Listing all stimulus spending by amount, in descending order. Return to National Institutes of Health page
Amount refers to both the amount of stimulus funding going toward the project and the face value of the loan.
| Recipient | Amount | Type | Description | Federal Dept./Agency | Date |
|---|---|---|---|---|---|
| JOHNS HOPKINS UNIVERSITY, THE | $199,311 | Grant | Trans-NIH Recovery Act Research Support: This ARRA was a supplement to my NIH RO1 13899 grant entitled ?Formation of the Drosophila salivary gland? in which we use the Drosophila salivary gland as a simple model system for learning how organs are specified, how they form and how they become spec | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF CONNECTICUT | $213,438 | Grant | Trans-NIH Recovery Act Research Support: Oral thrush (pseudomembranous candidiasis) continues to afflict an unacceptably high percentage of immunocompromised individuals, particularly children. Because the recalcitrant nature of this oral infection, triggered primarily by C. albicans, could be a | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $51,499 | Grant | Trans-NIH Recovery Act Research Support: Fibronectin (FN) and its receptors are important regulatory components in tumor cell survival. We have determined that the carboxyl-terminal heparin-binding domain and alternatively spliced V region of FN are important to this process, since a FN miniprot | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF WASHINGTON | $377,500 | Grant | Trans-NIH Recovery Act Research Support: This proposal is set forth in response to Notice Number: NOT-OD-09-058 and Notice Title: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications under the active Parent 2R010E05109-05A1 entitled 'Key Modulators of Cement | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF MEDICINE AND DENTISTRY OF NJ (INC) | $29,640 | Grant | Trans-NIH Recovery Act Research Support: This grant provided a summer research experience for Juan Crosby in health-related scientific research | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| FORSYTH DENTAL INFIRMARY FOR CHILDREN | $7,292 | Grant | Trans-NIH Recovery Act Research Support: Three specific aims were proposed, as described in the supplemental grant proposal. Aim 1: To determine the effect of the 32 kDa enamelin on the self-assembly behavior of selected native and recombinant amelogenin?s; Aim 2: To characterize the effect of t | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $16,936 | Grant | Trans-NIH Recovery Act Research Support: This grant provided a summer research experiences for two college students in health-related scientific research. UAB is one of America's premier research universities, ranking among the top 20 in funding from the National Institutes of Health and earnin | Health and Human Services, Department of / National Institutes of Health | 6/02/2009 |
| TRUSTEES OF TUFTS COLLEGE INC | $364,775 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this administrative supplement application made under the ARRA Act is to request funds to greatly accelerate the characterization of human embryonic stem cell- (hESC) derived cell lines with properties of mesenchymal progenitor cells (MPCs) | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $99,745 | Grant | Trans-NIH Recovery Act Research Support: The objective of this application is to understand osteogenic mechanisms of stem cells from human exfoliated deciduous teeth (SHED) as a basis for the development of therapeutic technologies for repairing orofacial bone defects. Autologous grafts from lon | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO ,THE | $105,331 | Grant | Trans-NIH Recovery Act Research Support: One of the more subtle complications of diabetes mellitus is a decrease in the patient's quality of life due to tooth loss and compromised function. While implant therapy has shown promise in patients with well- managed diabetes, questions remain as to th | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF PITTSBURGH THE | $67,580 | Grant | Trans-NIH Recovery Act Research Support: This award provides funds to enable us to purchase equipment that is critical to our studies on the underlying mechanism of dental pain. A critical component of these studies is establishing a causal link between changes in voltage-gated Na+ channel subu | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| TEXAS A & M UNIVERSITY SYSTEM HEALTH SCIENCE CENTER RESEARCH | $14,650 | Grant | Trans-NIH Recovery Act Research Support: Tooth development requires the precise spatial and temporal coordination of programs for cell growth, differentiation, and mineralization. In a search for genes required for normal tooth morphogenesis we have studied Dentin matrix protein1 (DMP1), a non- | Health and Human Services, Department of / National Institutes of Health | 6/02/2009 |
| TEXAS A & M UNIVERSITY SYSTEM HEALTH SCIENCE CENTER RESEARCH | $14,650 | Grant | Trans-NIH Recovery Act Research Support: The parent greant (R01 DE019471) was awarded by NICDR/NIH for research on the Signaling Mechanisms in Early Tooth Development. This supplement provides short-term research experience for two college graduates during the summer preceding their entry into | Health and Human Services, Department of / National Institutes of Health | 6/02/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $21,485 | Grant | Trans-NIH Recovery Act Research Support: This project focuses on the molecular mechanisms through which aldosterone stimulates Na transport in target epithelia. During the last grant period we identified serum- and glucocorticoid-induced kinase-1 (SGK1) as an aldosterone-induced early response g | Health and Human Services, Department of / National Institutes of Health | 8/29/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $149,700 | Grant | Trans-NIH Recovery Act Research Support: Ischemic injury is at the heart of approximately 50% of all cases of acute renal failure. One hallmark of ischemia is a severe drop in cellular ATP levels, which promotes numerous changes in cellular functions, including broad suppression of transcription | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| BRENTWOOD BIOMEDICAL RESEARCH INSTITUTE, INC. | $80,873 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement requests funds to hire a Staff Research Associate (SRA) and to replace an unserviceable ultracentrifuge. Helicobacter pylori, a gram-negative neutralophile, is the only bacteria known to colonize and grow in the normal human | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $100,000 | Grant | Trans-NIH Recovery Act Research Support: Hereditary hemochromatosis (HH) is the most common inherited disorder in people of Northern European descent. Over 83% of the cases of HH result from a single mutation of a Cys to Tyr in the HH protein, HFE. This mutation causes a recessive disease result | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| THE WASHINGTON UNIVERSITY | $37,495 | Grant | Trans-NIH Recovery Act Research Support: Disturbances in hepatic fatty acid (FA) metabolism and triglyceride storage promote hepatic steatosis, and are considered key metabolic precursors to nonalcoholic fatty liver disease (NAFLD). This application will examine the regulation of hepatic FA meta | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| MAYO CLINIC | $99,348 | Grant | Trans-NIH Recovery Act Research Support: Portal hypertension and its complications account for much of the morbidity and mortality associated with cirrhosis. The Long-Term Goal of our lab is to understand the molecular control mechanisms of portal hypertension. Sinusoidal vasoconstriction is an | Health and Human Services, Department of / National Institutes of Health | 8/06/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $91,400 | Grant | Trans-NIH Recovery Act Research Support: Smooth muscle cells (SMCs) in different tissues express distinct groups of proteins that give each tissue unique physiological properties. However, few studies have comprehensively defined the transcription regulatory networks that are responsible for the | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| CHILDREN'S HOSPITAL CORPORATION, THE | $26,286 | Grant | Trans-NIH Recovery Act Research Support: The mammalian small intestine is lined by a highly differentiated epithelium comprised of specialized absorptive and secretory cell lineages that display a wide-ranging, yet tightly regulated diversity along the cephalo-caudal axis, resulting in an exquis | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| UNIVERSITY OF PITTSBURGH THE | $98,850 | Grant | Trans-NIH Recovery Act Research Support: The initial phase of the North American Pancreatitis Study 2 (NAPS2) was a 20-site, multicenter molecular epidemiology study designed to determine the regional prevalence of major pancreatic diseases; to determine the underlying genetic variations and imm | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF MARYLAND | $44,560 | Grant | Trans-NIH Recovery Act Research Support: The transcriptional activator TonEBP is essential for the development and function of the renal medulla. Activated by hypertonicity (hyperosmotic salinity), TonEBP is a key regulator for the urinary concentration via stimulating transcription of aquaporin | Health and Human Services, Department of / National Institutes of Health | 8/29/2009 |
| CHILDRENS HOSPITAL OF PHILADELPHIA | $8,111 | Grant | Trans-NIH Recovery Act Research Support: Our studies address a critical problem in hemoglobin (Hb) biology: how inherently unstable globin protein subunits are folded and maintained during normal and pathological erythropoiesis. We discovered alpha hemoglobin stabilizing protein (AHSP), an eryth | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC. | $100,000 | Grant | Trans-NIH Recovery Act Research Support: One major goal of this administrative supplement is to support a Senior Research Associate who will significantly accelerate the tempo of scientific research on Specific Aims 1 and 2 of our grant entitled A mouse model of acrodermatitis enteropathica. Thi | Health and Human Services, Department of / National Institutes of Health | 8/24/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $30,096 | Grant | Trans-NIH Recovery Act Research Support: The goal of this award is to introduce students to scientific research experiences and to stimulate the economy by providing summer employment opportunities to college students. | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $86,647 | Grant | Trans-NIH Recovery Act Research Support: During the last project period, our efforts led to the discovery of several small molecule iron transport inhibitors. One of these compounds, ferristatin, blocks both transferrin-mediated and DMT1-mediated iron transport. Ferristatin blocks uptake of tra | Health and Human Services, Department of / National Institutes of Health | 8/21/2009 |
| UNIVERSITY OF CINCINNATI | $141,300 | Grant | Trans-NIH Recovery Act Research Support: IgA nephropathy (IgAN) is the most common form of glomerulonephritis, an inflammatory disease of the kidney. IgAN is characterized by deposition of lgA1 antibodies in the glomerular mesangium of the kidney, followed by infiltration of inflammatory immune | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF ILLINOIS | $98,671 | Grant | Trans-NIH Recovery Act Research Support: This award is to be used improve both events ascertainment collection and retention effors for the Hispanic Chronic Renal Insufficiency Cohort (HCRIC) Study. The HCRIC Study is based at the University of Illinois at Chicago (UIC) and is a R01 funded anci | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $363,186 | Grant | Trans-NIH Recovery Act Research Support: Title:Receptor Interaction with GTP-Regulatory Proteins. Aims of the funded parent grant: 1. Define function for the SWIM and RING domains of MEKK1 for binding and ubiquitination of c-Jun, JunB, c-Raf and other regulatory proteins. 2. Genomic analysis of | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF CHICAGO, THE | $341,835 | Grant | Trans-NIH Recovery Act Research Support: The experiments in this proposal are functional and structural studies using electrophysiological, fluorescence spectroscopy and protein and chemical modification done simultaneously in voltage dependent proteins such as Na and K channels. The emphasis is | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $192,897 | Grant | Trans-NIH Recovery Act Research Support: The award supports studies on the structure and function of human drug metabolizing enzymes that determine the clearance for many therapeutic drugs. X-ray crystallography is employed to characterize the structures of these P450 monooxygenases in complex w | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $219,719 | Grant | Trans-NIH Recovery Act Research Support: This award is a supplement 3R01GM033143-22S1 ARRA, which is entitled Long Range DNA Interactions in Mu and Bacterial DNA. The start date is 09/30/2009 and this project will end on 08/31/2011. The full amount to be distributed over 2 years is $219,719. | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| PENNSYLVANIA STATE UNIVERSITY, THE | $30,656 | Grant | Trans-NIH Recovery Act Research Support: Hepatocellular carcinoma (HCC) is one of the most common causes of cancer death and is on the rise in the United States. Preventative strategies are highly important in reducing the incidence and death from HCC. HCC is a slow process that occurs in the se | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| PENNSYLVANIA STATE UNIVERSITY, THE | $100,000 | Grant | Trans-NIH Recovery Act Research Support: Hepatocellular carcinoma (HCC) is one of the most common causes of cancer death and is on the rise in the United States. Preventative strategies are highly important in reducing the incidence and death from HCC. HCC is a slow process that occurs in the se | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE INC | $66,390 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of our program is to better understand the regulation of cerebrovascular function and structure, in order to identify new targets and develop new strategies for prevention and treatment of stroke in diabetes. The central hypothesis of | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $99,876 | Grant | Trans-NIH Recovery Act Research Support: Sensory nerves in the esophagus are essential for the regulation of its physiological function. Sensory nerves also mediate conscious sensations (heartburn, pain) and defensive reflexes from the esophagus. Perverted function of esophageal sensory nerves m | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| SCOTT & WHITE MEMORIAL HOSPITL | $9,428 | Grant | Trans-NIH Recovery Act Research Support: This grant was to provide a summer research experience for one undergraduate student in health-related scientific research. The student will be exposed and trained in all aspects of the current research project including specific study design, subject re | Health and Human Services, Department of / National Institutes of Health | 6/23/2009 |
| PENNSYLVANIA STATE UNIVERSITY, THE | $42,594 | Grant | Trans-NIH Recovery Act Research Support: The overall objective is to determine the mechanism(s) mediating the increased cellular damage and the impaired subsequent recovery in the diabetic brain following a stroke. The underlying hypothesis of this proposal is that the greater damage and impaire | Health and Human Services, Department of / National Institutes of Health | 6/23/2009 |
| THE VANDERBILT UNIVERSITY | $49,926 | Grant | Trans-NIH Recovery Act Research Support: The investigations currently funded by R01 DK075555 are focused on elucidating the function of the brush border cytoskeleton and its associated motor proteins in the normal physiology and pathophysiology of the enterocyte. As the primary site of nutrient | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| PALO ALTO MEDICAL FOUNDATION FOR HEALTH CARE, RESEARCH AND EDUCATION (INC) | $557,936 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The revision to the parent grant, 5 R01 DK081371-02: Identifying Disparities in Type 2 Diabetes Among Asian Americans: The Pan Asian Cohort Study, is in response to NOT-OD-09-058: NIH Announces the Availability of Reco | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| BAYLOR COLLEGE OF MEDICINE | $173,920 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of this BRP project is to engineer hematopoietic bone ex vivo to provide synthetic organ based therapies for disorders of both bone and hematopoiesis. Our overarching hypotheses are that the steps that lead to bone formation and the est | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $207,374 | Grant | Trans-NIH Recovery Act Research Support: The primary objective for this funding is to speed up analyses and develop an improved understanding of the organophosphate (OP) toxicity pathway and the role of paraoxonase 1 (PON1) genotypes and enzymatic activity in children with high exposure to pesti | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $337,815 | Grant | Trans-NIH Recovery Act Research Support: ARRA - Adducts as Quantitative Markers of Butadiene Mutagenesis - Administrative Supplement This administrative supplement will clearly accelerate the pace of research on mechanisms of BD carcinogenesis and mutagenesis. It has been designed to provide a c | Health and Human Services, Department of / National Institutes of Health | 9/02/2009 |
| UNIVERSITY OF CINCINNATI | $151,528 | Grant | Trans-NIH Recovery Act Research Support: The importance of somatic mutation in the genesis of cancer and other diseases is undisputed. However, the extent to which loss of heterozygosity (LOH), as a consequence of mitotic recombination, contributes to the frequency of spontaneous mutation has be | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $371,436 | Grant | Trans-NIH Recovery Act Research Support: Our current grant, 5R01ES15829-2 G?Measuring Human Exposure to PBDEsG? is assessing PBDEs at multiple steps of the exposure-response continuum. We are characterizing potential PBDE sources (consumer products), key microenvironments (dust from home, workp | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE/CWRU | $331,022 | Grant | Trans-NIH Recovery Act Research Support: Choroidal neovascularization (CNV) is the major cause of severe vision loss in patients with age-related macular degeneration (AMD). The neovascularization originates from the choriocapillaris and grows through Bruch's membrane, into the sub-retinal pigme | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON | $197,822 | Grant | Trans-NIH Recovery Act Research Support: In the visual system, the information transmitted from the retina is analyzed and transformed by the visual cortex at multiple stages to construct an internal representation of the environment. It has long been suggested that the visual cortex is a passiv | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH | $143,947 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this grant was to provide a summer research experience for 1 science educator in health-related scientific reearch. | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| UNIVERSITY OF FLORIDA | $383,257 | Grant | Trans-NIH Recovery Act Research Support: We can show that gamma-secretase is a potent regulator of vascular permeability and angiogenesis both in vitro and in vivo and that this effect is dependent on the targeted translocation of the C-terminal domain of VEGFR1. Our previous studies have chara | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| UNIVERSITY OF WASHINGTON | $28,435 | Grant | Trans-NIH Recovery Act Research Support: This supplement will accelerate progress on all three Aims of my funded NEI grant, Role of cerebellar parallel fibers in saccade accuracy, R01 EY018585, Farrel R Robinson, P.I. Aims 1 and 2 require quantitative analysis of eye movements and single neuron | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| CORNELL UNIVERSITY, INC | $198,747 | Grant | Trans-NIH Recovery Act Research Support: Our long-term objective is to identify how protein conformation plays a role in various diseases. Our specific aims are to compute the 3D structures of proteins, protein-protein and protein-nucleic acid complexes, and the folding pathways leading to these | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF UTAH, THE | $276,192 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): This is a competitive revision proposal in response to Notice Number NOT-OD-09-058. The Notice Title is: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. The long-term objecti | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $267,664 | Grant | Trans-NIH Recovery Act Research Support: Funds for one postdoctoral associate to characterize a gene and encoded enzyme proposed to generate the dichlorinated differentiation factor Dif1 in the cellular slime mold Dictyostelium discoideum. Studies will involve purification of the enzyme and assa | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY | $418,500 | Grant | Trans-NIH Recovery Act Research Support: The Administrative Supplement to GM021342 ?Energetics of Channel-Bilayer Interactions? will enhance the scope of the project, as it will allow for ?higher-throughput? studies on the bilayer-modifying effects of small amphiphiles, such as drugs used clinic | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF WASHINGTON | $244,098 | Grant | Trans-NIH Recovery Act Research Support: The dynamical behavior of proteins will be investigated, using time-resolved Raman and infrared spectroscopies as probes of structure in real time. Laser temperature-jump techniques will be applied to the protein folding problem in order to characterize t | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $266,510 | Grant | Trans-NIH Recovery Act Research Support: Our laboratory uses the biflagellated green alga Chlamydomonas reinhardtii as a model system to study cilium-generated signaling and ciliary/flagellar shortening. During the Chlamydomonas mating reaction, adhesion receptors (agglutinins) on the flagella | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF WASHINGTON | $255,519 | Grant | Trans-NIH Recovery Act Research Support: The overall aim of the proposal is to understand the contribution of transcriptional regulation of gene expression to the regulation of metabolism, particularly as it relates to alcohol metabolism, diabetes, and disorders such as metabolic syndrome. The g | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| BROWN UNIVERSITY IN PROVIDENCE IN STATE OF RI AND PROVIDENCE PLANTATIONS | $363,740 | Grant | Trans-NIH Recovery Act Research Support: The four-way DNA junction known as the Holliday junction (HJ) figures prominently in DNA recombination, replication and repair; it is the central intermediate in both homologous and site-specific recombination, where genetic, biochemical and structural st | Health and Human Services, Department of / National Institutes of Health | 9/08/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $77,735 | Grant | Trans-NIH Recovery Act Research Support: The overall aim of this research is to investigate the mechanisms by which the CCCH zinc finger protein muscleblind (MBNL), a developmentally programmed regulator of alternative pre-mRNA splicing, recognizes specific regulatory sites in single stranded RN | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $204,165 | Grant | Trans-NIH Recovery Act Research Support: P2Y-Purinergic Receptors - ARRA Nucleotides