Listing all stimulus spending by amount, in descending order. Return to National Institutes of Health page
Amount refers to both the amount of stimulus funding going toward the project and the face value of the loan.
| Recipient | Amount | Type | Description | Federal Dept./Agency | Date |
|---|---|---|---|---|---|
| NORTHWESTERN UNIVERSITY | $51,256 | Grant | Trans-NIH Recovery Act Research Support: 12 and IL-18 are key mediators promoting inflammatory reactions. Localized inflammatory responses are important mechanisms to limit pathogen infections and to promote wound healing. However, excessive and uncontrolled production of IL-12 and IL-18 and res | Health and Human Services, Department of / National Institutes of Health | 7/30/2009 |
| MARQUETTE UNIVERSITY | $32,093 | Grant | Trans-NIH Recovery Act Research Support: This grant created a summer research experience for 2 college students in health-related scientifice research. Despite intense research efforts, drug addiction persists as a serious public health problem for which no effective treatment exists. Although | Health and Human Services, Department of / National Institutes of Health | 6/25/2009 |
| UNIVERSITY OF TEXAS M.D. ANDERSON CANCER CENTER, THE | $139,734 | Grant | Trans-NIH Recovery Act Research Support: One of the major challenges of modern medicine is the development of novel approaches for the efficient delivery of therapeutics and molecular specific treatment of pathology that can be carried out under imaging guidance and monitoring. Recent advances i | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $54,050 | Grant | Trans-NIH Recovery Act Research Support: Although many therapeutic strategies exist for molecular targets accessible from the outside of the cell (e.g. therapeutic antibodies) or within the cytoplasm (e.g. small molecule inhibitors), they are not applicable to molecular targets that lie within t | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| OREGON STATE UNIVERSITY | $105,407 | Grant | Trans-NIH Recovery Act Research Support: Hmong women in the U.S. get screened for breast and cervical cancer (BCC) at remarkably low rates. Cultural and social factors, including those reflecting the Hmong's unique history and experience, are thought to affect BCC screening behavior among Hmong | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF WASHINGTON | $18,769 | Grant | Trans-NIH Recovery Act Research Support: This is an Administrative Supplement Request to NIDA for two SummerResearch Opportunities for High School and Undergraduate Students(NOT-OD-09-060). Our goal is to support Mr. Jeffrey S. Smith, aundergraduate neurobiology major in his 3rd year at the Uni | Health and Human Services, Department of / National Institutes of Health | 6/19/2009 |
| UNIVERSITY OF NORTH CAROLINA AT GREENSBORO | $59,288 | Grant | Trans-NIH Recovery Act Research Support: Oral Health Disparities among Elders with and without Cognitive Impairments aims to assess the relationship of cognitive impairment with declining oral health among older adults. There is strong clinical evidence to suggest an increased incidence of ora | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $99,999 | Grant | Trans-NIH Recovery Act Research Support: The primary goal of the parental proposal is to develop novel dental nanocomposite materials using hydroxyapatite nanocrystals and elastin-based biopolymers containing motifs identified by natural and artificial evolutionary processes. Elastin is a biopol | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF WASHINGTON | $307,349 | Grant | Trans-NIH Recovery Act Research Support: This is a competitive revision application in response to Notice Number NOT-OD-09-058, title: Enabling RPGs to Leverage NCRR Center and Center-like Programs. Chronic orofacial pain is a relatively common, poorly understood set of conditions that lacks def | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $242,055 | Grant | Trans-NIH Recovery Act Research Support: This is a Competitive Revision application associated with my active NIH grant entitled Defining target contribution to orofacial pain by antisense oligonucleotides (1R21DE019298-01) in responding to Notice Number (NOT-OD-09-058) and Notice title: NIH An | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $63,700 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Parathyroid hormone (PTH) is well known for its catabolic and anabolic actions in bone. PTH is now in clinical use for its ability to restore bone lost to osteoporosis, and also under investigation for its use in the r | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY | $89,148 | Grant | Trans-NIH Recovery Act Research Support: Our long-term objective for this proposed research is to discover novel treatments for red cell disorders with hemoglobinopathy. In this supplement proposal, we will accelerate and extend the research proposed in the parent grant for the screening small c | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $9,270 | Grant | Trans-NIH Recovery Act Research Support: We hypothesize that strengthening muscles may be an alternative for improving gait and function in children with cerebral palsy. Our long-term objective is to develop an improved strengthening therapy compared to today's approaches. Our proposed therapy i | Health and Human Services, Department of / National Institutes of Health | 5/28/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $93,665 | Grant | Trans-NIH Recovery Act Research Support: Our goal in the parent grant is to develop fast methods to predict and validate ultrasound dose in regions of interest during mild hyperthermia, including predictions of the 3D geometry, the temperature profile, the specific absorption and the cumulative | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $31,545 | Grant | Trans-NIH Recovery Act Research Support: We propose to develop a photonic-based sensing layer for the spatial and temporal determination of proteins within the microenvironment of a wound. This program will combine Protein Imprinted Xerogels with Integrated Emission Sites (PIXIES) with photonic | Health and Human Services, Department of / National Institutes of Health | 6/16/2009 |
| CHILDREN'S RESEARCH INSTITUTE | $64,851 | Grant | Trans-NIH Recovery Act Research Support: The overall purpose of this Administrative Supplement Recovery Act award is (i) to enhance and accelerate the tempo of our research towards the successful completion of the R21 EY016723-01A2 funded project dealing with proteomics study of age related macu | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| UNIVERSITY OF MONTANA SYSTEM | $50,827 | Grant | Trans-NIH Recovery Act Research Support: The proposed project is to provide useful information on the central mechanisms of mRNA/tRNA movement on the ribisome, the translocation step. To determine how the ribosome, a two-part macromolecular complex, maintains register with the mRNA/tRNA complex | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $32,651 | Grant | Trans-NIH Recovery Act Research Support: The major goals of this project are to generate genetic models of iron deficiency in a selected area of the brain, the hippocampus which mediates recognition memory behavior. Two mouse strains are being generated. The first employs Cre Lox P technology to | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| CHARLOTTE-MECKLENBURG HOSPITAL AUTHORITY, THE | $51,307 | Grant | Trans-NIH Recovery Act Research Support: Voting Empowerment Study among People with Traumatic Brain Injury The project describes the experiences around the process of voting, from the point of view of adults with Traumatic Brain Injury (TBI) and any feelings of disenfranchisement that may occur | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| REHABILITATION INSTITUTE OF CHICAGO | $6,644 | Grant | Trans-NIH Recovery Act Research Support: This award is issued in response to Notice OD-09-060, Recovery Act Administrative Supplements Providing Summer Research Experiences for Students and Science Educators. The goal of this project is to design and develop a hand exoskeleton to facilitate reha | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| NORTH CAROLINA STATE UNIVERSITY | $48,759 | Grant | Trans-NIH Recovery Act Research Support: The proposed research aims at laying the fundaments for developing a sequencing device that can be deployed at point-of-care locations. In this capacity it will help guide therapies in which the genetic makeup of a patient is important to the suitability | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $282,299 | Grant | Trans-NIH Recovery Act Research Support: The rupture of unstable atherosclerotic plaque is the most frequent event leading to thrombus mediated ischemic cardiovascular disease, which remains the leading cause of mortality in industrialized societies. The processes leading to plaque vulnerability | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $204,225 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The annual incidence of myocardial infarction is nearly one million and yet no therapy currently exists to restore lost muscle function following an attack. Stem cell recruitment and/or transplantation are potential s | Health and Human Services, Department of / National Institutes of Health | 8/12/2009 |
| ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE | $101,463 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this Exploratory/Developmental Research Grant is to discover the effects of endocannabinoids (eCB) in rostral ventrolateral medulla (RVLM) circuits that regulate cardiovascular function. The central nervous system is directly involved | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON | $7,223 | Grant | Trans-NIH Recovery Act Research Support: Vascular diseases can cause premature deaths. These deaths can be prevented by knowing who is at risk for the disease. The studies proposed are to identify the genes that predispose individuals to a number of vascular diseases. PUBLIC HEALTH RELEVANCE: Th | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| UNIVERSITY OF WASHINGTON | $93,312 | Grant | Trans-NIH Recovery Act Research Support: The Department of Environmental and Occupational Health Sciences in the University of Washington School of Public Health and Community Medicine proposes to supplement its summer research training experience for undergraduate science students under the NIE | Health and Human Services, Department of / National Institutes of Health | 6/17/2009 |
| RFCUNY - LAGUARDIA COMMUNITY COLLEGE | $269,621 | Grant | Trans-NIH Recovery Act Research Support: Education Projects: For support to develop and/or implement a program as it relates to a category in one or more of the areas of education, information, training, technical assistance, coordination, or evaluation. | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY ENTERPRISES, INC. | $55,636 | Grant | Trans-NIH Recovery Act Research Support: This project used administrative supplement funds made available by the American Recovery and Reinvestment Act of 2009 (ARRA) to stimulate the economy through the procurement of additional supplies and equipment needed to accelerate the pace of scientific | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| RFCUNY - HUNTER COLLEGE | $277,845 | Grant | Trans-NIH Recovery Act Research Support: This non-competitive supplemental application seeks to hire a full-time, PhD level, Professional Developmental Coordinator and a part-time Computer Specialist. The Coordinator would be the instructor for Science 200.03 G?? Introduction to Biomedical Rese | Health and Human Services, Department of / National Institutes of Health | 7/31/2009 |
| UNIVERSITY OF ARIZONA | $95,869 | Grant | Trans-NIH Recovery Act Research Support: Our current IMSD grant provides first year stipend and tuition to URMs in one of 14 biomedical Ph. D. programs, a one semester graduate survival seminar, and $1500 to attend a national conference in their field, as well as financial support to 8 undergrad | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| FOUNDATION FOR BLOOD RESEARCH | $146,726 | Grant | Trans-NIH Recovery Act Research Support: The proposed supplemental project will extend the educational impact and dissemination of BiomedicineWorks beyond the parent grant target population to include low-income, first-generation, underrepresented students participating nationally in Upward Bo | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| OREGON MUSEUM OF SCIENCE AND INDUSTRY | $155,765 | Grant | Trans-NIH Recovery Act Research Support: The Oregon Museum of Science and Industry (OMSI) received an administrative supplement to extend the reach of our parent project Small Museum Research Collaborative (SMRC): Exhibit-Based Outreach (5R25RR22741-04) to additional venues. OMSI will create a h | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $178,039 | Grant | Trans-NIH Recovery Act Research Support: Use of nonhuman primates requires specialized training and experience on part of veterinary and animal husbandry staff. Opportunities for individuals to acquire such skills are few and currently there is a shortage of qualified veterinarians to fill this | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| THE VANDERBILT UNIVERSITY | $97,840 | Grant | Trans-NIH Recovery Act Research Support: The current supplement proposal will build on the parent grant G?School for Science and Math at VanderbiltG? Specific Aim #2: The School for Science and Math at Vanderbilt (SSMV) will develop and implement an interdisciplinary, sequential, four-year curri | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| TRUSTEES OF TUFTS COLLEGE INC | $107,958 | Grant | Trans-NIH Recovery Act Research Support: This Fogarty ARRA Supplement for Support of a Framework program in Global Health has two specific aims: 1. The development of an academic course in Implementation Science to complement prior courses developed with Framework assistance at Tufts. This cour | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE | $106,908 | Grant | Trans-NIH Recovery Act Research Support: Via this supplement, we will increase incorporation of Information and Communication Technologies (ICT) in our Framework activities to reinforce our global health educational network, with an emphasis on implementation sciences. Specific activities will i | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $335,604 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Improvements in the treatment of brain tumors have produced little impact on outcomes over the past three decades. Still, survival for both pediatric and adult brain tumors is known to be maximized by radiographically | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF ROCHESTER | $309,807 | Grant | Trans-NIH Recovery Act Research Support: This award is an administrative supplement to enhance the comparative effectiveness research activities for the oR34 study entitled Forensic Assertive Community Treatment: An Emerging Model of Care.-? This administrative supplement award will accelerate s | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF WASHINGTON | $131,211 | Grant | Trans-NIH Recovery Act Research Support: The primary goal of this supplement is to expedite data analysis and manuscript development relevant to the major aims of the parent grant. The overall goal of the parent grant (R37 AG024102) is to examine whether cognitive status and cognitive change in | Health and Human Services, Department of / National Institutes of Health | 6/30/2009 |
| BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | $710,968 | Grant | Trans-NIH Recovery Act Research Support: potent inhibition of HIV-1 infection in cultured cells. We will extend our analyses of these constructs to primary CD34+ cells and T-lymphocytes as part of specific aim 1. In aim 2 further analyses of the functional role of HIV-1 RNA trafficking through t | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $46,597 | Grant | Trans-NIH Recovery Act Research Support: The search for novel anti-AIDS therapeutic agents has principally focused on the development of drugs that interfere with specific stages of the HIV life cycle. This targeted pharmacological approach has resulted in therapeutic agents that are extremely e | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $11,787 | Grant | Trans-NIH Recovery Act Research Support: Glycogen is a branched storage polymer of glucose that serves as an energy reserve in many cell types. In absolute terms, liver and skeletal muscle house the largest glycogen deposits in mammals and are critical to whole body glucose metabolism. The overa | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF ARIZONA | $605,250 | Grant | Trans-NIH Recovery Act Research Support: This is an application for a competitive supplement for grant 5R37DK33209-27, in response to NIH Notice Number (NOT-OD-09-058) entitled G?NIH Announces the Availability of Recovery Act Funds for Competitive Revision ApplicationsG?. The original applicatio | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| CASE WESTERN RESERVE UNIVERSITY | $59,540 | Grant | Trans-NIH Recovery Act Research Support: There is increasing evidence that cytokines, in general, and tumor necrosis factor (TNF), in particular, may play a key role in the pathogenesis of Crohn's disease (CD), one of the known idiopathic inflammatory bowel diseases (IBD)s. The most compelling e | Health and Human Services, Department of / National Institutes of Health | 9/10/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The kidney regulates water/salt balance, nitrogenous waste, blood pressure and blood composition. Kidney function is vital to homeostasis of the body fluids. Chronic kidney disease affects one in nine Americans, a similar number are at risk. The heath car | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| MICHIGAN STATE UNIVERSITY | $85,000 | Grant | Trans-NIH Recovery Act Research Support: The overall objective of this proposal is to further our understanding of how energy conversion is accomplished in cytochrome c oxidase (CcO) and how rate and efficiency is controlled. In this grant period we propose to continue our analysis of the struct | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| OMEROS CORPORATION | $334,600 | Grant | Trans-NIH Recovery Act Research Support: The funds provided by this Revision grant are being used to accelerate the development of a novel clinical candidate for the treatment of osteoarthritis (OA), a disease that currently affects 22% of the US population but has no effective treatment. We wi | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| SEACOAST SCIENCE, INC. | $11,376 | Grant | Trans-NIH Recovery Act Research Support: Summer Intern support for NIEHS program developing w-cost chemical sensors for detecting and monitoring environmental clean-up, remediation, and decommissioning processes where groundwater may be contaminated. | Health and Human Services, Department of / National Institutes of Health | 7/10/2009 |
| VIOCARE, INC. | $182,575 | Grant | Trans-NIH Recovery Act Research Support: Title: Diet Assessment System for Cancer Control Applications This administrative supplement proposal to our parent grant, ?Diet Assessment System for Cancer Control Applications?, addresses the accelerated development and commercialization of the Graphi | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| INTELLIGENT OPTICAL SYSTEMS, INC. | $199,961 | Grant | Trans-NIH Recovery Act Research Support: Intelligent Optical Systems (IOS) proposes to accelerate the commercialization of a simple to use, point of care clinical assay system that can be used for the early screening of ovarian and other cancers as well as for a wide range of other diagnostic te | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| AMBION DIAGNOSTICS, INC | $199,766 | Grant | Trans-NIH Recovery Act Research Support: This project is an Administrative Supplement for Workforce Enhancement of an existing phase II SBIR. In research completed for the parent grant, we developed techniques for microarray-based analysis of RNA from formalin?fixed, paraffin embedded ??FFPE?? t | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| MORPHORMICS INC | $309,717 | Grant | Trans-NIH Recovery Act Research Support: System for Automatic Segmentation of Male Pelvis Structures from CT Images - The purpose of this supplement is to accelerate commercialization of technology to automatically segment anatomical structures in the male pelvis from 3D medical images such as C | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| MAGNESENSORS, INC. | $390,199 | Grant | Trans-NIH Recovery Act Research Support: Nanotechnology based magnetic detection for rare cell assays. This supplement is requested to add a highly experienced scientist to significantly enhance and accelerate our existing Phase II SBIR by bringing the fabrication of the magnetic nanoparticle r | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| SENEX BIOTECHNOLOGY | $200,000 | Grant | Trans-NIH Recovery Act Research Support: Title: Inhibitors of disease-promoting activities of senescence This project is aimed at developing a new class of drugs, which inhibit pathogenic activities of senescent cells. Cell senescence occurring as a result of aging or cellular damage is associat | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| OSMIC ENTERPRISES, INC. | $219,225 | Grant | Trans-NIH Recovery Act Research Support: The parent grant (Cellulose-Based Strips for Human Taste Function) involves the development of edible taste strips that contain either sweet, sour, salty, or bitter taste stimuli for use in a clinical taste test. Currently, no commercially available taste | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| EXPERIMED BIOSCIENCE, INC. | $480,491 | Grant | Trans-NIH Recovery Act Research Support: Overall purpose: discovery of drugs for a large class of targets recalcitrant to current drug discovery approaches. Initial deliverable: drug for Bcl, a well known cancer target poorly served by current drug discovery approaches. | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| UNIVERSITY OF MIAMI | $382,500 | Grant | Trans-NIH Recovery Act Research Support: We have been fortunate to receive support from an ARRA supplement to perform novel work dealing with toll-like receptors and their role in intestinal epithelial cell biology and cancer. In the last several months, we have successfully characterized the ex | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| NEW YORK MEDICAL COLLEGE | $394,800 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this award to perform research on streptococci and streptococcal diseases in order to better understand the underlying molecular processes, eventually leading to better design of preventative and therapeutic strategies. Group A streptococc | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| INSTITUTE FOR HEPATITIS & VIRUS RESEARCH, THE | $305,542 | Grant | Trans-NIH Recovery Act Research Support: Chronic hepatitis B is the major cause of primary liver cancer worldwide, and also often results in liver cirrhosis and, more rarely, acute liver failure. In the establishment of chronic infection, the salient feature of the hepatitis B virus (HBV) life | Health and Human Services, Department of / National Institutes of Health | 6/03/2009 |
