The goal of some of these tools is to provide an individualized prediction of future health care related even | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $28,723 | Grant | Trans-NIH Recovery Act Research Support: To accelerate our research into scientific publication ethics while simultaneously stimulating the economy by means of job creation and retention. It will also allow us to provide enriching educational experiences to young adults who are just entering th | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $172,278 | Grant | Trans-NIH Recovery Act Research Support: The long-term objective of the parent proposal is to advance patient safety and reduce health care costs by developing automated methods that discover novel adverse drug events (ADE) based on information in clinical documents. The purpose of this competit | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH | $78,371 | Grant | Trans-NIH Recovery Act Research Support: The broad objective of the parent proposal is to identify and characterize the most critical molecular sites of interaction between drugs with antipsychotic activity, or potential anti-attention deficit hyperactivity disorder (ADHD) activity. The results | Health and Human Services, Department of / National Institutes of Health | 5/20/2009 |
| WASHINGTON UNIVERSITY, THE | $376,812 | Grant | Trans-NIH Recovery Act Research Support: This proposal explores the neural and psychological mechanisms of cognitive control. Control processes are thought to be the fundamentally important in enabling the flexibility, complexity, and sophistication of human cognition. Conversely, breakdowns in | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $25,836 | Grant | Trans-NIH Recovery Act Research Support: n/a | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| CLINICAL DIRECTORS NETWORK, INC. (CDN) | $29,286 | Grant | Trans-NIH Recovery Act Research Support: The long-term objective of this study (R01-MH074394 & R01-MH074399)is to reduce risk for HIV and other sexually transmitted diseases (STDs) during and after pregnancy among adolescents and young women (aged 14-21) receiving prenatal care in 14 Community H | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $300,696 | Grant | Trans-NIH Recovery Act Research Support: The requested supplement meets the Recovery Act goals. It created a full time job with benefits for the mentee. The research and career development experiences will accelerate the pace and achievement of scientific research by equipping her with the skil | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $14,644 | Grant | Trans-NIH Recovery Act Research Support: This grant is exploring the role of cell volume changes associated with the unique biology of malignant gliomas. The overarching hypothesis posits that well orchestrated cell volume changes accompany cell invasion, glioma cell proliferation and programmed | Health and Human Services, Department of / National Institutes of Health | 7/21/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $29,780 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): This proposal is a resubmission of our competing renewal application of our current project on the role of Na+-K+-Cl- cotransporter isoform1 (NKCC1) in cerebral ischemic damage. The long-term goal of the research is to | Health and Human Services, Department of / National Institutes of Health | 7/21/2009 |
| UNIVERSITY OF MASSACHUSETTS | $82,042 | Grant | Trans-NIH Recovery Act Research Support: The main goal of the supplemental ARRA funding is to find out the mRNA content of wild type huntingitn and mutant huntingtin (expanded CAG repeats) in human striatum and cortex. This is a critical question in potential therapy for Huntington's disease. | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| WAKE FOREST UNIVERSITY | $162,917 | Grant | Trans-NIH Recovery Act Research Support: Pain-related disorders cause an incalculable toll in human suffering and present a significant economic problem. The development of new treatments for these disorders is being hindered by a lack of information about the basic brain mechanisms that support | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $14,644 | Grant | Trans-NIH Recovery Act Research Support: 5R01NS040593-09; P.I. Lucas Pozzo-Miller, PhD; This grant is focused on the immediate actions of the neurotrophin BDNF on membrane currents and intracellular Ca2+ levels in hippocampal neurons. BDNF has recently emerged as a potent modulator of activity | Health and Human Services, Department of / National Institutes of Health | 7/21/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $351,093 | Grant | Trans-NIH Recovery Act Research Support: The objective of the parent RO1 application is to use high-field 17O-MR based CMRO2 imaging approach in combined with other established approaches including electrophysiology recording to study the neuro-metabolic relationship and the impact of the baseli | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $90,840 | Grant | Trans-NIH Recovery Act Research Support: This supplement requests funds to conjugate monoclonal antibodies with molecules capable of inhibiting channel current, thus imbuing the selectivity of anti-Kv2.1 and anti-Kv4.2 antibodies on formerly nonselective inhibitors. Two types of inhibitors will | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $336,785 | Grant | Trans-NIH Recovery Act Research Support: The following application is for supplementary funds to extend the studies of NS046789 on the role of ATP-dependent chromatin remodeling in neural development. ATP-dependent chromatin remodeling complexes are thought to regulate the mobility of nucleosome | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE | $115,500 | Grant | Trans-NIH Recovery Act Research Support: This award is issued in response to Notice OD-09-060, Recovery Act Administrative Supplements Providing Summer Research Experiences for Students and Science Educators. DESCRIPTION (provided by applicant): I am requesting a Recovery Act Competitive Revisio | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE | $98,412 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Recent studies have shown that striatal nitric oxide (NO)-producing interneurons play an important role in modulating striatal neural activity and motor behavior. NO is a gaseous neurotransmitter produced by NO synthas | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE | $199,692 | Grant | Trans-NIH Recovery Act Research Support: Facioscapulohumeral muscular dystrophy (FSHD) is a unique disorder involving shortening of an array of tandem 3.3-kb repeats. Unaffected individuals have 11-100 copies of this repeat, D4Z4, at both allelic subtelomeric regions on the long arm of chromosom | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO | $308,359 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement provides funding to significantly increase the currently funded part time salaries of two scientists whose circumstances have been negatively effected by the curent economic conditions. At the same time, increased efforts on | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| BETH ISRAEL DEACONESS MEDICAL CENTER INC | $80,744 | Grant | Trans-NIH Recovery Act Research Support: Stroke is the leading cause of disability in the United States of America. This is partly because patients have difficulty acquiring, or re-learning old skills. Enhanced skill acquisition could reduce the problem of re- learning old skills, and so reduce | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| PALO ALTO INSTITUTE FOR RESEARCH AND EDUCATION, INC. | $87,879 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this project is to establish a firm scientific basis for the validity of EMG decomposition and to promote its wider application in basic and clinical neurophysiology. This supplemental request seeks to advance this overall goal in two | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $183,578 | Grant | Trans-NIH Recovery Act Research Support: In this grant, we aim to understand the contribution of astrocytes to ischemic brain injury in the hippocampus. One of the most feared disabilities in survivors of cardiac arrest is neurological impairment. Global cerebral ischemia, as seen with adult car | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| WAYNE STATE UNIVERSITY (INC) | $752,460 | Grant | Trans-NIH Recovery Act Research Support: Our proposed competitive revision award will allow us to accelerate the tempo of our new scientific research and promote economic development in the U.S. A total of 4 new positions will be generated for job creation and retention as well as investment in | Health and Human Services, Department of / National Institutes of Health | 9/20/2009 |
| UNIVERSITY OF FLORIDA | $42,152 | Grant | Trans-NIH Recovery Act Research Support: The goal of this proposal is to enhance naturally occurring processes that can lead to partial improvement of phrenic motoneuron (PhMN) functions that were initially lost or modified after high cervical spinal cord injury (SCI) andto define underlying cha | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $224,557 | Grant | Trans-NIH Recovery Act Research Support: MR Measured Oxygen Metabolic Index in Ischemic Stroke - ARRA Supplement The proposed study aims to discern brain hypoxia and viable tissue under acute cerebral ischemic stroke conditions using a positron emission tomography (PET) with a hypoxia imaging ag | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| UNIVERSITY OF MIAMI | $22,314 | Grant | Trans-NIH Recovery Act Research Support: Cyclic Nucleotide Regulation in Traumatic Brain Injury: Traumatic brain injury (TBI) is a significant health concern, affecting 1.4 million people in the United States each year at a cost of $56 billion. Both focal and diffuse brain pathologies result f | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| GEORGIA HEALTH SCIENCES UNIVERSITY RESEARCH INSTITUTE, INC. | $224,522 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of our laboratory is to understand molecular mechanisms underlying the formation and maintenance of synapses. Our model is the NMJ, a cholinergic synapse between motoneurons and muscle cells. The NMJ exhibits the high degree of subcellu | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $34,708 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Reading the literature on any neurodegenerative condition quickly leads to a bewildering array of facts, some contradictory, regarding the correlations between known pathological and clinical features of the disease. T | Health and Human Services, Department of / National Institutes of Health | 7/26/2009 |
| THE JACKSON LABORATORY | $373,137 | Grant | Trans-NIH Recovery Act Research Support: The most common medical conditions, such as heart disease, cancer, autoimmune and brain disorders, are often genetically complex, influenced by the interaction of multiple genes with other factors such as diet and environment. This complexity makes it a c | Health and Human Services, Department of / National Institutes of Health | 9/20/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $27,521 | Grant | Trans-NIH Recovery Act Research Support: R01 NS064025; PI Linda Overstreet-Wadiche, PhD; Adult neurogenesis is a mechanism that links experiences with structural plasticity and regeneration of the adult brain. Despite the extensive literature supporting experience-dependent regulation of adult | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| CHILDREN'S HOSPITAL CORPORATION, THE | $181,084 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of our research is to continue to define the genetic bases of abnormal human cerebral cortical development. | Health and Human Services, Department of / National Institutes of Health | 8/21/2009 |
| UNIVERSITY OF MARYLAND | $37,680 | Grant | Trans-NIH Recovery Act Research Support: There are persistent questions regarding the evolution and function of the immune system. Previously studies performed in non-mammalian vertebrates have helped to reveal basic features of the immune system that are universal. In other cases, studies outsi | Health and Human Services, Department of / National Institutes of Health | 8/22/2009 |