and nucleotide sugars act as extracellular signaling molecules to regulate a remarkably broad array of physiological responses ranging from neurotransmission to epithelial ion transport to platelet aggregation. | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| CASE WESTERN RESERVE UNIVERSITY | $136,234 | Grant | Trans-NIH Recovery Act Research Support: Mg chemistry is unique among biological cations, and cells possess novel mechanisms for regulating Mg2+ and facilitating its passage through membranes. This proposal focuses on the CorA Mg2+ transporter, the primary Mg2+ uptake system for most Eubacteria | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF UTAH, THE | $68,242 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The long term goal of this project is to elucidate the role of protein flexibility in determining the energetic and functional aspects of protein-protein interactions, particularly in the context of serine proteases an | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $252,468 | Grant | Trans-NIH Recovery Act Research Support: Mitotic regulation is fundamentally important to all eukaryotic life and has medical significance as mitotic defects can lead to aneuploidy and cancer. Mitosis is regulated by a complex interplay of conserved protein kinases but there is a limited underst | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $176,539 | Grant | Trans-NIH Recovery Act Research Support: The specific aims of the parental grant are to create novel switches while exploring the molecular basis of protein DNA recognition and allosteric signaling as it relates to gene regulation. We proposed to approach this problem by using a directed evoluti | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| NORTH CAROLINA STATE UNIVERSITY | $438,949 | Grant | Trans-NIH Recovery Act Research Support: The parent grant proposes a detailed systems genetics analysis of variation for complex traits in Drosophila, using the Drosophila Genetic Reference Panel (DGRP) of 192 inbred D. melanogaster lines with complete DNA sequence data. These lines and genome w | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| DUKE UNIVERSITY | $70,900 | Grant | Trans-NIH Recovery Act Research Support: Supplemental funds ($90,620) are requested to accelerate the pace of this award. The supplemental funds requested do not involve a change in scope of the project, but will accelerate the pace of our studies by allowing us to work more efficiently. They ar | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $218,986 | Grant | Trans-NIH Recovery Act Research Support: Cell migration is a major driving force in embryonic development, wound healing, and tumor metastasis. Therefore understanding the molecular mechanisms that control whether, when, and where cells move is significant for human health and disease. My labora | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK INC | $192,780 | Grant | Trans-NIH Recovery Act Research Support: The goal of this supplement was to fund the salary of one-predoctoral fellow to collect and analyze additional data sets (4D ultrasound and MRI) to test the hypothesis that strain measures computed with 4D ultrasound and optical flow can yield clinically | Health and Human Services, Department of / National Institutes of Health | 7/31/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $272,986 | Grant | Trans-NIH Recovery Act Research Support: Aim 1 will use PA segments isolated from chronically hypoxic calves and mice and in vitro pulmonary artery vascular cells isolated from the neonatal calf to evaluate production of reactive oxygen species and expression and activity of EC-SOD. Aim 2 will u | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF WASHINGTON | $257,006 | Grant | Trans-NIH Recovery Act Research Support: The central hypothesis of the parent grant is that mechanical ventilation modulates the acute transcriptional response to pathogen-associated molecular patterns in epithelial cells via activation of activator protein-1 (AP-1) heterodimeric transcription f | Health and Human Services, Department of / National Institutes of Health | 8/12/2009 |
| LUCID INFORMATION DEVELOPMENT SOLUTIONS, LLC | $99,960 | Contract | : Provide technical writing support to review and process challenge grants. | Health and Human Services, Department of / National Institutes of Health | 7/10/2009 |
| NEKOLA, MARY V | $51,000 | Contract | : RECOVERY SERVICES for SRB/NIAin identifying reviewersfor applications submitted to NIA for review and preparation of summary statements. | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| AMNIS CORPORATION | $419,000 | Contract | : Amnis ImageStreamX System | Health and Human Services, Department of / National Institutes of Health | 7/29/2009 |
| SLATER MD, STANLEY | $156,000 | Contract | : Recovery Scientific Programatic Support | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| SOCIAL & SCIENTIFIC SYSTEMS, INC. | $12,962,657 | Contract | : Technical support and administrative/management services: Task Order 6, Antiviral and Immune Plasma Infrastructure Development | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| RANGER GROUP LLC, THE | $3,857,474 | Contract | : Recovery Act -- Repair & Upgrade Switchgear -- Building 29 | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $103,812 | Grant | Trans-NIH Recovery Act Research Support: Function of MEKK3 and its osmosensing scaffold protein AARA. Supplementary funds for NIH grant GM68820 were requested to specifically accelerate the tempo of the discovery process directly related to aims of the parent grant. To increase tempo, we reques | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $208,005 | Grant | Trans-NIH Recovery Act Research Support: Given the lack of information regarding short and long term consequences of skin grafting with respect to revascularization and reinnervation of the grafted skin, the primary objective of this proposal is to test the hypothesis that autonomic and non-auto | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $96,873 | Grant | Trans-NIH Recovery Act Research Support: This proposal outlines new types of experiments that probe three basic aspects of membrane dynamics: the mechanism of vesicle fusion (Aim 1), the lateral association of certain lipids and membrane anchored proteins (Aim 2), and high precision interferomet | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF TEXAS AT AUSTIN | $125,000 | Grant | Trans-NIH Recovery Act Research Support: Nitric oxide (NO) is a small reactive radical that plays a significant role in cancer biology. Aberrant production of NO and other oxidants is found in various types of tumors, including breast cancer, and also at sites of chronic inflammation, which have | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| TEXAS A & M RESEARCH FOUNDATION | $109,563 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of our research is to understand the role that plays glycosylation in regulating cell interactions during animal development. Mammalian sialylation has become the focus of intensive investigation because of its involvement in important | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| NORTHWESTERN UNIVERSITY | $141,290 | Grant | Trans-NIH Recovery Act Research Support: This award is issued in response to Notice OD-09-060, Recovery Act Administrative Supplements Providing Summer Research Experiences for Students and Science Educators. DESCRIPTION (provided by applicant): Epithelial cells are polarized into distinct apica | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | $130,316 | Grant | Trans-NIH Recovery Act Research Support: Regulated exocytosis of secretory membrane vesicles proceeds via recruitment of the vesicles to the plasma membrane at specific sites conducive for exocytosis, followed by staged fusion into the plasma membrane. Generalized defects in regulated exocytosis | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $139,005 | Grant | Trans-NIH Recovery Act Research Support: Drosophila is one of a handful of model organisms used extensively in biomedical research. Importantly 60% of human disease genes are conserved in the fly. Genetic analysis in Drosophila has focused primarily on a whole organism approach but cell lines ha | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF MARYLAND | $236,484 | Grant | Trans-NIH Recovery Act Research Support: The primary purpose of this Administrative Supplement is to develop a scanning optical system capable of providing high sensitivity 2-D protein mapping from microfluidic protein profiling chips, and to optimize the microfluidic system in the context of th | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $72,430 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this award is to hire one person to conduct yeast 2 hybrid screens to identify novel interactors with SPE-11, KCA-1 and FZY-1. The results of this work will be published and provide information on the basic mechanisms of female meiosis. | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF TEXAS M D ANDERSON | $203,365 | Grant | Trans-NIH Recovery Act Research Support: G protein-coupled receptors (GPCRs) constitute a large family of cell surface receptors, and play an important role in regulating cell survival and proliferation. They transduce environmental signals across the cytoplasm membrane through their ability to | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| BAYLOR COLLEGE OF MEDICINE | $198,124 | Grant | Trans-NIH Recovery Act Research Support: EMAN is a software suite for two and three dimensional image processing of transmission electron microscopy data. Its original design was specifically to perform the compuations required for a technique known as single particle reconstruction. This techni | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $318,019 | Grant | Trans-NIH Recovery Act Research Support: While the parent R01 deals with the discovery and development of a collection of metal-mediated coupling reactions for the synthesis of a subset of organic architectures that are of great interest in medicinal chemistry, the funds secured from this ARRA-b | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| UNIVERSITY OF PITTSBURGH THE | $355,013 | Grant | Trans-NIH Recovery Act Research Support: Proper regulation of NF-KB transcription factors is critical for the mounting of immune responses to pathogens and for the normal homeostasis of the immune system. In this light, it is important to know how NF-KB family transcription factors are controlle | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | $262,759 | Grant | Trans-NIH Recovery Act Research Support: Nucleotide Excision Repair (NER) is a versatile DNA repair pathway involved in the removal of diverse lesions, including those formed by UV light, from DNA. The importance of NER is underscored by the fact that the cancer-prone inherited disorder xeroderm | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| WASHINGTON UNIVERSITY, THE | $259,777 | Grant | Trans-NIH Recovery Act Research Support: Evolution within coding and noncoding sequences is markedly different. Most proteins are highly conserved, even between distantly related species such as yeast and human. In contrast, cis-regulatory sequences rarely if ever remain conserved between distan | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $202,813 | Grant | Trans-NIH Recovery Act Research Support: Posttranslational histone modifications play important roles in regulating chromatin structure and function. In my RO1 GM081489 grant, we propose to thoroughly characterize the H2A deubiquitinase Ubp-M, with goals of determining the roles and elucidating | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $220,357 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this NIH supplement is to provide specialized equipment and technology to improve and facilitate synthetic genetic studies on Maf1, as described under aim II of the parent grant. The goal of this aim is to determine the nuclear events lead | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $656,078 | Grant | Trans-NIH Recovery Act Research Support: Confined proteins (in synthetic matrices, e.g. sol-gels) as a class of materials have significant potential utility for a broad range of biomedical and biotechnology applications. In most situations, long-term protein stability with either retention or en | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| BECKMAN COULTER, INC. | $105,204 | Contract | : Purchase of BIOMEK NXP Multi-Channel Automation Workstation and related BIOMEK system components | Health and Human Services, Department of / National Institutes of Health | 8/27/2009 |
| DJD CONSULTING | $24,000 | Contract | : Technical Review of Assurance Documents | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| RANGER GROUP LLC, THE | $4,858,166 | Contract | : Recovery Act -- Repair & Upgrade Switchgear -- Building 38A | Health and Human Services, Department of / National Institutes of Health | 7/24/2009 |
| RANGER GROUP LLC, THE | $3,919,910 | Contract | : Recovery Act -- Repair & Upgrade Switchgear -- Building 29A | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| CORNELL UNIVERSITY, INC | $110,785 | Grant | Trans-NIH Recovery Act Research Support: Studies supported by GM47458 have been directed toward understanding the roles played by the small GTPase Cdc42 in cell growth and differentiation. We have begun to examine the importance of Cdc42 in these cellular processes and in developmental events b | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $51,326 | Grant | Trans-NIH Recovery Act Research Support: This research will extend our understanding of the function and regulation of the Aurora kinase complex, which is a critical target for cancer therapeutics. | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $59,950 | Grant | Trans-NIH Recovery Act Research Support: Supplemental funding is requested to enhance our ability to image live epithelial cysts growing in 3D Matrigel cultures (existing Aim 1); to extend our ongoing screen for genes involved in tight junction formation and apicallbasal polarization of epitheli | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF UTAH, THE | $397,047 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Notice Number (NOT-OD-09-058) NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications Natural products are still the majority of therapeutic agents. However, they suffer from a diffic | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| TECHNICAL RESOURCES INC | $1,093,005 | Contract | : RECOVERY - ACTNOW Clinical Trials Support provided under the CTEP Drug Development Support for added protocols, including expedited timeframes for regulatory reviews, IND processing, and increased AR reporting. | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| DUKE UNIVERSITY | $49,900 | Grant | Trans-NIH Recovery Act Research Support: The application for administrative supplement is to request funds to purchase an imaging system to accelerate the tempo of the research proposed in the parent grant R01 GM084337-01A2, Small Molecules that Regulate Proteasome Activity. The overall goal of | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $185,716 | Grant | Trans-NIH Recovery Act Research Support: Funding is being requested for additional tasks within the scope of the parent grant. Under the Proposed Task 1, we will extend specific aim 1 to incorporate epigenomic marks as a potential mediator of expression divergence among paralogs. Under the Propo | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $81,611 | Grant | Trans-NIH Recovery Act Research Support: This award provided a Supplement for my NIH RO1, entitled !Cell adhesion, signal transduction and cytoskeletal regulation in Drosophila!. It allowed us to obtain key equipment that will enhance our ability to assess protein dynamics in vivo, abilities th | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | $76,716 | Grant | Trans-NIH Recovery Act Research Support: The goal of this project will be to continue studies of the structure and function of lipid rafts: ordered sphingolipid and cholesterol-rich membrane domains found in mammalian and other eukaryotic cells. Among other functions, rafts are implicated in sor | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $98,178 | Grant | Trans-NIH Recovery Act Research Support: This proposal constitutes a request for a supplement to GM-49076 for a highly focused five-month effort to develop an unanticipated discovery made under the grant. The discovery involved a serendipitouos swap of two peripheral amino acids in peptides tha | Health and Human Services, Department of / National Institutes of Health | 6/19/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $41,000 | Grant | Trans-NIH Recovery Act Research Support: NIH Grant R01GM049975 supports a program in which chemical strategies and tools are developed and deployed to elucidate the molecular mechanisms underlying carbohydrate function. The current focus is on probing the role of the lectin DC-SIGN, which mediat | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF CHICAGO, THE | $245,677 | Grant | Trans-NIH Recovery Act Research Support: Homologous recombination plays a critical role in reductional segregation of chromosomes in meiosis. Meiotic recombination is initiated by the programmed induction of DNA double strand breaks (DSBs) and involves a mechanism related to recombinational repa | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $473,266 | Grant | Trans-NIH Recovery Act Research Support: This project is being supported with funds from the American Recovery and Reinvestment Act, which may involve a reduction in the research aims and scope. If necessary, a revised abstract will be posted soon and this notice removed. DESCRIPTION (provided | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $269,294 | Grant | Trans-NIH Recovery Act Research Support: The major goals of this project are to elucidate the function and regulation of protein phosphorylation in the control of cell growth, differentiation, survival, and metabolism in response to various growth factors. We will particularly focus on the mamma | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $30,618 | Grant | Trans-NIH Recovery Act Research Support: Controlling transcription termination upstream of a coding region is a common strategy to regulate gene expression in bacteria, including many with importance to human health. Such control mechanisms are collectively termed attenuation and antitermination | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY | $111,686 | Grant | Trans-NIH Recovery Act Research Support: With the aid of this administrative supplement mechanistic studies of coupling reactions of alkyl electrophiles and in particular investigations of stereoselective cross-coupling processes of alkyl electrophiles will be pursued. Enantioselective react | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $167,247 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Hsp70 (heat shock 70 kDa) chaperone proteins are central to protein folding, refolding, and trafficking in organisms ranging from Archae to Homo Sapiens, both at normal and at stressed cellular conditions. Hsp70's (re) | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| OHIO STATE UNIVERSITY, THE | $228,511 | Grant | Trans-NIH Recovery Act Research Support: The S box system is a novel global regulatory mechanism for control of genes involved in methionine metabolism in Gram-positive bacteria. Genes in the S box family contain a complex set of conserved primary sequence and structural elements upstream of the | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $25,000 | Grant | Trans-NIH Recovery Act Research Support: Programmed cell death in higher eukaryotes provides a mechanism whereby un-needed cells are recycled to benefit the organism. This is particularly important during development and in maintaining tissue homeostasis. Programmed cell death pathways also prov | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| FRED HUTCHINSON CANCER RESEARCH CENTER | $161,334 | Grant | Trans-NIH Recovery Act Research Support: The flawless execution of cell division is essential to the generation and survival of all organisms. During every cell cycle, chromosomes must be accurately partitioned to daughter cells to prevent genomic instability and aneuploidy, a hallmark of all t | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $166,157 | Grant | Trans-NIH Recovery Act Research Support: Protein synthesis is a fundamental process in all living organisms. During the elongation phase of protein synthesis, the ribosome accurately selects the aminoacyl-tRNA corresponding to the mRNA codon. The long-term objective of this proposal is to study | Health and Human Services, Department of / National Institutes of Health | 9/08/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $316,417 | Grant | Trans-NIH Recovery Act Research Support: DNA replication must occur with extraordinary accuracy to permit proper organismal development and to maintain cellular homeostasis. Inevitably, DNA damage occurs due to intrinsic and exogenous factors such as irradiation and chemical exposure. DNA damage | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| UNIVERSITY OF TEXAS AT AUSTIN | $100,000 | Grant | Trans-NIH Recovery Act Research Support: Bioreductive aziridinylbenzoquinones, one of the most potent classes of chemotherapeutic drugs, are alkylating agents that bind covalently to DNA. It is recognized that the basis for the activity of many anti-cancer agents is related to their ability to m | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA AT RIVERSIDE | $102,818 | Grant | Trans-NIH Recovery Act Research Support: Normal cellular function is dependent on the ability of environmental signals to elicit distinct responses through activation of specific cell surface receptors, and yet these signals often converge on the same members of the MAPK family. How can cells ma | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| THE WASHINGTON UNIVERSITY | $10,192 | Grant | Trans-NIH Recovery Act Research Support: Sepsis is the leading cause of death in intensive care units in the United States, with up to 210,000 people dying from the disease annually. Gut epithelial apoptosis is elevated in both animal models and human autopsy studies of sepsis. We have previousl | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $199,678 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement will accelerate the pace of research in Aim 1 of GM66492, in which the goal is to understand how two small molecules, TAME (tosyl arginine methyl ester)and cyclinal, inhibit APC (anaphase promoting complex) -dependent proteo | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $302,198 | Grant | Trans-NIH Recovery Act Research Support: Elongation is the longest part of transcription cycle during which RNA polymerase movement along the template is hindered by many roadblocks DNA-bound proteins, DNA lesions, termination signals, etc. Factors that allow RNA polymerase to bypass these barri | Health and Human Services, Department of / National Institutes of Health | 9/08/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $212,782 | Grant | Trans-NIH Recovery Act Research Support: Aggression is a complex behavior expressed in many different social contexts. Often abused, yet essential for the survival of organisms, little is known of the biological roots of this behavior. While model systems may not duplicate aggression in all of i | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF TEXAS M D ANDERSON | $115,500 | Grant | Trans-NIH Recovery Act Research Support: The Gcn5 histone acetyltransferase (HAT) is implicated in gene activation in organisms from yeast to humans. Although the structure of Gcn5 and the components of Gcn5-containing complexes (e.g. STAGA/TFTC) are well defined, the functions of Gcn5 in mammal | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| THE VANDERBILT UNIVERSITY | $100,700 | Grant | Trans-NIH Recovery Act Research Support: Correct regulation of gene expression requires that a complex set of biochemical events occur with precise timing and sequence. In recent years, it has become evident that one way in which these event are coordinated is by close interactions between the t | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| TRUSTEES OF TUFTS COLLEGE INC | $89,169 | Grant | Trans-NIH Recovery Act Research Support: During development, cell fates are established by signals that emanate from specialized organizer regions. How these signals direct cells to differentiate migrate, and alter their shape during development is a fundamental yet poorly understood question. T | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $130,321 | Grant | Trans-NIH Recovery Act Research Support: This proposal describes the development of general and highly selective Pd-catalyzed methods for converting unactivated arene and alkane C-H bonds to new functional groups X, where X = acetate, ether, amine, halide, cyanide, arene, alkene, or alkyne. Thes | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF WASHINGTON | $126,779 | Grant | Trans-NIH Recovery Act Research Support: This application is for a Recovery Act Administrative Supplement to a current R01 award. The initial and ongoing goals follow.The ability to regenerate structures and biological function would be of considerable value to a large number of patients. For m | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| WORCESTER POLYTECHNIC INSTITUTE | $175,226 | Grant | Trans-NIH Recovery Act Research Support: The award was made to speed up production of a complete polarizable force field for proteins. This will permit more accurate calculations of protein structures and protein-ligand binding energies. The results are expected to be of positive value in biomed | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF IOWA, THE | $207,560 | Grant | Trans-NIH Recovery Act Research Support: Abstract RGS (Regulator of G protein Signaling) proteins represent a novel protein family believed to function as GTPase-activating proteins (GAPs) for heterotrimeric G protein subunits, thereby negatively regulating the duration and intensity of G prote | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $193,499 | Grant | Trans-NIH Recovery Act Research Support: Phosphoinositide metabolic pathways regulate a vast array of cellular functions, including signal transduction, cell growth and division, cytoskeletal assembly, and membrane trafficking. PI4P is the precursor in the biosynthesis of two of the most import | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $265,691 | Grant | Trans-NIH Recovery Act Research Support: The overall purpose of this supplement award is to accelerate the tempo of research, to retain jobs, and to help create jobs. All the goals have been achieved. With this award, we were able to speed up our research on the role of a very important gene, ca | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| OLD DOMINION UNIVERSITY RESEARCH FOUNDATION | $430,387 | Grant | Trans-NIH Recovery Act Research Support: Study of membrane proteins at the molecular level is one of the major challenges for today's biologists. ATP-binding cassette (ABC) transporters are one of the largest amd most diverse superfamily of membrane proteins found in all living organisms rangin | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $280,869 | Grant | Trans-NIH Recovery Act Research Support: Malfunction of the spindle checkpoint has been implicated in human cancers. The class of antimitotic anti-cancer drugs, such as Taxol, kills cancer cells by exploiting defects in this pathway. The proposed experiments will shed light on the molecular ba | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| THOMAS JEFFERSON UNIVERSITY | $475,508 | Grant | Trans-NIH Recovery Act Research Support: We proposed to speed the parent aims with high-precision Qpcr for hundreds of neural-genes for very large numbers of samples taken by laser capture microdissection (LCM) for single SCN neurons and for identified poplulations of light responsive neurons, k | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $289,456 | Grant | Trans-NIH Recovery Act Research Support: The long-term objective of the proposed research is to elucidate the mechanisms of drug- and xenobiotic- mediated inactivation, degradation, and turnover of cytochrome P450 enzymes. Nitric oxide synthase (NOS), the most highly regulated cytochrome P450 en | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| NORTHWESTERN UNIVERSITY | $97,938 | Grant | Trans-NIH Recovery Act Research Support: The objective of this supplement is to apply BacMAM cell culture, to improve the parent grant. It will be used to purchase equipment and the recruitment of additional work/hours of personnel support, in full accordance to the intention of the Recovery Act | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $275,333 | Grant | Trans-NIH Recovery Act Research Support: The primary aim of our parent grant focuses upon predicting the benefit of altering the properties or expression level of individual enzymes. The crux of this proposed supplementary project is to better understand the full spectrum of selective pressures | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| SALK INSTITUTE FOR BLOGICAL STUDIES | $246,590 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of this work is to understand the molecular genetic mechanisms that underlie developmental complexity. Multicellularity has evolved multiple times in the history of life and has led to an explosion of eukaryotic diversity, including nov | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF ILLINOIS | $234,903 | Grant | Trans-NIH Recovery Act Research Support: Tumor necrosis factor ? (TNF?) plays critical roles in the regulation of inflammation and immunity, but can also induce cell death. TNF? is a potent activator of NF?B, which leads to the synthesis of pro-inflammatory and anti-apoptotic factors. Therefore, | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF CALIFORNIA, SANTA BARBARA | $153,508 | Grant | Trans-NIH Recovery Act Research Support: The goal of this supplement is to accelerate discovery of the A-site nuclease by hiring a post doctoral research associate, who will determine whether any of the known E. coli exoribonucleases collaborate with RNase II to catalyze A-site cleavage. Each ex | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $294,155 | Grant | Trans-NIH Recovery Act Research Support: Molecular simulations have played important roles in biochemical and biophysical sciences. Advances have been made that have allowed extensive simulations of increasingly complex systems. Furthering these advances, the investigators proposes to develop pa | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $313,475 | Grant | Trans-NIH Recovery Act Research Support: DNA polymerase lambda (Pol;), a recently identified X-family DNA polymerase, uniquely contains an N-terminal nuclear localization signal motif, a breast cancer susceptibility protein BRCA1 C- terminal (BRCT) domain, a Proline-rich domain, and a C-terminal | Health and Human Services, Department of / National Institutes of Health | 8/12/2009 |
| UNIVERSITY OF CHICAGO, THE | $240,167 | Grant | Trans-NIH Recovery Act Research Support: Metalloprotease is the most abundant within the five protease classes in humans. Insulin degrading enzyme(IDE) is a zinc-metalloprotease that is involved in the clearance of insulin and amyloid (3 (A3), two keyproteins for the development of diabetes and | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $244,377 | Grant | Trans-NIH Recovery Act Research Support: The focus of this study is the genetics of variation in human gene expression. Our overall goals are to characterize the extent of variation in gene expression and to identify the genetic determinants of this variation. The specific aims for this renewal | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| PENNSYLVANIA STATE UNIVERSITY, THE | $384,822 | Grant | Trans-NIH Recovery Act Research Support: Understanding the events involved in the emergence of human pathogens from animal commensals/pathogens is important to our ability to confront their increasingly frequent outbreak. In an intriguing experiment of nature, the persistent commensal of a broad | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| UMDNJ-ROBERT WOOD JOHNSON MEDICAL SCHOOL | $100,531 | Grant | Trans-NIH Recovery Act Research Support: To determine if Centrin can prevent cell cycle entry following UV light treatment, and thereby provide a DNA damage checkpoint. | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $185,155 | Grant | Trans-NIH Recovery Act Research Support: R01 #1R01GM083989-01 to Dr. Audrey Gasch (PI) is aimed at understanding the role and regulation of stress- activated gene expression changes in these phenomena. Aim 1 is elucidating the mechanism of acquired stress resistance and memory of stress toler | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY | $84,500 | Grant | Trans-NIH Recovery Act Research Support: Biomedical Research: The long-term objective of our research is to understand the signaling mechanism and the physiological functions of the newly discovered Rac-cGMP signaling pathway. The main focus of the parent application is on the allosteric regul | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| PORTFOLIO MANAGEMENT CONSULTING, LLC | $112,650 | Contract | : TAS::75 0845::TAS - RECOVERY ERA PROFESSIONAL MANAGEMENT SUPPORT - OPERA INTERFACE AND GM MODULE/EVERGREENING PILOT AND ERA/NBS INTEGRATION -- These funds will be in direct support of the NIH Grants Management System activities required for NIH & ARRA fun | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $115,873 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): A major objective of high resolution imaging of cells is to visualize the molecular organization of cellular components and to determine if specific components participate in the same macromolecular complex. Efforts to | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $87,000 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement under the American Recovery and Reinvestment Act is to purchase an SGA robot to facilitate both Aims of the parent grant. The SGA robot will enhace the speed and accuracy of genetic manipulations essential to completing both | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $50,325 | Grant | Trans-NIH Recovery Act Research Support: The overreaching goal of this project is to determine the structure and mechanism of the human RISC-loading complex (RLC). The RLC catalyzes the initiation of the microRNA pathway, which is linked to many forms of human disease, and is the intracellular t | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| COLORADO STATE UNIVERSITY | $7,163 | Grant | Trans-NIH Recovery Act Research Support: The long-term objective of this work is to understand the molecular mechanisms by which hormones influence uterine smooth muscle contraction and relaxation. This proposal focuses on defining cellular and subcellular mechanisms involved in crosstalk betwee | Health and Human Services, Department of / National Institutes of Health | 7/09/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $292,762 | Grant | Trans-NIH Recovery Act Research Support: The proposed studies will increase our basic knowledge and understanding of human development. These studies will improve treatment of human infertility by providing new knowledge that will facilitate the rational development of treatments that foster im | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF PITTSBURGH THE | $82,158 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement request will serve the following specific objectives: 1) To hire a data manager/analyst. This will significantly enhance the activities of my parent R01 by increasing the capacity for data analysis. Over the last 4 years I h | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| THE JACKSON LABORATORY | $177,550 | Grant | Trans-NIH Recovery Act Research Support: The proposed studies investigate a novel cause of male germ cell maturation arrest, which occurs in many unexplained cases of human male infertility and reproductive toxicity. Identifying regulatory molecules and mechanisms will pinpoint events that, when | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| TRUSTEES OF PRINCETON UNIVERSITY, THE | $223,160 | Grant | Trans-NIH Recovery Act Research Support: The Fragile Families and Child Wellbeing Study is a longitudinal birth cohort study of approximately 3700 unmarried parents and 1200 married parents and their children. We seek funding to: 1) perform assessments at age 9 of children's health, language abi | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| NORTH DAKOTA STATE UNIVERSITY | $4,302 | Grant | Trans-NIH Recovery Act Research Support: In the developed world, the U.S. has the highest rate of adolescent pregnancy, which is associated with increased risk of fetal growth restriction and premature delivery. Both preterm delivery and low birth weight are associated with a much greater risk | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $185,768 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The overarching goal of the proposed research is to advance our understanding of how persistent and extreme exposure to political conflict and violence combines with cognitive, emotional, and self processes to influenc | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| BAYLOR COLLEGE OF MEDICINE | $35,309 | Grant | Trans-NIH Recovery Act Research Support: Squire's Quest! was a proven-effective video game that increased children's FJV consumption by 1.0 servings a day; however, total consumption was still below recommended levels, indicating that additional work was needed. Additionally, results revealed th | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $35,115 | Grant | Trans-NIH Recovery Act Research Support: This ARRA funding makes possible the extension of our ApoE studies into an infection model, relevant to a major threat to the cognitive development and growth of the young child by repeated enteric infections. We will examine the relevance of malnutrition | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF TEXAS AT AUSTIN | $107,212 | Grant | Trans-NIH Recovery Act Research Support: This project investigates the degree to which higher rates of health problems among race/ethnic minority children of all economic strata and among poor children from all race/ethnic populations prior to the start of elementary school put them at an academ | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| EMORY UNIVERSITY | $245,138 | Grant | Trans-NIH Recovery Act Research Support: Spinal Muscular Atrophy (SMA) is a common inherited neurodegenerative disease caused by mutations or deletions in the SMN1 gene that encodes for the ubiquitous Survival of Motor Neuron Protein (SMN), which is essential for the assembly of spliceosomal snR | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| CHILDRENS HOSPITAL OF PHILADELPHIA | $248,939 | Grant | Trans-NIH Recovery Act Research Support: With over 57,000 infants born every year in the United States with a birth weight under 1500 grams, their care is a rapidly growing public health concern. Ensuring that this high-risk group of patients receives appropriate care after discharge has become | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $33,990 | Grant | Trans-NIH Recovery Act Research Support: The nutritional status of the mother is a key factor for the development and growth of the fetus. Vitamin A is an essential nutrient for the developing embryo, which depends on maternal circulating vitamin A (or retinoids) to fulfill its needs. Indeed, em | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $9,059 | Grant | Trans-NIH Recovery Act Research Support: This grant provided a summer research experience for 1 college students in health-related scientific research. This award supplements 5R01HD058573-02, Using Virtual Reality to Train Children in Pedestrian Safety, a Randomized Controlled Trial research pr | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY | $336,000 | Grant | Trans-NIH Recovery Act Research Support: Through alternative splicing, most human genes produce multiple distinct mRNA and protein isoforms, that may differ in structure, localization and function. To understand how splicing is controlled, we are seeking to identify sequences that can act as sp | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK INC | $300,933 | Grant | Trans-NIH Recovery Act Research Support: PROJECT SUMMARY: The goal of this project is to develop a computational framework for accurately predicting the in vivo occupancy profile of transcription factors (TFs) along the genome from the underlying DNA sequence. Techniques from equilibrium statist | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| DUKE UNIVERSITY | $171,547 | Grant | Trans-NIH Recovery Act Research Support: In response to NOT-OD-09-056, we request an administrative supplement to R01 HG004065, ?Modeling the structure & evolution of regulatory regions in eukaryotic genomes?. Transcriptional control is undoubtedly one of the important aspects of gene expression | Health and Human Services, Department of / National Institutes of Health | 9/10/2009 |
| DANA-FARBER CANCER INSTITUTE, INC. | $350,000 | Grant | Trans-NIH Recovery Act Research Support: Whole genome tiled arrays from Affymetrix, Agilent, and Nimblgen allow biologists to conduct unbiased chromatin immunoprecipitation coupled with DNA microarray analysis (ChlP-chip) to study the genome level in vivo binding of transcription factors (TFs). | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE | $597,319 | Grant | Trans-NIH Recovery Act Research Support: Gene expression in response to environmental stimuli is dictated by chemical modifications of DNA and chromosomal DNA-packing histones, which work in concert to signify distinct nuclear activities such as chromatin structure change, gene activation and si | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| CASE WESTERN RESERVE UNIVERSITY | $191,352 | Grant | Trans-NIH Recovery Act Research Support: The techniques of chromatin immunoprecipitation coupled with DNA microarray (ChIP-chip) and sequencing (ChIP-seq) have gained widespread popularity among the greater scientific community. The data generated from such analyses have begun to provide valuabl | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| UNIVERSITY OF WASHINGTON | $276,129 | Grant | Trans-NIH Recovery Act Research Support: Due to recent progress indicating the feasibility of using MspA for nanopore sequencing we propose to intensify our research by adding two researchers. The scientific goals laid out in the parent program for the reviewed R01 grant remain the same. | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $20,733 | Grant | Trans-NIH Recovery Act Research Support: Signaling in endothelial growth and angiogenesis (Administrative Summer Supplement) This project is to understand signaling in endothelial growth and angiogenesis. Specifically, this award is about to examine the role of BMPER (bone morphogenetic protein | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| DUKE UNIVERSITY | $6,418 | Grant | Trans-NIH Recovery Act Research Support: P-ARRESTINS AND GRKs IN CARDIOVASCULAR FUNCTION. G protein coupled receptors (GPCRs) such as those for catecholamines and angiotensin II regulate cardiovascular functions including vasoconstriction and vasodilation; vascular smooth muscle cell (VSM) mitog | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $17,154 | Grant | Trans-NIH Recovery Act Research Support: Role of Adenosine in Allergic Lung Disease - ARRA The supplement's purpose is to expose undergrad student(s) to the excitement of biomedical research experience involving both in vito and in vivo methods. The student will assist with the induction of al | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $166,830 | Grant | Trans-NIH Recovery Act Research Support: Epidemiologic studies have clearly demonstrated that patients with a preponderance of abdominal or visceral adiposity are at profoundly higher risk for cardiovascular disease than those with preferential accumulation of body fat in the gluteofemoral regio | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| UNIVERSITY OF CONNECTICUT | $288,436 | Grant | Trans-NIH Recovery Act Research Support: The goal of this research supplemental grant will be to provide a clear conclusion about the contributing domain of TRPM7 in cardiac fibrogenesis, and therefore define which domain of TRPM7 should serve as a therapeutic target for fibrosis related heart d | Health and Human Services, Department of / National Institutes of Health | 7/10/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $282,277 | Grant | Trans-NIH Recovery Act Research Support: Aldosterone is implicated in the process of myocardial remodeling and failure. Aldosterone may affect myocardial phenotype by regulating inflammation, myocyte contraction and relaxation, oxidative stress, and the interstitial matrix through a variety of | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF MONTANA SYSTEM | $210,067 | Grant | Trans-NIH Recovery Act Research Support: This project is an administrative supplement to appoint a research specialist and procure supplies to facilitate out research aimed at determining the mechanism of by which prostaglandin (PG)I2 modulates allergic inflammation in asthma. Allergic asthma i | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $215,216 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the award funding is to retain the job of the highly qualified research specialist, Mr. Kent Smith, working on key experimentation of our R01 grant. The focus of our project is in the area of lipids, inflammation and accelerated cardiovascu | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| THE VANDERBILT UNIVERSITY | $210,056 | Grant | Trans-NIH Recovery Act Research Support: The broad objectives of the work are to clarify the mechanisms by which thrombin localized on fibrin (Fbn) clots can either be inactivated by its target serine protease inhibitors (serpins) heparin cofactor II (HCII) and antithrombin (AT), or protected by | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| SEATTLE CHILDREN'S HOSPITAL | $274,435 | Grant | Trans-NIH Recovery Act Research Support: Mechanistic studies of pulmonary toxicity of styrene -- Wide range effects of occupational styrene exposure have been reported to cause severe acute toxic effects. Inhaled styrene has been found to produce respiratory toxicity in human and animals. The ov | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| UNIVERSITY OF HAWAII SYSTEMS | $66,005 | Grant | Trans-NIH Recovery Act Research Support: Hypoxia inducible factor-1 is a principal oxygen sensing molecule in all vertebrates. It is a transcription factor that is regulated by the effect of ambient oxygen concentration on its stability. HIF1 regulates a panoply of genes involved in response to | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| DUKE UNIVERSITY | $19,250 | Grant | Trans-NIH Recovery Act Research Support: I am requesting an administrative supplement to hire an Undergraduate Student for an NIH-funded application (HL081395) under the auspices of the American Recovery and Reinvestment Act of 2009 (NOT-OD-060). The goals of this administrative supplement are t | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $60,956 | Grant | Trans-NIH Recovery Act Research Support: One underserved group is the 4 million homeless persons in the US among whom cigarette smoking rate is an alarming 70% or more; these rates are 3 times higher than national average. Two of the three leading causes of death among homeless persons, heart di | Health and Human Services, Department of / National Institutes of Health | 7/27/2009 |
