Listing all stimulus spending by amount, in descending order. Return to National Institutes of Health page
Amount refers to both the amount of stimulus funding going toward the project and the face value of the loan.
| Recipient | Amount | Type | Description | Federal Dept./Agency | Date |
|---|---|---|---|---|---|
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $250,000 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION, OVERALL (provided by applicant): This is a Program Project to continue investigation of the functions and trafficking of specific liver cell membrane proteins. Four projects involving 15 faculty investigators representing 6 academic departmen | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $98,996 | Grant | Trans-NIH Recovery Act Research Support: The objective of the proposed studies is to identify the cellular signals that regulate hepatocyte death in reponse to toxic liver injury. Our general hypothesis has been that cell death is not merely a passive process resulting from the biochemical effec | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| WASHINGTON UNIVERSITY, THE | $2,000,000 | Grant | Trans-NIH Recovery Act Research Support: The current epidemic of Methicillin Resistant Staphylococcus aureus infection is a grand opportunity to apply new genetic methods to understanding this disease. There are multiple outcomes from MRSA infection, ranging from curable localized infection to d | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $1,984,285 | Grant | Trans-NIH Recovery Act Research Support: The proposed development of pharmaco-response signatures is directly relevant to NIH goals of developing better anti-cancer drugs and identifying those patients most likely to benefit from specific therapies; it also meets the Grand Opportunities (RFA-OD- | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| EMORY UNIVERSITY | $2,373,533 | Grant | Trans-NIH Recovery Act Research Support: Phase II study: Mobilization of progenitor cells in peripheral arterial disease Atherosclerotic peripheral arterial disease (PAD) of the ileo-femoral circulation is a common condition that afflicts up to 5% of the U.S. population, often resulting in seve | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $1,466,880 | Grant | Trans-NIH Recovery Act Research Support: CTRIP Ex-vivo perfusion and ventilation of lungs to assess transplant suitability This Stage 1 Grand Opportunity (GO) Research Infrastructure project will refine and perfect techniques for assessment of suitability of human lungs for lung transplant (LTX) | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF CHICAGO, THE | $7,375,208 | Grant | Trans-NIH Recovery Act Research Support: EVE is a consortium comprised of all U.S. investigators who have conducted genome-wide association studies (GWAS) of asthma and whose main objective is to combine results of individual studies to increase the overall power to identify asthma-susceptibilit | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF MARYLAND | $2,425,363 | Grant | Trans-NIH Recovery Act Research Support: The University of Maryland Baltimore is submitting this application to establish a Bioethics Center under the NCMHD ARRA Scientific priority area 'Bioethics Research Infrastructure Initiative' through 'GO' grants RFA-OD-09-004. This Bioethics Center's pro | Health and Human Services, Department of / National Institutes of Health | 9/27/2009 |
| JOINT CENTER FOR POLITICAL AND ECONOMIC STUDIES, INC. | $1,334,970 | Grant | Trans-NIH Recovery Act Research Support: 'CREATING COMMUNITY HEALTH EQUITY REPORTS TO INFORM POLICY AND PRACTICE.' The Health Policy Institute (HPI) of the Joint Center for Political and Economic Studies will prepare and disseminate a series of locally-tailored Community Health Equity reports th | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $4,180,489 | Grant | Trans-NIH Recovery Act Research Support: This research will start to identify and break down racial and ethnic communications barriers and will serve as a model that could be implemented at other cancer centers and hospitals nationwide to improve minority participation in clinical trials. While | Health and Human Services, Department of / National Institutes of Health | 9/27/2009 |
| DUKE UNIVERSITY | $3,132,972 | Grant | Trans-NIH Recovery Act Research Support: RFA-OD-09-004 Recovery Act Limited Competition for NIH Grants: Research and Research Infrastructure G?Grand OpportunitiesG? (RC2) Large-scale genetics studies on schizophrenia to date have failed to discover a substantial contribution of common genetic va | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $5,428,214 | Grant | Trans-NIH Recovery Act Research Support: This should be material from first ARRA submission. Not for sure why showing last quarter!s accomplishments. | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE | $3,761,304 | Grant | Trans-NIH Recovery Act Research Support: A tremendous amount of research energy has been dedicated to demonstrating the importance of genetic influences on developmental psychopathologies in children. To date a convincing argument can be made that all of the developmental psychopathologies are | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $1,797,515 | Grant | Trans-NIH Recovery Act Research Support: The blood-brain barrier (BBB) normally serves to protect the brain from agents that circulate in the blood. However, it also poses a major limitation to drug delivery and the large majority of drugs cannot be used in the central nervous system (CNS). Curr | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| OHIO STATE UNIVERSITY, THE | $3,354,732 | Grant | Trans-NIH Recovery Act Research Support: Spinal Muscular Atrophy (SMA) and Amyotrophic Lateral Sclerosis (ALS) are fatal motor neuron disorders for which no significant treatments currently exist. Delivery of a therapeutic agent across the blood brain barrier (BBB) to the central nervous system | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| TUFTS MEDICAL CENTER PARENT, INC. | $825,000 | Grant | Trans-NIH Recovery Act Research Support: (RO1 for new and early stage investigator) In this proposal, we test the hypothesis that aldo activation of VSMC MR induces expression of PlGF, which activates Flt-1 receptors to stimulate VSMC proliferation, macrophage recruitment, vascular inflammation, | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF PITTSBURGH THE | $103,734 | Grant | Trans-NIH Recovery Act Research Support: We requested funds for the Bio-Rad Laboratories Bio-Plex Workstation and Software (Suspension Array) system to provide a multiplex system to facilitate simultaneous analysis of up to 100 different biomolecules (proteins, peptides or nucleic acids) in a si | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| UNIVERSITY OF NEVADA, RENO | $272,458 | Grant | Trans-NIH Recovery Act Research Support: In our NIH Shared Instrumentation Grant application Acquisition of DIGE Instrumentation to Enhance Proteomic Research in Nevada, the Nevada Proteomics Center requested equipment and software that would enable our 2-D Gel Laboratory to perform differentia | Health and Human Services, Department of / National Institutes of Health | 5/01/2009 |
| NEW YORK UNIVERSITY (INC) | $438,028 | Grant | Trans-NIH Recovery Act Research Support: This proposal requests support for the purchase of a Zeiss LSM 710 confocal microscope, which will be a shared resource crucial to the work of five Major User laboratories at NYU School of Medicine as well as a valuable resource to outside users in the wi | Health and Human Services, Department of / National Institutes of Health | 5/14/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $2,000,000 | Grant | Trans-NIH Recovery Act Research Support: Live biological processes have previously only been observed by light microscopy at low spatial resolution (~200nm), while the molecular details of biological samples have only been studied at high-resolution (~1 nm) in the arrested (fixed or frozen/cryo) | Health and Human Services, Department of / National Institutes of Health | 4/28/2009 |
| UNIVERSITY OF PITTSBURGH THE | $2,000,000 | Grant | Trans-NIH Recovery Act Research Support: A clinical animal MR imager designed for translational research: the 7T Clinscan Summary: The purpose of this American Reinvestment and Recovery Act (ARRA) award is to provide funds towards the purchase of a small animal clinical magnetic resonance (MR) | Health and Human Services, Department of / National Institutes of Health | 4/28/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $495,000 | Grant | Trans-NIH Recovery Act Research Support: Proposed is the purchase of a multi-mode, multi-channel transmitter to bring new utility to our 9.4T / 65 cm bore NMR system for an increasing number of human and animal studies. In pursuit of higher signal-to-noise, increased spectral resolution, improve | Health and Human Services, Department of / National Institutes of Health | 4/28/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $310,074 | Grant | Trans-NIH Recovery Act Research Support: Instrumentation for upgrading cryoEM and single particle analysis capabilities This award provided approximately $310,000 in funds to upgrade the Lineberger Comprehensive Cancer Center's electron microscope core facility with equipment needed to carry ou | Health and Human Services, Department of / National Institutes of Health | 4/28/2009 |
| UNIVERSITY OF PITTSBURGH THE | $463,521 | Grant | Trans-NIH Recovery Act Research Support: This award funds a newly available CereTom CT scanner and related accessories which allow it to be combined with a preclinical non-human primate microPET P4 scanner in the fashion of hybrid PET/CT systems, giving a true hybrid imaging platform geared spec | Health and Human Services, Department of / National Institutes of Health | 4/28/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $449,000 | Grant | Trans-NIH Recovery Act Research Support: This project is being supported with funds from the American Recovery and Reinvestment Act, which may involve a reduction in the research aims and scope. If necessary, a revised abstract will be posted soon and this notice removed. DESCRIPTION (provided | Health and Human Services, Department of / National Institutes of Health | 4/28/2009 |
| THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | $120,000 | Grant | Trans-NIH Recovery Act Research Support: The 9.4T magnetic resonance imaging laboratory is a joint facility between Stony Brook University (SBU) and Brookhaven National Laboratory (BNL) and has been operational since 2004. The growing user group mainly includes investigators from BNL, SBU and Co | Health and Human Services, Department of / National Institutes of Health | 4/28/2009 |
| DUKE UNIVERSITY | $461,402 | Grant | Trans-NIH Recovery Act Research Support: The explosive growth of computational biology has made it difficult for research organizations to keep pace with users' demands for ever-increasing computational power. The complications that biologists face come from two developments. First, new technolo | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| SIGA TECHNOLOGIES, INC. | $1,667,535 | Grant | Trans-NIH Recovery Act Research Support: The family Bunyaviridae is comprised of a diverse group of viruses spread across five genera and infecting hosts from both the plant and animal kingdoms. Significant biothreats among these are several human pathogens including Rift Valley fever virus (RVF | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY | $1,779,809 | Grant | Trans-NIH Recovery Act Research Support: Dengue virus (DENV) causes dengue fever (DF) and dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS), the most prevalent mosquito-borne viral illnesses in humans worldwide. Studies suggest that sub-neutralizing concentrations of DENV-specific antibod | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| THE MIRIAM HOSPITAL | $726,805 | Grant | Trans-NIH Recovery Act Research Support: This project is designed to complete the scientific planning and administrative activities that are required to conduct a clinical trial on the efficacy of lifestyle intervention to treat obese men with erectile dysfunction (ED). ED is a significant publ | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $3,878,972 | Grant | Trans-NIH Recovery Act Research Support: The 4DB Center's potential impact is on two fronts, the basic research ability to conduct physical sciences experiments on cancer patient samples in a meaningful way and to generate the force and time journey of cancer cells during the metastatic phase. T | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $830,046 | Grant | Trans-NIH Recovery Act Research Support: Shigella flexneri is a bacterial pathogen responsible for serious gastrointestinal disease throughout the world. We have found that this organism has the capacity to inhibit the immune response directed against it by the host. The work we completed under | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| JOSLIN DIABETES CENTER, INC. | $807,813 | Grant | Trans-NIH Recovery Act Research Support: Title: RIPE3b1, an important insulin gene transcription factor. Diabetes results from a reduction in the amount of functional pancreatic ?+?-cells. In type 1 diabetes, reduction in ?+?-cell mass results from autoimmune attack, while in type 2 diabetes ? | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF ARKANSAS SYSTEM | $646,772 | Grant | Trans-NIH Recovery Act Research Support: The myelin proteolipid protein (PLP) gene (Plp1) encodes the most abundant protein present in CNS myelin. Its expression in oligodendrocytes is tightly regulated. Mutations in the human gene have been shown to be associated with the X-linked dysmyelinatin | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| UNIVERSITY OF MASSACHUSETTS | $828,940 | Grant | Trans-NIH Recovery Act Research Support: The Role of LPS and Toll-like Receptors in Plague, Award Number R01AI057588 from the NIH - Institute of Allergy and Infectious Diseases, is proposing to use Y. pestis strains that generate modified LPS to study evasion and activation of innate immunity by | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL | $648,000 | Grant | Trans-NIH Recovery Act Research Support: Dysregulation of the inflammatory response plays an important role in the pathogenesis of a plethora of human diseases, including inflammatory bowel disease (IBD). Mitogen-activated protein kinase phosphatase (MKP)-1 is crucial for restraining the inflamm | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| NORTH CAROLINA STATE UNIVERSITY | $207,368 | Grant | Trans-NIH Recovery Act Research Support: Transmission of HIV-1 occurs predominately at mucosal surfaces and therefore a successful vaccine against HIV-1 must induce mucosal humoral and cellular immune responses. Lactic acid bacteria have been used for centuries to process and preserve food and | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $13,648 | Grant | Trans-NIH Recovery Act Research Support: Acquired brain injuries, such as those resulting from trauma, are among the most common causes death and long-term disability in all age groups. It is unclear whether neural stem cells are responsible for some of the limited recovery that spontaneously oc | Health and Human Services, Department of / National Institutes of Health | 7/27/2009 |
| NORTH CAROLINA STATE UNIVERSITY | $166,424 | Grant | Trans-NIH Recovery Act Research Support: Annual progress report for continuing NIH training grant. This training program provides training for six graduate students at the interface of Biostatistics and Genome Science. | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $102,208 | Grant | Trans-NIH Recovery Act Research Support: The activities of proteins that control cell growth and development must be tightly controlled to prevent the spurious cell proliferation, migration, and resistance to apoptosis that are hallmarks of cancer. Regulation of these proteins is often mediated | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| HAUPTMAN WOODWARD MEDICAL RESEARCH INSTITUTE, INC. | $104,391 | Grant | Trans-NIH Recovery Act Research Support: Pneumocystis jirovecii is the causative agent of Pneumocystis pneumonia, one of the most frequent and severe opportunistic infections in immunocompromised patients, particularly those with HIV AIDS. Current treatment of Pneumocystis pneumonia combines su | Health and Human Services, Department of / National Institutes of Health | 8/12/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $41,360 | Grant | Trans-NIH Recovery Act Research Support: Award Title: Protein Transport Across Membranes The long-term goal of | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| HEALTH RESEARCH, INC. | $249,141 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The long-term goal is to understand how peptidyl-prolyl isomerases (PPIases) control important cellular processes such as transcription and mitosis. PPIases catalyze the cis/trans isomerization of the peptide bond that | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| WILLIAM MARSH RICE UNIVERSITY | $234,951 | Grant | Trans-NIH Recovery Act Research Support: We propose to study membrane-active proteins and peptides that cause configurational changes in cell membranes, including pore formation and membrane fusion. Pore-forming peptides are animals' (including human's) gene-encoded innate antimicrobials that ki | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| TRUSTEES OF TUFTS COLLEGE INC | $271,117 | Grant | Trans-NIH Recovery Act Research Support: Using a tumor virus, we are defining the events that occur during the initiation of DNA replication. Initiation of DNA replication is a complicated process that is known to take place in many stages; these include the recognition of the viral origin by th | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| PENNSYLVANIA STATE UNIVERSITY, THE | $284,673 | Grant | Trans-NIH Recovery Act Research Support: The regulation of gene expression is a fundamental process in cells, and alterations in this process have been linked to numerous disease states in humans. It is regulated at multiple levels, requiring highly coordinated and integrated events including ch | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| PENNSYLVANIA STATE UNIVERSITY, THE | $432,061 | Grant | Trans-NIH Recovery Act Research Support: Human health is highly dependent upon proper gene expression. Understanding how genes are regulated is critical in our understanding how mis- regulation leads to diseases. One major point where genes are regulated is during the assembly of the transcripti | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $257,501 | Grant | Trans-NIH Recovery Act Research Support: Our long-term goal is to understand the function and regulation of cellular RNA polymerase (RNAP) in molecular detail. Bacteriophages evolved elaborate mechanisms to regulate transcription of bacterial host to serve viral needs. The number of phage-encode | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $247,275 | Grant | Trans-NIH Recovery Act Research Support: We propose to study chimeras of MscL orthologues with distinct functional characterists. In addition, we propose to define potential changes in protein-lipid (or other hydrophobic) interactions that occur upon MscL gating by screening a cysteine library | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF CONNECTICUT | $184,773 | Grant | Trans-NIH Recovery Act Research Support: Intracellular transport of organelles and particles is ubiquitous in animal cells and has fundamental importance for such diverse processes as secretion, neuronal signaling, organization of endomembranes,and cell division. The driving force for intracellu | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $514,960 | Grant | Trans-NIH Recovery Act Research Support: Our recent studies have suggested that phosphate is an accelerator of aging. The purpose of this supplement is to test if aging processes can be suppressed by low phosphate diet and accelerated by high phosphate diet in a mouse model of aging. If succes | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF MEDICINE AND DENTISTRY OF NJ (INC) | $155,276 | Grant | Trans-NIH Recovery Act Research Support: The overall hypothesis in this research supplement proposal is that Nox4 in VSMCs and ECs plays an important role in mediating oxidative stress in the vasculature and regulating blood pressure in mice. A major goal is to elucidate the basic function of No | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO | $72,138 | Grant | Trans-NIH Recovery Act Research Support: Holzenberger et al (2003) recently reported that mice heterozygous for the IGF-I receptor gene in all tissues (Igflr^' mice) have extended life span in association with resistance to paraquat toxicity. This finding would be seminal since it shows that the | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE | $121,248 | Grant | Trans-NIH Recovery Act Research Support: Elderly patients who undergo anesthesia and non-cardiac surgery are subject to deterioration of brain function including the development of postoperative delirium (PD) and postoperative cognitive dysfunction (POCD). These disorders cause disability, distr | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $239,179 | Grant | Trans-NIH Recovery Act Research Support: Our original proposal involved analyzing changes in transthyretin structure with aging and how the liver, its site of production, protected both itself and distant organs from damage produced by the misfolded molecule and the effects of transthyretin depo | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $22,422 | Grant | Trans-NIH Recovery Act Research Support: This amended application seeks support for new work aimed at the treatment of vascular aging in humans. The proposed research will determine if habitual aerobic exercise improves endothelium-dependent dilation (EDD), a clinically important marker of vascu | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| BAYLOR COLLEGE OF MEDICINE | $179,595 | Grant | Trans-NIH Recovery Act Research Support: We are submitting this application in response to the Recovery Act Administrative Supplement (NOT-OD-09-056) to the parent grant RO1 AG032135 entitled G?Epigenetic Regulation of Cell and tissue AgingG? (09/30/2007-08/31/2012. The objective of the parent g | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| EMORY UNIVERSITY | $195,000 | Grant | Trans-NIH Recovery Act Research Support: MHC Class II Transactivator Function and Regulation This supplement will extend the work that was begun as Aim 2 in AI34000-15. Major histocompatibility complex (MHC) molecules represent the major barrier to organ transplantation. As such, understanding t | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| IOWA STATE UNIVERSITY | $51,710 | Grant | Trans-NIH Recovery Act Research Support: Infections by the Ebola virus can cause severe viral hemorrhagic fever resulting in the suppression of host innate and adaptive immune systems. The Ebola virus inhibits host interferon (IFN) activities in order to replicate, thus resulting in serious dis | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| CARNEGIE MELLON UNIVERSITY | $92,824 | Grant | Trans-NIH Recovery Act Research Support: Biofilm formation has a major impact on human health as the underling cause of medical device-associated infection, which causes systemic infections that often prove fatal. Our study focuses on C. albicans and C. parapsilosis, which are the major contribu | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| CAPITAL TECHNOLOGY INFORMATION SERVICES, INC. | $2,468,393 | Contract | : ACTNOW (Accelerating Clinical Trials of Novel Oncology PathWays) Clinical Trial Support under Operation and Support of the Cancer Therapy Evaluation Program's Informatic and Computer Support. Activities will include Help Desk Support, Operations Support, | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| CABEZON GROUP, INC | $472,484 | Contract | : Award covers the performance of clinical trials support tasks for the Accelerating Clinical Trials of Novel Oncologic PathWays project. | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| LOGICAL TECHNICAL SERVICES CORP. | $147,000 | Contract | : Provide technical writers to review grant applications in response to ARRA. | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| GOVERNMENT SCIENTIFIC SOURCE, INC. | $58,723 | Contract | : Item 1:Bio-Plex 200 System with HTF Part# BIO RAD 171000205 1@$58,723.40 | Health and Human Services, Department of / National Institutes of Health | 9/17/2010 |
