Primary Recipient

WHITEHEAD INSTITUTE FOR BIO-MEDICAL RESEARCH

Amount

$556,963.00

Award Date

9/09/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

BRCA1 mutations trigger high penetrance breast carcinogenesis. Most such tumors are triple negative/basal-like. How loss of BRCA1 function elicits breast cancer development and why it does so at markedly high rates and, often, at abnormally young ages is