| BAYLOR COLLEGE OF MEDICINE | $238,220 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this study is to understand how protein phosphatases regulate functions of blood cells called platelets with the long term goal of discovering new therapeutic targets for anti-thrombotic therapy. In particular, this supplement will examine | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| PALO ALTO INSTITUTE FOR RESEARCH AND EDUCATION, INC. | $240,149 | Grant | Trans-NIH Recovery Act Research Support: This American Recovery and Reinvestment Act Administrative Supplement is designed to increase the tempo of research activity in order to completely achieve the scientific goals set forth in the associated R01 grant (R01 HL082662, An Autoimmune Basis for P | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF KENTUCKY | $273,755 | Grant | Trans-NIH Recovery Act Research Support: The mechanisms underlying the initiation and development of atherosclerosis are not fully understood. As outlined in the response to retention hypothesis, the retention of atherogenic lipoproteins within the sub-endothelial space by their interactions wit | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| THE VANDERBILT UNIVERSITY | $284,509 | Grant | Trans-NIH Recovery Act Research Support: Acute myocardial infarction and chronic cardiomyopathies damage healthy heart tissue disrupting the normal electronmechanical continuum of ventricular muscle. Over the last years, a number of studies in animal models have suggested that transplantation o | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| TEXAS A&M UNIVERSITY SYSTEM,THE | $202,670 | Grant | Trans-NIH Recovery Act Research Support: This proposal is based on the overall hypothesis that non-collagenous extracellular matrix (ECM) proteins play vital roles in the formation of dentin by odontoblasts and in the homeostatic mechanisms of formation and breakdown of bone by osteoblasts, oste | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF KENTUCKY | $276,211 | Grant | Trans-NIH Recovery Act Research Support: The evolving understanding of mechanisms contributing to the development of atherosclerosis and neointima formation following vascular injury has identified members of the nuclear hormone receptor superfamily as key transcriptional regulators of gene expr | Health and Human Services, Department of / National Institutes of Health | 8/15/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $98,658 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Congestive heart failure (CHF) outcomes depend critically on patients' effective self-management of their condition. Yet, patients with CHF are often frail, indigent, and socially isolated, factors that limit their abi | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $326,822 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of this project is to determine the role of viral pathogens in the development of vascular diseases such as atherosclerosis, restenosis, and transplant vascular sclerosis (TVS). All of these diseases are the result of either mechanical | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $184,843 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the American Recovery and Reinvestment Act (ARRA) funded Administrative Supplement is to hire one new research staff member to advance research supported by the parent grant 5R01HL085561-04 (Heart Failure, Chronic Kidney Disease, and Renin | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF MARYLAND | $264,798 | Grant | Trans-NIH Recovery Act Research Support: Proposed is an ancillary study to the Transfusion Therapy Trial for Functional Outcomes in Cardiovascular Patients Undergoing Surgical Hip Fracture Repair (FOCUS) to examine the impact of the hemoglobin interventions on delirium in a sub-sample of 200 sub | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| UNIVERSITY OF NEBRASKA | $220,774 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the proposed research project is to elucidate the molecular basis of physiological adaptation to high-altitude hypoxia, a condition resulting from a reduced supply of oxygen to the cells of respiring tissues. Specifically, the proposed rese | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| UNIVERISTY OF MISSISSIPPI MEDICAL CENTER | $223,569 | Grant | Trans-NIH Recovery Act Research Support: This supplement is designed to provide salary and research funds for hiring of a post-doctoral fellow to support the recently funded, new investigator grant 5R01HL088421-02 entitled The Renal Medulla and Hypertension. The post doctoral fellow (Dr. Eva Cs | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| NORTHERN CALIFORNIA INSTITUTE FOR RESEARCH AND EDUCATION, INC. | $308,535 | Grant | Trans-NIH Recovery Act Research Support: Alveolar epthelial wound healing is required for recovery from acute lung injury and ARDS, but the mechanisms for epithelial repair in the lung are not fully understood. Previous work has shown that one pathway that promotes epithelial migration and repai | Health and Human Services, Department of / National Institutes of Health | 8/12/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $269,045 | Grant | Trans-NIH Recovery Act Research Support: This supplement provides funding for 1 FTE postdoctoral fellow and lab funds for 2 years to expand the scope of a funded RO1. Since funding began this summer, Dr. Polina Sysa has joined the project and is now concentrating on increasing the mice colony an | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON | $251,781 | Grant | Trans-NIH Recovery Act Research Support: HIV infection of primary human cells typically requires interaction of Env gp120 with both the primary receptor CD4 and a chemokine receptor, either CCR5 or CXCR4, followed by Env gp41-induced fusion. Involvement of other factors and processes are likely, | Health and Human Services, Department of / National Institutes of Health | 7/30/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $7,649 | Grant | Trans-NIH Recovery Act Research Support: Determinants of AAV Lung Tropism ARRA PURPOSE OF THE SUPPLEMENT Aim 1 of the parent PPG project hinges on highthroughput molecular cloning. The current supplement request is focused on accelerating research goals outlined specifically in these aims. Cu | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| THE VANDERBILT UNIVERSITY | $242,458 | Grant | Trans-NIH Recovery Act Research Support: In the parent grant, we hypothesized that TLR4 deficiency would result in decreased macrophage accumulation and inflammation in WAT. We have completed those studies and confirmed out hypothesis to be correct. In addition, based upon current literature d | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $18,090 | Grant | Trans-NIH Recovery Act Research Support: We have shown that PGIS promoter variants lead to functional differences in mRNA expression. Because of the rich variety of promoter sequence variants and their close association with a variable number of tandem repeats, direct DNA sequencing has been th | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| GEORGIA HEALTH SCIENCES UNIVERSITY RESEARCH INSTITUTE, INC. | $256,075 | Grant | Trans-NIH Recovery Act Research Support: Cardiovascular disease is the leading cause of death for both men and women in the United States and the world. There is a profound pattern in the time of day at which the death occurs. It is in the morning, when the endothelium is most vulnerable and blo | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| CHILDREN'S HOSPITAL CORPORATION, THE | $308,171 | Grant | Trans-NIH Recovery Act Research Support: Sickle cell disease (SCD) is a debilitating genetic disorder that affects mainly African-Americans. It is characterized by red blood cell hemolysis, chronic anemia, and recurrent episodic pain. Elevated levels of endothelin-1 (ET-1), low red cell Mg2+ lev | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| UNIVERSITY OF IOWA, THE | $232,622 | Grant | Trans-NIH Recovery Act Research Support: Cardiac arrhythmias are the leading cause of death among heart failure (HF) patients. A growing body of evidence indicates that dysregulation in intracellular Ca2+ is a critical factor in these arrhythmias. Importantly, alterations in myocyte Ca2+ release | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $91,602 | Grant | Trans-NIH Recovery Act Research Support: Endothelial lineage specification and differentiation in vertebrate embryos - AR In the proposed research, we intend to analyze the emergence of hemogenic endothelium during development using zebrafish as model system. The ARRA fund will allow us to retai | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF CINCINNATI | $35,268 | Grant | Trans-NIH Recovery Act Research Support: Though the role of genes in heart disease is appreciated, there is currently little understanding of the mechanism by which the transcription factor NF-kB contributes to the antithetical processes of cardioprotection and ischemia/reperfusion (I/R) injury. | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $361,241 | Grant | Trans-NIH Recovery Act Research Support: Patient Outcomes 6 and 12 Months After ALTA, OMEGA and EDEN ARDS Network Trials: (1) Acelerating the pace and achievement of the parent grant via maximizing recruitment and retention of study participants, and (2) adding value to the parent grant via new | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| NORTHWESTERN UNIVERSITY | $264,196 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this administrative supplement is to expand on the surgical animal model for studying the effects of coronary artery narrowing that mimicks natural disease progression. In the parent grant, an acute stenosis model with short periods (5-10 | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| NORTHWESTERN UNIVERSITY | $252,857 | Grant | Trans-NIH Recovery Act Research Support: The administrative supplement request is for the hiring of a two year fulltime-equivalent position for a post-doctoral fellow. This will also be used for supplies the fellow will be using to investigate glucocorticoid receptor translational isoforms in re | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| UNIVERSITY OF WASHINGTON | $314,104 | Grant | Trans-NIH Recovery Act Research Support: This a revision application of 5R33CA099139-04 Parallel Peptide Tandem Mass Spectrometry to the program NOT-OD-09-058 NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. The original R33 award was devised around a m | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF NEW MEXICO | $343,460 | Grant | Trans-NIH Recovery Act Research Support: This is an administrative supplement proposal to dramatically speed the optimization of the low cost portable flow cytometer that we have been developing to fulfill the goals our parent grant. This flow cytometer uses acoustic focusing to position cells w | Health and Human Services, Department of / National Institutes of Health | 8/24/2009 |
| ROSE LI & ASSOCIATES INC | $25,000 | Contract | : Provide comprehensive support for the Division of Behavioral and Social Research (DBSR) at the National Institute on Aging, National Institutes of Health, for science management, evaluation activities, writing/editing and document production, and informat | Health and Human Services, Department of / National Institutes of Health | 8/06/2009 |
| SCIENCE APPLICATIONS INTERNATIONAL CORPORATION | $437,640 | Contract | : Provide software development and support services to the NIH Office of Extramural Research (OER) for the Electronic Research Administration (eRA) systems and databases as part of an overall modernization effort. SAIC developers work on cross-functional t | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| D'VINCI INTERACTIVE INC | $57,458 | Contract | : Translation, creation of Protection of Human Research Participants eLearning website in Spanish, database, hosting, maintenance and support. | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $272,133 | Grant | Trans-NIH Recovery Act Research Support: We propose to develop and maintain a Data Coordinating Center (DCC) that will support a consortium of transplant centers (Clinical Centers) by conducting epidemiological research on the medical and functional outcomes of living individuals who have donate | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $152,652 | Grant | Trans-NIH Recovery Act Research Support: The Bronx Center to Reduce and Eliminate Ethnic and Racial Health Disparities (BxCREED) of the Albert Einstein College of Medicine (AECOM) is a P-60 Center of Excellence in Partnerships for Community Outreach, Research on Health Disparities and Training ( | Health and Human Services, Department of / National Institutes of Health | 5/28/2009 |
| UNIVERSITY OF MASSACHUSETTS | $7,091,800 | Grant | National Center for Research Resources, Recovery Act Construction Support: Funds are to renovate approximately 23,400 (gross) square feet of research space in the Lederle Graduate Research Center (LGRC), Towers A and C, at the University of Massachusetts Amherst. The space to be renovated is presentltly shared between the Departme... Show more | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| UNIVERSITY OF MASSACHUSETTS | $52,366 | Grant | Trans-NIH Recovery Act Research Support: An administrative supplement is requested to support 3 undergraduate students to engage in full time research over the summer months of 2009 and 2010. The research proposed in this supplement request is part of a funded R01 project (NIH 5R01A1064588-03, E | Health and Human Services, Department of / National Institutes of Health | 6/03/2009 |
| UNIVERSITY OF MASSACHUSETTS | $57,420 | Grant | Trans-NIH Recovery Act Research Support: The Chemistry-Biology Predoctoral Training Grant supports graduate students in Chemistry, Molecular and Cellular Biology, Chemical Engineering, and Polymer Science and Engineering who are training for research career opportunities in areas that cross the | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $170,662 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Physicians have many questions when seeing patients. Primary care physicians are reported to generate between 0.7 and 18.5 questions for every 10 patient visits. The published medical literature is an important resourc | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $172,210 | Grant | Trans-NIH Recovery Act Research Support: The long-term objective of the parent proposal is to advance patient safety and reduce health care costs by developing automated methods that discover novel adverse drug events (ADE) based on information in clinical documents. The purpose of this competit | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $141,172 | Grant | Trans-NIH Recovery Act Research Support: It has become increasingly clear that males and females differ even more dramatically than we previously thought. Not only do they exhibit differing responses to stress and environmental experience, but they can also respond in opposite directions. In rat | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $39,795 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): In 1999, the United States Center for Disease Control (CDC) named family planning as one of the top ten Great Public Health Achievements of the twentieth century. However, the lack of data and credible estimation strat | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| CLEVELAND STATE UNIVERSITY | $213,000 | Grant | Trans-NIH Recovery Act Research Support: Programmed cell death (apoptosis) is induced concomitant with differentiation in skeletal myoblasts and other systems. In skeletal myoblasts, these two processes result in mutually exclusive physiologically important endpoints. However, the coordinate t | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| FLORIDA INTERNATIONAL UNIVERSITY | $36,795 | Grant | Trans-NIH Recovery Act Research Support: This is a summer supplement award to the existing parent R-15 grant (R15CA119253) that was awarded for a 2-year period. The objective of this administrative supplement award is to provide summer research experience for (undergraduate/high school) student | Health and Human Services, Department of / National Institutes of Health | 6/03/2009 |
| MISSISSIPPI STATE UNIVERSITY | $71,500 | Grant | Trans-NIH Recovery Act Research Support: The rate-limiting step in reverse cholesterol transport from macrophages is the hydrolysis of cholesteryl esters to free cholesterol, which is subsequently transported out of the cell to cholesterol acceptors. In human macrophages, the enzyme responsible | Health and Human Services, Department of / National Institutes of Health | 9/02/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $78,202 | Grant | Trans-NIH Recovery Act Research Support: A custom spectrofluorimeter was designed and ordered from Horiba Jobin Yvon. A gifted undergraduate student was hired to work in the laboratory whom has been deleteriously impacted by the economic downturn. | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| RFCUNY -QUEENS COLLEGE | $97,094 | Grant | Trans-NIH Recovery Act Research Support: Academic Research Enhancement Awards (AREA): To support small scale research projects conducted by faculty in primarily baccalaureate degree-granting domestic institutions. Overall growth and body size are regulated by genetic as well as environmental f | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| MIAMI UNIVERSITY | $30,000 | Grant | Trans-NIH Recovery Act Research Support: The primary purpose of our research program is to investigate a new class of room temperature ionic liquids, alkylammonium formates (AAFs), as mobile phase alternatives to organic solvents for liquid chromatography (LC) of proteins. Organic solvents such | Health and Human Services, Department of / National Institutes of Health | 10/01/2009 |
| WESLEYAN UNIVERSITY | $76,037 | Grant | Trans-NIH Recovery Act Research Support: Telomeres are DNA-protein structures at the ends of eukaryotic chromosomes that are protected and maintained by specialized proteins including the reverse transcriptase telomerase. Telomere defects have been linked with both aging and transformation. A cr | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| MISSOURI SYSTEM, UNIVERSITY OF | $44,930 | Grant | Trans-NIH Recovery Act Research Support: The first Aim of the parent award is: 1) to generate many mutants in the yeast genome relatively evenly distributed through the complex promoter of one yeast gene, 2) to assay expression of this gene in all these promoters mutants under all eight combinat | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| EMORY UNIVERSITY | $4,827,520 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this award of American Recovery and Reinvestment Act (ARRA) funds is to accelerate the tempo of scientific research at the Emory HIV/AIDS Clinical Trials Unit (EHCTU). The ARRA funds are requested specifically to accelerate the research bei | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| THE GEORGE WASHINGTON UNIVERSITY | $3,264,706 | Grant | Trans-NIH Recovery Act Research Support: Washington DC has among the highest HIV/AIDS rates in the United States, with at least 3% of the adult population living with HIV/AIDS; 7.1% of black males and 2.8% of black females have been diagnosed and are living with HIV/AIDS. In response to the crit | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| CANCER PREVENTION INSTITUTE OF CALIFORNIA | $501,798 | Grant | Trans-NIH Recovery Act Research Support: This request for a two-year Administrative Supplement was submitted in response to Notice NOT-OD-09-056, ?Notice of Availability of Recovery Act Funds for Administrative Supplements?, for grant U01 CA69417, ?Northern California Collaborative Family Regist | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $205,373 | Grant | Trans-NIH Recovery Act Research Support: Molecular Regulation in Reproduction ARRA In our recent work on the original aims of U54 HD 035041 ?Molecular Regulation in Reproduction? interesting new observations focused attention on the role of the androgen receptor and its coregulators in the aberr | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| CHILDREN'S RESEARCH INSTITUTE | $10,664 | Grant | Trans-NIH Recovery Act Research Support: Funding for Summer Student worker, James Bowe III, who worked with Dr. Terence Partridge, PhD. The focus of the summer experiences is on molecular biochemistry and molecular genetics, as applied to molecular pathophysiology and genomics (genetic modifier | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| GEORGETOWN UNIVERSITY (THE) | $242,939 | Grant | Trans-NIH Recovery Act Research Support: Status of Year 1 Benchmarks as of 3.29.11: The PROTECT DC project is making good progress towards the above mentioned specific aims. ? Adding an additional recruitment site with in Washington DC ? 100% Complete o The Georgetown University IRB and the Pro | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| CHARLES DREW UNIVERSITY OF MEDICINE AND SCIENCE | $25,000 | Grant | Trans-NIH Recovery Act Research Support: Charles R. Drew University of Medicine and Science (DREW) a minority institution (MSI/HBCU) located in South Central Los Angeles, is planning a partnership with the world renowned Jonsson Comprehensive Cancer Center (JCCC) at University of California Los | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| THE VANDERBILT UNIVERSITY | $294,478 | Grant | Trans-NIH Recovery Act Research Support: The Collaborative to Build Community Capacity for Research is a joint project of Vanderbilt University Medical Center, Meharry Medical College, and Tennessee State University which proposes to create sustainable mechanisms and processes to develop and enh | Health and Human Services, Department of / National Institutes of Health | 9/26/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $317,307 | Grant | Trans-NIH Recovery Act Research Support: The University of Michigan Clinical and Translational Sciences Award (UM CTSA) will focus the formidable strengths of one of the world's finest research institutions on supporting and facilitating clinical and translational 'team science'. The UM CTSA wil | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| CASE WESTERN RESERVE UNIVERSITY | $978,776 | Grant | Trans-NIH Recovery Act Research Support: The supplement to the Center for Translational Science Award (UL1-RR024989) based at Case Western Reserve University, and involving University Hospitals, Cleveland Clinic, and Metro Health Center, will Advance Translational (T1& T2) Research through the d | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $400,000 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this application is to enhance both the process and benefits of clinical andtranslational research by bringing together the diverse resources of the Johns Hopkins Medical Institutions (JHMI) and creating a new model for carrying out scienti | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| NEW JERSEY INSTITUTE OF TECHNOLOGY | $92,418 | Grant | Trans-NIH Recovery Act Research Support: Award Title: Partitioning to Support Auditing and Extending the UMLS/Admin Supplement. The proposed research supports our original application concerning auditing and extending of the UMLS. We design techniques for finding inconsistencies in the widely | Health and Human Services, Department of / National Institutes of Health | 8/19/2009 |
