Grant: CHILDREN'S RESEARCH INSTITUTE
Primary Recipient
CHILDREN'S RESEARCH INSTITUTE
Amount
$558,800.00
Award Date
9/15/2009
Administering Agency
Health and Human Services, Department of / National Institutes of Health
CDFA Number
93.701
CDFA Program Title
Trans-NIH Recovery Act Research Support
Description
The goal of this project is to produce a murine model for neonatal onset N-acetyl-L-glutamate synthase (NAGS) deficiency by creating a mouse in which the NAGS gene has been disrupted. Defects in urea cycle genes such as NAGS affect approximately one in 16