| LOUVIERE, STRATTON & YOKEL, L.L.C. | $10,144,513 | Contract | : Provide post design Services for Building 10 E & F Wings - Phase B1 & B2. | Health and Human Services, Department of / National Institutes of Health | 5/13/2009 |
| STERLING COMPUTERS CORPORATION | $46,224 | Contract | : ADP Hardware Equipment | Health and Human Services, Department of / National Institutes of Health | 6/24/2009 |
| RESEARCH FOUNDATION FOR MENTAL HYGIENE INC | $10,496,230 | Contract | : To design and test a method of intervention that has the capacity to promote engagement and adherence to treatment, foster recovery and reduce or prevent disability in patients experiencing a first episode of schizophrenia and related psychotic disorders. | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| RANGER GROUP LLC, THE | $3,156,848 | Contract | : Recovery Act -- Repair & Upgrade Switchgear -- Building 52 | Health and Human Services, Department of / National Institutes of Health | 4/28/2009 |
| RANGER GROUP LLC, THE | $3,983,641 | Contract | : Recovery Act -- Repair & Upgrade Switchgear -- Building 31A | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF IOWA, THE | $658,627 | Grant | Trans-NIH Recovery Act Research Support: Our general aim is to discover how the brain processes visual information, how neural activity is related to visual perception, and how visual processing interacts with other brain systems underlying cognition. Our specific aim is to elucidate how pigeons | Health and Human Services, Department of / National Institutes of Health | 9/02/2009 |
| MISSOURI SYSTEM, UNIVERSITY OF | $707,406 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Wild-type (WT) and IL-4-/- NOD.H-2h4 mice given 0.05% NaI water develop lymphocytic spontaneous autoimmune thyroiditis (L-SAT) with B and T cell infiltration of the thyroid, and production of anti-thyroglobulin antibod | Health and Human Services, Department of / National Institutes of Health | 5/28/2009 |
| MISSOURI SYSTEM, UNIVERSITY OF | $50,304 | Grant | Trans-NIH Recovery Act Research Support: This is a proposal for a supplement to fund three undergraduate students to work in the lab during the summers of 2009 and 2010. These students will accelerate the tempo of the science while learning valuable laboratory procedures. Hopefully, they will | Health and Human Services, Department of / National Institutes of Health | 6/30/2009 |
| ORACLE AMERICA, INC. | $1,554,545 | Contract | : Oracle Consulting Services for the NIH Business System's Oracle Governance Risk, and Compliance Controls Suite. | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| MASTER KEY RESOURCES, LLC | $1,195,800 | Contract | : The purppose of this task order is to acquire additional grant supporting staff for DEAS using Recovery Act funds under the existing competetively awarded, small business set-aside task order. | Health and Human Services, Department of / National Institutes of Health | 6/19/2009 |
| FISHER SCIENTIFIC COMPANY L.L.C. | $231 | Contract | : Laboratory & hospital supplies | Health and Human Services, Department of / National Institutes of Health | 6/16/2009 |
| WYLE INFORMATION SYSTEMS, LLC | $146,445 | Contract | : Provide support for the OPERA Interface with GM Module that will significantly improve the quality and accuracy of awards, reduce the number of revised awards currently needed when errors are noted, and significantly reduce the administrative burden for b | Health and Human Services, Department of / National Institutes of Health | 9/26/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $332,000 | Grant | Trans-NIH Recovery Act Research Support: This supplement funds, in part, three pilot projects that combine the distinct but complementary expertise of different laboratories to create opportunities for synergy and will make possible the coalescence of these interactions into formal collaborative | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| CHILDREN'S MEMORIAL HOSPITAL, THE | $100,483 | Grant | Trans-NIH Recovery Act Research Support: The overall purpose of the Administrative Supplement to my K 22 grant is to extend my research on regulatory pathways that promote prostate cancer bone metastasis and demonstrate a novel relationship between two highly conserved pathways in development an | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $90,417 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Hepatocyte transplantation (HT) could be an alternative to orthotopic liver transplantation in the treatment of both inherited and acquired liver diseases. However, benefits of this procedure are currently limited by ( | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| RESEARCH FOUNDATION FOR MENTAL HYGIENE INC | $79,796 | Grant | Trans-NIH Recovery Act Research Support: This supplement is intended to support a significant expansion of the parent grant's scope and research protocol. The project is designed to better allow investigators to assess patterns of drug use, effects of potential adverse behavioral, social and he | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| UNIVERSITY OF MISSOURI SYSTEM | $678,643 | Grant | Trans-NIH Recovery Act Research Support: Cocaine abuse is a public health problem reaching our young adults and even unborn children. Cocaine can be very addictive, eliciting a number of physiological and neuropsychiatric effects. Published reports indicate that sigma1 receptor antagonists can r | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $788,333 | Grant | Trans-NIH Recovery Act Research Support: The long term goal of this project is to understand the molecular mechanisms of alcohol's actions. Due to its small size and lack of chemical features, alcohol is often considered to be a relatively non-specific drug. Many cellular factors have been ident | Health and Human Services, Department of / National Institutes of Health | 9/10/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $1,248,442 | Grant | Trans-NIH Recovery Act Research Support: From a combination of genetic analyses and RNAi screening, we have discovered hundreds of gene inactivations and mutations that regulate C. elegans lifespan. We propose to GFP tag these genes to discern their molecular identity as well as to delineate fro | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $747,077 | Grant | Trans-NIH Recovery Act Research Support: Friedreich's ataxia (FRDA) is an inherited mitochondrial neurodegenerative and demyelinating disease that affects thousands in the US, and several thousands more worldwide. Friedreich's ataxia results from a deficiency in the expression of the mitochondri | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| UTAH STATE UNIVERSITY | $2,993,593 | Grant | Trans-NIH Recovery Act Research Support: Progression of Dementia: A Population Study (R01AG21136) The Cache County Dementia Progression Study (DPS; R01AG21136) has been funded from NIA since 2002, and with the current ARRA award, will be extended through 2012, a one-year no cost extension. This | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| PENNSYLVANIA STATE UNIVERSITY, THE | $772,304 | Grant | Trans-NIH Recovery Act Research Support: Hepatitis B virus (HBV) is a major cause of chronic viral hepatitis that increases dramatically the risk of liver cancer and other end-stage liver diseases such as cirrhosis. HBV belongs to the Hepadnaviridae, a family of para-retroviruses that have a sma | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| ST. JUDE CHILDREN'S RESEARCH HOSPITAL | $840,000 | Grant | Trans-NIH Recovery Act Research Support: This is a renewal application to study the underlying mechanisms of activation-induced cell death (AICD) in T cells, one of the primary mechanisms of clonal deletion and therefore central to our understanding of the immune system. Here, we define AICD as | Health and Human Services, Department of / National Institutes of Health | 7/23/2009 |
| TEXAS A&M UNIVERSITY SYSTEM,THE | $659,250 | Grant | Trans-NIH Recovery Act Research Support: The high incidence of tuberculosis worldwide is due to a number of factors, including the high frequency of co-infection in AIDS patients, continued emergence of drug resistance, incomplete sterilizing activity of therapeutic regimen and the ability of M. | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF CHICAGO, THE | $633,792 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of our research is to investigate how the intracellular signaling circuitry is wired in response to specific extracellular stimuli, thereby identifying potential therapeutic targets for prevention and treatment of human diseases. In thi | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| DUKE UNIVERSITY | $674,806 | Grant | Trans-NIH Recovery Act Research Support: Important concerns have been raised about the ethics of phase 1 clinical trials in oncology. In previous research, many patients have reported high expectations of personal clinical benefit from phase 1 trials. In the project leading to this application ( | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $596,014 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): SAG (Sensitive to Apoptosis Gene), also known as RBX2/ROC2, or RNF7 (RING finger protein 7), is a stress-responsive component of SCF (Skp1, Cullins, F-box proteins) E3 ubiquitin ligase. Our previous work has shown that | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $554,750 | Grant | Trans-NIH Recovery Act Research Support: This project investigates 'impulsivity' as a predisposing factor for drug abuse. Drug abuse researchers have extensively studied 'reward-related' factors that facilitate drug-seeking behaviors, including both unconditioned and conditioned positive affecti | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| VIRGINIA COMMONWEALTH UNIVERSITY | $595,689 | Grant | Trans-NIH Recovery Act Research Support: The proposed studies will investigate mechanisms of regulation of cannabinoid receptors in brain by 9-tetrahydrocannabinol, the active ingredient in marijuana and cannabinoid-based therapeutics. These studies will elucidate cellular and molecular mechanis | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| BETH ISRAEL DEACONESS MEDICAL CENTER INC | $656,695 | Grant | Trans-NIH Recovery Act Research Support: Muscle wasting is a debilitating feature of many disease states including diabetes and renal failure. We initially identified atrogin-1 as a gene that is strongly induced during muscle wasting in various animal models of disease. Its absence protects musc | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH | $912,641 | Grant | Trans-NIH Recovery Act Research Support: 4-Hydroxynonenal (4-HNE), a stable end-product of lipid peroxidation (LPO) can cause toxicity through apoptosis and necrosis. During current funded years, we have established that GSTA4-4 and RLIP76 are the major determinants of the intracellular concentr | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| TEXAS A&M UNIVERSITY SYSTEM,THE | $536,992 | Grant | Trans-NIH Recovery Act Research Support: Protein targeting and transport across lipid bilayers is a fundamental energy-requiring process in all organisms. Up to approximately half of the proteins in an organism's proteome are inserted into or transported across membranes by protein translocation | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $641,174 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of this study is to understand the biological function of protein modification by the ubiquitin like protein ISG15. In recent years our knowledge of protein ubiquitination (ubiquitylation) has expanded rapidly and as a consequence prote | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $701,250 | Grant | Trans-NIH Recovery Act Research Support: The long-term objective of this project is to determine in molecular detail the energetic-structure-function relationship in plasma apolipoproteins and lipoproteins and thereby provide an insight into molecular mechanisms of lipoprotein action in the deve | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $594,768 | Grant | Trans-NIH Recovery Act Research Support: Nitric oxide signaling is critical to several physiological functions, and dysfunction in this signaling cascade is implicated in multiple diseases such as erectile dysfunction, heart disease, neurodegeneration, stroke, hypertension, and gastrointestinal | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $585,949 | Grant | Trans-NIH Recovery Act Research Support: Linear directed movement, such as seen in muscle contraction, cell motility, and intracellular trafficking, is one of the fundamental characteristics of life and is mediated primarily by the myosin, kinesin, and dynein superfamilies of motor proteins. The | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| ROCKEFELLER UNIVERSITY FACULTY AND STUDENTS CLUB INC, THE | $980,576 | Grant | Trans-NIH Recovery Act Research Support: The ultimate objective of my laboratory is to decipher the molecular basis of neural/epidermal induction and patterning in the vertebrate embryo. Our previous work has shown that one of the earliest steps in the determination of neural fate requires inhib | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $784,083 | Grant | Trans-NIH Recovery Act Research Support: The goal of this work is to establish a scientific basis for treating crouch gait, one of the most common movement abnormalities among children with cerebral palsy. Crouch gait is characterized by persistent flexion of the knee. It is an inefficient means | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $1,513,760 | Grant | Trans-NIH Recovery Act Research Support: Autism is a developmental disorder and affected individuals have alterations in brain function disrupting their ability to perform particular motor and cognitive tasks. The main long term objective of this project is to determine in one major affected bra | Health and Human Services, Department of / National Institutes of Health | 8/27/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $959,147 | Grant | Trans-NIH Recovery Act Research Support: The long-term objective of this research is to define the mechanisms occurring within the primate corpus luteum (CL) that are critical for its development, function, and regression. Evidence obtained from nonprimate species indicates that prostaglandins r | Health and Human Services, Department of / National Institutes of Health | 7/28/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $893,322 | Grant | Trans-NIH Recovery Act Research Support: This application describes a project that aims to answer the question, do some parts of the human genome function by virtue of their structure, and not directly by their nucleotide sequence? To address this question a structural map of the 30 Mb of the EN | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| HAMNER INSTITUTES, THE | $225,000 | Grant | Trans-NIH Recovery Act Research Support: The support from this award will allow continued investigation of fat cell metabolism in response to adrenaline and promote understanding of new intracellular pathways that may be able to be targeted for managment of obestiy and metabolic disease | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF CINCINNATI | $349,484 | Grant | Trans-NIH Recovery Act Research Support: Manganese (Mn) is an essential element, yet is neurotoxic in excess. Despite the fact that infants and young children may be at greater risk for Mn neurotoxicity than adults, very few studies have evaluated the effect of chronic Mn exposure on child devel | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| THE VANDERBILT UNIVERSITY | $45,806 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement request seeks to provide employment for a highly skilled Ph.D. level scientist who is being laid off from another laboratory due to budget constraints related to the economic downturn. In addition we request support for an G | Health and Human Services, Department of / National Institutes of Health | 7/11/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $149,341 | Grant | Trans-NIH Recovery Act Research Support: Supplemental funds are requested to develop improved apparatus and to hire a post doctoral fellow. These improved apparatus will enhance the quality of the data we collect to achieve the specific aims of the fundedparent grant, and hiring an additional po | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| NEW YORK UNIVERSITY | $226,196 | Grant | Trans-NIH Recovery Act Research Support: This supplement increases project support, both for a postdoctoral scientist and equipment, to accelerate the pace of the research. Patients with Parkinson's disease and other basal ganglia disorders are crippled by dysfunctional, or inefficient, moveme | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| THE JACKSON LABORATORY | $242,680 | Grant | Trans-NIH Recovery Act Research Support: This supplement will enhance studies described in the parent grant in order to accelerate the discovery process and our understanding of the function of Mfrp, C1qtnf5 and Crb1. Each of these genes when mutated leads to ocular disease in humans but their f | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| NORTHWESTERN UNIVERSITY | $152,332 | Grant | Trans-NIH Recovery Act Research Support: This study addresses the relationship between the specialized structure of the mammalian cone photoreceptor synapse and signaling in postsynaptic bipolar cell pathways that are critical for visual perception. Cone photoreceptors mediate vision under condi | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| SCHEPENS EYE RESEARCH INSTITUTE, INC., THE | $450,441 | Grant | Trans-NIH Recovery Act Research Support: Central vision loss is the leading vision impairment, affecting millions of people worldwide. Curative treatment options for those eye diseases are currently limited, optical or electronic magnifiers are currently the most commonly used visual aids for r | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| OAKLAND UNIVERSITY | $21,161 | Grant | Trans-NIH Recovery Act Research Support: The long-term objective of this proposal is to define the molecular scaffolding that underlies the dynamic architecture of vertebrate rod and cone photoreceptor outer segments (OSs). Retinal photoreceptors provide important paradigms for modern biology, i | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $301,555 | Grant | Trans-NIH Recovery Act Research Support: The Supplement was awarded to investigate the hypotheses that alleles of the ABCA4 gene modify the onset and course of age-related macular degenration (AMD) and conversely, that alleles in 4 major AMD-associated loci modify the course of Stargardt disease | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| CEDARS-SINAI MEDICAL CENTER | $591,999 | Grant | Trans-NIH Recovery Act Research Support: Diabetic retinopathy (DR) is the leading cause of blindness in people aged 20-74 years in the United States. Although retinopathy is more common in type 1 diabetes, the majority of new cases are due to type 2 diabetes (T2DM). The socioeconomic cost of DR | Health and Human Services, Department of / National Institutes of Health | 9/02/2009 |
| CHILDREN'S MEMORIAL HOSPITAL, THE | $127,409 | Grant | Trans-NIH Recovery Act Research Support: Our long-term goal is to elucidate the roles of a novel protein C53 in regulation of cell cycle progression and DNA damage response, and to explore potential utilization of this novel protein as a novel therapeutic approach. Regulation of cell cycle and | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| UNIVERSITY OF MASSACHUSETTS | $423,847 | Grant | Trans-NIH Recovery Act Research Support: The recently recognized subset of Th17 effector T cells informs our understanding of both normal cellular immune responses as well as mechanisms leading to several autoimmune diseases. For example, we now know that Th17 cells are responsible for the clear | Health and Human Services, Department of / National Institutes of Health | 5/04/2009 |
| UNIVERSITY OF MASSACHUSETTS | $806,750 | Grant | Trans-NIH Recovery Act Research Support: Pituitary adenomas are among the most prevalent of human tumors, affecting over 15% of the population in the United States. However, it is not yet known what regulates the division of endocrine cells in adults. Hedgehog (Hh)/Gli and Fgf-mediated cell-cel | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| UNIVERSITY OF MASSACHUSETTS | $819,266 | Grant | Trans-NIH Recovery Act Research Support: 'The long-term goal of this project is to apply molecular approaches to characterize and manipulate Taxus metabolism for production of the anti-cancer agent paclitaxel (Taxol''), a potent anti-cancer agent approved by the FDA for the treatment of breast, | Health and Human Services, Department of / National Institutes of Health | 9/08/2009 |
| UNIVERSITY OF PITTSBURGH THE | $537,076 | Grant | Trans-NIH Recovery Act Research Support: Cancer of the colon and rectum (colorectal cancer, CRC) is the third leading site of cancer in the United States and the most common form of gastrointestinal malignancy. CRC accounts for approximately 150,000 new cases annually, and 6,000 of these are tre | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| LOUISIANA STATE UNIVERSITY SYSTEM | $396,771 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): This proposal addresses the need for the development of efficient boron delivery agents for application in a new treatment modality for intractable brain tumors and other malignancies, boron neutron capture therapy (BN | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| VIRGINIA COMMONWEALTH UNIVERSITY | $100,335 | Grant | Trans-NIH Recovery Act Research Support: The main objectives of the administrative supplement are to further establish the mechanisms by which colonic inflammation results in down-regulation of smooth muscle calcium channels. Part of the long-term goals of the parent grant are to define the cell | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| KAISER FOUNDATION HOSPITALS | $316,000 | Grant | Trans-NIH Recovery Act Research Support: The Study of Osteoporotic Fractures (SOF) was competitively renewed to study why some women achieve and maintain high cognitive and physical function, and low risk of falls and fractures in the 9th and 10th decade of life. The SOF Coordinating Center was | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| ROCKEFELLER UNIVERSITY FACULTY AND STUDENTS CLUB INC, THE | $845,000 | Grant | Trans-NIH Recovery Act Research Support: Class switch recombination (CSR) is an important mechanism for diversification of the humoral immune response. It is initiated by activation induced cytidine deaminase (AID), an enzyme that converts cytidine to uracyl in single stranded DNA thereby creati | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| DUKE UNIVERSITY | $1,563,767 | Grant | Trans-NIH Recovery Act Research Support: Few studies have examined the relationship with gene on the DNA repair and apoptosis pathways. Our preliminary data support associations with several single nucleotide polymorphism in genes in these pathways but a larger sample size is needed to confirm t | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| HENRY M JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY M | $672,410 | Grant | Trans-NIH Recovery Act Research Support: Gastric Carcinoma is the second leading cause of cancer death worldwide. Because survival at 5 year is very low,there is a need for a better understanding of the pathogenesis of the disease. These studies will permit a prospective analysis of the histolog | Health and Human Services, Department of / National Institutes of Health | 6/09/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $518,590 | Grant | Trans-NIH Recovery Act Research Support: The ability to understand and harness the combined potential of early activated T cell generation and robust circulating DC induction could serve to synergistically augment in the generation of an effective anti-tumor response in vivo. The two year ARRA f | Health and Human Services, Department of / National Institutes of Health | 6/19/2009 |
| UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE | $3,367,155 | Grant | Trans-NIH Recovery Act Research Support: This is the second competitive renewal for this Program Project Grant. During the first two cycles, the focus has been on the molecular and cellular pathways that regulate the balance of Th1 and Th2 cytokine patterns. This Program Project combines the ex | Health and Human Services, Department of / National Institutes of Health | 7/23/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $2,708,532 | Grant | Trans-NIH Recovery Act Research Support: Proper immune responses are necessary to control pathogenic infections. It is equally important to limit immunological responses properly so that they do not cause chronic inflammation or autoimmune diseases. Thus, understanding molecular and cellular p | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| OKLAHOMA MEDICAL RESEARCH FOUNDATION | $563,500 | Grant | Trans-NIH Recovery Act Research Support: RNA-binding nuclear antigens are a major class of autoantigen targeted in systemic autoimmune diseases, including systemic lupus erythematosus (SLE) and Sj+?gren's syndrome (SS). The mechanisms that normally mediate immunologic tolerance to RNA-binding nu | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| NEW YORK MEDICAL COLLEGE | $765,500 | Grant | Trans-NIH Recovery Act Research Support: The ability to extract biologically relevant information from the genome of Borrelia burgdorteri, the cause of Lyme disease, continues to be hampered by the lack of genetic tools to identify the biological functions of its many genes of unknown function. | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $760,358 | Grant | Trans-NIH Recovery Act Research Support: Extracellular secretion and targeted delivery by the type II secretion (T2S) system is considered a major virulence mechanism in gram negative pathogens, as many of the proteins secreted via the T2S pathway constitute important virulence factors, includin | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| UNIVERSITY OF CONNECTICUT | $605,724 | Grant | Trans-NIH Recovery Act Research Support: The double-stranded (ds) RNA-activated protein kinase, PKR, is one of several proteins induced by interferon and plays a pivotal role in the cellular antiviral response. PKR has also been implicated in other cellular processes including transformation, di | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| BETH ISRAEL DEACONESS MEDICAL CENTER INC | $606,739 | Grant | Trans-NIH Recovery Act Research Support: Xenotransplantation may be clinically feasible once the molecular barriers between species and mechanisms of graft loss or rejection are better understood. Xenograft survival would have to be also achieved without compromising the recipient to the extent | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $710,982 | Grant | Trans-NIH Recovery Act Research Support: Endochondral bone formation is a complex process in which mesenchymal cells initially differentiate into chondrocytes, giving rise to cartilage elements that form templates for most of the skeleton. This process is regulated by several important hormones | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $750,000 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of this proposal is to understand the fundamental biophysical properties that link the human MutS homologues (MSH) and MutL homologues (MLH/PMS) to their essential role(s) in signaling mismatch repair (MMR) and/or damage-induced apoptos | Health and Human Services, Department of / National Institutes of Health | 6/03/2009 |
| THE VANDERBILT UNIVERSITY | $798,101 | Grant | Trans-NIH Recovery Act Research Support: The E2C2 has previously expressed its interest in validating the significant findings of our study (see attached support letter). Herein, we request additional funds to support the expanded validation component. Specifically, the supplemental funds will | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $975,209 | Grant | Trans-NIH Recovery Act Research Support: The lens of the eye is a complex organ that, with the cornea, focuses an image on the retina. Lens cells have glucose transporters, chloride channels, sodium and potassium channels, gap junctions, and many other standard transport proteins in common with | Health and Human Services, Department of / National Institutes of Health | 6/03/2009 |
| NORTH CAROLINA STATE UNIVERSITY | $13,934 | Grant | Trans-NIH Recovery Act Research Support: Some 30-40 million people are living with Human immunodeficiency virus, HIV. Other retroviruses account for many more infections, and emerging infectious diseases are on the rise. Unfortunately, antiretroviral resistance develops in the presence of the se | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $614,279 | Grant | Trans-NIH Recovery Act Research Support: The H+-transporting F1Fo ATP synthases of oxidative phosphorylation in mitochondria and bacteria are very similar. Rotation of subunit gamma within the core of the alpha3beta3 hexamer of F1 drives ATP synthesis by a mechanically driven change in binding a | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE | $734,738 | Grant | Trans-NIH Recovery Act Research Support: Protein-DNA selectivity is a central event in many biological processes, ranging from transcription and replication to restriction and modification. Because of the excess of non-specific sequences in a cell the initial encounter between a protein and DNA | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| THOMAS JEFFERSON UNIVERSITY | $633,450 | Grant | Trans-NIH Recovery Act Research Support: Sensitization of IP3R/RyR-mediated Ca2+ release may cause a shift from the physiological to the pathophysiological range of mitochondrial calcium signaling and that a variety of mutations associated with human skeletal (malignant hyperthermia) and cardiac | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $759,647 | Grant | Trans-NIH Recovery Act Research Support: The diversity of all living organisms is encoded within their DNA, where it is stably maintained through DNA replication, and then retrieved through transcription into RNA and translation into proteins. Thus. the di....ersity of life is limited by the fou | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $643,842 | Grant | Trans-NIH Recovery Act Research Support: The continuing development of efficient high-performance liquid chromatography (HPLC) protocols is critical for all areas of biomedical science and biotechnology. The major areas under investigation in our laboratory are: (1) development of novel and impr | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| UNIVERSITY OF ROCHESTER | $673,524 | Grant | Trans-NIH Recovery Act Research Support: Our goal is to sketch out the broad principles by which these ncRNAs acquire activity from structure, which will provide a foundation to develop new therapeutic agents and the next generation of antibiotics. Non-protein-coding (nc)RNAs are undergoing | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $55,366 | Grant | Trans-NIH Recovery Act Research Support: For student participation in a funded project supported by the Center grant to determine environmental factor interact with genetic risk factors in progression of Parkinson's disease. ARRA Summer Supplement of funds. | Health and Human Services, Department of / National Institutes of Health | 6/17/2009 |
| THOMAS JEFFERSON UNIVERSITY | $956,943 | Grant | Trans-NIH Recovery Act Research Support: This New Faculty Supplement provides funding for a new physician-scientist recruit who will expand on her program related to stem cells underlying hepato-billiary tumorigenesis. In this context, the recruit will represent a key new faculty member in our | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| YALE UNIVERSITY | $245,500 | Grant | Trans-NIH Recovery Act Research Support: An administrative supplement is requested for the George M. OBrien Kidney Center at Yale. The principal goal of the Yale Center is to provide renal investigators both at Yale and across the country with access to highly specialized services not otherwise | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $57,693 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this Administrative Supplement which is affiliated with the Center for Vulnerable Populations Research investigators (n=5) is to support summer research experiences for 7 undergraduate nursing students and 2 high school students who are pre | Health and Human Services, Department of / National Institutes of Health | 6/17/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $307,756 | Grant | Trans-NIH Recovery Act Research Support: Factors in FTD and ADG? (PI: Dr. Geschwind) proposes to accelerate research into the genetics of Frontotemporal lobar degeneration and AlzheimerG??s Disease by expanding the scope of the parent application introducing novel cutting-edge methods. Recent te | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY | $535,857 | Grant | Trans-NIH Recovery Act Research Support: Rationale: We have developed urinary cell mRNA profiling protocols and demonstrated that measurement of urinary cell mRNAs offers a noninvasive means of diagnosing acute rejection. We have reported, for the first time, that: (a) urinary cell levels of mRN | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE | $668,500 | Grant | Trans-NIH Recovery Act Research Support: Heparan sulfate plays essential roles in development of various tissues. To understand how heparan sulfate functions during skeletal development is of a great clinical importance. Hereditary multiple exostoses (HME) is one of the most common skeletal dysp | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| YALE UNIVERSITY | $312,953 | Grant | Trans-NIH Recovery Act Research Support: Metastasis is the major cause of mortality for cancer patients. However, the genetic basis for tumor progression and metastasis is largely unknown. It has been difficult to systematically dissect the mechanisms underlying these two disease processes in pa | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| YALE UNIVERSITY | $287,970 | Grant | Trans-NIH Recovery Act Research Support: The ability of retroviruses to efficiently manipulate cell-cell contacts for the purpose of spreading critically contributes to the progression to retrovirally induced diseases such as leukemia and AIDS. Our grant 2R01CA098727 is devoted to the determinat | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $126,713 | Grant | Trans-NIH Recovery Act Research Support: Therapeutic proteins provide unique and critical treatments for many human diseases and conditions However, if a protein product cannot be stabilized adequately, its benefit to human health will never be realized. Proteins are highly susceptible to the fo | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| RENSSELAER POLYTECHNIC INSTITUTE | $231,234 | Grant | Trans-NIH Recovery Act Research Support: Successful completion of this project will provide a new and powerful tool for quantitatively linking telltale structural properties of tissues (e.g., cellular distribution, morphology, contact) with specific disease states and fundamental behaviors of th | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $148,984 | Grant | Trans-NIH Recovery Act Research Support: To create algorithmic tools that aid basic and clinical neuroscientists in the analysis of variability in anatomical structures at different scales. The overall aim is to integrate 3D Slicer application and ITK software library with the statistical shape | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $216,466 | Grant | Trans-NIH Recovery Act Research Support: This project is in response to the Notice Number (NOT-OD-09-056) entitled ?NIH Announces the Availability of Recovery Act Funds for Administrative Supplements.? Specifically, we seek support to accelerate one arm of our parent grant R01 EB3028005 entitled | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $279,427 | Grant | Trans-NIH Recovery Act Research Support: The parent award aims to dramatically improve the spatial resolution of breast MRI though improved coil hardware and MRI acquisition methods. The improved spatial resolution will allow more accurate and earlier diagnosis of breast cancer. The purpose of | Health and Human Services, Department of / National Institutes of Health | 7/30/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $143,528 | Grant | Trans-NIH Recovery Act Research Support: The overarching goal of this project has been to determine the molecular mechanisms by which environmental chemicals impair the development of the mammalian immune system. The central hypothesis is that the developing B cell compartment is exquisitely se | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| UNIVERSITY OF CINCINNATI | $49,711 | Grant | Trans-NIH Recovery Act Research Support: This competing renewal application aims at investigating the hypothesis that exposure of human melanocytes to ultraviolet radiation (UV) and/or the physiological agonist 1-melanocyte stimulating hormone (1-MSH) or antagonist agouti signaling protein (ASIP | Health and Human Services, Department of / National Institutes of Health | 6/17/2009 |
| TEXAS A & M RESEARCH FOUNDATION | $131,963 | Grant | Trans-NIH Recovery Act Research Support: Exposure to environmental toxicants such as dioxin and benzo-a-pyrene (e .g.: from cigarette smoke) has severe adverse effects on maternal and fetal health. Placental stem cells which give rise to placenta are critical for the developing fetus. The effe | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| UNIVERSITY OF LOUISVILLE | $9,765 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the supplement is to hire an undergraduate student to assist with the creation and analyses of the mutant APC11 proteins. Participation in the project will provide the undergraduate student with a meaningful research experience. | Health and Human Services, Department of / National Institutes of Health | 7/11/2009 |
| UNIVERSITY OF PITTSBURGH THE | $189,375 | Grant | Trans-NIH Recovery Act Research Support: The coat protein complex II (COPII) mediates the sorting and export of cargo proteins from the endoplasmic reticulum (ER). We combine well-defined in vitro experimental systems that reconstitute COPII activities on ER membranes and liposomes, with cellula | Health and Human Services, Department of / National Institutes of Health | 8/18/2009 |
| UNIVERSITY OF CONNECTICUT | $0 | Grant | Trans-NIH Recovery Act Research Support: Work involves searching for the methods of healing or repairing of the heart already subjected to ischemia/reperfusion. Results found that ischemic myocardium initially attempts to protect itself by a process known as autophagy. Our preliminary studies do | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $987,722 | Grant | Trans-NIH Recovery Act Research Support: The peripheral chemoreceptors (carotid bodies) detect changes in blood oxygen and / or pH whereas central chemoreceptors detect changes in brain extracellular fluid pH. When activated, these receptors produce a large spectrum of effects that include the s | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $1,188,905 | Grant | Trans-NIH Recovery Act Research Support: The study of adaptation mechanisms in structure and function of blood vessels in response to physical stress is important in human health and disease. The general objective of this proposal is to elucidate how a chronic increase in stretch mediated by inc | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| THE UNIVERSITY OF SOUTH DAKOTA | $646,995 | Grant | Trans-NIH Recovery Act Research Support: Title: Androgens raise venous and arterial adrenergic tone. Cardiovascular disease is the leading cause of death for both men and women in the U.S. Essential hypertension afflicts 20-30% of the U.S. population and is a major risk factor for other diseas | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| UNIVERSITY OF UTAH, THE | $874,471 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Our research proposal-Reductive Stress in the Pathogenesis of R120GCryAB Cardiomyopathy-is directly responsive to the new NHLBI Strategic Plan, which urges efforts to improve our understanding of the molecular and phys | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $831,106 | Grant | Trans-NIH Recovery Act Research Support: Recovery Act funds have been awarded for the study of ?Angiogenesis in the Lung?. This award continues to partially supports two full time faculty members. The work is focused on determining mechanisms of neovascularization in the lung. Excessive systemic | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER | $1,051,415 | Grant | Trans-NIH Recovery Act Research Support: The primary long-term objective of this study is to determine the epidemiology and genetics of non-alcoholic fatty liver (NAFLD). The study has three primary specific aims: 1) Determine the prevalence and clinical correlates of fatty liver in the Multi-E | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $765,000 | Grant | Trans-NIH Recovery Act Research Support: Adult mesenchymal stem cells are fascinating cells that can be isolated and expanded from human bone marrow or fat, and returned to a patient to revascularize and repair tissues following injury such as heart attack or peripheral vascular disease. They do | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $1,491,183 | Grant | Trans-NIH Recovery Act Research Support: When computerized provider order entry (CPOE) is coupled with real-time computer-based decision support (CDS), medical errors decrease and costs can drop because clinicians can be alerted to potential errors or guided to select lower cost medications and | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| BRANDEIS UNIVERSITY | $933,452 | Grant | Trans-NIH Recovery Act Research Support: CaMKII is the most abundant kinase in neurons and is highly concentrated at synapses. The kinase has switch-like on/off properties that are activated during LTP induction. Mutations that interfere with this switching produce strong deficits in LTP and mem | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $687,916 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of these experiments is to resolve the structural and functional organization of the neural networks responsible for controlling neuroendocrine CRH neurons in the paraventricular nucleus of the hypothalamus (PVH). The PVH is the key con | Health and Human Services, Department of / National Institutes of Health | 7/24/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE | $839,690 | Grant | Trans-NIH Recovery Act Research Support: A striking feature of the developing central nervous system is the absolute precision with which synaptic circuitry first forms. At the same time, many synapses are eliminated, or rearranged and final synapse location and number is influenced by activity | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| UNIVERSITY OF PITTSBURGH THE | $757,500 | Grant | Trans-NIH Recovery Act Research Support: It is now established that at least three unique cell death pathways contribute to neuronal death after traumatic brain injury (TBI) in experimental models and in humans. These include the necrotic, caspase-dependent apoptotic, and caspase-independent apo | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $1,252,935 | Grant | Trans-NIH Recovery Act Research Support: Since presenting our findings that disease-reversal could be observed in a conditional mouse model of Huntington's Disease, we have sought the key cellular events that led to this observation. Our current working hypothesis is that the elimination of accu | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| EVERGREEN STATE COLLEGE | $193,277 | Grant | Trans-NIH Recovery Act Research Support: The award supports the research in rational development of phage cocktails targeting E coli O157:H7. Recent E coli O157:H7 outbreaks have eroded consumer confidence and again made food safety a major issue in the medical and agricultural arena. In recen | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| FORDHAM UNIVERSITY | $264,750 | Grant | Trans-NIH Recovery Act Research Support: The long-term objective of this research is to develop an understanding of the underlying cellular events and mechanisms involved in mutations in ion channel disorders. Mutations in Kv1.1 potassium (K+) channel coding regions cause the autosomal dominant | Health and Human Services, Department of / National Institutes of Health | 5/15/2009 |
| EAST CAROLINA UNIVERSITY | $334,163 | Grant | Trans-NIH Recovery Act Research Support: Indigenous intestinal microflora of humans has a commensal association with its host which influences many of the host?s physiological, nutritional, developmental, and immunological activities. This mutualistic relationship is maintained by physical barri | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $385,000 | Grant | Trans-NIH Recovery Act Research Support: STAT4 IMMUNOBIOLOGY T cell mediated inflammation is required for immunity to many pathogens but also is a critical component of autoimmune disease. These studies focus on a transcription factor, Stat4, which controls T cell function. The experiments descr | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| UNIVERSITY OF ROCHESTER | $384,595 | Grant | Trans-NIH Recovery Act Research Support: Proper B cell tolerance ensures effective censoring of autoreactive B cells thereby avoiding their participation in effector pathogenic response and preventing autoimmune diseases. The breakdown of B cell tolerance is at the core Systemic Lupus Erythemat | Health and Human Services, Department of / National Institutes of Health | 7/23/2009 |
