Primary Recipient

DUKE UNIVERSITY

Amount

$614,162.00

Award Date

7/22/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

The murine antibody repertoire experiences a series of expansions and contractions that coincide with specific stages of B-cell development and differentiation. The initial repertoire of antibody specificities generated by V(D)J recombination is reduced d