Primary Recipient

MASSACHUSETTS INSTITUTE OF TECHNOLOGY

Amount

$419,265.00

Award Date

5/15/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

Tau is a natively unfolded protein that has been implicated in the pathogenesis of several neurodegenerative disorders such as Alzheimer's disease (AD). A number of studies suggest that aggregates of tau contribute to neuronal death and dysfunction in AD