| MAYO CLINIC | $720,202 | Grant | Trans-NIH Recovery Act Research Support: The vast majority of HIV-1 infections occur at mucosal surfaces in the body. There is therefore an immediate need for potent HIV vaccines that can provide barrier protection at mucosal surfaces. While there is this need,most HIV vaccines have been develop | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $182,882 | Grant | Trans-NIH Recovery Act Research Support: Severe osteopenia is a prevalent complication of anorexia nervosa (AN), affecting over half of all women with this disease. Loss of bone mass occurs frequently and is often permanent. Reduction of bone mineral density (BMD) by at least 1.0 SD at one or mo | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $395,660 | Grant | Trans-NIH Recovery Act Research Support: This is a revised resubmission of a competitive renewal application for a Rheumatology Training Grant that was first funded in 1976, and that aims to prepare qualified individuals for careers as independent investigators in areas of basic and clinical res | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF ILLINOIS | $800,000 | Grant | Trans-NIH Recovery Act Research Support: The thrust of the present project is drug discovery based at the University of Illinois at Chicago (UIC), with partner institution at the Vietnamese Academy of Science and Technology, Hanoi (Institute of Chemistry), and an industrial partner based in Prin | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF NEBRASKA | $54,000 | Grant | Trans-NIH Recovery Act Research Support: Multidrug resistance is a major obstacle to curing cancer because cancer cells become resistant to diverse and unrelated therapeutic compounds. A mechanism for multidrug resistance is the active extrusion of chemotherapeutic drugs from cancer cells by ABC | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| YALE UNIVERSITY | $52,531 | Grant | Trans-NIH Recovery Act Research Support: Chronic liver disease is the 10th leading cause of death in the USA,but liver transplantation is available to only a select few patients. Therefore, non-surgical alternatives are urgently needed. Surprisingly, adult bone marrow contains cells capable of e | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $54,000 | Grant | Trans-NIH Recovery Act Research Support: Latent Class Analysis in the GAIN data to address Symptom Dimensions in Psychosis This administrative supplement to the K-award K08 MH074057 is requested to accelerate the pace of the proposed research and to improve the infrastructure of the research gro | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $12,914 | Grant | Trans-NIH Recovery Act Research Support: There is an urgent need to understand the biological and functional changes associated with brain aging, particularly when considering that age is the most potent risk factor for developing Alzheimer's disease (AD). Myelination and speed of mental process | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| YALE UNIVERSITY | $53,229 | Grant | Trans-NIH Recovery Act Research Support: The objective of the primary research protocol presented in the PI's parent K-24 renewal application (Complications of Cirrhosis) aimed at comparing the efficacy of a combination of vasoconstrictors (octreotide + midodrine) vs. standard intravenous albumi | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| YALE UNIVERSITY | $264,299 | Grant | Trans-NIH Recovery Act Research Support: The goal of these studies is to understand the properties of naturally occurring immune responses against cancer stem cells in people without cancer. Harnessing such responses may be important for prevention of cancer, such as myeloma. | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| THE CHILDRENS HOSPITAL LOS ANGELES | $189,054 | Grant | Trans-NIH Recovery Act Research Support: The scientific purpose of this adminitrative supplement is to increase the pace of scientific discovery for our currently funded parent grantby advancing biomaker analysis and targeted tumor treatment strategies associated with Photodynamic Therapy (PDT). | Health and Human Services, Department of / National Institutes of Health | 9/08/2009 |
| BAYLOR COLLEGE OF MEDICINE | $291,311 | Grant | Trans-NIH Recovery Act Research Support: We will develop high resolution CGH arrays to detect mutations on mouse chromosome 11 . In our parent grant, we propose to assign function to a number of genes on mouse chromosome 11 | Health and Human Services, Department of / National Institutes of Health | 8/27/2009 |
| YALE UNIVERSITY | $62,266 | Grant | Trans-NIH Recovery Act Research Support: In this application we are requesting funds for 3 pieces of key equipment to achieve the goals of the specific Aim proposed in Treloar_5 R01 DC 007600-04_ACC 1) A Kodak imaging station to allow multimodal molecular imaging of gels blots and plates. Curren | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF TENNESSEE | $151,293 | Grant | Trans-NIH Recovery Act Research Support: Neurotrophins play crucial roles in innervation and development of taste buds. Brain-derived neurotrophic factor (BDNF), Neurotrophin-3 (NT-3) and Neurotrophin-4 (NT-4) are members of the neurotrophin family and have been shown to influence the lingual gu | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF KANSAS CENTER FOR RESEARCH, INC. | $174,060 | Grant | Trans-NIH Recovery Act Research Support: Most children transition from presymbolic (e.g., gestures and vocalizations) to symbolic (e.g., words) communication during the first year of life. This transition enables children to communicate more efficiently and leads to further developments in langu | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF KANSAS CENTER FOR RESEARCH, INC. | $296,171 | Grant | Trans-NIH Recovery Act Research Support: This program of investigation focuses on the genetics of Specific Language Impairment. We investigate longitudinal behavioral language phenotypes within a multi-gene developmental model involving a complex interaction of genetics, developmental brain chan | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| YALE UNIVERSITY | $61,235 | Grant | Trans-NIH Recovery Act Research Support: To assess whether blood-borne lactate, a potential alternative (non-glucose) monocarboxylic acid brain fuel, can support neuronal function during acute hypoglycemia in a rat model of type-1 diabetes (antecedent recurrent insulin-induced hypoglycemia). Rec | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF TENNESSEE | $49,903 | Grant | Trans-NIH Recovery Act Research Support: This supplement to grant number 01 DK 074565-01, A Cell Biological Approach to Lipid Absorption, is designed to speed the discovery of new information related to the control of dietary lipid absorption. As is well known, obesity is a current crisis of he | Health and Human Services, Department of / National Institutes of Health | 8/24/2009 |
| UNIVERSITY OF TENNESSEE | $71,755 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the this administrative supplement Notice NOT-OD-09-056 G?to provide researchers supplementary funds that can be used to accelerate the tempo of scientific research on active grants, with the ultimate goal of promoting job creation and econ | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $70,406 | Grant | Trans-NIH Recovery Act Research Support: Children with chronic/congenital diarrhea have defects in a variety of transporters and enzymes that have important but selective roles in nutrient and ion assimilation. Last year we identified the clinical phenotype and molecular basis of a novel human d | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF NEBRASKA | $188,363 | Grant | Trans-NIH Recovery Act Research Support: Coronary thrombosis on a ruptured coronary plaque is the main pathophysiologic event that leads to acute coronary syndromes (ACS). Clinical methods currently utilized to treat this are fibrinolytic agents or percutaneous coronary interventions, combined w | Health and Human Services, Department of / National Institutes of Health | 7/30/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $192,254 | Grant | Trans-NIH Recovery Act Research Support: This is a competitive supplement to our parent grant from the NIEHS Environmental toxin interactions with genetic risks for Parkinson's disease. We are interested in dissecting the interplay between pesticide exposure and excess cytoosolic dopamine (DA) | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $34,789 | Grant | Trans-NIH Recovery Act Research Support: 1. Cellular organization and relationship of SRIF and DA amacrine cells in the mammalian retina 2. Development of ON and OFF thy 1.2 YFP expressing mouse cone bipolar cells in vitro | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| YALE UNIVERSITY | $238,906 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of this project is to understand how ring canals contribute to cell function. Ring canals ubiquitous in developing germline cells in the animal kingdom, and are required for fertility. They form ring mitotic proliferation of germline st | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| THE HOSPITAL FOR SPECIAL SURGERY FUND INC | $297,500 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the experiments supported by this ARRA supplement was to identify an enzyme that has a critical role in the pathogenesis of Alzheimers Disease, the alpha secretase for the Amyloid Precusor Protein. Briefly, a proteolytic breakdown product | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| CASE WESTERN RESERVE UNIVERSITY | $354,752 | Grant | Trans-NIH Recovery Act Research Support: This grant is to study basic mechanisms of bacterial Ag processing with a primary focus on MHC-I cross processing. MTB is selected as a model organism that represents an excellent model for processing of intravacuolar pathogens in addition to its signific | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF NEBRASKA | $111,375 | Grant | Trans-NIH Recovery Act Research Support: The goals of this project are to begin the identification and study of nuclear proteins that associate with the transcription factor Sox2 during the reprogramming of somatic cells to a pluripotent stem cell state. Sox2 is a major focus of the PIG??s labo | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF NEBRASKA | $226,931 | Grant | Trans-NIH Recovery Act Research Support: The genes of Runx1 and its heterodimeric partner Cbf? are disrupted by chromosomal translocations, inversions and point mutations in over 30% of human leukemias. Ets1 is amplified and rearranged in leukemia and lymphoma, and elevated Ets1 expression has | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| EMORY UNIVERSITY | $410,820 | Grant | Trans-NIH Recovery Act Research Support: Shotgun Glycomics: Linking Glycan Structure and Function, 3R01GM085448-1 Shotgun Glycomics is a nanoscale approach that uses new bifunctional chemical derivatization to: 1) fluorescently tag all free glycans released from cell or tissue glycoconjugates; 2 | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF MASSACHUSETTS | $123,028 | Grant | Trans-NIH Recovery Act Research Support: This award was for supplemental funds ($75,000 direct costs) to support inclusion of research using iPS cells (induced pluripotent stem cells) to augment the goals of the parent R01 grant (GM085548). The overall goal of this funded project requires an inn | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| YALE UNIVERSITY | $35,583 | Grant | Trans-NIH Recovery Act Research Support: Implanting human cytotrophoblasts (CTBs) invade an underlying decidua comprised of decidual cells and such immune cells as macrophages (Mac) and dendritic cells (DCs). These specialized antigen-presenting cells (APCs) mediate innate immunity, subsequent a | Health and Human Services, Department of / National Institutes of Health | 6/02/2009 |
| SAN DIEGO STATE UNIVERSITY FOUNDATION | $157,724 | Grant | Trans-NIH Recovery Act Research Support: This project will focus on the question of whether Bax and Bid are recruited to mitochondria before or after the MPTP opens. We hypothesize that Bid recruitment follows MPTP opening because of exposure of cardiolipin. Accordingly, we will prepare recombin | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| UNIVERSITY OF LOUISVILLE | $235,546 | Grant | Trans-NIH Recovery Act Research Support: Description The first aim of this project is to identify the role of GSTP in preventing myocardial ischemia-reperfusion injury. To accomplish this aim we will subject wild-type (WT), GSTP-null and GSTP-transgenic (TG) mice to coronary ligation and reper | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF ARKANSAS SYSTEM | $145,012 | Grant | Trans-NIH Recovery Act Research Support: Fetal Magnetoencepahlography and Evoked Potentials - Although there has been a decrease in perinatal morbidity and mortality rates over the past four decades, hypoxia in the antepartum period, which leads to major motor and cognitive disabilities, continu | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| BAYLOR COLLEGE OF MEDICINE | $250,880 | Grant | Trans-NIH Recovery Act Research Support: Comparative analysis of ataxia transcriptomics; ABSTRCT - This administrative supplement application is to carry out a transcriptome analysis of the SCAs models simultaneously to the genetic modifier work proposed in the original application. Specifically | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| YALE UNIVERSITY | $89,300 | Grant | Trans-NIH Recovery Act Research Support: Human disorders caused by neuronal ion channel dysfunction are a major source of pain, suffering, and economic hardship. Their amelioration can be greatly facilitated by understanding the normal in vivo physiological functions served by the large number o | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $170,909 | Grant | Trans-NIH Recovery Act Research Support: The specific aims of the parent grant are to study the role of STAT3, an intracellular signal transducer of the Jak-STAT family in regulating specific aspects of reactive astrogliosis after injury in the central nervous system. The purpose of the administ | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| YALE UNIVERSITY | $84,298 | Grant | Trans-NIH Recovery Act Research Support: The goal of this project is to establish the zebrafish bipolar cells as a system for studying the molecules involved neurotransmitter release from ribbon-type retinal neurons. Zebrafish are an excellent vertebrate model for physiology and disease, conduci | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $249,480 | Grant | Trans-NIH Recovery Act Research Support: The project titled California Center for Population Research is to enhance research environment and administrative support for population scientists at UCLA affiliated with the California Center for Population Research. We will use the additional support | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| SAN DIEGO STATE UNIVERSITY FOUNDATION | $168,845 | Grant | Trans-NIH Recovery Act Research Support: This fund is an ARRA diversity administrative supplement to Parent Fund #54862C entitled, 'M-RISP at SDSU.' This supplemental funding will provide a two-year full-time research employment opportunity for a postdoctoral student. The candidate will gain va | Health and Human Services, Department of / National Institutes of Health | 7/21/2009 |
| UNIVERSITY OF NEBRASKA | $538,868 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this proposal is to discover gene-linked SNPs in rhesus macaques (Macaca mulatta) and to make these SNPs easily accessible to the non-human primate research community. We will focus on identifying SNPs associated with genes of research | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE | $474,750 | Grant | Trans-NIH Recovery Act Research Support: The main goal of the proposed research is to understand the architecture, dynamics, and function of complex assemblies involved in transcriptional activation of human immunodeficiency virus type-1 (HIV-1) gene expression. HIV-1 encodes a transcriptional | Health and Human Services, Department of / National Institutes of Health | 7/23/2009 |
| CALIFORNIA STATE UNIVERSITY AUXILIARY SERVICES, INC | $62,726 | Grant | Trans-NIH Recovery Act Research Support: The parent project of the requested supplement is designed to investigate the sunlight-induced degradation of polycyclic aromatic hydrocarbons (PAHs) in liquid solutions, found on the surface of airborne fine-particulate matter. Early-life exposure to PA | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| CALIFORNIA STATE UNIVERSITY AUXILIARY SERVICES, INC | $105,673 | Grant | Trans-NIH Recovery Act Research Support: Research Aims and Activities of the Parent Grant: Antifreeze proteins (AFPs) have been found in many organisms including fish and insects to allow them to survive at subfreezing temperatures. AFPs are characterized by their ability to depress the freezing | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $68,030 | Grant | Trans-NIH Recovery Act Research Support: Medical Imaging Informatics Training Program- Administrative Supplement to purchase equipment. The purpose of this administrative supplement is to request the restoration of several pre- and post-doctoral slots to the UCLA Medical Imaging Informatics trai | Health and Human Services, Department of / National Institutes of Health | 8/20/2009 |
| UNIVERSITY OF KANSAS CENTER FOR RESEARCH, INC. | $35,173 | Grant | Trans-NIH Recovery Act Research Support: The pathogenesis of Gram-negative septic shock, a leading cause of mortality in critically ill patients, is a consequence of the overwhelming innate immune response to endotoxins, or lipopolysaccharides (LPS), present on the surface of Gram-negative bacte | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $532,052 | Grant | Trans-NIH Recovery Act Research Support: Support for data management center personnel to input, quality check, and manage data from the phase 3 NIH Field Administration of Stroke Therapy-Magnesium Trial (FAST-MAG), a study testing a new prehospital treatment for acute stroke. | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| YALE UNIVERSITY | $213,972 | Grant | Trans-NIH Recovery Act Research Support: The Yale Center for Clinical Investigation (YCCI) is the administrative home for the CTSA at Yale University School of Medicine. This supplemental proposal will advance YCCI community outreach through collaboration with the NIH SEPA grant based at the Ya | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $316,416 | Grant | Trans-NIH Recovery Act Research Support: We have developed the quantitative PCR assay to measure HPV DNA in the blood samples of patients with HPV(+) tumors. The assay can detect plasma HPV DNA in approximately 75% of the patient at diagnosis. It's also useful for tracking treatment response. A | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $533,649 | Grant | Trans-NIH Recovery Act Research Support: Gamma-secretase inhibitors (GSIs), which block the presenilin-gamma secretase complex, inhibit the production of amyloidogenic A? beta peptides involved in the pathogenesis of Alzheimer?s disease and the activation of NOTCH receptors. Recent identificatio | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $19,158 | Grant | Trans-NIH Recovery Act Research Support: The objective of this project is to study the inhibition of colon carcinogenesis by green tea polyphenol and their combination with atorvastatin (ATST, trade name Lipitor). The specific aims of the parent grant are as follows: 1. Determine the inhibitory | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO | $96,822 | Grant | Trans-NIH Recovery Act Research Support: Microtubule stabilizing agents are important drugs used in the treatment of cancer. The focus of this project is a new class of plant-derived microtubule stabilizers, the taccalonolides. The taccalonolides have a unique mechanism of action. They are the f | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $358,757 | Grant | Trans-NIH Recovery Act Research Support: Among the numerous side effects of cancer treatments, neurotoxicity occurs frequently and represents a significant clinical problem. Whether treatment regimens involve anticancer drugs, ionizing radiation (IR), or both, these treatment strategies designed | Health and Human Services, Department of / National Institutes of Health | 9/10/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $273,821 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): With the support of the current funded R01, we have modified and optimized our nanovectors for tumor targeted delivery of siRNA/shRNA specific to Bcl-2 and Bcl-xL. We found unexpectedly that our nanovectors also target | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $137,591 | Grant | Trans-NIH Recovery Act Research Support: The zinc:finger transcriptional repressor Gfi-1 has a critical intrinsic role in maintaining the function of hematopoietic stem cells (HSCs) and also controls a variety of their progeny at distinct, later stages of hematopoietic differentiation. HSCs lack | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $391,469 | Grant | Trans-NIH Recovery Act Research Support: The identification of the activating ligands for Toll-like Receptors (TLR) and Tumor Necrosis Factor family Receptors (TNFR) have provided the first logical, hypothesis-based strategies to molecularly concoct multifactorial adjuvants to elicit potent cell | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $155,391 | Grant | Trans-NIH Recovery Act Research Support: This application represents a request for administrative supplements for the parent RO1CA124515, entitled Vascular Leukocytes influence the tumor microenvironment, for a 2-year period. In the original project we proposed to define the therapeutic value of | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $270,180 | Grant | Trans-NIH Recovery Act Research Support: Protein degradation by proteasomes plays an essential role in the proliferation of malignant cells. The proteasome inhibitor VELCADE (bortezomib, PS-341) is being used for the treatment of multiple myeloma and is in clinical trials for the treatment of ot | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF WASHINGTON | $83,575 | Grant | Trans-NIH Recovery Act Research Support: Parent R21 Grant: The American Academy of Pediatrics guidelines for intervention in patients with hyperbilirubinemia (total serum bilirubin concentration (TSB) modified by clinical factors) are based on sparse published clinical evidence and do not consid | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $159,268 | Grant | Trans-NIH Recovery Act Research Support: Cardiovascular disease remains the leading cause of death in the United States and vascular calcification and diabetes are both independent risk factors for incident cardiovascular disease. Fetuin-A is a hepatic secretory protein found in high concentrati | Health and Human Services, Department of / National Institutes of Health | 7/31/2009 |
| WORCESTER POLYTECHNIC INSTITUTE | $197,601 | Grant | Trans-NIH Recovery Act Research Support: Recent evidence suggests that the delivery of human mesenchymal stem cells (hMSCs) to the infarcted heart improves mechanical function in both clinical and experimental animal studies, although the functional mechanism remains equivocal. A major limitati | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $38,042 | Grant | Trans-NIH Recovery Act Research Support: This award was an administrative supplement in support of An Open-Source Algorithm Isolating Overlapping Signatures in Microarray Data. The primary request of this supplement was for funds to provide for the purchase of high-powered computational nodes de | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $71,200 | Grant | Trans-NIH Recovery Act Research Support: Despite significant advances in the treatment of cancer over the past several decades, there are no longterm effective therapies for glioblastoma multiforme GBM. The aims of the project have focused on the use of expanded/activated T cells as adjuvant im | Health and Human Services, Department of / National Institutes of Health | 8/20/2009 |
| UNIVERSITY OF TEXAS M.D. ANDERSON CANCER CENTER, THE | $17,864 | Grant | Trans-NIH Recovery Act Research Support: Facioscapulohumeral muscular dystrophy (FSHD) is a progressively debilitating syndrome that is the nation's third most common type of dystrophy, yet the development of directed therapies remains hampered by our poor understanding of its molecular basis. R | Health and Human Services, Department of / National Institutes of Health | 7/19/2009 |
