Primary Recipient

THE VANDERBILT UNIVERSITY

Amount

$332,016.00

Award Date

9/18/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

EGF receptor (EGFR) ligands are produced as type 1 transmembrane proteins that are cleaved from the cell surface to produce soluble ligand. EGFR activation can be achieved by soluble ligand (autocrine or paracrine) or by membrane-tethered ligand (juxtacri