Primary Recipient

DUKE UNIVERSITY

Amount

$780,000.00

Award Date

9/09/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

Understanding the mechanisms of limbic epileptogenesis may lead to novel disease modifying therapies. We have discovered that epileptogenesis is associated with enhanced activation of TrkB in the mossy fiber pathway of hippocampus. We have also discovered