| UNIVERSITY OF OKLAHOMA | $240,000 | Grant | Trans-NIH Recovery Act Research Support: This NIH supplement funds a post-doc to implement stable-isotope bird-tracking methodologies in conjunction with the parent grant efforts to better understand the role of wild birds in the spread of Highly Pathogenic Avian Influenza in Asia.Since late 200 | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| PACIFIC INSTITUTE FOR RESEARCH AND EVALUATION | $127,747 | Grant | Trans-NIH Recovery Act Research Support: Social norms intervention strategies are widely used on college campuses to reduce heavy drinking and alcohol-related harm. There is strong evidence that students misperceive (overestimate) the level of drinking that is normative among their peers, and it | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| HOUSE EAR INSTITUTE INC | $85,271 | Grant | Trans-NIH Recovery Act Research Support: This is an application for an administrative supplement in response to NOT-OD-09-056, title: Accelerating the Science, title code: ACC to the NIDCD. We aim to accelerate the parent project through: 1) recruiting a technical staff that conducts husbandry o | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| NETBIO, INC. | $4,818,047 | Grant | Trans-NIH Recovery Act Research Support: In order to protect civilian and military populations, it is critical to improve the diagnosis of NIAID Category A-C priority pathogens. More rapid, more sensitive, more specific, and more informative diagnosis than currently possible will allow earlier | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| ARIZONA STATE UNIVERSITY | $3,409,687 | Grant | Trans-NIH Recovery Act Research Support: The Administrative Unit will act to support and coordinate project administration and operation within the Center. A Physical Science Leader (Dr. Lindsay) and a Life Science Leader (Dr. Grady) and a project management team (a program manager and two coord | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF ILLINOIS | $282,602 | Grant | Trans-NIH Recovery Act Research Support: The overall objective of this U54 application is to characterize, at molecular and cellular levels, the hormonal pathways that regulate embryo implantation and fertility. Failure of the fertilized embryo to implant into the endometrium is a major cause o | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| CREIGHTON UNIVERSITY | $110,992 | Grant | Trans-NIH Recovery Act Research Support: Physiological and biomechanical analyses of Parkinsonian rigidity - ParkinsonG??s disease significantly impairs the quality of life of the individual. The disease currently affects at least 1.5 million Americans and an additional 75,000 cases are diagnos | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| CONNECTICUT COLLEGE | $21,472 | Grant | Trans-NIH Recovery Act Research Support: This AREA project investigates how contextual approaches to assessment can enhance our understanding of child psychopathology and our ability to interpret and predict children's responses to psychoeducational intervention. In contrast to widely used syndr | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| UNIVERSITY OF CHICAGO, THE | $151,279 | Grant | Trans-NIH Recovery Act Research Support: In an ongoing study of aging in free-ranging female rhesus monkeys, we have obtained evidence that chronic stress and repeated activation of the HPA axis in association with low social status and frequent reproduction result in heightened cortisol respons | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF OREGON | $64,708 | Grant | Trans-NIH Recovery Act Research Support: Grant Specific Aim 1: Our first specific aim is to characterize the neuro-cognitive and neuro-affective processes contributing to public good decisions via functional MRI (fMRI) in a manner that allows comparisons between the age ranges of 25-35 and 65-75 | Health and Human Services, Department of / National Institutes of Health | 6/22/2009 |
| SEQUELLA INC | $693,529 | Grant | Trans-NIH Recovery Act Research Support: Investigation of Synergy between Rifampin (RIF) and SQ109, a New Anti-TB Drug Candidate. Purpose is to replenish the SQ109 API so that we can complete the Specific Aims of the R21 grant, to have enough API to complete the investigation of SQ109 and RIF sy | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| WASHINGTON UNIVERSITY, THE | $160,702 | Grant | Trans-NIH Recovery Act Research Support: The random generation of T cell receptor (TCR) sequences ensures a TCR repertoire capable of recognizing a wide variety of pathogens. However, study of the TCR repertoire is hampered by this great diversity. To overcome this issue, we have used a fixed TC | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| NEVADA SYSTEM OF HIGHER EDUCATION | $72,000 | Grant | Trans-NIH Recovery Act Research Support: The goal of the parent grant was to create a database/webtool that could be used to identify minimotifs that were potentially new HIV drug targets. Minimotifs are short peptide sequences that have a known molecular function in at least one protein. The f | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $451,431 | Grant | Trans-NIH Recovery Act Research Support: In the absence of a vaccine, there is an urgent need for the development of safe and effective microbicides. Microbicides are defined as vaginally applied products that prevent transmission of HIV. Recently, we identified a short peptide called Virocide, | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| UNIVERSITY OF ILLINOIS | $18,560 | Grant | Trans-NIH Recovery Act Research Support: This supplement study is designed to train an undergraduate student for summer research experiences related to studies under the parental grant. The objective is to encourage undergraduate to pursue research careers in health-related sciences. With summ | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| UNIVERSITY OF ILLINOIS | $145,600 | Grant | Trans-NIH Recovery Act Research Support: A large segment of the female population is affected by premenstrual syndrome (PMS) and menopausal symptoms. Limited medical treatments are available, some with severe adverse effects. Instead, many women have turned to botanical dietary supplements. Ang | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $133,415 | Grant | Trans-NIH Recovery Act Research Support: This request for an administrative supplement for grant number R21 AT004661-01 is to accelerate progress in the evaluation of putative urinary peptide biomarkers of puberty discovered by initial proteomics analysis of urines obtained from the GRLS study i | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | $93,654 | Grant | Trans-NIH Recovery Act Research Support: This project includes three extensions of the Specific Aims in the parent grant. Specific Aim 1 was to obtain normative data on a diagnostic battery of language and short-term memory (STM) abilities suitable for individuals with aphasia. There are two ext | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $311,452 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplement award was to develop a strategy to heal critical size bone defects. We have formulated a new therapeutic method for accelerating the healing of calvarial defects using human fat cells. Adipose derived stromal cells (ASC) p | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF CINCINNATI | $102,218 | Grant | Trans-NIH Recovery Act Research Support: The intestinal epithelium presents a barrier to invasion of the body by undesirable luminal contents. Using both immunohistochemistry and a new in vivo method for confocal and two-photon microscopy that allows study of living villi, we find that the intes | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $34,020 | Grant | Trans-NIH Recovery Act Research Support: This Summer Undergrad Research project will have students participate in subject recruitment, data collection, database management and analysis and resporting and dissemination activities relating to the MSST trial. Students will be fully integrated into | Health and Human Services, Department of / National Institutes of Health | 6/22/2009 |
| NEW YORK UNIVERSITY (INC) | $28,000 | Grant | Trans-NIH Recovery Act Research Support: Both endothelial damage and subsequent impaired reparative function are involved in the development of various CVD, especially in the early stage. However, the biomarkers selected in parent grant are not specific or relevant to the disruption of endotheli | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $68,253 | Grant | Trans-NIH Recovery Act Research Support: Face recognition is crucial for social interaction and development, and undergoes a prolonged maturation until the teens. However, little is known about the development of the normal psychological or neural processes that support face perception in childr | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| GEORGE MASON UNIVERSITY | $10,649 | Grant | Trans-NIH Recovery Act Research Support: Parent R21 Grant: Phosphorylated Signal Pathway Proteins: A New Class of Vitreous Biomarkers for Optimizing Therapy of Wet AMD The purpose o | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $149,558 | Grant | Trans-NIH Recovery Act Research Support: One of the greatest gaps in our knowledge of human development is at the time of embryo implantation at the initiation of pregnancy, due to limitations on the experimental use of human embryos. We have recently developed a paradigm with human embryonic st | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| WASHINGTON UNIVERSITY, THE | $150,421 | Grant | Trans-NIH Recovery Act Research Support: Administrative Supplement Project Description People with diabetes and peripheral neuropathy (DM+PN) have substantial lower extremity impairments, functional limitations and disability. In addition to muscle weakness and poor balance, they also are at hig | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| DUKE UNIVERSITY | $133,600 | Grant | Trans-NIH Recovery Act Research Support: Cardiac tissue injury during myocardial infarction often leads to congestive heart failure. The field of tissue engineering offers the promise of generating a muscle patch that would structurally and functionally repair tissue damage resulting from infarc | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $8,468 | Grant | Trans-NIH Recovery Act Research Support: Administrative supplement to R21 parent grant. The parent study aimed to (1) characterize the longitudinal rate of paramedic endotracheal intubation (ETI) experience accumulation, (2) determine the diseases of patients receiving paramedic ETI and (3) iden | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $237,941 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement will be used to hire a full-time postdoctoral fellow and purchase some equipment and reagents for miR21 and ischemia-reperfusion study. This research will need additional staff to take care of mice or increase hours of curre | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| SEATTLE CHILDREN'S HOSPITAL | $25,978 | Grant | Trans-NIH Recovery Act Research Support: Ultrasound-Mediated Gene Therapy for Hemophilia B -- This proposal aims at developing ultrasound-mediated nonviral gene delivery to the liver for treatment of hemophilia and other genetic diseases. We have shown that ultrasound (US) in the presence of m | Health and Human Services, Department of / National Institutes of Health | 6/08/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $75,002 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Type 1 diabetes accounts for about 10% of all cases of diabetes and its incidence continues to increase worldwide. While newer treatment strategies have facilitated improved outcomes, the long-term microvascular compli | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $254,400 | Grant | Trans-NIH Recovery Act Research Support: Pathologies in blood vessels arising from the uncontrolled build-up of oxidized lipids contribute to atherosclerosis, a severe cardiovascular disease, which underlies the most common cause of adult death in the U.S. (exceeding one million patients yearly) | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $26,411 | Grant | Trans-NIH Recovery Act Research Support: The summer research program in our laboratory will be offered to an inner city elementary science teacher. They will conduct these experiments using established methodology in our laboratory. They will analyze data and present their findings at weekly lab | Health and Human Services, Department of / National Institutes of Health | 7/21/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $87,096 | Grant | Trans-NIH Recovery Act Research Support: Genetically encoded voltage sensors offer powerful tools for studying neural circuit activity. This grant supports research to develop the hybrid Voltage Sensor (hVOS) as a voltage imaging method in which a membrane targeted fluorescent protein is used as | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| ST LUKE'S-ROOSEVELT HOSPITAL CENTER | $157,716 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the supplement is to accelerate the pace of the scientific research in the parent grant NS061646. The overall objective of this grant, now, in its second year of funding, is to investigate the effects of antiviral drugs on HIV-1 replicatio | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $913,423 | Grant | Trans-NIH Recovery Act Research Support: This competitive revision application is in response to NOT-OD-09-058: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications and is for funds to supplement our original R24, The Rodent Gene Array Program (R-GAP). In ou | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH | $115,910 | Grant | Trans-NIH Recovery Act Research Support: Summer Fellows were employed to assist in conducting an obesity and diabetes prevention program in South Texas. | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| SAN FRANCISCO STATE UNIVERSITY | $99,965 | Grant | Trans-NIH Recovery Act Research Support: Equipment to improve and increase the capacity for tissue culture instruction for undergraduate MARC & RISE and graduate RISE and Bridge students will use the proposed tissue culture facility/lab. This laboratory would expand and update a current teachin | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $71,034 | Grant | Trans-NIH Recovery Act Research Support: This application is a request for an administrative supplement to grant 2R25GM072643-05 MUSC Minority Student Development Program (PI, Cynthia Wright). Funding is requested to support two initiatives that will increase our ability to recruit underrepresen | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| BROWN UNIVERSITY IN PROVIDENCE IN STATE OF RI AND PROVIDENCE PLANTATIONS | $125,249 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of our studies is to understand the molecular and genetic elements that underlie the process of aging and determine longevity. The aim of this proposal is to understand how mutations in a single gene, Indy, result in a dramatic increase | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| HENRY M JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY M | $170,442 | Grant | Trans-NIH Recovery Act Research Support: Escherichia coli O157:H7 is the most common infectious cause of bloody diarrhea, or hemorrhagic colitis (HC), in the U.S, and the incidence of non-O157:H7 Shiga toxin-producing E. coli (STEC) is about half that of O157:H7. Moreover, the hemolytic uremic s | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $359,936 | Grant | Trans-NIH Recovery Act Research Support: Thyroid hormone receptors (TRs) are ligand dependent, transcriptional regulators of metabolism. TRs repress gene expression in the absence of hormone, which is paradigmatic for other nuclear receptors (NRs) that function as repressors in the unliganded st | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| FLORIDA STATE UNIVERSITY, THE | $127,186 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this project is to use robotic cryo-electron microscopy to investigate the structure of the native MSP filament and one of its bound accessory proteins. The project forms part of our long term goal of understanding how cells crawl by study | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| UNIVERSITY OF MASSACHUSETTS | $91,850 | Grant | Trans-NIH Recovery Act Research Support: This is an ARRA administrative supplement to enable the Specific Aims of parent grant NIH 5 R37 GM030626 to be achieved more quickly and with greater insight. Funds have been awarded to equip an existing light microscope for Differential Interference Con | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $202,171 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The claim behind theory of mind is that certain core conceptions organize and enable our everyday understanding of the social world. In particular, social cognition is based on thinking of people in terms of their ment | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $78,803 | Grant | Trans-NIH Recovery Act Research Support: Human periventricular white matter injury (PWMI) is the major form of brain injury and the leading cause of cerebral palsy in survivors of premature birth. With advances in neonatal care, diffuse myelination disturbances and cerebral gray matter atrophy a | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| NAPROGENIX, INC. | $340,250 | Grant | Trans-NIH Recovery Act Research Support: Title: Potential anti-relapse drugs: a plant genomics approach Description: Alcohol-induced neurodegeneration and the consequent dementia are important therapeutic targets in alcoholism. However, because alcohol-induced neurotoxicity has different mechan | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| LYNCEAN TECHNOLOGIES, INC. | $2,572,551 | Grant | Trans-NIH Recovery Act Research Support: In this Competitive Grant Revision to the Fast-Track SBIR: A Compact X-ray Station for Protein Crystallography (CXS), we describe proposed enhancements and upgrades to the Compact Light Source (CLS) that will result in a substantial increase in x-ray flux | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| ARCHIVEX, LLC | $345,125 | Grant | Trans-NIH Recovery Act Research Support: This award is an Administrative Supplement to an SBIR grant. The parent grant was awarded to develop a novel means of storing, archiving and dispensing high value liquids such as DNA, antibodies, etc. while avoiding the disadvantages of contamination, ev | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| MYRIAD RBM, INC. | $92,740 | Grant | Trans-NIH Recovery Act Research Support: This award provides funding for establishment of a consortium with the University of Illinois-Chicago, Texas Children's Hospital, & Baylor College of Medicine to obtain samples necessary to complete Phase II validation of novel biomarker profiles in the b | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| TEMPLE UNIVERSITY | $98,325 | Grant | Trans-NIH Recovery Act Research Support: BCR/ABL fusion tyrosine kinase transforms HSC causing chronic myelogenous leukemia in chronic phase (CML-CP). BCR/ABL modulates the response to ?spontaneous? DNA damage to promote genomic instability. The latter may lead to resistance to tyrosine kinase i | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| PURDUE UNIVERSITY | $344,400 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Biomarker identification and characterization holds great promise for more precise diagnoses and for tailored therapies. The heterogeneity of human cancers and unmet medical needs in these diseases provides a compellin | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| HUDSON-ALPHA INSTITUTE FOR BIOTECHNOLOGY | $578,229 | Grant | Trans-NIH Recovery Act Research Support: Used assays to determine copy number aberrations in tumor and non tumor samples for three cancers glioblastoma, ovarian and lung. These funds allowed the retention of personnel to complete the project. | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| UNIVERSITY OF CINCINNATI | $592,041 | Grant | Trans-NIH Recovery Act Research Support: The vision of the University of Cincinnati Academic Health Center (AHC) Institutional CTSA is to create an environment to facilitate translating discoveries to clinical application. Our new academic home for clinical and translational research, the Center | Health and Human Services, Department of / National Institutes of Health | 8/20/2009 |
| HOWARD UNIVERSITY, INC. | $409,875 | Grant | Trans-NIH Recovery Act Research Support: To seek administrative supplement to increase the output of the parent project with increasing data collection efficiency and reliability. The parent project goal is to understand the biological roles of specific downstream signaling pathways in controll | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| NEW MEXICO STATE UNIVERSITY | $32,809 | Grant | Trans-NIH Recovery Act Research Support: Award is to used to purchase research equipment which will support eight NIH-funded porjects and an NIH supported core facility which conduct basic biomedical research at New Mexico State University. These projects also seek to engage under-represented m | Health and Human Services, Department of / National Institutes of Health | 9/10/2009 |
| SAN JOSE STATE UNIVERSITY FOUNDATION INC | $125,086 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement to the SJSU MBRS SCORE Program is being submitted under the Recovery Act in order to increase the numbers of students that graduate in STEM fields from SJSU and go on to graduate schools or the jobs in the sciences and engin | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| RFCUNY - HUNTER COLLEGE | $58,794 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement is for acquisition of a High Performance Liquid Chromatography (HPLC) System and other instrumentation, specifically a generator for the isotope rhenium-188 (Re-188), that are critical for this project. The parent project | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF TEXAS AT BROWNSVILLE | $170,941 | Grant | Trans-NIH Recovery Act Research Support: In the parent grant, SC1NS065386: Pathophysiology of the septo-hippocampal glutamatergic system, we propose to investigate the vulnerability of septal cholinergic and glutamatergic neurons to amyloid ? peptides (A?) directly injected into the medial septu | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (INC) | $131,397 | Grant | Trans-NIH Recovery Act Research Support: Individual investigator-initiated research projects for faculty at MSIs to conduct research of limited scope in environments with limited research infrastructure/facilities. | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF PITTSBURGH THE | $1,041,647 | Grant | Trans-NIH Recovery Act Research Support: BMI Training Program is requesting the addition of three predoctoral and five postdoctoral funded slots. The addition of the eight requested additional slots is consistent with the goals of ARRA funding to 'preserve and create jobs and promote economic re | Health and Human Services, Department of / National Institutes of Health | 8/20/2009 |