| VIRGINIA COMMONWEALTH UNIVERSITY | $366,523 | Grant | Trans-NIH Recovery Act Research Support: Lyme disease, the leading arthropod borne disease in N. America and Europe, is caused by the spirochetes Borrelia burgdorferi, B. garinii and B. afzelii. As the endemic regions and incidence of Lyme disease increase, there is a pressing need to advance ou | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $404,880 | Grant | Trans-NIH Recovery Act Research Support: Malaria parasites, worldwide are responsible for 300-500 million new infections and 1-2 million deaths each year. An effective vaccine, however, remains elusive, partly due to antigenic diversity and the immune evasion strategies of the parasite. Recombin | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $300,000 | Grant | Trans-NIH Recovery Act Research Support: Chemokines regulate the traffick and function of various immune effector cells and play a critical role in host defense against a variety of intracellular pathogens. The CXC chemokine receptor 3 (CXCR3) is expressed on plasmacytoid dendritic cells, neutro | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| NEW YORK BLOOD CENTER, INC., THE | $315,570 | Grant | Trans-NIH Recovery Act Research Support: The overall purpose of the funded project is to study the association between P. falciparum ligand polymorphisms and the RBC invasion profiles used by the Amazonian field isolates and/or the ability of the variant ligand to bind to RBCs with defined pheno | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF WASHINGTON | $306,400 | Grant | Trans-NIH Recovery Act Research Support: Mycoplasma genitalium is a newly recognized genital pathogen associated with urethritis in men and endometritis (inflammation of the uterus) and cervicitis (inflammation of the cervix) in women. We have shown that, untreated, M. genitalium persists in the | Health and Human Services, Department of / National Institutes of Health | 7/31/2009 |
| TRUSTEES OF TUFTS COLLEGE INC | $412,500 | Grant | Trans-NIH Recovery Act Research Support: Many gram negative bacterial pathogens, including Yersinia, Salmonella, Pseudomonas, Shigella, enteropathogenic E. coli, Chylamydia, and Burkholderia, use type III secretion systems (TTSS) to translocate effector proteins from the bacterial cytosol into m | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF PUERTO RICO-MEDICAL SCIENCES CAMPUS | $93,747 | Grant | Trans-NIH Recovery Act Research Support: The specific goal of this supplement request is to provide research employment for Mrs. Mar+?a del Rocio Castro. Mrs. Castro is a research specialist in the laboratory of my collaborator Dr. Sylvette Ayala-Torres. The project that sponsors Mrs. Castro ( | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (INC) | $131,397 | Grant | Trans-NIH Recovery Act Research Support: Individual investigator-initiated research projects for faculty at MSIs to conduct research of limited scope in environments with limited research infrastructure/facilities. | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| DUKE UNIVERSITY | $98,742 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Over one million Americans will suffer from cancer every year, and approximately half of them will die from the disease. Despite major efforts to prevent cancer, effective early diagnosis and treatment of non- metastat | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $76,638 | Grant | Trans-NIH Recovery Act Research Support: This is a minority supplement to our parent pediatric cancer epidemiology training grant (T32CA099936). This supplement provides support for a minority student to do research into the causes and consequences of pediatric cancer. | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF OREGON | $41,118 | Grant | Trans-NIH Recovery Act Research Support: The the Systems Training Grant (STG) is a predoctoral training program in systems neuroscience, now in its 34th year. The objective of the program is to produce innovative, intellectually critical, and experimentally skilled scientists equipped for basic | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| TRUSTEES OF TUFTS COLLEGE INC | $97,028 | Grant | Trans-NIH Recovery Act Research Support: The M.D./Ph.D. program at Tufts University School of Medicine and the Sackler School of Graduate Biomedical Sciences is designed to train the physician scientists of the future, and provide an outstanding cadre of investigators well-versed in both the pra | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $91,682 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): We are requesting continued funding of the Medical Sciences Training Program (MSTP) at the University of Wisconsin-Madison. The MSTP has made significant progress in its mission to provide outstanding, integrated trai | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $128,992 | Grant | Trans-NIH Recovery Act Research Support: The goal of this training grant proposal is to prepare gifted predoctoral trainees for productive research careers in the field of signaling and cellular regulation. The training faculty consists of an outstanding, internationally recognized group of inve | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $45,612 | Grant | Trans-NIH Recovery Act Research Support: This proposal requests funding for predoctoral training in the Bioinformatics Program at the University of Michigan. This is a multidisciplinary graduate training program in bioinformatics and computational molecular biology drawing faculty from the Schoo | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| MISSOURI SYSTEM, UNIVERSITY OF | $83,034 | Grant | Trans-NIH Recovery Act Research Support: This biostatistics research training program's goal is to establish and provide an internationally recognized predoctoral, interdisciplinary program that is strong in biostatistical theory and methodology, and also integrates biostatistics training with f | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| THE VANDERBILT UNIVERSITY | $52,283 | Grant | Trans-NIH Recovery Act Research Support: The primary aim of this interdisciplinary training program is to produce leading scientists who will contribute to the state of knowledge about neurobiological and psychosocial mechanisms underlying the development, maintenance, and remission of psychopat | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $51,635 | Grant | Trans-NIH Recovery Act Research Support: The main focus of this project is to further understand the laminar circuitry of the cerebral cortex that underlies the enhanced visual sensory processing due to attentional selection. The neural circuitry that is embedded within layered structure of the | Health and Human Services, Department of / National Institutes of Health | 7/21/2009 |
| UNIVERSITY OF CALIFORNIA, SANTA CRUZ | $41,203 | Grant | Trans-NIH Recovery Act Research Support: The mission of UCSC MARC U*STAR program is to prepare underrepresented minority students for admission to Ph.D. programs and professional research careers in the biomedical sciences concordant with the mission statement of the NIGMS MARC U*STAR program. T | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| CASE WESTERN RESERVE UNIVERSITY | $78,930 | Grant | Trans-NIH Recovery Act Research Support: This award is an adminstrative supplement for a T32 training grant that supports the Genetics Graduate Training Program at Case Western Reserve University (Case). The goal of the Genetics Training program at Case is to train pre-doctoral students in the u | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $42,869 | Grant | Trans-NIH Recovery Act Research Support: MUSC has been measuruing ethanol concentrations in relatively small tissue samples using a gas chromoatograph (GC). The GC we are currently using is over 25 years old and we have been informed by the company (Schmadzu) that it can no longer be reparied ( | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| UNIVERSITY OF PITTSBURGH THE | $38,164 | Grant | Trans-NIH Recovery Act Research Support: This award provides funds to enable us to purchase equipment that is critical to our alcohol research program. The backbone of our alcohol research program is the production of genetically engineered (knockin and knockout) mice. Funds to purchase (A) a | Health and Human Services, Department of / National Institutes of Health | 8/12/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $310,220 | Grant | Trans-NIH Recovery Act Research Support: The long-range goal of our therapeutic development endeavors is to develop efficacious and safe agents to prevent and/or delay progression of age-related neurodegenerative disease such as Alzheimer's. Toward that end, we propose a preclinical project to d | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $246,792 | Grant | Trans-NIH Recovery Act Research Support: The goal of our U01 parent grant is to bring a first-in-class novel chemical entity, functioning as a potent and specific small molecule ligand for the p75 neurotrophin receptor, through milestones allowing IND approval for phase 1 trials in Alzheimer's d | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $492,599 | Grant | Trans-NIH Recovery Act Research Support: The Multicenter AIDS Cohort Study (MACS), a comprehensive cohort study ongoing since 1984, has contributed to the understanding of the natural history of HIV infection and the impact of highly active antiretroviral therapies (HAART). Combining genetic, vi | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| PHARMACEUTICAL PRODUCT DEVELOPMENT, INC. | $750,000 | Grant | Trans-NIH Recovery Act Research Support: Complete mechanistic assay analysis and provide additional support for the completion of the final study manuscript for two studies that have been complete (SWO1 and CN01). The funding will allow in depth analysis of assay data that have been collected a | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $367,249 | Grant | Trans-NIH Recovery Act Research Support: Statistical and Data Management Center - Pediatric, Adolescent and Maternal Clinical Trials Group (CTG) - Administrative Supplement to provide a PROMISE (Promoting Maternal & Infant Survival Everywhere) Training Coordinator to develop, oversee and coordin | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $7,312,062 | Grant | Trans-NIH Recovery Act Research Support: North American AIDS Cohorts Collaboration on Research and Design A disturbing increase in the incidence of non-AIDS-defining conditions including renal disease, metabolic and cardiovascular disease, and malignancies has been observed in recent years, and | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE | $528,932 | Grant | Trans-NIH Recovery Act Research Support: Chronic allograft nephropathy (CAN) remains the most common cause of graft loss. However, the term CAN does not delineate the specific underlying pathologic process but rather refers to the chronic injury resulting from multiple potential factors. More re | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF PITTSBURGH THE | $68,540 | Grant | Trans-NIH Recovery Act Research Support: Specific Aim to the supplement: To determine pathological and innate immune responses to various isolates of H1N1 variant viral challenges. We will establish the baseline innate immune response and pathology in ferrets to H1N1 influenza infection using | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | $332,000 | Grant | Trans-NIH Recovery Act Research Support: The principal goal of this application by a group of molecular and clinical pharmacologists, molecular biologists, and clinical scientists from the California Cancer Consortium (CCC) comprised of three NCI-designated Cancer Centers is to develop new labor | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| FOX CHASE CANCER CENTER | $442,077 | Grant | Trans-NIH Recovery Act Research Support: Abstract: The Philadelphia Breast Cancer Family Registry is a clinic-based site, one of six collaborating Breast Cancer Family Registry (B-CFR) sites sponsored by the NCI. The overall goal is to maintain, enhance and exploit the research potential of the | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | $245,571 | Grant | Trans-NIH Recovery Act Research Support: The proposed administrative supplement is to provide support for two part-time bilingual patient navigators (Vietnamese and Chinese) and pilot test our Hepatitis B patient navigation intervention program. The pilot patient navigation intervention primaril | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| WAYNE STATE UNIVERSITY (INC) | $199,883 | Grant | Trans-NIH Recovery Act Research Support: The primary objective of this study is to accelerate the temp of scientific research in the Detroit area focused on reducing racial health disparities of older, underserved African American (AA) cancer survivors. We propose using a Community Based Partici | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF KENTUCKY | $251,985 | Grant | Trans-NIH Recovery Act Research Support: A multidisciplinary team of collaborators from academic institutions and communities in Appalachian regions of Kentucky, West Virginia, Ohio, Pennsylvania, New York, Maryland and Virginia are proposing to build on a strong foundation of previous activity | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO | $294,538 | Grant | Trans-NIH Recovery Act Research Support: This is a regional/programmatic network/center dedicated to cancer health disparities research and care through a Geographic Management Program (GMap). GMap, a program of NCI's CRCHD (National Cancer Institute's Center to Reduce Cancer Health Disparities) | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| FORSYTH DENTAL INFIRMARY FOR CHILDREN | $187,189 | Grant | Trans-NIH Recovery Act Research Support: The long-term objective of this research is to characterize the cultivable and currently uncultivated microorganisms present in the human oral cavity (microbiome) and all of their genes (metagenome) in order to develop an integrated view of host-microbiom | Health and Human Services, Department of / National Institutes of Health | 5/01/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $100,402 | Grant | Trans-NIH Recovery Act Research Support: The Administrative Supplement to Look AHEAD will increase the scientific impact of Look AHEAD and retain and/or create new staff positions. Look AHEAD is a randomized, controlled, multi-center clinical trial comparing the long-term health effects of an in | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $143,136 | Grant | Trans-NIH Recovery Act Research Support: The CRIC study participants are a diverse group of people with kidney disease, half of whom have diabetes. The CRIC study goals are to identify clinical factors such as blood or urine tests, or evidence of disease in other organs (heart, brain) that cont | Health and Human Services, Department of / National Institutes of Health | 9/02/2009 |
| EMORY UNIVERSITY | $110,085 | Grant | Trans-NIH Recovery Act Research Support: Title of the award is Administrative Supplements for HALT Polycystic Kidney Disease Clinical Trial Network. The specific aims of the work to be supported by the requested administrative supplement will accelerate and expand the work plan contemplated unde | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF PITTSBURGH THE | $150,000 | Grant | Trans-NIH Recovery Act Research Support: Pediatric Acute Liver Failure (PALF) results from excessive or maladaptive inflammation. Coupling broad clinical, inflammation biomarker (Luminex (TM)), and physiologic assessments with sophisticated mathematical modeling techniques will fundamentally alt | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| THE VANDERBILT UNIVERSITY | $5,239,099 | Grant | Trans-NIH Recovery Act Research Support: The mission of the Beta Cell Biology Consortium (BCBC) is to bring a team-based approach to the acquisition of new knowledge and the production of novel resources necessary to develop cell-based therapies for insulin delivery. The main research strategies | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERISTY OF MISSISSIPPI MEDICAL CENTER | $149,746 | Grant | Trans-NIH Recovery Act Research Support: Supplemental administrative funding will be used to hire an additional clinical research nurse to ensure that the current protocols of the NIH Gastroparesis Clinical Research Consortium (GpCRC) are continued and that proposed studies can be started this y | Health and Human Services, Department of / National Institutes of Health | 8/27/2009 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $366,736 | Grant | Trans-NIH Recovery Act Research Support: It is estimated that up to 50,000 children are newly diagnosed annually in the United States with vesicoureteral reflux (VUR) after a urinary tract infection. It is known that in some of these children, VUR is associated with recurrent infection, pyelonep | Health and Human Services, Department of / National Institutes of Health | 8/21/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $124,467 | Grant | Trans-NIH Recovery Act Research Support: Valid murine models of diabetic nephropathy (DN) should replicate the molecular changes and not simply the pathological alterations of patients with DN. Thus, our general hypothesis for development and testing of murine models of diabetic nephropathy is t | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $1,600,000 | Grant | Trans-NIH Recovery Act Research Support: With the help of Dr. Kidd, we have been able to deal effectively with the large data sets coming from the immune monitoring of the vaccine studies, relating serum cytokine results with phosphoflow assays, cell phenotyping and gene expression data, without | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $437,021 | Grant | Trans-NIH Recovery Act Research Support: The central element in allergic diseases such as asthma, rhinitis and eczema, is the presence of IgE antibody. While there is general acceptance of the central role for IgE in these diseases, there remains only a poor understanding of the quantitative req | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO | $407,890 | Grant | Trans-NIH Recovery Act Research Support: Mycoplasma pneumoniae is a human pathogen that preferentially infects the respiratory tract. Recent data suggest that M. pneumoniae is responsible for 20-40% of all community acquired pneumonia and is frequently linked to acute and chronic respiratory inf | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| UNIVERSITY OF TEXAS M D ANDERSON | $579,499 | Grant | Trans-NIH Recovery Act Research Support: The proposed studies will test the overall hypothesis that TSLP is a master switch for developing and maintaining atopy and asthma. TSLP is a hematopoietic cytokine encoded on the human chromosome 5q22 cluster of Th2 cytokine genes, and in humans is produ | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| WISTAR INSTITUTE OF ANATOMY & BIOLOGY (INC) | $161,177 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this application is to define the factors that shape antiviral T and B cell immunity and delineate the mechanisms by which these factors operate. We have focused on three factors that could shape effector and memory lymphocyte differen | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $61,650 | Grant | Trans-NIH Recovery Act Research Support: The innate immune system is a cooperative network of host defenses that utilizes both soluble components and cellular defenses. Central to innate immune recognition are pattern recognition receptors (PRRs) that recognize pathogen derivatives or altered-se | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| FRONTIER SCIENCE & TECHNOLOGY RESEARCH FOUNDATION, INC. | $97,644 | Grant | Trans-NIH Recovery Act Research Support: The ECOG Pathology Coordinating Office-Reference Laboratory (PCO-RL) continues to serve as a centralized facility that supports scientific endeavors within ECOG and between cooperative groups. The ECOG PCO-RL has embedded uniform SOPs into CTEP approved c | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $300,000 | Grant | Trans-NIH Recovery Act Research Support: Cancer Genome Characterization Using Gene Expression and DNA Copy Number Analysis Cancer is a disease of dysregulated gene/protein function, and therefore, a systematic determination of the genes that are altered in expression and/or sequence will identi | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $523,967 | Grant | Trans-NIH Recovery Act Research Support: Cancer Genome Characterization Center at Johns Hopkins: In the past two decades, it has become clear that cancer arises not only as a consequence of genetic events, such as mutations, copy number alterations, and sequence rearrangements, but also as a res | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $23,942 | Grant | Trans-NIH Recovery Act Research Support: This application for an administrative supplement will provide internships for Americans (a High School student and two teachers) to experience diverse research investigations relating to non-invasive assessment of tumor development, progress, and respons | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| MASSACHUSETTS EYE AND EAR INFIRMARY & PHYSICIAN STAFF, INC. | $309,566 | Grant | Trans-NIH Recovery Act Research Support: Otopathology of Light Microscopy and Molecular Techniques Furthers the mission of the Consortium by incorporating new imaging technology and data management techniques, as well as by promoting innovative collaborative research that utilizes modern bio | Health and Human Services, Department of / National Institutes of Health | 6/30/2009 |