| UNIVERSITY OF PITTSBURGH THE | $224,578 | Grant | Trans-NIH Recovery Act Research Support: The parental proposal aims to study the in vivo binding specificity of certain types of transcription factors (TFs). The TFs we are interested in are those that by themselves they have relatively weak binding, and depend on co-factors to achieve the neede | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| LOUISIANA STATE UNIVERSITY SYSTEM | $82,143 | Grant | Trans-NIH Recovery Act Research Support: This proposal for Recovery Act Administrative Supplement Funds has two important goals: 1) A Recovery Act Supplement will be used to purchase equipment that will accelerate our progress on the Specific Aims of the parent grant. We will upgrade an existin | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| DUKE UNIVERSITY | $39,000 | Grant | Trans-NIH Recovery Act Research Support: Devastating cardiac developmental malformations are linked to environmental toxins, but the biological mechanisms are not known. Our objective is to create heart specific transgenic zebrafish fluorescent reporter strains that will signal when vertebrate | Health and Human Services, Department of / National Institutes of Health | 9/02/2009 |
| UNIVERSITY OF MASSACHUSETTS | $359,053 | Grant | Trans-NIH Recovery Act Research Support: This Administrative Supplement to the Currently Funded Project Epigenetic Changes in Frontal Lobe of Schizophrenics, 5R01MH071476-04, will, as part of the American Recovery and Reinvestment Act of 2009, expand our research goals via the incorporation of n | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| THE VANDERBILT UNIVERSITY | $174,071 | Grant | Trans-NIH Recovery Act Research Support: Increasing data indicate that emotional stimuli gain preferential access to attentional resources. This effect can be instantiated as improved detection time, enhanced cortical responses, and greater disruption in processing concurrent or immediately subs | Health and Human Services, Department of / National Institutes of Health | 9/27/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO | $300,000 | Grant | Trans-NIH Recovery Act Research Support: While cross-sectional studies show that drug abuse, impulsivity, serotonin dysregulation, and stressful life events are associated with suicide, data regarding the specific relationships among these factors are limited. A recent NIDA-sponsored workgroup i | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| UNIVERSITY OF CINCINNATI | $730,065 | Grant | Trans-NIH Recovery Act Research Support: Both bipolar mania and depression are characterized by mood instability and marked behavioral changes that appear to involve dysfunction of the anterior limbic network (ALN), a group of brain regions involved in emotional regulation and modulation. Functi | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $175,000 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Previous research has suggested that earlier intervention may contribute to better outcomes in autism. Answering the question how early? has significant health and educational implications for age of screening for auti | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $478,021 | Grant | Trans-NIH Recovery Act Research Support: We propose additional quantitative, state-of-the-art image measurements of the developing brain and to speed-up the cross-sectional component of data collection. Both targets will contribute to economy by recruiting additional support staff. We propose | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF ILLINOIS | $10,584 | Grant | Trans-NIH Recovery Act Research Support: For the last 20 years, we have invited promising graduate and undergraduate students to participate in our research program during summers at the Marine Biological Laboratory, hosting 1-2 each year. At least 14 undergraduates have come through the laborat | Health and Human Services, Department of / National Institutes of Health | 7/27/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $173,250 | Grant | Trans-NIH Recovery Act Research Support: This award is an administrative supplement to RO1 NS025044. It provides funds to support the salary (and associated benefits, plus some supply costs) for a UC Davis postdoctoral fellow in my laboratory for 2 years, to accelerate the studies we are carryi | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| CORNELL UNIVERSITY, INC | $250,359 | Grant | Trans-NIH Recovery Act Research Support: Much of the ability to move depends upon networks of neurons in the spinal cord and hindbrain. Recent evidence indicates that there is a relatively simple structural and functional organization in spinal cord that may extend into the hindbrain. This propo | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $12,485 | Grant | Trans-NIH Recovery Act Research Support: Metabotropic Glu Receptors in Traumatic Brain Injury (NIH NS29995) (Administrative Supplement Notice for Students and Science Educators under the Recovery Act). The award is for creating summer employment for students and expediting the accomplishment of | Health and Human Services, Department of / National Institutes of Health | 7/24/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $13,368 | Grant | Trans-NIH Recovery Act Research Support: The goals set forth for this project were designed from our continuing desire to improve the quality of biomedical literature as well as provide employment and enhancement opportunities for the very scientists who depend on such information. | Health and Human Services, Department of / National Institutes of Health | 8/19/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $179,859 | Grant | Trans-NIH Recovery Act Research Support: The parent grant to this project longitudinally measures sleep and EEG changes across childhood and adolescence. One specific aim of the parent project is to establish maturational curves that will provide the baseline data needed for future studies of s | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| BAYLOR COLLEGE OF MEDICINE INC | $13,508 | Grant | Trans-NIH Recovery Act Research Support: This grant provided a summer research experience for Mr, SiyuanShen, an undergraduate student at the University of Washington in Seattle, in health-related scientific research.The student applied dimensional reduction techniques to simplify a highly compl | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $80,000 | Grant | Trans-NIH Recovery Act Research Support: Since AscI1 is critical in transitioning cells from a progenitor state to a differentiated state, studies of the regulation of AscI1 hold significance for their fundamental contributions to multiple areas of concern to public health such as 1) manipulatio | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $183,693 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplement is to enhance our ability to test models for the mechanisms by which neurons die during normal development and in pathological conditions such as neurodegenerative disorders. In particular, the funds awarded were to retain | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $100,799 | Grant | Trans-NIH Recovery Act Research Support: Songbirds provide an animal model for human speech perception and production, and for developmentally restricted forms of learning and memory, in which it is possible to causally link specific behaviors and their underlying neural circuitry. Birds, like h | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| CASE WESTERN RESERVE UNIVERSITY | $98,910 | Grant | Trans-NIH Recovery Act Research Support: Prolonged mild hypoxia initiates a sequence of vascular and metabolic adaptations in the rat brain. Angiogenesis and the resultant increased capillary density that occurs over a 3 week time course is an important aspect of the adaptation process. The long | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| THE WASHINGTON UNIVERSITY | $55,878 | Grant | Trans-NIH Recovery Act Research Support: Impaired axonal transport may play an early, pivotal role in a variety of neurodegenerative disorders including Parkinson's disease (PD). When axon transport is disrupted, trophic support is lost, synaptic vesicles and transmitters are depleted, biologica | Health and Human Services, Department of / National Institutes of Health | 7/31/2009 |
| UNIVERSITY OF TEXAS AT DALLAS | $36,022 | Grant | Trans-NIH Recovery Act Research Support: A common feature of most neurological diseases is the premature and aberrant degeneration of neurons. A variety of molecules involved in the promotion or inhibition of neuronal survival have been identified. This proposal focuses on histone deacetylases ( | Health and Human Services, Department of / National Institutes of Health | 7/21/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $177,916 | Grant | Trans-NIH Recovery Act Research Support: Parkinson's disease (PD) is an age-related neurodegenerative disorder characterized by resting tremor, rigidity and bradykinesia. These clinical features are thought to arise from reduced dopaminergic input to the striatum, which is caused by the degenera | Health and Human Services, Department of / National Institutes of Health | 8/20/2009 |
| UNIVERSITY OF UTAH, THE | $265,937 | Grant | Trans-NIH Recovery Act Research Support: Duchenne Muscular Dystrophy (DMD) and Becker Muscular Dystrophy (BMD) are devastating disorders. Both are associated with mutations in the dystrophin gene, a huge gene with 79 exons spread over 2.4 million bases of genomic sequence. Deletions of large por | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| THE VANDERBILT UNIVERSITY | $65,000 | Grant | Trans-NIH Recovery Act Research Support: The goal of this proposal is to investigate how the brain encodes tactile motion information in the brain. Responses within different areas of primary somatosensory cortex (SI) will be examined (areas 3a, 3b, 1, and 2). Central to understanding their func | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $28,583 | Grant | Trans-NIH Recovery Act Research Support: This project seeks to understand how the energy carried by every touch activates force-sensitive ion channels in sensory neurons. These protein complexes, known as mechano-electrical transduction or MeT channels, are critical not only for touch sensation, | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF MARYLAND | $128,270 | Grant | Trans-NIH Recovery Act Research Support: The hippocampus is a brain region regulating two (2) divergent but related life functions; learning and memory and regulation of the hypothalamatic-pituitary-adrnenal stress axis. The rodent provides a powerful model for investigating the importance of th | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $164,392 | Grant | Trans-NIH Recovery Act Research Support: The brain microvasculature is comprised of a specialized class of endothelium that forms a cellular barrier between the bloodstream and the interstices of the brain. This so-called blood-brain barrier (BBB) distinguishes the brain microvasculature from p | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| TRUSTEES OF TUFTS COLLEGE INC | $44,194 | Grant | Trans-NIH Recovery Act Research Support: This award is intended to provide (1) a summer research experience for undergraduate students with an interest in pursuing a career in neuroscience, (2) an accelerated tempo of work on existing projects by employing students to carry out less specialized | Health and Human Services, Department of / National Institutes of Health | 7/19/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $58,393 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Delivery of neurotrophic factors to sites of spinal cord injury (SCI) has been shown to induce axonal growth from different neuronal populations. While cellular growth factor gene delivery is a potent means of promotin | Health and Human Services, Department of / National Institutes of Health | 8/19/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $181,906 | Grant | Trans-NIH Recovery Act Research Support: We have demonstrated that postsynaptic activity in muscles regulate the development of Schwann cells and the onset of myelination. Further investigation may reveal novel mechanisms of myelination and provide important insights for a better understanding | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| UNIVERSITY OF CONNECTICUT | $229,587 | Grant | Trans-NIH Recovery Act Research Support: Clinically, ischemic stroke is recognized as a sexually dimorphic disease. Reproductive hormones are a major contributor to differences in male and female pathobiology. However, emerging data clearly show that outcome from stroke is shaped by biologic sex | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $128,130 | Grant | Trans-NIH Recovery Act Research Support: Develop a blood test for ischemic stroke by developing a training set of blood samples and determining whether the genes from these samples predict stroke and cause of stroke in the second set of samples. | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $258,302 | Grant | Trans-NIH Recovery Act Research Support: This project aims at determining the histamine receptor subtypes as well as of the A-type voltage-gated potassium channels present in preoptic and interior hypothalamic neurons involved int thermoregulation. | Health and Human Services, Department of / National Institutes of Health | 8/19/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $176,222 | Grant | Trans-NIH Recovery Act Research Support: The broad objective of this project is to analyze at the molecular level the regulatory mechanisms of altered RNA splicing that are controlled by the formation of pathological MBNL1 mega-complexes in myotonic dystrophy 1 (DM1) patient cells. The genetic d | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | $31,949 | Grant | Trans-NIH Recovery Act Research Support: Negative masking is the suppression of nocturnal locomotor activity that occurs when a mammal is exposed to light. On the one hand, it has been considered to be either an inconvenience for circadian rhythm assessment insofar as it can obscure underlying e | Health and Human Services, Department of / National Institutes of Health | 8/19/2009 |
| UNIVERSITY OF PITTSBURGH THE | $112,752 | Grant | Trans-NIH Recovery Act Research Support: This is a supplementary fund to stimulate progress of the ongoing RO1 project. It includes personnel funds to accelerate research progress of both basic research and applied objectives. Chronic recording improvement is the immediate application-driven g | Health and Human Services, Department of / National Institutes of Health | 8/19/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $19,096 | Grant | Trans-NIH Recovery Act Research Support: Inflammation is a major component in the pathogenesis of brain injury during stroke. Cell signaling pathways prominently involved in the inflammatory cascade are initiated through Toll-like receptors (TLRs). Thus TLRs may be novel targets for stroke thera | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| DUKE UNIVERSITY | $14,040 | Grant | Trans-NIH Recovery Act Research Support: We propose to study the political economy of tobacco in low- and middle-income countries in Southeast Asia. Through a regional research and capacity building program, we seek to enable those in the region to respond more effectively to the challenge of to | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| EMORY UNIVERSITY | $105,284 | Grant | Trans-NIH Recovery Act Research Support: A Novel Approach for Diagnosis and Newborn Screening for 22Q11 Deletion Syndrome Research Plan for supplement: The requested administrative supplement for this proposal will increase the hours of current staff to maintain them at a full-time position and | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| GEORGETOWN UNIVERSITY (THE) | $30,700 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Giardia lamblia is the most common protozoan cause of diarrhea in the world. It infects ~500 million people worldwide resulting in nutrient malabsorption which can lead to cognitive developmental defects in children. M | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | $65,068 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Human papillomavirus (HPV) is a sexually transmitted infection and primary cause of anal cancer. While male anal cancer incidence in the US has increased almost threefold in three decades, anal HPV prevalence and risk | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| BRIGHAM YOUNG UNIVERSITY | $42,000 | Grant | Trans-NIH Recovery Act Research Support: Stress within vocal fold tissue is a primary source of vocal fold discomfort and damage. Identifying the influence of various factors that contribute to vocal fold stress can lead to improved clinical care, improved medical procedures, and increased aware | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| SOUTH CAROLINA RESEARCH FOUNDATION | $39,530 | Grant | Trans-NIH Recovery Act Research Support: THROAT CLEARING, COUGHING, AND ALTERNATIVE BEHAVIORS Summary Chronic clearing behaviors are prevalent throughout the population of persons with voice disorders. Throat clearing and coughing have been deemed vocally abusive and are typically targeted to be | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $37,125 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The purpose of this collaborative supplement proposal is to facilitate a new collaborative relationship between the NIDCD funded researchers in Communicative Disorders and researchers in Analytical Chemistry at the U | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF WASHINGTON | $183,484 | Grant | Trans-NIH Recovery Act Research Support: This proposal is in response to Notice Number NOT-OD-09-058: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. The proposed research will examine how the human auditory cortex (AC) responds to combinations of diff | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF NEBRASKA | $73,738 | Grant | Trans-NIH Recovery Act Research Support: Although most children learn to read with relative ease, others have great difficulty. Early reading problems often have a negative impact on later academic and economic advancement, and potentially may reduce quality of life. Research indicates that defi | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| WAKE FOREST UNIVERSITY | $68,720 | Grant | Trans-NIH Recovery Act Research Support: Flexible endoscopic evaluation of swallowing (FEES) has been available, since approximately 1988, to assess patient swallowing function and determine appropriate oral intake. At this stage, FEES is not a novel diagnostic tool; however, what is novel are t | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| SAINT LOUIS UNIVERSITY | $51,076 | Grant | Trans-NIH Recovery Act Research Support: This is an Administrative Supplements (NOT-OD-09-056) for my NIH R15 grant (Application Number: 1 R15 GM086846-01) that was started on December 1, 2008 to study how DME-Interacting Protein 1 regulates demethylation and reproduction in Arabidopsis. | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| THE JACKSON LABORATORY | $43,749 | Grant | Trans-NIH Recovery Act Research Support: This award provided supplemental funding for purchase of equipment from an American microscope manufacturing company to conduct studies needing high resolution imaging. These studies associated with work on the parent award will help us to understand how | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $62,447 | Grant | Trans-NIH Recovery Act Research Support: p16INK4a, Senescence and Aging in Venous Thromboembolism - ARRA The central hypothesis being examined is that an aged-induced increase of p16INK4a expression limits the regenerative capacity of the vascular and hemostasis systems and this increases the r | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| PENNSYLVANIA STATE UNIVERSITY, THE | $40,329 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of this project is to develop ways to interfere with HIV replication and transmission, which would have major implications for preventing the spread of HIV/AIDS. Any successful preventive strategy must work before infection becomes esta | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $159,296 | Grant | Trans-NIH Recovery Act Research Support: These supplemental funds will be used to create a new position for a graduate student who is being added to this project. This student worked part-time on the project over the past year while being supported by a scholarship, and discovered that junctiona | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF ARIZONA | $40,065 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplement is to purchase a Flexivent system for direct measurement of lung function and airway hyperresponsiveness. A Flexivent system will allow increased flexibility in performing experiments yeilding an accelerated pace of research | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $46,448 | Grant | Trans-NIH Recovery Act Research Support: We will investigate combined injury by moderate dose radiation in two models in a two- phase study. In the first phase, we will use anonymized surgical samples irradiated and wounded ex vivo by burning to study gene and protein expression differences, dev | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $63,432 | Grant | Trans-NIH Recovery Act Research Support: For the majority of people with type 2 diabetes mellitus, management of hyperglycemia is improved using a mulit-faceted approach including of weight control and pharmaceutical therapy. The usage of insulin sensitizing drugs thiazolidinediones (TZDs) offer | Health and Human Services, Department of / National Institutes of Health | 6/25/2009 |
