Primary Recipient

JOHNS HOPKINS UNIVERSITY, THE

Amount

$189,000.00

Award Date

9/04/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

Molecular Genetic Analysis of Colorectal Cancer: Activation due to phospho-peptide binding To fully elucidate the activation mechanism of the oncogenic mutations of PI3K? we designed mutants at the interfaces of the SH2 domains (both nSH2 and cSH2) with t