| UNIVERSITY OF PUERTO RICO-MEDICAL SCIENCES CAMPUS | $732,089 | Grant | Trans-NIH Recovery Act Research Support: The objective of this proposal is to establish at the Caribbean Primate Research Center (CPRC) a new specific pathogen free SPF colony of Indian origin rhesus macaques to help meet National demand for these animals. The founding stock of this colony will | Health and Human Services, Department of / National Institutes of Health | 9/05/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $815,936 | Grant | Trans-NIH Recovery Act Research Support: The goal of this proposal is to use a new technique for molecular typing of major histocompatibility complex type I molecules to provide detailed genetic information on the entire specific pathogen free rhesus macaque colony at the New England Primate Res | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF IOWA, THE | $400,000 | Grant | Trans-NIH Recovery Act Research Support: An essential element of the RFA entitled Institutional Clinical and Translational Science Award, CTSA, is the creation of an academic home that is a department, center, or institute. In response to the RFA, the University of Iowa will create The Universit | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $300,000 | Grant | Trans-NIH Recovery Act Research Support: The goal of this supplement is to perform biomarker developmental research to establish predictive markers of thyroid and head and neck cancer and/or prognosis/response to therapy. | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| TRUSTEES OF TUFTS COLLEGE INC | $577,811 | Grant | Trans-NIH Recovery Act Research Support: The Tufts Clinical and Translational Science Institute (CTSI)'s Community Engagement (CE) component is committed to fostering creative, reciprocal interactions between communities and researchers necessary for transformative clinical and translational res | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $650,000 | Grant | Trans-NIH Recovery Act Research Support: The Carolina Center of Cancer Nanotechnology Excellence (C-CCNE) arose from a convergence of research in the physical, biological and translational sciences, nurtured at the University of North Carolina and organized by the university?s NCI-designated Lin | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| WASHINGTON UNIVERSITY, THE | $912,000 | Grant | Trans-NIH Recovery Act Research Support: The parent grant entitled Photoacoustic/optical/ultrasonic imaging of sentinel lymph nodes and metastases covers the development of photoacoustic tomography (PAT) and multimodality imaging of SLN and metastases. PAT is one of the fastest growing biomedica | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $257,589 | Grant | Trans-NIH Recovery Act Research Support: This is an application for a 1-year, administrative supplement to 5U54EB005149 (National Alliance for Medical Image Computing), in response to NOT-OD-09-056. The goal of this project is to strenghten the components of the open-source NA-MIC kit for suppor | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF PITTSBURGH THE | $235,701 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this award is identical to that stated in the original application: it is to preserve key positions in the Administrative Core, Primate Core, and Project II of the Specialized Centers Program in Reproduction and Infertility Research at the | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF WASHINGTON | $242,347 | Grant | Trans-NIH Recovery Act Research Support: The University of Washington U54 SCCPIR center is entitled Clinical and Basic Studies in Male Reproduction and this request for an administrative supplement is responsive to the intent of ARRA to promote job creation and accelerate the pace and achievemen | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $50,000 | Grant | Trans-NIH Recovery Act Research Support: The Ligand Core has used the Immulite 1000 automated immunoassay analyzer to measure reproductive hormones in human clinical research samples over the past 8 years. The increase in assays needed for samples associated with new A/B projects over the next y | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF ILLINOIS | $7,399 | Grant | Trans-NIH Recovery Act Research Support: PROJECT FOR MS. EMILY IONETZ SPECIFIC AIM G?? Does the surgical removal of endometriotic lesions during the early (1 month) or transition (6 month) phases of the induced disease result in the reestablishment of a receptive endometrium? Experimental A | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $222,548 | Grant | Trans-NIH Recovery Act Research Support: The events necessary for ovulation and, thus, fertilization include the development of an ovulatory follicle possessing a mature egg, follicle rupture, as well as the detachment of the oocyte and surrounding cumulus cells from the wall of the follicle. F | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| DUKE UNIVERSITY | $329,997 | Grant | Trans-NIH Recovery Act Research Support: NOT-OD-09-056 NIH Announces the Availability of Recovery Act Funds for Administrative Supplements: Creating the Encyclopedia of DNA Elements (ENCODE) in the Human Genome U54 The primary focus of our ENCODE group is to generate an open chromatin atlas tha | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| CHARLES DREW UNIVERSITY OF MEDICINE AND SCIENCE | $999,702 | Grant | Trans-NIH Recovery Act Research Support: On behalf of the 18 Research Centers in Minority Institutions (RCMI), Charles R. Drew University submits this application to design and implement the RCMI Translational Research Network (RTRN or Network). The successful translation of research findings to | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| MOREHOUSE SCHOOL OF MEDICINE, INC., THE | $894,640 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of the Morehouse School of Medicine (MSM) RCMI Center of Excellence in Clinical and Translational Research (R-CENTER) is to train the next generation of minority clinical and translational scientists to pursue multidisciplinary approach | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| MEHARRY MEDICAL COLLEGE | $391,120 | Grant | Trans-NIH Recovery Act Research Support: The Meharry Medical College Clinical and Translational Research Center (MeTRC) grant will be used to fund meritorious pilot projects in clinical and basic science research. | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| DUKE UNIVERSITY | $400,000 | Grant | Trans-NIH Recovery Act Research Support: DTRI uses an innovative, focused, and proactive approach with its pilot projects that has increased our success in translation. The supplemental funding will be used to fund two projects (1) 'PTEN Gene Therapy for the Prevention of Vein Graft Disease' and | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $1,009,381 | Grant | Trans-NIH Recovery Act Research Support: Supplemental funds are requested to study systematically potential differences in the response to COX-2 selective vs non-selective NSAIDs in an approach that integrates (i) quantitative signatures of drug response in cellular and in vivo model systems ? e | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| MAYO CLINIC | $523,069 | Grant | Trans-NIH Recovery Act Research Support: Over the last decade NIH has reported a decrease in the number of physician-scientists applying for research and training awards. 'Increasing advances in the basic sciences that have progressed to clinical relevance have not been matched by an adequate gr | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $596,314 | Grant | Trans-NIH Recovery Act Research Support: Our goals for this supplement are to 1) engage in a public awareness campaign about the Community Connect to Research resource, 2) gather feedback on its design, content, and usefulness, 3) expand and enhance it with additional content, and 4) ultimately, | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $863,573 | Grant | Trans-NIH Recovery Act Research Support: One of medicine's greatest challenges today is the efficient, seamless translation of biomedical research discoveries into clinical applications. New methodologies, technologies and integrated information systems offer unprecedented promise for discovery | Health and Human Services, Department of / National Institutes of Health | 9/26/2009 |
| VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | $232,400 | Grant | Trans-NIH Recovery Act Research Support: The overall goals of this International Cooperative Biodiversity group are to achieve the threefold mission of biodiversity conservation, economic development, and drug discovery in Madagascar. The proposed research integrates the work of seven different | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| RESEARCH FOUNDATION FOR MENTAL HYGIENE INC | $830,926 | Grant | Trans-NIH Recovery Act Research Support: The on-going study investigates how social-environmental exposures and selected biologicals, including the relationship between cortisol levels and resting heart rate, relate to a wide range of psychological outcomes. This supplement seeks to extend thes | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $153,500 | Grant | Trans-NIH Recovery Act Research Support: Fossil fuel burning power plants emit high levels of airborne pollutants associated with respiratory infections, chronic respiratory illness and aggravation of existing cardiovascular disease. Power plants also emit low levels of uranium, thorium, and oth | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| MISSOURI SYSTEM, UNIVERSITY OF | $18,538 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Enzymes in the a-D-phosphohexomutase superfamily play critical roles in carbohydrate metabolism and other biosynthetic pathways. The biological importance of these proteins is demonstrated by their distribution in natu | Health and Human Services, Department of / National Institutes of Health | 6/03/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $364,227 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Patient navigation (PN) is a widely used intervention approach in initiatives to reduce cancer health disparities and facilitate access to care, particularly in African American (AA) populations. However, the results o | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $105,566 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The long-term objective of this project is to understand the factors that have broad roles in transcriptional regulation in eukaryotes, utilizing the powerful combination of genetic and biochemical techniques available | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $637,850 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Our goal is to elucidate the physical and molecular basis of homeostasis and misfolded protein stress in the endoplasmic reticulum (ER). Correct folding and quality control of secretory proteins by ER chaperones is ess | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $66,815 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): All enveloped viruses enter cells by a membrane fusion reaction and produce progeny virus by budding through a cellular membrane. Semliki Forest virus (SFV) is a well-characterized alphavirus that infects cells by low | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| RIPPLE EFFECT CMMNICATIONS INC | $326,485 | Contract | : This contract was awarded to acquire additional staffing for professional support services for OD/OER - Task 13 - Communications and Project Management Support using ARRA funds under existing, competitively-awarded, small businessset-aside task order no. | Health and Human Services, Department of / National Institutes of Health | 8/08/2009 |
| MISSOURI SYSTEM, UNIVERSITY OF | $207,013 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Pre-B-cell colony enhancing factor (PBEF) is a unique, little-studied cytokine, whose relevance to the lung pathophysiology is unknown. Recent work by the PI has provided the first evidence of PBEF expression in lung | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| HARVARD PILGRIM HEALTH CARE INC | $26,594 | Grant | Trans-NIH Recovery Act Research Support: The parent grant (R01 HD050966(Gillman, PI)) aims to assess whether a comprehensive, innovative, primary care practice change intervention can prevent obesity among children age 2-6 years at elevated risk of obesity. The primary aims of the parent grant | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| EMMES CORPORATION, THE | $303,260 | Contract | : The goal of the ActNow Project Manager is to lead to enhanced accrual and more expeditious completion of high-priority cancer clinical trials. The ACTNOW Project Manager will track the progress of 37 cancer clinical trials over the course of two years, i | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| SAIC FREDERICK, INC | $8,868,207 | Contract | : The back office infrastructure project was established to provide support functions for the ARRA projects in areas such as Finance, Accounting, Audit, IT, Subcontracts, Human Resources, Project Management, and administrative support, to include materials/ | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| PROSOURCE CONSULTING, L.L.C. | $1,180,000 | Contract | : ProSource Consulting, LLC has been contracted to provide safety engineering, safety support, and owner advocacy services for the American Reinvestment and Recovery Act (ARRA) funded projects. ProSource provides owner advocacy services for DOHS for constru | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| CONTEMPORARIES, INC. | $53,664 | Contract | : PERFORM ARRA GRANTS MANAGEMENT IN DERA'S OFFICE OF GRANTS MANAGEMENT. | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| GENERAL ELECTRIC COMPANY | $102,300 | Contract | : GE TRACERlab, this is an automated system for the production of general 18FYF Fluoride Based Tracers, used for Nuclear / PET diagnostic medical imaging. The award is for the delivery and installation of the system. Unit of measure 1. | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| COMPUTERBILITIES, INC | $18,040 | Contract | : Recovery-DERT ARRA Desktops and Laptops | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| CASPIAN SEA LLC | $108,000 | Contract | : Professional and Scientific Support for Grant Review Services Resulting from American Recovery and Reinvestment Act (ARRA) of 2009 | Health and Human Services, Department of / National Institutes of Health | 6/22/2009 |
| CENMED ENTERPRISES INC. | $52,418 | Contract | : LC-401 Revolution for NIH/NIAA | Health and Human Services, Department of / National Institutes of Health | 9/02/2009 |
| SCIENCE APPLICATIONS INTERNATIONAL CORPORATION | $193,200 | Contract | : Provide software development and support services to the NIH Office of Extramural Research (OER) for the Electronic Research Administration (eRA) systems and databases with respect to two the project to build a systems interface between the NIH eRA system | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| RANGER GROUP LLC, THE | $4,089,805 | Contract | : Recovery Act -- Repair & Upgrade Switchgear -- Building 41 | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| CHUGACH WORLD SERVICES, INC. | $99,895 | Contract | : Replacement of the tube nest and condensate reciever associated with a heat exchanger. | Health and Human Services, Department of / National Institutes of Health | 9/19/2009 |
| NORTHERN TAIGA VENTURES, INC. | $596,142 | Contract | : Building 10, Cell Processing Unit - Correct Deficiencies. | Health and Human Services, Department of / National Institutes of Health | 4/29/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $830,000 | Grant | Trans-NIH Recovery Act Research Support: The variety of forms and the complex pathogenesis of cardiac arrhythmias suggest the contribution of numerous molecular mechanisms to the cardiac rhythm whose individual and combined alterations may generate heart failure. Deficient expression and mutatio | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $829,985 | Grant | Trans-NIH Recovery Act Research Support: The primary features of sickle cell disease are events resulting in low flow, poor perfusion and blood and tissue hypoxia that are both pre-disposing to and the consequence of vaso-occlusion. We will test the overall hypothesis that BH4 (tetra-hydrobiopte | Health and Human Services, Department of / National Institutes of Health | 8/21/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $108,000 | Grant | Trans-NIH Recovery Act Research Support: ABSTRACT Our hypothesis is that various signaling molecules send information to the nucleus in a tonic fashion to maintain the phenotype of certain developmental stages of thymocytes as well as the stable phenotype of the peripheral T lymphocyte. The bigg | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF FLORIDA | $104,716 | Grant | Trans-NIH Recovery Act Research Support: Pain is one of the most costly and pervasive public health problems threatening the United States. While ethnic disparities in pain and its treatment have been reported, the influence of ethnicity on responses to analgesics has received scant attention. | Health and Human Services, Department of / National Institutes of Health | 8/15/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $995,960 | Grant | Trans-NIH Recovery Act Research Support: Title: Estimating the Environmental Burden in Two Orphan Lung Diseases The population attributable fraction (PAF) estimates the amount of a disease that is due to a specific factor, quantifying the burden of disease that would be prevented if that factor | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF DELAWARE | $887,766 | Grant | Trans-NIH Recovery Act Research Support: Shape Up! Preschoolers' Geometric Sense Predicts Future Mathematics Achievement The purpose of this longitudinal research is to develop an assessment of 36- to 38-month-old children's knowledge of fundamental geometric spatial and shape concepts in order | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF ILLINOIS | $516,590 | Grant | Trans-NIH Recovery Act Research Support: The proposed project seeks to develop a technology platform for providing high-sensitivity detection of biomolecules and substantial amplification of fluorescence output on large-area, plastic based nanostructured surfaces called G?photonic crystals (PC). | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $54,000 | Grant | Trans-NIH Recovery Act Research Support: This is the final report for this award. The project is complete, but the research effort did not exhaust the funds awarded. Closeout documents have been submitted to the NIH NINDS for processing and the remainder of the award is being returned to the NIH | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $51,925 | Grant | Trans-NIH Recovery Act Research Support: This award provides funds to accelerate the tempo of my scientific research on the role of the microglia/macrophage response in brain tumor progression and invasion; it allows me to hire a full-time technician and procure needed resources and equipment. | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $54,000 | Grant | Trans-NIH Recovery Act Research Support: Grant Name: Obesity and Urinary Incontinence (OUI) To explore a novel treatment for urinary incontinence, mindfulness-based weight loss, and investigate possible mechanisms of the treatment effect of weight loss on urinary incontinence a randomized cli | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $1,253,713 | Grant | Trans-NIH Recovery Act Research Support: 'The goal of this proposal is to elucidate serotonin signaling pathways through genetic dissection of genes and functional pathways regulated by Selective Serotonin Reuptake Inhibitors (SSRIs). Dysregulation of serotonin neurotransmission is a reproduci | Health and Human Services, Department of / National Institutes of Health | 5/07/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $249,251 | Grant | Trans-NIH Recovery Act Research Support: San Francisco Mammography Registry-A Research Source -- We examined the influence of dense volume and texture features by type of breast cancer [ductal carcinoma in situ (DCIS) vs. invasive cancer]. Using 168 invasive breast cancers and 504 controls and 6 | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $450,000 | Grant | Trans-NIH Recovery Act Research Support: Allergic disorders are a major public health problem affecting 50 million people in the United States alone. Epithelial cells are the first cells that encounter environmental exposures and they are responsible for intitiating the response to environmenta | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF ILLINOIS | $39,067 | Grant | Trans-NIH Recovery Act Research Support: Colon cancer is one of the most frequently diagnosed cancers in the United States. Poor prognosis also makes it one of the deadliest cancers. Dietary factors are closely associated with tumorigenesis and development of colon cancer. Soy foods and soy bioa | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| MAYO CLINIC | $499,997 | Contract | : Supplemental funding to an exisitng contract is being provided under the CTEP Accelerating Clinical Trials of Novel Oncologic PathWays (ACTNOW) program for a protocol entitled 'Phase II trial of CDK inhibitor SCH727965 in multiple myeloma'. Multiple myel | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF MASSACHUSETTS | $577,657 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this proposal is to determine the role of N-linked glycans in the maturation and quality control of proteins that traverse the secretory pathway. The majority of proteins that travel through the secretory pathway receive multiple N-lin | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| RESEARCH FOUNDATION FOR MENTAL HYGIENE INC | $395,000 | Grant | Trans-NIH Recovery Act Research Support: To support research and other projects that will support fundamental biomedical discovery and translation of that knowledge into effective prevention strategies and new treatments while also providing economic stimulus to the nation. | Health and Human Services, Department of / National Institutes of Health | 5/15/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $403,146 | Grant | Trans-NIH Recovery Act Research Support: There is considerable clinical interest in using synthetic ligands of Toll-like receptor 9 (TLR9) to treat infectious disease, generate better vaccines, and alleviate symptoms of allergy or asthma. Unfortunately, differences in the function of TLR9 in hum | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE | $423,500 | Grant | Trans-NIH Recovery Act Research Support: The major goal of this proposal is to understand the molecular mechanism(s) of liver fibrosis by hepatitis C virus (HCV) infection. Hepatitis C virus (HCV) is the leading cause of chronic liver disease worldwide. HCV infection often leads to chronic hepat | Health and Human Services, Department of / National Institutes of Health | 5/15/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $999,903 | Grant | Trans-NIH Recovery Act Research Support: The grant name is UCSF Living Heart Resource. Establish the infrastructure to obtain, in a standardized manner, diseased and healthy human cardiac tissue obtained at surgery for immediate electromechanical studies to further the fundamental understanding | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF TOLEDO, THE | $799,426 | Grant | Trans-NIH Recovery Act Research Support: This is a proposal to validate the accuracy of a multi-gene Lung Cancer Risk Test (LCRT). An accurate LCRT may be used to design more efficient lung cancer screening and/or chemoprevention studies by enabling enrollment of the highest risk individuals, re | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $378,278 | Grant | Trans-NIH Recovery Act Research Support: Title: 'Effect of Obesity on Long-Term Clinical Outcomes after Kidney Donation' - Examine the effects of obesity on long-term renal function and development of cardiavascular risk factors such as hypertension, dyslipidemia, and metabolic syndrome in patie | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF ILLINOIS | $290,675 | Grant | Trans-NIH Recovery Act Research Support: Chronic bacterial lung infections are the major cause of death in cystic fibrosis. In such chronic infections, antibiotic-resistant bacterial biofilms are formed in the lungs of cystic fibrosis patients. Biofilms are poorly understood due in part to the i | Health and Human Services, Department of / National Institutes of Health | 5/30/2009 |
| UNIVERSITY OF DELAWARE | $476,442 | Grant | Trans-NIH Recovery Act Research Support: Center of Biomedical Research Excellence for Women in Science and Engineering on Osteoarthritis. Our purpose is to train women in science and engineering to do biomedical research. Our research is on osteoarthritis. | Health and Human Services, Department of / National Institutes of Health | 7/10/2009 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $994,437 | Grant | Trans-NIH Recovery Act Research Support: As part of the P30 Asthma Research Core, we will use the monies to support additional new faculty in Asthma Research through a Pilot grant program. We will award two grants of $50,000 each year for two years. Recipients of a pilot grant in year 1 can ap | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $954,923 | Grant | Trans-NIH Recovery Act Research Support: P30 RFA is to support the hiring of newly recruited faculty to develop research projects within the context of MQIR Core Center. We enhance this core with two key faculty recruitments. 1) A faculty position focused on developing imaging techniques, utiliz | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $219,317 | Grant | Trans-NIH Recovery Act Research Support: The proposed line of research is directly related to our funded studies of DEK gene function entitled G?Role and regulation of the human DEK oncogene.G? DEK expression is upregulated in a wide variety of human cancers, and DEK had therefore long been susp | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $15,000 | Grant | Trans-NIH Recovery Act Research Support: In response to NOT-OD-09-060 Administrative Supplements Providing Summer Research Experiences for Students and Science Educators under the Recovery Act, this study proposes a 3-month summer project for two undergraduate students, one from statistics and o | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $29,639 | Grant | Trans-NIH Recovery Act Research Support: To our knowledge, no research group has conducted and analyzed direct observation of family interactions that focus on promotion of adolescent autonomy in the management of Type 1 diabetes and the relationship to treatment adherence in a prospective study | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $233,084 | Grant | Trans-NIH Recovery Act Research Support: Supplemental Aim 1. We will elucidate the role of TopBP1 in linking Rad9 to ATR-dependent regulation of FANCD2 monoubiquitination in hematopoietic cells. G?? We will examine the requirement for TopBP1 in regulating FANCD2 monoubiquitination in CD34+ cell | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $687,893 | Grant | Trans-NIH Recovery Act Research Support: Aim 1: Define mechanisms by which TLR2 activation modulates endothelial cell (EC) expression of coagulation pathway factors in vitro. We defined the role of MAP kinases and NF-kB in EC TLR2 signaling to inflammatory mediators and PAI-1. Notable findings w | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $577,058 | Grant | Trans-NIH Recovery Act Research Support: Project Title: Role of s-nitroso-glutathione reductase in hepatocellular carcinoma. The overall goal of this proposal is to determine if S-nitroso-glutathione reductase is critically important for protection against liver tumorigenesis. We expect that th | Health and Human Services, Department of / National Institutes of Health | 5/08/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $797,214 | Grant | Trans-NIH Recovery Act Research Support: The name of this grant is Impact of Core Implementation Components on Adoption. This grant supports a study of translational research investigating how effective drug abuse treatments move from multi-site effectiveness research into application in the tre | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF DELAWARE | $97,465 | Grant | Trans-NIH Recovery Act Research Support: Research Equipment for Advancement of Science: An Administrative Supplement for R01 DC008965 The purpose of the grant is to enhance the productivity through the purchase of essential instrument. | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $109,574 | Grant | Trans-NIH Recovery Act Research Support: The goal is to understand the underpinnings of hormone action as it relates to extracellular fluid volume and electrolyte regulation. This will provide insight into the pathogenesis of hypertension, congestive heart failure and electrolyte disorders. | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $230,464 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this project is to develop methods to address the complexity of modern PKPD population studies focusing on computational PKPD and modeling of comples PKPD systems. Aim1: to investigate modern algorithms and approximations to the likelihood | Health and Human Services, Department of / National Institutes of Health | 9/08/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $828,922 | Grant | Trans-NIH Recovery Act Research Support: This supplement funded studies centered on a poorly understood fundamental aspect of P450 regualation and turnover, focusing on two P450s that significantly contributed to clincally relevant drug metabolism. | Health and Human Services, Department of / National Institutes of Health | 6/11/2009 |