| THE MIRIAM HOSPITAL | $252,009 | Grant | Trans-NIH Recovery Act Research Support: There is an important and growing research literature on how exercise interacts with substance use, especially tobacco cessation. However, men are under-represented in this research. This study will substantially expand our ongoing study to include an exp | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| UNIVERSITY OF UTAH, THE | $56,155 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): This proposal is a Competitive Revision request submitted in response to Notice Number (NOT- OD-09-058) entitled NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. Spinal manipu | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | $225,089 | Grant | Trans-NIH Recovery Act Research Support: The use of the prostate specific antigen (PSA) test in the general population and identifiable high-risk subgroups remains controversial, and the PSA test remains the only available test to date to detect early prostate cancer. Because of the controversy, | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH | $91,466 | Grant | Trans-NIH Recovery Act Research Support: This grant allowed the acceleration of health promotion activities to reduce breast cancer disparities in a South Dallas population through the hiring of lay health educators and provision of supplies. | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| WAKE FOREST UNIVERSITY | $13,225 | Grant | Trans-NIH Recovery Act Research Support: This award allowed the hiring of two highly-qualified undergraduate students interested in public health research. During their eight-week summer experience, the students participated in a variety of activities associated with the parent grant G?Measuring | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON | $41,436 | Grant | Trans-NIH Recovery Act Research Support: In Program Announcement PA-06-183: 'HEALTH DISPARITIES IN NIDDK DISEASES,' The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) seeks research to understand and mitigate issues of health disparities in high priority diseases within | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| CASE WESTERN RESERVE UNIVERSITY | $62,313 | Grant | Trans-NIH Recovery Act Research Support: The goal of this R21 application is to develop a three-dimensional (3D) model of the glomerular filtration barrier that incorporates the key cellular components, podocytes and endothelial cells, and matrix that models the glomerular basement membrane (GBM | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF WASHINGTON | $33,941 | Grant | Trans-NIH Recovery Act Research Support: Developing systems capable of controlled and efficient gene transfer is essential to both basic science and clinical medicine. In the area of basic science, modulating a gene within a cell has the power to reveal or confirm the roles of specific component | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| OREGON STATE UNIVERSITY | $74,832 | Grant | Trans-NIH Recovery Act Research Support: Polycyclic aromatic hydrocarbons (PAHs), including benzo(a)pyrene (BP), form a major class of environmental pollutants suggested to be causative factors in a variety of disease susceptibilities, including cancer. Virtually all PAH mixtures contain BP; a m | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF CINCINNATI | $113,868 | Grant | Trans-NIH Recovery Act Research Support: The incidence of obesity has risen dramatically over the last few decades. In addition to high caloric food intake and sedentary life style, the role of environmental factors is gaining credence. Bisphenol A (BPA) is a monomer of polycarbonate plastics us | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| PURDUE UNIVERSITY | $35,740 | Grant | Trans-NIH Recovery Act Research Support: Accumulation of beta-amyloid (Ab) in brain extracellular fluids is the key event in the amyloid cascade leading to neuronal cell damage in the etiology of Alzheimer's disease (AD). Our preliminary data suggest that the choroid plexus sequesters Ab from th | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | $150,859 | Grant | Trans-NIH Recovery Act Research Support: The photoreceptor cells of the retina carry out the essential task of translating light into electrical signals that can be passed on and analyzed by the rest of the visual system. Diseases that cause the photoreceptor cells to degenerate lead to irrevers | Health and Human Services, Department of / National Institutes of Health | 9/12/2009 |
| DUKE UNIVERSITY | $115,689 | Grant | Trans-NIH Recovery Act Research Support: Trabecular meshwork cells are known to be actively phagocytic; they are capable of ingesting endogenous and exogenous material, thus keeping the trabecular outflow channels free of potentially obstructive debris. During the experimental phase of SA.1 of t | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| REHABILITATION INSTITUTE OF CHICAGO | $87,366 | Grant | Trans-NIH Recovery Act Research Support: This award is issued in response to Notice OD-09-060, Recovery Act Administrative Supplements Providing Summer Research Experiences for Students and Science Educators. The goal of this project is to design and develop a hand exoskeleton to facilitate reha | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $39,832 | Grant | Trans-NIH Recovery Act Research Support: ARRA - Community Participation Research of Breastfeeding Disparities in African. Project Description: The resources provided allowed for several important project enhancements: 1. The parent grant provided us with sufficient resources to survey individual | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF HAWAII SYSTEMS | $6,664 | Grant | Trans-NIH Recovery Act Research Support: The primary goal of this application is to use itracytoplasmic sperm (ICSI) and other assisted reproduction techniques (ART) to define the minimum Y gene requirement during spermatogenesis that is compatible with the generation of ART-competent sperm. | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| UMDNJ-ROBERT WOOD JOHNSON MEDICAL SCHOOL | $115,873 | Grant | Trans-NIH Recovery Act Research Support: An Administrative Supplement under the American Recovery and Reinvestment Act of 2009 was requested to enhance the education and research of trainees supported by Initiative for Maximizing Student Diversity Award 2R25 GM055145. Three components include: | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $190,598 | Grant | Trans-NIH Recovery Act Research Support: Initiative for Minority Student Development at UNC-Chapel Hill-ARRA funds will enhance the academic support and success of IMSD graduate students through enhanced academic tutoring, scientific writing training, biostatistical support and professional and | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| LOMA LINDA UNIVERSITY | $206,292 | Grant | Trans-NIH Recovery Act Research Support: The mission of the National Institutes of Health is to improve the health status of all Americans through biomedical research and scientific training and education. To reach this goal we need to succeed in developing a diverse group of scientists ready to | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF NORTH CAROLINA AT PEMBROKE | $216,944 | Grant | Trans-NIH Recovery Act Research Support: In line with the goals of ARRA, this requested supplement will provide monies to: 1) create new jobs that facilitate the continued growth of the University's research training program, as will the increased support for faculty direction of summer research | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF KANSAS CENTER FOR RESEARCH, INC. | $39,186 | Grant | Trans-NIH Recovery Act Research Support: Over the past six years, a partnership between Haskell Indian Nations University and the University of Kansas has been forged to achieve the goal of bringing more American Indians into the biomedical research community. With support from the NIGMS MORE pr | Health and Human Services, Department of / National Institutes of Health | 8/27/2009 |
| UNIVERSITY OF NORTH CAROLINA AT PEMBROKE | $61,731 | Grant | Trans-NIH Recovery Act Research Support: This supplement will provide additional funding to increase the accomplishments of the Bridges program between UNCP and its three community college partners, Robeson Community College (RCC), Bladen Community College (BCC), and Brunswick Community College | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| NORTH CAROLINA STATE UNIVERSITY | $112,363 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this administrative supplement to the NC State Initiative for Maximizing Student Diversity (IMSD) Program is to increase and extend the science and training opportunities to IMSD students. Funds from the supplement will allow the program | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF TENNESSEE | $207,242 | Grant | Trans-NIH Recovery Act Research Support: This award is a supplement to an R25 training grant for graduate education in STEM disciplines at the University of Tennessee. The parent program is called the 'Program for Excellence and Equity in Research.' A primary objective is to increase the parti | Health and Human Services, Department of / National Institutes of Health | 8/25/2009 |
| UNIVERSITY OF WASHINGTON | $80,051 | Grant | Trans-NIH Recovery Act Research Support: The overarching aim of the parent grant of this project is to develop, evaluate, and disseminate a clinician-scientist training Program of Excellence in Dialectical Behavior Therapy. This is being accomplished by enhancing the existing DBT clinical-scient | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF HAWAII SYSTEMS | $296,612 | Grant | Trans-NIH Recovery Act Research Support: We seek to formalize and implement a clinical research training program leading to a Master of Science at the University of Hawaii for selected medical students, residents and fellows, post-doctoral fellows, PhD candidates, and junior faculty members. Par | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| UNIVERSITY OF MONTANA SYSTEM | $185,760 | Grant | Trans-NIH Recovery Act Research Support: The overarching goal of this administrative supplement is to expand those activities that we have found, through experience and evaluation in our parent SEPA grant, to be effective in increasing students' understanding of environmental health science conc | Health and Human Services, Department of / National Institutes of Health | 8/12/2009 |
| UNIVERSITY OF MIAMI | $206,372 | Grant | Trans-NIH Recovery Act Research Support: The supplemental request expanded on two of the parent grantG??s objectives: 1. To investigate the extent to which a museum-based health exhibit and related classroom resource can lead to gains in high school studentsG?? knowledge about cardiovascular h | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF HAWAII SYSTEMS | $188,708 | Grant | Trans-NIH Recovery Act Research Support: The goal of the Pacific Education and Research for Leadership in Science (PEARLS) project is to improve knowledge of science and scientific research, while increasing interest in science careers by introducing an innovative science curriculum for middle/i | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF TEXAS AT DALLAS | $894,213 | Grant | Trans-NIH Recovery Act Research Support: This proposal is a response to NOT-OD-058, 'NIH Announces the Availability of Recover Act Funds for Competitive Revision Applications.' It utilizes new neuroimaging advances (including amyloid imaging) that were not even available to the project at the ti | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF FLORIDA | $89,664 | Grant | Trans-NIH Recovery Act Research Support: The overall purpose of our research project is to understand the consequences of drug resistance mutations on the properties and structure of the HIV-1 protease. This is a major drug target for treatment of HIV-1 infected humans and inhibitors of this enz | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| NEW YORK UNIVERSITY (INC) | $361,112 | Grant | Trans-NIH Recovery Act Research Support: Although the institution of anti-retroviral therapy (ART) has reduced morbidity and mortality from HIV infection, immune reconstitution is incomplete, virus persists in tissue reservoirs and rebound viremia occurs when treatment is halted. Recent findings | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF CHICAGO, THE | $70,100 | Grant | Trans-NIH Recovery Act Research Support: The 775 residue infected cell protein No.O (ICPO) of herpes simplex virus 1 (HSV-1) is amultifunctional protein known primarily as a promiscuous transactivator. Studies initiated during the previousgrant period demonstrated that it contains ubiquitin liga | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| CEDARS-SINAI MEDICAL CENTER | $105,625 | Grant | Trans-NIH Recovery Act Research Support: IFN-y plays an important role in the generation and perpetuation of mucosal inflammation in many animal models of inflammatory bowel disease (IBD) and is central to the induction and perpetuation of Crohn's disease (CD). Cytokines indicative of Th1 polari | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $100,952 | Grant | Trans-NIH Recovery Act Research Support: Lactoccocus lactis expression of Mrs3 and Mrs4 yeast mitochondrial carrier proteins and assessment of their iron transport activities in whole cells or liposomes. In the original proposal all studies of iron transport and the roles of mitochondrial carrie | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| ST. JUDE CHILDREN'S RESEARCH HOSPITAL | $70,800 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of this project is to understand the mechanisms that regulate bacterial membrane lipidbiosynthesis and explore the structure, function and diversity of the enzymes involved in this pathway. The studyof Escherichia coli has historically | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $33,000 | Grant | Trans-NIH Recovery Act Research Support: The overall goals of the research supported by the parent grant (GM47365) are to obtain fundamental chemical insights into copper protein structure and function through the synthetic modeling approach, wherein low molecular weight complexes designed to be | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $123,435 | Grant | Trans-NIH Recovery Act Research Support: The project is directed toward the development of technology for cloning mice from fibroblasts. This will permit us to recover mice that die as a result of conditionally lethal phenotypes, such as hypersensitivity to lPS. The deliverables are cloned mice | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $568,560 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): This project aims to develop, improve, and exploit new molecules, mostly genetically targetable, for measuring and/or manipulating neuronal messengers and signals such as calcium, glutamate, GABA, action potentials, su | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| IMMERSIVETOUCH, INC. | $247,600 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): ImmersiveTouch Inc. develops innovative augmented virtual reality software SENSIMMER} for surgical training of residents in such fields as neurosurgery and ophthalmology. In collaboration with the University of Illinoi | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| NAPROGENIX, INC. | $10,000 | Grant | Trans-NIH Recovery Act Research Support: Title: Potential anti-relapse drugs: a plant genomics approach Description: Student to work research project as described as follows: Glutamate/NMDA (NMDARs) and nicotinic receptors (nicAChRs) in the CNS are accepted targets for antirelapse drugs. The ori | Health and Human Services, Department of / National Institutes of Health | 8/15/2009 |
| RATIONAL AFFINITY DEVICES, INC | $6,250 | Grant | Trans-NIH Recovery Act Research Support: The proposed funding will supplement the SBIR grant # R43 AI 074089, the goal of which is to develop a diagnostic device that will provide an inexpensive, robust and precise means of rapidly diagnosing and profiling S. aureus infections with respect to an | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| GENOME DATA SYSTEMS INC | $86,542 | Grant | Trans-NIH Recovery Act Research Support: This application proposes a novel approach to address the highly significant problem of microarray signal variation. Future advances in human health will that use knowledge gained from whole genome molecular analysis. Whole genome expression analysis usin | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| ICOGENEX CORPORATION | $9,335 | Grant | Trans-NIH Recovery Act Research Support: This grant provided a summer research experience for a college student in health-related scientific research. | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| SOURCE PRODUCTION AND EQUIPMENT COMPANY, INC. | $200,000 | Grant | Trans-NIH Recovery Act Research Support: Project summary as stated in the application. This phase II program is developing an improved brachytherapy delivery system for treatment of lung cancer by incorporating radioactive 169 Ytterbium sources into surgical staples used in lung resection. This | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| VALA SCIENCES INC. | $37,200 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the ARRA Administrative Supplement Providing Summer Research Experiences, which was awarded to Vala Sciences Inc, was to support the research being conducted at Vala for the NIH SBIR project 3R44DK074333 HT Image Assay of Lipid Droplet Form | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| DUKE UNIVERSITY | $464,942 | Grant | Trans-NIH Recovery Act Research Support: This application, to be supported for 1 year with bridge funds from ARRA, explores the long term outcomes of thymus transplantation. Over the last 15 years, our laboratory has established that thymus transplantation is a successful therapeutic strategy f | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| CREIGHTON UNIVERSITY | $361,250 | Grant | Trans-NIH Recovery Act Research Support: The ARRA funded project is a one year extension of an R56 grant intended to provide bridging support for my NIH-funded research program while we work to renew my existing NIH R01 research project and/or obtain new NIH funding. The focus of my research pr | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $428,793 | Grant | Trans-NIH Recovery Act Research Support: Shigella is a major cause of diarrhea, dysentery, and mortality annually worldwide. S. flexneri is a CDC/NIAID Category B priority pathogen. It causes disease by invading and spreading through the colonic mucosa. The bacteria enter cells by inducing a pro | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $7,264 | Grant | Trans-NIH Recovery Act Research Support: The proposed studies will further elucidate mechanisms of matrix protein self-assembly in enamel and as such provide important information for understanding enamel formation on the molecular and nanometer scale. | Health and Human Services, Department of / National Institutes of Health | 6/02/2009 |
| SCHEPENS EYE RESEARCH INSTITUTE, INC., THE | $18,841 | Grant | Trans-NIH Recovery Act Research Support: One undergraduate student, in an 11 week project, will compile backseat rater score sheets for four of our existing simulator drives then pilot-test the sheets by scoring the driving skills of normally-sighted and visually impaired people as they drive i | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| NORTHEASTERN UNIVERSITY | $204,819 | Grant | Trans-NIH Recovery Act Research Support: Separation and analytical Technologies for Proteomics | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| CHARLES DREW UNIVERSITY OF MEDICINE AND SCIENCE | $249,068 | Grant | Trans-NIH Recovery Act Research Support: The Drew MBRS SCORE program's overall mission is to significantly improve the quality of biomedical research and to increase the long-term growth of competitive funding at Charles R. Drew University of Medicine and Science. Current MBRS-SCORE funding (fun | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| UNIVERSITY OF WASHINGTON | $622,739 | Grant | Trans-NIH Recovery Act Research Support: The major goal will be to identify, characterize and study those drugs that are of therapeutic value during pregnancy and whose clinical pharmacology (both pharmacokinetic and pharmacodynamic) is altered by the pregnant state. Despite the fact that the av | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE | $700,728 | Grant | Trans-NIH Recovery Act Research Support: Food allergy has become a major health problem in westernized countries and now affects 3.5% - 4% of the U.S. population with cow's milk allergy [CMA] affecting 2.5% of young children. CMA provides an ideal model to study immunologic mechanisms responsibl | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO | $547,218 | Grant | Trans-NIH Recovery Act Research Support: The San Antonio Sexually Transmitted Infections & Topical Microbicides Cooperative Research Center (STI TM CRC) proposal represents an integrative, collaborative and innovative multi-disciplinary research effort to investigate and prevent important emergi | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF ROCHESTER | $600,601 | Grant | Trans-NIH Recovery Act Research Support: B cell signatures in SLE - Justification: Provide the best and most extensive clinical and immunological characterization of any Lupus cohort and will extend the ACE studies. Longitudinal 2-year follow-up of 250 Lupus patients (3x/year for a total of 1,5 | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| EMORY UNIVERSITY | $2,462,810 | Grant | Trans-NIH Recovery Act Research Support: Vaccine Induced Immunity in the Young and Aged: The novel H1N1 influenza virus caused a pandemic that clearly demonstrated the global health threat of reassortant influenza strains. This newly emergent strain is immunologically distinct from other influen | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| DUKE UNIVERSITY | $400,000 | Grant | Trans-NIH Recovery Act Research Support: The broad and long term objectives of this research application focuses on rapid biodosimetry and mitigation of radiation injury as well as advancing education in this area. Many individuals believe that the single greatest threat to America is nuclear pr | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $593,352 | Grant | Trans-NIH Recovery Act Research Support: The scope of this ancillary is to validate DNA biomarkers associated with kidney transplant outcomes in other studies such as the projects funded by the Genomics of Transplantation Cooperative Research Program. | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| MANAGEMENT ANALYSIS, INCORPORATED | $100,000 | Contract | : This task order is awarded to provide specialized expertise in grants regulatory and policy compliance to support implementation of required NIH oversight for ARRA funded grants. | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| RANGER GROUP LLC, THE | $3,967,179 | Contract | : 'Recovery Act' -- Repair & Upgrade Switchgear -- Building 13S | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| RANGER GROUP LLC, THE | $4,083,561 | Contract | : 'Recovery Act' -- Repair & Upgrade Switchgear -- Building 31C | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $3,342,419 | Grant | Trans-NIH Recovery Act Research Support: This is competing continuation proposal for Years 17-22 of the Health and Retirement Study (HRS). We propose to continue core data collection on the steady-state design laid out in the previous renewal, including the addition of a new cohort in 2010; to b | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $142,919 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): This proposal is for a 5 year renewal (years 16-20) of the Alzheimer's Disease Cooperative Study (ADCS). This consortium of 34 members' sites and 46-56 participating sites is proposing both continued instrument develop | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| UNIVERSITY OF PITTSBURGH THE | $288,855 | Grant | Trans-NIH Recovery Act Research Support: This is a supplement to fund the systematic coding of medication data collected in the Study of Women's Health Across the Nation (SWAN) and the creation of datasets to streamline analyses to improve scientific productivity. In addition, the medication da | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| KUAKINI MEDICAL CENTER | $960,480 | Grant | Trans-NIH Recovery Act Research Support: Our application is in response to NOT-OD-09-058: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. The parent grant is 5U01AG017155-08, Epidemiology of Aging and Dementia-Autopsy Research. We will address three | Health and Human Services, Department of / National Institutes of Health | 9/02/2009 |