| UNIVERSITY OF ROCHESTER | $744,313 | Grant | Trans-NIH Recovery Act Research Support: The main Rochester Human Immunology Center grant supports development and deployment of expertise in sophisticated immunological assays, but the original application did not support biochemical purification and conjugation of proteins. As production of a | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| UNIVERSITY OF ROCHESTER | $113,194 | Grant | Trans-NIH Recovery Act Research Support: The project is to generate transgenic clone of Xenopus with modulated expression of MHC class I, and to generate Xenopus mono-specific antibodies against immunologically important molecules. The overall objective of this renewal application is to safegu | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| TEXAS STATE UNIVERSITY-SAN MARCOS | $649,723 | Grant | Trans-NIH Recovery Act Research Support: Xiphophorus fishes have been used as an experimental model for fundamental biomedical research for over 75 years. Eventually 'mechanistic' hypothesis must be confirmed using intact animal model systems. Well-characterized diverse experimental animal model | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF HAWAII SYSTEMS | $154,872 | Grant | Trans-NIH Recovery Act Research Support: The broad long-term goal of this proposal is to increase the representation of individuals, who are underrepresented ethnic minority or of socio-economically disadvantaged background, in biomedical and social sciences research. To this end, the University | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY | $172,800 | Grant | Trans-NIH Recovery Act Research Support: We request support for mentored research training of a U.S. postdoctoral scientist to establish the Haiti HIV/AIDS Policy Model in collaboration with Haitian investigators. This computer simulation model will project the clinical consequences and costs of | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| UNIVERSITY OF NEBRASKA | $172,800 | Grant | Trans-NIH Recovery Act Research Support: The impact of the HIV/AIDS epidemic is devastating, especially in sub-Saharan Africa where almost two-thirds of the population living with HIV/AIDS resides. While it is well established that a substantial number of untreated HIV-1 patients ultimately deve | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $86,363 | Grant | Trans-NIH Recovery Act Research Support: This award is entitled Fogarty ARRA Supplement for US Global Health Postdoctoral Scientist Support (American Recovery and Reinvestment Act of 2009, NOT-OD-056). It builds on over 20 years of collaboration between Johns Hopkins University (JHU) and Aga Kha | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| NEW YORK UNIVERSITY (INC) | $41,428 | Grant | Trans-NIH Recovery Act Research Support: New York University School of Medicine and the National Institute of Malaria Research (NIMR), India, have a five year joint Fogarty Global Infectious Disease training and research grant. The aim of this grant is to provide research training into the biol | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| THE JACKSON LABORATORY | $65,930 | Grant | Trans-NIH Recovery Act Research Support: ENHANCING THE JAXMICE DATABASE RESOURCE Many factors have converged to lead to a rapid increase in the use of mouse models in biomedical research, and in the rate that new mouse strains are being generated. These include: the completion of the mouse genom | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| MEHARRY MEDICAL COLLEGE | $500,000 | Grant | Trans-NIH Recovery Act Research Support: This supplement will evaluate the use of green tea and a major component in green tea epigallocatechin gallate (EGCG) to determine if the tea can provide symptomatic relief of uterine fibroids. A second year of funding was received through a non competing | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY | $108,000 | Grant | Trans-NIH Recovery Act Research Support: A notable recent advance in psychiatry is the recognition that mental health problems can originate in-utero. Research in developmental psychopathology has shown that preterm birth is associated with a 2- to 3-fold increased risk of both disruptive behavi | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $34,791 | Grant | Trans-NIH Recovery Act Research Support: This ARRA Summer Student Supplement to my K01 award was designed to : 1. encourage students to pursue research careers in health-related sciences and 2. to accelerate the progress of the parent grant. The funds support two high school and two undergradu | Health and Human Services, Department of / National Institutes of Health | 7/19/2009 |
| UNIVERSITY OF TEXAS M D ANDERSON | $101,218 | Grant | Trans-NIH Recovery Act Research Support: My career goal is to become an established researcher in the molecular epidemiology of cancer. This goal builds upon my previous education and training in medicine and epidemiology but requires further training in molecular techniques and genetic epidemio | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $107,342 | Grant | Trans-NIH Recovery Act Research Support: This proposal is designed to enrich Andrew T. Chan, MD's career development in cancer prevention epidemiology through an integration of mentored research experience with formal coursework at the Harvard School of Public Health. The proposed research aims | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $985,273 | Grant | Trans-NIH Recovery Act Research Support: As an extension of our existing MGI CEGS work, we propose to develop methods for measuring mRNA splice isoform distributions in 100s to 1000s of genes in large numbers of individual human cells, and to demonstrate these methods on differentiating induced | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| MCLEAN HOSPITAL CORPORATION, THE | $98,876 | Grant | Trans-NIH Recovery Act Research Support: This is an amended competitive continuation grant of the Udall Parkinson's Disease Research Center of Excellence at Harvard University and McLean Hospital, which is directed by Professor Ole Isacson. The Center performs scientific work on conceptually nov | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| MCLEAN HOSPITAL CORPORATION, THE | $131,408 | Grant | Trans-NIH Recovery Act Research Support: This is an amended competitive continuation grant of the Udall Parkinson's Disease Research Center of Excellence at Harvard University and McLean Hospital, which is directed by Professor Ole Isacson. The Center performs scientific work on conceptually nov | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| EMORY UNIVERSITY | $844,480 | Grant | Trans-NIH Recovery Act Research Support: The Yerkes National Primate Research Center (YNPRC) is one of the 8 NPRCs funded by a P51 grant from the NIH and NCRR to conduct basic and applied biomedical research using nonhuman primate (NHP) models to identify solutions for human health and societal | Health and Human Services, Department of / National Institutes of Health | 9/26/2009 |
| UNIVERSITY OF PITTSBURGH THE | $90,855 | Grant | Trans-NIH Recovery Act Research Support: The goal of this supplement to my KO1 award is to support my career goals of becoming a successful independent investigator with expertise on alcohol-induced changes in the immune system, developing a well-funded laboratory and training future alcohol res | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| ROCHESTER INSTITUTE OF TECHNOLOGY | $9,720 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement (part of NIH's stimulus funding) is to provide summer research experiences for students, and is a supplement to the PI's current NIH NIA K01 grant. Four undergraduate students (two each year) will participate on the project | Health and Human Services, Department of / National Institutes of Health | 6/22/2009 |
| UNIVERSITY OF TEXAS M D ANDERSON | $50,000 | Grant | Trans-NIH Recovery Act Research Support: The primary cause of skin cancer is chronic exposure to ultraviolet (UV) rays from sunlight. A crucial event in the prevention of UV-induced skin cancer is the repair of DNA damage and / or the removal of the damaged cell through apoptotic mechanisms. Fai | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $92,114 | Grant | Trans-NIH Recovery Act Research Support: Telomeres are nucleoprotein structures that cap the ends of eukaryotic chromosomes and play crucial roles in preventing natural chromosome ends from being recognized as damaged DNA, thus ensuring genomic stability. Dysfunction of telomeres would lead to D | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF LOUISVILLE | $52,823 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this AARA supplement is to support the stipend of Timothy D. Cummins, a PhD candidate in the Department of Biochemistry and Molecular Biology at the University of Louisville School of Medicine. The primary focus of Tim's dissertation work | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $52,400 | Grant | Trans-NIH Recovery Act Research Support: The ARRA-funded part of the project entitled !The Role of FGFR1 and FGFR2 in Repair of Damaged Intestinal Epithelium! is set aside to fund tissue processing and histological services associated with the parent grant. In addition, a portion of the funds wi | Health and Human Services, Department of / National Institutes of Health | 8/24/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $104,120 | Grant | Trans-NIH Recovery Act Research Support: Sunlight is an environmental risk factor for skin cancer. A great deal of work has been done to characterize and quantify sun exposure. However, sun exposure risk estimates for melanoma, squamous cell carcinoma and basal cell carcinoma vary widely. As the | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $74,774 | Grant | Trans-NIH Recovery Act Research Support: In order to make informed public health decisions based on cost-effectiveness analyses, new simulation models of HPV and cervical cancer need to be created by decision analysts who have expertise across a broad array of subjects that reflects the complex | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $45,335 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of the proposed research is to identify genetic and behavioral factors which influence cancer risk and prevention efforts of individuals with inherited predisposition for colorectal cancer (CRC). Clinical genetic testing has become incr | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| WAYNE STATE UNIVERSITY (INC) | $107,484 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this research plan is to investigate the importance of chromosome 6 on lung cancer and COPD development. This proposal describes a five-year plan to acquire knowledge and skills to become an independent cancer researcher, with special | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF TEXAS M D ANDERSON | $29,688 | Grant | Trans-NIH Recovery Act Research Support: My long-term goal is to become an established independent bio-behavioral epidemiologist and to design, implement and analyze studies that combine genetic and non-genetic influences on behaviors that effect cancer and other health outcomes. My proposal bui | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF ARIZONA | $95,172 | Grant | Trans-NIH Recovery Act Research Support: Non-melanoma skin cancer (NMSC) is a large and growing burden on our healthcare system. The current K07 award studies the chemopreventive action of the natural product sulforaphane (SF) after UB exposure of the skin. This administrative supplement allows | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $49,999 | Grant | Trans-NIH Recovery Act Research Support: Neurotropic viruses are important causes of morbidity and mortality throughout the world. The lack of therapeutic options for these diseases is driven by the paucity of understanding of the mechanisms by which neurotropic viruses cause disease. We propose | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $54,000 | Grant | Trans-NIH Recovery Act Research Support: The candidate's goals are to develop into an outstanding clinical scientist with an independent laboratory based research program within the next 5 years. The candidate, and candidate's department, is committed to the specialized study necessary to achiev | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $108,000 | Grant | Trans-NIH Recovery Act Research Support: Rheumatoid arthritis (RA) is a chronic inflammatory disease that causes symmetric polyarthritis and joint destruction. Considerable work in the pathogenesis of RA has implicated multiple signaling pathways that regulate the production of pro-inflammatory | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $101,470 | Grant | Trans-NIH Recovery Act Research Support: This proposal describes experiments that have been performed by Ms. Heidi Bretscher and are being pursued by others in my laboratory to understand the relationship between chromatin structure and BRCA1 function in DNA repair. Ms. Bretscher was hired as a | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH | $105,684 | Grant | Trans-NIH Recovery Act Research Support: This award is issued in response to Notice OD-09-060, Recovery Act Administrative Supplements Providing Summer Research Experiences for Students and Science Educators. DESCRIPTION (provided by applicant): Dysfunction in cell cycle checkpoint promotes geno | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| CHILDRENS HOSPITAL OF PHILADELPHIA | $53,830 | Grant | Trans-NIH Recovery Act Research Support: The liver develops from cells of the ventral foregut endoderm which differentiate into heptoblasts and proliferate into the adjacent mesenchyme to form the liver bud. Most of these cells mature into hepatocytes, but some of those surrounding the portal v | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $54,000 | Grant | Trans-NIH Recovery Act Research Support: Roles for Phospholipase A2 Signaling in Prostate Development: The parental K08 award?s hypothesis focused on the role of cytoplasmic phospholipase A2 (cPLA2) in prostate development. This enzyme is a potent regulator of the inflammatory response and one o | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF ILLINOIS | $108,359 | Grant | Trans-NIH Recovery Act Research Support: This award is a supplement to the applicantG??s K08 award entitled Notch Signaling in the Corneal Epithelium. The primary purpose of this supplement is to hire a laboratory technician to perform critical and exciting experiments within the scope of the K0 | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF ILLINOIS | $175,392 | Grant | Trans-NIH Recovery Act Research Support: The molecular events that lead to proper patterning and reinnervation of the cornea following disease or injury remain largely unknown. The goal of our proposed research is to investigate keratocyte derived guidance cues to the regenerating axons during c | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| UNIVERSITY OF CHICAGO, THE | $105,191 | Grant | Trans-NIH Recovery Act Research Support: The long-term aim of the proposed research is to identify genetic variation contributing to diabetic retinopathy. There have been extensive research efforts to understand the genetics of diabetic retinopathy, however, linkage and candidate gene studies h | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| THE UNIVERSITY OF SOUTH DAKOTA | $107,741 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the requested administrative supplement is to cover the salary of Research Instructor Dr. Alicia A. Goyeneche for two years. Dr. Goyeneche was and will be essential for the completion of key objectives stated in the proposal. Dr. Goyeneche | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $45,413 | Grant | Trans-NIH Recovery Act Research Support: The Hepatitis C Virus (HCV) E2 glycoprotein is a novel kinase that initiates signal transduction mechanisms modulating the following pathways: 1.) Clathrin-mediated endocytosis, through a site-specific phosphorylation of the clathrin adaptor protein-50 (A | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF PITTSBURGH THE | $71,600 | Grant | Trans-NIH Recovery Act Research Support: Additional equipment acquisition to further advance the research in understanding the role of Kruppel-like zinc-finger transcription factors KLF4 and KLF5, two of the most abundant transcription factors in the mouse cornea, in regulating the normal develo | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| RUSH UNIVERSITY MEDICAL CENTER | $108,000 | Grant | Trans-NIH Recovery Act Research Support: The parent grant K23 AG030944 or Paul B. Beeson Award in Aging proposed to examine a broad set of 5 specific aims over 4 years (7/2008-6/2012) and to conduct a prospective, population-based epidemiological study of the relations of the overall self-neglec | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $50,000 | Grant | Trans-NIH Recovery Act Research Support: We requested funds to purchase an Ultra High Performance Liquid Chormatography (UHPLC), one of the newest analytical tools in liquid chromatography used for drug quantitation. The overall scope of the parent grant is to determine whether fluctuations in s | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF CONNECTICUT | $53,392 | Grant | Trans-NIH Recovery Act Research Support: Oral Mucositis refers to erythematous, erosive and ulcerative lesions of the oral mucosa seen in almost 100% of patients treated for head and neck cancer, with radiation therapy to fields involving the oral cavity. These lesions are painful, significantl | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $54,000 | Grant | Trans-NIH Recovery Act Research Support: While the prognosis of early stage head and neck squamous cell carcinoma is excellent with standard surgical and chemo-radiation treatment strategies, effective treatment modalities for advanced or recurrent disease are lacking. Various immunotherapy clin | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| THE VANDERBILT UNIVERSITY | $53,946 | Grant | Trans-NIH Recovery Act Research Support: Patient education is a priority and desired by both patients and providers in the care of chronic kidney disease (CKD). Yet, even in the setting of frequent interactions with health care providers, patients often report low knowledge of chronic diseases, | Health and Human Services, Department of / National Institutes of Health | 9/20/2009 |
| UNIVERSITY OF ROCHESTER | $54,000 | Grant | Trans-NIH Recovery Act Research Support: A one-year supplement is requested to accelerate the tempo of a K23 Award focused on the translation of efficacious interventions to community settings. Since the time of initial funding, two new settings have opened one local, one national in scope that | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| UNIVERSITY OF IOWA, THE | $107,853 | Grant | Trans-NIH Recovery Act Research Support: The final resubmission of a Mentored Patient-Oriented Career Development Award Application (K23) to support Dr. Lisa Segre's development as an academic research scientist with expertise in the development of perinatal depression treatments for low-income | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UMDNJ-ROBERT WOOD JOHNSON MEDICAL SCHOOL | $108,000 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Depression, the most common psychiatric disturbance in Parkinson's disease (PD), is linked with a faster progression of physical symptoms, greater cognitive decline, and poorer quality of life. Despite the fact that un | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| BENAROYA RESEARCH INSTITUTE AT VIRGINIA MASON | $54,000 | Grant | Trans-NIH Recovery Act Research Support: Serum ferritin is the accepted laboratory marker for body iron stores and is also an acute phase reactant known to be elevated in inflammation. Elevated serum ferritin levels have been associated with the presence of diabetes, metabolic syndrome and nonal | Health and Human Services, Department of / National Institutes of Health | 7/28/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $54,000 | Grant | Trans-NIH Recovery Act Research Support: This Administrative Supplement will support hiring of additional personnel to allow expansion of the ongoing clinical trial to up to 5 additional sites. The clinical trial tests the hypothesis that adding or increasing the mesalamine dose can reduce fecal | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON | $107,957 | Grant | Trans-NIH Recovery Act Research Support: The incidence of Hepatitis C Virus (HCV) infection in the general population is growing significantly which is of great concern. The progression of the viral infection as well as treatment modality critically depends on the patient's stage of fibrosis. Th | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $129,217 | Grant | Trans-NIH Recovery Act Research Support: Award Title: Neighborhood Socioeconomic Environments and Pathways to Coronary Heart Disease. The goal of this K99 Administrative Supplement is to provide additional funded time to enable the Principal Investigator (PI) to secure a tenure-track faculty | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $889,235 | Grant | Trans-NIH Recovery Act Research Support: Insufficient sleep is a major health and safety problem for Americans. National polls indicate that more than a quarter of adults 18-84 years of age regularly sleep less than 7 h per night, with 15% reporting sleeping less than 6 h per night. The deficits | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $97,772 | Grant | Trans-NIH Recovery Act Research Support: Sleep in older people is marked by difficulty with initiation, frequent arousals, and early awakening. While the consequences of acute sleep deprivation have been investigated in older people, very little is known about the consequences of the chronic ins | Health and Human Services, Department of / National Institutes of Health | 7/21/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $279,999 | Grant | Trans-NIH Recovery Act Research Support: The Experience Corps-? is a community-based model for health promotion for older adults embedded within a social engagement program. Our study population is predominantly older, African-American women in Baltimore City. The program incorporates health pro | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| DANA-FARBER CANCER INSTITUTE, INC. | $617,662 | Grant | Trans-NIH Recovery Act Research Support: During prior funding periods, we have produced, crystallized and determined the structure of human (h) CD4 sCD41-183 and HIV-gp41 to high resolution. The structure of hsCD4 in complex with an MHC class II molecule (hsSCD4-pMHCII) was also solved. In conju | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| NEW YORK UNIVERSITY (INC) | $436,997 | Grant | Trans-NIH Recovery Act Research Support: The purposed investigations will extend for one year an ongoing study of HIV-specifi cellular immune responses developing during acute and recent HIV infection. HIV-specific responses are assessed by HIV antigen stimulation of cytokines as measured by int | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $29,329 | Grant | Trans-NIH Recovery Act Research Support: This was an administrative supplement to Project 2 of the PO1 entitled Bone Marrow Transplantation in Human Disease. Work by Borrello and colleagues recently focused on increasing the overall efficacy of adoptive T cell therapy. Specifically, the initial | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| HENRY FORD HEALTH SYSTEM | $18,702 | Grant | Trans-NIH Recovery Act Research Support: The purpose of thei Administrative Supplement is to give a college student who is considering a career in health-related sciences the opportunity to learn how new medicines are developed and evaluated in humans in a real world setting. At the completion | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $366,123 | Grant | Trans-NIH Recovery Act Research Support: Our goal is to enable researchers using X-ray crystallography to obtain better three-dimensional structures of biomolecules and hence better understanding of the underlying biology. To this end we have brought together a highly collaborative team of resea | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF WASHINGTON | $940,400 | Grant | Trans-NIH Recovery Act Research Support: This is an application for a competitive supplement to our program project grant entitled: ''Human Embryonic Stem Cell Self Renewal and Differentiation' (1P01GM081619). In Project 1 of our P01 we found that a narrow concentration of sodium