| UNIVERSITY OF DELAWARE | $473,350 | Grant | Trans-NIH Recovery Act Research Support: PRO: A Protein Ontology in Open Biomedical Ontologies - Administrative Supplement for PRO complex ontology Biomedical ontologies are increasingly important in systems biology research where complex data need to be integrated and scientific knowledge nee | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF MARYLAND | $112,807 | Grant | Trans-NIH Recovery Act Research Support: The traditional view of protein evolution has been that all protein domains are descendents of distinct evolutionary lines, that there are a relatively small number of such lines (about 1000), and that these lines are all of relatively ancient origin. Two | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| CARNEGIE MELLON UNIVERSITY | $346,796 | Grant | Trans-NIH Recovery Act Research Support: These funds are being used to develop a new approach to single molecule detection with improved brightness and flexibility. The studies are designed to establish the feasibility of this labeling strategy in single molecule analysis in living cells. This | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $1,406,387 | Grant | Trans-NIH Recovery Act Research Support: Late Parenting & Biotechnology: Rethinking Age, Gender, Family, & the Life Course. Late parenthood is a recent phenomenon which reflects both a shift in the reproductive pattern of the baby boom generation and the development and proliferation of advance | Health and Human Services, Department of / National Institutes of Health | 8/24/2009 |
| ILLINOIS INSTITUTE OF TECHNOLOGY | $229,517 | Grant | Trans-NIH Recovery Act Research Support: Research Associate, to be named. A research associate will greatly enhance execution and needed technical evaluation to achieve project goals with additional rigor, and give more clinical relevance to project outcomes. In the next two years it is crucia | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $774,862 | Grant | Trans-NIH Recovery Act Research Support: R01NS055915-01A2. We have quantified the expression of the basal lamina proteins collagen IV and laminin after acute neonatal and adult stroke using a 3D reconstruction system. We also conducted additional Western Blot experiments to quantify the role of | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $289,326 | Grant | Trans-NIH Recovery Act Research Support: This ARRA grant for project titled Preclinical development of a gene therapy for Niemann-Pick disease, type A provides research involving rodent and non-human primate experiments studying lysosomal dysfunction in Niemann-Pick Disorder (NPD) Type A, to det | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| ARIZONA STATE UNIVERSITY | $151,636 | Grant | Trans-NIH Recovery Act Research Support: This request for administrative supplement facilitates effort on our currently funded project, 'The adaptability of cortex in learning modified control algorithms for neuroprosthetics.' Three measures increase the tempo of research without impacting the s | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| NORTHEASTERN UNIVERSITY | $390,000 | Grant | Trans-NIH Recovery Act Research Support: Allosteric Modulators of cbl cannabinoid receptor | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| ARIZONA STATE UNIVERSITY | $404,810 | Grant | Trans-NIH Recovery Act Research Support: This project is an exploratory endeavor to adapt the assimilation frameworks employed to assess generational differences in social and economic well-being among adolescents and adults with the ecological developmental framework developed to understand the | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| ARIZONA STATE UNIVERSITY | $405,027 | Grant | Trans-NIH Recovery Act Research Support: The overarching goal of this project is to develop and test a dynamic model of the co-evolution of peer networks, health behavior, and psychological well-being, which can be used to better target health interventions. Researchers have long investigated th | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $424,875 | Grant | Trans-NIH Recovery Act Research Support: Cell-based therapies for the repair and tissue regeneration of heart tissue, for example following heart infarct, may provide great promise, and human embryonic stem cells are being considered as a cell source for these cells, called cardiomyocytes. We n | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $386,250 | Grant | Trans-NIH Recovery Act Research Support: This project studies a protein that is important for regulation of human glucose metabolish because it controls how muscles remove glucose from the bloodstream in response to insulin. Notably the protein of interest called CHC22 clathrin is present in hu | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF ILLINOIS | $420,937 | Grant | Trans-NIH Recovery Act Research Support: The following application will focus on determining the mechanism by which the influenza A protein, NS1, blocks nuclear RNA-export function. This Inhibition of cellular mRNA export is an integral component of the influenza A offensive repertoire against i | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $994,917 | Grant | Trans-NIH Recovery Act Research Support: In 2005, nearly 40% of the US population had diabetes or pre-diabetes. Diabetes is caused by insufficient insulin production by the pancreatic beta cell. In this grant, we propose to identify novel genes that are important for insulin production. We hope | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| VAXART, INC | $1,246,796 | Grant | Trans-NIH Recovery Act Research Support: 'Vaxart is developing a new vaccine to prevent infection by Venezuelan Equine Encephalitis (VEE), a pathogen that can infect laboratory workers and has biowarfare potential. Because of the dangers involved with previous vaccines, we propose to develop a s | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| STEELWORKERS CHARITABLE & EDUCATIONAL ORGANIZATION | $720,250 | Grant | Trans-NIH Recovery Act Research Support: The Steelworkers Charitable and Educational Organization's (SCEO) Tony Mazzocchi Center (TMC), which is a joint project of the United Steelworkers (USW) and the Labor Institute, received $720,250 in supplemental training funds from the National Institute | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| NATIONAL DEVELOPMENT AND RESEARCH INSTITUTES, INC. | $984,649 | Grant | Trans-NIH Recovery Act Research Support: The computerized intervention we will evaluate in this project, if found effective and cost-effective, could substantially advance the adolescent substance abuse treatment system by markedly improving the availability and quality of HIV (and infectious di | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | $999,833 | Grant | Trans-NIH Recovery Act Research Support: Multimodality Optical Imaging Tools for Cocaine Studies' will address the broad Challenge Area (06: Enabling Technologies) and Specific Challenge topic (06-DA-102: Tool Development for the Neurosciences). The central goal of this proposal is to develop no | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF OREGON | $946,906 | Grant | Trans-NIH Recovery Act Research Support: The goal of this research is to improve the implementation effectiveness and dissemination of the Family Check-Up (FCU), an ecologically based child and family intervention designed to reduce substance use, support positive family interactions, and reduce | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| AMERICAN LEGACY FOUNDATION | $977,346 | Grant | Trans-NIH Recovery Act Research Support: Many national consensus documents emphasize the enormous potential to maximize the reach, use, and population impact of smoking cessation interventions via tobacco quitlines. The population impact of quitlines remains small (reach x effcacy / cost), beca | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| NORTHWESTERN UNIVERSITY | $952,729 | Grant | Trans-NIH Recovery Act Research Support: Mammals including humans need amplification by outer hair cells (OHCs) for their high sensitivity and sharp frequency selectivity. OHCs are also the most vulnerable cells in the inner ear and are involved in a majority of sensorineural hearing loss. Altho | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $843,333 | Grant | Trans-NIH Recovery Act Research Support: The primary goal of this application is to establish and validate a robust, safe and long-lasting delivery method using somatic stem cells as vectors to transport biologically active molecules into the inner ear. Somatic stem cells, such as mesenchymal st | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $678,768 | Grant | Trans-NIH Recovery Act Research Support: The critical features that predict the transition from acute to chronic pain remain unresolved. The present proposal explores whether microglial 'priming' may be of particular importance in explaining the progression from acute to chronic pain. Activation | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| SEATTLE CHILDREN'S HOSPITAL | $954,646 | Grant | Trans-NIH Recovery Act Research Support: Planning Grant for Genome-Wide Association by Study of Craniofacial Microsomia -- CFM involves the asymmetric underdevelopment of facial skeletal bones and soft tissue and occurs in over 1 in 3500 births. Typically affecting the jaw and ear, CFM impairs | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $978,862 | Grant | Trans-NIH Recovery Act Research Support: Needle biopsy is a regularly performed procedure required for diagnosing prostate cancer (PC). An estimated 1.3 million biopsies are performed yearly in the US at a healthcare cost of $2.6 billion. Biopsies are typically triggered by elevated prostate spe | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| WGBH EDUCATIONAL FOUNDATION | $996,208 | Grant | Trans-NIH Recovery Act Research Support: Teachers Domain: Environmental Health. The WGBH Educational Foundation will produce, assemble, and disseminate a multimedia collection of purpose-built resources to assist K-12 teachers and students to engage deeply with issues of environmental health. D | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| TOWSON UNIVERSITY | $35,519 | Grant | Trans-NIH Recovery Act Research Support: The overall purpose of this grant is focused on understanding the recognition, coding, and analysis of taste stimuli by receptor cells housed within gustatory sense organs (sensilla) using an insect model, namely gypsy moth caterpillars (Lymantria dispar) | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| THE VANDERBILT UNIVERSITY | $269,630 | Grant | Trans-NIH Recovery Act Research Support: p120-catenin (p120) and ?-catenin are armadillo repeat proteins that directly bind and regulate E-cadherin, a major cell-cell adhesion receptor with tumor- and metastasis-suppressor activity. ?-catenin is also an important component of the Wnt signaling p | Health and Human Services, Department of / National Institutes of Health | 9/02/2009 |
| LOUISIANA STATE UNIVERSITY SYSTEM | $270,382 | Grant | Trans-NIH Recovery Act Research Support: Successful eradication of solid tumors and metastatic disease by immunotherapy requires systemic and persistent functional anti-tumor cytotoxic T lymphocytes (CTL). Dendritic cells (DC), as the pivotal initiator and regulator of immune responses, have bec | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| HENRY FORD HEALTH SYSTEM | $146,474 | Grant | Trans-NIH Recovery Act Research Support: Prior efforts have illustrated the time constraints faced by primary care physicians when delivering preventive health services. Limited time and competing demands force physicians and patients to make choices about what topics to address in any given of | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $317,729 | Grant | Trans-NIH Recovery Act Research Support: We have generated a robust new model of colitis-associated colorectal cancer that provides insight into both disease pathogenesis and novel therapeutic approaches and also furnishes ample opportunities for future basic science discovery and pre-clinical t | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $377,129 | Grant | Trans-NIH Recovery Act Research Support: Fresh fruits and vegetables are indisputable parts of a healthy diet. These foods contain a number of chemical compounds that have been shown to protect against tumor development in animal models of carcinogenesis. Unfortunately, a mechanistic understan | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF LOUISVILLE | $262,578 | Grant | Trans-NIH Recovery Act Research Support: This project funding represents a supplement related to faculty/coordinator salaries that continued ongoing Pediatric Clinical Pharmacology Research (PPRU) clinical studies including data analysis/publication for applicable studies. No additional subject | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| CHILDREN'S RESEARCH INSTITUTE | $298,830 | Grant | Trans-NIH Recovery Act Research Support: Dr. John N. van den Anker (P.I. of the PPRU at CNMC) and Mrs. Elaine Williams (the nurse coordinator of the PPRU at CNMC) have diligently worked together since the last ARRA report. In January, February and March 2011 we had still a total of 9 PPRU studie | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $1,529,800 | Grant | Trans-NIH Recovery Act Research Support: Immune Responses to the Novel H1N1 Flu Virus. Human infections caused by a novel influenza A (H1N1) virus (originating in swine) were first diagnosed in the spring of 2009 in North America, and the virus has subsequently spread rapidly to >100 countries, | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| BAYLOR RESEARCH INSTITUTE, THE | $5,292,047 | Grant | Trans-NIH Recovery Act Research Support: Vaccination represents one of the major successes of medicine as it has spared countless people from polio, tetanus and other acute infections. Yet, improved immunization strategies are needed to make vaccines for microbes that cause considerable morbidit | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF ROCHESTER | $301,387 | Grant | Trans-NIH Recovery Act Research Support: Funding of this supplement will, among other things, ensure the development and retention of a junior faculty member with unique expertise in neonatal lung injury who otherwise would have to pursue other research. The central theme of our Center is the c | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $399,999 | Grant | Trans-NIH Recovery Act Research Support: Based on our U19 funding, we have shown that calibration based on ex-vivo irradiations (i.e. taking blood samples from healthy unirradiated volunteers, and irradiating the blood ex-vivo) is a scientifically valid approach (2), and following a pre-IDE meet | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $751,375 | Grant | Trans-NIH Recovery Act Research Support: In this renewal, the overall goals of this Autoimmunity Prevention Center Project are: 1) To determine, in human autoimmune disease, which of the CD4+CD25+ subsets of DR+ and DR regulatory T cells are defective; 2) The identification of a core set of gene | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| WASHINGTON UNIVERSITY, THE | $492,583 | Grant | Trans-NIH Recovery Act Research Support: Influenza viruses are a frequent cause of acute, severe respiratory illness, but the role of these types of viruses in triggering chronic inflammatory lung disease is uncertain. We previously reported that a common type of paramyxovirus (i.e., mouse parai | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $603,162 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of the UW AADCRC is to define mechanisms for rhinovirus (HRV)-induced exacerbations of asthma. Since the beginning of this U19 contract, our center has made considerable progress in each of the 4 funded projects, and the Virology Core h | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| VIRGINIA COMMONWEALTH UNIVERSITY | $579,311 | Grant | Trans-NIH Recovery Act Research Support: The proposed supplement to 'Cellular Inflammatory Pathways in Asthma & Allergic Diseases: From IgE to Cells' will enable the hiring of additional staff, increase the hours of certain part-time staff and procure additional equipment aimed to enhance and ex | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| WAYNE STATE UNIVERSITY (INC) | $32,680 | Grant | Trans-NIH Recovery Act Research Support: My current NIH funding explores the function of frataxin in the yeast and human model systems. My pending UMDF grant utilizes the fly model system to explore the structure and function of proteins (including frataxin) during Fe-S cluster biosynthesis. T | Health and Human Services, Department of / National Institutes of Health | 6/25/2009 |
| YALE UNIVERSITY | $394,000 | Grant | Trans-NIH Recovery Act Research Support: This proposal requests supplemental funds to enhance and accelerate progress on the parent grant, IBD Genetics Consortium Data Coordinating Center (U01 DK62429). The Data Coordinating Center (DCC) is jointly operated between Yale University and the Univer | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $1,025,763 | Grant | Trans-NIH Recovery Act Research Support: The Department of Medical Informatics & Clinical Epidemiology (DMICE) of Oregon Health & Science University (OHSU) is pleased to submit a competitive continuation for its National Library of Medicine (NLM) fellowship training program for a fourth five-yea | Health and Human Services, Department of / National Institutes of Health | 7/23/2009 |
| YALE UNIVERSITY | $1,000,000 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area 06: Enabling technologies and specific Challenge Topic Breakthrough technologies for neuroscience (06-NS-103). The title of this proposal is Genomewide screening of transmembrane accessory subunits of ion ch | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| TRUDEAU INSTITUTE, INC. | $999,999 | Grant | Trans-NIH Recovery Act Research Support: This proposal addresses preventative vaccine development for ?-herpesvirus-associated malignancies. We will determine the efficacy and safety of various genetically engineered ?-herpesviruses as vaccines using a mouse ?