| MAYO CLINIC | $759,405 | Grant | Trans-NIH Recovery Act Research Support: The Mayo Clinic CTSA is in the process of transforming the Mayo Clinic Biomedical Mass Spectrometry facility into a Metabolomics Core. This will fill a gap in our novel technology facilities at Mayo Clinic and will substantially strengthen translational r | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF ROCHESTER | $598,483 | Grant | Trans-NIH Recovery Act Research Support: The project proposes to establish, in collaboration with the Morehouse School of Medicine (MSM) the RICE (Research in Comparative Effectiveness) Network, a practice-based research network (PBRN) specializing in comparative effectiveness research (CER). Th | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF ROCHESTER | $299,036 | Grant | Trans-NIH Recovery Act Research Support: This project will expand the content on CTSpedia to include additional encyclopedic articles, statistical tools for analysis, and editable and freely shared articles of course materials. With the funding from this project, we also propose to continue to | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF PITTSBURGH THE | $699,574 | Grant | Trans-NIH Recovery Act Research Support: Funding for this protocol is to allow enrollment of an additional group of patients who have malignancies that are positive for BRCA mutations. Specific Aims This protocol will evaluate the combination chemotherapy regimen of the PARP inhibitor ABT-888 in | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| WAYNE STATE UNIVERSITY | $199,883 | Grant | Trans-NIH Recovery Act Research Support: The determine the CNP for older underserved African American adults. | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| DANA-FARBER CANCER INSTITUTE, INC. | $336,232 | Grant | Trans-NIH Recovery Act Research Support: Overweight and obesity disproportionately affect racial and ethnic minority and lower income populations, particularly women. An accumulating body of scientific evidence indicates that obesity, sedentary lifestyles, and unhealthy dietary patterns may sign | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $607,827 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement application proposes the development of an innovative clinical trialscurriculum (CTC) designed to enhance the research training, education, and career development componentof the University of Pennsylvania s (Penn) Clinical | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $599,998 | Grant | Trans-NIH Recovery Act Research Support: This request for supplemental funding provides an excellent opportunity to address the OCTRI Community Research and Engagement Specific Aim 3 of G?build[ing] and alliance between communities and researchers that will foster public trust and engagement and | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| CHILDREN'S MEMORIAL HOSPITAL, THE | $231,019 | Grant | Trans-NIH Recovery Act Research Support: Congenital heart malformations are among the most prevalent and serious diseases, and in many cases they are life threatening. Certain gene regulators, so called Tbx transcription factors, have been implicated in a number of complex cardiovascular defects | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF MISSOURI SYSTEM | $2,071,452 | Grant | Trans-NIH Recovery Act Research Support: The goal of this project is to develop a mouse-human chimeric model with a vascular endothelium and a hematopoietic system derived from human induced pluripotent stem (iPS) cells while all other tissues and organs will be from a mouse. Previous reports h | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| FOUNDATION FOR THE CALIFORNIA STATE UNIVERSITY, SAN BERNARDINO | $98,267 | Grant | Trans-NIH Recovery Act Research Support: The goal of the proposed administrative supplement is to enhance the research enviornment at CSUSB by increasing the productivity of the CSUSB faculty members engaged in biomedical and behavioral research. We propose to purchase state of the art equipmen | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| CHARLES DREW UNIVERSITY OF MEDICINE AND SCIENCE | $184,768 | Grant | Trans-NIH Recovery Act Research Support: Testosterone (T) supplementation increases muscle mass and decreases fat mass in a variety of clinical trials using healthy young men, hypogonadal men, and in older men with low serum T levels. However, the molecular mechanisms by which T regulates body c | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| RFCUNY - HUNTER COLLEGE | $195,366 | Grant | Trans-NIH Recovery Act Research Support: Research Enhancement Award: Individual investigator-initiated research projects aimed at developing researchers at minority-serving institutions (MSIs) to a stage where they can transition successfully to other extramural support (R01 or equivalent). | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| HOWARD UNIVERSITY, INC. | $206,000 | Grant | Trans-NIH Recovery Act Research Support: The supplement funding will allow the purchase of a high quality Olympus IX51 inverted microscope with reflected light fluorescence and a color digital camera. This equipment will enhance and augment Research capabilities of the Center for Sickle Cell Dis | Health and Human Services, Department of / National Institutes of Health | 9/10/2009 |
| CAL POLY POMONA FOUNDATION INC | $39,283 | Grant | Trans-NIH Recovery Act Research Support: Our long-term objective is to gain a comprehensive understanding of the molecular mechanism by which gamma-aminobutyric acid (GABA) transporters accomplish cotransport across the plasma membrane. The GABA transporters transport GABA into cells after its r | Health and Human Services, Department of / National Institutes of Health | 9/10/2009 |
| CHARLES DREW UNIVERSITY OF MEDICINE AND SCIENCE | $95,880 | Grant | Trans-NIH Recovery Act Research Support: Recent evidence demonstrates that the functional impairment or atrophy of pelvic muscles, such as levator ani, urethral supports and urethral sphincter, are responsible for stress urinary incontinence (SUI) in women. SUI is a common condition with signifi | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| NORTH CAROLINA CENTRAL UNIVERSITY | $220,272 | Grant | Trans-NIH Recovery Act Research Support: The goal is to increase the research productivity of the project, by providing additional fund to hire a research associate that was partially funded in the parent proposal, and to provide vital multiuser equipments that would facilitate the implementatio | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| NEW MEXICO STATE UNIVERSITY | $55,644 | Grant | Trans-NIH Recovery Act Research Support: Award is aimed to achieve enhancement in the process and productivity of the on-going project that seeks to identify the source of hydrogen peroxide that accompanies pathogen invasion in eukaryotic cells. Supplemental funding to hire additional part-time | Health and Human Services, Department of / National Institutes of Health | 6/01/2008 |
| UNIVERSITY OF PUERTO RICO-MEDICAL SCIENCES CAMPUS | $110,035 | Grant | Trans-NIH Recovery Act Research Support: The objective of this supplement is to advance the pace of the discovery , identification and characterization of the peptides that appear to show distinctive expression as compared to mormal patients.Our first aim is to retain as full time personnel a ve | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| SAN JOSE STATE UNIVERSITY FOUNDATION INC | $98,702 | Grant | Trans-NIH Recovery Act Research Support: The proposed work will evaluate the potential for pursuing inositol glycans or analogues as therapeutic agents for cancer. Preliminary work has demonstrated that a fatty-acylated inositol glycan (IG) selectively kills a variety of cancer cell types in cul | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | $131,000 | Grant | Trans-NIH Recovery Act Research Support: The Stony Brook University Genetics Program is a graduate educational and research program leading to the Ph.D. degree in Genetics. The Genetics Program provides a unique, multi-institutional curriculum of course and laboratory research that draws upon th | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY | $157,500 | Grant | Trans-NIH Recovery Act Research Support: The objective of the Molecular and Cell Biology (MCB) Training Program, for which this application is seeking renewal of support, is to provide an unsurpassed body of scientific and academic training in molecular and cell biology to individuals who will b | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $139,452 | Grant | Trans-NIH Recovery Act Research Support: This pre-doctoral training program at the Chemistry-Biology Interface involves 29 training faculty from three departments at the University of Minnesota: Chemistry, Medicinal Chemistry, and Biochemistry, Molecular Biology and Biophysics (BMBB). It seeks t | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF IOWA, THE | $63,964 | Grant | Trans-NIH Recovery Act Research Support: The principal goal of this training grant (TG) is to promote the interdisciplinary training of graduate students in Pharmacological Sciences. Its secondary goal is to foster interactions among faculty and students from different Departments that share an | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF ILLINOIS | $38,310 | Grant | Trans-NIH Recovery Act Research Support: This is a 1 year ARRA-funded supplement to our NIH-awarded training grant number 5 T32 GM070388-05, which funds PhD training and research in Pharmacological Sciences. In the spirit of ARRA goals, these additional funds were used for a new appointment ( | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $91,308 | Grant | Trans-NIH Recovery Act Research Support: INTERDISCIPLINARY RESEARCH TRAINING IN BIOSTATISTICS This training program is designed to develop a cadre of young scientists who can participate at the intersection of biostatistics, epidemiology, and molecular biology to become leaders in integrative an | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| CALIFORNIA STATE UNIVERSITY, BAKERSFIELD | $78,775 | Grant | Trans-NIH Recovery Act Research Support: This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This award provides funding for equipment purchases to supplement the standing MARC U*STAR program at California State University, Bakersfield. Microscopes, | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| MED STAR HEALTH RESEARCH INSTITUTE | $214,061 | Grant | Trans-NIH Recovery Act Research Support: Provide an infrastructure to address the unique cancer control needs of the Latinos of Central and South American ancestry in our area. Overarching goal of LACRC's regional network is to document, understand, and reduce cancer disparities in the growing L | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| HEKTOEN INSTITUTE FOR MEDICAL RESEARCH, THE | $111,392 | Grant | Trans-NIH Recovery Act Research Support: Since the inception of funding, qualitative and quantitative data, including autobiographical narratives and several self-report measures of gender roles, have been collected for 85 WIHS Chicago participants. Based on analyses of the coded narratives and | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| HOWARD BROWN HEALTH CENTER | $1,076,010 | Grant | Trans-NIH Recovery Act Research Support: This recovery act administrative supplement to the Multicenter AIDS Cohort Study (MACS) will support work to elucidate the role played by microbial translocation in immune activation and CD4+ T cell homeostasis. Chronic activation of the immune system is | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE | $920,550 | Grant | Trans-NIH Recovery Act Research Support: Transplantation is the ideal therapy for end stage heart and end stage kidney failure, but allograft survival and function remain suboptimal. This CTOT renewal application will build upon the findings resulting from the previous 4 years of studying biomar | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $2,144,799 | Grant | Trans-NIH Recovery Act Research Support: Transplantation is widely recognized as the treatment of choice for end stage organ failure. While short-term allograft survival has been steadily improving, long-term survival is still not optimal. Most grafts will eventually cease to function, primarily | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE | $371,823 | Grant | Trans-NIH Recovery Act Research Support: This CER proposal will examine a head-to-head comparison of different surgical options as they are practiced in the community for older women across three points in the continuum of care: detection, diagnosis and surgical treatment. Our four aims are: 1. | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $331,524 | Grant | Trans-NIH Recovery Act Research Support: Phase I studies play a critical role in the development of new cancer therapies. These trials are the initial interface between basic and clinical research for 'first in human' studies. Successful therapeutic research embodies an iterative process between | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| AMERICAN COLLEGE OF RADIOLOGY, THE | $750,000 | Grant | Trans-NIH Recovery Act Research Support: American College of Radiology Imaging Network (ACRIN) 6684: Multicenter phase II assessment of tumor hypoxia in glioblastoma using 18F-flouromisonidazole (FMISO) with PET and MRI. This trial will use PET and MRI techniques hand in hand to monitor the sta | Health and Human Services, Department of / National Institutes of Health | 7/30/2009 |
| NATIONAL CHILDHOOD CANCER FOUNDATION | $233,108 | Grant | Trans-NIH Recovery Act Research Support: This award supports the Development of Multi-site Functional Neurocognitive and Behavioral Assessments within Children's Oncology Group (COG) to ensure Stable Measures for More Informed Phase III Clinical Trials. The Behavioral Science Committee (BSC) of | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| UNIVERSITY OF PITTSBURGH THE | $749,856 | Grant | Trans-NIH Recovery Act Research Support: Funding for this protocol is to allow enrollment of an additional group of patients who have malignancies that are positive for BRCA mutations. Specific Aims: This protocol will evaluate the combination chemotherapy regimen of the PARP inhibitor ABT-888 | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | $663,994 | Grant | Trans-NIH Recovery Act Research Support: In response to an urgent need to create solutions for the development of efficacious cancer interventions for the effective penetration within the community, H. Lee Moffitt Cancer Center & Research Institute at the University of South Florida, in collabor | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $306,083 | Grant | Trans-NIH Recovery Act Research Support: This study will enable us to increase the Asian American community capacity for understanding the value of biospecimen contributions for research. This capacity will be particularly enhanced as we intend to go beyond the assessment and production of Engli | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF MARYLAND | $99,554 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement supports ARRA goals for equipment purchase of an IVR System to support conduct of cancer health disparities research and training of junior investigators on CHD research methods Skills gained will be relevant for career deve | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO | $216,898 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the administrative supplement is to conduct ?Salud Hidalgo?, a project designed to promote cancer control prevention among predominately low-income Latinos living in Hidalgo county, Texas, situated on the U.S.-Mexico border.?Salud-Hidalgo? | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| NORTHWESTERN UNIVERSITY | $67,710 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplement is to provide the opportunity for 3 high school and 3 undergraduate college students to work in a summer research experience and participate in existing unique and focused cancer educational initiatives. | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| WAKE FOREST UNIVERSITY | $598,465 | Grant | Trans-NIH Recovery Act Research Support: Look AHEAD is a multi-center randomized clinical trial to determine the long-term impact of weight loss on cardiovascular morbidity and mortality in over 5000 overweight individuals with type 2 diabetes. Participants were randomly assigned to an intensiv | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| BAYLOR COLLEGE OF MEDICINE | $117,900 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the supplement is to maximize study retention and to amplify the effects of the lifestyle intervention and to retain staff positions. The Administrative Supplement to Look AHEAD will increase the scientific impact of Look AHEAD and retain | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE | $103,687 | Grant | Trans-NIH Recovery Act Research Support: Glucotoxicity, lipotoxicity, advanced glycation end products (AGE), and reactive oxygen species (ROS) have emerged as important mediators of diabetes-induced tissue injury. However, the precise cellular targets and molecular mechanisms by which these medi | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| CASE WESTERN RESERVE UNIVERSITY | $120,472 | Grant | Trans-NIH Recovery Act Research Support: G?The Chronic Renal Insufficiency Cohort study is a longitudinal observational study of patients with chronic kidney disease. An important goal of the study is is evaluate the relationship between kidney function and cardiovascular disease. To accomplish | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $300,816 | Grant | Trans-NIH Recovery Act Research Support: The HALT-PKD study is the first prospective clinical interventional study for autosomal dominant polycystic disease (ADPKD). The goal of the HALT PKD study is to slow or prevent the progression of the kidney and heart disease in patients with early (Study | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| MAYO CLINIC | $423,547 | Grant | Trans-NIH Recovery Act Research Support: This is an ARRA Administrative Supplement proposal for U01DK062410 Polycystic Kidney Disease-Treatment Network (HALT PKD): Controlled Trials of Renin Angiotensin Blockade in Autosomal Dominant Polycystic Kidney Disease (ADPKD). The Mayo Clinic (with subco | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF CINCINNATI | $349,722 | Grant | Trans-NIH Recovery Act Research Support: Arteriovenous (AV) fistula non-maturation is currently a huge clinical problem and a major cause of morbidity and increased costs in the hemodialysis population. Although AV fistulae are the preferred mode of dialysis access they have a very high incidenc | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| UNIVERSITY OF WASHINGTON | $5,288 | Grant | Trans-NIH Recovery Act Research Support: The requested supplement will allow an undergraduate student to gain exposure to a laboratory research environment and permit senior investigators more time to deal with or accelerate other aspects of the project (molecular modeling and cell studies). Du | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $46,273 | Grant | Trans-NIH Recovery Act Research Support: Summer research training will be provided to high school students, undergraduate, and high school science science educators interested in contraceptive target identification, validation and drug development. Each of the four laboratories involved in this | Health and Human Services, Department of / National Institutes of Health | 6/19/2009 |
| HENRY M JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY M | $10,000,000 | Grant | Trans-NIH Recovery Act Research Support: This ARRA supplement under the parent U01 grant was funded to expand the original parent U01 scope of work. Based on our earlier meetings with NIMH and the US Army, the focus of this study was expanded in five ways: (i) the range of outcomes assessed; (i | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| SMITHSONIAN INSTITUTION | $12,033 | Grant | Trans-NIH Recovery Act Research Support: The over-arching goal of this work is to discover new lead compounds from Panamanian microorganisms for the treatment of cancer, CNS disorders, tropical diseases, and agricultural pests, employing a spectrum of innovative as well as traditional bioassays. | Health and Human Services, Department of / National Institutes of Health | 6/02/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $1,349,862 | Grant | Trans-NIH Recovery Act Research Support: This two-year study will utilize a randomized design with the active interventions running for 18 months. We have 26 active US sites (27 approved sites with one having to drop out due to lack of indirect cost recovery to pay IRB costs). The 26 sites will | Health and Human Services, Department of / National Institutes of Health | 8/19/2009 |
| UNIVERSITY OF CHICAGO, THE | $201,363 | Grant | Trans-NIH Recovery Act Research Support: The CALGB is comprised of 26 academic medical centers and over 200 affiliated community hospitals joined in the pursuit of improved cancer treatment and better understanding of tumor biology and cancer treatment outcomes via the conduct of controlled clin | Health and Human Services, Department of / National Institutes of Health | 7/26/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $779,775 | Grant | Trans-NIH Recovery Act Research Support: The Southwest Oncology Group is an adult, multi-disease, multi-modality clinical cancer research organization with 35 Member Institutions, 29 Community Clinical Oncology Program (CCOP) institutions, including 7 Minority-Based CCOPs, 27 Urologic Cancer Out | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| MARSHFIELD CLINIC | $298,811 | Grant | Trans-NIH Recovery Act Research Support: The Marshfield Clinic (MC) Community Clinical Oncology Program (CCOP) has consistently provided its patients unprecedented opportunities to participate in state-of-the-art clinical trials with the goal of improving the quality of life in cancer patients s | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| LOUISIANA STATE UNIVERSITY SYSTEM | $751,419 | Grant | Trans-NIH Recovery Act Research Support: The supplement allows three collaborating units to increase accruals of minority and underserved populations into cancer clinical trials by 1) Enabling two community clinical oncology programs (CCOPs) to hire new staff to increase recruitment into trials, | Health and Human Services, Department of / National Institutes of Health | 9/08/2009 |
| DUKE UNIVERSITY | $106,834 | Grant | Trans-NIH Recovery Act Research Support: The American College of Surgeons Oncology Group (ACOSOG) is dedicated to improving the care of the surgical oncology patient through an innovative clinical research program addressing three specific aims: 1. To test novel therapies that may increase respo | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $1,048,712 | Grant | Trans-NIH Recovery Act Research Support: The Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error (CLEERE) Study is an expansion of the Orinda. Longitudinal Study of Myopia (OLSM). The original, single-center study started in Orinda, California in 1989, and the three CLEERE cl | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| DUKE UNIVERSITY | $576,978 | Grant | Trans-NIH Recovery Act Research Support: The primary objective of the activities proposed in this application is to provide optical coherence tomography (OCT) Reading Center support to the Comparison of Age Related Macular Degeneration Treatment trials (CATT). The long term goals of this project | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| PENNSYLVANIA STATE UNIVERSITY, THE | $274,042 | Grant | Trans-NIH Recovery Act Research Support: This is a competing renewal of the Penn State College of Medicine RMN Unit. We have contributed significantly to the productivity of the RMN in the prior funding cycle as a major recruiting site and developer of protocols. Dr. Legro's concept protocol fro | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $233,551 | Grant | Trans-NIH Recovery Act Research Support: The Pelvic Floor Disorders Network (PFDN) is a cooperative multi-center network of clinical sites and a Data Coordinating Center (DCC) directed by a Steering Committee composed of the principal investigators of the clinical sites and DCC and the NIH Proje | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $852,000 | Grant | Trans-NIH Recovery Act Research Support: Immunobiology of Acute Environmental Asthma - ARRA The objective of our parent grant, !The immunobiology of acute environmental asthma,! is to determine the role of several recently discovered innate immune molecules in the pathogenesis of asthma. These | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| MAYO CLINIC | $222,055 | Grant | Trans-NIH Recovery Act Research Support: The Colon Cancer Family Registry (C-CFR) is an international consortium that provides a comprehensive collaborative infrastructure for studies of the genetics and epidemiology of colorectal cancer (CRC). The CCFR was founded by NCI in 1997 as a UO1 under | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| GYNECOLOGIC ONCOLOGY GROUP , THE | $543,182 | Grant | Trans-NIH Recovery Act Research Support: The Gynecologic Oncology Group (GOG) is the premier clinical trial research program investigating new therapeutic approaches in the management of gynecologic malignancies. This multidisciplinary, multimodal Group comprises over 200 participating universit | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $595,841 | Grant | Trans-NIH Recovery Act Research Support: The optimal treatment of chronic diseases represents a major challenge, including overcoming barriers such as access to health care. This proposal addresses the growing public health issue of diabetes and its complications. The incidence of diabetes is so | Health and Human Services, Department of / National Institutes of Health | 8/20/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $644,602 | Grant | Trans-NIH Recovery Act Research Support: The projected need for Indian rhesus macaques for AIDS-related research continues to exceed availability. Given the interest in nonhuman primates for bioterrorism and emerging disease research, this shortage will likely continue for years to come. While s | Health and Human Services, Department of / National Institutes of Health | 8/25/2009 |
| SEIU EDUCATION AND SUPPORT FUND, INC | $265,136 | Grant | Trans-NIH Recovery Act Research Support: To integrate the Project's hazardous materials emergency training from its Parent Grant into existing workforce development training programs for healthcare. This will be accomplished through collaboration with the Healthcare Career Advancement Program ( | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| WASHINGTON UNIVERSITY, THE | $1,911,255 | Grant | Trans-NIH Recovery Act Research Support: A fundamental assumption in viral research is that viral genes confer pathogenicity. Viral genetics is essential to understanding viral disease, but genetic approaches assume that one knows what genes the virus has. If a virus is significantly more comp | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| HOWARD UNIVERSITY, INC. | $1,259,003 | Grant | Trans-NIH Recovery Act Research Support: Partnership between Howard and Johns Hopkins Cancer Center | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY | $200,001 | Grant | Trans-NIH Recovery Act Research Support: We have requested supplemental funding for the multidisciplinary and highly successful Center for Cancer Nanotechnology of Excellence at MIT and Harvard. Our CCNE focuses on 5 innovative Research Projects. Project 1 (Langer, Farokhzad) investigates novel | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $137,542 | Grant | Trans-NIH Recovery Act Research Support: The need to develop acceptable, available Point-of-Care-Tests (POCT) for identifying Sexually Transmitted Diseases (STDs) in at-risk populations is significant. In the United States, 5 of the top 10 reportable diseases are STDs and, per year, there are >1 | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $768,632 | Grant | Trans-NIH Recovery Act Research Support: The Program seeks to improve our systems-level understanding of the key regulatory elements that direct the host response to serious injury. A greater understanding of the innate inflammatory response to serious injury will lead to the development of nove | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF WASHINGTON | $9,306 | Grant | Trans-NIH Recovery Act Research Support: This supplement is designed to encourage promising undergraduates to pursue a career in biomedical research with an emphasis on reproductive biology. The contributions of these undergraduates to the work on this project will also accelerate the pace of t | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $264,144 | Grant | Trans-NIH Recovery Act Research Support: During the past 15 years, The Harvard Reproductive Endocrine Sciences Center has been dedicated to translational research in reproduction in the human. Its multidisciplinary investigative team and Human Genotyping and Phenotyping Core has now focused on t | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF WASHINGTON | $382,099 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of the ITHS Center for Scientific Review (CSR) is to foster the development of innovative translational and clinical research by leveraging multiple existing sources of pilot funding for our membership and creating new funding programs th | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| NORTHWESTERN UNIVERSITY | $299,086 | Grant | Trans-NIH Recovery Act Research Support: The goal of this CTSA supplement is to accelerate the growth and development of the Northwestern University Clinical and Translational Sciences (NUCATS) Institute's Biomedical Intelligence Core, a partnership between the Kellogg School of Management and t | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $394,988 | Grant | Trans-NIH Recovery Act Research Support: There is an acknowledged 'bench to bedside' gap in translating promising basic biomedical research discoveries into breakthrough medical treatments. Given the inherent risk of early-stage programs, newly discovered therapeutic and diagnostic advances are | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| TRUSTEES OF TUFTS COLLEGE INC | $399,965 | Grant | Trans-NIH Recovery Act Research Support: The Tufts CTSI, created in May 2008 (UL1 RR025752, PI: Dr. Harry P. Selker) includes over 40 institutions and organizations throughout Massachusetts and extends regionally to Maine. One of the core components of the Tufts CTSI is the Novel Methods and Pil | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $380,144 | Grant | Trans-NIH Recovery Act Research Support: All four pilot projects funded by the ARRA Supplement for Pilot Projects are progressing well and are being monitored and assisted by the Harvard Catalyst Research Navigators.For Dr. AbzhanovG??s Characterization of Skeletal Cell Differentiation in Cranio | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $997,354 | Grant | Trans-NIH Recovery Act Research Support: Performing research in community settings requires both a network of practices and community partners committed to research and a system to faciliate researchers' access to these resources. The Indiana CTSI has established primary and specialty care pract | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF UTAH, THE | $996,110 | Grant | Trans-NIH Recovery Act Research Support: This amended application, in response to RFA-RM-07-007: 'Institutional Clinical and Translational Science Award', requests support for the University of Utah's Center for Clinical and Translational Science (CCTS). Our CCTS will build upon the University's | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $597,109 | Grant | Trans-NIH Recovery Act Research Support: Purpose and Expected Outcomes: The goal of this research is to adapt the methods used in the national trial Diabetes Prevention Program, DPP, to the specific needs of high-risk, low-income Latino women with a history of gestational diabetes. We will use | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $588,815 | Grant | Trans-NIH Recovery Act Research Support: One of medicine's greatest challenges today is the efficient, seamless translation of biomedical research discoveries into clinical applications. New methodologies, technologies and integrated information systems offer unprecedented promise for discovery | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $299,790 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement proposal is to further develop online services to support clinical and translational science collaboration needs among researchers and in support of technology transfer to the health care industry. It is also to develop esse | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $50,000 | Grant | Trans-NIH Recovery Act Research Support: This research project will help accelerate the pace of scientific discovery for a patient-oriented clinical research program on novel diagnostics for HIV-associated tuberculosis (TB). | Health and Human Services, Department of / National Institutes of Health | 6/01/2010 |
| TUFTS MEDICAL CENTER PARENT, INC. | $54,000 | Grant | Trans-NIH Recovery Act Research Support: Colorectal cancer is the third leading cause of cancer-related mortality in the USA. This proposal will lay the foundation for the identification of biomarkers which may be used for early detection of colorectal cancer through the analysis of perhaps a s | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| HARVARD PILGRIM HEALTH CARE INC | $978,927 | Grant | Trans-NIH Recovery Act Research Support: The award 'Data Mining Electronic Health Records for Drug Adverse Events' will address the challenge of using informatics for post-marketing surveillance. When a new pharmaceutical drug enters the market, there are always questions about its effectiveness | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| CRESS LLC | $93,640 | Grant | Trans-NIH Recovery Act Research Support: Research into the properties of children's speech production | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $54,000 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the Administrative Supplement application for the parent grant 5K24 DK059492-08 is to create a position at Cincinnati Children's Hospital to meet the needs of the projects supported by the K24 parent grant. The supplement will increase the | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $49,770 | Grant | Trans-NIH Recovery Act Research Support: The project examines the relationship between gastroesophageal reflux and erosive tooth injury. 80 subjects are presently enrolled and will be organized into a databse for analysis, as well as brought in for follow-up. | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| HARVARD PILGRIM HEALTH CARE INC | $90,000 | Grant | Trans-NIH Recovery Act Research Support: ?Pre- and peri-natal predictors of childhood obesity-administrative supplement? Major questions exist regarding pre- and peri-natal influences on childhood growth and adiposity. In previous analyses from Project Viva, we have shown that, consistent wit | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| RESEARCH FOUNDATION FOR MENTAL HYGIENE INC | $2,431,811 | Grant | Trans-NIH Recovery Act Research Support: To support research and other projects that will support fundamental biomedical discovery and translation of that knowledge into effective prevention strategies and new treatments while also providing economic stimulus to the nation. | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $999,974 | Contract | : Millions of patients will be treated for cancer this year. Physicians require a mechanism through which the efficacy of chemotherapeutic treatment can be monitored. While measuring tumor size is important, size may change more slowly than tumor functional | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $754,737 | Contract | : (ARRA) Early therapeutics development with a phase II emphasis. The objectives of these contracts are to conduct Phase 2 and early clinical trials of NCI-sponsored agents to evaluate biologic effects of these agents on their molecular targets, to evaluat | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| NEW YEAR TECH, INC. | $59,453 | Contract | : Additional administrative support to increase compliance oversight activities resulting from the influx of ARRA grants involving laboratory animals. | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UVP, LLC | $11,316 | Contract | : Laboratory equipment | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| SCIENCE APPLICATIONS INTERNATIONAL CORPORATION | $600,000 | Contract | : Web sites and database systems to support the efficient collection, evaluation, review, and reporting of ARRA grant applications for the National Center of Research Resources. | Health and Human Services, Department of / National Institutes of Health | 5/23/2009 |
| CENMED ENTERPRISES INC. | $65,000 | Contract | : 7900HT Fast Real Time 384 Well | Health and Human Services, Department of / National Institutes of Health | 6/29/2009 |
| SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH | $2,227,911 | Contract | : To conduct Phase II and early clinical trials of NCI-sponsored agents, to evaluate biological effects of these agents on their molecular targets, to evaluate other relevant biological effect, and to determine clinically relevant outcomes/correlates. Majo | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $826,635 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Low copy repeats (LCRs; also known as segmental duplications) constitute roughly 5% of the human genome and are known to mediate chromosome rearrangements associated with mental retardation disorders. The long-term goa | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| UNIVERSITY OF MISSOURI SYSTEM | $163,277 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement is requesting salary for the hiring and training of 2 new graduate students dedicated to the proposed studies in the R01 grant 'Aging, Sex, and Neural Cardiovascular Control during Dynamic Exercise' (HL093167-01; PI: Paul J. | Health and Human Services, Department of / National Institutes of Health | 8/07/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $918,643 | Grant | Trans-NIH Recovery Act Research Support: Our project seeks to explore ethical and social challenges in the translation of genetic knowledge to clinical practice in cardiogenetics by 1) reviewing the literature to identify key issues; 2) convening an expert advisory committee to offer expert opin | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| HARVARD PILGRIM HEALTH CARE INC | $1,378,780 | Grant | Trans-NIH Recovery Act Research Support: Obesity has grown unchecked in recent years and has thus far eluded easy answers despite its powerful adverse effects on health. New solutions may very well come from research in health services, health policy, and comparative effectiveness. By funding | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF MISSOURI SYSTEM | $1,222,750 | Grant | Trans-NIH Recovery Act Research Support: According to the American Heart Association, 1 in 3 American adults has cardiovascular disease (CVD) (over 80 million adults) and the WHO indicates that CVD is the number 1 cause of death worldwide. Thus despite major advances in treatment of CVD, it rem | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| HEALTH RESEARCH, INC. | $128,534 | Grant | Trans-NIH Recovery Act Research Support: This application proposes a 5 year translational research training program for the development of an academic career in urologic oncology. The applicant completed urology residency at the University of Chicago and fellowships in urologic oncology and mini | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $1,095,600 | Grant | Trans-NIH Recovery Act Research Support: A long-term goal of our research is to elucidate molecular mechanisms that control axon guidance in the developing vertebrate central nervous system (CNS). In vertebrates, opposed gradients of dorsal midlinederived chemorepellents and VM-associated chemoa | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $456,500 | Grant | Trans-NIH Recovery Act Research Support: This award funds a project directed at developing a therapeutic strategy relevant to lysosomal storage diseases that affect 1 in 8000 children. About half of these disorders, like Tay Sachs disease, also affect the brain, frequently result in early death | Health and Human Services, Department of / National Institutes of Health | 7/19/2009 |
| UNIVERSITY OF DELAWARE | $933,900 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplement project is to greatly expand the parent project by testing the hypotheses that frontal plane kinetic changes that are strongly related to disease progression are present after TKA and these asymmetries can be reduced through | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| UNIVERSITY OF DELAWARE | $395,946 | Grant | Trans-NIH Recovery Act Research Support: O-Xylosyltransferase Shedding in Early Detection of Post-Traumatic Osteoarthritis The objective of the current pilot study is to use a surgical mouse model of acute joint injury to induce knee instability and simulate events leading to post-traumatic OA | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $861,672 | Grant | Trans-NIH Recovery Act Research Support: In this Supplement we will increase the tempo of our research by hiring new personnel and purchasing new equipment. Project 1 will accelerate the tempo of analyzing new molecules in epithelial wound healing by hiring a new postdoctoral fellow. his supple | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $833,162 | Grant | Trans-NIH Recovery Act Research Support: As planned (and described in the recent progress report for our parent grant), we batched specimens from our first three cohorts for our initial set of cell aging work. The Core Immunology Lab is nearly done with phenotyping, sorting and staining PBMC fro | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $90,706 | Grant | Trans-NIH Recovery Act Research Support: The ARRA Administrative Supplement (K08EY018858) supports a parent project that studies The Role of Extracellular Enzymes in Regulating Corneal Repair. The purpose of the project is to investigate the roles of the extracellular enzymes MMP-12 and MMP-8 in | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF DELAWARE | $598,614 | Grant | Trans-NIH Recovery Act Research Support: The goals of this community-based participatory research (CBPR) study are to:-? 1) Expand outreach to older adults affected by cancer and their family caregivers in Delaware. This will include using community stakeholders to guide the researchers in expa | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $986,388 | Grant | Trans-NIH Recovery Act Research Support: Name of Project: Restraint-based modeling of macro- and supramolecular structure: tools and resources for launching calculations, monitoring progress, and viewing and disseminating results. Goals of project: Enhance the capabilities of the UCSF Chimera | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $739,498 | Grant | Trans-NIH Recovery Act Research Support: This is a basic research project seeking to study the role of clusters of genes (called mce operons) of a bacterium that causes tuberculosis (M. tuberculosis) that are important for this organism to maintain latent infection. In particular, these genes a | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF CENTRAL FLORIDA | $38,624 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of my research program is to understand the molecular mechanisms that allow certain AB-type toxins to cross the endoplasmic reticulum (ER) membrane and enter the cytosol of an intoxicated eukaryotic cell. AB toxins consist of a catalyti | Health and Human Services, Department of / National Institutes of Health | 6/03/2009 |
| RESEARCH FOUNDATION FOR MENTAL HYGIENE INC | $397,159 | Grant | Trans-NIH Recovery Act Research Support: This is a supplement to the longitudinal study Transitioning From Childhood to Adulthood: The Impact of Perinatal HIV, informally known as CASAH, to conduct secondary data analysis that will enhance risk prediction. This project will link the data set fr | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $453,156 | Grant | Trans-NIH Recovery Act Research Support: Low copy repeats (LCRs; also known as segmental duplications) constitute roughly 5% of the human genome and are known to mediate chromosome rearrangements associated with mental retardation disorders. The long-term goal of our program is to assess the ro | Health and Human Services, Department of / National Institutes of Health | 4/28/2009 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $945,026 | Grant | Trans-NIH Recovery Act Research Support: Declining immune function is well described in the elderly, and contributes significantly to increased risk and severity of infection, impaired responses to vaccination, and poorer control of cancer. Infections with several pathogens, whether viral (e.g., | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $98,890 | Grant | Trans-NIH Recovery Act Research Support: This is an administrative supplement to R01AI072429 for the purchase of a Guava EasyCyte Plus cytometer. The instrument will be used as an automated cell counter and flow cytometer to enhance and accelerate work associated with R01AI072429, which focuses | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $714,954 | Grant | Trans-NIH Recovery Act Research Support: Dramatic increases worldwide in the incidence of non-Hodgkin lymphoma (NHL) have stimulated considerable efforts to identify factors that may aid in the prevention and treatment of this disease and to further our understanding of the biological mechanisms | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $15,000 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this investigation is to determine the type and frequency of the allelic variants in nuclear modifier gene TRMU involved in phenotypic expression of deafness-associated 12S rRNA mutations in the Chinese populations. For this purpose, we wi | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $99,999 | Grant | Trans-NIH Recovery Act Research Support: Human pluriopotent/embryonic stem cells (HESCs) are a promising renewable source of material for transplantation. However genetically incompatible HESC-based approaches would require the use of aggressive immunosuppressive therapy following transplantatio | Health and Human Services, Department of / National Institutes of Health | 8/12/2009 |