Primary Recipient

WAYNE STATE UNIVERSITY (INC)

Amount

$760,000.00

Award Date

7/15/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

The goal of this award is to generate an inducible knockin mouse targeting the Plp1 gene on the X-chromosome. Mutations in the PLP1 gene cause Pelizaeus-Merzbacker disease, and we have determined that a major in the pathophysiology is a protein traffickin