| FRED HUTCHINSON CANCER RESEARCH CENTER | $214,356 | Grant | Trans-NIH Recovery Act Research Support: This application seeks funding for two additional postdoctoral research fellows under the aegis of Notice NOT-OD-09-058, NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. We have identified two worthy trainees and | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $101,982 | Grant | Trans-NIH Recovery Act Research Support: This program trains predoctoral and postdoctoral fellows in the fundamentals of cancer research by participation in didactic courses, seminars, discussion groups and performance of laboratory-based research. The training program is integrated into the res | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $110,709 | Grant | Trans-NIH Recovery Act Research Support: The research portfolio at The Ohio State University College of Optometry has grown dramatically over the past ten years. This portfolio of patient-based vision research, funded through cooperative agreements and industry sources, focuses on the areas of s | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF CHICAGO, THE | $87,028 | Grant | Trans-NIH Recovery Act Research Support: The goal of this training program is to produce students with a broad multi-disciplinary background that enables them to use a variety of approaches to solve important problems in the field of neurobiology. To this end, students complete courses that span | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| THE VANDERBILT UNIVERSITY | $87,028 | Grant | Trans-NIH Recovery Act Research Support: The Molecular Biophysics Training Program at Vanderbilt involves Training Faculty exploring a wide range of problems in Molecular Biophysics using a broad spectrum of physical, chemical, and computational approaches. The main purpose of the program is to | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $38,213 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): This application requests continuing support for a training program which provides graduate students studying for the Ph.D. degree with broad state-or-the-art training in Systems and Integrative Biology. Students will | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $67,978 | Grant | Trans-NIH Recovery Act Research Support: The Rutgers/UMDNJ Biotechnology Training Program involves 28 faculty from 8 programs at two Universities. It has been providing graduate training in biotechnology to life scientists and engineers since 1989. A total of 56 students have graduated from the | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $71,602 | Grant | Trans-NIH Recovery Act Research Support: Continuing funding is requested to support 9 predoctoral trainees of the Chemistry/Biology Training Program, for the next five-years. The Training Program consists of 26 faculty members fromfour participating graduate units: Organic Division of the Chemis | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $87,028 | Grant | Trans-NIH Recovery Act Research Support: This award covers the support for one predoctoral student in the Biomolecular Pharmacology Training Program. The support is allocated for tuition, health insurance, fees, and a 12-month stipend. The trainee is engaged in an interdisciplinary curriculum an | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| THE VANDERBILT UNIVERSITY | $174,056 | Grant | Trans-NIH Recovery Act Research Support: Our training objective remains to provide trainees with a theoretical and practical base that will allow them to conduct state of the art research in basic cellular, biochemical and molecular biology. Laboratory research is the major component but overall | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| CASE WESTERN RESERVE UNIVERSITY | $253,614 | Grant | Trans-NIH Recovery Act Research Support: The ARRA Award provides supplemental funding for the Molecular Therapeutics Training Program (MTTP), specifically to support three additional trainees for the two-year period, Sept. 1, 2009 G?? Aug. 31, 2011. The global objective of the MTTP is to provid | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF CINCINNATI | $251,904 | Grant | Trans-NIH Recovery Act Research Support: The objective is to renew and increase MSTP funding for the University of Cincinnati College of Medicine (UCCOM) Physician Scientist Training Program (PSTP) which contributes well-trained physician-scientists to the national biomedical research, teaching | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON | $207,396 | Grant | Trans-NIH Recovery Act Research Support: The Division of Biostatistics at the University of Texas Health Science Center at Houston (UTHSCH) will establish a pre-doctoral training in Biostatistics, by strengthening the links between the PhD degree programs in Biostatistics and the Human Genetics | Health and Human Services, Department of / National Institutes of Health | 7/31/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $83,180 | Grant | Trans-NIH Recovery Act Research Support: The University of Virginia has developed into a top-tier research and teaching institution in the area of molecular biophysics. A key component of this effort has been the development of outstanding research training programs particularly in the areas of | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF WASHINGTON | $209,928 | Grant | Trans-NIH Recovery Act Research Support: The statistical genetics faculty at the University of Washington propose a new predoctoral training program in biostatistics that emphasizes applications to genetics. The faculty members belong to the very strong departments of Biostatistics, Genome Scien | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $87,028 | Grant | Trans-NIH Recovery Act Research Support: Lucas Ward, a graduate research assistant in the Department of Biological Sciences, is performing research on the bioinformatics of gene regulation in the laboratory of Harmen Bussemaker. Specifically, Mr. Ward is investigating the phenomenon of transcri | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $8,032,621 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): This revision application (formerly called competing supplement) to the Health and Retirement Study (NLA U01AG009740) proposes to collect and distribute the first repeat longitudinal wave of biomarker and psychosocial | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $242,026 | Grant | Trans-NIH Recovery Act Research Support: Study of Women's Health Across the nation IV: UC Davis The overall purpose of this project is to make available the SWAN body composition data obtained at follow-up exams 7-10 from dual energy xray absorptiometry (DXA) whole body scans so that the data c | Health and Human Services, Department of / National Institutes of Health | 8/15/2009 |
| UNIVERSITY OF ILLINOIS | $576,969 | Grant | Trans-NIH Recovery Act Research Support: Purposes of award: 1) Determine risks for HIV seroconversion. 2) Determine risks for HSV-2 seroincidence. 3) Analysis of results of antimicrobial resistance testing for Neisseria gonorrhoeae. 4) Conduct polymerase chain reaction assay to detect Mycopl | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| BETH ISRAEL DEACONESS MEDICAL CENTER INC | $982,867 | Grant | Trans-NIH Recovery Act Research Support: Xenotransplantation may be clinically feasible once the molecular barriers between species and mechanisms of graft loss or rejection are better understood. Xenograft survival would have to be also achieved without compromising the recipient to the extent | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $25,000 | Grant | Trans-NIH Recovery Act Research Support: Concerns about bioterrorism with variola virus and continued outbreaks of monekypox virus in Africa have resulted in the need for safer poxvirus vaccines. A detailed understanding of poxvirus complement control proteins may lead to safer live vaccinia ba | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $371,286 | Grant | Trans-NIH Recovery Act Research Support: Statistical and Data Management Center - Pediatric, Adolescent and Maternal Clinical Trial Groups - Support for Work on Residual Data from Pediatric AIDS Clinical Trials Group Studies | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $3,036,786 | Grant | Trans-NIH Recovery Act Research Support: University of North Carolina AIDS Clinical Trials Unit (UNC ACTU) - ARRA The purpose of this administrative supplement to the parent grant is to support the acceleration of the pace of the intended investigation and, as described below, to promote job cr | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| THE GEORGE WASHINGTON UNIVERSITY | $3,868,567 | Grant | Trans-NIH Recovery Act Research Support: Washington DC has among the highest HIV/AIDS rates in the United States, with a prevalence of at least 3% of the adult population. Timely and comprehensive data on the HIV/AIDS population in DC are critical in the evaluation of screening, treatment and pr | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| GLOBAL VACCINES INC | $1,069,641 | Grant | Trans-NIH Recovery Act Research Support: The impportance of the innate immune response as both the first line of defense against infection and a powerful trigger of adaptive immunity, and the definition of signaling pathways involved with this response, have led to intense testing of individual | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| UNIVERSITY OF PITTSBURGH THE | $39,590 | Grant | Trans-NIH Recovery Act Research Support: The goal of this supplement is to hire summer students or science educators for research on NIH grant award #U01AI077771 entitled Virus-Like Particle Vaccines for Pandemic Influenza. The goal of this supplement is to hire summer students or science educ | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $591,960 | Grant | Trans-NIH Recovery Act Research Support: Creatine Safety, Tolerability, and Efficacy in Huntington's Disease: CREST-E Cellular energy depletion and secondary oxidative injury are present early, even presymptomatically in Huntington's disease (HD), and play a significant role in its pathogenesis. | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| AMERICAN COLLEGE OF RADIOLOGY, THE | $3,088,082 | Grant | Trans-NIH Recovery Act Research Support: American College of Radiology Imaging Network (ACRIN) - Early Phase Imaging in Therapeutic Clinical Trials. This supplement enables ACRIN to extend its activities with respect to the development of 2 important molecular imaging agents including 18F fluoro | Health and Human Services, Department of / National Institutes of Health | 8/12/2009 |
| ST. JUDE CHILDREN'S RESEARCH HOSPITAL | $99,997 | Grant | Trans-NIH Recovery Act Research Support: To date, one must conclude that the pace of progress in disease control and preservation of functional integrity and quality of life for pediatric brain tumors remains below that of most other major types of childhood cancers. Recent advances in cellular | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| GROUP HEALTH COOPERATIVE | $491,087 | Grant | Trans-NIH Recovery Act Research Support: The Statistical Coordinating Center's (SCC) primary functions are to support the collection and analysis of data for the Breast Cancer Surveillance Consortium, develop and implement novel statistical methodology to characterize the process of breast cance | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| LOVELACE BIOMEDICAL & ENVIRONMENTAL RESEARCH INSTITUTE INC | $221,559 | Grant | Trans-NIH Recovery Act Research Support: Lung cancer is the leading cause of cancer-related deaths. The susceptibility of the chronic smoker for developing lung cancer is likely linked to germline polymorphisms in cribioactivation, detoxification and repair of DNA damage stemming from tobacco c | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| GROUP HEALTH COOPERATIVE | $223,172 | Grant | Trans-NIH Recovery Act Research Support: Microsimulation models can be used to estimate the effect of screening and changes in population risk on colorectal cancer (CRC) outcomes, offering insights beyond those gained from either observational or randomized studies. Over the past two years, we h | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| SOUTH CAROLINA RESEARCH FOUNDATION | $145,995 | Grant | Trans-NIH Recovery Act Research Support: SOUTH CAROLINA CANCER DISPARITIES COMMUNITY NETWORKS The South Carolina Cancer Disparities Community Network (SCCDCN) proposes to enhance its capacity to continue providing cancer education within the State Baptist Young Womans Auxiliary (SBYWA) of the Wo | Health and Human Services, Department of / National Institutes of Health | 8/27/2009 |
