Primary Recipient

UNIVERSITY OF CHICAGO, THE

Amount

$153,583.00

Award Date

9/18/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

Cerebral deposition of ?-amyloid peptides (A?) is one of the pathological hallmarks of AlzheimerG??s disease. A? is generated by sequential proteolysis of amyloid precursor protein (APP) by BACE1 and ?-secretase. ?-secretase is a multimeric protein comple