Primary Recipient

THE INSTITUTE FOR CANCER RESEARCH

Amount

$787,981.00

Award Date

7/17/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

Abstract: The objective of this proposal is to understand the mechanism for the 5G?? strand-specific end processing of DNA double-strand breaks (DSBs) in eukaryotes. DSBs are among the most deleterious types of DNA damages. If not properly repaired, DSBs