| SOUTH CAROLINA RESEARCH FOUNDATION | $289,999 | Grant | Trans-NIH Recovery Act Research Support: SOUTH CAROLINA CANCER DISPARITIES COMMUNITY NETWORKS PROJECT DESCRIPTION: The South Carolina Cancer Disparities Community Network (SCCDCN) team proposes to enhance its capacity to continue providing cancer health education within the state of South Caroli | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| PAPA OLA LOKAHI INC | $495,804 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplemental request is to expand Cancer Patient Navigator (CPN) capacity to additional health care facilities in Hawai`i serving Native Hawaiians, including federally-qualified Community Health Centers. Our activities to accomplish t | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| NORTHWESTERN UNIVERSITY | $301,882 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplement is to provide additional funding for staff charged with coordinating BMaP and GMaP network participation and building support systems for data collection and management. | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| BOSTON MEDICAL CENTER CORPORATION | $336,981 | Grant | Trans-NIH Recovery Act Research Support: The proposal of a Community Health Educator Administrative Supplement to further support the Boston Patient Navigation Research Program seeks additional resources necessary to accelerate the scientific rigor of the program by addressing two research objec | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $742,737 | Grant | Trans-NIH Recovery Act Research Support: This award responds to RFA-CA-08-504 which is intended to continue support for Phase 1 and 2 treatment studies in adults with primary central nervous system cancers and to continue the activities that were funded initially under RFA CA-04-001. This single | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF PITTSBURGH THE | $108,109 | Grant | Trans-NIH Recovery Act Research Support: The Administrative Supplement to Look AHEAD will increase the scientific impact of Look AHEAD and retain and/or create new staff positions. Look AHEAD is a randomized, controlled, multi-center clinical trial comparing the long-term health effects of an in | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $119,179 | Grant | Trans-NIH Recovery Act Research Support: This Administrative Supplement to Look AHEAD will increase the scientific impact of Look AHEAD and retain and/or create new staff positions at each of 15 local sites and the Coordinating Center. These requests parallel the submission of requests from the | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| THE VANDERBILT UNIVERSITY | $98,248 | Grant | Trans-NIH Recovery Act Research Support: To date, the AMDCC has nearly exclusively characterized inbred laboratory mice strains to study the development diabetes nephropathy. These studies support the influence of genetic risk factors as contributing to diabetic nephropathy in these inbred lines | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $99,592 | Grant | Trans-NIH Recovery Act Research Support: CAMUS is an 11 site placebo controlled clinical trial testing the efficacy of saw palmetto in the treatment of benign prostatic hyperplasia. The CAMUS Data Coordinating Center (DCC) provides infrastructure support and is responsible for: 1. Coordinating t | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| NORTHWEST INDIAN COLLEGE FOUNDATION | $79,907 | Grant | Trans-NIH Recovery Act Research Support: The DETS (Diabetes Education in Tribal Schools) project is a collaboration of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) with the following eight Tribal Colleges and Universities (TCUs): Cankdeska Cikana Community Colleg | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| STONE CHILD COLLEGE CORPORATION | $79,488 | Grant | Trans-NIH Recovery Act Research Support: HEALTHY JOURNEY REBIRTH PROJECT: DIABETES PREVENTION PROGRAM. This program was funded to develop diabetes education curriculum for Native American populated schools. The curriculum developed has been presented to various schools in hopes of it being integ | Health and Human Services, Department of / National Institutes of Health | 9/20/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $648,601 | Grant | Trans-NIH Recovery Act Research Support: Kidney disease is one of the leading health-care costs. Despite the vital importance of the kidney to maintaining the normal physiological equilibrium of an individual, there is a relatively poor understanding of the developmental program that creates the | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $150,000 | Grant | Trans-NIH Recovery Act Research Support: The Gastroparesis Clinical Research Consortium (GpCRC), is sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) with the goal of providing an infrastructure and database that will faciliate clinical, pathophysiological | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF ROCHESTER | $75,117 | Grant | Trans-NIH Recovery Act Research Support: The overall purpose is to determine whether or not cystatin C is a useful endogenous marker of GFR in children with chronic kidney disease and whether or not it can replace formal kidney function (glomerular filtration rate) measurements. It will also ser | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $215,343 | Grant | Trans-NIH Recovery Act Research Support: This proposal extends existing activities of the PharmGKB grant, and does not introduce any new aims. We are adding a curator and a student to the task of annotating the known pharmacogenetics knowledge for (1) the top 50 selling drugs in the U.S. and (2 | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $2,400,000 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Pelvic floor disorders, such as urinary incontinence, pelvic organ prolapse, and fecal incontinence, are common and significant health-related problems for women in the United States. Outcomes following surgical and no | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $1,165,393 | Grant | Trans-NIH Recovery Act Research Support: a) DC-8484958: All MONICA Fetal Heart Rate Monitors have been purchased, tested, and distributed to each of the four clinical sites. Study personnel at two of the clinical sites, Spirit Lake and Sanford Health, have been trained in using the MONICA to c | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| DM-STAT, INC | $345,067 | Grant | Trans-NIH Recovery Act Research Support: This award will allow the Prenatal Alcohol in Sudden Infant Death Syndrome and Stillbirth (PASS) Network to expand into additional sites and collect fetal heart rate data using the Monica device in the Northern Plains (Sanford Health, Pine Ridge Indian He | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON | $533,968 | Grant | Trans-NIH Recovery Act Research Support: This is an administrative supplement, to a parent award which investigates the interaction between genetic variation and modifiable environments in the determination of incident coronary heart disease (CHD). The investigator's percent effort and salary s | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| RESEARCH TRIANGLE INSTITUTE | $872,224 | Grant | Trans-NIH Recovery Act Research Support: This supplemental funding will extend and enhance communication, coordination and outreach efforts under way to develop a set of consensus standard measures used in genetic/genomic research to describe various phenotypes and exposures (the PhenX project). | Health and Human Services, Department of / National Institutes of Health | 7/30/2009 |
| SYRACUSE UNIVERSITY | $225,516 | Grant | Trans-NIH Recovery Act Research Support: This multisite project provides a unique test of a multilevel HIV/STD prevention strategy for high-risk youth. A total of 1600 African American adolescents, ages 12-16, will be recruited through CBOs in 4 cities, two in the Northeast (Providence and Syrac | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $32,129 | Grant | Trans-NIH Recovery Act Research Support: This study continues a program of research that identifies effective safe sex media messages for African American adolescents at high risk for sexually transmitted infections (including HIV). Our research indicates that such messages can be effective whi | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| TOURETTE SYNDROME ASSOCIATION, INC. | $1,701,689 | Grant | Trans-NIH Recovery Act Research Support: The focus of this competing continuation proposal is the localization and characterization of susceptibility genes for Tourette's Disorder (TD) and related conditions. The investigators are members of a longstanding international collaboration, the Touret | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| NSABP FOUNDATION, INC. | $69,847 | Grant | Trans-NIH Recovery Act Research Support: The American Cancer Society estimated that in 2004, breast or colorectal cancer would strike over 350,000 Americans and close to 100,000 people would die from these diseases. The National Surgical Adjuvant Breast and Bowel Project(NSABP) is a multi-center | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| DANA-FARBER CANCER INSTITUTE, INC. | $43,629 | Grant | Trans-NIH Recovery Act Research Support: This application requests six years of support for the ECOG Statistical Center. It is a combined narrative for the separate awards for the Statistical Office and the Data Management Office. The objectives of the Statistical Center are to provide leadershi | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| MAYO CLINIC | $797,973 | Grant | Trans-NIH Recovery Act Research Support: The specific aims of the North Central Cancer Treatment Group (NCCTG) are: 1. to improve the duration and quality of life of cancer patients by performing high-quality multidisciplinary cancer treatment trials, 2. to improve the understanding of cancer bi | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $800,000 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The Southwest Oncology Group is an adult, multi-disease, multi-modality clinical cancer research organization with 35 Member Institutions, 29 Community Clinical Oncology Program (CCOP) institutions, including 7 Minorit | Health and Human Services, Department of / National Institutes of Health | 8/12/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON | $290,035 | Grant | Trans-NIH Recovery Act Research Support: Retinopathy of prematurity (ROP) is a potentially blinding disease of premature infants in which retinal blood vessels fail to develop properly. A multicentered clinical trial (CRYO-ROP Study) sponsored by the National Eye Institute demonstrated that peri | Health and Human Services, Department of / National Institutes of Health | 8/12/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $318,479 | Grant | Trans-NIH Recovery Act Research Support: The goal of this Supplement is to provide funds for the hiring of an additional research nurse coordinator in order to facilitate the implementation of multiple research protocols. As noted, the RMN now has multiple protocols implemented, all of which are | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| BAYLOR COLLEGE OF MEDICINE | $289,704 | Grant | Trans-NIH Recovery Act Research Support: The award will provide for continuation of ongoing activities of the PPRU. The Supplemental Funding allows for the continuation and completion of ongoing PPRU projects begun during the past five | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| WAYNE STATE UNIVERSITY (INC) | $290,432 | Grant | Trans-NIH Recovery Act Research Support: This submission represents a request for an Administrative Supplement pursuant to NIH Notice Number NOT-OD-09-056 to the NIH/NICHD grant U10 HD-39005 entitled G?Cooperative Reproductive Medicine NetworkG? (PI: Michael P. Diamond, MD). As the name implies, | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF UTAH, THE | $246,140 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): This is an application to become a member of the NICHD Pediatric Pharmacology Research Unit Network to increase the study of