Listing all stimulus spending by amount, in descending order. Return to National Institutes of Health page
Amount refers to both the amount of stimulus funding going toward the project and the face value of the loan.
| Recipient | Amount | Type | Description | Federal Dept./Agency | Date |
|---|---|---|---|---|---|
| UNIVERSITY OF WISCONSIN SYSTEM | $99,458 | Grant | Trans-NIH Recovery Act Research Support: The gene Sonic hedgehog (Shh) encodes a secreted signaling peptide that acts as a potent inducer of growth during fetal development. The role of Hedgehog (Hh) signaling in prostate development and prostate growth regulation is the major focus of research | Health and Human Services, Department of / National Institutes of Health | 11/23/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $98,600 | Grant | Trans-NIH Recovery Act Research Support: These supplemental funds will be used to pursue an Axio Observer fluorescence microscope that will be heavily used by all members of our laboratory and will markedly stimulate the efficiency of our research program. Immunofluorescence microscopy is a powe | Health and Human Services, Department of / National Institutes of Health | 12/14/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $99,008 | Grant | Trans-NIH Recovery Act Research Support: The overall hypothesis presented in this grant provides an integrated pathophysiological schema whereby caspase-1 and caspase-1-related cytokines like IL-18 and IL-1a lead to increased macrophage and NK cell infiltration in the kidney and resultant ischem | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE | $73,618 | Grant | Trans-NIH Recovery Act Research Support: The molecular basis of terminal nephron differentiation, the process by which immature renal epithelial cells exit the cell cycle and express physiological functions, remains obscure. Failure of terminal nephron differentiation results in renal dysplasia, | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF CALIFORNIA, SANTA BARBARA | $106,927 | Grant | Trans-NIH Recovery Act Research Support: This Administrative Supplement is aimed at significantly accelerating the pace of our research for the Specific Aims 2 and 3 as detailed in the original proposal of the parent grant. The goal of these Aims is to investigate the role of STAT6 and the cleav | Health and Human Services, Department of / National Institutes of Health | 12/21/2009 |
| THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The goal of this proposal is to understand the role of class IA phosphatidylinositol 3-kinase (PI3K) p110a and p110? in regulating pathological and physiological cell growth in the pancreas and skeletal muscle. These two class IA PI3Ks are postulated to c | Health and Human Services, Department of / National Institutes of Health | 12/28/2009 |
| DUKE UNIVERSITY | $98,550 | Grant | Trans-NIH Recovery Act Research Support: In this proposal we propose to extend our prior observations that stromal cell lines can influence the outcome of HSC fate by controlling the ratio of asymmetric and symmetric division, and test whether primary bone marrow stromal cells also influence asy | Health and Human Services, Department of / National Institutes of Health | 11/18/2009 |
| UNIVERSITY OF NORTH CAROLINA AT GREENSBORO | $138,994 | Grant | Trans-NIH Recovery Act Research Support: NIDDK Administrative Supplement to DK063070: Determine the Role of CaMKII, JNK, and PLC in 10,12 CLA-mediated inflammation, insulin resistance, and delipidation in human adipocytes. Award #3R01DK063070-07S2. This Administrative Supplement was requested | Health and Human Services, Department of / National Institutes of Health | 12/17/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $13,445 | Grant | Trans-NIH Recovery Act Research Support: This project seeks to a) quantify the nature and sources of diabetic alveolar function at rest and during exercise, b) relate changes in alveolar function to extra-pulmonary microangiopathy, and c) establish long term cohorts to examine the natural progre | Health and Human Services, Department of / National Institutes of Health | 12/23/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $49,999 | Grant | Trans-NIH Recovery Act Research Support: Disorders of renal phosphate wasting are the most common forms of rickets and osteomalacia in Western countries. Our work and that of others has established that the hormone Fibroblast growth factor-23 (FGF23) is a critical mediator of phosphate and vitam | Health and Human Services, Department of / National Institutes of Health | 12/08/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $99,999 | Grant | Trans-NIH Recovery Act Research Support: Obesity, insulin resistance, fatty liver disease, and type 2 diabetes frequently cluster together and are among the most common chronic metabolic diseases threatening human welfare in the US and around the world. Our work in the past has demonstrated that | Health and Human Services, Department of / National Institutes of Health | 12/14/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $36,473 | Grant | Trans-NIH Recovery Act Research Support: The supplement funds the purchase of a piece of equipment. We are in the process of obtaining quotes for this and expect to initiate purchasing procedures within 1 week. | Health and Human Services, Department of / National Institutes of Health | 12/03/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $100,000 | Grant | Trans-NIH Recovery Act Research Support: Apical; Appearance; Assay; Bile Canaliculi; Bioassay; Biologic Assays; Biological Assay; C elegans; C.elegans; Caenorhabditis elegans; Cell Communication and Signaling; Cell Locomotion; Cell Migration; Cell Movement; Cell Polarity; Cell Signaling; Cell me | Health and Human Services, Department of / National Institutes of Health | 11/10/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $30,780 | Grant | Trans-NIH Recovery Act Research Support: Targeted Genetic Analysis of T2D and Quantitative Traits-ARRA. The purpose of this administrative supplement is to accelerate the tempo of laboratory studies to test the functional roles of putative type 2 diabetes susceptibility variants by purchasing n | Health and Human Services, Department of / National Institutes of Health | 12/28/2009 |
| UNIVERSITY OF MARYLAND | $119,372 | Grant | Trans-NIH Recovery Act Research Support: Hematopoiesis is the development and formation of all blood cell types. All peripheral blood cells are derived from pluripotential stem cells. These cells are capable of both self-renewal and sequential commitment to the diverse blood cell lineages. The p | Health and Human Services, Department of / National Institutes of Health | 11/18/2009 |
| LOUISIANA STATE UNIVERSITY SYSTEM | $96,502 | Grant | Trans-NIH Recovery Act Research Support: This application is highly responsive to three program announcements of the NIH: PAR-06-457 (Translational Research in Diabetes), PA-01-114 (Chromium as Adjuvant Therapy in Diabetes), and PA-01- 071 (Metals in Medicine). Type-1 diabetes is associated with | Health and Human Services, Department of / National Institutes of Health | 12/21/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO ,THE | $29,875 | Grant | Trans-NIH Recovery Act Research Support: Given their small size, high fertility and short life span, common marmosets are an efficient nonhuman primate model in which to examine the effects of early life environment on adult disease outcomes. The primary goal of the proposed research is to deter | Health and Human Services, Department of / National Institutes of Health | 12/09/2009 |
| UNIVERSITY OF PITTSBURGH THE | $99,940 | Grant | Trans-NIH Recovery Act Research Support: Addition of a post-doctoral fellow to expedite research in specific areas of the proposal: Based on our preliminary findings (see below) that PTHrP improves beta cell survival against cytokine-mediated cell death (SA1) and that PTH1R KO mice have an impai | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| BAYLOR COLLEGE OF MEDICINE | $159,817 | Grant | Trans-NIH Recovery Act Research Support: A major problem currently facing pediatric urology involves the diagnosis of disorders in genital and urinary tract development. Alththough much of the current diagnosis is descriptive (i.e. cyptorchidism: a failure of the testis to descend),the molecula | Health and Human Services, Department of / National Institutes of Health | 11/28/2009 |
| MAGEE-WOMENS HEALTH CORPORATION | $41,405 | Grant | Trans-NIH Recovery Act Research Support: Adipose tissue development is a crucial contributor to obesity and the associated type II diabetes and Metabolic Syndrome. Much has been learned about adipogenesis in tissue culture models, but relatively little is known about its in vivo mechanisms. Our | Health and Human Services, Department of / National Institutes of Health | 12/14/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $92,636 | Grant | Trans-NIH Recovery Act Research Support: We are requesting an administrative supplement (NOT OD 09 056) under the Recovery Act to add a full time research coordinator to our staff. The additional research position will provide an immediate economic benefit to the region by generating another fu | Health and Human Services, Department of / National Institutes of Health | 12/15/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $99,205 | Grant | Trans-NIH Recovery Act Research Support: Congenital malformations of the urinary tract account for 40-50% of pediatric end-stage kidney failure worldwide. We previously demonstrated that familial forms of urinary tract malformations are genetically heterogenous and we have localized susceptibili | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $66,000 | Grant | Trans-NIH Recovery Act Research Support: REGULATION OF INSULIN SECRETION AND LIFESPAN The goal of this project is to identify factors that regulate secretion of neuropeptides generally, with a specific focus on insulin-like growth factors. The motivation for this project is two-fold. First, insu | Health and Human Services, Department of / National Institutes of Health | 12/28/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE | $264,999 | Grant | Trans-NIH Recovery Act Research Support: Hyperthyroidism affects one in 1000 American women and is accompanied by osteoporosis and a high fracture risk. We showed that decrements in the pituitary hormone TSH accompany the high thyroid hormone levels, both of which contribute to the bone loss. Th | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $58,000 | Grant | Trans-NIH Recovery Act Research Support: This award is for a piece of equipment, a plate reader to be used for a range of analytical assays in the laboratory. | Health and Human Services, Department of / National Institutes of Health | 1/01/2010 |
| DUKE UNIVERSITY | $230,669 | Grant | Trans-NIH Recovery Act Research Support: Application in response to Notice Number: NOT-OD-09-058 Notice Title: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. Our laboratory has focused on discovering genes that are important for regulating iron homeos | Health and Human Services, Department of / National Institutes of Health | 11/17/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $123,240 | Grant | Trans-NIH Recovery Act Research Support: This application is in response to NOT-OD-09-058, NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. Studies supported by the parent grant address fundamental questions concerning how iron homeostasis is regulated | Health and Human Services, Department of / National Institutes of Health | 11/10/2009 |
| UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC. | $62,000 | Grant | Trans-NIH Recovery Act Research Support: Fatty acid metabolism plays important roles in glucose homeostasis, glucose-stimulated insulin secretion and lipotoxicity in islet beta-cells. Defect in fatty acid desaturation leads to beta-cell loss and also lipoatrophy in our diabetes mouse model. This | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| UNIVERSITY OF KENTUCKY | $37,680 | Grant | Trans-NIH Recovery Act Research Support: Normal regulation of insulin gene transcription by glucose is essential for the maintenance of glucose homeostasis, and requires the beta-cell specific transcription factors Pdx-1, MafA and NeuroD1. However the exact mechanism(s) by which glucose increase | Health and Human Services, Department of / National Institutes of Health | 12/07/2009 |
| UNIVERSITY OF PITTSBURGH THE | $30,000 | Grant | Trans-NIH Recovery Act Research Support: Funds for the purchase of equipment, as a supplement to Chaperone Actions in CFTR Biogenesis (3R01DK068196-06), will be used to purchase a fluorescence spectrophotometer. This equipment will be used to facilitate the completion of in vitro structural stu | Health and Human Services, Department of / National Institutes of Health | 12/28/2009 |
| UNIVERSITY OF CHICAGO, THE | $99,959 | Grant | Trans-NIH Recovery Act Research Support: The parent grant aims to define the mechanisms by which the proinflammatory cytokines interferon-y (IFN'y) and tumor necrosis factor (TNF) disrupt the intestinal epithelial barrier and trigger disease. The specific aims of the parent grant were: 1. To de | Health and Human Services, Department of / National Institutes of Health | 12/03/2009 |
| UNIVERSITY OF UTAH, THE | $99,959 | Grant | Trans-NIH Recovery Act Research Support: Urinary tract infections are among the most common of infectious diseases, representing a serious economic and medical burden worldwide. By delineating how uropathogenic bacteria colonize and persist within the host, we hope to facilitate the development | Health and Human Services, Department of / National Institutes of Health | 12/21/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $84,152 | Grant | Trans-NIH Recovery Act Research Support: Atypical antipsychotics are widely prescribed to millions of people in the United States for treatment of schizophrenia, bipolar disorder and other psychiatric conditions. Evidence has been accumulating that these drugs often cause substantial weight gain | Health and Human Services, Department of / National Institutes of Health | 1/01/2010 |
| NEW YORK MEDICAL COLLEGE | $100,001 | Grant | Trans-NIH Recovery Act Research Support: We proposed that as epoxyeicosatrienoic acids (EETs) are vasodilators and natriuretic and can account for the biological actions of adenosine acting on adenosine 2A receptor (A2A R), and that EETs and adenosine play a crucial role in the adaptive respons | Health and Human Services, Department of / National Institutes of Health | 12/08/2009 |
| UNIVERSITY OF CINCINNATI | $99,877 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Group 1B phospholipase A2 (PLA2g1B) is synthesized by both exocrine acinar cells and endocrine B-islet cells of the pancreas. It is generally thought to act only as a lipolytic enzyme, facilitating lipid digestion and | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| BETH ISRAEL DEACONESS MEDICAL CENTER INC | $80,700 | Grant | Trans-NIH Recovery Act Research Support: Obesity is a serious illness, with a complex etiology, which is associated with increased risk in the development of multiple other morbidities including Type II diabetes, cardiovascular disease, hypertension and some neoplasias. In the United States, rat | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $58,850 | Grant | Trans-NIH Recovery Act Research Support: From a combination of genetic analyses and RNAi screening, we have discovered hundreds of gene inactivations and mutations that promise to reveal the neuroendocrine circuit through which C. elegans fat storage set points are determined. Because RNAi does | Health and Human Services, Department of / National Institutes of Health | 12/21/2009 |
| CALIFORNIA INSTITUTE OF TECHNOLOGY | $100,934 | Grant | Trans-NIH Recovery Act Research Support: This supplement will facilitate completion of two important research projects that will add greatly to our understanding of fat storage, metabolism, and feeding in an insect model system, the fruit fly Drosophila. It is hoped that the use of the fly sys | Health and Human Services, Department of / National Institutes of Health | 11/18/2009 |
| UNIVERSITY OF TEXAS AT AUSTIN | $116,679 | Grant | Trans-NIH Recovery Act Research Support: The parent grant is 1 R01 DK070618-01A2, Control of Dynamically Coupled Cavitation Bubbles in Shock- Wave Lithotripsy (SWL), the start date for which was 15 April 2008 and the duration of which is 4 years. In that grant there are three Specific Aims: (1) | Health and Human Services, Department of / National Institutes of Health | 11/19/2009 |
| CHILDREN'S HOSPITAL CORPORATION, THE | $84,529 | Grant | Trans-NIH Recovery Act Research Support: The previous fifty years of study on the inductive events that surround early kidney development have focused on the two major cell types, the mesenchyme and epithelium. Recent work in other organs, such as liver and pancreas, have indicated a role for va | Health and Human Services, Department of / National Institutes of Health | 12/17/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $21,000 | Grant | Trans-NIH Recovery Act Research Support: Title: TGF-Beta and IGF in Mesenchymal Stem Cell Chondrogenesis 3R01DK070929-05S1 Project begin date: 12/01/2009 Project end date: 03/30/2010 This is to provide a final report on 3R01DK070929-05S1 an equipment ARRA grant which was used to speed and enhan | Health and Human Services, Department of / National Institutes of Health | 11/30/2009 |
| VIRGINIA COMMONWEALTH UNIVERSITY | $97,320 | Grant | Trans-NIH Recovery Act Research Support: The Fels Longitudinal Study (FLS) is the world's largest and oldest longitudinal study of human growth and body composition. The FLS continues to recruit 10-20 new subjects every year and collects serial data from participants who enrolled decades ago. Th | Health and Human Services, Department of / National Institutes of Health | 12/26/2009 |
| UNIVERSITY OF CHICAGO, THE | $104,590 | Grant | Trans-NIH Recovery Act Research Support: The present application requests an administrative supplement for a 2-year period for R01 DK-071696 Sleep disturbances as a non-traditional risk factor for chronic kidney disease (CKD). The parent grant is an ancillary study to the Chronic Renal Insuffici | Health and Human Services, Department of / National Institutes of Health | 11/28/2009 |
| ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE | $73,305 | Grant | Trans-NIH Recovery Act Research Support: Congenital abnormalities of the kidney and urinary tract (CAKUT) are the major cause of renal failure in childhood. In order to develop more effective preventive and therapeutic interventions, it is important to better understand the molecular pathogenesi | Health and Human Services, Department of / National Institutes of Health | 11/23/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $52,500 | Grant | Trans-NIH Recovery Act Research Support: Insulin resistance for glucose disposal by skeletal muscle is an essential and perhaps primary defect for Type 2 diabetes. The broad, long-term objective is to fully understand the mechanisms whereby insulin- and exercise intersect to co-regulate skeletal | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| MICHIGAN STATE UNIVERSITY | $79,792 | Grant | Trans-NIH Recovery Act Research Support: In this proposal, we describe the development of an analytical system that will enable the elucidation of the role of red blood cells (RBCs) in complications resulting from type II diabetes. Specifically, using a lab on a chip approach, we propose to exam | Health and Human Services, Department of / National Institutes of Health | 6/22/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $80,340 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of the parent grant (DK 071929) is to study the mechanisms involved in Hox patterning of the kidney. To increase the tempo of research and to take advantage of new opportunities created by our recent findings supported by the parent grant | Health and Human Services, Department of / National Institutes of Health | 12/21/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $46,444 | Grant | Trans-NIH Recovery Act Research Support: The University of Alabama at Birmingham (UAB) is Alabama's largest employer. Eight in every 100 jobs in the Birmingham area, and 2.8 jobs in every 100 jobs in Alabama, are related to UAB. UAB's overall economic impact in the Birmingham metro area exceeds | Health and Human Services, Department of / National Institutes of Health | 12/08/2009 |
| BENAROYA RESEARCH INSTITUTE AT VIRGINIA MASON | $64,969 | Grant | Trans-NIH Recovery Act Research Support: Induction of regulatory T cells requires T cell stimulation via the T cell receptor. Impairment in signaling via the TCR could lead to a diminished ability to induce T regulatory cells. Identifying whether defects in the generation of Tregs is present in | Health and Human Services, Department of / National Institutes of Health | 12/28/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $33,000 | Grant | Trans-NIH Recovery Act Research Support: Description of projects. Supplementary funds provided by the Recovery Act will be used to purchase new equipment currently unavailable in the laboratory and to hire a research assistant. As described below, this will accelerate progress on both of the Spe | Health and Human Services, Department of / National Institutes of Health | 12/03/2009 |
| WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY | $46,865 | Grant | Trans-NIH Recovery Act Research Support: We originally requested funds to assist our laboratory in measuring NAD and nicotinamide metabolites in a variety of biological samples and in order to screen chemical libraries in order to identify inhibitors and activators of sirtuins, NAD dependent de | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| UNIVERSITY OF LOUISVILLE | $100,000 | Grant | Trans-NIH Recovery Act Research Support: These studies wil provide strong evidence whether diabetes induced cardiomyocyte mitochondrial DNA damage is a major cause for the progression of diabetic cardiomyopathy. The most important goal of this proposal is to determine if overexpression of OGG pr | Health and Human Services, Department of / National Institutes of Health | 12/21/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $254,500 | Grant | Trans-NIH Recovery Act Research Support: Obesity is the primary risk factor for diabetes and multiple other metabolic diseases. During the development of obesity, energy intake exceeds energy expenditure, and the excess energy is stored as triglycerides in adipose tissue. Adipose tissue secret | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $100,000 | Grant | Trans-NIH Recovery Act Research Support: Mitochondrial Diabetes & Manganic Prophyrin Treatment - Supplement P.I. Douglas C. Wallace DK-73691 Award Description: This supplement grant will be used to purchase a Seahorse XF Extracellular Analyzer for high throughput screening of mitochondrial oxi | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| MAINE MEDICAL CENTER | $13,566 | Grant | Trans-NIH Recovery Act Research Support: Support for equipment replacement. 1) Purchase new CO2 incubator to replace incubator that is no longer functional. Specific Aims of Parent Grant Precise modulation of receptor tyrosine kinase (RTK) signaling is critical for normal skeletal development. | Health and Human Services, Department of / National Institutes of Health | 1/01/2009 |
| FLORIDA STATE UNIVERSITY, THE | $79,792 | Grant | Trans-NIH Recovery Act Research Support: Overall purpose: The main focus of my parent grant is to investigate the mechanism underlying estradiol's (E2's) anorexigenic (appetite suppressing) effect. This Administrative Supplement provides funds to purchase 16 custom rat cages and a freezing, slid | Health and Human Services, Department of / National Institutes of Health | 12/03/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $49,178 | Grant | Trans-NIH Recovery Act Research Support: The characterization of the phenotype of our genetically altered mouse models requires significant analyses at the molecular, histological, and biochemical level. We will purchase equipment to facilitate and accelerate our future analyses. For biochemical | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| UNIVERSITY OF LOUISVILLE | $90,112 | Grant | Trans-NIH Recovery Act Research Support: The supplemental funds awarded for this project will provide much needed equipment that will facilitate the histological process for the parent proposal. | Health and Human Services, Department of / National Institutes of Health | 12/21/2009 |
| MARQUETTE UNIVERSITY | $44,000 | Grant | Trans-NIH Recovery Act Research Support: This proposal investigates the influence of serotonin (5-HT) and its associated neurons in the hypothalamic paraventricular nuclei (PVN) on neuronal corticotropin releasing factor (CRF) mRNA expression and feeding behavior in rats. PVN CRF neurons are imp | Health and Human Services, Department of / National Institutes of Health | 12/16/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $96,192 | Grant | Trans-NIH Recovery Act Research Support: Osteoclasts are large, multinucleated cells that play a central role in bone resorption. They are derived from hematopoietic precursors in response to a number of regulatory factors, the most important of which is RANKL. RANKL is both necessary and suffi | Health and Human Services, Department of / National Institutes of Health | 11/27/2009 |
| UNIVERSITY OF MARYLAND | $40,000 | Grant | Trans-NIH Recovery Act Research Support: Ectopic fat deposition, which is the accumulation of lipid droplets outside the adipose tissue, is well recognized as a strong prognostic factor for the development of insulin resistance and 'metabolic syndrome' in obesity and people with lipodystrophies. | Health and Human Services, Department of / National Institutes of Health | 12/21/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $124,747 | Grant | Trans-NIH Recovery Act Research Support: The scope of the award is to examine the function of the nuclear receptor peroxisome proliferator-activated receptor delta in the liver and to test the hypothesis that this receptor regulates hepatic gene programs that promote glucose utilization for the | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| NEW YORK UNIVERSITY (INC) | $81,312 | Grant | Trans-NIH Recovery Act Research Support: This award is for a one time purchase of a chromotography machine that will improve the prospects of success in an existing project designed to discover chemical compounds that modulate cell stress signaling pathways and may, one day be used to treat a br | Health and Human Services, Department of / National Institutes of Health | 12/21/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $18,000 | Grant | Trans-NIH Recovery Act Research Support: Animal studies have shown that T1AM has profound metabolic effects, including lipid alterations, and we now know that T1AM is tightly bound to apo B-100 in humans. Given the known role of apo B-100 In hyperlipidemia and metabolic disease, we believe that | Health and Human Services, Department of / National Institutes of Health | 12/03/2009 |
| UNIVERSITY OF OREGON | $99,999 | Grant | Trans-NIH Recovery Act Research Support: Helicobacter pylori infections are associated with the majority of gastric cancers, which are the second leading cause of cancer deaths worldwide. The most carcinogenic strains of H. pylori strains are ones whose genomes encode a type IV secretion system | Health and Human Services, Department of / National Institutes of Health | 12/08/2009 |
| DUKE UNIVERSITY | $134,204 | Grant | Trans-NIH Recovery Act Research Support: Accumulating evidence suggests that podocyte depletion is a final common pathway causing progressive loss of kidney function characteristic of glomerular disease processes. In response to the Program Announcement (PA-07-012) entitled, Animal models of NID | Health and Human Services, Department of / National Institutes of Health | 12/07/2009 |
| UNIVERSITY OF MARYLAND | $79,100 | Grant | Trans-NIH Recovery Act Research Support: The relevance of bladder urothelial cells (BUG) to human disease has traditionally been understood only in terms of urothelial cell carcinoma. However, there is exciting new literature highlighting the role of altered BUG structure and function in non-neo | Health and Human Services, Department of / National Institutes of Health | 11/19/2009 |
| UNIVERISTY OF MISSISSIPPI MEDICAL CENTER | $100,414 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of the parent grant is to examine some of the mechanisms by which estrogens protect the kidney in the setting of diabetes through the following specific aims: 1. 17B-estradiol (E2) regualtes teh renal renin-angiotensin system (RAS), 2. E2 | Health and Human Services, Department of / National Institutes of Health | 12/20/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $62,500 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this grant is to assess how disruption of the cilium results in hyperphagia induced obesity. We proposed three aims in the parent proposal. The first is to analyze the obesity phenotype associated with cilia mutant mice. The goal of t | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $59,368 | Grant | Trans-NIH Recovery Act Research Support: Vascular complications are a significant cause of morbidity and mortality in ADPKD. Interestingly it has been observed that there is a subset of families with ADPKD who also exhibit features of the Marfan syndrome (MFS).Our studies demonstrate that mice, | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO ,THE | $98,960 | Grant | Trans-NIH Recovery Act Research Support: Adiponectin is an adipose tissue-derived hormone with anti-diabetic, anti-atherogenic, and anti-inflammatory functions. Circulating adiponectin exists as trimer, hexamer, and high molecular weight species which activate divergent signaling pathways and ex | Health and Human Services, Department of / National Institutes of Health | 12/14/2009 |
| BOSTON MEDICAL CENTER CORPORATION | $80,765 | Grant | Trans-NIH Recovery Act Research Support: The main goal of Parent and Supplemental Grant is to identify a novel function for SIRT1 to regulate AMPK signaling and control lipid biosynthesis and its implication in hepatic steatosis and hyperlipidemia in diabetes. During this quart of the ARRA award | Health and Human Services, Department of / National Institutes of Health | 12/28/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $94,450 | Grant | Trans-NIH Recovery Act Research Support: Kidney failure is a major cause of morbidity and mortality in the United States and worldwide. Transcriptional regulation of podocyte diseases is not as yet well understood. Our long term goal is to define the precise mechanisms of proteinuria and glomeru | Health and Human Services, Department of / National Institutes of Health | 11/27/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $80,913 | Grant | Trans-NIH Recovery Act Research Support: Acute kidney injury (AKI) is a tremendous burden on human health and health care resources. Acute alterations of the kidney microvasculature significantly contribute to kidney dysfunction during AKI. In addition, there is growing evidence that chronic alt | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| CHILDREN'S HOSPITAL CORPORATION, THE | $96,360 | Grant | Trans-NIH Recovery Act Research Support: Fibroproliferative remodeling in the urinary tract is associated with a number of pathologies including hypertrophic bladder growth secondary to outlet obstruction, neurogenic bladder and diabetes. Although the macroscopic changes that occur in the bladde | Health and Human Services, Department of / National Institutes of Health | 12/07/2009 |
| RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL | $49,157 | Grant | Trans-NIH Recovery Act Research Support: The overall aim if the supplement award is to determine the ability of inhibition of hsp25 phosphorylation to protect against and/or ameliorate podocyte injury. | Health and Human Services, Department of / National Institutes of Health | 12/08/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $20,930 | Grant | Trans-NIH Recovery Act Research Support: This supplement will allow the purchase of additional food intake monitoring cages for rats, to facilitate the aims of the project. | Health and Human Services, Department of / National Institutes of Health | 12/09/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE | $103,030 | Grant | Trans-NIH Recovery Act Research Support: The goal of this application for an administrative supplement is to enable our laboratory to retain a postdoctoral fellow and purchase equipment and supplies to accelerate the pace of the most clinically relevant and scientifically important research in m | Health and Human Services, Department of / National Institutes of Health | 11/23/2009 |
| BOSTON MEDICAL CENTER CORPORATION | $44,000 | Grant | Trans-NIH Recovery Act Research Support: This award supports the purchase of IncuCyte Plus Phase-contrast Imaging System to provide continuous, time-lapse images of human stem cells as they undergo myogenic differentiation in culture. The acquisition of this equipment will enhance the quality o | Health and Human Services, Department of / National Institutes of Health | 12/14/2009 |
| CHILDRENS HOSPITAL OF PHILADELPHIA | $144,616 | Grant | Trans-NIH Recovery Act Research Support: This is a competitive supplement in response to NOT-OD-09-058 (NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications). Diabetes is a metabolic disorder that currently affects over 180 million people worldwide. Common t | Health and Human Services, Department of / National Institutes of Health | 12/28/2009 |
| UNIVERSITY OF ROCHESTER | $70,800 | Grant | Trans-NIH Recovery Act Research Support: A reconditioned-?BNII nephelometer will be purchased and Cystatin C will be measured in sera of subjects in the NIH funded CKiD study. Cystatin C is an endogenous measure of kidney function. The BNII will also be used to measure Cystatin C in subjects of | Health and Human Services, Department of / National Institutes of Health | 12/31/2009 |
| COLORADO STATE UNIVERSITY | $99,600 | Grant | Trans-NIH Recovery Act Research Support: The primary goal of the original and newly proposed studies is to identify possible therapeutic targets for the prevention and treatment of obesity and/or anorexia. This proposal for an administrative supplement will expedite and expand upon the parent pr | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $200,000 | Grant | Trans-NIH Recovery Act Research Support: The overall objective of this proposal is to identify and characterize putative stem/progenitor cells in the adult pancreas. The identification of such cells would facilitate the development of a cell replacement therapy for patients with diabetes. Such t | Health and Human Services, Department of / National Institutes of Health | 12/07/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $77,001 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The pancreatic islet is a dynamic tissue which can increase insulin secretion in response to increased secretory demand. The adaptation is due to both increased intrisic islet secretory capacity and expansion of beta-c | Health and Human Services, Department of / National Institutes of Health | 12/03/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $94,120 | Grant | Trans-NIH Recovery Act Research Support: The past several decades have revealed a devasting trend- the dramatic increase in preventable diseases in children, including obesity, diabetes, cardiovascular disease and nonalcoholic fatty liver disease (NAFLD). The general hypothesis of this proposal | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $50,770 | Grant | Trans-NIH Recovery Act Research Support: Despite the large number of pregnant women and neonates infected with HIV receiving long-term treatment with antiretroviral agents, little is understood about the handling of these drugs in utero and in the neonatal kidney. Although the drugs are generall | Health and Human Services, Department of / National Institutes of Health | 12/07/2009 |
| CEDARS-SINAI MEDICAL CENTER | $68,231 | Grant | Trans-NIH Recovery Act Research Support: Administrative supplement is for additional computing equipment to facilitate analysis, as well as research equipment that will accelerate the ability to carry out the genotyping and sequencing proposed in the original grant. | Health and Human Services, Department of / National Institutes of Health | 12/26/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $45,504 | Grant | Trans-NIH Recovery Act Research Support: In our parent grant proposal, we proposed three aims to identify and characterize the role and mechanism of LCN2 in insulin resistance and metabolic regulation using LCN2 knockout mice. Aim 1 investigates the regulation of LCN2 in inflammation, insulin a | Health and Human Services, Department of / National Institutes of Health | 12/14/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $51,256 | Grant | Trans-NIH Recovery Act Research Support: Diabetes mellitus is characterized by the selective destruction of insulin-producing beta- cells, which leads to a deficiency in insulin secretion and as a result, to hyperglycemia. As islet transplantation becomes an acceptable clinical modality for rest | Health and Human Services, Department of / National Institutes of Health | 1/01/2010 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $99,442 | Grant | Trans-NIH Recovery Act Research Support: Project Narrative. Obesity and type 2 diabetes affect millions of people and are the cause of major health problems in the United States. To prevent and develop more effective treatments against these pathologies, a better understanding of the basic mecha | Health and Human Services, Department of / National Institutes of Health | 12/16/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $95,000 | Grant | Trans-NIH Recovery Act Research Support: We purchased the Qiagen Biorobot universal system for $95000. The package includes the biorobot, installation of the robot, reagents for the robot, training and application package. The application package contains protocols and the comprehensive accessor | Health and Human Services, Department of / National Institutes of Health | 12/14/2009 |
| BAYLOR COLLEGE OF MEDICINE | $44,573 | Grant | Trans-NIH Recovery Act Research Support: Obesity prevalence in the US and other developed countries has increased dramatically in recent decades. This trend is affecting individuals at every age, including women of child- bearing age. A major concern is that maternal obesity during pregnancy may | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The long term goal of the studies in this proposal is to understand the biology of pancreatic cell like progenitors derived from embryonic stem (ES) cells, with the intent of potentially using these cells for clinical applications such as islet transplan | Health and Human Services, Department of / National Institutes of Health | 12/28/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $99,928 | Grant | Trans-NIH Recovery Act Research Support: Obesity and associated diseases such as type II diabetes are increasing at an alarming rate throughout the world. These proposed experiments will investigate the cellular mechanisms contributing to the development of leptin resistance, a pathological sta | Health and Human Services, Department of / National Institutes of Health | 12/14/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of this project is to understand the molecular mechanisms responsible for the regulation of mitochondrial pyruvate dehydrogenase complex. The reaction catalyzed by pyruvate dehydrogenase complex plays a central role in general metabolis | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $40,000 | Grant | Trans-NIH Recovery Act Research Support: We have found that hyperinsulinemia, a state known to promote the progression/worsening of insulin resistance, is associated with increased plasma membrane (PM) cholesterol. Moreover, we have witnessed that reduction of this cholesterol protects against h | Health and Human Services, Department of / National Institutes of Health | 12/21/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA AT RIVERSIDE | $99,505 | Grant | Trans-NIH Recovery Act Research Support: This is a competitive revision responding to Enabling RPGs to Leverage NCRR Center and Center-Like Programs, which is part of the NOT-OD-09-058, NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. A major goal of th | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| UNIVERSITY OF WASHINGTON | $193,976 | Grant | Trans-NIH Recovery Act Research Support: This is a request for an Administrative Supplement on NIDDK grant 9R01DK083042 entitled Mechanisms of Diabetic Hyperphagia and Insulin Resistance (PI: Michael W. Schwartz, MD), which recently underwent successful competitive renewal. The rationale for th | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $39,287 | Grant | Trans-NIH Recovery Act Research Support: Supplemental funds are for purchases of items that will help facilitate mammalian cell experiments. They include an Isotemp CO2 incubator and Thermo Scientific 1300 Series Class A2 Hood. None of these items are currently found in the lab and are requested | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| YALE UNIVERSITY | $100,000 | Grant | Trans-NIH Recovery Act Research Support: My long range goal is to understand the mechanism of cytokinesis. We will pursue complementary cellular, biochemical and genetic strategies using the fission yeast Schizosaccharomyces pombe to address the following specific aims: Project 1. Dynamics of co | Health and Human Services, Department of / National Institutes of Health | 12/23/2009 |
| YALE UNIVERSITY | $68,000 | Grant | Trans-NIH Recovery Act Research Support: Our goal is to understand the molecular mechanisms controlling assembly and disassembly of actin filaments during cellular locomotion and endocytosis in terms of the rates of specific reactions. We will use a combination of biochemical, genetic and cellul | Health and Human Services, Department of / National Institutes of Health | 12/23/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $142,237 | Grant | Trans-NIH Recovery Act Research Support: The research proposed for this Supplement extends Aim 1 of the parent grant, which concerns functional epistasis and evolvability. The approach followed in the parent grant is to study the evolution of functional epistasis in terms of a modifier gene that | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $164,501 | Grant | Trans-NIH Recovery Act Research Support: Development of new chemical transformations useful for drug discovery and for interrogation of biological systems is the main goal of this project. Olefins provide a most efficient entry to organic compounds with diverse and controllable functionality. T | Health and Human Services, Department of / National Institutes of Health | 12/31/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $101,133 | Grant | Trans-NIH Recovery Act Research Support: Control of Histone mRNA Levels (ARRA) The long-term goal of this grant is to understand the molecular mechanisms which control the expression of histone mRNA levels during the mammalian cell cycle. Histone mRNAs are unique, ending in a conserved 3' stem-l | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $118,400 | Grant | Trans-NIH Recovery Act Research Support: The supplement funding to 3R01GM029860-28S1, entitled G?Cell adhesion and the regulation of Rho GTPasesG? will enable us to retain several researchers whose skills and research capabilities will significantly expedite our progress in meeting the goals of | Health and Human Services, Department of / National Institutes of Health | 12/31/2009 |
| NEW YORK MEDICAL COLLEGE | $141,354 | Grant | Trans-NIH Recovery Act Research Support: Our recent work shows that the binding of p12 to Pol ?3 causes a change in kpol-exo of nearly an order of magnitude. We can interpret this as a modulation of the conformational change that occurs during switching of the primer terminus from the pol to th | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| UNIVERSITY OF MIAMI | $132,705 | Grant | Trans-NIH Recovery Act Research Support: This Recovery Act administrative supplement provides funding to support additional investigators in our lab, and greatly enhances our productivity and ability to make progress on the critical, labor intensive functional studies for understanding the genet | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH | $134,285 | Grant | Trans-NIH Recovery Act Research Support: Purchase a new fluorescence microscope system and a particle size analyzer (dynamic light scattering, DLS). This equipment would greatly accelerate the pace of research supported by the parent grant. The parent grant centers on topoisomerase IV (Topo IV | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $97,441 | Grant | Trans-NIH Recovery Act Research Support: Chemotaxis, or directed cell movement toward a small molecule ligand, plays a key role in many cellular and physiological responses, including metastasis of cancer cells, movement of neutrophils and macrophage in immunity, migration of embryonic cells dur | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | $91,601 | Grant | Trans-NIH Recovery Act Research Support: Dividing cells must co-ordinate their rate of division with their rate of cell growth and protein synthesis. In many microbes, and in yeast in particular, this co-ordination is achieved by a size control mechanism: when the cell grows to a certain critica | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| TRUSTEES OF TUFTS COLLEGE INC | $121,435 | Grant | Trans-NIH Recovery Act Research Support: Synthesis of mRNA in eukaryotes, and its utilization in the cytoplasm, requires modification of the RNAG??s 3G?? end by addition of a poly(A) tail. This process also serves as an important point at which the cell can regulate the type and amount of mRNA d | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| COLD SPRING HARBOR LABORATORY ASSOCIATION, INC. | $95,137 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of this project is to develop a complete understanding of the spatial and temporal events involved in the regulation of RNA polymerase II transcription and pre-mRNA processing in living cells. An understanding of these parameters in the | Health and Human Services, Department of / National Institutes of Health | 12/11/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $586,053 | Grant | Trans-NIH Recovery Act Research Support: Award Title: Functional Coupling of Steps in Gene Expression The main objective of our Recovery Act Award is job preservation, creation of a new job, and expediting the research in our parental grant. The goal of the parental grant is to determine how the | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| ST. JUDE CHILDREN'S RESEARCH HOSPITAL | $114,694 | Grant | Trans-NIH Recovery Act Research Support: The cell division kinases (CDKs) have diverse functions, most of which are prominently linked to the control of cells division and/or transcription. Our laboratory identified a novel CDK subfamily, the CDK11 protein kinases previously known as the PITSLRE | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $156,624 | Grant | Trans-NIH Recovery Act Research Support: We have recently been able to demonstrate direct homology-dependent pairing of two DNA molecules independent of proteins under physiological conditions. The current administrative supplement is requested so that we can begin to pursue the biological impli | Health and Human Services, Department of / National Institutes of Health | 12/11/2009 |
| UNIVERSITY OF UTAH, THE | $156,453 | Grant | Trans-NIH Recovery Act Research Support: Iron, a cofactor of proteins involved in respiration, oxygen transport and DNA synthesis, is essential for cell growth and proliferation. Iron excess results in the generation of cytotoxic free radicals, and this has been associated with neurodegeneratio | Health and Human Services, Department of / National Institutes of Health | 12/25/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $73,722 | Grant | Trans-NIH Recovery Act Research Support: We will determine the effects of epigenetic modifications on replication origin activation and silencing within the immunoglobulin heavy chain (Igh) locus. We have established the location of many replication initiation sites throughout the Igh locus and | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| UNIVERSITY OF MARYLAND | $99,992 | Grant | Trans-NIH Recovery Act Research Support: In multicellular organisms, genomic stability and integrity is maintained by the combined actions of an accurate DNA replication machinery and a complex network of DNA repair pathways. DNA joining is an essential step in DNA replication, in DNA excision r | Health and Human Services, Department of / National Institutes of Health | 12/11/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $153,000 | Grant | Trans-NIH Recovery Act Research Support: The transition metal manganese plays a variety of important roles in biology and medicine. For example, a large number of enzymes use Mn(ll) in their catalytic centers. Along with Mn(ll), the higher oxidation states, Mn(lll) and Mn(IV), are also used in c | Health and Human Services, Department of / National Institutes of Health | 12/31/2009 |
| GEORGETOWN UNIVERSITY (THE) | $74,501 | Grant | Trans-NIH Recovery Act Research Support: The goal of this supplement is to complete Aim 3 of the parent grant, which is to solve the high resolution structure of DnaA protein in solution and bound to acidic lipid bilayers. This research will provide the first detailed structure of a membrane-ass | Health and Human Services, Department of / National Institutes of Health | 12/11/2009 |
| SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH | $125,664 | Grant | Trans-NIH Recovery Act Research Support: The goal of this supplemental application is to amplify and accelerate progress toward understanding the mechanism of the DNA damage checkpoint, a key objective of the parent grant ?Regulation of DNA Replication in S. pombe?. The DNA damage checkpoint is | Health and Human Services, Department of / National Institutes of Health | 12/25/2009 |
| ARIZONA STATE UNIVERSITY | $180,202 | Grant | Trans-NIH Recovery Act Research Support: The long term goal of this project is to understand the mechanism of the F1-ATPase. The FoF1 ATP synthase uses the nonequilibrium transmembrane electrochemical proton gradient derived from the oxidation of metabolites to drive the reaction ADP + Pi = ATP | Health and Human Services, Department of / National Institutes of Health | 12/31/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $92,541 | Grant | Trans-NIH Recovery Act Research Support: Control of developmental time is of fundamental importance to all multicellular organisms and is achieved with astonishing precision. The aim of this work is to understand the timing mechanisms that govern specific cell fate decisions during metazoan deve | Health and Human Services, Department of / National Institutes of Health | 12/11/2009 |
| OKLAHOMA MEDICAL RESEARCH FOUNDATION | $91,683 | Grant | Trans-NIH Recovery Act Research Support: The parent project for this supplement is designed to reveal fundamental aspects of cell cycle control and chromosome behavior in mitosis. Our studies on the living cell dynamics of the Sgo1 protein are not yet complete due to the necessary acquisition o | Health and Human Services, Department of / National Institutes of Health | 12/31/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $145,210 | Grant | Trans-NIH Recovery Act Research Support: One of the paradoxes of modern genetics is the contrast between the tremendous technological advances in sequencing and genotyping during the past decade and the slow progress in identifying genes for complex diseases. These diseases involve subtle disrup | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH | $208,314 | Grant | Trans-NIH Recovery Act Research Support: The research in the parent grant is aimed at understanding the factors that promote homologous recombination (HR) in mammalian cells and the consequences of impaired HR on organismal health. All three aims relate to the BRCA2 protein, which is also involv | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | $127,606 | Grant | Trans-NIH Recovery Act Research Support: The AsiA protein, a novel transcriptional regulator and product of the T4-bacteriophage asiA gene, is lethal to bacterial cells. The natural antibiotic tendencies of this protein, combined with the fact that it interacts with highly conserved elements of | Health and Human Services, Department of / National Institutes of Health | 12/31/2009 |
| LOYOLA UNIVERSITY | $88,610 | Grant | Trans-NIH Recovery Act Research Support: Parkinson's disease is a progressive neurodegenerative disease, where the dopaminergic neuronal cells in the brain slowly undergo cell death, leading to a decrease in dopamine production and causing muscle rigidity and tremors. Several proteins have been | Health and Human Services, Department of / National Institutes of Health | 12/11/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $101,067 | Grant | Trans-NIH Recovery Act Research Support: This supplement request outlines plans to hire personnel to accelerate the pace of discovery and to broaden the approach outlined in the original grant proposal to accommodate new discoveries from our lab and published work. | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $154,444 | Grant | Trans-NIH Recovery Act Research Support: PROJECT SUMMARY: The parent grant, R01GM0578089, provides for continued efforts in the expansion of the scope and depth of computational models of E. coli. Crucial to this area of work are high-throughput experiments which test model predictions and lea | Health and Human Services, Department of / National Institutes of Health | 12/21/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $92,930 | Grant | Trans-NIH Recovery Act Research Support: This proposal requests funds for an SFC (Supercritical Fluid Chromatography) instrument for analysis of enantioenriched samples. It will replace an outdated HPLC and greatly increase the tempo of this NIH supported research.This prediction was entirely c | Health and Human Services, Department of / National Institutes of Health | 12/31/2009 |
| BETH ISRAEL DEACONESS MEDICAL CENTER INC | $149,361 | Grant | Trans-NIH Recovery Act Research Support: Proline-directed phosphorylation (pSer/Thr-Pro) is a major signaling mechanism in the cell. Although these phosphorylation events had been long proposed to regulate protein function by inducing conformational changes, little was known about the nature, si | Health and Human Services, Department of / National Institutes of Health | 11/26/2009 |
| GEORGIA TECH RESEARCH CORPORATION | $126,242 | Grant | Trans-NIH Recovery Act Research Support: Parental project is using yeast prions as a model system for studying the cellular control of amyloid formation, propagation and clearance. Supplement project is related to Aim 4 of parental project (To study the role of the Golgi-to-ER trafficking, or GE | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $257,644 | Grant | Trans-NIH Recovery Act Research Support: As a normal aspect of animal development and homeostasis, programmed cell death (apoptosis) plays an essential role in maintaining the physiological balance of appropriate cell numbers by opposing uncontrolled cell proliferation. Abnormal inactivation or | Health and Human Services, Department of / National Institutes of Health | 12/25/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $154,525 | Grant | Trans-NIH Recovery Act Research Support: Despite significant advances in our understanding of how trinucleotide repeats cause disease, mechanisms underlying their unique property of genetic instability remain ill-defined. Of all CAG/polyglutamine diseases, spinocerebellar ataxia type 7 (SCA7) di | Health and Human Services, Department of / National Institutes of Health | 11/26/2009 |
| UNIVERSITY OF CHICAGO, THE | $105,300 | Grant | Trans-NIH Recovery Act Research Support: This renewal revision proposal focuses on a key problem in radiation biology, elucidating molecular determinants of checkpoint and repair responses to G1 DNA damage. Our model system is the budding yeast S. cerevisiae. We have studied the cell cycle delay | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| THOMAS JEFFERSON UNIVERSITY | $94,029 | Grant | Trans-NIH Recovery Act Research Support: Meiosis is the process used to generate haploids from diploids. The completion of meiosis is coupled to differentiation programs that form gametes that are capable of sexual fusion. Our previous results have defined a protein kinase network that control | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $271,969 | Grant | Trans-NIH Recovery Act Research Support: Alternative pre-mRNA splicing is a common mechanism for regulating gene expression in metazoans. Indeed, RNA processing is a conduit through which genomic information is transferred to proteomic information. Because most eukaryotic genes are split and h | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE | $101,634 | Grant | Trans-NIH Recovery Act Research Support: The project will expand our knowledge of the proteins protecting gametes from chromosomal abnormality, which is the leading cause of miscarriage and mental retardation. The cohesin proteins function in chromosome segregation, DNA repair and regulation of | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| UNIVERSITY OF ARIZONA | $95,330 | Grant | Trans-NIH Recovery Act Research Support: We are studying the molecular mechanisms of genome maintenance in herpes simplex virus-1 (HSV-1). HSV-1 is one of 8 human herpesviruses and serves as the prototype to understand the mechanism of replication of this medically important and biologically fas | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $150,983 | Grant | Trans-NIH Recovery Act Research Support: The control of gene expression at the level of transcription by RNA polymerase II is central to the life of the healthy cell and is frequently corrupted in disease. During each stage of the transcription cycle, initiation, elongation and termination, the | Health and Human Services, Department of / National Institutes of Health | 12/11/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $100,299 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of the proposed research is to better understand the molecular mechanisms that regulate RNA polymerase I (Pol I) transcription of ribosomal RNA. This rRNA becomes the major structural and functional component of ribosomes and its rate | Health and Human Services, Department of / National Institutes of Health | 12/11/2009 |
| DUKE UNIVERSITY | $118,828 | Grant | Trans-NIH Recovery Act Research Support: Unrepaired DNA damage is an important source of mutations, and such mutations are assumed to reflect error-prone lesion bypass during DNA replication. Although DNA damage-associated mutations also arise in nondividing (G0) cells, their mechanistic basis h | Health and Human Services, Department of / National Institutes of Health | 12/25/2009 |
| CALIFORNIA STATE UNIVERSITY AUXILIARY SERVICES, INC | $142,093 | Grant | Trans-NIH Recovery Act Research Support: The supplement enables the research team to deepen the analysis to include retention in Ph.D. programs and success in Ph.D. institutions. Proposed outcomes for the supplement: Collect follow-up career progress on 430 MORE funded students/alumni in 2004-20 | Health and Human Services, Department of / National Institutes of Health | 11/16/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $153,399 | Grant | Trans-NIH Recovery Act Research Support: Understanding how cells make developmental decisions is a central challenge in biology. In Arabidopsis, stem cells in the shoot apical meristem give rise to all of the above ground parts of the plants. A major developmental transition takes place when the | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $49,944 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Cell-cell signaling pathways, such as Wnt, Notch, and MAPK, are critical for the proper fate specification of most cells and tissues during animal development. These ancient and highly conserved pathways regulate devel | Health and Human Services, Department of / National Institutes of Health | 12/11/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $71,356 | Grant | Trans-NIH Recovery Act Research Support: Our overall goal is to achieve an understanding of the molecular mechanisms regulating cell divisions. The proposed studies utilize the model organism Caenorhabditis elegans to investigate the regulatory interactions between developmental signals and the | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $203,610 | Grant | Trans-NIH Recovery Act Research Support: Cell motility is a fundamental feature of living organisms. Actin, one of the most conserved and abundant proteins in eukaryotic cells, plays a key role in these processes, constantly transitioning among its various assembly forms. The goal of the ARRA su | Health and Human Services, Department of / National Institutes of Health | 12/28/2009 |
| BAYLOR COLLEGE OF MEDICINE | $116,416 | Grant | Trans-NIH Recovery Act Research Support: The Ku heterodimer is a high affinity DNA end binding protein that mediates various roles at the telomere, including telomere end protection, telomere length regulation, and telomeric silencing. Specific Aim 1 of 5R01GM077509 is to G?further define struc | Health and Human Services, Department of / National Institutes of Health | 12/25/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $66,750 | Grant | Trans-NIH Recovery Act Research Support: The association between Bcl-2 and cancer has been known for 20 years. But the biochemical mechanisms to explain why Bcl-2, found at translocation breakpoints in follicular lymphomas, why elevated Bcl-xL expression in many tumor types, and why herpes virus | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $163,243 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this project is to study translation initiation in eukaryotes. The goal of the work funded by this award is to investigate the scope and physiological relevance of mRNA-rRNA base pairing interactions during translation initiation by us | Health and Human Services, Department of / National Institutes of Health | 12/25/2009 |
| UNIVERSITY OF CALIFORNIA, SANTA CRUZ | $100,000 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Transcription is the first step of gene expression and a key point of biological regulation, which requires specific changes in chromatin structure and chemistry. The long-term objective of this proposal is to understa | Health and Human Services, Department of / National Institutes of Health | 12/25/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $71,965 | Grant | Trans-NIH Recovery Act Research Support: The project is a 4-celled factorial experiment designed to test the relative effects of separately and jointly introducing micro-credit (MC) and essential (health) services package (ESP) interventions on women's empowerment, economic well-being of th | Health and Human Services, Department of / National Institutes of Health | 11/19/2009 |
| UNIVERSITY OF UTAH, THE | $92,141 | Grant | Trans-NIH Recovery Act Research Support: 22q11 Chromosomal Microdeletion Syndrome; 22q11 Deletion Syndrome; 22q11DS; Ablation; Affect; Alleles; Allelomorphs; Antimorphic mutation; Apical Ectodermal Ridge; Apocrine Glands; Binding; Binding (Molecular Function); Biochemical; Biological Models; Bio | Health and Human Services, Department of / National Institutes of Health | 11/24/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $93,142 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Diabetic nephropathy (DN), the most lethal diabetic micro-vascular complication, occurs in approximately 30% of patients with diabetes. It is apparent, therefore, that prevention, definition of at risk populations and | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE | $38,962 | Grant | Trans-NIH Recovery Act Research Support: This request is for an equipment supplement (NOT-OD-09-056) for the project entitled G?Impaired Adipogenesis in Insulin Resistance: Pilot Clinical and In-Vitro StudiesG? (DK-80386-01) and seeks to accelerate the tempo of the research by investing in equi | Health and Human Services, Department of / National Institutes of Health | 12/21/2009 |
| EMORY UNIVERSITY | $100,001 | Grant | Trans-NIH Recovery Act Research Support: Urea plays an important role in the urinary concentrating mechanisms. In the past decade, significant progress has been made in understanding urea reabsorption and recycling in kidney mediated by two facilitated urea transporter genes, UT-A and UT-B. Howe | Health and Human Services, Department of / National Institutes of Health | 12/07/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $68,835 | Grant | Trans-NIH Recovery Act Research Support: The central hypothesis of this proposal is that consumption of a high fat diabetogenic diet during pregnancy and lactation (HFIU) 'programs' offspring weaned onto a low fat diet for increased susceptibility to Metabolic Syndrome and type 2 diabetes later | Health and Human Services, Department of / National Institutes of Health | 12/03/2009 |
| BAYLOR COLLEGE OF MEDICINE | $26,000 | Grant | Trans-NIH Recovery Act Research Support: This is an application for supplemental funding to accelerate the pace of the research project described in R21 DK082827-01, entitled ?Pathogenesis of Ketosis-Prone Diabetes?, to purchase an Indirect Calorimeter to pursue the research objectives proposed | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| WAKE FOREST UNIVERSITY | $87,136 | Grant | Trans-NIH Recovery Act Research Support: One of the most compelling and unresolved issues of visual processing is the role of the massive cortical feedback that occurs in a number of sites in the visual system. Activation of this feedback is thought to underlie processes such as attention. It ma | Health and Human Services, Department of / National Institutes of Health | 12/14/2009 |
| UT-BATTELLE, LLC | $278,725 | Grant | Trans-NIH Recovery Act Research Support: NIH Grant Number -- 3R21HG004764-02S1: DNA Transport and Sequencing through a Quadrupole Gate: This award provides funding from the National Institutes of Health (NIH). The purpose of this project is to develop a high speed device for sequencing a sing | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $83,179 | Grant | Trans-NIH Recovery Act Research Support: Lesch Nyhan Disease (LND) represents an ideal model human disease in which to study the mechanisms by which even single gene defects produce very complex disruptions of normal genomic, proteomic, biochemical and metabolomic changes function. LND is a thor | Health and Human Services, Department of / National Institutes of Health | 12/25/2009 |
| MOREHOUSE SCHOOL OF MEDICINE, INC., THE | $215,516 | Grant | Trans-NIH Recovery Act Research Support: The collaborative clinical translational research (CTR) and career development program creates a model for senior residents and junior faculty who are interested in pursuing clinical and translational research as part of a competitive research-intensive s | Health and Human Services, Department of / National Institutes of Health | 12/09/2009 |
| IMAGINARIUM, THE | $199,982 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement seeks to enhance an existing NCRR SEPA grant titled North Star (Phases I and II), the aims of which include; 1) increasing the number of Alaskans from educationally and/or economically disadvantaged backgrounds, particularly | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| BATTELLE MEMORIAL INSTITUTE | $397,168 | Grant | Trans-NIH Recovery Act Research Support: Award Title: A Proteomics Platform for Quantitative, Ultra-High Throughput, and Ultra-Sensitive Biomarker Discovery Award Purpose: This supplement will speed the development of a transformative, advanced analytical platform for much higher throughput p | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY | $91,218 | Grant | Trans-NIH Recovery Act Research Support: New equipment is required to increase the productivity of workers engaged in research studying the mechanisms and function of endocytic membrane trafficking. Some of this new equipment (i.e., new generation CCD cameras) will have capabilities that allow u | Health and Human Services, Department of / National Institutes of Health | 12/08/2009 |
| PURDUE UNIVERSITY | $39,960 | Grant | Trans-NIH Recovery Act Research Support: The proposed project continues a programmatic investigation of the neural mechanisms of feeding and body weight regulation. The long-range goal of the project is to provide information needed for treating ingestive disorders, notably obesity, and a variet | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $66,500 | Grant | Trans-NIH Recovery Act Research Support: Growth hormone (GH) has been used for many years to promote growth in children with GH deficiency and more recently for other disorders that retard growth. GH also affects body metabolism and has been approved for GH-deficient adults and AIDS-associated | Health and Human Services, Department of / National Institutes of Health | 12/15/2009 |
| GEORGETOWN UNIVERSITY (THE) | $78,280 | Grant | Trans-NIH Recovery Act Research Support: Vasoconstrictor PGs activating the TP receptor (R) include PGH2, TxA2 and isoprostanes (Iso). NO or peroxynitrite (ONOO), its reaction product with superoxide anion (02'), can activate cyclooxygenase (COX) whereas O2and ONOO can inactivate prostacyclin sy | Health and Human Services, Department of / National Institutes of Health | 12/08/2009 |
| UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON | $85,000 | Grant | Trans-NIH Recovery Act Research Support: Request for a Multiplex analysis system to accelerate the tempo of investigations in diabetic complications. This system will allow for identification of a broader range of signaling pathways involved in the hyperglycemia and will also provide a novel di | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| EMORY UNIVERSITY | $100,001 | Grant | Trans-NIH Recovery Act Research Support: REGULATION OF SODIUM IN TIGHT EPITHELIA. This award is an administrative supplement to R37 DK037963 G?Regulation of Sodium Transport in Tight EpitheliaG?. The parent grant is in the third year of a five year extension of a Merit Award. The aims of the ori | Health and Human Services, Department of / National Institutes of Health | 12/07/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $271,091 | Grant | Trans-NIH Recovery Act Research Support: Diabetes is a world-wide major cause of morbidity and mortality that is associated with disturbances in cell function that result in the loss of glucose-stimulated insulin secretion for control of blood glucose. Recent studies demonstrated an associatio | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| BETH ISRAEL DEACONESS MEDICAL CENTER INC | $100,000 | Grant | Trans-NIH Recovery Act Research Support: Notice Number - NOT-OD-09-058 Notice Title: NIH Announces the Availability of Recovery Act Funds for Competitive Renewal Applications. Type 2 diabetes is characterized by impaired insulin action in tissues such as muscle, liver, and adipose tissue. Our lo | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| DUKE UNIVERSITY | $36,809 | Grant | Trans-NIH Recovery Act Research Support: The overarching goal of our NIH-funded project 5R37DK46492-17, now in its 17th year, has been to gain fundamental insights into the biochemical and molecular mechanisms involved in acute regulation of insulin secretion by glucose and other metabolic fuels | Health and Human Services, Department of / National Institutes of Health | 12/03/2009 |
| BETH ISRAEL DEACONESS MEDICAL CENTER INC | $202,131 | Grant | Trans-NIH Recovery Act Research Support: Uncoupling protein-2 (UCP2) is a mitochondrial protein that negatively regulates ATP production. In pancreatic ?-cells, UCP2 affects glucose-stimulated insulin secretion. UCP2 is also expressed in the brain. In glucose-excited neurons (specifically, POMC | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $183,585 | Grant | Trans-NIH Recovery Act Research Support: Leptin, an adipocyte-derived hormone, signals via its receptor (LepRb) in the brain to control energy balance, neuroendocrine function, and glucose homeostasis in concert with peripheral energy (fat) stores. As obesity and its complications (e.g., diabet | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| BRANDEIS UNIVERSITY | $61,832 | Grant | Trans-NIH Recovery Act Research Support: Funds were received to purchase an upgrade for a fluorescence microscope to allow real-time imaging in 3 dimensions. A new piezo-electric stage and UV filters witll be purchased to enable the laboratory to examine the positions of fluyorescently labeled | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $93,564 | Grant | Trans-NIH Recovery Act Research Support: This supplemental project will enable assembly and operation of a custom-built total internal fluorescence (TIRF) microscope to accelerate research on the parent project, Structure/function of transcription complex RNA hairpins, using single-molecule micr | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH | $140,000 | Grant | Trans-NIH Recovery Act Research Support: Purchase a new fluorescence microscope system and a particle size analyzer (dynamic light scattering, DLS). This equipment would greatly accelerate the pace of research supported by the parent grant. The parent grant centers on topoisomerase IV (Topo IV | Health and Human Services, Department of / National Institutes of Health | 12/11/2009 |
| NANORELEASE TECHNOLOGIES, LLC | $73,059 | Grant | Trans-NIH Recovery Act Research Support: The proposed work had two Specific Aims. One focused on the scientific approach, while the other defined the professional impact and experience. Specific Aim 1 was to improve the production and testing of critical components of the encapsulation process | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| BIOINVISION INC. | $349,125 | Grant | Trans-NIH Recovery Act Research Support: We are poised to greatly benefit from an administrative supplement to develop cryo-imaging. We have made significant progress towards specific aims, including the creation of software and a prototype at BioInVision, Inc. We have also demonstrated exciting | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| GENETAG TECHNOLOGY INC | $124,025 | Grant | Trans-NIH Recovery Act Research Support: universal qPCR probes for influenza,supplement | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| BETASTEM THERAPEUTICS INC | $326,697 | Grant | Trans-NIH Recovery Act Research Support: The long term goal is to develop an efficient, safe clinical treatment for diabetic retinopathy using stem cells from the patient's bone marrow or blood that have been activated to repair damaged vessels in the eye. Diabetic retinopathy remains theleading | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| ARTANN LABORATORIES INC | $219,494 | Grant | Trans-NIH Recovery Act Research Support: Osteoporosis induced by aging as well as a side effect of certain drugs is a serious public health problem. The lack of adequate means for early detection of bone deterioration is the most critical issue in the problem of minimization of side effects of p | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| PROGENRA, INC | $284,002 | Grant | Trans-NIH Recovery Act Research Support: Muscle atrophy (wasting), also known as myopathy, is a clinical complication of many diseases, e.g., cancer, AIDS, and diabetes, as well as a natural consequence of inactivity and aging; it significantly diminishes quality of life. Progenra has developed | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| ARTANN LABORATORIES INC | $299,994 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of the project is to bring to the market a new tool for prostate cancer screening, the Prostate Mechanical Imager (PMI), which provides real time 3-D reconstruction of prostate capturing its geometrical and mechanical characteristics an | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| ALDERON BIOSCIENCES, INC. | $282,240 | Grant | Trans-NIH Recovery Act Research Support: This proposed NCI Funded Administrative Supplement--Announcement Number: NOT-09-056 for Innovative Tools for the Molecular Diagnosis of Cancer is designed to do research that directly contributes toward development of a societally-useful cancer gene meas | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| MOLECULAR KINETICS INC | $199,962 | Grant | Trans-NIH Recovery Act Research Support: In this supplement proposal, we requested funding to hire 3 additional full-time staff scientists for the remaining duration of the parent grant (~14 months). Their work is directly related to specific aim 3 milestone 1 of the parent grant, which is to c | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| INTRA MEDICAL IMAGING LLC | $400,000 | Grant | Trans-NIH Recovery Act Research Support: TESTING OF THE BETA CAMERA FOR DETECTION OF CANCER TISSUE ATT HE MARGIN OF THE RESECTED TUMOR. | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| BANDEMAR NETWORKS LLC | $25,905 | Grant | Trans-NIH Recovery Act Research Support: BanDeMar Networks proposes an Administrative Supplement to its ongoing development of Advanced Training Technology for the National Institute of Environmental Health Science (NIEHS) Worker Education and Training Program (WETP) (Parent Grant SBIR Phase II | Health and Human Services, Department of / National Institutes of Health | 6/17/2009 |
| BANDEMAR NETWORKS LLC | $117,429 | Grant | Trans-NIH Recovery Act Research Support: BanDeMar Networks proposes an Administrative Supplement to its ongoing development of Advanced Training Technology for the National Institute of Environmental Health Science (NIEHS) Worker Education and Training Program (WETP) (Parent Grant SBIR Phase II | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| VISIONQUEST BIOMEDICAL | $32,066 | Grant | Trans-NIH Recovery Act Research Support: SUMMARY ABSTRACT The principal objective is to demonstrate clinically a commercially viable, low-cost, high-resolution fundus camera that: is easy to use, i.e., consistent with the operation of current fundus cameras; has a field of view (FOV) that is typ | Health and Human Services, Department of / National Institutes of Health | 7/10/2009 |
| VISIONQUEST BIOMEDICAL | $58,717 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): This proposed project is motivated by two observations. First, broad-scale screening of diabetics for retinopathy is economically prohibitive without the introduction of computer-assisted diagnosis of retinal images. S | Health and Human Services, Department of / National Institutes of Health | 7/10/2009 |
| TEMPLE UNIVERSITY | $98,327 | Grant | Trans-NIH Recovery Act Research Support: The research proposed in this application intends to provide new biological markers and therapeutic strategies to fight the vascular complications of obesity and insulin resistance. According to the American Heart Association, cardiovascular disease (CDV) | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | $44,000 | Grant | Trans-NIH Recovery Act Research Support: This is a request for an administrative supplement to the parent grant DK067558 entitled Acinus: A Novel Corepressor of RAR-Regulated Gene Expression under the program for administrative supplements utilizing recovery act funds. We are requesting funds | Health and Human Services, Department of / National Institutes of Health | 11/20/2009 |
| FORT PECK COMMUNITY COLLEGE | $80,000 | Grant | Trans-NIH Recovery Act Research Support: Diabetes Education in Tribal Schools (DETS) is a collaboration of the National Institute of Diabetes and Digestive adnm Kidney Disease (NIDDK) and other federal partners with eight Tribal Colleges and Universities (TCUs). The main objective was to develop | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| CANKDESKA CIKANA COMMUNITY COLLEGE | $80,000 | Grant | Trans-NIH Recovery Act Research Support: Increase outreach to schools on the Health Is Life in Balance curriculum developed in teh original DETS grant. | Health and Human Services, Department of / National Institutes of Health | 1/01/2009 |
| KEWEENAW BAY INDIAN COMMUNITY (INC) | $80,000 | Grant | Trans-NIH Recovery Act Research Support: Diabetes Education in Tribal Schools (DETS) is a collaboaration of the NIDDK and other federal partners with eight TCUs. The main objective was to develop a national science-based diabetes prevention education curriculum for Native American students in gr | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| LEECH LAKE TRIBAL COLLEGE, INC. | $80,000 | Grant | Trans-NIH Recovery Act Research Support: Woodlands Wisdom Project is a Confederation of the following institutions: College of Menominee Nation, Turtle Mountain Community College, Leech Lake Tribal College, Fond du Lac Tribal & Community College, Lac Courte Oreilles Ojibwe Community College, Whi | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF MIAMI | $88,220 | Grant | Trans-NIH Recovery Act Research Support: STRATEGIES TO IMPROVE LONG TERM ISLET GRAFT SURVIVAL (ADMINISTRATIVE SUPPLEMENT. The current funding of the parent grant is reserved for direct patient costs; funding for these costs are disbursed only as the patients are transplanted by the participatin | Health and Human Services, Department of / National Institutes of Health | 12/28/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $88,000 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the supplement is to purchase a Leica epifluorescence microscope. The microscope will allow us to image and record data obtained in the parent project which is focused on characterizing the transcriptional regulation of the embryonic and a | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $92,330 | Grant | Trans-NIH Recovery Act Research Support: Background: In a) OVE26 mice with type 1 diabetes, b) C57BI/6 mice with diet induced obesity and insulin resistance, and c) db/db mice with type 2 diabetes mellitus, we have found increased renal expression of the transcriptional factors, i) the sterol re | Health and Human Services, Department of / National Institutes of Health | 12/08/2009 |
| THE VANDERBILT UNIVERSITY | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The proposed administrative supplement proposes to obtain additional funds for The ASSESS-AKI (ASsessment, Serial Evaluation, and Subsequent Sequelae in Acute Kidney Injury) Consortium. This particular administrative supplement is in response to NIH Notic | Health and Human Services, Department of / National Institutes of Health | 11/26/2009 |
| KAISER FOUNDATION HOSPITALS | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The vast majority of published studies on acute kidney injury have focused only on clinical outcomes that occur during the index hospitalization and have been limited by various methodological challenges. Relatively little is known about long-term clinica | Health and Human Services, Department of / National Institutes of Health | 11/29/2009 |
| UNIVERSITY OF MARYLAND | $25,000 | Grant | Trans-NIH Recovery Act Research Support: The Human Microbiome Project (HMP) is an NIH Roadmap program that will produce unprecedented amounts of information about the microbial communities living on and within humans. The objective of our current work is to provide a Data Analysis and Coordinati | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| UNIVERSITY OF MARYLAND | $995,688 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (15) Translational Research and specific Challenge Topic, 151-AI-106: Translational research focused on high priority pathogens (influenza) and basic research focused on resistance mechanisms. Pandemic influ | Health and Human Services, Department of / National Institutes of Health | 11/25/2009 |
| FLORIDA INTERNATIONAL UNIVERSITY | $648,737 | Grant | Trans-NIH Recovery Act Research Support: G?Brief Intervention for Marijuana Use among Latino Youth is a two-year research project designed to develop and test a school-based, brief intervention for marijuana using, Hispanic/Latino 10th & 11th graders. Clinical trials support the effectiveness of | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| CRESS LLC | $93,640 | Grant | Trans-NIH Recovery Act Research Support: To hire analysts to examine the data of children's speech development | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| CRESS LLC | $93,640 | Grant | Trans-NIH Recovery Act Research Support: To hire people to perform acoustic analyses of children's speech | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF MISSOURI SYSTEM | $5,350,000 | Grant | National Center for Research Resources, Recovery Act Construction Support: The University of Missouri-Columbia (MU) has experienced tremendous research growth in recent years. Extramural research awards increased 72% from $73.2 million in FY1998 to $126.1 million in FY2002. Much of this funding was a awarded for biomedical science... Show more | Health and Human Services, Department of / National Institutes of Health | 10/16/2009 |
| PRICEWATERHOUSECOOPERS LLP | $919,100 | Contract | : The purpose of this work is to assist NIH OFM in oversight of Recovery Act financial management reporting and performance, including the establishment, development and implementation of NIH guidance to identify and mitigate risk and ensure the correction | Health and Human Services, Department of / National Institutes of Health | 10/30/2009 |
| WESTAT, INC. | $2,240,090 | Contract | : The funds will cover the performance of standardizing and creating common infrastructure for the CTEP multi-center clinical trial networks for the ADOPTion of New Technologies for Remote Data Capture & Protocol Authoring (ADOPT) project. | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| MONTEFIORE MEDICAL CENTER | $799,986 | Contract | : An NCI Clinical Trial entitled, A randomized, double-blind, placebo- controlled phase II study of FOLFOX +/- GDC-0449 in advanced gastric and gastroesophageal junction (GEJ) carcinoma | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| SAIC FREDERICK, INC | $103,000,000 | Contract | : The Cancer Knowledge Cloud will connect and share information generated through NCI genomic atlas projects, the caHUB tissue acquisition network, the NCI functional Biology Consortium, NCI patient Characterization Center, the NCI pre-clinical Development | Health and Human Services, Department of / National Institutes of Health | 11/23/2009 |
| LOGICAL TECHNICAL SERVICES CORP. | $21,028 | Contract | : Technical services to assist the NIH/OPERA/eRA with the execution of NIH grant support implementation of the required NIH oversight related to the American Recovery and Reinvestment Act of 2009 (ARRA) at NIH's Institutes and Centers supported by OER. Ass | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| AEROTEK, INC. | $79,768 | Contract | : Services of individuals to assist in coordination of collection, analysis, and reporting of international research & Training. | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| JEFFERSON CONSULTING GROUP, LLC | $144,963 | Contract | : The primary objective is to develop an acquisition workload model to predict the workload that will be generated based on an anticipated influx of funds and other key factors, and to project a commensurate staffing level. | Health and Human Services, Department of / National Institutes of Health | 12/08/2009 |
| GRANT THORNTON LLP | $1,000,000 | Contract | : Contractor shall perform Program Integrity Investigations to include a professional audit, program analysis, and other support services to assess, audit, review, and report on allegations of misues of federal funds provided to the NIH under the American R | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| OLYMPUS AMERICA INC. | $58,781 | Contract | : Olympus IX Automated Microscope for Live Cell Imaging and NIR Imaging | Health and Human Services, Department of / National Institutes of Health | 11/04/2009 |
| OLYMPUS AMERICA INC. | $78,751 | Contract | : Olympus BX61 Automated Microscope for Fluorescence | Health and Human Services, Department of / National Institutes of Health | 12/10/2009 |
| BECTON, DICKINSON AND COMPANY | $166,840 | Contract | : Purchase of FACSCANTO II Flow Cytometer | Health and Human Services, Department of / National Institutes of Health | 6/29/2009 |
| FISHER SCIENTIFIC COMPANY L.L.C. | $373 | Contract | : Laboratory Supplies | Health and Human Services, Department of / National Institutes of Health | 12/11/2009 |
| SAIC FREDERICK, INC | $5,000,000 | Contract | : The Chemical Biology Consortium (CBC) will identify a cadre of members with the biological expertise and capability to rapidly develop sufficient information both in vitro and in vivo to determine the potential of novel discoveries, from the Cancer Genome | Health and Human Services, Department of / National Institutes of Health | 12/22/2009 |
| ALKEN, INC. | $31,382 | Contract | : One FastSCAN Scorpion Digitizer Short Ranger System | Health and Human Services, Department of / National Institutes of Health | 11/20/2009 |
| SABLE SYSTEMS INTERNATIONAL, INC | $23,035 | Contract | : 7- AD-2 Activity Detectors 1- RM-8 Multiplexer V5 & Assessories (power cords and cables and manuals) 1- Mux Scan Board & Assesories & Assessories (power cords and cables and manuals) 7- RC-M Miniature Respirometer Chamber 7- AD-2 Actvity Detector & Asse | Health and Human Services, Department of / National Institutes of Health | 6/24/2009 |
| METASYSTEMS GROUP, INC | $169,900 | Contract | : Metafer Scanning System | Health and Human Services, Department of / National Institutes of Health | 6/26/2009 |
| ANDOR TECHNOLOGY | $27,400 | Contract | : PURCHASE OF SCIENTIFIC CAMERA - EMCCD CAMERA, PCI CONTROLLER CARD AND RELATED SOFTWARE | Health and Human Services, Department of / National Institutes of Health | 6/26/2009 |
| ROPER SCIENTIFIC INC | $46,100 | Contract | : LAB EQUIPMENT | Health and Human Services, Department of / National Institutes of Health | 6/29/2009 |
| SAIC FREDERICK, INC | $18,068,932 | Contract | : The Cancer Genome Atlas (TCGA) - A large scale, collaborative effort to characterize the genomic changes that occur in cancer. Currently, the three aspects of the project are to establish a.) a biospecimen core resource to collect clinical data on thousa | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| SAIC FREDERICK, INC | $20,000,000 | Contract | : Therapeutically Applicable Research to Generate Effective Treatments (TARGET)- project to identify genomic targets in childhood cancers that can be used to develop more effective treatments. The goal is to catalogue somatic DNA changes that are associate | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| PROMEGA CORPORATION | $22,143 | Contract | : purhcase of Maxwell 16 instrument | Health and Human Services, Department of / National Institutes of Health | 8/26/2009 |
| PROMEGA CORPORATION | $18,961 | Contract | : purchase of Glomax Luminometer | Health and Human Services, Department of / National Institutes of Health | 6/24/2009 |
| LEICA MICROSYSTEMS INC | $8,130 | Contract | : mICRO iNJECTOR | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| BIBST ENTERPRISES, INC. | $34,380 | Contract | : BAF301 Vacuum System upgrade replacing obsolete, energy inefficient, water cooled compressor, cryo pump system with new, energy efficient,air cooled turbo-molecular pump system fully installed, integrated and commissioned to provide Freeze fracture labora | Health and Human Services, Department of / National Institutes of Health | 8/24/2009 |
| SAIC FREDERICK, INC | $17,000,000 | Contract | : Develop a universal influenza vaccine. The following activities will be performed at the Vaccine Pilot Plant which was specifically developed to rapidly translate research into vaccine products for clinical trials: Production of vaccine Production of m | Health and Human Services, Department of / National Institutes of Health | 12/22/2009 |
| SAIC FREDERICK, INC | $60,000,000 | Contract | : The Cancer Human Biobank (caHUB) - This is a national, standardized , biospecimen resource for the collection of human tissues which are a critical resource for cancer research. Contracts will be established with medical research adn healthcare entities | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| SAIC FREDERICK, INC | $6,700,000 | Contract | : CTRP Support: Architecture and Development: Provide Technical analysis and Architectural Support for the NCI Clinical Trial Reporting Program (CTRP). Development will focus on design and specifications needed for the CTRP interoperable NCI Enterprise Serv | Health and Human Services, Department of / National Institutes of Health | 11/23/2009 |
| SAIC FREDERICK, INC | $75,135,000 | Contract | : NCI's Community Cancer Centers Program (NCCCP) - The network of community hospitals is a complex pilot program whose mission is, through research, to determine ways to bring state of the art cancer care and clinical trials to patients in their local comm | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| SAIC FREDERICK, INC | $8,000,000 | Contract | : The immediate goal of the New Therapeutic Molecules Project is to prevent short-term gaps in the supply of sufficient materials to treat patients on NCI-supported clinical studies. The long-term goal is to develop sufficient efficiencies in production and | Health and Human Services, Department of / National Institutes of Health | 12/22/2009 |
| SAIC FREDERICK, INC | $2,000,000 | Contract | : To increase the probability of identifying agents worthy of further investigation, it is necessary to augment available trans-NIH chemical libraries with chemicals and libraries that can only be obtained from external sources. To address this need, the CB | Health and Human Services, Department of / National Institutes of Health | 11/23/2009 |
| SAIC FREDERICK, INC | $2,000,000 | Contract | : Procure through purchase/license new commercial off the shelf (COTS) software to integrate with the Cambridge Soft software utilized for the collection of all data generated on Chemical Biology Consortium projects that are conducted within the NCI, at SAI | Health and Human Services, Department of / National Institutes of Health | 11/23/2009 |
| LEICA MICROSYSTEMS INC | $175,200 | Contract | : Purchase of Leica SMD FLIM system upgrade | Health and Human Services, Department of / National Institutes of Health | 11/02/2009 |
| NIKON INSTRUMENTS INC. | $100,837 | Contract | : Nikon Eclipse 80i Fluorescence Microscope | Health and Human Services, Department of / National Institutes of Health | 12/10/2009 |
| VEECO METROLOGY INC. | $129,990 | Contract | : BIOSCOPE CATALYST MODEL SPC-090311-03 SPM UPGRADE | Health and Human Services, Department of / National Institutes of Health | 12/09/2009 |
| CARL ZEISS MICROIMAGING, INC. | $205,555 | Contract | : Laboratory Equipment | Health and Human Services, Department of / National Institutes of Health | 12/22/2009 |
| APPLIED BIOSYSTEMS, LLC | $164,214 | Contract | : Lab equipment & supplies. Sale of 7900H Fast Real Time PCR System and TAQMAN Open Array Genotyping Platform | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| A-TEK INC | $283,088 | Contract | : NOTE: This project was funded on 11/05/09 and began 11/16/09. The A-TEK Team has been awarded the requirement to provide support for the USDA Rural Development (RD) Application, Design, Development, Testing and Helpdesk. The A-TEK Team will support RD | Health and Human Services, Department of / National Institutes of Health | 11/05/2009 |
| APPLIED BIOSYSTEMS, LLC | $67,500 | Contract | : Single sale of lab equip : catalog 7900HT | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| CDW GOVERNMENT, INC. | $4,804 | Contract | : Purchase of information technology commercial items to improve agency operations or to fulfill agency requirements. Deliverables detailed elsewhere in this report. | Health and Human Services, Department of / National Institutes of Health | 7/31/2009 |
| TISHMAN CONSTRUCTION CORPORATION OF MARYLAND | $10,732,419 | Contract | : This second phase of the Center for Information Technology (CIT) Building No. 12 Infrastructure Upgrade will provide the minimum redundancy required achieving the designed system capacity (2880 KVA NO-Break & 1400 KVA Short-Break). Once Commissioned the D | Health and Human Services, Department of / National Institutes of Health | 9/27/2010 |
| GTSI CORP. | $5,850 | Contract | : Lenovo Laptops | Health and Human Services, Department of / National Institutes of Health | 7/31/2009 |
| MCCONNELL GROUP, INC. THE | $2,533,160 | Contract | : The award was for the purchase of cutting edge laboratory equipment designed to assist in research conducted by DHHS/NIH/NHBLI. | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| VISIONARY TECHNOLOGY SOLUTIONS, INC. | $11,625 | Contract | : Upgrades to the Budget Office Module System (BOMS) and the Computerized Grants Management System (CGMS). Modification of systems to provide Stimulus Flagging and Reporting capabilities. Add Stimulus and ELSI Flags to BOMS. Add Stimulus K CAN to CGMS DBs. | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| CDW GOVERNMENT, INC. | $8,232 | Contract | : Purchase of information technology commercial items to improve agency operations or to fulfill agency requirements. Deliverables detailed elsewhere in this report. | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| CAPINTEC INC | $193,750 | Contract | : dual hot cells | Health and Human Services, Department of / National Institutes of Health | 9/27/2009 |
| CARESTREAM HEALTH INC | $802,532 | Contract | : NIH currently uses Carestream PACS 10.1 Clustered Workflow Mgr (WFM) Servers (Sun 880 platforms) with attached EMC CX400 RAID. All image data is located on a CX400 RAID with DLT tape backup & storage at an offsite location. NIH also has Carestream PACS v1 | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| GENERAL ELECTRIC COMPANY | $144,480 | Contract | : PACS Visualization Upgrade- The AW Server delivers distributed 3D Visualization capabilities throughout the Enterprise and at any remote reading location. It utilizes State of the Art thin client technology to convert virtually any PC to a high-end 3D pos | Health and Human Services, Department of / National Institutes of Health | 12/29/2009 |
| MITTAL, KAMAL K | $34,000 | Contract | : RECOVERY Services for SRB/NIA in identifying reviewers for applications submitted to NIA for review and preparation of summary statements | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| LEICA MICROSYSTEMS INC | $36,866 | Contract | : purchase of CM3050S Cryostat | Health and Human Services, Department of / National Institutes of Health | 11/16/2009 |
| UVP, LLC | $18,000 | Contract | : Laboratory equipment | Health and Human Services, Department of / National Institutes of Health | 10/26/2009 |
| UNIVERSITY OF ROCHESTER | $2,232,889 | Contract | : Operation of a facility for the study of influenza viruses, vaccines and antimicrobials in human subjects. | Health and Human Services, Department of / National Institutes of Health | 11/03/2009 |
| NEXCELOM BIOSCIENCE LLC | $49,180 | Contract | : Labatory Equipment | Health and Human Services, Department of / National Institutes of Health | 10/15/2009 |
| DISS LLC | $390,806 | Contract | : ARRA Intramural Research Equipment: This requirement provides consolidated equipment for the NIAID (National Institute of Allergy and Infectious Diseases) Intramural Research Program for influenza studies. The deliverables include: integrated remote tele | Health and Human Services, Department of / National Institutes of Health | 10/23/2009 |
| STEMCELL TECHNOLOGIES INC | $47,405 | Contract | : Recovery/ARRA Equipment Order For RoboSep Cell Separator Catalogue # 20000 | Health and Human Services, Department of / National Institutes of Health | 12/16/2009 |
| APPLIED BIOSYSTEMS, LLC | $431,210 | Contract | : Lab equipment & supplies. Sale of SOLiD system 110V (includes SOLiD Fragment Instrument Install Kit). Catalogue no. 4381967 | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| APPLIED BIOSYSTEMS, LLC | $7,000 | Contract | : Lab power supply | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| MDB, INC. | $227,940 | Contract | : Conduct analysis of research advances as reported by the ARRA-funded grant supplements; modify, update and maintain the NIEHS SRP data system to incorporate ARRA-funded grant outcomes; and develop web content and other printed materials describing the ARR | Health and Human Services, Department of / National Institutes of Health | 10/01/2009 |
| METASYSTEMS GROUP, INC | $21,100 | Contract | : Software Upgrade MC-167 | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| ESCALON MEDICAL CORP. | $14,500 | Contract | : Vegasys Clinical Chemistry System | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| BIOTEK INSTRUMENTS, INC. | $28,696 | Contract | : LABORATORY EQUIPMENT & SUPPLIES | Health and Human Services, Department of / National Institutes of Health | 11/05/2009 |
| LEICA MICROSYSTEMS INC | $134,443 | Contract | : Purchase of DM600 Confocal Microscope | Health and Human Services, Department of / National Institutes of Health | 10/30/2009 |
| Z-TECH CORPORATION | $484,530 | Contract | : FOR ERA SYSTEMS ENGINEERING SUPPORT SERVICES | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| Z-TECH CORPORATION | $213,900 | Contract | : For eRA Systems Engineering/NBS Integration | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| SCIENCE APPLICATIONS INTERNATIONAL CORPORATION | $61,000 | Contract | : Provide software development and support services to the NIH Office of Extramural Research (OER) for the Electronic Research Administration (eRA) systems and databases with respect to ARRA grant recipient reporting. At the beginning of each quarter, coll | Health and Human Services, Department of / National Institutes of Health | 11/13/2009 |
| AFFYMETRIX, INC. | $200,800 | Contract | : Purchase of an Affymetrix GeneChip Scanner 3000 7G System. | Health and Human Services, Department of / National Institutes of Health | 11/12/2009 |
| LIFE MEASUREMENT, INC. | $99,675 | Contract | : PEA POD Infant Body Composition System | Health and Human Services, Department of / National Institutes of Health | 11/12/2009 |
| PAIGE INDUSTRIAL SERVICES, INC. | $300,390 | Contract | : Replace mechanical systems replace mechanical syatems NIH campus wide | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| PERKINS + WILL VIRGINIA, INC. | $5,468,821 | Contract | : ARRA-Porter II -A/E contract for construction administration & Post Design Phase Services, Bldg 35 Phase 2 (east addition to existing structure) | Health and Human Services, Department of / National Institutes of Health | 12/01/2009 |
| PC MALL GOV, INC. | $4,473 | Contract | : Puchase of computer equipment One (1) DELL Precision Workstation | Health and Human Services, Department of / National Institutes of Health | 12/08/2009 |
| STEMCELL TECHNOLOGIES INC | $47,405 | Contract | : Equipment Order for RoboSep Cell Separator | Health and Human Services, Department of / National Institutes of Health | 6/29/2009 |
| GOVERNMENT SCIENTIFIC SOURCE, INC. | $127,587 | Contract | : 1-XF24-2 Analzer Module $68,922.00 1-XF24-2 Controller $28,541.00 1-CO2 Detection Module $18,426.00 1-Plate Prep Station $11,698.00 | Health and Human Services, Department of / National Institutes of Health | 6/29/2009 |
| MEDICAL GRAPHICS CORPORATION | $47,883 | Contract | : Quote #MP060801; Medgraphics Ultima Cardio2 (TM); Pulmonary Exercise Systems w/Optional Combined 12-Lead ECG; w/Accessories. Includes a 12-month warranty. | Health and Human Services, Department of / National Institutes of Health | 6/30/2009 |
| BECTON, DICKINSON AND COMPANY | $16,000 | Contract | : Purchase of FACSLoader | Health and Human Services, Department of / National Institutes of Health | 7/02/2009 |
| RHEO MEDITECH INC. | $19,000 | Contract | : Goods Description: RheoScan-D 300 Quantity: 1 Set Amount: USD 19,000.00 Accounting Info: 08010920092DA0.2009.26.N100.HNN0200000 C.I.00203.506.9999.319H.610001.9999.9999.9999 | Health and Human Services, Department of / National Institutes of Health | 7/09/2009 |
| SIEMENS INDUSTRY, INC. | $24,650 | Contract | : Contractor shall remove and replace the two (2) exiting mixing boxes and replace with two (2) new electronic mixing boxes at the NIH offices in Bathesda. | Health and Human Services, Department of / National Institutes of Health | 12/02/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $54,000 | Grant | Trans-NIH Recovery Act Research Support: This is a study of molecular mechanisms involved in GILZ regulation that appears to dictate the activity state of ENaC, an ion channel that critically controls blood pressure. | Health and Human Services, Department of / National Institutes of Health | 12/21/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $54,000 | Grant | Trans-NIH Recovery Act Research Support: Use shRNA techniques to understand the role of the nectin signaling pathway in apoptosis and obstructive nephropathy. Evaluate polarity during organ development in kidney and lung using real-time microscopy of organs in culture. | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $54,000 | Grant | Trans-NIH Recovery Act Research Support: In the current proposal, we will incorporate recently published data and results presented at the Conference of Retroviruses and Opportunistic Infections to guide our investigation of inflammation in the host. | Health and Human Services, Department of / National Institutes of Health | 12/17/2009 |
| NORTHWESTERN UNIVERSITY | $94,224 | Grant | Trans-NIH Recovery Act Research Support: These additional studies will accelerate and extend the research goals of the parent grant and will result in economic stimulus by providing salary support for research personnel, contracting commercial services, and purchasing supplies. Moreover, these | Health and Human Services, Department of / National Institutes of Health | 11/19/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $69,162 | Grant | Trans-NIH Recovery Act Research Support: The kidney, like many epithelial organs, consists mainly of tubules lined by a monolayer of polarized epithelial cells. Though we have learned a great deal about the genes that control kidney development, we know much less about the mechanisms by which c | Health and Human Services, Department of / National Institutes of Health | 12/21/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $96,938 | Grant | Trans-NIH Recovery Act Research Support: This grant is for the procurement of an equipment set up for performing electrophysiology studies. This electrophysiology equipment will accelerate the successful completion of the parent grant. | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $116,828 | Grant | Trans-NIH Recovery Act Research Support: This research develops methods to study the mechanisms that cells use to distribute signals in order to communicate over short distance and long. These essential mechanisms are involved in processes such as vasculogenesis, neuronal patterning and immune | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY | $99,800 | Grant | Trans-NIH Recovery Act Research Support: Inherited mutations in the gene encoding BRCA2 are associated with a predisposition to early-onset breast and ovarian cancers. The underlying basiss of the tumorigenesis is thought to be linked to defects in homologous recombination which results in ra | Health and Human Services, Department of / National Institutes of Health | 11/26/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $133,006 | Grant | Trans-NIH Recovery Act Research Support: Eukaryotic cells must ensure that the hundreds to thousands of replication origins in their genomes initiate replication at most once per cell cycle. Failure to prevent re-initiation can cause genetic alteration that might contribute to carcinogenesis. Pr | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $99,997 | Grant | Trans-NIH Recovery Act Research Support: The purchase of a Zeiss Axio Imager M2 motorized microscope will allow applications previously only achievable by confocal microscopy at roughly a third of the comparable cost. This equipment will accelerate our research aimed at understanding the roles o | Health and Human Services, Department of / National Institutes of Health | 12/28/2009 |
| CLAFLIN UNIVERSITY | $214,897 | Grant | Trans-NIH Recovery Act Research Support: Research enhancement (R15) award to detrmine protein fold specific rules in enzymatic adaptation to temperature constraints. To understand how structure adapts to selctive pressures of high and low temperature and understand what amino acid changes are ne | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| ALASKA COMMUNITY ACTION ON TOXICS | $323,884 | Grant | Trans-NIH Recovery Act Research Support: ENVIRONMENTAL HEALTH AND JUSTICE IN NORTON SOUND, ALASKA: The ARRA funds are for environmental health research in North West Alaska. Alaska Community Action on Toxics (ACAT) has utilized the parent grant award through NIEHS to focus on known and previousl | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| BIOFORTIS, INC. | $200,000 | Grant | Trans-NIH Recovery Act Research Support: Bioscience Research Intergration software platform | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| CELL SIGNALING TECHNOLOGY, INC. | $150,018 | Grant | Trans-NIH Recovery Act Research Support: The parent grant supports the development of PhosphoSitePlus-? (PSP) a cutting-edge web-based biomedical research used weekly by thousands of researchers around the world. PSP aggregates information about protein post-translational modifications (PTM | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| S. A. C. N. A. S. | $159,257 | Grant | Trans-NIH Recovery Act Research Support: With the generous support of NIGMS over the past two decades SACNAS has already maximized services and programs for underrepresented minorities beyond the annual conference, and more recently to incorporate year round initiatives such as the SACNAS Leader | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $39,530 | Grant | Trans-NIH Recovery Act Research Support: This award sought to allow for the expansion of the established aim of the parent R03 grants, to compare the patient judgment of laryngeal sensation to the actual state of the larynx by adding an instrumental measure of laryngeal sensation. This addition | Health and Human Services, Department of / National Institutes of Health | 1/27/2010 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $5,084,481 | Grant | Trans-NIH Recovery Act Research Support: This award, entitled ?Intracellular pathogens and innate immunity,? is a program project grant that consists of investigators from UC Berkeley, UCSF and Stanford Universities. There are four projects and three cores to support the research. Each investi | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| SOCIAL & SCIENTIFIC SYSTEMS, INC. | $255,702 | Grant | Trans-NIH Recovery Act Research Support: The funds will be used to complete the HLA-typing of DNA specimens obtained from children participating in Pediatric AIDS Clinical Trials Group / International Maternal Pediatric Adolescent AIDS Clinical Trials Group protocols which will provide data to d | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| SOCIAL & SCIENTIFIC SYSTEMS, INC. | $1,130,883 | Grant | Trans-NIH Recovery Act Research Support: The goal of this project is to increase recruitment and retention of underrepresented and underserved populations into AIDS Clinical Trials Group (ACTG) clinical trials. The ACTG is committed to enrollment of domestic clinical trial participants in propor | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $60,000 | Grant | Trans-NIH Recovery Act Research Support: We are planning to use HPLC in conjunction with mass spectrometry rather than trying to sort out all o f the phosphorylation events using radiolabels. The improved method will allow us to track natively phosphorylated MAP2K's and study their activity tow | Health and Human Services, Department of / National Institutes of Health | 12/31/2009 |
| UNIVERSITY OF CENTRAL FLORIDA | $6,960 | Grant | Trans-NIH Recovery Act Research Support: This grant provides summer research experiences for undergraduate students in molecular biology and microbiology in health-related scientific research. | Health and Human Services, Department of / National Institutes of Health | 7/10/2009 |
| UNIVERSITY OF CENTRAL FLORIDA | $6,960 | Grant | Trans-NIH Recovery Act Research Support: This grant provides summer research experiences for undergraduate students in molecular biology and microbiology in health-related scientific research. | Health and Human Services, Department of / National Institutes of Health | 7/10/2009 |
| SCIENCE APPLICATIONS INTERNATIONAL CORPORATION | $300,000 | Contract | : Provide support for the Enhancing Peer Review Project that will address technical requirements identified by the NIH Peer Review Working Groups. These enhancements will promote the Peer Review Oversight committee's priorities to engage the best reviewers | Health and Human Services, Department of / National Institutes of Health | 2/17/2010 |
| MOUNT SINAI SCHOOL OF MEDICINE | $99,533 | Grant | Trans-NIH Recovery Act Research Support: EryP are the first differentiated cell type to form in the mammalian embryo and play a vital role in oxygen delivery and in generating shear forces necessary for normal vascular development. Despite their abundance and indispensable functions, the develop | Health and Human Services, Department of / National Institutes of Health | 1/18/2010 |
| UROVALVE INC | $370,875 | Grant | Trans-NIH Recovery Act Research Support: The objectives of this proposed Phase II SBIR project are to refine the Surinate-? Bladder Management System to make it easier for the patient to operate, more reliable and easier to insert and extract than the prototype that was tested in the Phase I SBI | Health and Human Services, Department of / National Institutes of Health | 1/06/2010 |
| NEW YORK UNIVERSITY (INC) | $121,405 | Grant | Trans-NIH Recovery Act Research Support: These investigations will focus on microRNA-mediated gene regulation in mammalian cells, with the goal of understanding the mechanisms by which microRNAs repress translation and expedite the deadenylation and decay of their mRNA targets as well as the con | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| TRUSTEES OF BOSTON UNIVERSITY | $162,500 | Grant | Trans-NIH Recovery Act Research Support: During this period, we have focused on Specific Aim 1 of the proposal. In particular, we have exchanged the first lumenal loops of Glut4 and cellugyrin, and we have prepared stably transfected lines of 3T3-L1 cells in order to study the intracellular loc | Health and Human Services, Department of / National Institutes of Health | 3/15/2010 |
| UNIVERSITY OF FLORIDA | $85,500 | Grant | Trans-NIH Recovery Act Research Support: Shortcourse G-CSF as immunomodulatory therapy for type 1 diabetes: a pilot study | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| UNIVERSITY OF MASSACHUSETTS | $489,250 | Grant | Trans-NIH Recovery Act Research Support: Project Title: Illumina Genome Analyzer IIx for UMass Deep Sequencing Core. Description: This application requests funding for an Illumina (Solexa) Genome Analyzer IIx massively parallel sequencer to enhance the capacity and capabilities of the Deep Sequ | Health and Human Services, Department of / National Institutes of Health | 2/18/2010 |
| SCRIPPS RESEARCH INSTITUTE, THE | $174,290 | Grant | Trans-NIH Recovery Act Research Support: The goal of this project is use rat lines selected for high and low stress responses to investigate the neurobiological bases of individual differences in vulnerability to stress by gene espression profiling coupled with a systems biology gene network ana | Health and Human Services, Department of / National Institutes of Health | 1/15/2010 |
| MCCONNELL GROUP, INC. THE | $2,533,160 | Contract | : The award was for the purchase of cutting edge laboratory equipment designed to assist in research conducted by DHHS/NIH/NHBLI. | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| CHILDRENS HOSPITAL OF PHILADELPHIA | $61,523 | Grant | Trans-NIH Recovery Act Research Support: The overall aim of the Obesity and Surgical Outcomes (OBSOS) study is to improve the outcomes of obese patients who must undergo general, orthopedic, vascular or urological surgery. Obesity has been implicated in predisposing patients to worse surgical ou | Health and Human Services, Department of / National Institutes of Health | 1/07/2010 |
| UNIVERSITY OF FLORIDA | $69,095 | Grant | Trans-NIH Recovery Act Research Support: Liver cirrhosis has an increasing incidence and prevalence in the United States and is closely associated with the development of hepatocellular carcinoma, which has a dismal long-term prognosis. The mechanisms that lead to dysregulated cirrhotic hepatocy | Health and Human Services, Department of / National Institutes of Health | 2/01/2010 |
| UNIVERSITY OF WISCONSIN SYSTEM | $148,500 | Grant | Trans-NIH Recovery Act Research Support: The Wisconsin Diabetes Registry Study (WDRS) is following one of very few population-based cohorts with type 1 diabetes in the United States. The cohort is unique in being comprehensively described from the time of diagnosis during 1987-1992 until now, wi | Health and Human Services, Department of / National Institutes of Health | 3/22/2010 |
| BANYAN BIOMARKERS INC. | $45,917 | Grant | Trans-NIH Recovery Act Research Support: To accelerate the production of diagnostic panel for liver injury and validate the utility of the panel with an emphasis on drug-induced hepatoxicity. | Health and Human Services, Department of / National Institutes of Health | 3/10/2010 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $364,688 | Grant | Trans-NIH Recovery Act Research Support: Defining the kinetics of molecular interactions between biomolecules has become an essential application for fundamental microbiology and immunology research and translational drug discovery. This shared instrumentation grant requests funding to purchase | Health and Human Services, Department of / National Institutes of Health | 1/07/2010 |
| MOUNT SINAI SCHOOL OF MEDICINE | $53,968 | Grant | Trans-NIH Recovery Act Research Support: With the widespread introduction of antiretroviral therapy, HIV has become a chronic disease, and HIV- related kidney disease has emerged as an important cause of morbidity and mortality. Both HIV infection and antiretroviral therapy have been associated | Health and Human Services, Department of / National Institutes of Health | 1/01/2010 |
| THE VANDERBILT UNIVERSITY | $482,490 | Grant | Trans-NIH Recovery Act Research Support: We request funds to purchase a Becton Dickinson custom multilaser LSRII flow cytometer for polychromatic analytical flow cytometry. The current facilities at Vanderbilt University provide a strong infrastructure for conduct of highly technical flow cytome | Health and Human Services, Department of / National Institutes of Health | 3/04/2010 |
| YALE UNIVERSITY | $165,500 | Grant | Trans-NIH Recovery Act Research Support: Hypoglycemia remains the major factor limiting the use of intensified insulin therapy that has been shown to prevent complications in type 1 diabetes (T1DM). This MERIT extension proposal continues studies focused on the mechanisms that trigger glucose co | Health and Human Services, Department of / National Institutes of Health | 3/15/2010 |
| BIOMEDICAL RESEARCH INSTITUTE OF NEW MEXICO | $57,404 | Grant | Trans-NIH Recovery Act Research Support: Quarterly activities for the project ?C-reactive Protein suppresses the immune system through Fc gamma receptors.? Grant number: 1F31AI080178-01A1 During this period I have been enrolled in Immunology Journal Club, Cellular and Molecular Basis of Disease | Health and Human Services, Department of / National Institutes of Health | 6/02/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $109,900 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Cell signaling mediated by the Hedgehog (Hh) family of secreted proteins plays crucial roles in animal development and human diseases. The Hh pathway is operating in a similar way among organisms ranging from insects t | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| APPLIED BIOSYSTEMS, LLC | $30,225 | Contract | : singel sale of lab equpment catalog: 4351105 | Health and Human Services, Department of / National Institutes of Health | 2/22/2010 |
| PENNSYLVANIA STATE UNIVERSITY, THE | $106,487 | Grant | Trans-NIH Recovery Act Research Support: A number of important health-related conditions including, but not limited to, aging, physical inactivity, nutrient imbalance or insufficiency, hormonal imbalance or insufficiency, and a number of disease states are associated with a dramatic loss of skel | Health and Human Services, Department of / National Institutes of Health | 12/31/2009 |
| LUNA INNOVATIONS INCORPORATED | $555,726 | Grant | Trans-NIH Recovery Act Research Support: Nanotechnology, the use of nanomaterials at the molecular level, is a multidisciplinary scientific field undergoing exponential growth and has broad applications among all divisions of science. One form of nanomaterials, fullerenes, are soc | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| CAPITAL TECHNOLOGY INFORMATION SERVICES, INC. | $514,780 | Contract | : ADOPT (ADOPTion of New Technologies for Remote Data Capture & Protocol Authoring) Common Infrastructure Support under Operation and Support of the Cancer Therapy Evaluation Program's Informatic and Computer Support. Activities will include Program Managem | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| FISHER SCIENTIFIC COMPANY L.L.C. | $8,637 | Contract | : NIH Bethesda MD - Laboratory Supplies | Health and Human Services, Department of / National Institutes of Health | 12/17/2009 |
| FISHER SCIENTIFIC COMPANY L.L.C. | $217 | Contract | : Laboratory & hospital supplies for New England Medical Center | Health and Human Services, Department of / National Institutes of Health | 12/02/2009 |
| FISHER SCIENTIFIC COMPANY L.L.C. | $214 | Contract | : Laboratory & hospital supplies for New England Medical Center | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| FISHER SCIENTIFIC COMPANY L.L.C. | $436 | Contract | : Laboratory & hospital supplies for New England Medical Center | Health and Human Services, Department of / National Institutes of Health | 12/15/2009 |
| FISHER SCIENTIFIC COMPANY L.L.C. | $90 | Contract | : Laboratory & hospital supplies for New England Medical Center | Health and Human Services, Department of / National Institutes of Health | 12/15/2009 |
| FISHER SCIENTIFIC COMPANY L.L.C. | $428 | Contract | : New England Med CTR Hospital Laboratory Supplies | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| FISHER SCIENTIFIC COMPANY L.L.C. | $28 | Contract | : New England Med CTR Hospital Laboratory Supplies | Health and Human Services, Department of / National Institutes of Health | 12/15/2009 |
| FISHER SCIENTIFIC COMPANY L.L.C. | $47 | Contract | : New England Med CTR Hospital Laboratory Supplies | Health and Human Services, Department of / National Institutes of Health | 12/15/2009 |
| BOSTON BIOMEDICAL RESEARCH INSTITUTE, INC. | $47,096 | Grant | Trans-NIH Recovery Act Research Support: This ARRA award is a supplement to support summer stipends for two undergraduate research students who will receive training in biomedical research while contributing to ongoing research for the parent grant. | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $141,598 | Grant | Trans-NIH Recovery Act Research Support: Mammalian cells have evolved sophisticated DNA repair systems to correct mispaired or damaged bases and extrahelical loops. However, at hairpin-structure forming CAG repeats, the MSH2/MSH3 protein causes rather than corrects mutation, resulting in CAG ex | Health and Human Services, Department of / National Institutes of Health | 12/25/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $522,044 | Grant | Trans-NIH Recovery Act Research Support: The objective of this project is to create, implement, and evaluate training programs for emerging clinical researchers that blend online and face-to-face instruction to advance health-related research. The aims are to: 1) Develop blended online and face- | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $599,933 | Grant | Trans-NIH Recovery Act Research Support: The project will strengthen partnerships between the Community Engagement Programs funded by CTSA awards to two institutions, UCSF and Stanford, and their local health departments serving a racially and ethnically diverse population of 2.6 million. The pr | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $216,768 | Grant | Trans-NIH Recovery Act Research Support: We are requesting funds to purchase a PicoQuant FluoTime 200 fluorescence lifetime instrument. This instrument will augment and ultimately replace our 13 year old PTI LaserStrobe fluorescence lifetime system, which was originally purchased by the OHSU De | Health and Human Services, Department of / National Institutes of Health | 3/18/2010 |
| NATIONAL ASSOCIATES, INC. | $70,737 | Contract | : DATA ENTRY OPERATORS TO PROVIDE ADMIN SUPPORT | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| LOGICAL TECHNICAL SERVICES CORP. | $2,189,089 | Contract | : Due to the critical public need for H1N1 therapies, vaccines, and diagnostics, four projects have been initiated within NIAID to combat this disease. Each project is based on a 24-month delivery schedule to provide a series of results within this period | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY | $79,173 | Grant | Trans-NIH Recovery Act Research Support: The rod cell is highly polarized and compartmentalized in both morphology and function. A number of genetic disorders affecting the retina are manifested in the trafficking of the visual pigment rhodopsin and the morphology of the light sensing organelle | Health and Human Services, Department of / National Institutes of Health | 1/07/2010 |
| CASE WESTERN RESERVE UNIVERSITY | $80,000 | Grant | Trans-NIH Recovery Act Research Support: This award is a supplement to GM079191 (Structural Studies of G Protein) and has been provided for the express intent to purchase equipment related to this project. All funds related to this supplement have been fully expended. | Health and Human Services, Department of / National Institutes of Health | 2/12/2010 |
| UNIVERSITY OF MASSACHUSETTS | $813,032 | Grant | Trans-NIH Recovery Act Research Support: Overview The Massachusetts Department of Mental Health (DMH) Forensic Transition Team (FTT), a case management based re-entry program, has been in existence for over 10 years. Although there have been descriptive studies documenting favorable short-term | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $237,750 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Evolutionary pressure has favored mechanisms that allow the body to efficiently store nutrients as fat when food is abundant as a safeguard against occasional famine. With the dramatic changes in modern lifestyle inclu | Health and Human Services, Department of / National Institutes of Health | 2/02/2010 |
| UNIVERSITY OF FLORIDA | $219,750 | Grant | Trans-NIH Recovery Act Research Support: These R56 bridge funding award is intended to retain two full time employees as well as mouse breeding colonies and critical cell lines generated by this 10 year project during the preparation and resubmission of the competing renewal application. | Health and Human Services, Department of / National Institutes of Health | 1/11/2010 |
| SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH | $34,471 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Many chromosomal abnormalities and genetic instability arising in cancer and other human diseases are caused by defects in chromosomal replication. Chromosomal replication not only requires the proper function of the b | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $89,185 | Grant | Trans-NIH Recovery Act Research Support: APO-1 Antigen; APO-1 Cell Surface Antigen; Address; After Care; After-Treatment; Aftercare; Allogenic; Antibodies; Apoptosis; Apoptosis Antigen 1; Apoptosis Pathway; Apoptotic; Assay; B blood cells; B-Cells; B-Lymphocytes; Bioassay; Biologic Assays; Biolo | Health and Human Services, Department of / National Institutes of Health | 1/14/2010 |
| SAN DIEGO STATE UNIVERSITY FOUNDATION | $395,491 | Grant | Trans-NIH Recovery Act Research Support: The ability to conduct real-time, sequential in viva imaging of small animals is an important extension of animal models developed to study human diseases, and a prerequisite to translation of basic science discoveries to clinical applications. This propo | Health and Human Services, Department of / National Institutes of Health | 3/11/2010 |
| UNIVERSITY OF NEBRASKA | $500,000 | Grant | Trans-NIH Recovery Act Research Support: The University of Nebraska-Lincoln (UNL) flow cytometry core facility requests funds to replace its FACS Vantage SE flow cytometer/cell sorter (which is obsolete) with a FACS Aria II three laser special order system. This new instrumentation will provide | Health and Human Services, Department of / National Institutes of Health | 2/20/2010 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $242,672 | Grant | Trans-NIH Recovery Act Research Support: This Administrative Supplement request will investigate the impact of the APOBEC3 proteins in the evolution of HIV drug resistance. Despite the fact that highly specific and active drugs have been developed to inhibit viral replication, HIV inevitably o | Health and Human Services, Department of / National Institutes of Health | 1/15/2010 |
| GOVERNMENT SCIENTIFIC SOURCE, INC. | $11,587 | Contract | : 1-C1000 THERMAL CYCLER 48/48 CATALOG# 1851048 $7,938.90 1-C1000 MJ MINI CYCLER 48-WELL CATALOG # PTC1148 $3,647.60 | Health and Human Services, Department of / National Institutes of Health | 2/24/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $69,512 | Grant | Trans-NIH Recovery Act Research Support: Biological rhythms coordinate the timing of our internal bodily functions. Examples are temporal variations in temperature, hormone levels, aspects of disease (increased incidence of myocardial infarctions and strokes in the morning, nocturnal exacerbatio | Health and Human Services, Department of / National Institutes of Health | 1/27/2010 |
| SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE | $573,000 | Grant | Trans-NIH Recovery Act Research Support: The emerging obesity pandemic is driving an alarming increase in the prevalence of insulin resistant forms of diabetes. The mechanisms whereby obesity leads to insulin resistance remain to be fully elucidated. Chronic caloric excess leads to increased del | Health and Human Services, Department of / National Institutes of Health | 1/11/2010 |
| UNIVERSITY OF ILLINOIS | $94,616 | Grant | Trans-NIH Recovery Act Research Support: Currently, five (5) faculty researchers in Department of Cancer Biology and Pharmacology at the University of Illinois College of Medicine at Peoria are working on twelve (12) NIH funded projects (with an additional 1 pending and 1 in transfer), as well a | Health and Human Services, Department of / National Institutes of Health | 3/25/2010 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $996,817 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (06) Enabling Technologies and specific Challenge Topic, 06-CA-103 Synthetic Biology. In this proposal, the Shen and Califano laboratories will combine their complementary expertise in stem cell biology and | Health and Human Services, Department of / National Institutes of Health | 3/19/2010 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $499,706 | Grant | Trans-NIH Recovery Act Research Support: A group of 27 NIH funded investigators at UCSD requests funds to purchase a FEI Tecnai G2 Spirit BioTWIN transmission electron microscope (TEM) to continue to meet the ongoing and future demands of a variety of researchers within the Department of Cellula | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| NORTHWESTERN UNIVERSITY | $106,750 | Grant | Trans-NIH Recovery Act Research Support: Transport of organelles and macromolecular complexes through the cytoplasm is essential for every eukaryotic cell. This process is performed by motor proteins that use the chemical energy of ATP hydrolysis to move their cargo along microtubules and actin | Health and Human Services, Department of / National Institutes of Health | 1/14/2010 |
| UNIVERSITY OF SOUTH ALABAMA | $14,506,327 | Grant | National Center for Research Resources, Recovery Act Construction Support: A PROPOSAL TO CONSTRUCT A NEW, STAND-ALONE 25,800 SQUARE FOOT LABORATORY OF INFECTIOUS DISEASES (LID) BUILDING AT THE UNIVERSITY OF SOUTH ALABAMA (USA) THAT WILL HOUSE NEW BSL-2, BSL-3, AND ANIMAL BSL-3 (ABSL-3) LABORATORIES. . NEW SPACE IS NEEDED TO SUSTAI... Show more | Health and Human Services, Department of / National Institutes of Health | 2/04/2010 |
| YALE UNIVERSITY | $165,500 | Grant | Trans-NIH Recovery Act Research Support: Membrane fusion is central to many areas of endocrine and exocrine physiology, and imbalances in these processes give rise to important diseases, such as diabetes. As a result of the work supported by this grant during the current cycle of funding, the co | Health and Human Services, Department of / National Institutes of Health | 3/22/2010 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $31,500 | Grant | Trans-NIH Recovery Act Research Support: The increased risk of developing heart disease, strokes, and diabetes with excess adipose tissue is well known; obesity is generally caused by excess caloric intake. Less well appreciated are the devastating effects on health of the lipodystrophies. In th | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| UNIVERSITY OF ROCHESTER | $55,700 | Grant | Trans-NIH Recovery Act Research Support: Funds will be used to purchase a microplate reader capable of UV/visible absorbance measurements, fluorescence, luminescence, FRET (fluorescence resonance energy transfer), BRET (bioluminescence resonance energy transfer), TRF (time resolved fluorescence) | Health and Human Services, Department of / National Institutes of Health | 1/16/2010 |
| MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE INC | $464,440 | Grant | Trans-NIH Recovery Act Research Support: Funding is requested for the purchase of an Amnis ImageStream multispectral imaging flow cytometer which can perform high-throughput analysis of cell populations and cellular processes. This instrument essentially combines the visual power of microscopy, | Health and Human Services, Department of / National Institutes of Health | 3/11/2010 |
| MAYO CLINIC | $32,997 | Grant | Trans-NIH Recovery Act Research Support: A key objective of the current funding of the ROl grant is to advance our understanding of the regulation of muscle mitochondrial biogenesis and its role in type 2 diabetes. The proposal also addresses the gap in our understanding on regulation of synthes | Health and Human Services, Department of / National Institutes of Health | 2/02/2010 |
| UNIVERSITY OF ROCHESTER | $364,762 | Grant | Trans-NIH Recovery Act Research Support: This shared instrumentation proposal seeks funds to purchase a state-of-the-art BIAcore T100 instrument for the University of Rochester. No instrument comparable to the T100 is available in the Rochester area. An in- house Reichert SR7000 instrument has l | Health and Human Services, Department of / National Institutes of Health | 1/07/2010 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $424,236 | Grant | Trans-NIH Recovery Act Research Support: Acute joint injury often results in the development of osteoarthritis. Because osteoarthritis affects 1 in 3 individuals in the United States, there is an urgent need to delineate the biomarker response after acute joint injury so the incipient stages of | Health and Human Services, Department of / National Institutes of Health | 3/26/2010 |
| UNIVERSITY OF LOUISVILLE | $99,963 | Grant | Trans-NIH Recovery Act Research Support: We purchased the Seahorse and this grant is FULLY COMPLETED. | Health and Human Services, Department of / National Institutes of Health | 2/01/2010 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $53,158 | Grant | Trans-NIH Recovery Act Research Support: The obesity epidemic has been linked to increasing incidence of diabetes, cardiovascular disease and other complications. Diet and exercise are essential to weight management; however, it is obvious that many patients would require drug treatment to achie | Health and Human Services, Department of / National Institutes of Health | 1/14/2010 |
| SANFORD RESEARCH / USD | $239,980 | Grant | Trans-NIH Recovery Act Research Support: The Neuronal Ceroid Lipofuscinoses (NCL) is probably the most frequent group of progressive inherited neurodegenerative diseases with childhood onset. They can start at all ages and progression is characterized by one or more of the following symptoms: vi | Health and Human Services, Department of / National Institutes of Health | 3/15/2010 |
| UNIVERSITY OF WISCONSIN SYSTEM | $307,477 | Grant | Trans-NIH Recovery Act Research Support: In vertebrates, cilia are indispensible cellular organelles that regulate cell development and signaling in response to changes in the external environment. Cilia are found on many different human cell types and play a role in a variety of cell functions. | Health and Human Services, Department of / National Institutes of Health | 3/10/2010 |
| THE VANDERBILT UNIVERSITY | $479,279 | Grant | Trans-NIH Recovery Act Research Support: We proposed the purchase of a Thermo Scientific LTQ Orbitrap XL ETD hybrid mass spectrometer equipped with both high-energy collisional dissociation (HCD) and electron transfer dissociation (ETD) capabilities. The instrument will employ an Eksigent Nano U | Health and Human Services, Department of / National Institutes of Health | 3/25/2010 |
| CASE WESTERN RESERVE UNIVERSITY | $6,679 | Grant | Trans-NIH Recovery Act Research Support: Phosphoenolpyruvate carboxykinase (PEPCK) was discovered in 1953 by Utter and Kurahashi, yet more than 50 years later its metabolic role is still being resolved. PEPCK is a cataplerotic enzyme, which catalyzes the key reaction in hepatic and renal glucone | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $99,000 | Grant | Trans-NIH Recovery Act Research Support: Glucagon initiates the gluconeogenic program in hepatocytes by activating the cAMP signaling pathway, while insulin inhibits hepatic gluconeogenesis. A key regulator of this process is TORC2 (also known as CRTC2), which functions as a molecular switch in | Health and Human Services, Department of / National Institutes of Health | 2/19/2010 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $15,000 | Grant | Trans-NIH Recovery Act Research Support: This grant funds the procurement of a Chromatography equipment set up to supplement parent grant number 1K08HD058599-01 | Health and Human Services, Department of / National Institutes of Health | 2/25/2010 |
| UNIVERSITY OF ILLINOIS | $126,676 | Grant | Trans-NIH Recovery Act Research Support: The aims of this project are (1) to understand the molecular basis of the diverse pharmacology of estrogens, including the selective estrogen receptor modulators (SERMs) and antiestrogens, (2) to develop novel inhibitors of estrogen action that act by blo | Health and Human Services, Department of / National Institutes of Health | 1/14/2010 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $99,985 | Grant | Trans-NIH Recovery Act Research Support: This supplement will examine two new mechanisms underlying the trafficking of neurokinin 1 receptor (NK1R) and calcitonin receptor-like receptor/receptor activity modifying protein 1(CLR/RAMP1), which lead to the activation of hypersensitivity to pain in | Health and Human Services, Department of / National Institutes of Health | 12/29/2009 |
| MICHIGAN STATE UNIVERSITY | $32,000 | Grant | Trans-NIH Recovery Act Research Support: The overall aim of the parent grant is the development of protein structure and refinement methods that can routinely achieve near-experimental accuracy. While the paranet grant is focused on the prediction of soluble proteins, supplemental support is sou | Health and Human Services, Department of / National Institutes of Health | 3/24/2010 |
| UNIVERSITY SYSTEM OF NEW HAMPSHIRE | $84,880 | Grant | Trans-NIH Recovery Act Research Support: The goal of this research is to elucidate the mechanisms that govern mRNA degradation. The principal pathway for mRNA degradation in yeast involves an initial poly(A) deadenylation, followed by 5' end decapping, and 5'-3' RNase digestion. The rate of dead | Health and Human Services, Department of / National Institutes of Health | 1/15/2010 |
| NEW YORK UNIVERSITY (INC) | $75,000 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): T cells play a central role in the adaptive antigen-specific immune response to invading pathogens and cancer while largely avoiding self-reactivity (autoimmunity). These cellular functions are mediated by interaction | Health and Human Services, Department of / National Institutes of Health | 1/21/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $71,491 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Abnormal pancreatic -cell function can have a profound impact on glucose homeostasis, with insufficient secretion of insulin, coupled with marked resistance to its actions by target tissues, resulting in type-2 diabete | Health and Human Services, Department of / National Institutes of Health | 1/19/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $95,655 | Grant | Trans-NIH Recovery Act Research Support: The long range objective of our laboratory is to understand the cellular and molecular mechanisms by which signaling pathways and downstream transcription factors coordinate the specification of adrenocortical cells within the adrenal gland. Our strategy | Health and Human Services, Department of / National Institutes of Health | 1/28/2010 |
| CHICAGO STATE UNIVERSITY | $91,537 | Grant | Trans-NIH Recovery Act Research Support: MBRS SCORE Program at Chicago State University | Health and Human Services, Department of / National Institutes of Health | 12/01/2009 |
| UNIVERSITY AUXILIARY AND RESEARCH SERVICES CORPORATION | $130,890 | Grant | Trans-NIH Recovery Act Research Support: A major goal of the CSUSM MARC Phase II Curriculum Improvement grant is to integrate quantitative and computational knowledge and skills throughout the entire undergraduate biology curriculum. Calculus is potentially an important tool for many science co | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| TIRF TECHNOLOGIES INC | $18,000 | Contract | : lgTIRFM-170 Lightguige based Total Internal REflection Fluorescence Microscopy system with accessories. | Health and Human Services, Department of / National Institutes of Health | 6/26/2009 |
| UNIVERSITY OF PITTSBURGH THE | $24,543 | Contract | : The University of Pittsburgh has been awarded a contract to provide tumor types to the NCI for The Cancer Genome Atlas (TCGA) project. Specifically this award is to fund the provision of renal (10 cases), kidney papillary (3 cases), cervical (10 cases), | Health and Human Services, Department of / National Institutes of Health | 3/31/2010 |
| MOUNT SINAI SCHOOL OF MEDICINE | $32,430 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of the proposed research is to understand how a network of cyclindependent kinases (CDKs) and upstream CDK-activating kinases (CAKs) coordinates cell division with gene expression and the maintenance of genome integrity in a model eukar | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| CENTER ON ADDICTION & SUBSTANCE ABUSE AT COLUMBIA UNIVERSITY | $499,999 | Grant | Trans-NIH Recovery Act Research Support: Substance Use Disorders (SUD) are among the most prevalent and costly health conditions in the U.S. The current quality of care for SUD is mediocre, and profound changes must occur in state-level systems of care. Progress on solving systemic problems in S | Health and Human Services, Department of / National Institutes of Health | 1/11/2010 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $2,213,935 | Grant | Trans-NIH Recovery Act Research Support: Primary open angle glaucoma (POAG) is the most common form of glaucoma in the United States and a leading cause of irreversible blindness and visual impairment worldwide, affecting more than 2 million Americans over age 40, and causing blindness in ~100,0 | Health and Human Services, Department of / National Institutes of Health | 2/01/2010 |
| THE VANDERBILT UNIVERSITY | $85,075 | Grant | Trans-NIH Recovery Act Research Support: The major goal is to elucidate the structural and functional mechanisms by which the thalamus controls cortical processing in the primate brain. Our specific thesis for this proposal is that all thalamic nuclei contain some cell groups that act as driver | Health and Human Services, Department of / National Institutes of Health | 3/22/2010 |
| CASE WESTERN RESERVE UNIVERSITY | $383,232 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this application is to understand biochemical mechanisms that underlie the function of rhesus monkey TRIM5 (rhTRIM5). rhTRIM5 blocks HIV-1 infection by acting at two or more post-entry stages. Importantly, rhTRIM5 E3 ubiquitin ligase a | Health and Human Services, Department of / National Institutes of Health | 1/19/2010 |
| WASHINGTON STATE UNIVERSITY | $99,995 | Grant | Trans-NIH Recovery Act Research Support: The main goals of this proposal are 1) to provide the fundamental knowledge required for understanding Cytochrome P450 mediated reaction mechanism with regards to rates, regioselectivity, and binding, and 2) to provide computational tools for predicting t | Health and Human Services, Department of / National Institutes of Health | 1/21/2010 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $776,222 | Grant | Trans-NIH Recovery Act Research Support: Nonalchoholic Steatohepatitis Clinical Research Network: NASH. The purpose of the requested supplement is to fund the Cytokine Multiplex Assay Substudy of the nonalcoholic steatohepatitis (NASH) clinical research network (CRN), that proposes to quantify p | Health and Human Services, Department of / National Institutes of Health | 2/17/2010 |
| CLAREMONT GRADUATE UNIVERSITY | $145,234 | Grant | Trans-NIH Recovery Act Research Support: Over 17% of U.S. adolescents are considered overweight. The proposed study will advance our understanding of the dynamic relationship of overweight status and psychosocial adjustment problems during the period of pubertal transition, which will have impor | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $99,000 | Grant | Trans-NIH Recovery Act Research Support: The principal goals for the 24-27 years update since July 2005 will now include: (A) development of an enantioselective total synthesis of the potent insecticidal agent (+)-nodulisporic acid A, (B) completion of the total synthesis of the challenging macr | Health and Human Services, Department of / National Institutes of Health | 1/22/2010 |
| UNIVERSITY OF WASHINGTON | $99,998 | Grant | Trans-NIH Recovery Act Research Support: In funded work from the parent grant, we have cataloged somatic mutations altering the length of polyguanine tracts in order to infer developmental relationships between parts of the liver and other variously sampled tissues from the mouse. This work nece | Health and Human Services, Department of / National Institutes of Health | 2/16/2010 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $215,751 | Grant | Trans-NIH Recovery Act Research Support: The long term objective of this project is to determine the functions of glial cells (Muller cells and astrocytes) in the mammalian retina. Preliminary studies from our laboratory show that light-evoked neuronal activity can induce calcium increases in re | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| LEICA MICROSYSTEMS INC | $37,852 | Contract | : EM AFS2-AUTOMATIC FREEZE SUBSTITUTION SYSTEM 16977101 | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| NEW YORK STRUCTURAL BIOLOGY CENTER, INC., THE | $1,968,422 | Grant | Trans-NIH Recovery Act Research Support: The awarded funds will be used to purchase a dual-beam scanning electron microscope (SEM) that will be added to the shared electron microscopy facility at the New York Structural Biology Center (NYSBC). NYSBC currently provides state-of-the-art instrumen | Health and Human Services, Department of / National Institutes of Health | 1/28/2010 |
| UNIVERSITY OF WISCONSIN SYSTEM | $99,266 | Grant | Trans-NIH Recovery Act Research Support: The R01 grant Transcriptional Control of Hemoglobin Synthesis (DK050107) has been funded continuously for 12 years, received excellent to outstanding scores for the initial submission and subsequent competing renewals, and I appreciate the NIH support for | Health and Human Services, Department of / National Institutes of Health | 1/18/2010 |
| FLORIDA STATE UNIVERSITY, THE | $101,703 | Grant | Trans-NIH Recovery Act Research Support: In the present application, I am requesting salary support to retain an exemplary Research Scientist, Dr. Yan Liu, in my lab. Dr. Liu has made significant contributions to the study of the neurobiology of social attachment. These contributions have been | Health and Human Services, Department of / National Institutes of Health | 3/24/2010 |
| TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | $420,366 | Grant | Trans-NIH Recovery Act Research Support: This award was made to support a project whereby the investigators plan to use synthetic genome technology to create a virulent version of a temperate bacterial virus that infects strains of Enterococcus faecalis. It is expected that such a deriviative o | Health and Human Services, Department of / National Institutes of Health | 3/19/2010 |
| SCRIPPS RESEARCH INSTITUTE, THE | $99,000 | Grant | Trans-NIH Recovery Act Research Support: Glucagon initiates the gluconeogenic program in hepatocytes by activating the cAMP signaling pathway, while insulin inhibits hepatic gluconeogenesis. A key regulator of this process is TORC2 (also known as CRTC2), which functions as a molecular switch in | Health and Human Services, Department of / National Institutes of Health | 2/19/2010 |
| JOSLIN DIABETES CENTER, INC. | $88,930 | Grant | Trans-NIH Recovery Act Research Support: Role of IGF-1 and insulin receptors beta-cell survival - A paucity of functional ?-cells is a central feature of type 1 and type 2 diabetes and an urgent question in islet biology relates to plasticity of ?-cell mass in the long-term goal of developing st | Health and Human Services, Department of / National Institutes of Health | 3/15/2010 |
| DUKE UNIVERSITY | $87,430 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this administrative supplement request is to enhance our mouse model systemresearch into the mechanisms of craniofacial and foregut birth defects. Recent research from our ownlab and others has led to the surprising realization that the for | Health and Human Services, Department of / National Institutes of Health | 3/08/2010 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $154,586 | Grant | Trans-NIH Recovery Act Research Support: The goals of this application are to address the development of CD40+ T cells, the role that CD40 plays in T cell receptor (TCR) revision and how induced TCR revision impacts autoimmunity. CD40 has a direct role in autoimmune diseases including type 1 dia | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| UNIVERSITY OF FLORIDA | $14,682,885 | Grant | National Center for Research Resources, Recovery Act Construction Support: The state of Florida has the largest proportion (17.8%) of persons age 60 years or older in the nation and this age group represents the fastest growing segment of the population. In the 2000 US Census, more than 3.2 million F Floridians, or 22.2% of the st... Show more | Health and Human Services, Department of / National Institutes of Health | 1/13/2010 |
| MOREHOUSE SCHOOL OF MEDICINE, INC., THE | $9,850,883 | Grant | Trans-NIH Recovery Act Research Support: MSM has enjoyed much success in obtaining funds to purchase major shared instrumentation. The Core and Shared-Use facilities were built to relieve the burden of individual investigators attempting to purchase large pieces of equipment, and are available t | Health and Human Services, Department of / National Institutes of Health | 3/26/2010 |
| LOUVIERE, STRATTON & YOKEL, L.L.C. | $491,838 | Contract | : NIH American Recovery Reinvestment Act Reviews. | Health and Human Services, Department of / National Institutes of Health | 5/13/2009 |
| NORTHWESTERN UNIVERSITY | $119,903 | Grant | Trans-NIH Recovery Act Research Support: This is a proposal to acquire a state of the art Typhoon Fluoroimager/Phosphoimager as a shared instrument for the Northwestern University research community. This instrument provides versatile imaging capabilities and exceptional sensitivity for characte | Health and Human Services, Department of / National Institutes of Health | 2/20/2010 |
| UNIVERSITY OF ROCHESTER | $824,680 | Grant | Trans-NIH Recovery Act Research Support: We propose to acquire an 18-color, 5-laser BD Biosciences FACSAria-II cell sorter, with bio- containment hood and novel CellEvator acoustic wave powered sample mixer technology. This instrument will expand the availability of researchers to access cell so | Health and Human Services, Department of / National Institutes of Health | 1/07/2010 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $262,168 | Grant | Trans-NIH Recovery Act Research Support: Genetic epidemiologic design focusing on African Americans or Hispanics is particularly challenging because both groups have experienced recent admixture. Indeed, in the presence of cryptic population structure, case-control association designs can produc | Health and Human Services, Department of / National Institutes of Health | 1/15/2010 |
| CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE/CWRU | $500,000 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this proposal is to seek funds for the purchase of an LTQ OrbiTrap XL Mass Spectrometer. This instrument will expand and upgrade mass spectrometry capabilities within the Northeastern Ohio region, advancing research programs within the Clev | Health and Human Services, Department of / National Institutes of Health | 3/25/2010 |
| WASHINGTON STATE UNIVERSITY | $373,750 | Grant | Trans-NIH Recovery Act Research Support: Poor-quality sleep and sleep insufficiency are significant risk factors for physical and mental illness and are, thus, of major public-health concern. Obesity, diabetes and cardiovascular disease are all statistically linked to sleep insufficiency general | Health and Human Services, Department of / National Institutes of Health | 3/08/2010 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $44,850 | Grant | Trans-NIH Recovery Act Research Support: Examination of viral vectors to the neonatal mouse to examine for level of expression and immune consequences to lead to a better understanding of therapy that may be considered for human gene therapy. | Health and Human Services, Department of / National Institutes of Health | 1/27/2010 |
| THE VANDERBILT UNIVERSITY | $51,845 | Grant | Trans-NIH Recovery Act Research Support: This Recovery Act administrative supplement grant aims to continue and accelerate our research on structural requirements for sterol 14alpha-demethylase. Support for purchase of a new HPLC system is requested because the HPLC (1992) indicated in the equi | Health and Human Services, Department of / National Institutes of Health | 2/05/2010 |
| UNIVERSITY OF PITTSBURGH THE | $44,900 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplement is to buy an Isokinetic Dynamometer that will be used during implementation of the research proposed for the parent grant (Neuromuscular Electrical Stimulation in Individuals with Rheumatoid Arthritis- 1 KOI HD 058035 - 01 A | Health and Human Services, Department of / National Institutes of Health | 1/27/2010 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $190,520 | Grant | Trans-NIH Recovery Act Research Support: this supplement was to hire an additonal post-doctoral fellow to work on characterization of the methyl transfer reaction in the biosynthesis of thienamycin and to purchase additonal equipment to accelerate the pace of research for the parent grant. | Health and Human Services, Department of / National Institutes of Health | 3/29/2010 |
| UNIVERSITY OF WASHINGTON | $93,329 | Grant | Trans-NIH Recovery Act Research Support: One of the next great challenges in biology is to infer from the details of how networks of molecules interact within cells, to explanations of how cells behave, how they crawl, and divide or interact to decide what organ they'll become during development | Health and Human Services, Department of / National Institutes of Health | 2/19/2010 |
| UNIVERSITY OF FLORIDA | $99,987 | Grant | Trans-NIH Recovery Act Research Support: During the previous funding cycle we identified five monoclonal antibodies (MAbs) against the P1 surface adhesin of Streptococcus mutans that redirect the humoral immune response in mice in terms of quantity, specificity and isotype of elicited antibodies | Health and Human Services, Department of / National Institutes of Health | 3/08/2010 |
| UNIVERSITY OF MIAMI | $74,700 | Grant | Trans-NIH Recovery Act Research Support: Estrogen receptor-a (ER-a, hereon in, ER represents ER-a) and progesterone receptor (PR) are ligand-induced transcription factors. Accessory proteins, termed coactivators modulate the transcriptional activation of these factors. Coactivators in general ar | Health and Human Services, Department of / National Institutes of Health | 2/05/2010 |
| THE VANDERBILT UNIVERSITY | $499,901 | Grant | Trans-NIH Recovery Act Research Support: This supplement will be used to enhance the career development of our International Clinical Research Fellows through a competitive second year of employment, and to develop an online infrastructure of benefit to our current and future Fellows. We are re | Health and Human Services, Department of / National Institutes of Health | 1/22/2010 |
| AVANTBIO CORPORATION | $100,000 | Grant | Trans-NIH Recovery Act Research Support: Phase-1 Small Business Innovation Research (SBIR) grant award. SBIR funded research is designed to synthesize and test new drugs for the treatment of the commonly observed human inflammatory-proliferative skin diseases such as psoriasis and dermatitis. It | Health and Human Services, Department of / National Institutes of Health | 3/26/2010 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $140,680 | Grant | Trans-NIH Recovery Act Research Support: Social anxiety disorder (SAD) is among the most common psychiatric conditions and is associated with significant distress and dysfunction in affected individuals. Although treatment with cognitive-behavior therapy (CBT) results in some of the best outcome | Health and Human Services, Department of / National Institutes of Health | 3/12/2010 |
| SAIC FREDERICK, INC | $10,200,000 | Contract | : Phase I/II Clinical Trials and Pharmacodynamics NCIG??s Division of Cancer Treatment and Diagnosis (DCTD), under the umbrella of the American Recovery and Reinvestment Act of 2009 (ARRA), is requesting support for several new and expanded initiatives. The | Health and Human Services, Department of / National Institutes of Health | 2/04/2010 |
| BEVERLY C JOHNSON | $233,508 | Contract | : Acquisition support to the Office of Acquisition, Office of Research Facilities (ORF). | Health and Human Services, Department of / National Institutes of Health | 1/04/2010 |
| COY LABORATORY PRODUCTS, INC. | $10,671 | Contract | : Hypoxic Glove Box | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $50,000 | Grant | Trans-NIH Recovery Act Research Support: Inflammatory bowel diseases (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), are chronic and frequently disabling intestinal inflammatory disorders that affect more than a million individuals in the US. One of the most dreaded compl | Health and Human Services, Department of / National Institutes of Health | 3/12/2010 |
| WAYNE STATE UNIVERSITY (INC) | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The current application is for a supplement to the parent grant for equipment and personnel. Funds are requested to purchase new equipment and to replace aging equipment. This will not only improve the quality of research, but it will also increase work | Health and Human Services, Department of / National Institutes of Health | 2/01/2010 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $174,339 | Grant | Trans-NIH Recovery Act Research Support: This study will support the original grant Mechanism of Termination of DNA Replication, speed up goals that were already approved, and provide continued employment to postdoctoral fellows and a student. The additional work proposed, we believe is innova | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| UNIVERSITY OF MEDICINE AND DENTISTRY | $127,823 | Grant | Trans-NIH Recovery Act Research Support: This proposal will augment research on the Evolution of Genetic Regulatory Pathways now being funded by R01 GM085282. The purpose of both the original grant and the supplement is to use nematode genetics to elucidate how regulatory pathways change during | Health and Human Services, Department of / National Institutes of Health | 1/15/2010 |
| CURELINE, INC. | $263,417 | Contract | : Cureline, Inc. has been awarded a contract to provide tumor types to the NCI for The Cancer Genome Atlas (TCGA) project. Specifically this award is to fund the provision of tissue: breast ductal 50 cases, colon 30 cases, lung adeno 20 cases, lung squamou | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| UNIVERSITY OF TOLEDO, THE | $429,675 | Grant | Trans-NIH Recovery Act Research Support: We have two graduate students and an undergradute student (who worked in summer)supported by this grant who have initiated experiments to address the role of small RNAs in inducing apoptosis (Aim 1, Subaim 1.2.2) and pro-inflammatory cytokines (Aim 1, Su | Health and Human Services, Department of / National Institutes of Health | 2/18/2010 |
| NEW YORK UNIVERSITY (INC) | $114,075 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Autosomal-dominant polycystic kidney disease (ADPKD) is a common cause of end stage kidney disease. ADPKD is caused by mutations in one of two genes, PKD1 or PKD2, which are encoded by polycystin 1 (PC) and 2 respectiv | Health and Human Services, Department of / National Institutes of Health | 1/11/2010 |
| EMORY UNIVERSITY | $50,440 | Grant | Trans-NIH Recovery Act Research Support: The overall objective of the above proposal on which we base this administrative supplement is to characterize the role of metalloproteinase-9 (MMP-9) in intestinal epithelial cell differentiation and wound healing. The major GOAL of the Administrative Su | Health and Human Services, Department of / National Institutes of Health | 2/23/2010 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $61,600 | Grant | Trans-NIH Recovery Act Research Support: Adult to adult living donor liver transplantation (LDL T) was introduced in the United States in 1998 following its development in Asia. Surprisingly, the application of this approach to transplantation in the U.S. grew considerably, reaching approximatel | Health and Human Services, Department of / National Institutes of Health | 2/03/2010 |
| WASHINGTON UNIVERSITY, THE | $106,152 | Grant | Trans-NIH Recovery Act Research Support: As noted in our last progress report, groups of germ free mice have been colonized with four different communities of sequenced human gut symbionts and subsequently subjected to a combination of diet disturbances and invasions with other symbionts. We hav | Health and Human Services, Department of / National Institutes of Health | 1/26/2010 |
| UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE | $69,662 | Grant | Trans-NIH Recovery Act Research Support: The parent award is based on the hypothesis that PKA is activated specifically in the leading edge of migrating cells and this localized activity modulates key regulators of actin cytoskeletal dynamics and cell migration. The scope of the parent award is | Health and Human Services, Department of / National Institutes of Health | 1/14/2010 |
| DUKE UNIVERSITY | $114,846 | Grant | Trans-NIH Recovery Act Research Support: The Duke University Medical Center (DUMC) Clinical Trials Unit (CTU) proposes to address the key scientific areas of translational research and optimization of clinical management in children and adults, and prevention of mother to child transmission.The | Health and Human Services, Department of / National Institutes of Health | 2/26/2010 |
| BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | $112,739 | Grant | Trans-NIH Recovery Act Research Support: The maintenance of a stable phenotype requires a genome wide transcriptional oscillation with clusters of transcripts poised around the steady-state - this is the dynamic architecture of phenotype. We propose to demonstrate that changes in protein levels | Health and Human Services, Department of / National Institutes of Health | 2/05/2010 |
| UNIVERSITY OF WISCONSIN SYSTEM | $99,811 | Grant | Trans-NIH Recovery Act Research Support: To complete this randomized clinical trial featuring long-term epidemiologic study of children with cystic fibrosis (CF), we request supplementary funds to accelerate 2 of the 3 original specific aims and thereby ensure that we will accomplish in years 24 | Health and Human Services, Department of / National Institutes of Health | 12/28/2009 |
| MEDICAL COLLEGE OF WISCONSIN, INC., THE | $93,647 | Contract | : The Medical College of Wisconsin has been awarded a contract to provide tumor types to the NCI for the Cancer Genome Atlas project. Specifically this award is to fund the provision of 100 cervical cancer samples and 100 corresponding blood samples. Thes | Health and Human Services, Department of / National Institutes of Health | 3/10/2010 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $175,049 | Grant | Trans-NIH Recovery Act Research Support: We have recorded and analyzed data from a large group of neurons in the Abducens nucleus and compared the neuron-behavior correlations in different neuron types. | Health and Human Services, Department of / National Institutes of Health | 1/07/2010 |
| TRUSTEES OF INDIANA UNIVERSITY | $379,659 | Grant | Trans-NIH Recovery Act Research Support: Trisomy 21 results in phenotypes collectively referred to as Down syndrome (DS) including facial dysmorphology, a distinguishing feature of individuals with DS. The molecular and genetic etiology of DS phenotypes and how genes in three copies on human chr | Health and Human Services, Department of / National Institutes of Health | 3/08/2010 |
| WAYNE STATE UNIVERSITY (INC) | $15,000 | Grant | Trans-NIH Recovery Act Research Support: The objective of this supplement proposal is to mechanisticallycharacterize the Sac3 functionality in insulin-regulated glucose transport in fat and mucsle. Our central hypothesis is that Sac3 is a polyphosphoinositide phosphatase that negatively regulat | Health and Human Services, Department of / National Institutes of Health | 1/01/2010 |
| CASE WESTERN RESERVE UNIVERSITY | $56,900 | Grant | Trans-NIH Recovery Act Research Support: The central goal of insulin replacement therapy in the treatment of diabetes mellitus (DM) is tight control of blood glucose concentrations. Clinical trials, including the landmark Diabetes Control & Complications Trial (DCCT) and follow-up Epidemiology o | Health and Human Services, Department of / National Institutes of Health | 1/14/2010 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $135,529 | Grant | Trans-NIH Recovery Act Research Support: Nuclear receptors (NRs) and other DNA-binding transcription factors regulate transcription of their target genes by recruiting coregulator proteins to the promoter of the target genes. Many coregulators can assist NRs as either coactivators or corepressor | Health and Human Services, Department of / National Institutes of Health | 2/05/2010 |
| ALTRUM TECHNOLOGIES, INC | $147,410 | Grant | Trans-NIH Recovery Act Research Support: The endoscopy system and technology developed under this SBIR project will provide great benefit to GI patients by providing a low cost and minimally invasive method for early GI tract disease diagnosis and prevention. The proposed system provides an inno | Health and Human Services, Department of / National Institutes of Health | 3/26/2010 |
| WASHINGTON UNIVERSITY, THE | $150,000 | Grant | Trans-NIH Recovery Act Research Support: Children with liver disease present major challenges. These diseases are collectively important because of high morbidity, mortality, and public health impact. Management is often ineffective, with cirrhosis, liver failure and liver transplantation as com | Health and Human Services, Department of / National Institutes of Health | 1/31/2010 |
| UNIVERSITY OF FLORIDA | $1,524,000 | Grant | Trans-NIH Recovery Act Research Support: As life expectancy in the US continues to rise, the maintenance of independence among older Americans has emerged as a major clinical and public health priority. Efficient and reliable locomotion, or the ability to move without assistance, is a fundamenta | Health and Human Services, Department of / National Institutes of Health | 3/31/2010 |
| NEW YORK UNIVERSITY (INC) | $1,636,975 | Grant | Trans-NIH Recovery Act Research Support: Type III, or lambda, interferons (IFN) make up a newly discovered family of cytokines which, like the type I IFNs (alpha/beta), are induced by virus infection. IFN-lambda's signaling, through a unique receptor, leads to formation of the same interferon st | Health and Human Services, Department of / National Institutes of Health | 3/02/2010 |
| THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK INC | $49,035 | Grant | Trans-NIH Recovery Act Research Support: The supplement will support training in the social, cognitive and neural processes underlying personality disorders for Christopher Crew, an accomplished first year African American student in the Columbia University Psychology Ph.D. program. Crew's inter | Health and Human Services, Department of / National Institutes of Health | 3/24/2010 |
| UNIVERSITY OF WASHINGTON | $112,982 | Grant | Trans-NIH Recovery Act Research Support: Insulin like molecules alter system-wide protein turnover, yet the effects on individual proteins is unclear. A change in a protein's turnover can alter the stoichiometry of the active protein and ultimately affect the efficiency of a pathway. Additiona | Health and Human Services, Department of / National Institutes of Health | 2/05/2009 |
| MILTENYI BIOTEC INC | $6,966 | Contract | : gentleMACS Dissociator and MACSmix Tube Rotator | Health and Human Services, Department of / National Institutes of Health | 9/02/2009 |
| TEXAS A & M RESEARCH FOUNDATION | $48,500 | Grant | Trans-NIH Recovery Act Research Support: Many epidemiological and clinical studies have demonstrated that n-3 polyunsaturated fatty acids (PUPA), a bioactive food component, ameliorate immune-mediated inflammatory diseases. A primary effector molecule is thought to be docosahexaenoic acid (DHA, | Health and Human Services, Department of / National Institutes of Health | 1/19/2010 |
| UNIVERSITY OF KENTUCKY | $6,428,471 | Grant | Trans-NIH Recovery Act Research Support: The University of Kentucky (UK) requests $6,432,134 to renovate 5,526 sq. ft. on the fourth floor of the Sanders-Brown Center for Aging. The proposed renovation will completely demolish and remove the present aged and obsolete small barrier animal facilit | Health and Human Services, Department of / National Institutes of Health | 3/04/2010 |
| MILTENYI BIOTEC INC | $6,966 | Contract | : gentleMACS Dissociator and MACSmix tube Rotator | Health and Human Services, Department of / National Institutes of Health | 9/02/2009 |
| ARIZONA STATE UNIVERSITY | $164,500 | Grant | Trans-NIH Recovery Act Research Support: Our research in this project has focused on defining the changes in expression of nuclear encoded mitochondrial genes that predict changes in insulin sensitivity in skeletal muscle, with the goal of defining the molecular mechanisms underlying the connect | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $137,926 | Grant | Trans-NIH Recovery Act Research Support: The DNA polymerase III holoenzyme of E. coli is a prototypical replicative complex, exhibiting properties in common with other cellular replicases, including a high rate of processive elongation and the ability to interact with other proteins at the repli | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $110,244 | Grant | Trans-NIH Recovery Act Research Support: The adaptive immune system is founded on lymphocytes expressing a vast array of antigen receptors that provide specific recognition in responding to pathogen. Receptor diversity is generated by V(D)J rearrangement and, in immunoglobulin (Ig) genes, post-r | Health and Human Services, Department of / National Institutes of Health | 1/21/2010 |
| WASHINGTON METROPOLITAN AREA TRANSIT AUTHORITY | $0 | Contract | : These ARRA funds provided SmartBenefits on SmarTrip cards to NIH employees that they may use to ride MetroBus or MetroRail. The fare media may also be used on DASH, Ride On, Fairfax Connector, ART, CUE, Loudoun County Transit, Omniride, TheBus, DC Circula | Health and Human Services, Department of / National Institutes of Health | 6/30/2010 |
| PURDUE UNIVERSITY | $130,840 | Grant | Trans-NIH Recovery Act Research Support: The dynamic regulation of chromatin serves as an important mechanism for gene regulation. Many studies have demonstrated that posttranslational modification such as acetylation, phosphorylation, ubiquitination, and/or methylation of histones is a mechanis | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $174,005 | Grant | Trans-NIH Recovery Act Research Support: The insulin/IGF system evolved in metazoans to coordinate nutrient utilization with cell growth and proliferation, both in development and adult life. Control by the insulin/IGF system is superimposed upon and cross-regulated by phylogenetically older, nu | Health and Human Services, Department of / National Institutes of Health | 3/15/2010 |
| UNIVERSITY OF ILLINOIS | $2,931,085 | Grant | Trans-NIH Recovery Act Research Support: The University of Illinois at Chicago (UIC) requests grant support to purchase a state-of-the-art whole-body 3 Tesla (3T) magnetic resonance imaging (MRI) scanner to perform advanced anatomic, functional, spectroscopic and physiologic imaging for biomedic | Health and Human Services, Department of / National Institutes of Health | 2/18/2010 |
| UNIVERSITY OF CALIFORNIA, SANTA CRUZ | $110,140 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The complexity of human transcriptome is far greater than previously anticipated. Transcript diversity can be expanded through post-transcriptional RNA processing reactions as well as extensive inter-genic transcriptio | Health and Human Services, Department of / National Institutes of Health | 1/22/2010 |
| EMORY UNIVERSITY | $54,000 | Grant | Trans-NIH Recovery Act Research Support: REGULATION OF SODIUM CHLORIDE COTRANSPORTER BY WNK KINASE WNK (with no lysine (k)) is one of the new family of serine/thereonine kinases. Mutation in two members of this kinase, WNK1 and WNK4, causes pseudohypoaldosteronism type II (PHA II). The emerged e | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $99,258 | Grant | Trans-NIH Recovery Act Research Support: Obesity reflects excessive accumulation of long chain fatty acids (LCFA) as triglycerides in adipose and other tissues. We showed that cellular LCFA uptake is facilitated, and that its regulation in adipose tissue is a control point for adiposity. A detai | Health and Human Services, Department of / National Institutes of Health | 1/07/2010 |
| RADIOLOGICAL SOCIETY OF NORTH AMERICA, INC. | $4,697,377 | Contract | : The Contractor shall provide services to the National Institute of Biomedical Imaging and Bioengineering (NIBIB) in the design, development, and launch of an Internet-based network for patient-controlled medical image sharing built upon the Integrating th | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $113,326 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplement is to hire two additional personnel (1 postdoc and 1 graduate student) for the initial two years of the grant. Currently the initial 2 years of the grant support a full time technician (24 months), and two graduate students | Health and Human Services, Department of / National Institutes of Health | 3/05/2010 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $288,687 | Grant | Trans-NIH Recovery Act Research Support: Ocular immune privilege enables the eye to respond to antigenic challenges in ways that preserve the delicate structures of the eye. Although we and others have found active and passive mechanisms of immune privilege to retinal antigens, the details are | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| BAYLOR COLLEGE OF MEDICINE | $100,001 | Grant | Trans-NIH Recovery Act Research Support: Muscle wasting is a serious problem for patients with chronic kidney disease (CKD), occurring independently of dietary factors. Muscle protein losses are due to an increase in muscle protein degradation plus a smaller decrease in protein synthesis. We h | Health and Human Services, Department of / National Institutes of Health | 1/26/2010 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $9,526,509 | Grant | National Center for Research Resources, Recovery Act Construction Support: DESCRIPTION (provided by applicant): The Albert Einstein College of Medicine Strategic Research Plan established a Stem Cell Research Institute (SCRI) that will create cross-cutting opportunities in stem cell research and regegenerative medicine. Currently,... Show more | Health and Human Services, Department of / National Institutes of Health | 3/18/2010 |
| UNIVERSITY OF SOUTH FLORIDA | $100,000 | Grant | Trans-NIH Recovery Act Research Support: Alternative splicing of pre-mRNA transcripts is a widespread means for producing polypeptide diversity from a single gene. Over 60% of human genes are expressed through alternative splicing, however, mechanisms of splicing regulation are poorly understood | Health and Human Services, Department of / National Institutes of Health | 3/01/2010 |
| CHILDREN'S RESEARCH INSTITUTE | $118,161 | Grant | Trans-NIH Recovery Act Research Support: The supplemental project seeks to: 1) evaluate the impact of an ongoing RCT in a subgroup of parent/child dyads who are newly diagnosed with type 1 diabetes (T1D; childG??s diagnosis within the previous 6 months). The ongoing trial specifically limits rec | Health and Human Services, Department of / National Institutes of Health | 3/29/2010 |
| UNIVERSITY OF FLORIDA | $100,000 | Grant | Trans-NIH Recovery Act Research Support: Agouti-related protein (AGRP) and agouti (ASP) are the only two naturally occurring antagonists of G-protein coupled receptors (GPCRs) identified to date, and when over expressed in mice, result in an obese phenotype. Obesity (body mass index >25) afflict | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $84,036 | Grant | Trans-NIH Recovery Act Research Support: During the first meiotic division, homologous chromosomes linked by chiasmata interact with the spindle microtubules and segregate to opposite poles. Defects in this process lead to aneuploidy in the fertilized egg and have serious consequences on develop | Health and Human Services, Department of / National Institutes of Health | 2/12/2010 |
| COLORADO STATE UNIVERSITY | $6,063,912 | Grant | National Center for Research Resources, Recovery Act Construction Support: This proposal requests funds to complete construction of an Imaging Facility devoted to work with BSL- 3 pathogens and Select Agents and to provide an underground electrical feed to the Imaging Facility and the rest of the Infnfectious Disease Research Cent... Show more | Health and Human Services, Department of / National Institutes of Health | 3/25/2010 |
| CASE WESTERN RESERVE UNIVERSITY | $99,130 | Grant | Trans-NIH Recovery Act Research Support: Development in metazoans is regulated by specific regulatory hierarchies leading to the stage- and tissue-specific expression of transcriptional networks. Understanding such networks poses a major challenge in developmental biology. A model is provided by | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $91,100 | Grant | Trans-NIH Recovery Act Research Support: Our long term goal is to understand how genetic recombination contributes to the faithful inheritance of chromosomes. Genetic recombination is of central importance to sexually reproducing organisms, since crossover recombination events between the DNA mo | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| JOHNS HOPKINS UNIVERSITY, THE | $34,980 | Grant | Trans-NIH Recovery Act Research Support: The hypothalamus plays a central role in maintaining energy homeostasis. Within the hypothalamus, different nuclei have been shown to play distinct roles in controlling food intake and energy expenditure. Although a role for the dorsomedial hypothalamus ( | Health and Human Services, Department of / National Institutes of Health | 2/26/2010 |
| BROWN UNIVERSITY IN PROVIDENCE IN STATE OF RI AND PROVIDENCE PLANTATIONS | $499,800 | Grant | Trans-NIH Recovery Act Research Support: Brown has almost 600 faculty/researchers in the Division of Biology and Medicine; it received $112,884,965 in NIH support in 2008, it has a strong translational and clinical research group, and a basic research emphasis on genomic applications. Yet this i | Health and Human Services, Department of / National Institutes of Health | 3/12/2010 |
| MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY | $29,975 | Grant | Trans-NIH Recovery Act Research Support: Autoimmune thyroid diseases (AITD) are highly prevalent. Abundant data demonstrate a major role for genetic factors in the pathogenesis of AITD. Recently, we and others have demonstrated that the presence of arginine at position 74 of the HLA-DR31 chain ( | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | $11,851,780 | Grant | National Center for Research Resources, Recovery Act Construction Support: This grant will support the construction of a contiguous research facility on the 8th and 9th floors of the new Temple University School of Medicine building which is currently unoccupied 'shelled' space. The facility will hououse the new Temple Institute f... Show more | Health and Human Services, Department of / National Institutes of Health | 3/04/2010 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $54,000 | Grant | Trans-NIH Recovery Act Research Support: This applicant proposes a program to prepare him for a career in academic basic science studying renal function, addressing the regulation of proton secretion in the kidney under physiological and patho- physiological conditions. The research will be cond | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| DUKE UNIVERSITY | $108,000 | Grant | Trans-NIH Recovery Act Research Support: Described below is an administrative supplemental request for an actively funded K08 grant entitled Non Muscle Myosin II Contractility Putatively Regulates Scar Contracture. This proposal has been devised based on the goals of the NIGMS-Specific Requireme | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF IOWA, THE | $86,945 | Grant | Trans-NIH Recovery Act Research Support: Over the last decade, the prescribing rate of atypical antipsychotics (AAPs) for youth has increased by several folds. This has resulted in a striking contrast between the use of AAPs and the limited scientific evidence regarding their efficacy and safety | Health and Human Services, Department of / National Institutes of Health | 3/15/2010 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $75,620 | Grant | Trans-NIH Recovery Act Research Support: Pancreatitis is an inflammatory disease of the pancreas. Every year, over 225,000 patients are diagnosed with pancreatitis and over two billion dollars are spent on their care. However, there is currently no treatment for these patients besides conservati | Health and Human Services, Department of / National Institutes of Health | 1/31/2010 |
| CREIGHTON UNIVERSITY | $143,104 | Grant | Trans-NIH Recovery Act Research Support: The ARRA funded project is in response to PAR-09-028, Shared Instrumentation Grant Program, and requests a GE Healthcare Typhoon 9410 Workstation. The acquisition of the Typhoon 9410 will enhance ongoing NIH funded research in areas such as prion pathoge | Health and Human Services, Department of / National Institutes of Health | 3/18/2010 |
| EAST CAROLINA UNIVERSITY | $40,602 | Grant | Trans-NIH Recovery Act Research Support: The administrative supplement provided funding for the purchase of a high resolution O2K respirometer (Oroboros, Inc). This machine measures the rate of oxygen consumption in cells and tissues under very controlled conditions. Specifically, the ongoing | Health and Human Services, Department of / National Institutes of Health | 2/01/2010 |
| TRUSTEES OF INDIANA UNIVERSITY | $84,372 | Grant | Trans-NIH Recovery Act Research Support: This proposal was for the purchase of a Bio-Rad Bio-Plex 200 Multiplex Array System with high throughput fluidics. The Bio-Plex will be used for basic and translational research in the Departments of Medicine, Pathology, Pediatrics, and Microbiology/Immun | Health and Human Services, Department of / National Institutes of Health | 3/25/2010 |
| RANGER GROUP LLC, THE | $3,037,931 | Contract | : Recovery Act -- Repair & Upgrade Switchgear -- Building 21 | Health and Human Services, Department of / National Institutes of Health | 3/09/2010 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $98,500 | Grant | Trans-NIH Recovery Act Research Support: In this ARRA administrative supplement application, we propose to carry out aims of the parent grant (RO1 DK080996 ?Role of polycomb group gene Bmi-1 in beta cell regeneration and aging ?) to examine the mechanism by which the polycomb genes are removed | Health and Human Services, Department of / National Institutes of Health | 1/28/2010 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $80,000 | Grant | Trans-NIH Recovery Act Research Support: This research aims to elucidate reaction intermediates of NO-reductase activity in diiron proteins, with the ultimate goal of understanding how the metal clusters catalyze this reaction. Our studies will focus on three emzymes: 1) denitrifying NO reducta | Health and Human Services, Department of / National Institutes of Health | 3/05/2010 |
| NORTH CAROLINA STATE UNIVERSITY | $142,739 | Grant | Trans-NIH Recovery Act Research Support: The zebrafish (Danio rerio) has become a powerful model for investigating the genetics of human disease and development; however, currently no generally applicable tools for dissecting embryonic gene function in a switchable, spatio-temporal manner exist. | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| WASHINGTON UNIVERSITY, THE | $327,585 | Grant | Trans-NIH Recovery Act Research Support: Small laboratory animal models such as mice, rats and hamsters are widely used throughout the biomedical research community at Washington University in St. Louis and other scientific institutions. With the recent revolution in molecular biology, transgeni | Health and Human Services, Department of / National Institutes of Health | 1/28/2010 |
| DUKE UNIVERSITY | $14,916,552 | Grant | National Center for Research Resources, Recovery Act Construction Support: Duke researchers whose current or past investigations have required significant use of USDA-covered species are responsible for $20,407,773 in annual direct costs from the National Institutes of Health. Strength of these progrgrams is projected to double th... Show more | Health and Human Services, Department of / National Institutes of Health | 3/04/2010 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $175,750 | Grant | Trans-NIH Recovery Act Research Support: The goal of our application is to obtain a Heidelberg Spectralis OCT instrument for research at Columbia University's Harkness Eye Institute. The many faculty members here who are conducting research on retinal degenerative disorders rely on the latest im | Health and Human Services, Department of / National Institutes of Health | 3/04/2010 |