-herpesvirus, ?HV68 | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| YALE UNIVERSITY | $9,889,558 | Grant | Trans-NIH Recovery Act Research Support: The main goal of the presently assembled Grand Opportunity consortium is to conduct a spatiotemporally comprehensive survey of the human brain transcriptome and create a unique multimodal atlas encompassing all pre- and postnatal developmental stages, inc | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF ALASKA ANCHORAGE | $1,811,076 | Grant | Trans-NIH Recovery Act Research Support: This award is consistent with the research priorities of RFA-OD-09-004 (RC2), 'Expanding and Personalizing Treatment Options for Alcohol Disorders'. NIAAA's RFP guidelines suggest a particular interest in the development of technological innovations aime | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $1,889,958 | Grant | Trans-NIH Recovery Act Research Support: High Performance Computing (HPC) Cluster Expansion for Computational Neuroscience Innovations in image acquisition technologies, increasing complexities in the size and scope of novel neuroscience studies, compute-intensive algorithms and an expanding gr | Health and Human Services, Department of / National Institutes of Health | 5/07/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO ,THE | $259,732 | Grant | Trans-NIH Recovery Act Research Support: The central premise underlying the San Antonio Nathan Shock Aging Center described in this proposal is that identifying the biological mechanisms that lead to senescence can best be achieved by manipulating the whole organism genetically, nutritionally, o | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| UNIVERSITY OF KENTUCKY | $241,715 | Grant | Trans-NIH Recovery Act Research Support: This is an application for a 5-year Alzheimer's Disease Core Center (ADCC) at the University of Kentucky's Sanders-Brown Center on Aging. The application consists of the Clinical, Biostatistics and Data Management, Neuropathology, Education and Informatio | Health and Human Services, Department of / National Institutes of Health | 8/18/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $3,147,857 | Grant | Trans-NIH Recovery Act Research Support: Recruitment of New Faculty in NCI Designated Cancer Centers (P30). Two awards were given:1 in the Division of Immunology(Dung Le) and the other in Radiation Oncology(Russel Hales) | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $577,917 | Grant | Trans-NIH Recovery Act Research Support: Funds will support 2 new faculty Instructors at Harvard Medical School, to serve at the New England Primate Research Center. These funds will be used to pay for an estimated 2.5 research assistants, and for the needed equipment, supplies and support to ma | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $256,000 | Grant | Trans-NIH Recovery Act Research Support: IMMUNE PRESSURE ON HIV-1 NEF BY CYTOTOXIC T LYMPHOCYTES This supplement enhances the tempo and scope of work on the parent grant AI051970 Immune Pressure on HIV-1 Nef by Cytotoxic T Lymphocytes. This parent project explores and defines the factors invo | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| MEDICAL COLLEGE OF WISCONSIN, INC., THE | $45,265 | Grant | Trans-NIH Recovery Act Research Support: We request an administrative supplement to create new summer research opportunities to encourage students to seriously pursue research careers in the health related sciences and accelerate the pace of discovery on our NIH funded project on lymphotactin, a | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $97,269 | Grant | Trans-NIH Recovery Act Research Support: Chronic pelvic pain is a major symptom of many functional pelvic disorders and may develop as a result of cross sensitization in the pelvis. The TRPV1 receptor is predominantly expressed in small diameter primary afferent neurons and was shown to contrib | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF PITTSBURGH THE | $117,503 | Grant | Trans-NIH Recovery Act Research Support: The objective of this request is to more quickly achieve the goals of our NIDDK-funded research into Adenosine Receptor Function in Bladder Uroepithelium. The purpose of this parent grant is to test the hypothesis that adenosine, acting through uroepithe | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| DUKE UNIVERSITY | $100,000 | Grant | Trans-NIH Recovery Act Research Support: Hedgehog signaling plays critical roles in development and the maintenance of stem cells, but is also reactivated during normal and pathological wound healing processes. The secreted Hedgehog ligands Sonic Hedgehog (SHhg) and Indian Hedgehog (IHhg) bind t | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $234,405 | Grant | Trans-NIH Recovery Act Research Support: This is an application for competitive revision of NIH 5R01DK078056 under NOT-OD-09-058, NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications.The ongoing epidemic of obesity in the United States represents a public he | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF PITTSBURGH THE | $80,234 | Grant | Trans-NIH Recovery Act Research Support: This is a proposal for a summer research program for undergraduate students utilizing an administrative supplement for recovery act funds (NOT-OD-09-060) for the parent grant entitled: 'High Throughput Genetic and Drug Screens for Alpha-1-Antitrypsin Defi | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| MAYO CLINIC | $31,791 | Grant | Trans-NIH Recovery Act Research Support: This grant provided a summer research experience for two summer students in health-related scientific research. | Health and Human Services, Department of / National Institutes of Health | 6/16/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $379,548 | Grant | Trans-NIH Recovery Act Research Support: We will modify our low cost retinal imaging device, the Laser Scanning Digital Camera, to investigate a low cost method to improve operator focus, measure refraction, investigate eye shape, quantify cataract, and quantify the severity of macular edema. On | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $222,054 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplement application is to provide the opportunity for a Postdoctoral fellow, Dr. Shinya Onogi, to obtain training and mentored support in the area of Image-Guided Orthopaedic Interventions by interacting with and taking part in an i | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $293,970 | Grant | Trans-NIH Recovery Act Research Support: Thromboembolic events, including stroke, are a major cause of morbidity and mortality in patients with heart failure. Even with sinus rhythm, severe heart failure confers an annual stroke risk of ~4%. While historically ascribed to blood stasis, dysfuncti | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| BETH ISRAEL DEACONESS MEDICAL CENTER INC | $266,055 | Grant | Trans-NIH Recovery Act Research Support: c-FLIP is a key anti-apoptotic factor that is over-expressed in many tumors and blocks the apoptotic machinery by interfering with FADD, caspase-8 and DR5. Significant evidence demonstrates that c-FLIP over-expression in tumors is a major cause of resista | Health and Human Services, Department of / National Institutes of Health | 7/30/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $246,367 | Grant | Trans-NIH Recovery Act Research Support: ARRA - Health Literacy and Self-Management in Heart Failure Aims To use data from the intervention arm of our heart failure self-management trial to: 1) examine the relationship between literacy and the level and rate of mastery of key learning goals for | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| EAST CAROLINA UNIVERSITY | $34,096 | Grant | Trans-NIH Recovery Act Research Support: Cyclic nucleotide signaling serves many beneficial functions in vascular smooth muscle (VSM), yet concerns over unwanted side effects from traditional cGMP and cAMP signals have warranted investigation into alternate routes for their control in VSM. Rece | Health and Human Services, Department of / National Institutes of Health | 5/31/2009 |
| CASE WESTERN RESERVE UNIVERSITY | $266,837 | Grant | Trans-NIH Recovery Act Research Support: Recent studies suggest that excess lipid accumulation may play an important role in the pathophysiology of heart failure (HF), obesity, insulin resistance and diabetes. The cellular mechanisms that determine whether excess lipid accumulation is well toler | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $132,917 | Grant | Trans-NIH Recovery Act Research Support: Most patients with early chronic myeloid leukemia (CML) achieve durable responses to treatment with imatinib, a specific inhibitor of BCR-ABL, the tyrosine kinase responsible for CML. However, relapse is frequent in patients with advanced disease and usua | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| SALUS UNIVERSITY | $213,810 | Grant | Trans-NIH Recovery Act Research Support: ANF-RGC is a receptor for the atrial natriuretic peptide, ANF, and also a membrane guanylate cyclase . ANF belongs to a family of natriuretic peptides and is the most hypotensive agent involved in cardiac and renal functions. ANF-RGC is a single transme | Health and Human Services, Department of / National Institutes of Health | 7/21/2009 |
| UNIVERSITY OF ILLINOIS | $306,200 | Grant | Trans-NIH Recovery Act Research Support: Recovery of endothelial integrity after lung vascular injury is a poorly understood aspect of vascular homeostasis. Our long term goals using molecular, cellular, and in vivo approaches are to elucidate the mechanisms of endothelial barrier repair follow | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $183,297 | Grant | Trans-NIH Recovery Act Research Support: This research focuses on two common problems that many women experience as they go through menopause, hot flashes and poor sleep. We are interested in how hot flashes affect a woman s sleep quality and whether women who have more hot flashes have poorer s | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $211,950 | Grant | Trans-NIH Recovery Act Research Support: Atherosclerosis is a disease of chronic inflammation of the arterial wall, resulting from complex interactions between modified lipoproteins, macrophages, T lymphocytes, endothelial, and smooth muscle cells. Complications of atherosclerosis such as myocar | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| UNIVERSITY OF WASHINGTON | $1,726,552 | Grant | Trans-NIH Recovery Act Research Support: Remarkable advances have been made over the last decade in our ability to analyze mRNA expression at the genome-wide level in pure cell populations. One important challenge that remains is to explore the intricate developmental, physiological and patholog | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| THE VANDERBILT UNIVERSITY | $4,737,181 | Grant | Trans-NIH Recovery Act Research Support: Research over the past 20 years has produced an explosion of new information on the genetic changes that lead to malignancy. Yet this vast trove of knowledge has not led to a corresponding increase in new modalities for cancer therapy. This is, in part, a | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $993,692 | Grant | Trans-NIH Recovery Act Research Support: Although the AIDS epidemic is nearly 30 years old, and HIV infection can generally be held in check with modern drug cocktails, Kaposi?s Sarcoma (KS), one of the original AIDS-defining opportunistic infections, is now the leading cancer reported in Southe | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF FLORIDA | $1,000,000 | Grant | Trans-NIH Recovery Act Research Support: Consistent with the ability of herpesviruses to establish persistent and latent infections, about 25% of all herpesvirus genes modulate and/or abrogate host cellular responses to viral infection. Recently, 140 microRNAs have been identified in a-, b-, and | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF WASHINGTON | $3,988,432 | Grant | Trans-NIH Recovery Act Research Support: I.Specific AimsDuring the two years of funding, we will:-Establish a multi-disciplinary and cross-institutional network of health delivery systems and researchers in Western Washington State for evaluating the comparative effectiveness of cancer diagnosti | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| WAKE FOREST UNIVERSITY | $3,978,770 | Grant | Trans-NIH Recovery Act Research Support: Prostate cancer (PCa) is the most common cancer among men in the U.S. One important strategy to address this public health concern is to prevent the disease. Two large randomized clinical trials, The Prostate Cancer Prevention Trial (PCPT) and The Reducti | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $1,548,119 | Grant | Trans-NIH Recovery Act Research Support: Diffuse intrinsic pontine gliomas are the most deadly and intractable of the pediatric brain tumors with a median overall survival of 9-10 months. Over the last 20 years, there have been numerous clinical trials studying different combinations and timing | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| FRED HUTCHINSON CANCER RESEARCH CENTER | $4,000,000 | Grant | Trans-NIH Recovery Act Research Support: Numerous genomic applications for cancer have become available offering the promise of effective and efficient cancer care tailored to the genetic profile of the patient or disease?Genomics and Personalized Medicine (GPM). The current regulatory structure | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| GROUP HEALTH COOPERATIVE | $3,992,841 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this project is to conduct comparative effectiveness research on breast cancer imaging modalities and strategies to inform evidence gaps on how to optimize breast cancer screening in community practice. The Breast Cancer Surveillance C | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF MIAMI | $1,350,523 | Grant | Trans-NIH Recovery Act Research Support: The primary goal this project is to examine the long-term effects of outpatient treatments for illicit drug using adolescents. Specifically, this study proposes to complete a follow-up assessment with a sample of 379 young adults that participated in a re | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| ABT ASSOCIATES INC. | $1,379,567 | Grant | Trans-NIH Recovery Act Research Support: This funded project aims to develop and implement an ongoing Rx Drug Diversion Surveillance Program that will provide epidemiological data at the national and sub-national levels for 2008. The principal aim will be to estimate the diversion from retail p | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| HENRY FORD HEALTH SYSTEM | $1,417,368 | Grant | Trans-NIH Recovery Act Research Support: The overarching goal of this proposal is to use evidence-based methodology to establish magnetoencephalogra-phy (MEG) as a clinical tool for evaluation and planning of surgical treatment for patients with intractable epi-lepsy with the anticipated result | Health and Human Services, Department of / National Institutes of Health | 7/19/2009 |
| NORTHWESTERN UNIVERSITY | $760,930 | Grant | Trans-NIH Recovery Act Research Support: The experiments performed during the first funded period of this project (2000-2004) led to the first evidence of a direct link between senile plaques and tau pathology in an Alzheimer's disease (AD) cell model system (Rapoport et al., 2002). This study s | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $3,067,107 | Grant | Trans-NIH Recovery Act Research Support: Intravenous (IV) administration of tissue plasminogen activator (tPA) is an effective and approved therapy for acute stroke when treatment is begun within 3 hours of symptom onset. Recent data suggest limited benefits up to 4.5 hours after symptom onset | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| NORTHWESTERN UNIVERSITY | $99,524 | Grant | Trans-NIH Recovery Act Research Support: Funds from this supplement will be used to hire a recent master's degree student as new research technician. This individual will work closely with current staff to both accelerate the pace of research of the parent grant and to accomplish the aims of thi | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| YALE UNIVERSITY | $100,000 | Grant | Trans-NIH Recovery Act Research Support: Hepatocyte apoptosis results in repair responses including hepatic stellate cell (HSC) chemotaxis, contraction and matrix remodeling. The signals from apoptotic hepatocytes which modulate these responses are poorly identified. The uric acid pathway (UAP) | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $213,073 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement provides funding to hire new graduate and post-graduate students to help accelerate and enhance the technological aims specified in the parent grant. The advancements in technology will be used to strengthen the applied port | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON | $59,421 | Grant | Trans-NIH Recovery Act Research Support: Toxins, pathogenic infection (viral and bacterial), and physical injury to the liver results in a loss of hepatic tis- ue, triggering a regenerative response to restore liver cell mass. Dysregulation in the repair process can lead o liver failure or liver | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| UNIVERSITY OF TEXAS M D ANDERSON | $345,794 | Grant | Trans-NIH Recovery Act Research Support: Inappropriate exposure to environmental agents during critical, sensitive periods of development can reprogram target tissues via epigenetic mechanisms to increase the risk for disease later in adult life. The reproductive tract is particularly sensitive | Health and Human Services, Department of / National Institutes of Health | 8/15/2009 |
| BAYLOR COLLEGE OF MEDICINE | $145,546 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this project is to define the molecular mechanisms of Cytochrome P4501A1 expression by polyclcyclic aromatic hydrocarbons (PAHs), in relation to carcinogenesis. Polycyclic aromatic hydrocarbons (PAHs) are present in cigarette smoke, particu | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| WAKE FOREST UNIVERSITY | $80,827 | Grant | Trans-NIH Recovery Act Research Support: Research in this lab and others has provided evidence for an important role for expression of glutathione S-transferases (GSTs) (Phase II detoxification) in normal cellular defenses against reactive electrophilic metabolites of carcinogens, and as part of | Health and Human Services, Department of / National Institutes of Health | 9/02/2009 |
| UNIVERSITY OF MISSISSIPPI | $86,219 | Grant | Trans-NIH Recovery Act Research Support: The Administrative Supplement proposed herein will provide: 1) funding for an additional graduate student; 2) enable increased hours of my currently part-time R&D Chemist and 3) will allow us to procure additional needed equipment and instrument time (mic | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| UNIVERSITY OF IOWA, THE | $207,481 | Grant | Trans-NIH Recovery Act Research Support: Acetylcholinesterase inhibiting pesticides (i.e., organophosphate (OP) and carbamate pesticides) are widely used in the US and worldwide. Long-term neurological and neurobehavioral health effects of exposure to these pesticides are not well characterized. | Health and Human Services, Department of / National Institutes of Health | 8/15/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $33,196 | Grant | Trans-NIH Recovery Act Research Support: Our working hypothesis in the parent grant was that inorganic arsenic (iAs) disrupts gene activation from steroid hormone-regulated gene promoters by changing patterns of histone modification. Our goal was to identify mechanisms disrupted by iAs that are | Health and Human Services, Department of / National Institutes of Health | 7/10/2009 |
| THE VANDERBILT UNIVERSITY | $101,600 | Grant | Trans-NIH Recovery Act Research Support: This research supplement request is intended to promote racial/ethinic diversity in health related research. We request two years of support for an African American graduate research assistant who is working towards a doctoral degree in the field of mole | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| OAKLAND UNIVERSITY | $28,937 | Grant | Trans-NIH Recovery Act Research Support: The objective of this award is to evaluate the role of oxidative stress in the development of human nuclear cataract, the most common type of lens opacity in older adults, and the type most likely to require surgery. The overall hypothesis of the proposal | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| NORTHWESTERN UNIVERSITY | $302,571 | Grant | Trans-NIH Recovery Act Research Support: These funds will be used to hire one new postdoctoral research fellow, retain an existing research technician and cover the costs of supplies and services necessary for the conduct of the new studies outlined in this supplement. | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $214,401 | Grant | Trans-NIH Recovery Act Research Support: Cones must function over a wide range of light intensities and a broad span of the electromagnetic spectrum. The ability to perform under such diverse conditions arises in large part from the unique set of phototransduction proteins found in cone cells. L | Health and Human Services, Department of / National Institutes of Health | 8/19/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $263,920 | Grant | Trans-NIH Recovery Act Research Support: The main body of our research focuses on how lumican a protein present in connective tissues such as the cornea regulates innate immune response and immune privilege of the cornea. Innate immune and proinflammatory responses are necessary to protect the c | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $256,430 | Grant | Trans-NIH Recovery Act Research Support: In this Supplement, funds were received to provide support for three senior postdocs. For the past 2 years, these postdocs worked on projects essential to my parent grant (EY13584-08) funded through NEI. My grant focuses on addressing 3 issues: how synapt | Health and Human Services, Department of / National Institutes of Health | 7/31/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $635,046 | Grant | Trans-NIH Recovery Act Research Support: Our work under the parent grant addresses the functions of the recently discovered melanopsin light-signaling system. The overall goal is to understand the light-response properties and biophysics of the melanopsin-expressing retinal ganglion cells (the i | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $165,482 | Grant | Trans-NIH Recovery Act Research Support: Strabismus is a misalignment of the eyes affecting 2-5% of preschool aged children. Normal binocular alignment is critical for the development and maintenance of fusion and stereopsis. For the young patient with strabismus, lack of timely or effective tre | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| MASSACHUSETTS EYE AND EAR INFIRMARY & PHYSICIAN STAFF, INC. | $503,839 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of our research is to elucidate the pathogenesis of primary open-angle glaucoma (POAG) making it possible to implement effective screening and prevention strategies and to develop novel therapies. The primary aim of this proposal is to id | Health and Human Services, Department of / National Institutes of Health | 6/30/2009 |
| UNIVERSITY OF MIAMI | $191,358 | Grant | Trans-NIH Recovery Act Research Support: This supplemental grant provides additional financial support to support the acceleration of the pace of scientific activity under the parent grant by hiring two researchers, and provides funding for the purchase of newly developed scientific equipment ac | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| UNIVERSITY OF MEDICINE AND DENTISTRY OF NJ (INC) | $429,000 | Grant | Trans-NIH Recovery Act Research Support: Atypical odontalgia (AO), also known as phantom tooth pain and trigeminal deafferentation pain, is defined by The International Association for the Study of Pain as a severe throbbing pain in a tooth without major pathology. The resemblance to toothache a | Health and Human Services, Department of / National Institutes of Health | 5/01/2009 |
| GROUP HEALTH COOPERATIVE | $448,320 | Grant | Trans-NIH Recovery Act Research Support: Consistent with the goals of the NIDCR R21 mechanism, the main objectives of this grant application are to collect pilot feasibility data to support the development of an oral health promotion program designed to be integrated into standard smoking cessa | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| TUFTS MEDICAL CENTER PARENT, INC. | $427,588 | Grant | Trans-NIH Recovery Act Research Support: Tanycytes are specialized cells that line the floor and ventrolateral walls of the third ventricle. Compelling evidence suggests they have an important role in generating thyroid hormone due to high expressionof type 2 iodothyronine deiodinase, an enzyme | Health and Human Services, Department of / National Institutes of Health | 5/08/2009 |
| CHRISTIANA CARE HEALTH SERVICES, INC. | $302,750 | Grant | Trans-NIH Recovery Act Research Support: A Department of Health and Human Services grant to evaluate Troponin elevation in Patients with Acute Coronary Syndrome & Decreased Kidney Function. | Health and Human Services, Department of / National Institutes of Health | 9/02/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $346,500 | Grant | Trans-NIH Recovery Act Research Support: We have completed this single center randomized trial to test the effectiveness of daily supplementation of omega-3 fatty acids (3.6 g DHA/EPA) over 3 months in 31 adults with diabetes and proteinuria, on urine protein excretion. | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| BETH ISRAEL DEACONESS MEDICAL CENTER INC | $467,500 | Grant | Trans-NIH Recovery Act Research Support: Intestinal inflammation involves two stages: early inflammatory phase and later resolution phase. The early phase is characterized by pathogen-induced activation of various cell types and release of numerous inflammatory mediators which then cause infiltr | Health and Human Services, Department of / National Institutes of Health | 5/26/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $488,353 | Grant | Trans-NIH Recovery Act Research Support: Lysosomal storage diseases are a group of multisystem disorders characterized by the common pathology of abnormal accumulation of storage material in lysosomes. Lysosomal storage diseases often affect the central nervous system and cause significant neuro | Health and Human Services, Department of / National Institutes of Health | 5/15/2009 |
| UNIVERSITY OF PITTSBURGH THE | $411,765 | Grant | Trans-NIH Recovery Act Research Support: The objective of this funded study is to develop new scientific tools to investigate the relatedness of neural, biochemical, and vascular processes in the brain. This study will develop and advance neuroimaging techniques to simultaneously measure neuron | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $408,375 | Grant | Trans-NIH Recovery Act Research Support: This project is being supported with funds from the American Recovery and Reinvestment Act, which may involve a reduction in the research aims and scope. If necessary, a revised abstract will be posted soon and this notice removed. DESCRIPTION (provided | Health and Human Services, Department of / National Institutes of Health | 5/15/2009 |
| ALLEGHENY-SINGER RESEARCH INSTITUTE | $415,950 | Grant | Trans-NIH Recovery Act Research Support: This proposal addresses a problem central to the study of focal ischemic stroke therapy: the blood- brain barrier (BBB) breakdown via vasogenic edema that restricts the window of tPA administration. We will study the initial BBB disruption after which the | Health and Human Services, Department of / National Institutes of Health | 6/15/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $364,000 | Grant | Trans-NIH Recovery Act Research Support: The leukodystrophies are a group of disorders that affect myelin. Most of the leukodystrophies are hereditary and cause progressive degeneration of the white matter. Currently, there are no cures for any of the leukodystrophies. The focus of this project | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| DUKE UNIVERSITY | $428,508 | Grant | Trans-NIH Recovery Act Research Support: Primary malignant brain tumors, like glioblastoma (GBM), remain universally fatal. Like most neoplasms, they develop through the acquisition of multiple genetic alterations that lead to a heterogeneous deregulation of cell signaling pathways. Despite this | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $516,704 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this project is to develop a multifocal optical coherence microscope (OCM). The proposed OCM will allow noninvasive imaging of unstained biological specimens, with millisecond temporal resolution and sub-cellular spatial resolution in three | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| THE MIRIAM HOSPITAL | $930,320 | Grant | Trans-NIH Recovery Act Research Support: The goal of this project is to develop and test an innovative web-based program that would provide an accessible and effective approach for obese patients who have been encouraged by their physician to lose weight. The program will use Web-based interacti | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF UTAH, THE | $997,001 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): This application addresses broad Challenge Area (04), Clinical Research, and specific Challenge Topic 04-HL-103: assess the role of leukocyte interaction with platelets, erythrocytes, and endothelium in the pathogenesi | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF KENTUCKY | $480,899 | Grant | Trans-NIH Recovery Act Research Support: Improving clinical outcomes in critically ill patients with respiratory failure. Over the past two decades a great deal has been learned about the basic physiology of the breathing muscles and a number of pathophysiological conditions, including sepsis, h | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $1,000,000 | Grant | Trans-NIH Recovery Act Research Support: Acquired lymphatic vascular dysfunction (lymphedema) is a common, chronic, debilitating disease that is frequently under-recognized or misdiagnosed, and many patients never receive treatment. The inability to accurately predict high- risk individuals is a | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF WASHINGTON | $998,292 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (04) Clinical Research, specific Challenge Topic 04-HL-104'Perform secondary analyses of existing data to answer important clinical and preventive medicine researchquestions.' We propose to use existing data | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| NORTHWESTERN UNIVERSITY | $994,105 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (15): Translational Science, and specific Challenge Topic, 15-HL-101: Develop improved biocompatible surfaces for implantable blood-contacting medical devices. The broad, long-term objective of this proposal | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| GROUP HEALTH COOPERATIVE | $992,334 | Grant | Trans-NIH Recovery Act Research Support: This project launches a collaborative effort to advance adoption within the HMO Cancer Research Network (CRN) of G?industrial-strengthG? natural language processing (NLP) systems useful for mining valuable, research-grade information from unstructured cli | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF MARYLAND | $682,630 | Grant | Trans-NIH Recovery Act Research Support: Visual and interactive solutions for specifying search and reviewing results can dramatically increase the benefits of EHR databases, leading to improved clinical research and patient care.-? -?Novel interface designs are needed for 1) interactive query i | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $997,452 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (15) Translational Science and specific Challenge Topic, 15-DA-101*: Novel Approaches to Improve Immunogenicity of Vaccine against Small Molecules. The specific aim of this proposal is to provide proof of co | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| FRIENDS RESEARCH INSTITUTE, INC | $990,091 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (05): Comparative Effectiveness Research, and specific Challenge Topic (05-DA-104): Comparing Drug Treatment Effectiveness in Ethnic Minority Populations Background: Although there is relatively little diffe | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| LOYOLA UNIVERSITY | $832,452 | Grant | Trans-NIH Recovery Act Research Support: The overall purpose of this award is to provide funding for a new faculty member, and also to establish Loyola's Alcohol Research Center (LARC). These funds will enable us to better direct our alcohol interests in the direction of alcohol and injury. A | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY | $1,544,000 | Grant | Trans-NIH Recovery Act Research Support: This application was submitted by the David H. Koch Institute for Integrative Cancer Research at MIT (Kl), which succeeded the MIT Center for Cancer Research (CCR) in 2007. Funds were requested to hire an MD/PhD physician-scientist. Dr. Matthew Vander Hei | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF KENTUCKY | $1,439,136 | Grant | Trans-NIH Recovery Act Research Support: The strategic plan of the University of Kentucky (UK) P30 application in response to RFA-OD-09-005 is to provide support for the recruitment of 2 junior investigators who will be immersed into a highly collaborative, interdisciplinary group of investigato | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| TEXAS A&M UNIVERSITY SYSTEM,THE | $1,375,946 | Grant | Trans-NIH Recovery Act Research Support: This proposed project, entitled 'Baylor's Program in Bioengineering Sciences and Translational Research (B-BEST)', will provide support for the hiring and development of two new faculty with expertise in Bioengineering Sciences and Translational Research. | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $732,517 | Grant | Trans-NIH Recovery Act Research Support: We propose to recruit an outstanding junior scientist as a tenure track assistant professor to augment and strengthen our core center In tumor virology. To date, specific human tumor viruses have been causally associated with at least 15-20% of all human | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF ARIZONA | $710,484 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): We propose to establish a Center for Systems Biology to promote the application of state of the art high- throughput technologies and further a multidisciplinary, systems approach to biomedical research at the Universi | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| BAYLOR COLLEGE OF MEDICINE | $996,476 | Grant | Trans-NIH Recovery Act Research Support: 'The purpose of this grant is to improve the prevention of cardiovascular disease by using recent genetic discoveries to identify who is at risk of developing a heart attack and by improved understanding of the genes that control the levels of fats (trigl | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| THE VANDERBILT UNIVERSITY | $640,445 | Grant | Trans-NIH Recovery Act Research Support: Salivary carcinoma is a devastating disease whose primary treatment often relies on surgery. Cure rates are unacceptable and for patients that cannot be treated surgically due to tumor spread or patient characteristics, the chance of cure is very low. Ver | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $993,031 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (15): Translational Science 15-DK-102. Develop improved animal models of National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Dysfunction of the parathyroid glands and the production of | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| MAYO CLINIC | $924,609 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (05) Comparative Effectiveness Research and specific Challenge Topic, 05-EB-101* - Comparative Effectiveness of Advanced Imaging Procedures. Advances in cross-sectional imaging have revolutionized the medica | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF PITTSBURGH THE | $850,000 | Grant | Trans-NIH Recovery Act Research Support: This research proposal addresses the topic of how to clinically evaluate cell therapies which are being investigated for a variety of cardiovascular applications. Congestive heart failure resulting from myocardial infarction and subsequent adverse left | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| YALE UNIVERSITY | $2,245,836 | Grant | Trans-NIH Recovery Act Research Support: This proposal is in response to a request for applications to address ''''Genomic Profiling of Mental Disorders,'''' and proposes intensive genomic profiling and functional analysis of Contactin Associated Protein 2 (CNTNAP2) as well as the presynaptic cy | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF IOWA, THE | $498,000 | Grant | Trans-NIH Recovery Act Research Support: Rituximab is widely used as a therapy for B cell malignancies. Despite its certain clinical value, the mechanisms responsible for the clinical anti-tumor effect of rituximab and other monoclonal antibodies (mAb) are unclear. Both antibody-dependent cellul | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| NORTHWESTERN UNIVERSITY | $639,246 | Grant | Trans-NIH Recovery Act Research Support: The overarching goal for this project is to provide an efficient agent for the prevention of colitis-induced cancer. Chronic colitis is a well-recognized risk factor of colon cancer; an increase in colitis-induced aberrant arachidonic acid (AA) metabolite | Health and Human Services, Department of / National Institutes of Health | 5/12/2009 |
| THE JACKSON LABORATORY | $722,100 | Grant | Trans-NIH Recovery Act Research Support: Chromosomal instability is a major hallmark of many cancers, and chromosome aberrations can be important prognostic markers, with greater instability usually corresponding to poorer outlook. Unfortunately, the underlying processes that prevent or promote | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $666,577 | Grant | Trans-NIH Recovery Act Research Support: Metastatic melanoma is an aggressive tumor with a poor prognosis. Critical biologic features of melanoma metastasis are the acquisition of migratory competence, growth factor independence, and invasive potential. In an attempt to identify genes that contr | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $1,197,369 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Adjuvant systemic therapy, including chemotherapy, hormonal therapy, and trastuzumab, markedly reduces the risk of metastatic recurrence and death for selected patients with breast cancer. Guideline-concordant use of c | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $695,927 | Grant | Trans-NIH Recovery Act Research Support: A hallmark of solid tumors is the requirement to adapt to, and eventually overcome the stressful environment of low oxygen, growth factors, glucose and pH in the growing tumor mass. The requirement for neoangiogenesis to support tumor growth is now well e | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY | $485,241 | Grant | Trans-NIH Recovery Act Research Support: We propose to evaluate the potential of integrase-defective lentiviral vectors (ID-LV) for the generation of a protective immune response in the mouse model of influenza type A virus infection using the internal nucleoprotein as antigen. We will compare t | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| THE VANDERBILT UNIVERSITY | $438,917 | Grant | Trans-NIH Recovery Act Research Support: The main goal of this application is to design an effective vaccine against HIV infection. Our group has made novel changes to a vaccine (BCG) commonly used to vaccinate newborn children against tuberculosis. These changes make this vaccine more effective | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF HAWAII SYSTEMS | $399,100 | Grant | Trans-NIH Recovery Act Research Support: We aim to understand the mechanisms contributing to pathogenesis of severe disease. Our study findings are directly applicable to dengue vaccine design that may improve safety by avoiding potential cross-reactivity in T cell responses. | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $440,000 | Grant | Trans-NIH Recovery Act Research Support: Our goal in this study is to discovery of diagnostic and prognostic urinary non- invasive biomarkers for acute rejection in pediatric kidney transplantation. Graft survival after kidney transplantation, the treatment of choice for children with end stage | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| HEALTH RESEARCH, INC. | $352,718 | Grant | Trans-NIH Recovery Act Research Support: There is a critical need to better understand the enzootic transmission cycles of West Nile virus (WNV), particularly as relates to understanding the role that host genes play in determining why different species and strains of mosquito vary in their susc | Health and Human Services, Department of / National Institutes of Health | 5/11/2009 |
| UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | $408,167 | Grant | Trans-NIH Recovery Act Research Support: This project is designed to study DNA recombinational repair pathways in the human gastric pathogen Helicobacter pylori that contribute to the bacterial survival and genetic diversity. Gene-targeted mutant strains defective in DNA recombinational repair | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $373,309 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Toxoplasma gondii and Listeria monocytogenes are intracellular pathogens classified as NIAID category B priority agents. Both organisms can lead to significant disease and mortality in immunodeficient or immunocompeten | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| UNIVERSITY OF MARYLAND | $412,500 | Grant | Trans-NIH Recovery Act Research Support: Allergic asthma is characterized by exaggerated Th2 inflammation resulting from interaction between DC and T cells. Molecules acting in this interaction, regulating cell activation and differentiation are desirable therapeutic targets. This proposal aims | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| SOUTHERN ILLINOIS UNIVERSITY | $400,125 | Grant | Trans-NIH Recovery Act Research Support: This grant project will determine how ginseng and its constituents contribute to the complementary effectiveness of ginseng during doxorubicin treatment for breast cancer. For Specific Aim #1, female nude mice will be inoculated with human breast cancer M | Health and Human Services, Department of / National Institutes of Health | 4/28/2009 |
| ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE | $343,089 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): We have developed an intracellular immunization strategy with a genetically engineered human antibody clone as a novel antiviral therapy against the hepatitis C virus. This antibody clone targets the HCV NS3 protein, | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $363,000 | Grant | Trans-NIH Recovery Act Research Support: There is a need for chemopreventive agents that prevent lung cancer. We propose five Aims: Specific Aim 1: Demonstrate that the combined use of chemopreventive agents has greater efficacy in preventing lung tumors than the individual agents acting alone. | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| SOUTH CAROLINA RESEARCH FOUNDATION | $348,274 | Grant | Trans-NIH Recovery Act Research Support: CURCUMIN AND QUERCETIN IN COLON CANCER: ROLE OF MACROPHAGE-INDUCED INFLAMMATION Colorectal cancer (CRC) is the second leading cause of cancer death in the United States and the fourth most commonly diagnosed cancer. There is increasing recognition of diet | Health and Human Services, Department of / National Institutes of Health | 5/15/2009 |
| RESEARCH TRIANGLE INSTITUTE | $404,548 | Grant | Trans-NIH Recovery Act Research Support: The goal of this project is to develop a new method for studying how dietary supplements affect the epigenome, biochemical reactions at the level of the DNA that turn genes on and off. This research will develop a method for uncovering genes that are most | Health and Human Services, Department of / National Institutes of Health | 5/07/2009 |
| HEALTH RESEARCH, INC. | $647,474 | Grant | Trans-NIH Recovery Act Research Support: The anti hormonal drug tamoxifen is approved for the treatment of women with early and advanced and early stage estrogen receptor (ER)-positive breast cancer. Tamoxifen is known to exert its effects on breast cancer cells by binding to the estrogen recept | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $373,890 | Grant | Trans-NIH Recovery Act Research Support: There are over 10 million cancer survivors whose needs for psychosocial care are not being met. Although some supportive-educative programs exist, they are expensive to deliver and do not address communication problems of patients and their family caregiv | Health and Human Services, Department of / National Institutes of Health | 5/05/2009 |
| WAKE FOREST UNIVERSITY | $358,160 | Grant | Trans-NIH Recovery Act Research Support: A better understanding of the limitations of current physical assessment measures is needed. Both random and systematic errors in an assessment method can have a large impact on estimating the relationship between physical activity and disease. By using a | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| BAYLOR COLLEGE OF MEDICINE | $371,470 | Grant | Trans-NIH Recovery Act Research Support: The goal is to develop a novel virus-like particle (VLP) stimulated dendritic cell (DC) immunotherapeutic vaccine for pancreatic cancer. This project is designed to test a central hypothesis that silencing the master immune negative regulator MSK (mitogen | Health and Human Services, Department of / National Institutes of Health | 5/14/2009 |
| FORSYTH DENTAL INFIRMARY FOR CHILDREN | $919,338 | Grant | Trans-NIH Recovery Act Research Support: Despite many studies that have aimed to alleviate the effects of periodontal and endodontic disease there is still an urgent need to improve the oral health of those suffering from oral infectious or inflammatory diseases. Such translational application o | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $912,668 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (03): Biomarker Discovery and Validation, and specific Challenge Topic 03-DK-103: Identify the normal and diseased proteome of subcellular organelles ofrelevance to NIDDK diseases. Mitochondrial dysf | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| SAINT LOUIS UNIVERSITY | $1,000,000 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (02) Bioethics and specific Challenge Topic, 02-DK-105: Allocation of Scarce Transplanted Organs.This application addresses broad Challenge Area (02) Bioethics and specific Challenge Topic, 02-DK-105. Organ | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE | $987,682 | Grant | Trans-NIH Recovery Act Research Support: This grant application addresses broad Challenge Area (04): Clinical Research and specific challenge topic 04-AI-101: Develop novel methods and address key questions in mucosal immunology. The proposal draws from strong preliminary data from our laborator | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $605,549 | Grant | Trans-NIH Recovery Act Research Support: Acute kidney injury has high morbidity and high mortality. There is no specific and effective treatment at the present time. Stem cells offer therapeutic potential for kidney disease. The goal of this application is to develop cell therapeutic agents from | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $999,999 | Grant | Trans-NIH Recovery Act Research Support: In this context, this feasibility trial is designed to begin to directly address the critically important questions that clinicians face in selecting the best approach for a given T2DM patient, as well those confronting health care payers in their decisio | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| VETERANS MEDICAL RESEARCH FOUNDATION OF SAN DIEGO | $876,577 | Grant | Trans-NIH Recovery Act Research Support: Statement of the Challenge Area and the specific Challenge Topic: The broad Challenge Area (04) Clinical Research and the specific Challenge Topic (AA-101) Medication Development for Hepatic Fibrosis will be addressed with our project entitled 'C/EBP beta | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $4,397,108 | Grant | Trans-NIH Recovery Act Research Support: Abstract The Omega-3 Fatty Acids for Prevention of Post-Operative Atrial Fibrillation (OPERA) Trial is a funded, double-blind, placebo-controlled, multicenter, randomized clinical trial testing the hypothesis that peri-op fish oil will reduce occurrence o | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| WASHINGTON UNIVERSITY, THE | $1,924,016 | Grant | Trans-NIH Recovery Act Research Support: The ultimate goal of this 2 year NIH-NHLBI RC2 GO Grant (RFA-OD-09-004), Comparative Effectiveness, is to develop a websystem that facilitates Community Based Participatory Research (CBPR) to identify populations underrepresented in research. This effort | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $2,343,137 | Grant | Trans-NIH Recovery Act Research Support: Genome-wide association (GWA) studies have made great progress in the identification of regions that are likely to contain genetic variants contributing to the risk of cardiovascular, lung and blood diseases. Despite these successes, variants identified t | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $1,337,407 | Grant | Trans-NIH Recovery Act Research Support: To support hiring and provide a start-up package for an outstanding clinician scientist as a tenure-track faculty at UCLA and to develop resources to support research projects within the context of a specialized new biomedical research core center. The ce | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| SAN DIEGO STATE UNIVERSTIY FOUNDATION | $982,189 | Grant | Trans-NIH Recovery Act Research Support: Screening, Brief Intervention, and Referral to Treatment (SBIRT) is a comprehensive, integrated public health approach to identify and deliver a spectrum of early detection and treatment services for substance use in general medical care settings. The eff | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF MASSACHUSETTS | $976,217 | Grant | Trans-NIH Recovery Act Research Support: Title: Production of new animal models to determine how CTLA-4 contributes to T1D susceptibility The genetic basis of T1D has been intensely investigated. More than 20 and 5 T1D-susceptibility genes have been mapped in rodents and humans respectively, wit | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $1,000,000 | Grant | Trans-NIH Recovery Act Research Support: This grant award is investigating the effects of the Wireless Pain Intervention Program. The program has three features that consist of a 1) participants (10 to 17 years) using using wireless technology(iPhone) to access an electronic diary with questio | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| YALE UNIVERSITY | $82,556 | Grant | Trans-NIH Recovery Act Research Support: Hepatitis C virus (HCV) is an RNA virus that chronically infects an estimated 120-170 million people worldwide, with up to 20% developing liver diseases such as cirrhosis and hepatocellular carcinoma. The ability of HCV to establish life-long infection at | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| YALE UNIVERSITY | $60,936 | Grant | Trans-NIH Recovery Act Research Support: This proposal combines behavioral, biochemical and molecular approaches to examine the neurobiological influence of leptin on relapse to cocaine-seeking. The interaction between leptin, a peripheral hormone produced in fat cells, and relapse of cocaine-se | Health and Human Services, Department of / National Institutes of Health | 5/14/2009 |
| UNIVERSITY OF NEBRASKA | $1,138,814 | Grant | Trans-NIH Recovery Act Research Support: Support for recruitment of a tenure track faculty member, Lie Gao, M.D.,Ph.D. for salary support and startup funds to elevate Dr. Lie Gao to a tenure tract Assistant Professor in the Department of Cellular and Integrative Physiology at the University of N | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| TRUDEAU INSTITUTE INC | $445,000 | Grant | Trans-NIH Recovery Act Research Support: Protective immunity depends on memory CD4 T cells generated during initial encounter with pathogen. Na+?ve CD4 T cells respond vigorously to influenza (Flu) virus, expanding and differentiating into a large effector population that participates in Flu cle | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| YALE UNIVERSITY | $618,142 | Grant | Trans-NIH Recovery Act Research Support: Metastasis of tumor cells to other tissues and organs is the leading cause of mortality from breast cancer. Metastatic breast cancer cells escape the tumor and enter the bloodstream by forming filamentous-actin-rich protrusions called invadopodia that dig | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| YALE UNIVERSITY | $774,560 | Grant | Trans-NIH Recovery Act Research Support: During natural visually guided behavior people are routinely exposed to a vast and potentially overwhelming amount of visual information. The human brain is simply unable to encode and respond to each and every image that enters the eyes. Visual attention | Health and Human Services, Department of / National Institutes of Health | 5/14/2009 |
| BAYLOR COLLEGE OF MEDICINE | $614,000 | Grant | Trans-NIH Recovery Act Research Support: Many organelles exist in an equilibrium of fragmentation into smaller units (e.g. during mitosis) and fusion into larger structures. How are size, copy number and shape of an organelle determined and how are the elementary processes of membrane fission an | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $807,566 | Grant | Trans-NIH Recovery Act Research Support: Autism spectrum disorders (ASDs) are a heterogeneous group of neurodevelopmental disorders characterized by three domains of behavioral deficits: impaired social interaction, delayed language development, and motor stereotypy. Although etiologies underly | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| YALE UNIVERSITY | $164,912 | Grant | Trans-NIH Recovery Act Research Support: Systemic lupus erythematosus (SLE) is a life-threatening disease, in which antibodies against self-proteins damage various organs. The self-proteins that are responsible for the initiation of SLE still remain unknown. We have shown that posttranslationall | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF WYOMING | $143,000 | Grant | Trans-NIH Recovery Act Research Support: The funding supports studies on offspring skeletal muscle development of baboon as affected by maternal nutrient deficiency. Fetal nutrient restriction results from many conditions in pregnancy, e. g. maternal malnutrition, reduced placenta efficiency, ad | Health and Human Services, Department of / National Institutes of Health | 8/26/2009 |
| UNIVERSITY OF ARKANSAS SYSTEM | $415,352 | Grant | Trans-NIH Recovery Act Research Support: Microglia in Chronic Visceral Pain Hypersensitivity of visceral organs is a main characteristic of numerous functional digestive disorders including irritable bowel syndrome (IBS): a debilitating disorder that affects up to 15% of the US population and on | Health and Human Services, Department of / National Institutes of Health | 5/25/2009 |
| UNIVERSITY OF MASSACHUSETTS | $451,688 | Grant | Trans-NIH Recovery Act Research Support: Development of non-invasive technology for islet imaging is a major yet unattained goal for monitoring islet cell mass during the progression of diabetes, for determining the efficacy of therapeutics, and the survival of islets following curative transpla | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| MEDICAL COLLEGE OF WISCONSIN, INC., THE | $230,954 | Grant | Trans-NIH Recovery Act Research Support: Primary systemic amyloidosis is a plasma cell dyscrasia that is often fatal especially if there is cardiac involvement. Untreated, patients with heart failure have median survival of 4-8 months, yet these patients are often ineligible for life-saving hig | Health and Human Services, Department of / National Institutes of Health | 5/15/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $319,311 | Grant | Trans-NIH Recovery Act Research Support: PPM-PREP: PEER-MENTORED PREPAREDNESS FOR ADULTS WITH DEVELOPMENTAL DISABILITIES The project will be testing the feasibility and determining the effect size of a peer-mentored, class-room based program for improving disaster preparedness among adults with | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE | $532,889 | Grant | Trans-NIH Recovery Act Research Support: Somatic stem cells appear to have their greatest impact on stroke therapeutics not by literally replacing cells but by protecting host neural cells & circuitry from progressive damage as well as catalyzing endogenous host regenerative responses. When such | Health and Human Services, Department of / National Institutes of Health | 6/12/2009 |
| OKLAHOMA STATE UNIVERSITY | $92,824 | Grant | Trans-NIH Recovery Act Research Support: This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The proposed research explores the role of IpaD in the ability of bacterial pathogens, such as Shigella, to invade and spread throughout epithelial cell mono | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $51,662 | Grant | Trans-NIH Recovery Act Research Support: The most resistant form of tuberculosis (TB), extensively drug resistant tuberculosis (XDR-TB) is defined as resistance to Isoniazid, rifampin, fluoroquinolones and one of three injectable second-line anti-TB agents. Drug-resistant TB arises when poor adh | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE | $496,917 | Grant | Trans-NIH Recovery Act Research Support: This revised G20 application is submitted to enhance the Biological Resources Facility (BRF) of Rosalind Franklin University of Medicine and Science (RFUMS). The Board of Trustees recruited a new President to RFUMS in 2002-2003. As one of the new administ | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| VIRGINIA COMMONWEALTH UNIVERSITY | $4,990,000 | Grant | National Center for Research Resources, Recovery Act Construction Support: Over the past 25 years, the Departments of Physiology and Internal Medicine (Division of Cardiology) at Virginia Commonwealth University (VCD) have maintained a highly productive research program in cardiovascular injury and r repair. An established core gr... Show more | Health and Human Services, Department of / National Institutes of Health | 8/29/2009 |
| COLORADO STATE UNIVERSITY | $1,998,452 | Grant | Trans-NIH Recovery Act Research Support: The global epidemic of tuberculosis continues unabated. A particularly dangerous family of clinical strains is the 'W-Beijing' family, many of which are highly drug resistant [MDR]. The substantial and relatively rapid transmission of these strains across | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $2,317,500 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (Provided by the applicant) Abstract: HIV/AIDS is one of the most destructive pandemics in human history, responsible for more than 25 million deaths. More than 30 million people live with limited or no access to therapeutic treatments, mainly | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF PITTSBURGH THE | $2,272,500 | Grant | Trans-NIH Recovery Act Research Support: Regenerative medicine largely relies on cell-based therapy for treatment of degenerative diseases such as diabetes, heart failure, and Parkinson's disease. Embryonic stem cells and recently established induced pluripotent stem cells will be able to contri | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $2,400,000 | Grant | Trans-NIH Recovery Act Research Support: The composition and function of the human intestinal microbiota is tightly linked to diverse aspects of host biology. Several diseases, including obesity and inflammatory bowel diseases, have been associated with altered microbiota composition. While m | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| THOMAS JEFFERSON UNIVERSITY | $849,750 | Grant | Trans-NIH Recovery Act Research Support: In the previous funding cycle, we have found that EAAT2 is selectively cleaved by caspase-3 in the spinal cord of mutant SOD1 (SOD1-G93A) transgenic mice model of ALS and that the C-terminal EAAT2 fragment derived from this cleavage (termed CTE fragment) | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $914,640 | Grant | Trans-NIH Recovery Act Research Support: This project will evaluate a non-invasive PET method for assessment of tumor perfusion using generator- produced copper-62. The proposed method will be suitable for implementation at any clinical PET center in the U.S., complementing current clinical whol | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| TREATMENT RESEARCH INSTITUTE | $847,194 | Grant | Trans-NIH Recovery Act Research Support: There are well documented problems in adapting evidence-based treatments (EBT's) to fit the real world of addiction treatment programs - most EBT's are too complex and require too much training and ongoing clinical supervision to be practical for communit | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| BAYLOR UNIVERSITY | $132,175 | Grant | Trans-NIH Recovery Act Research Support: For this project, we seek to do a secondary data analysis of the National Longitudinal Study of Adolescent Health (Add Health) data in order to understand the reason why individual differences (i.e., cognitive ability and personality) are related to healt | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF CINCINNATI | $156,916 | Grant | Trans-NIH Recovery Act Research Support: Thyroid diseases affect over 25 million Americans and constitute the second most common group of metabolic disorders. Thyroid hormone (TH) is critical for growth, development, and metabolism, and works by binding TH receptors in the cell nucleus and chang | Health and Human Services, Department of / National Institutes of Health | 4/29/2009 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $158,500 | Grant | Trans-NIH Recovery Act Research Support: The incidence of late preterm births (defined as births at 34 0/7 to 36 6/7 wk gestation) have been steadily increasing over the past decade and account for the ~ 75% of all preterm births. Respiratory morbidity from disorders of transition including pulm | Health and Human Services, Department of / National Institutes of Health | 4/30/2009 |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY | $823,051 | Grant | Trans-NIH Recovery Act Research Support: This application addresses Broad Challenge Area (15) Translation Science and Specific Challenge Topic: 15-NS-103 Demonstration of 'proof-of-concept' for a new therapeutic approach in a neurological disease. Alzheimer's disease (AD) is an irreversible neur | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $950,257 | Grant | Trans-NIH Recovery Act Research Support: Recent research has shown evidence of neural plasticity at older ages and that cognitive exercise or training may help performance and delay age-related cognitive decline and various forms of dementia. Previous approaches to cognitive training have genera | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| NEW YORK UNIVERSITY (INC) | $898,590 | Grant | Trans-NIH Recovery Act Research Support: 'TITLE: A reconstructed skin model for development of treatments for albinism.This application addresses the broad challenge area (15) Translational Science and the specific challenge topic, 15-OD (ORDR)-101 G?Pilot projects for prevention, early detectio | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $1,000,000 | Grant | Trans-NIH Recovery Act Research Support: Rheumatoid arthritis (RA) is the most common inflammatory joint disease of autoimmune etiology and remains a cause of substantial morbidity and mortality. Effective treatment of RA has been impeded by a paucity of diagnostic/predictive biomarkers of RA, l | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| CARNEGIE MELLON UNIVERSITY | $447,911 | Grant | Trans-NIH Recovery Act Research Support: The major focus of the project is to determine whether immune cell senescence (as assessed by telomere length) plays an important role in our ability to fight off infection. Because life stress has been found to be associated with greater senescence, we | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| LOUISIANA STATE UNIVERSITY SYSTEM | $64,444 | Grant | Trans-NIH Recovery Act Research Support: Stroke is the third leading cause of death and the leading cause of adult disability in the United States. It especially targets the elderly population which experiences a higher overall incidence and neurological detriment as a result of stroke. As of | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| UNIVERSITY OF CHICAGO, THE | $68,815 | Grant | Trans-NIH Recovery Act Research Support: This project aims to examine the trafficking and processing of the amyloid precursor protein (APP) in neurons. APP gives rise the amyloid-p protein (AS),is mutated in a subset of Alzheimer's disease patients, and is the enzymatic substrate of the protease | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $82,556 | Grant | Trans-NIH Recovery Act Research Support: The number of pregnant women using methamphetamine (MA) is increasing. Exposure to MA in utero leads to neurological and cognitive deficits in infants that persist into adulthood. Yet, the neurobiology underlying these deficits is not known. Understanding | Health and Human Services, Department of / National Institutes of Health | 5/07/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $56,580 | Grant | Trans-NIH Recovery Act Research Support: CD4+ T cells regulate multiple aspects of adaptive immune responses to intracellular pathogens through the secretion of pro-inflammatory cytokines. Innate cells of the immune system detect and respond to pathogens by secreting a number of innate cytokines | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF NEBRASKA | $63,468 | Grant | Trans-NIH Recovery Act Research Support: Human herpes virus-8 (HHV-8) or Kaposi's sarcoma associated herpes virus is the etiologic agent of Kaposi's Sarcoma (KS), a hallmark for AIDS patients. Even in the era of antiviral therapy (ARV), KS is still very common in sub-Saharan Africa, where ARV is | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| MEHARRY MEDICAL COLLEGE | $71,132 | Grant | Trans-NIH Recovery Act Research Support: Previous studies have shown that HIV-1 preferentially buds from cholesterol-rich microdomains called lipid rafts, and that cholesterol is required for HIV infectivity and structural integrity. Moreover, the presence of cholesterol is also required both fo | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $82,556 | Grant | Trans-NIH Recovery Act Research Support: The long term objective of this study is to identify novel molecules as potential clinical candidates for the inhibition of HIV-1 integrase (IN) and the prevention of HIV-1 replication. Cellular chromatin-tethering LEDGF fusion protein was reported to be | Health and Human Services, Department of / National Institutes of Health | 7/21/2009 |
| UNIVERSITY OF MARYLAND | $56,776 | Grant | Trans-NIH Recovery Act Research Support: Lassa virus (LASV) is the causative agent of Lassa Fever (LF), a zoonotic viral hemorrhagic fever endemic in West Africa responsible for wide spread disease and significant morbidity and mortality. There currently exists no vaccine against LF, while the n | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF SOUTH FLORIDA | $60,352 | Grant | Trans-NIH Recovery Act Research Support: Malaria is a devastating disease that kills 2-3 million people and is responsible for 300-500 million clinical infections each year. This disease is the result of infection with apicomplexan parasites of the genus Plasmodium and is transmitted to humans b | Health and Human Services, Department of / National Institutes of Health | 7/30/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $80,990 | Grant | Trans-NIH Recovery Act Research Support: Understanding the immune response to viral infection is key to developing strategies for protection in terms of both vaccination and treatment.In this proposal, we will examine the link between the number of CD8+ T cells specific for Epstein-Barr virus (E | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| UNIVERSITY OF MEDICINE AND DENTISTRY OF NJ (INC) | $60,636 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this award is to provide financial support to myself, Jessica Mann, a third year graduate student. The money will help supplement my stipend and university fees as I work on defining the role of minor pseudopilins during natural transforma | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $61,684 | Grant | Trans-NIH Recovery Act Research Support: Neuroimaging studies have identified both macrostructural and microstructural evidence of white matter (WM) tissue maturation continuing through adolescence and into young adulthood. WM development is important for smooth and efficient communication betwe | Health and Human Services, Department of / National Institutes of Health | 5/14/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $69,756 | Grant | Trans-NIH Recovery Act Research Support: Novel forms of reward-related plasticity in the visual cortex are not only intriguing in terms of basic sensory coding mechanisms, but have direct relevance to our understanding of cue-drug association, an important facet of the complex problem of drug ad | Health and Human Services, Department of / National Institutes of Health | 5/07/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $41,976 | Grant | Trans-NIH Recovery Act Research Support: Aggregatibacter actinomycetemcomitans (Aa) is a periodontal pathogen that causes Localized Aggressive Periodontitis (LAP) and can cause systemic diseases, such as Infective Endocarditis and abscesses. A striking phenotype of clinical isolates of Aa is ten | Health and Human Services, Department of / National Institutes of Health | 5/20/2009 |
| NORTHWESTERN UNIVERSITY | $105,520 | Grant | Trans-NIH Recovery Act Research Support: The focus of this proposal is to further characterize the mechanism of RHO inactivation by RID. My two specific aims are to 1) Isolate regions and residues of the MARTXVc RID membrance localization doamin which are important for function. 2) Identify bind | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| UNIVERSITY OF CHICAGO, THE | $59,402 | Grant | Trans-NIH Recovery Act Research Support: A20 is an anti-inflammatory protein that is required for terminating responses upstream of NF-kB activation. This is highlighted by the finding that mice lacking A20 develop a systemic inflammatory disease that leads to their premature death. The mechanis | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $102,208 | Grant | Trans-NIH Recovery Act Research Support: Influenza A nonstructural gene, NS1, promotes infection and viral maturation by suppressing the host immune system. Our goal is to explore cellular targets of NS1 and determine how they are affected during infection. In addition, since current treatments | Health and Human Services, Department of / National Institutes of Health | 6/03/2009 |
| UNIVERSITY OF CHICAGO, THE | $59,402 | Grant | Trans-NIH Recovery Act Research Support: Allogeneic stem cell transplantation is a life saving procedure for a variety of hematologic malignancies. Unfortunately, long term survival is significantly impacted by the development of invasive fungal infections. The risk of developing an invasive fun | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| WHITEHEAD INSTITUTE FOR BIO-MEDICAL RESEARCH | $15,582 | Grant | Trans-NIH Recovery Act Research Support: Herpesvirues are a significant cause of disease in the human population. Following initial acute infection, herpesvirueses establish latency and the viral DNA is maintained in cells. Murine gammaherpesvirus-68 (MHV-68) is used as a model to study the hu | Health and Human Services, Department of / National Institutes of Health | 6/18/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $34,121 | Grant | Trans-NIH Recovery Act Research Support: RNA silencing is an innate antiviral defense mechanism in plants that works primarily to decrease expression of viral proteins through RNA degradation. In an effort to overcome RNA silencing, plant viruses encode RNA silencing suppressor proteins. In rece | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF TEXAS AT AUSTIN | $105,520 | Grant | Trans-NIH Recovery Act Research Support: The biochemistry employed by bacteria differs markedly in many ways from that employed by humans. The enzyme Desll is an example that catalyzes an apparently radical-mediated deamination of TDP-4-amino- 4,6-dideoxy-glucose. Desll employs S-adenosylmethion | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| CEDARS-SINAI MEDICAL CENTER | $500,000 | Grant | Trans-NIH Recovery Act Research Support: This application requests $500,000.00 for facility Improvements for the Cedars-Sinai Medical Center Research Institute's (CSMCRI) Research Animal Facility in the Barbara and Marvin Davis Research Building (BMDRB). Specifically the funds requested will be | Health and Human Services, Department of / National Institutes of Health | 6/08/2009 |
| UNIVERSITY OF PITTSBURGH THE | $2,815,428 | Grant | Trans-NIH Recovery Act Research Support: Our overarching hypothesis is that liver non-parenchymal, antigen-presenting cells (APC) serve as key regulators of hepatic-based inflammatory/immune responses. This Program Project brings together the collective expertise of a highly-experienced and inte | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $3,982,810 | Grant | Trans-NIH Recovery Act Research Support: This study integrates three research programs and unique sources of female genital specimens to investigate the mucosal and systemic immune processes that impact the acquisition and progression of HIV-1 infection in women. | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| SCHEPENS EYE RESEARCH INSTITUTE, INC., THE | $1,315,913 | Grant | Trans-NIH Recovery Act Research Support: This project addresses one of the leading public health issues in the US - the spread of antibiotic resistant Staphylococcus aureus. S. aureus and especially methicillin resistant (MRSA) strains have emerged as leading causes of life-threatening infection | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF FLORIDA | $2,298,355 | Grant | Trans-NIH Recovery Act Research Support: The long-range goal of this Program Project is to develop therapeutic strategies that ameliorate muscle atrophy and augment muscle rehabilitation following pathological conditions such as spinal cord injury. Muscle atrophy or loss of muscle mass is a per | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| NATIONAL JEWISH HEALTH | $1,352,937 | Grant | Trans-NIH Recovery Act Research Support: The overall purpose of the project funded by this award is to support the early independent phase of the career of a pulmonary physician-scientist at National Jewish Health. National Jewish Health is the world's only institution that is dedicated to the | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| LOYOLA UNIVERSITY | $702,729 | Grant | Trans-NIH Recovery Act Research Support: Congestive heart failure (CHF) is associated with an abnormality in cardiac cell function. The molecular mechanisms that underlie this depressed function in CHF are not completely understood. The Major research theme at the Department of Cell and Molecula | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| WAYNE STATE UNIVERSITY (INC) | $625,397 | Grant | Trans-NIH Recovery Act Research Support: This proposal will create a synergy between a researcher transitioning to independent tenure-track faculty status and a division focused on reducing pediactric health disparities (CORE CENTER) to move the health disparities field fon/vard in the area of t | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $1,494,393 | Grant | Trans-NIH Recovery Act Research Support: In the NIMH Council Work Group Report on Transformational Neuroscience and Mental Illness (www.nih.nimh.gov - 2008 - co-chaired by Pat Levitt), it was noted that the scope of the research agenda to discover disease etiologies was vast-from individual gene | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| COLD SPRING HARBOR LABORATORY | $1,257,683 | Grant | Trans-NIH Recovery Act Research Support: Cold Spring Harbor Laboratory (CSHL) is seeking support to recruit a developmental neurobiologist with knowledge and expertise in neural circuit development and plasticity to significantly enhance current efforts to understand how neuropsychiatric disorde | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| CASE WESTERN RESERVE UNIVERSITY | $1,158,610 | Grant | Trans-NIH Recovery Act Research Support: This application proposes establishment of an interdisciplinary biomedical core focused on quality of life research for seriously ill people, including those who are at the end of life. The proposed biomedical core center, Building End-of-Life Science thr | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $990,602 | Grant | Trans-NIH Recovery Act Research Support: This proposal seeks support for hiring a young husband and ife team from the HHMI Janelia Farm Research Campus who will add great strength to the Vollum Institute. Drs. Haining Zhong and Tianyi Mao utilize newly developed optical approaches to solve probl | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF MIAMI | $1,278,043 | Grant | Trans-NIH Recovery Act Research Support: PREVENTING DRUG ABUSE AND HIV HISPANIC FIRST OFFENDORS - Hispanic youth in the juvenile justice system are at increased risk of HIV infection and of using illicit drugs. The proposed study's overarching goal is to reduce the ethnic disparities in illicit | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF TEXAS M D ANDERSON | $693,163 | Grant | Trans-NIH Recovery Act Research Support: Obesity has increased dramatically over the past 30 years in the USA and has been associated with pancreatitis and pancreatic cancer, as well as other cancers. A potential mechanistic link between obesity and cancer susceptibility is insulin-like growth f | Health and Human Services, Department of / National Institutes of Health | 5/07/2009 |
| UNIVERSITY OF WASHINGTON | $1,155,100 | Grant | Trans-NIH Recovery Act Research Support: Recent and ongoing clinical trials have demonstrated that advanced melanoma can be treated with a combination of nonmyeloablative chemotherapy and autologous adoptive T cell immunotherapy (AIT) to achieve a 50% clinical response rate. Such clinical respo | Health and Human Services, Department of / National Institutes of Health | 5/15/2009 |
| UNIVERSITY OF TOLEDO, THE | $749,000 | Grant | Trans-NIH Recovery Act Research Support: About one third of adults in the United States are diagnosed with fatty liver disease. About 10% will proceed to develop nonalcoholic steatohepatitis (NASH), and associated co-morbidities. Thus, it is imperative to understand the pathophysiology of the di | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF ARIZONA | $653,688 | Grant | Trans-NIH Recovery Act Research Support: This research proposal addresses consistent color and consistent grayscale presentation for digital color displays used in medical image interpretation. Currently, radiographic images such as chest, bone, and mammography are usually not viewed on color mo | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| CLAREMONT MCKENNA COLLEGE | $191,867 | Grant | Trans-NIH Recovery Act Research Support: In early 2007, Jeremy Sanders's group at the University of Cambridge reported the serendipitous discovery of a unique class of self-assembling, helical, organic nanotubes. Naphthalene diimide (NDI) derivatives, in which the aromatic core is flanked by two | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| HOBART AND WILLIAM SMITH COLLEGES | $215,100 | Grant | Trans-NIH Recovery Act Research Support: Academic Research Enhancement Award entitled 'Olfactory development in moths: a novel system for studying pattern formation, cell fate specification and neurogenesis during antennal formation' to identify the key insights into the biological mechanisms th | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| SOUTHERN ILLINOIS UNIVERSITY | $218,250 | Grant | Trans-NIH Recovery Act Research Support: Neural tube defects (such as anencephaly and Spina bifida) result from the embryonic failure of the neural tube to close followed by the outward expansion of the neural tissue. It is estimated that neural tube defects occur in 1 in 1,000 births in humans | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| BROWN UNIVERSITY IN PROVIDENCE IN STATE OF RI AND PROVIDENCE PLANTATIONS | $161,666 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Randomized cancer screening trials are considered the best approach for evaluating new cancer screening technologies. Unfortunately, these trials may underestimate the efficacy of a new screening technique if study par | Health and Human Services, Department of / National Institutes of Health | 5/28/2009 |
| NATIONAL ASSOCIATION OF COUNTY AND CITY HEALTH OFFICIALS | $113,600 | Grant | Trans-NIH Recovery Act Research Support: The specific aim of the proposed study is to develop GIS boundary shape files and assign standard FIPS codes for jurisdictions served by local health departments (LHDs) in the U.S. The shape files and FIPS codes will be attached to data on LHDs? infrastr | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $151,000 | Grant | Trans-NIH Recovery Act Research Support: Decreasing the number of children that develop cancer is hampered by a lack of clear understanding of its causes. To achieve the long-term objective of reducing the number of children who develop malignancy, it is first necessary to define causes. Evidenc | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $236,972 | Grant | Trans-NIH Recovery Act Research Support: Fibromyalgia is a debilitating chronic pain disorder that affects 2% of the population. Many drugs used to treat fibromyalgia are highly addictive, have limited clinical efficacy, and do not treat the cognitive symptoms of fibromyalgia. The long-range goa | Health and Human Services, Department of / National Institutes of Health | 6/19/2009 |
| KENT STATE UNIVERSITY | $221,176 | Grant | Trans-NIH Recovery Act Research Support: Three-dimensional shape and volume can be sensitive indicators of the physiological state of the cell, and are being extensively studied by biologists from very diverse fields. There are numerous publications relating cell shape to morphogenesis, cancer, | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| CORPORATION OF MERCER UNIVERSITY, THE | $226,815 | Grant | Trans-NIH Recovery Act Research Support: Human health is dependent upon the stability of the nuclear and mitochondrial genomes of each cell. Mitochondria generate energy through oxidative phosphorylation (OXPHOS), but this process also produces reactive oxygen species (ROS) that damage the intr | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| BETH ISRAEL DEACONESS MEDICAL CENTER INC | $1,000,000 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (03) Biomarker Discovery and Validation and specific Challenge Topic, 03-CA-103 Reagents for rapid screening of human tumor cells for defects in DNA repair and/or replication. Defective DNA repair is common | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| KAISER FOUNDATION HOSPITALS | $997,453 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (05) entitled 'Comparative Effectiveness Research (CER)'. Within that area, we are addressing the specific high priority challenge topic 05-CA-104* Comparative Effectiveness Research on Cancer Treatment. Our | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| LOMA LINDA VETERANS ASSOCIATION FOR RESEARCH AND EDUCATION | $154,000 | Grant | Trans-NIH Recovery Act Research Support: The overall purpose of this grant is to understand how exercise maintains bone health as well as the effect of exercise on bone formation regulators. Since IGF-I is an important regulator of bone formation, it is important to understand the role of IGF-I | Health and Human Services, Department of / National Institutes of Health | 8/07/2009 |
| NORTHSHORE UNIVERSITY HEALTHSYSTEM RESEARCH INSTITUTE | $1,146,615 | Grant | Trans-NIH Recovery Act Research Support: Our longitudinal study of a mouse model of Alzheimer's Disease incorporates microstructural MRI, behavior, morphometric and biochemical measures. The research will examine how cellular arrangement of hippocampus and behavior are affected by developing am | Health and Human Services, Department of / National Institutes of Health | 7/21/2009 |
| UNIVERSITY OF MARYLAND | $1,156,662 | Grant | Trans-NIH Recovery Act Research Support: The long term objectives of this research are to identify the mechanisms of neuromechanical (NM) impairments underlying postural balance dysfunction in older people, and to establish a scientifically grounded therapeutic program for enhancing balance func | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| VIRGINIA COMMONWEALTH UNIVERSITY | $595,758 | Grant | Trans-NIH Recovery Act Research Support: We will examine the novel contributions of Pfrx and Excl to aging in flies. Additionally, we will investigate several additional loci that are logically connected to these genes for a role in aging. Furthermore, we will begin to place the function of Excl | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $785,000 | Grant | Trans-NIH Recovery Act Research Support: Public narrative statement: the aim of this project is to understand pathogenic mechanisms responsible for Alzheimer's disease - an incurable disorder that affects large portion of the aging population | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| PURDUE UNIVERSITY | $525,829 | Grant | Trans-NIH Recovery Act Research Support: The study of adult health is being transformed by an emerging body of research linking early- life events and experiences with outcomes in adulthood and later life. The overall aim of this research is to build upon epidemiologic models of the life course | Health and Human Services, Department of / National Institutes of Health | 7/21/2009 |
| BANNER RESEARCH INSTITUTE (THE CORPORATION). | $1,707,871 | Grant | Trans-NIH Recovery Act Research Support: Considering the large and increasing number of Alzheimer's disease (AD) cases and the devastating course of the disease, there is a great need for developing drugs that target critical pathologic mechanisms in AD. Continuing research has revealed addition | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| TUFTS MEDICAL CENTER, INC. | $644,000 | Grant | Trans-NIH Recovery Act Research Support: The Borrelia burgdorferi infectious cycle requires the organism to survive in both tick and mammalian hosts. Previous studies have shown that B. burgdorferi accomplishes the adjustment to the vast differences in environmental challenges presented by these | Health and Human Services, Department of / National Institutes of Health | 5/11/2009 |
| THE VANDERBILT UNIVERSITY | $775,000 | Grant | Trans-NIH Recovery Act Research Support: Antigen receptor gene assembly by T and B lymphocytes is a fundamental aspect of adaptive immunity and is required to generate a diverse repertoire of immunoglobulins and T cell receptors, which recognize virtually any pathogen a species may encounter. Th | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY | $1,527,772 | Grant | Trans-NIH Recovery Act Research Support: Paramyxoviruses cause important human illnesses that contribute significantly to global disease and mortality. Two zoonotic paramyxoviruses, Hendra (HeV) and Nipah (NiV), are of urgent concern due to their lethal and transmissible nature. HeV and NiV in | Health and Human Services, Department of / National Institutes of Health | 9/27/2009 |
| ALLEGHENY-SINGER RESEARCH INSTITUTE | $1,278,754 | Grant | Trans-NIH Recovery Act Research Support: Streptococcus pneumoniae has remained one of the major causative agents of potentially life threatening human disease in our era. Nevertheless, introduction of antibiotics (penicillin) and - more recently - the conjugate vaccine provoked major evolutionar | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| WASHINGTON UNIVERSITY, THE | $758,602 | Grant | Trans-NIH Recovery Act Research Support: Toxoplasma gondii is a widespread protozoan parasite of wild, domestic, and companion animals that also commonly infects humans. Severe infections are normally only found in immunocompromised patients, including HIV infection, cancer chemotherapy, organ t | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| WISTAR INSTITUTE OF ANATOMY & BIOLOGY | $1,558,403 | Grant | Trans-NIH Recovery Act Research Support: The effect of innate cellular activation on HIV transmission efficiency, absent inflammation of the genital mucosa associated with active co-infections, remains unknown. Although some early attempts at answering this question have been tried, recent resul | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| UNIVERSITY OF WASHINGTON | $728,032 | Grant | Trans-NIH Recovery Act Research Support: Influenza is both a major public health threat and a NIAID bio defense category C priority pathogen. About 36,000 people die every year in the United States alone due to infection with commonly circulating influenza A viruses. Nearly 90% of these deaths a | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $1,185,662 | Grant | Trans-NIH Recovery Act Research Support: This project is being supported with funds from the American Recovery and Reinvestment Act, which may involve a reduction in the research aims and scope. If necessary, a revised abstract will be posted soon and this notice removed. DESCRIPTION (provided | Health and Human Services, Department of / National Institutes of Health | 6/29/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $639,666 | Grant | Trans-NIH Recovery Act Research Support: In this proposal we will characterize a novel signaling pathway activated by the growth factor heregulin (HRG) that involves the small G protein Rac1 and its activator P Rex1. Rac1 and P Rex1 mediate mitogenic and motile signals induced by HRG. The goal i | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| BETH ISRAEL DEACONESS MEDICAL CENTER INC | $735,360 | Grant | Trans-NIH Recovery Act Research Support: Thrombospondin-1 (TSP-1) regulates endothelial cell phenotype during the tissue remodeling that is associated with angiogenesis, wound healing and neoplasia. The importance of suppression of angiogenesis by TSP-1 is underscored by the observation that TSP | Health and Human Services, Department of / National Institutes of Health | 6/17/2009 |
| UNIVERSITY OF ROCHESTER | $637,025 | Grant | Trans-NIH Recovery Act Research Support: Epigenetic dysregulation and genetic mutations both contribute to cancer development. While genetic mutations such as gain-of-function mutations in oncogenes and loss-of-function mutations in tumor suppressors have been extensively studied, the mechanisms | Health and Human Services, Department of / National Institutes of Health | 5/05/2009 |
| UNIVERSITY OF PITTSBURGH THE | $623,500 | Grant | Trans-NIH Recovery Act Research Support: Cross-regulation of apoptosis and autophagy as a molecular basis for reversal of tumor TRAIL resistance. Defects in apoptotic capability that evolve during tumorigenesis promote tumor growth, provide survival advantage, and confound treatment. Such defec | Health and Human Services, Department of / National Institutes of Health | 5/05/2009 |
| UNIVERSITY OF NEW MEXICO | $2,421,152 | Grant | Trans-NIH Recovery Act Research Support: In the twenty-first century, cervical cancer prevention programs represent the expenditure of significant public health dollars. In anticipation of changes in cervical cancer prevention strategies such as first- and second- generation human papillomavirus | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF TEXAS M D ANDERSON | $639,100 | Grant | Trans-NIH Recovery Act Research Support: Persistence of dormant cancer cells that have resisted chemotherapy is a major barrier to curing ovarian cancer. Our group has developed the first inducible model for tumor dormancy in ovarian cancer using human ovarian cancer xenografts and has discovere | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $634,777 | Grant | Trans-NIH Recovery Act Research Support: Among American women breast cancer is the most common cancer and the 2nd leading cause of death from cancer. Breast density, which is defined as the ratio of fibroglandular tissue to the total fibroglandular and adipose tissue, is an important risk facto | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $1,075,349 | Grant | Trans-NIH Recovery Act Research Support: The treatment of oncogenic lesions residing in bone has advanced with an ever increasing array of therapies; however, response to treatment is considered unmeasurable according to existing clinical response criteria (RECIST). Therefore, the biomarkers ava | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| UNIVERSITY OF UTAH, THE | $752,500 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Methamphetamine (MA) dependence is a highly disabling and refractory condition, which results in serious impairment in social and occupational functioning. Although the endemic of MA use appears to have stabilized, MA | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| THE VANDERBILT UNIVERSITY | $1,325,683 | Grant | Trans-NIH Recovery Act Research Support: The overarching goal of this proposal is to develop, validate and disseminate a set of generalizable methods for non-invasive mapping of the spatio-temporal dynamics of functional and structural plastic changes in the primate CNS using MRI. It outlines a | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| SALK INSTITUTE FOR BLOGICAL STUDIES | $671,613 | Grant | Trans-NIH Recovery Act Research Support: Sign language provides a means to understand the sensory-motor influences on the neural organization of language. The goals of the present proposal are to uncover the neural basis of sign language using modern lesion-deficit mapping. This will not only an | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| OKLAHOMA MEDICAL RESEARCH FOUNDATION | $489,000 | Grant | Trans-NIH Recovery Act Research Support: Primary Sjogren's syndrome (pSS) is a chronic, inflammatory autoimmune disorder characterized by lymphocytic infiltration into exocrine glands. Hallmark features include salivary and lacrimal gland dysfunction, causing significant morbidity. pSS patients | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $752,063 | Grant | Trans-NIH Recovery Act Research Support: The goal of this research is to characterize expression and assembly of Treponema denticola (Td) surface proteins that mediate interactions with host tissue, thereby gaining insight into mechanisms of periodontal disease. We focus on analysis of two Td pr | Health and Human Services, Department of / National Institutes of Health | 5/05/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $942,000 | Grant | Trans-NIH Recovery Act Research Support: A. Specific Aims* Periodontal disease is a well-characterized chronic inflammatory bone destructive disease induced by bacterial infection with the Gram-negative pathogen Porphyromonas gingivalis. The cellular composition of inflammatory bone lesions in h | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $804,823 | Grant | Trans-NIH Recovery Act Research Support: Histone modifications provide a mechanism for regulating the diverse structural and functional features of chromatin, including control of gene regulation and maintenance of genomic integrity. Histone modifications play important roles in cell growth and | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| MAYO CLINIC | $752,195 | Grant | Trans-NIH Recovery Act Research Support: Irritable bowel syndrome (IBS) affects about 15% of the U.S. population. Despite increasing understanding of the pathophysiology of IBS, there are unmet clinical needs and no effective medication approved for the treatment of abdominal pain associated wit | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE/CWRU | $1,142,609 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Nonalcoholic fatty liver disease (NAFLD) in humans has become an increasing public health problem paralleling the increase in obesity, type II diabetes, and changing dietary and activity patterns. The spectrum of NAFLD | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| THE VANDERBILT UNIVERSITY | $697,500 | Grant | Trans-NIH Recovery Act Research Support: The imbalance in glucose homeostasis in diabetic patients is caused by loss or dysfunction of insulin secreting pancreatic islet ? cells. A concerted effort is being made to understand the molecular programs underlying ? cell formation and function to pr | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| NORTHERN ARIZONA UNIVERSITY | $1,356,113 | Grant | Trans-NIH Recovery Act Research Support: In 1995 we conducted a cross-sectional study to identify the effects of traditional and western environments on prevalence of type 2 diabetes mellitus (T2DM) and obesity in Pima Indians in Mexico and the United States (1-8). The Mexican Pimas live in a re | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $691,831 | Grant | Trans-NIH Recovery Act Research Support: Congenital obstructive nephropathy is the most important identifiable cause of renal impairment in infants and children. Despite this, indications for surgical intervention are controversial, and renal recovery is often disappointing. While mechanisms res | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $1,640,420 | Grant | Trans-NIH Recovery Act Research Support: Identification of Genes Causing Familial Crohn?s Disease. Nearly 500,000 Americans, both children and adults, have Crohn?s disease, and in approximately one-quarter of those affected, two or more family members have the disease. People of Jewish ancestry | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| WASHINGTON UNIVERSITY, THE | $760,000 | Grant | Trans-NIH Recovery Act Research Support: Diagnosis and treatment of various pathologic conditions can be achieved by integrating multimodal imaging systems that furnish complementary information to improve patient management. The availability of high-resolution tomography systems, fast computers | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $1,061,981 | Grant | Trans-NIH Recovery Act Research Support: Hierarchical Modeling of Interactions in Genome-Wide and Pathway-Based Association Studies: The overarching goal of this grant is to investigate the use of hierarchical modeling in the study of gene-environment and gene-gene interactions in both genome-wi | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF LOUISVILLE | $740,000 | Grant | Trans-NIH Recovery Act Research Support: 'Atherosclerosis is the leading cause of morbidity and mortality in industrialized nations. Studies are in progress to evaluate the expression of L1 during the course of atherosclerotic disease progression in the Apoetm1Unc mouse model and will elucidate | Health and Human Services, Department of / National Institutes of Health | 9/26/2009 |