medications in pediatric subjects, increase understanding of developmental changes in drug me | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $79,610 | Grant | Trans-NIH Recovery Act Research Support: Supplemental Request to 2U19AI057229-06 under NOT-OD-060: Recovery Act Funds for Administrative Supplements Providing Summer Research Experiences for Students and Science Educators The purpose of this supplemental request is to ask for funding for 4 stude | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| ROCKEFELLER UNIVERSITY FACULTY AND STUDENTS CLUB INC, THE | $384,124 | Grant | Trans-NIH Recovery Act Research Support: In contrast to rare Mendelian diseases, where traditional uni-variate statistical methods have successfully identified genetic risk factors, the more common complex diseases require multivariate approaches to avoid risk factors that affect only sub-popula | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| UNIVERSITY OF PITTSBURGH THE | $997,916 | Grant | Trans-NIH Recovery Act Research Support: The proposed supplement will substantially enhance the ability of the CTSA at the University of Pittsburgh to foster and conduct comparative effectiveness research, which will improve the translation of scientific discovery into clinical use, and provide | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| THE VANDERBILT UNIVERSITY | $300,240 | Grant | Trans-NIH Recovery Act Research Support: The Collaborative to Build Community Capacity for Research is a joint project of Vanderbilt University Medical Center, Meharry Medical College, and Tennessee State University which proposes to create sustainable mechanisms and processes to develop and enh | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF IOWA, THE | $295,886 | Grant | Trans-NIH Recovery Act Research Support: An essential element of the RFA entitled Institutional Clinical and Translational Science Award, CTSA, is the creation of an academic home that is a department, center, or institute. In response to the RFA, the University of Iowa will create The Universit | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $797,500 | Grant | Trans-NIH Recovery Act Research Support: Idiopathic Generalized Epilepsy (IGE) is one of the most common forms of epilepsy, representing about 30% of all epilepsies; and, its etiology is considered to be mostly genetic. Both linkage and association studies have identified several candidate genes | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | $522,955 | Grant | Trans-NIH Recovery Act Research Support: Children undergo many medical procedures that are anxiety provoking and painful. Research is accumulating to suggest that there are not only immediate but also delayed repercussions to untreated pediatric pain. Parents and medical personnel experience co | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF NEBRASKA | $533,941 | Grant | Trans-NIH Recovery Act Research Support: Articular cartilage, the avascular tissue that covers the ends of synovial joints and provides articulating joints with a durable, weight-distributing surface, damaged by illness or trauma has little capacity for self-repair. Current interventions that in | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| UNIVERSITY OF ROCHESTER | $537,562 | Grant | Trans-NIH Recovery Act Research Support: This Science Education Partnership Award (SEPA) supplement grant will support broader dissemination and adoption of our SEPA-funded curriculum modules.-? It will also provide opportunities for increasing the involvement of scientists in bringing informati | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $270,000 | Grant | Trans-NIH Recovery Act Research Support: The objective of the Global Health Framework Program is to develop multidisciplinary curricula and training program in global health through an organized effort among various entities across the campus. Specially, we will develop new multidisciplinary cur | Health and Human Services, Department of / National Institutes of Health | 5/06/2009 |
| UNIVERSITY OF MONTANA SYSTEM | $1,123,728 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this R21/R33 investigation is to satisfy the critical unmet norepinephrine transporter (NET) tracer need. The investigation will afford candidate NET Positron emission Tomography (PET) imaging agents with unique in vitro structure-activity | Health and Human Services, Department of / National Institutes of Health | 7/21/2009 |
| UNIVERSITY OF FLORIDA | $35,475 | Grant | Trans-NIH Recovery Act Research Support: Prior research indicates pervasive racial/ethnic disparities in quality of care among nursing home residents. This study proposes to examine how nursing home residents' race, nursing home segregation and residential segregation influence quality of care i | Health and Human Services, Department of / National Institutes of Health | 9/19/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $498,939 | Grant | Trans-NIH Recovery Act Research Support: The new NIH Toolbox is an assessment battery developed to standardize evaluations in specific clinical populations for investigations of neurological development and change, disease recovery, and therapeutic interventions. The Toolbox integrates a wide v | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| EMORY UNIVERSITY | $1,000,000 | Grant | Trans-NIH Recovery Act Research Support: New Frontiers in OMPD: Stem Cell Theory of Oculopharyngeal Muscular Dystrophy The Challenge: Oculopharyngeal muscular dystrophy (OPMD) is a rare autosomal dominant disease of late onset for which no cure exists. It is characterized by eyelid drooping, d | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF TEXAS M D ANDERSON | $892,724 | Grant | Trans-NIH Recovery Act Research Support: The MENTORS project will make a crucial contribution to biomedical research and public health by enhancing recruitment of minority and underserved students into scientific and clinical careers. Furthermore, many rural areas in Texas are medically underser | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $932,479 | Grant | Trans-NIH Recovery Act Research Support: TITLE: Use of Electronic Protocols to improve provider and client adherence. The Integrated Management of Childhood Illness protocols have been adapted and deployed in over 100 countries and a vast body of evidence indicates that millions of preventable d | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON | $375,255 | Grant | Trans-NIH Recovery Act Research Support: Toxins, pathogenic infection (viral and bacterial), and physical injury to the liver results in a loss of hepatic tis- ue, triggering a regenerative response to restore liver cell mass. Dysregulation in the repair process can lead o liver failure or liver | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $214,710 | Grant | Trans-NIH Recovery Act Research Support: Genetic analyses of humans with GnRH deficiency (Kallmann's Syndrome [KS] and normosmic idiopathic hypogonadotropic hypogonadism [nIHH]) have provided unique insights into the genes controlling sexual maturation (KAL1, GNRHR, FGFR1, and GPR54). The discov | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $6,396 | Grant | Trans-NIH Recovery Act Research Support: The Summer Research Experience for Students and Educators award funded 2.5 undergraduates to work on a larger 5-year project investigating the development of numerical cognition. This parent project aims to characterize the foundational Approximate Number | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| UNIVERSITY OF WASHINGTON | $147,470 | Grant | Trans-NIH Recovery Act Research Support: The seminal fluid proteins of Drosophila melanogaster have been extensively studied and are known to play a critical role in male and female reproductive success (1). Most fly seminal fluid proteins are accessory proteins (Acps), which are produced in a | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| THE VANDERBILT UNIVERSITY | $140,616 | Grant | Trans-NIH Recovery Act Research Support: Insomnia is a major comorbidity in children with autism spectrum disorders ??ASD??, and one of the most common medical concerns expressed by parents of these children. Improving sleep in this population holds promise for ameliorating many of the associate | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $99,986 | Grant | Trans-NIH Recovery Act Research Support: Whether Fc3RIIb (RIIb) of the mouse yolk sac (YS) protects the conceptus from IgG-mediated allograft rejection, the focus of this application, has evolved from our long term interest in how the human placenta handles maternal IgG antibody. The human place | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| WAYNE STATE UNIVERSITY (INC) | $123,074 | Grant | Trans-NIH Recovery Act Research Support: Protein interactions mediate most biological processes. The long-term objective of this project is to construct a high quality comprehensive protein-protein interaction map for the model organism, Drosophila. Progress on this project has shown that this d | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $352,224 | Grant | Trans-NIH Recovery Act Research Support: Our ability to identify the majority of exons in the human genome has been dramatically facilitated by the availability of extensive experimental data (EST, cDNA, and protein sequences) thereby providing training sets for the development of effective algo | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| VIRGINIA COMMONWEALTH UNIVERSITY | $147,725 | Grant | Trans-NIH Recovery Act Research Support: This supplement falls in the NHGRI ARRA category The development and application of statistical and computational data analysis methods. The goal of the parent grant Design and analysis of adaptive multistage genetic association studies 1R01HG004240 PI Va | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $33,962 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this proposal is to provide undergraduate students with an interest in public health, genetics, and bioethics, an opportunity to work on a diverse research team that is tackling a challenging problem in public health genetics. Using sound | Health and Human Services, Department of / National Institutes of Health | 5/31/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $830,000 | Grant | Trans-NIH Recovery Act Research Support: 'The purpose of this project is to gain a better understanding of aspects of host immunity that govern antibody immunity to pneumococcal disease, in particular serotype three (ST3) (pneumococcal) pneumonia. There is an urgent need for better vaccines and | Health and Human Services, Department of / National Institutes of Health | 5/06/2009 |
| MISSOURI SYSTEM, UNIVERSITY OF | $129,963 | Grant | Trans-NIH Recovery Act Research Support: In our original proposal, we set out to adapt genetic tools for working with the Category A select agent pathogen Yersinia pestis such that the use of antibiotic resistance markers could be reduced or eliminated. This research is necessary to enable progr | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $454,010 | Grant | Trans-NIH Recovery Act Research Support: 'The immediate goal of this proposal is to elucidate the role of calcium/ calmodulin-activated calcineurin phosphatase in cell signaling. Our long term goal is to define the regulation and function among interplays of calcium signaling networks. Here, we | Health and Human Services, Department of / National Institutes of Health | 5/04/2009 |