butyrate can e | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF HOUSTON SYSTEM | $120,000 | Grant | Trans-NIH Recovery Act Research Support: The objective of this request for an administrative supplement to HD 2 P01 HD35946-10 (Spina Bifada: Cognitive and Neurobiological Variability) is to accelerate the rate at which the science of the project can be completed. Specifically, we wish to acce | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $63,464 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The overall purposes of this program-project grant (PPG) are to understand how iron deficiency alters brain and behavior in early development and identify interventions that will correct or prevent ill effects in the s | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF ROCHESTER | $143,850 | Grant | Trans-NIH Recovery Act Research Support: Stroke remains the third leading cause of death in the US, behind heart disease and cancer. Each year 750,000 Americans suffer a diagnosed stroke and this number will double by 2050, given the advancing average age of the population, barring further devel | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $749,774 | Grant | Trans-NIH Recovery Act Research Support: Routine use of mediated and interpersonal sources provides a substantial amount of information relevant to cancer prevention (e.g. exercise, fruit and vegetable consumption) and screening (e.g. mammography, colon cancer screening, PSA). The issue is whet | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF MARYLAND | $112,350 | Grant | Trans-NIH Recovery Act Research Support: Cancer in Maryland, and its impact on the health of minority and underserved rural populations, is a particularly serious health care dilemma. In fact, Maryland now ranks 7th nationally in cancer incidence, and significant disparities are seen between Afr | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| MONTANA STATE UNIVERSITY, INC | $600,000 | Grant | Trans-NIH Recovery Act Research Support: This project aims to address the health concerns and reverse the health disparities experienced by Native Americans living in Montana. Our experience is insistent that the necessary approach to scientific inquiry and health enhancement for this population | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $86,464 | Grant | Trans-NIH Recovery Act Research Support: The Rural Health Care Research Center (RHCRC), an interdisciplinary research center located in the School of Nursing at the University of Virginia is funded by the National Institutes of Health National Institute of Nursing Research for the time period of | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| MAINE MEDICAL CENTER | $201,238 | Grant | Trans-NIH Recovery Act Research Support: Maine Medical Center Research Institute has a successful COBRE in Vascular Biology that has been funded since 2000. The goal of the COBRE is to understand critical signaling pathways that regulate cardiovascular development and disease, using mouse models | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| THE UNIVERSITY OF SOUTH DAKOTA | $149,818 | Grant | Trans-NIH Recovery Act Research Support: Expression of stress-related behaviors is appears to be mediated by particular monoaminergic circuits within the brainG??s limbic system, and stress-induced disruption of these systems is thought to generate maladaptive stress and anxiety states. The goa | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| BROWN UNIVERSITY IN PROVIDENCE IN STATE OF RI AND PROVIDENCE PLANTATIONS | $387,065 | Grant | Trans-NIH Recovery Act Research Support: Administrative supplement for the project titled Center for Cancer Signaling Networks. This supplement will allow us to support an additional young investigator on our COBRE and hire a research assistant and provide supplies. The specific aims of this s | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| UNIVERSITY OF NEVADA, RENO | $200,000 | Grant | Trans-NIH Recovery Act Research Support: Research progress by COBRE Projects 1 and 4 and the COBRE Transgenic Core has recently identified ClC-3, a member of the super-family of ClC chloride channels, as a molecular candidate for volume-sensitive outwardly rectifying anion channels (VSOACs) in t | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF IDAHO | $89,367 | Grant | Trans-NIH Recovery Act Research Support: Support from the COBRE funding over the last 9 years has contributed to the establishment and growth of a nationally recognized program in microbial pathogenesis at the University of Idaho. Our currently funded COBRE program continues to focus on buildin | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| UNIVERSITY OF NEBRASKA | $499,826 | Grant | Trans-NIH Recovery Act Research Support: The Nebraska Center for Virology (NCV) is making tremendous strides toward achieving its goal of understanding how viruses cause disease. However, the center is hindered by a lack of center-funded research capable of translating findings directly from the | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF ALASKA FAIRBANKS | $30,555 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of the proposed COBRE-funded Center for Alaska Native Health Research (CANHR) is to achieve a permanent and sustainable research center at the University of Alaska Fairbanks (UAF) with the primary theme of investigating obesity and chroni | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE | $182,207 | Grant | Trans-NIH Recovery Act Research Support: The goals of the COBRE Neuroscience Supplement 3P20 RR016435-09S1 are to increase the number of students and enhance their experience in a Neuroscience COBRE-supported Summer Neuroscience Undergraduate Research Fellowship (SNURF) at the University of Verm | Health and Human Services, Department of / National Institutes of Health | 8/25/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $307,533 | Grant | Trans-NIH Recovery Act Research Support: The objectives of the original application for the Core B (the Immune Monitoring Laboratory (IML)) were: (i) to provide state-of-the-art immunoassays to allow COBRE Investigators to monitor and evaluate immune responses; (ii) to provide quality control an | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF IDAHO | $395,942 | Grant | Trans-NIH Recovery Act Research Support: Accounting for evolutionary change in infectious agents represents a key challenge for medicine in the 21st century. Examples of rapid evolution of pathogens affecting human health abound. Particularly relevant is the evolution of antibiotic resistance le | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF IDAHO | $600,000 | Grant | Trans-NIH Recovery Act Research Support: This NCRR Administrative Supplement to the Idaho INBRE Program parent award is for a collaborative project with the University of Washington's Clinical and Translational Science Award (ITHS). The proposal is within the scope of the scientifically-reviewe | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE | $850,187 | Grant | Trans-NIH Recovery Act Research Support: This Request is the Vermont portion of a regional effort from the northeast IDeA states (VT, NH, ME, RI and DE) to provide the first fiber-optic backbone through northern New England that connects higher-education and biomedical research institutions for | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE | $198,660 | Grant | Trans-NIH Recovery Act Research Support: The Vermont IDeA Network for Biomedical Excellence is the Vermont Genetics Network (VGN). We build biomedical research capacity throughout the state by developing facilities such as for Microarray and Proteomics, providing Bioinformatics services, suppor | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| MOUNT DESERT ISLAND BIOLOGICAL LABORATORY (INC) | $282,704 | Grant | Trans-NIH Recovery Act Research Support: The Maine IDeA Network of Biomedical Research Excellence (ME-INBRE) seeks to expand its successful research training program and to enhance regional collaborations with other IDeA programs by creating a new research training course for first year medical | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF NEVADA, RENO | $340,000 | Grant | Trans-NIH Recovery Act Research Support: The goal of the project is to increase colorectal cancer screening within the priority population of female and male adults age 50 to 85 in Northern Nevada. The screening program will be developed from the successful cancer patient navigator program opera | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $587,298 | Grant | Trans-NIH Recovery Act Research Support: This supplement falls within the scope of the parent grant as we are proposing to provide new training opportunities to clinical researchers interested in oral health research. Our infrastructure and experience gained with the Gullah population have led u | Health and Human Services, Department of / National Institutes of Health | 9/08/2009 |
| NEMOURS FOUNDATION | $958,810 | Grant | Trans-NIH Recovery Act Research Support: The primary goal of this COBRE proposal was to increase the number of active, NIH-funded biomedical researchers in the State of Delaware. This was accomplished through the efforts of a multidisciplinary group of investigators at the Nemours Research Insti | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF MISSISSIPPI | $584,617 | Grant | Trans-NIH Recovery Act Research Support: The Center for Research Excellence in Natural Products Neuroscience (COBRE-NPN) has an in vitro pharmacology Core (Core C) that has established numerous G-protein Coupled Receptor ligand binding assays (GPCRs), second messenger and enzyme assays, all devo | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| RHODE ISLAND HOSPITAL | $966,823 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this project is to utilize the new knowledge gained from studying the basic mechanisms of cartilage/joint diseases, thereby developing novel therapies to treat these diseases. Our investigators have made several novel findings recently, whi | Health and Human Services, Department of / National Institutes of Health | 8/20/2009 |
| UNIVERSITY OF FLORIDA | $219,747 | Grant | Trans-NIH Recovery Act Research Support: This revision expands the focus of the OAIC to mitochondrial function and fatigue. Fatigue is a major complaint among older adults and is strongly associated with loss of independence and impairments regardless of underlying medical conditions. Multiple b | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| NORTHWESTERN UNIVERSITY | $50,000 | Grant | Trans-NIH Recovery Act Research Support: This supplement is for the recruitment of new faculty in NCI Designated Cancer Center (P30) and in Minority Serving Institutions funded through the U54 Comprehensive Minority Institution/ Cancer Center Partnership | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $49,971 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement was awarded for participation in the new initiative entitled ADOPTion of New Technologies for Remote Data Capture and Protocol Authoring (ADOPT). It is intended to improve the efficiency and effectiveness of the clinical tri | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UMDNJ-ROBERT WOOD JOHNSON MEDICAL SCHOOL | $50,000 | Grant | Trans-NIH Recovery Act Research Support: Participation in the ADOPTion of New Technologies for Remote Data Capture and Protocol Authoring (ADOPT) initiative by the NCI, which is intended to improve the efficiency and effectiveness of the clinical trials process and reduce clinical trial costs, t | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $298,017 | Grant | Trans-NIH Recovery Act Research Support: The members of the Center for Gastrointestinal Biology and Disease (CGIBD) are basic and clinical scientists from diverse disciplines dedicated to advancing our understanding of gastrointestinal biology, physiology and epidemiology with a special emphasis | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $282,993 | Grant | Trans-NIH Recovery Act Research Support: The Specific Aim of this supplement is to provide optimized, state of the art spinning disk confocal and live cell imaging within the Morphology Core for members of the Center for Molecular Studies in Digestive and Liver Disease at the University of Penns | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| DUKE UNIVERSITY | $309,808 | Grant | Trans-NIH Recovery Act Research Support: Overview and Specific Aims In April, 2004, the Center for Comparative Biology of Vulnerable Populations (CCBVP) was established at Duke University as part of NIEHS?s portfolio of Environmental Health Sciences Research Centers. The CCBVP has achieved dist | Health and Human Services, Department of / National Institutes of Health | 9/02/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $484,114 | Grant | Trans-NIH Recovery Act Research Support: This supplement requests support for the CEET to build capacity in its core mission which is to elucidate the mechanistic link between environmental exposures and human disease and translate these findings to improvements in patient and public health. | Health and Human Services, Department of / National Institutes of Health | 9/02/2009 |
| UNIVERSITY OF WASHINGTON | $339,426 | Grant | Trans-NIH Recovery Act Research Support: Administrative Supplement to the University of Washington and UC Davis Fragile X Research CenterOverview of the scope of the supplement, anticipated contribution of the supplement and importance to the Recovery ActOur Fragile X Center combines work in t | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $154,223 | Grant | Trans-NIH Recovery Act Research Support: UAB is one of Americas premier research universities, ranking among the top 20 in funding from the National Institutes of Health and earning more than $360 million per year in contract and grant support, with more than $250 million per year of extramural | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| TRUSTEES OF TUFTS COLLEGE INC | $44,194 | Grant | Trans-NIH Recovery Act Research Support: This award is intended to provide a summer research experience for an undergraduate student with an interest in pursuing a career in neuroscience and to accelerate the tempo of work on the parent grant. The parent grant provides essential research servic | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| TRUSTEES OF TUFTS COLLEGE INC | $153,147 | Grant | Trans-NIH Recovery Act Research Support: The P41 Tissue Engineering Resource Center (TERC) was initiated in August 2004 after formal review by the NIH and was recently renewed for another five years. The initial focus for TERC (first five years) was on functional tissue engineering achieved thr | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $226,713 | Grant | Trans-NIH Recovery Act Research Support: The primary goals of the supplementary effort are three-fold: (1) To provide an ongoing mechanism to test and evolve force fields. (2) To provide an ongoing mechanism to test and evolve conformational search methods. (3) To provide a communication sys | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $669,574 | Grant | Trans-NIH Recovery Act Research Support: This project, which is a supplement to the NCRR-funded P41 Synchrotron Radiation Structural Biology Resource at Stanford, has the specific aim of developing, improving through collaborative research and applications, and disseminating a new integrated pip | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| BROOKHAVEN SCIENCE ASSOCIATES, LLC | $853,840 | Grant | Trans-NIH Recovery Act Research Support: Title: Macromolecular Crystallography at the National Synchrotron Light Source. Description: We are constructing an integrated facility at beamline X26-C of the National Synchrotron Light Source (NSLS) for single crystal X-ray diffraction and spectrosco | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $45,900 | Grant | Trans-NIH Recovery Act Research Support: The most important function of the Administrative core is to facilitate communication and thus interaction among research projects and cores. This exchange promotes a structure and atmosphere where interdisciplinary research and training takes place. Its | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $213,514 | Grant | Trans-NIH Recovery Act Research Support: Biomarkers of Exposure to Hazardous Substances Administrative Supplement to Core A and in collaboration with investigators at Arizona State University. Research carried out in the past at the University of California, Davis (UCD) and Arizona State Univer | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $215,195 | Grant | Trans-NIH Recovery Act Research Support: ARRA -SBRP: Environmental Exposure and Effect of Hazardous Chemicals(Administ RTC collaboration with NC DHHS Reducing Risk from Well Water Contamination: The RTC is partnering with the Medical Evaluation and Risk Assessment (MERA) program of the North Car | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $436,052 | Grant | Trans-NIH Recovery Act Research Support: The overall objective of this Superfund Basic Research Program Project on toxic metals is to understand the human health impact of exposure to arsenic and mercury from environmental and anthropogenic sources. This program consists of three biomedical and | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| UNIVERSITY OF KENTUCKY | $221,038 | Grant | Trans-NIH Recovery Act Research Support: We seek to obtain funds from the Recovery Act Funds for Administrative Supplements program (NOT-OD-09-056) in order to create new jobs in the field of environmental toxicology and to enhance research collaborations between the University of Kentucky Super | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $256,677 | Grant | Trans-NIH Recovery Act Research Support: This supplemental funding will provide support for a collaboration between Boston University's Superfund Basic Research Program Research Translation Core and the Cambridge Health Department. The Boston University Superfund Research Program is an interdisc | Health and Human Services, Department of / National Institutes of Health | 9/10/2009 |
| OREGON STATE UNIVERSITY | $235,584 | Grant | Trans-NIH Recovery Act Research Support: Polycyclic Aromatic Hydrocarbons (PAHs), re-emerging environmental pollutants of concern, found at Superfund sites and urban settings, are formed in the burning of carbon-based energy sources, e.g., diesel, gasoline, coal, petroleum and in cooking or toba | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $67,458 | Grant | Trans-NIH Recovery Act Research Support: This award is for the purchase of a Neuro-CCD-SMQ imaging system to be used in a project focused on defining how ethanol alters patterns of activity in neurons of the prefrontal cortex, a brain area critical for cognition, learning and control of behavior | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $163,548 | Grant | Trans-NIH Recovery Act Research Support: With this application, we propose adding a Summer Student Seed Grant component to our existing Developmental Research Program (DRP). We propose employing eight undergraduate student awards at $10,360 each to conduct research related to prostate cancer du | Health and Human Services, Department of / National Institutes of Health | 6/02/2009 |
| DANA-FARBER CANCER INSTITUTE, INC. | $352,826 | Grant | Trans-NIH Recovery Act Research Support: This application represents a renewal application of the Dana Farber Harvard Cancer Center (DF/HCC) Prostate Cancer SPORE. The application involves basic, translational and clinical investigators from several Harvard Institutions including the Beth Israel | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF PITTSBURGH THE | $379,250 | Grant | Trans-NIH Recovery Act Research Support: Lung cancer is the most common cause of cancer mortality in male and female patients in the US. The etiology of non-small cell lung cancer (NSCLC) is not fully defined, but new data suggest that estrogens as well as growth factors promote its progression. | Health and Human Services, Department of / National Institutes of Health | 9/08/2009 |
| UNIVERSITY OF TEXAS M D ANDERSON | $246,751 | Grant | Trans-NIH Recovery Act Research Support: SPORE IN MELANOMA | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $246,417 | Grant | Trans-NIH Recovery Act Research Support: This ARRA award encompasses two separate requests that were funded in support of the UAB SPORE in Neurological Cancer, P50CA097247. A $146,417 request was awarded to fund basic and translational research efforts and a $100,000 request was awarded to purc | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $75,638 | Grant | Trans-NIH Recovery Act Research Support: These grant monies provide salaries for summer research employment for 5 students who are active in their undergraduate studies. The goal is to provide employment in a manner that will mentor college students towards a career in biomedical research. | Health and Human Services, Department of / National Institutes of Health | 6/19/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $289,230 | Grant | Trans-NIH Recovery Act Research Support: Polycystic kidney disease (PKD) is a common genetic disease that is characterized by the development of fluid filled cysts in the kidney and is associated with high morbidity and mortality. Autosomal dominant PKD (ADPKD) affects approximately 1:1000 indiv | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF PITTSBURGH THE | $2,314,994 | Grant | Trans-NIH Recovery Act Research Support: Research to be conducted under the ARRA mechanism will accelerate the scientific tempo of a trial designed to understand the efficacy, mechanisms, and cost-effectiveness of alternative resuscitation strategies for septic shock. Trial recruitment will be e | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $786,000 | Grant | Trans-NIH Recovery Act Research Support: The proposal is for an administrative supplement to P60 DK-079626 entitled UAB Diabetes Research and Training Center. This research program has been funded by NIDDK since April 1, 2008, and will continue until February 28, 2013. The scope of the administ | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| ALLEGHENY-SINGER RESEARCH INSTITUTE | $434,047 | Grant | Trans-NIH Recovery Act Research Support: This Competitive Revision for 5R00DE018188-03 proposes to expand the parent project to include a non-viral method of gene delivery based upon ultrasound destruction of DNA-associated microbubbles. This ultrasound-assisted gene transfer (UAGT) works diffe | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF MARYLAND | $50,000 | Grant | Trans-NIH Recovery Act Research Support: Many human congenital and hereditary malformations, diseases and cancers directly result from abnormalities that occur during neural crest development. The neural crest, a population of migratory cells derived from the future central nervous system in the | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| MINNEAPOLIS MEDICAL RESEARCH FOUNDATION | $638,585 | Grant | Trans-NIH Recovery Act Research Support: To expand the scope of ongoing preclinical studies of nicotine vaccines as a therapeutic strategy for treating tobacco addiction, through the introduction of methods to deliver nicotine to rats via inhalation of cigarette smoke. These methods will be use | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| SRI INTERNATIONAL | $398,362 | Grant | Trans-NIH Recovery Act Research Support: The parent project: 'CNS Deficits: Interaction of Age and Alcoholism,' has documented the significant damage to central nervous system (CNS) structure and function caused by chronic alcohol dependence and has accumulated considerable longitudinal neuroima | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO ,THE | $96,615 | Grant | Trans-NIH Recovery Act Research Support: A series of experiments are proposed that will examine both the separate and the combined effects of alcohol and serotonin manipulations on two categorically distinct models of behavioral impulsivity (rapid-decision and reward-directed). To identify the t | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $293,692 | Grant | Trans-NIH Recovery Act Research Support: The proposed studies will provide important and novel data on environmental, situational, and individual factors in male and female adolescents who experience injuries. We will characterize the types of injuries and the exposure to alcohol in the communit | Health and Human Services, Department of / National Institutes of Health | 8/15/2009 |
| PENNSYLVANIA STATE UNIVERSITY, THE | $50,125 | Grant | Trans-NIH Recovery Act Research Support: Ethanol abuse and alcoholism remain very serious societal problems. A significant problem is the inability to diagnose alcohol abuse either in the general population or within selected groups of individuals such as adolescents and the recovering alcoholic | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UTAH STATE UNIVERSITY | $20,020 | Grant | Trans-NIH Recovery Act Research Support: Parent Grant Title: Behavioral Momentum of Alcohol Self-Administration AARA Supplement for Providing Summer Experiences for Students (3R01AA016786-02S1) This supplement provides summer research experiences for undergraduate students at Utah State Universi | Health and Human Services, Department of / National Institutes of Health | 6/17/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $325,000 | Grant | Trans-NIH Recovery Act Research Support: Diverse functions for nuclear factor kappaB (NF-?B) signaling have been established in a variety of cell types, but we are just beginning to identify a role in skeletal muscle (fiber) atrophy. The identification of a signaling pathway required for disuse | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF PITTSBURGH THE | $160,000 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplement is to integrate musculoskeletal modeling techniques with the existing study design for evaluating alterations in dynamic knee function after ACL injury/reconstruction. By combining our high-accuracy kinematic data with dyna | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $252,038 | Grant | Trans-NIH Recovery Act Research Support: The additional funds allowed us to accelerate progress towards achieving our original goals by providing for thegeneration of doxycycline inducible transgenic lines targeting the bulge. These lines will bevaluable to the scientific community. There have b | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $215,469 | Grant | Trans-NIH Recovery Act Research Support: Togavirus Tropism for Bones, Joints and CNS Alphaviruses such as Ross River virus (RRV) and chikungunya virus cause severe arthritis and mysositis in infected humans and represent a significant emerging infectious disease threat. An growing body of evi | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH, THE | $32,894 | Grant | Trans-NIH Recovery Act Research Support: This grant is for the purchase of a spectrophotometer/plate reader, an essential piece of equipment for the measurement of proteins, RNA, DNA, alcohol, etc in blood and brain samples. | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $26,000 | Grant | Trans-NIH Recovery Act Research Support: The present administrative supplement is for the purchase of an alcohol vapor inhalation system to expose mice 10 intermittent alcohol vapors to induce alcohol dependence as proposed in the original application. This request is motivated by the limited ca | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE | $187,810 | Grant | Trans-NIH Recovery Act Research Support: Alcohol-induced liver injury involves significant mitochondrial damage and up-regulation of inducible nitric oxide synthase (NOS2) leading to excessive generation of reactive oxygen species (ROS) and reactive nitrogen species affecting cell survival. Unde | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| THOMAS JEFFERSON UNIVERSITY | $50,000 | Grant | Trans-NIH Recovery Act Research Support: This Administrative Supplement provides funds for the purchase of scientific equipment (Cascade II Illuminating Camera), which will allow the implementation of cutting edge microscopy and fluorescent protein technology in the study of alcohol effect on mi | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $222,000 | Grant | Trans-NIH Recovery Act Research Support: Habits and cues in alcohol drinking: Dynamic striatal activity (ARRA) Parent grant activities. We are investigating real-time neurodynamics of the dorsal striatum in rats during alcohol drinking and relapse-like behavior (extinction/reinstatement). | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $162,362 | Grant | Trans-NIH Recovery Act Research Support: Early detection of Alzheimer's disease is moving from a pre-clinical mild cognitive impairment (MCI) to a pre-MCI stage. Of concern is the sensitivity of our measurement tools to detect more subtle changes in cognition. In the previously funded R01AG16495 | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $118,621 | Grant | Trans-NIH Recovery Act Research Support: The VETSA Longitudinal Twin Study of Cognition and Aging is a unique project that provides a comprehensive prospective examination of genetic and environmental influences on cognitive and brain aging with extensive data from neurocognitive, health/medical | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF MARYLAND | $66,823 | Grant | Trans-NIH Recovery Act Research Support: Investigate the mechanism of B-cell delivered tolerance in animal models, and then begin to translate these studies to the clinic using T Cells from MS patients exposed to B cells transdueced with MBP-Ig constructs in vitro. These studies will establish | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $50,013 | Grant | Trans-NIH Recovery Act Research Support: Definition of the molecular events of the innate immune response which are able to both contain and/or eliminate pathogenic challenges while preventing autoimmunity may provide clues towards novel therapeutic targets in the prevention of autoimmunity as w | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $314,817 | Grant | Trans-NIH Recovery Act Research Support: The main objective of the parent grant is to elucidate the mechanisms and factors controlling Tat-activation of HIV transcription. Recently, we have made great progress toward this goal. Using a double immunoprecipitation procedure, we have identified th | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $220,000 | Grant | Trans-NIH Recovery Act Research Support: Personnel All key personnel are in place. Research Summary. We have demonstrated that there is increased expression of NKG2D and NKG2D ligands, RAE1L and RRLT in liver allografts during acute rejection. These findings have been reported in a manuscri | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| TEXAS AGRILIFE RESEARCH | $22,896 | Grant | Trans-NIH Recovery Act Research Support: Cryptosporidium parvum is a unicellular pathogen that can cause severe watery diarrhea in humans and animals. This pathogen can cause one of the opportunistic infections in AIDS patients for which no complete effective treatment is yet available. Cryptosp | Health and Human Services, Department of / National Institutes of Health | 6/03/2009 |
| THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | $67,295 | Grant | Trans-NIH Recovery Act Research Support: Mycobacterium tuberculosis is a major opportunistic pathogen in patients with HIV/AIDS. Current tuberculosis treatment regimes are severely hampered by the occurrence of multidrug resistant strains of M. tuberculosis (MDR-TB) and there is a critical need | Health and Human Services, Department of / National Institutes of Health | 6/11/2009 |
| UNIVERSITY OF MEDICINE AND DENTISTRY OF NJ (INC) | $294,924 | Grant | Trans-NIH Recovery Act Research Support: These studies are aimed at characterization of the ADAM-mediated pathway responsible for generation of soluble MHC class I proteins that are thought to be involved in Ag cross-presentation and effector/target cell interactions and thus play an important r | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF MEDICINE AND DENTISTRY OF NJ (INC) | $641,803 | Grant | Trans-NIH Recovery Act Research Support: A major goal of this program is to identify and characterize anti-V1/V2 antibodies that possess broadly neutralizing activities. Towards this goal we have recently identified several sera that possess potent and broadly neutralizing activity for primary i | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF MONTANA SYSTEM | $60,392 | Grant | Trans-NIH Recovery Act Research Support: This project proposes to 1) enhance the state-of-the-art of molecular genetics of Borrelia burgdorferi and provide improved genetic tools for B. burgdorferi researchers and 2) train a local high school teacher. The hypothesis is that the trascriptional t | Health and Human Services, Department of / National Institutes of Health | 6/07/2009 |
| UNIVERSITY OF ILLINOIS | $15,643 | Grant | Trans-NIH Recovery Act Research Support: A The overall objective of the supplement is to accelerate research on the significance of a relatively less understood herpes simplex virus (HSV) type-1 entry receptor, 3-O sulfated heparan sulfate (3-OS HS). The availability of the supplement has facili | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $78,931 | Grant | Trans-NIH Recovery Act Research Support: In view of its wide availability and ease of purification, ricin has been employed as a toxic and lethal agent by totalitarian regimes and, recently, by terrorist groups. Ricin is a member of a family of ribosome-directed toxins whose toxicity stems from | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $309,561 | Grant | Trans-NIH Recovery Act Research Support: The overall aim of the parent grant (Role of the RNA-binding Protein HuR in Inflammation) and the supplemental funding is to understand the role of posttranscriptional gene regulation in the response of airway epithelium to inflammation, by focusing on th | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| NEW YORK UNIVERSITY (INC) | $45,880 | Grant | Trans-NIH Recovery Act Research Support: The immune system has evolved multiple regulatory mechanisms to protect the host from pathogens without the self-infliction of immune pathology through an unchecked response. There is now compelling evidence that a subset of T cells defined as CD4+CD25+ | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $32,800 | Grant | Trans-NIH Recovery Act Research Support: The goal of this proposal is to elucidate the pathway of programmed cell death by a novel antifungal agent and explore its use as an antimycotic adjunct. Amiodarone is an effective antiarrhythmic drug that was recently discovered to have potent and broad | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $284,527 | Grant | Trans-NIH Recovery Act Research Support: This award is issued in response to Notice OD-09-060, Recovery Act Administrative Supplements Providing Summer Research Experiences for Students and Science Educators. DESCRIPTION (provided by applicant): Plasmodium vivax malaria, a leading health proble | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| LOYOLA UNIVERSITY | $47,437 | Grant | Trans-NIH Recovery Act Research Support: The overall purpose of this award is to introduce undergraduate students to hands-on basic science research through a mentored summer research experience. The expected outcome is that undergraduate students will come to understand the importance of resea | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $76,014 | Grant | Trans-NIH Recovery Act Research Support: This award is issued in response to Notice OD-09-060, Recovery Act Administrative Supplements Providing Summer Research Experiences for Students and Science Educators. Adenoviruses cause 5-10% of respiratory illness in children and are associated with ac | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| GEORGETOWN UNIVERSITY (THE) | $98,811 | Grant | Trans-NIH Recovery Act Research Support: West Nile virus a human pathogen transmitted by mosquitoes and carried by birds as the reservoir. It causes considerable morbidity and mortality in human population in several countries including U.S.A. Dengue viruses cause ~50 million infections each ye | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| CHILDRENS HOSPITAL OF PHILADELPHIA | $155,780 | Grant | Trans-NIH Recovery Act Research Support: Regulatory T cells are crucial for the control of immune-mediated pathology during organ transplant rejection and autoimmune disease, therefore understanding the underlying mechanisms by which these cells function will be critical for promoting immune tol | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF PITTSBURGH THE | $167,810 | Grant | Trans-NIH Recovery Act Research Support: Dendritic cells (DC) are innate immune system cells that are critical in the host response to viral infection. DC are actively recruited to inflamed lymphoid and mucosal tissues where they produce inflammatory and antiviral cytokines and stimulate antigen | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| NEW YORK MEDICAL COLLEGE | $14,094 | Grant | Trans-NIH Recovery Act Research Support: The award was an administrative supplement to employ a highschool student for two summers to work full time on a project relevant to the parent grant. The goal of the award was to provide research experience to high school students, to liason with seconda | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $482,125 | Grant | Trans-NIH Recovery Act Research Support: This project responds to Notice NOT-OD-09-058, Enabling RPGs to Leverage NCRR Center and Center-like Programs. The overall goal of our research is to dissect the regulation of plasmacytoid dendritic cells (PDC) development and function at the molecular | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| AARON DIAMOND AIDS RESEARCH CENTER FOR THE CITY OF NEW YORK, INC, THE | $302,320 | Grant | Trans-NIH Recovery Act Research Support: The goal of the original R01 proposal is to develop a better animal model for HIV/AIDS. For more than 20 years, simian immunodeficiency virus infection of macaques has been a mainstay of AIDS research in animal models, and has been used both for pathogene | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON | $20,101 | Grant | Trans-NIH Recovery Act Research Support: The expression of Attaching and Effacing Escherichia coli (AEEC) virulence factors is a tightly regulated process, and, in some cases, the identification of these factors has been difficult because they are either repressed in vitro or the conditions of e | Health and Human Services, Department of / National Institutes of Health | 6/03/2009 |
| UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | $31,860 | Grant | Trans-NIH Recovery Act Research Support: The thymus is the primary lymphoid organ responsible for the production of T cells, and its function is required for the generation of cellular immunity in vertebrates. The stromal cell types in the thymus form a complex meshwork of microenvironments thro | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL | $160,517 | Grant | Trans-NIH Recovery Act Research Support: This supplemental award to R01 AR049722, entitled Glycosyltransferase therapies for myopathies. The overall purpose of this grant is for biomedical research. Specifically, the grant will investigate the role of dystroglycan in the ability of the Galgt2 | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| SEATTLE CHILDREN'S HOSPITAL | $193,417 | Grant | Trans-NIH Recovery Act Research Support: Early Aggressive Therapy in Juvenile Idiopathic Arthritis -- This administrative supplement will be used to make possible full enrollment and reach scientific completion of the randomized controlled trial (RCT) 1R01 AR049762-01A2: Multi-center Study | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| NORTHERN CALIFORNIA INSTITUTE FOR RESEARCH AND EDUCATION, INC. | $371,916 | Grant | Trans-NIH Recovery Act Research Support: This is a Competitive Revision Application entitled Vitamin D Receptor Coactivators in Keratinocytes in response to Notice Number NOT-OD-09-058 and Notice Title: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. T | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| GEORGIA TECH RESEARCH CORPORATION | $9,362 | Grant | Trans-NIH Recovery Act Research Support: Our overall goal is to understand the mechanisms that determine how cells and tissues respond to implanted materials in order to improve the function of devices and combination products used clinically. Studies using titanium (Ti) substrates suggest that | Health and Human Services, Department of / National Institutes of Health | 6/08/2009 |
| UNIVERSITY OF NORTH CAROLINA AT GREENSBORO | $155,102 | Grant | Trans-NIH Recovery Act Research Support: Hormone Mediated Knee Joint Laxity and Neuromichanics The primary aim of the parent grant is to determine the effects of greater absolute (ABSAKL) and cyclic (CYCAKL) changes in anterior knee joint laxity (AKL) on knee joint neuromechanics (muscle activat | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF OREGON | $66,765 | Grant | Trans-NIH Recovery Act Research Support: This supplement was used to fund research assistant positions for 3 undergraduate students and one recently graduated student for summer research. All of the research assistants gained valuable experience in biochemical methods during the summer months. | Health and Human Services, Department of / National Institutes of Health | 6/10/2009 |
| MAINE MEDICAL CENTER | $812,444 | Grant | Trans-NIH Recovery Act Research Support: The primary goal of this supplement is to investigate the role of retinaldehyde (Rald) in skeletal homeostasis and bone marrow adiposity. Our investigative group is studying the interaction between skeletal acquisition and bone marrow adiposity, and test | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | $168,000 | Grant | Trans-NIH Recovery Act Research Support: The leading cause of disability in the U.S. is arthritis, affecting approximately 60 percent of those over 65 years of age. Biomedical treatments are limited in their ability to curb osteoarthritis (OA) disease progression and to eliminate pain and functi | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| PENNSYLVANIA STATE UNIVERSITY, THE | $65,142 | Grant | Trans-NIH Recovery Act Research Support: The need for bone grafts to repair bone defects is rapidly accelerating as our population ages. Bone defects have been successfully treated using autografts and allografts. However, these are less than ideal approaches since autograft availability is limi | Health and Human Services, Department of / National Institutes of Health | 6/10/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $39,852 | Grant | Trans-NIH Recovery Act Research Support: This application is being submitted in response to ARRA funding call NOD OD 09 060 Administrative supplements providing summer research experiences for students and science educators. This proposal will fund two undergraduate students and one medical stud | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| MISSOURI SYSTEM, UNIVERSITY OF | $535,780 | Grant | Trans-NIH Recovery Act Research Support: ARRA Administrative Supplement to project: The work in this proposal is focused on a major cancer-preventive signal transduction pathway that triggers transcriptional induction of enzymes that protect cells from reactive chemical species, including carcin | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| THE VANDERBILT UNIVERSITY | $620,311 | Grant | Trans-NIH Recovery Act Research Support: Inflammatory bowel disease, consisting of ulcerative colitis and Crohn's disease, affects more than 1 million Americans and causes extensive morbidity. There is also a substantial risk of colitis-associated colon cancer. Our lab is focused on the role of | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| UNIVERSITY OF WASHINGTON | $310,850 | Grant | Trans-NIH Recovery Act Research Support: The ability of T cells to mediate in vivo anti-tumor effects in humans is well documented. Our laboratory has been using informative mouse models to study the potential efficacy of targeting tumors with adoptive T cell therapy, in which autologous tumor-r | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $651,648 | Grant | Trans-NIH Recovery Act Research Support: While integrin- and growth factor-mediated signaling pathways are thought to be critical for tumor invasion and metastasis, much remains to be elucidated regarding the specific kinases, phosphatases, proteases, and adaptor proteins that are essential for | Health and Human Services, Department of / National Institutes of Health | 8/07/2009 |
| ROCKEFELLER UNIVERSITY FACULTY AND STUDENTS CLUB INC, THE | $561,080 | Grant | Trans-NIH Recovery Act Research Support: This application is in response to Notice number NOT-OD-09-058 and Notice title: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. We propose to expand the scope of R01 CA57973-16 Structure and function of the HCV | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $348,264 | Grant | Trans-NIH Recovery Act Research Support: The ARRA research project was to determine !The Physiological Function and Regulation of INK4 Genes!, a family of genes that play a critical role in regulating cell proliferation and in tumor suppression. This funding under ARRA allowed us to initiate res | Health and Human Services, Department of / National Institutes of Health | 9/02/2009 |
| UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH | $31,175 | Grant | Trans-NIH Recovery Act Research Support: This grant provided a research experience for a science educator in health-related scientific research. | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $487,721 | Grant | Trans-NIH Recovery Act Research Support: Smoking is the primary cause of lung cancer in US adults, and also an important cause of mortality from other conditions. Onset of smoking occurs during adolescence. Research provides extensive documentation of social influence effects on initiation, espe | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| MAYO CLINIC | $99,602 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement application is under the parent grant entitled Alpha-1 Antitrypsin Deficiency and Lung Cancer Risk, R01 CA 80127, ending in May 2011 after a no-cost one-year extension. The proposed project is built on an established rich re | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $67,813 | Grant | Trans-NIH Recovery Act Research Support: The studies outlined in the parent grant serve to identify the paracrine interactions that occur between tumor cells and primary afferent neurons at a bone tumor site that lead to the development and transmission of cancer pain sensation. In the funded ad | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| THE WASHINGTON UNIVERSITY | $265,655 | Grant | Trans-NIH Recovery Act Research Support: Radiotherapy is constrained by toxicity to normal tissues. The parent R01 is focused on the development of increasingly-predictive models of normal tissue toxicity risk as a function of dose and volume of organs irradiated. The current specific aims focus | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | $505,473 | Grant | Trans-NIH Recovery Act Research Support: Appropriate implementation of Okazaki fragment maturation during DNA replication in eukaryotic cells is a fundamental mechanism for mutation avoidance and genome stability. During lagging strand DNA synthesis, multiple RNA primers and immediately adjoined | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| LOUISIANA STATE UNIVERSITY SYSTEM | $225,027 | Grant | Trans-NIH Recovery Act Research Support: The parent grant for this supplement has been funded since July 2000, at which time funding started at $135,000 direct costs/ year. Continuing funding for the parent grant occurred July 2006 by the competing renewal system with a 6.9 percentile funding sc | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | $151,510 | Grant | Trans-NIH Recovery Act Research Support: The overall aim of the project is to device strategies to overcome the poor immunity of tumor associated carbohydrate and glycopeptide antigens by employing three-component vaccine candidates composed of a tumor-associated carbohydrate-antigen such as MUC | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $85,908 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of the original R01 application (CA098932-06) is to identify potential prognostic markers of CRCs. The specific objectives of this funded grant were to develop strategies in assessing the clinical outcome of CRCs based on the underlying h | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| CASE WESTERN RESERVE UNIVERSITY | $404,590 | Grant | Trans-NIH Recovery Act Research Support: Ribonucleotide Reductase, (RNR) is a multi-subunit enzyme that catalyzes the rate-limiting step of de novo precursor DMA synthesis by converting nucleotide diphosphates to deoxynucleotide diphosphates. Crucial for rapidly proliferating cells, RNR is a tar | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY | $171,140 | Grant | Trans-NIH Recovery Act Research Support: Delivery of cell-killing doses of ionizing radiation to tumors is the objective of antibody-directed radioimmunotherapy (RIT). In practice however collateral damage to healthy bone marrow and kidneys limits the maximum delivered radiation dose. Pretarge | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| LOUISIANA STATE UNIVERSITY SYSTEM | $103,502 | Grant | Trans-NIH Recovery Act Research Support: Complete excision of cancer is guided by histologic assessment of surgical margins. Molecular detection of margins could allow for a better cure rate. Unfortunately, no marker is sensitive enough to be used reliably in a clinical setting. We have determin | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| GROUP HEALTH COOPERATIVE | $95,118 | Grant | Trans-NIH Recovery Act Research Support: Risk factors for pancreas cancer are not well established. Because of its near uniform and rapid case fatality, most studies of pancreas cancer have been small, had modest response rates and/or collected data exclusively from a surrogate respondent, and | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| TRUSTEES OF TUFTS COLLEGE INC | $136,089 | Grant | Trans-NIH Recovery Act Research Support: Epidemiological and experimental studies provide supportive evidence that lycopene, a major carotenoid from tomatoes and tomato products, may act as a chemopreventive agent against certain types of cancers. Our recent data from the parent grant R01CA1049 | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| FRED HUTCHINSON CANCER RESEARCH CENTER | $349,714 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this administrative supplement is to expand the sample size of our funded population-based case-control study by 10%, from 1,000 breast cancer cases and 1,000 population-based controls to 1,100 cases and 1,100 controls. This will enable thi | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $99,806 | Grant | Trans-NIH Recovery Act Research Support: Regular physical activity and a healthy diet can prevent and treat illnesses and prolong life, yet most Americans do neither. This proposal, PHLAME II (Promoting Healthy Living: Assessing More Effects), extends our original Behavior Change Consortium, NIH | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $238,732 | Grant | Trans-NIH Recovery Act Research Support: This proposal investigates the role of an RNA-binding oncoprotein in mammary tumorigenesis. This protein is located in the cytoplasm and binds to insulin-like growth factor-ll, p-actin, c-myc, and other mRNAs. We call it the c-myc Coding Region instabilit | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| WAKE FOREST UNIVERSITY | $99,895 | Grant | Trans-NIH Recovery Act Research Support: Progressive cognitive impairment occurs in up to 50% of primary and metastatic brain tumor patients who survive 6 months or longer after treatment with partial or whole-brain irradiation (WBI); ~200,000 patients/year receive these treatments. A growing bo | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $165,320 | Grant | Trans-NIH Recovery Act Research Support: The retinoblastoma (RB) gene is a potent suppressor of human cancers. In mammalian cells, two proteins related to the pRB protein, p107 and p130, display overlapping functions with pRB, including in the control of cell cycle, cell death and differentiatio | Health and Human Services, Department of / National Institutes of Health | 8/27/2009 |
| LOUISIANA STATE UNIVERSITY SYSTEM | $202,875 | Grant | Trans-NIH Recovery Act Research Support: Support for a postdoctoral associate is requested to accelerate the pace of this study, which is testing the hypothesis that rare or common genetic variants in the DNA damage-response pathway genes, either individually or in combination, are risk factors | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| DANA-FARBER CANCER INSTITUTE, INC. | $287,071 | Grant | Trans-NIH Recovery Act Research Support: We analyzed the gene expression and genetic profiles of all cell types composing normal breast tissue and in situ and invasive breast carcinomas using Serial Analysis of Gene Expression and SNP arrays, respectively. Based on these data we determined that | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $306,121 | Grant | Trans-NIH Recovery Act Research Support: Human papilloma viruses (HPVs) encompass the most common ?carcinogenic? viruses. An oncogenic role of ?high risk? mucosal HPVs has been established for anogenital carcinomas and other malignancies. Cutaneous HPVs of the genus beta type were deemed a pos | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| LOYOLA UNIVERSITY | $306,637 | Grant | Trans-NIH Recovery Act Research Support: The overall purpose of this award is to determine whether mindfulness based stress reduction influences the cholinergic anti-inflammatory pathways of women who are undergoing diagnosis and treatment for breast cancer. Assessment of biological outcomes wil | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF TEXAS HEALTHCARE AT TYLER | $0 | Grant | Trans-NIH Recovery Act Research Support: The objective of this administrative supplement is to examine how JAK/STAT3 pathway mediates chemopreventive properties of EGCG in vitro and KrasG12D transgenic mouse model in vivo, and assess whether inhibition of STAT3 can enhance the biological effects | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $17,004 | Grant | Trans-NIH Recovery Act Research Support: Support of undergraduate education and training in translational research | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $17,150 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this project is to study the inhibition of breast cancer progression by vitamin D analogs and triterpenoids. The specific aims of the parent grant are as follows: 1. To investigate the regulation of nuclear receptor and Smad signaling | Health and Human Services, Department of / National Institutes of Health | 6/11/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $15,128 | Grant | Trans-NIH Recovery Act Research Support: This proposal asked for an administrative supplement for a period of 03/01/2009-12/31/2013) to support a short-term research training experience for an undergraduate student, with an emphasis on minorities, in Summer 2009 and 2010. The purpose of the supp | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| NORTHWESTERN UNIVERSITY | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The first aim of this supplemental grant will increase the emphasis on two other TGF-beta receptor adaptor molecules, DAB2 and Axin. The second aim is to complete the development of reagents that are critical for the assessment of SARA protein in animal d | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $38,217 | Grant | Trans-NIH Recovery Act Research Support: ABSTRACT In this project we will use genetically engineered mouse models to probe mechanisms of cellular changes that progress to gastric metaplasia and cancer. Mice deficient in Huntingtin interacting protein 1 related (Hip1r) develop a progressive and m | Health and Human Services, Department of / National Institutes of Health | 6/08/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $99,922 | Grant | Trans-NIH Recovery Act Research Support: Liver development in embryos and regeneration in adults are characterized by regulated hepatocyte proliferation. This contrasts with the unregulated hepatocyte proliferation that accompanies many chronic hepatic diseases and hepatocellular carcinoma (HCC) | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $843,744 | Grant | Trans-NIH Recovery Act Research Support: Colonoscopy offers the opportunity for early detection and, even better, true prevention of colorectal cancer, by interrupting the polyp to cancer sequence through polypectomy. Surveillance intervals for patients with polyps are determined by the histolog | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE | $384,336 | Grant | Trans-NIH Recovery Act Research Support: The long-term objective of our parent grant is to determine the molecular mechanisms through which chronic inflammation promotes lung cancer. The asbestos model of lung injury is well established in our laboratory and it serves as a paradigm for inducing | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $80,700 | Grant | Trans-NIH Recovery Act Research Support: The rational design of opioid drugs requires a detailed understanding of the precise interactions between opioid ligand and opioid receptor that underlie ligand selectivity for a particular opioid receptor and that distinguish agonist from antagonist func | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| RESEARCH TRIANGLE INSTITUTE | $603,558 | Grant | Trans-NIH Recovery Act Research Support: The goal of this program is to develop safe neurotransmitter releasers as potential treatments for drug abuse and addiction without the undesirable side effects seen with releaser medications such as Fen-Phen. It is believed that such side effects are in | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF IOWA, THE | $35,664 | Grant | Trans-NIH Recovery Act Research Support: This award is issued in response to Notice OD-09-060, Recovery Act Administrative Supplements Providing Summer Research Experiences for Students and Science Educators. This research application is in response to #RFA-DA-06-004. At the heart of drug and al | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $162,530 | Grant | Trans-NIH Recovery Act Research Support: Information Processing & the Inferior Colliculus. This is a supplement to the grant with the title above. It is intended to accelerate the science (ACC) in that grant by supporting additional personnel and to purchase research equipment (EQ). | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| BARNARD COLLEGE (INC) | $13,300 | Grant | Trans-NIH Recovery Act Research Support: Funding for two undergraduate students during the summer of 2009 | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $217,030 | Grant | Trans-NIH Recovery Act Research Support: Parent Grant: The primary goal of the parent grant, NIDCD 496: Developmental Phonological Disorders, is to identify and validate etiological subtypes of childhood speech disorders of unknown origin. This supplement proposal seeks to identify one or more g | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| MASSACHUSETTS EYE AND EAR INFIRMARY & PHYSICIAN STAFF, INC. | $17,309 | Grant | Trans-NIH Recovery Act Research Support: Pharmacology of Neurotransmitters in hair cell organs which is to explore the roles of glutamate receptors and associated proteins in the regulation of afferent synaptic activity in the cochlea. Specifically she will look for interaction partners for glut | Health and Human Services, Department of / National Institutes of Health | 6/30/2009 |
| DUKE UNIVERSITY | $144,871 | Grant | Trans-NIH Recovery Act Research Support: Nontypable Haemophilus influenzae is an important human pathogen and represents the leading cause of both acute otitis media and otitis media with effusion, conditions associated with deficiencies in language acquisition, speech development, and school pe | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF ROCHESTER | $49,742 | Grant | Trans-NIH Recovery Act Research Support: This summer research experience grant is to provide one undergraduate student and one science educator jobs for the summer learning how to conduct and analyze scientific experiments. | Health and Human Services, Department of / National Institutes of Health | 5/28/2009 |
| HOUSE EAR INSTITUTE INC | $226,408 | Grant | Trans-NIH Recovery Act Research Support: The overall long-term objective of the parent grant is to investigate changes in human peripheral auditory system function throughout the lifespan and to investigate the relationship between these changes and concomitant changes in speech perception. The | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF SOUTH FLORIDA | $78,400 | Grant | Trans-NIH Recovery Act Research Support: The avian inner ear is a dynamic model for studying the growth and development of excitation in auditory and vestibular hair cells. Over the past 15 years this model has produced a number of improtant discoveries, including ion channels, receptors, senso | Health and Human Services, Department of / National Institutes of Health | 8/12/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $154,009 | Grant | Trans-NIH Recovery Act Research Support: Aminoglycoside antibiotics are essential for battling life-threatening bacterial sepsis. Aminoglycosides also cause permanent deafness/balance disorders and nephrotoxicity in more than 120,000 individuals each year in the US, particularly in infants and | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $98,000 | Grant | Trans-NIH Recovery Act Research Support: Whether it be the aroma of our morning coffee or the scent of a lover, the sense of smell is a critical feature of daily life. The long-term objective of our research is to understand how olfactory information is processed in the mammalian brain. To addre | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| HOUSE EAR INSTITUTE INC | $191,566 | Grant | Trans-NIH Recovery Act Research Support: A one-year training period is proposed at the House Ear Institute (HEI) for Dr. Wilkinson in the laboratory of Qian-Jie Fu, Ph.D. The supplement would attach Dr. WilkinsonG??s training to Dr. FuG??s R01 grant on audio processing for cochlear implants (NID | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| OHIO UNIVERSITY | $311,390 | Grant | Trans-NIH Recovery Act Research Support: This award seeks to accelerate progress on three Aims of a current RO1 Mechanisms of singalling in octoconial organs (E. Peterson, PI). The overall goal of the mulit-institution parent award is to characterize stimuli to an otoconial organ, the utricle, | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $183,571 | Grant | Trans-NIH Recovery Act Research Support: This project is an extension of parent grant DC05439 entitled Ion channel function in auditory and vestibular hair cells. For the supplement we propose to extend these studies to examine the role of a class of ion channels genes in hair cells. The hair c | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF MIAMI | $119,998 | Grant | Trans-NIH Recovery Act Research Support: This project will provide support for key personal in my laboratory where we study Molecular genetic bases of Non-syndromic deafness, and to explore our recent new finding that loss-of-function mutations in PRPS1, an important regulator of rates of the pa | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF MARYLAND | $127,230 | Grant | Trans-NIH Recovery Act Research Support: Mammals use several chemosensory systems to detect and encode their chemical environment. How these systems discriminate relevant chemical cues is a major unresolved question. We hypothesize that differences in the stimulus selectivity of different popula | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $173,995 | Grant | Trans-NIH Recovery Act Research Support: Moraxella catarrhalis is a Gram-negative human mucosal pathogen, a significant cause of middle ear infections and sinusitis in infants and children and an important source of exacerbations in adults with lung disease. It is the third leading cause of otit | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $17,748 | Grant | Trans-NIH Recovery Act Research Support: The supplement to R01DC005991 was to increase the pace of scientific discovery on the parent grant. It was also designed to give three undergraduate students an intense exposure to cutting edge research with the hope of allowing them to explore their int | Health and Human Services, Department of / National Institutes of Health | 6/30/2009 |
| GEORGETOWN UNIVERSITY (THE) | $160,163 | Grant | Trans-NIH Recovery Act Research Support: The long range goal of this project is to develop more effecive treatments for remediating acquired disorders of reading (alexias). There are two main foci: the development of the use of eyetracking as an objective assessment tool; and the expansion of t | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE | $187,618 | Grant | Trans-NIH Recovery Act Research Support: Motion sickness, which is defined as nausea, vomiting, disorientation and related symptoms in association with movement of the subject or the visual surround, can be elicited by rotating subjects about an axis, tilted relative to the gravitational vertica | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| STOWERS INSTITUTE FOR MEDICAL RESEARCH | $28,620 | Grant | Trans-NIH Recovery Act Research Support: Summer research experiences for two undergraduate students in health-related scientific research | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| ROCHESTER GENERAL HOSPITAL | $309,776 | Grant | Trans-NIH Recovery Act Research Support: NTHi Immunity in Young Children (Accelerating the Science supplement): Within the scope of the parent study of acute otitis media (AOM), this supplemental project seeks support to accelerate the tempo of scientific research, increase diversity recruitmen | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE OF | $18,306 | Grant | Trans-NIH Recovery Act Research Support: It is currently understood that arterial baroreceptors control sympathetic nervous system tone, while vestibular end organs provide afferent input to a vestibulo-sympathetic reflex that normally augments the compensatory baroreflex. However, the chemical | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| WINIFRED MASTERSON BURKE MEDICAL RESEARCH INSTITUTE, INC, THE | $253,017 | Grant | Trans-NIH Recovery Act Research Support: The funding requested in this supplement has accelerated the tempo of scientific research in our laboratory, enabled job creation and promoted economic development. Dr. Banerjee has continued with great success the studies that were proposed for this ARRA | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| WASHINGTON UNIVERSITY, THE | $168,183 | Grant | Trans-NIH Recovery Act Research Support: The Overall Goal in this collaborative research project is to assess the effectiveness of rTMS in a large number of tinnitus patients and to assess whether there are patient and clinical factors that are predictors of outcome. In the original application | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF ROCHESTER | $151,884 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this Administrative Supplement is to accelerate the pace of scientific discovery on the aims of the parent grant, which examines the specificity and familiality of chemosensory function and eating behavior in autism. Through the suppleme | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| FATHER FLANAGAN'S BOY'S HOME INC | $146,000 | Grant | Trans-NIH Recovery Act Research Support: The goal of this project was to demonstrate the feasibility and effectiveness of conducting research experiments and conducting clinical measurements with cochlear implant (CI) recipients via remote/distance technology. This study evaluated the following | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $586,456 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The larynx is a strategically important organ situated at the crossroads of the upper respiratory and digestive tracts, orchestrating swallowing, breathing, coughing and, in humans, voice. The hallmark of many clinical | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $32,883 | Grant | Trans-NIH Recovery Act Research Support: The primary aim of the proposed research is to develop a miniature microphone diaphragm for hearing aids that achieves second-order directional sensitivity to sound over the frequency range that is important for speech. A hearing aid that can achieve seco | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| TEXAS A&M UNIVERSITY SYSTEM,THE | $355,263 | Grant | Trans-NIH Recovery Act Research Support: The research proposed in this competitive revision application as well as the parent grant application focuses on dentin matrix protein 1 (DMP1) and dentin sialophosphoprotein (DSPP), two non-collagenous extracellular matrix (ECM) proteins that belong to | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| LOUISIANA STATE UNIVERSITY SYSTEM | $173,824 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Tooth eruption requires alveolar bone resorption and bone formation. We have shown that the osteoclastogenesis needed for resorption of alveolar bone in the coronal region of the bony crypt is regulated by expression o | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $114,782 | Grant | Trans-NIH Recovery Act Research Support: The scope of our ongoing research is to understand the mechanisms by which Candida albicans Hsp70 protein (Ssa1 and Saa2p) bind to and mediate uptake of salivary Histatin 5 (Hst 5), with the long-term goal of development of peptide-based alternative thera | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $57,236 | Grant | Trans-NIH Recovery Act Research Support: These supplemental funds will be used to support more in-depth work within the existing project on children affected with craniofacial malformation, hemifacial microsomia (HFM). Measurements of psycho-social and cognitive status in the current study use i | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| UNIVERSITY OF MARYLAND | $51,889 | Grant | Trans-NIH Recovery Act Research Support: We will employ a rat model of inflammatory pain to study interactions between glia, cytokines, and neurons and explore their significance in the central nervous system response to injury and the development of persistent orofacial pain conditions. The ou | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $16,300 | Grant | Trans-NIH Recovery Act Research Support: It is hypothesized that the genomes of bacterial pathogens are comprised of a core gene pool and a flexible gene pool. The stable core gene pool is inherited clonally and is found in virtually every strain of a species. In contrast, the flexible pool cont | Health and Human Services, Department of / National Institutes of Health | 6/02/2009 |
| TEXAS A & M UNIVERSITY SYSTEM HEALTH SCIENCE CENTER RESEARCH | $51,873 | Grant | Trans-NIH Recovery Act Research Support: This award was issued in response to Notice OD-09-060, Recovery Act Administrative Supplements Providing Summer Research Experiences for Students and Science Educators. The parent grant (R01 ED013368) was awarded by NICDR/NIH for research on the Regulati | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |