Primary Recipient

WAYNE STATE UNIVERSITY (INC)

Amount

$759,997.00

Award Date

9/21/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

The specific aims are: 1) To establish the mechanism(s) of insulin activation of Akt on CYP2E1 gene transcription; 2) To examine the mechanism(s) by which insulin activation of mTOR regulates CYP2E1 mRNA translation and miRNA translation repression of deg