| BAYLOR RESEARCH INSTITUTE, THE | $1,600,000 | Grant | Trans-NIH Recovery Act Research Support: Vaccination represents one of the major successes of medicine as it has spared countless people from polio, tetanus and other acute infections. Yet, improved immunization strategies are needed to make vaccines for microbes that cause considerable morbidit | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| DANA-FARBER CANCER INSTITUTE, INC. | $598,870 | Grant | Trans-NIH Recovery Act Research Support: While worldwide eradication of smallpox represents a major accomplishment of medicine in the 20th century, use of this virus as a bioterrorism agent against our largely disease-susceptible civilian population could result in unprecedented mortality. Indiv | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| FRED HUTCHINSON CANCER RESEARCH CENTER | $299,969 | Grant | Trans-NIH Recovery Act Research Support: Data generated through this award indicate that MSC have no identifiable radio-protective effects in the canine model (Mielcarek et al., Biol Blood and Marrow Transplant, 2010). Therefore, initially in collaboration with Project 6 of this grant, we contin | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| WASHINGTON UNIVERSITY, THE | $1,976,256 | Grant | Trans-NIH Recovery Act Research Support: Influenza viruses are among the most frequent causes of severe respiratory illness, and new influenza viruses continue to cause re-emerging and newly emerging disease that resists established vaccines. Since existing therapy is unsatisfactory, we develope | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| BAYLOR COLLEGE OF MEDICINE | $3,184,099 | Grant | Trans-NIH Recovery Act Research Support: PURPOSE: Enhancement of the capabilities of the NURSA to generate and disseminate nuclear receptor and coregulator datasets and methodologies of a more translational character. ABSTRACT: Define the temporal and spatial physiology of Nuclear Receptors | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| THE VANDERBILT UNIVERSITY | $402,331 | Grant | Trans-NIH Recovery Act Research Support: This is an application for an administrative supplement to the Vanderbilt Program of the Clinical Proteomic Technologies Assessment for Cancer (CPTAC) in response to NIH announcement number RFA-OD-09-056 G?Availability of Recovery Act Funds for Administra | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF CINCINNATI | $243,994 | Grant | Trans-NIH Recovery Act Research Support: This proposal, from a group of established scientists at the University of Cincinnati is in response to RFA DK-00-014 to continue funding for one of five NIH-funded Mouse Metabolic Phenotyping Centers with the mission of providing phenotyping services rel | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| THE VANDERBILT UNIVERSITY | $527,577 | Grant | Trans-NIH Recovery Act Research Support: Experiments conducted by the Vanderbilt Mouse Metabolic Phenotyping Center (VMMPC) Cell Imaging Shared Resource have demonstrated our ability to measure blood cell and plasma flows in vivo with sub-om spatial and -10 msec temporal resolution. The unique a | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $246,555 | Grant | Trans-NIH Recovery Act Research Support: A Carolina Center to Characterize and Maintain Mutant Mice (ARRA)3U42RR014817-10S1 The laboratory mouse is the premier genetic model for modeling human disease. With continuing advances in gene targeting, engineering mouse mutants has become a staple in b | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| MEHARRY MEDICAL COLLEGE | $272,047 | Grant | Trans-NIH Recovery Act Research Support: This supplement to Meharry Medical College's cancer center grant will provide funds to plan for the systematic collection of biospecimen tissues in the southern region of the US. | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| CHARLES DREW UNIVERSITY OF MEDICINE AND SCIENCE | $961,177 | Grant | Trans-NIH Recovery Act Research Support: On behalf of the 18 Research Centers in Minority Institutions (RCMI), Charles R. Drew University submits this application to design and implement the RCMI Translational Research Network (RTRN or Network). The successful translation of research findings to | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| CHARLES DREW UNIVERSITY OF MEDICINE AND SCIENCE | $540,272 | Grant | Trans-NIH Recovery Act Research Support: On behalf of the 18 Research Centers in Minority Institutions (RCMI), Charles R. Drew University submits this application to design and implement the RCMI Translational Research Network (RTRN or Network). The successful translation of research findings to | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| CHARLES DREW UNIVERSITY OF MEDICINE AND SCIENCE | $382,549 | Grant | Trans-NIH Recovery Act Research Support: The primary goal of this Research Center for Minority Institutes-Clinical Research Infrastructure Initiative (RCMI-CRC) supplement is to conduct a pilot study aimed at evaluating the impact of ExerGaming (a term used to describe the integration of exercis | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $557,157 | Grant | Trans-NIH Recovery Act Research Support: One of medicine's greatest challenges today is the efficient, seamless translation of biomedical research discoveries into clinical applications. New methodologies, technologies and integrated information systems offer unprecedented promise for discovery | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $399,388 | Grant | Trans-NIH Recovery Act Research Support: One of medicine's greatest challenges today is the efficient, seamless translation of biomedical research discoveries into clinical applications. New methodologies, technologies and integrated information systems offer unprecedented promise for discovery | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF PITTSBURGH THE | $82,333 | Grant | Trans-NIH Recovery Act Research Support: Our current R21 grant, issued by NCCAM, Acupuncture for the Treatment of Insomnia - A Pilot Study, is investigating the potential benefit of acupuncture for individuals with chronic insomnia. This supplementary award will allow the study team to assess su | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | $213,114 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of this research is to decrease the morbidity and mortality related to diabetic vascular complications by developing bioactive therapeutic agents. Hyperglycemia-induced vascular inflammation, leading to monocyte adhesion to vascular end | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF MARYLAND | $139,842 | Grant | Trans-NIH Recovery Act Research Support: High-dose chemotherapy and autologous stem cell transplantation (ASCT) provides myeloma patients with the best opportunity for complete remission and long-term survival. However, relapses are common and the likelihood of cure is probably no better than 10 | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| WAYNE STATE UNIVERSITY (INC) | $83,245 | Grant | Trans-NIH Recovery Act Research Support: The goal of this project is to develop an ACES rat model of tinnitus suppression. In Aim 1, we will test the hypothesis that ACES suppresses noised-induced tinnitus in rats. To test this hypothesis, we will implant chronic electrode arrays in the rat audi | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| OKLAHOMA STATE UNIVERSITY | $18,333 | Grant | Trans-NIH Recovery Act Research Support: About 400 million people worldwide suffer from one or other type of bladder disease. Bladders can be ravaged by cancer, birth defects, nerve damage or trauma. When conservative therapies are not effective, bladder augmentation or urinary diversions are re | Health and Human Services, Department of / National Institutes of Health | 6/26/2009 |
| UNIVERSITY OF CALIFORNIA, SANTA BARBARA | $77,733 | Grant | Trans-NIH Recovery Act Research Support: The overall purpose of this ARRA supplement is to implement our research protocol in two new sites. This research protocol estimates the effects of nutritional information printed on restaurant receipts on consumers? ordering behavior by randomly assigni | Health and Human Services, Department of / National Institutes of Health | 9/10/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $281,357 | Grant | Trans-NIH Recovery Act Research Support: This supplement is used to cover the salary of a senior postdoc candidate who was adversely affected by the economic crisis and lack of job opportunities. Additional funds were requested for equipment needed to perform the research. The work should allow | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $338,872 | Grant | Trans-NIH Recovery Act Research Support: The goal of this research is to develop and validate a method using Laser Speckle Imaging to measure the intrinsic biomechanical properties of atherosclerotic plaques. The rupture of unstable atherosclerotic plaque, the most frequent event leading to thro | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $134,000 | Grant | Trans-NIH Recovery Act Research Support: The UCSD Digestive Diseases Research Development Center was awarded an ARRA supplement of $134,000. The Center has purchased, consistent with the proposal, a Cell ZScope (Biometrology), a Wire Monograph System (DMT), an AD Instruments ML870/P PowerLab wit | Health and Human Services, Department of / National Institutes of Health | 7/21/2009 |
| RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (INC) | $158,441 | Grant | Trans-NIH Recovery Act Research Support: Individual investigator-initiated pilot research projects for faculty at MSIs to generate preliminary data for a more ambitious research project. | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| HOWARD UNIVERSITY, INC. | $133,635 | Grant | Trans-NIH Recovery Act Research Support: Role for Glycosphingolipids in Regulatory Mechanisms of Neuron Development. The Research will help understand the mechanisms involved in normal brain development and provide insight into the ever-increasing numbers of developmental brain desorders where m | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| UNIVERSITY AUXILIARY AND RESEARCH SERVICES CORPORATION | $67,216 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The purpose of this application for an ARRA Non-competitive Administrative Supplement is to purchase a single piece of equipment, a SpectraMax M5 multi-mode (absorbance/fluorescence/luminescence) microplate reader. Thi | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| NEW MEXICO STATE UNIVERSITY | $134,483 | Grant | Trans-NIH Recovery Act Research Support: This is an administrative supplement application for 1SC3GM084809. The title of the parent grant is G?Chelators for iron (III) for therapeutic uses and probing cellular iron transportG?. Funding is be used to hire a full-time research technician to wor | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| NORTH CAROLINA AGRICULTURAL AND TECHNICAL STATE UNIVERSITY | $304,814 | Grant | Trans-NIH Recovery Act Research Support: MBRS Research Initiative for Scientific Enhancement at North Carolina A and T State University. The primary aim of the Administrative Supplement is to enhance student preparedness for academic and research success in the biomedical sciences during their | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| JACKSON STATE UNIVERSITY | $137,894 | Grant | Trans-NIH Recovery Act Research Support: Mississippi has the twin distinctions of being both the poorest and most disease-prone state in the nation. The state has the lowest per capita income and the highest death rate from cardiovascular disease, the leading cause of death across the state. Mis | Health and Human Services, Department of / National Institutes of Health | 6/03/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $130,414 | Grant | Trans-NIH Recovery Act Research Support: Cultural gaps between scientists and school educators have hampered the direct transfer of groundbreaking research to schools, teachers, and students. Teachers are a potential bridge to close this gap, but all too often, they are intimidated by rapid adva | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| EAST CAROLINA UNIVERSITY | $198,563 | Grant | Trans-NIH Recovery Act Research Support: Under the operations of the parent grant, the FoodMASTER Science Education and Dissemination supplement will 1) provide workshops and implementation materials to a total of 100 teachers at 3 regional science teacher conferences and the National Science Te | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| BROWN UNIVERSITY IN PROVIDENCE IN STATE OF RI AND PROVIDENCE PLANTATIONS | $200,000 | Grant | Trans-NIH Recovery Act Research Support: Project ARISE: Advancing Rhode Island Science Education is a professional development program for teachers designed to engage students in inquiry-based approaches to learning about science, bring cutting-edge research into the classroom, and improve the u | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| UNIVERSITY OF UTAH, THE | $200,000 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Project Summary: The Genetic Science Learning Center (GSLC) at the University of Utah will utilize its synergistic expertise in education, science and technology to educate secondary-level life science students and tea | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| AR CHILDRENS HOSPITAL RESEARCH INSTITUTE | $207,139 | Grant | Trans-NIH Recovery Act Research Support: The primary purpose of this request for supplement funding is to expedite the completion of ongoing study activities for 10 studies in which the ACH PPRU has active enrollment. | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $186,131 | Grant | Trans-NIH Recovery Act Research Support: The University of Colorado Reproductive Medicine Unit (UC-RMU) is uniquely positioned to be an active and valuable participant in the Cooperative Multi-Center Reproductive Medicine Network of the NICHD. This proposal is jointly submitted by the Sections o | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $220,849 | Grant | Trans-NIH Recovery Act Research Support: This supplement will augment the activities and aims supported by the parent grant (5U10HD041261). The University of Alabama at Birmingham (UAB) has been a clinical site for 9 years in the Pelvic Floor Disorders Network (PFDN), a clinical research network | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| DUKE UNIVERSITY | $264,847 | Grant | Trans-NIH Recovery Act Research Support: As part of the modENCODE consortium, we are funded to identify and characterize the functional DNA elements that direct DNA replication throughout the Drosophila genome. The goals of our project, The Systematic Identification and Analysis of Replication O | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| PALMER COLLEGE FOUNDATION | $578,853 | Grant | Trans-NIH Recovery Act Research Support: Palmer Center for Chiropractic Research (PCCR) proposes to build upon its success in developing research expertise and infrastructure by strengthening its current collaborations and formally establishing a new collaboration in a 4 year multidisciplinary g | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $618,827 | Grant | Trans-NIH Recovery Act Research Support: The innate immune system is a cooperative network of host defenses that utilizes both soluble components and cellular defenses. Central to innate immune recognition are pattern recognition receptors (PRRs) that recognize pathogen derivatives or altered-se | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH | $349,355 | Grant | Trans-NIH Recovery Act Research Support: This is an application for a Recovery Act Administrative Supplement (NOT-OD-09-056) to CPTAC grant U24CA126485, entitled ?Assessment of serum peptide profiling to detect cancer?. The supplement funds will be used to hire one additional, full-time staff m | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $492,873 | Grant | Trans-NIH Recovery Act Research Support: To respond to the needs for advanced infrastructure for collaborative biomedicine, the NCRR Biomedical Informatics Research Network (BIRN) was established to develop a federated and distributed infrastructure for the storage, retrieval, analysis, and docu | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | $415,000 | Grant | Trans-NIH Recovery Act Research Support: In the previous funding period, the Southern California Islet Cell Resources (SC-ICR) Center has established itself as one of the most productive islet transplantation centers in ICR program while also providing high quality islets to ICR-approved project | Health and Human Services, Department of / National Institutes of Health | 9/02/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $2,218,251 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this project is to extend the scientific value of the resources generated by the Knockout Mouse Project (KOMP). The overall aim of KOMP is to dramatically increase the number of unique knockout alleles crucial to many fields of translationa | Health and Human Services, Department of / National Institutes of Health | 8/24/2009 |
| UNIVERSITY OF MEDICINE AND DENTISTRY OF NJ (INC) | $432,351 | Grant | Trans-NIH Recovery Act Research Support: Diabetic retinopathy (DR) is a major ocular complication for persons with diabetes mellitus (DM), particularly for African American patients with type 1 (insulin-dependent) DM. While many of the factors involved in the etiology of DR remain to be resolved | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $424,841 | Grant | Trans-NIH Recovery Act Research Support: Recent research has shown that mortality rates increase during economic expansions and decrease during recessions. This counterintuitive finding has been replicated in several industrialized countries, but important questions remain regarding the relative | Health and Human Services, Department of / National Institutes of Health | 9/02/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $453,459 | Grant | Trans-NIH Recovery Act Research Support: In this proposal high resolution diffusion tensor imaging of the mouse brain will be developed as surrogate markers to assess the social behavioral abnormalities in mouse models relevant to autism. Successful implementation of the proposed DTI techniques | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| UNIVERSITY OF PITTSBURGH THE | $416,625 | Grant | Trans-NIH Recovery Act Research Support: Cyloxygenase-2 (COX-2), the enzyme responsible for production of prostaglandins, has been identified as an important contributor to brain damage following hypoxia-ischemia. Unfortunately, COX-2 inhibitors have been reported to cause cerebral and cardiac t | Health and Human Services, Department of / National Institutes of Health | 6/02/2009 |
| CORNELL UNIVERSITY, INC | $423,500 | Grant | Trans-NIH Recovery Act Research Support: In the central nervous system, protein isoform diversity is responsible, at least in part, for its complexity and its many orchestrated activities. This proposal concerns the role of alternative splicing in the differentiation and function of various extr | Health and Human Services, Department of / National Institutes of Health | 8/27/2009 |
| NEW YORK MEDICAL COLLEGE | $434,890 | Grant | Trans-NIH Recovery Act Research Support: We have fully completed the project. We found that levels of neurocan, brevican, aggrecan, phosphacan, and versican were elevated, whereas NG2 expression was reduced in pups and infants with IVH compared to controls. Intracerebroventricular chondroitina | Health and Human Services, Department of / National Institutes of Health | 8/27/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE | $466,125 | Grant | Trans-NIH Recovery Act Research Support: Frizzled (Fz) receptors act as signal transducers of Wnt growth factors via several effector pathways, notably Wnt/2-catenin (2-cat) and Fz/planar cell polarity (PCP) signaling. Fz/PCP and Wnt-Fz/2-cat signaling diverge downstream of the cytoplasmic facto | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $527,101 | Grant | Trans-NIH Recovery Act Research Support: Given the lack of empirically validated treatments for infants and toddlers with autism under two years of age, our goal was to develop and test a manualized, parent delivered intervention for young children symptomatic and/or at high familial risk for au | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $407,000 | Grant | Trans-NIH Recovery Act Research Support: ARRA-Role of Programmed Cell Death10 (PDCD10) in p38 MAP kinase activation and PDK1 signaling. Understanding and manipulating complex protein-protein interactions required for physiological signaling during angiogenesis and vasculogenesis is an important | Health and Human Services, Department of / National Institutes of Health | 5/15/2009 |
| UNIVERSITY OF MIAMI | $903,771 | Grant | Trans-NIH Recovery Act Research Support: This award addresses broad Challenge Area (15) Translational Science and specific Challenge Topic, 15- NS-103: Demonstration of 'Proof of Concept' for a New Therapeutic Approach in a Neurological Disease. Traumatic brain injury (TBI) is a significant heal | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| CASE WESTERN RESERVE UNIVERSITY | $834,093 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (06) Enabling Technologies and Specific Challenge Topic, 06-NS-104: Developing and validating assistive neuro-technologies. Respiratory complications account for significant morbidity and mortality in patien | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| CHILDREN'S HOSPITAL CORPORATION, THE | $999,999 | Grant | Trans-NIH Recovery Act Research Support: This grant proposal primarily addresses broad Challenge area (06) Enabling Technologies. Specifically, the proposal meets two sub-areas within this main Challenge: 06-NS-105 Importing important technologies into neuroscience; 06-NS-106 Validating new meth | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| DUKE UNIVERSITY | $6,824,989 | Grant | Trans-NIH Recovery Act Research Support: This proposal is the first step in a major paradigm shift leading to global acceptance of evidence-based protocol-driven care as the optimal approach to treatment of pediatric rheumatic diseases by families, patients, and health care providers. Through th | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $3,344,252 | Grant | Trans-NIH Recovery Act Research Support: Rheumatoid arthritis (RA) is the most common type of inflammatory arthritis; while there are now many effective medications to treat it, these drugs vary greatly in cost (up to $15,000/year) and side effects and there is no way to predict which drug is be | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| RUSH UNIVERSITY MEDICAL CENTER | $1,375,841 | Grant | Trans-NIH Recovery Act Research Support: Biotribological Layers in Metal-on-Metal Hip Replacement: The ultimate objective of this research is to improve implant longevity in metal-on-metal bearings and decrease the morbidity and cost associated with revision surgery. | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $1,814,520 | Grant | Trans-NIH Recovery Act Research Support: We introduce the second generation theranostic devices that integrate multiple targeting moieties (e.g., antibody- or aptamer-based) with two additional molecular components: (1) molecular computing in order to analyze obtained disease signatures; and (2) | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $1,000,000 | Grant | Trans-NIH Recovery Act Research Support: The goal of our project is to develop vaccine strategies that will target viral pathogens underlying the most common AIDS malignancies even in the unfavorable immunologic setting of low CD4+ T cell counts that typically characterizes HIV-infected patients | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| OHIO STATE UNIVERSITY, THE | $1,349,227 | Grant | Trans-NIH Recovery Act Research Support: The prognosis for advanced stage oral squamous cell carcinomas (oral SCCs) remains among the lowest of solid tumors. Clearly, early detection of the precursor lesion for oral SCC i.e. oral epithelial dysplasia combined with local intervention strategies, | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $3,750,000 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this project is to discover new therapeutic targets and drug leads for treating lung cancer. To do this, we have completed an analysis of 56 lung cancer cell lines and have assigned them to 6 genetically distinct clades. Two representativ | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |