Primary Recipient

RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE

Amount

$143,372.00

Award Date

9/30/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

Myotonic muscular dystrophy type 1 (DM1) and type 2 (DM2) are caused by a toxic gain of function by expanded repeating RNAs. Both expanded repeats reside in noncoding regions and bind to the splicing regulator muscleblind (MBNL1); the formation of the RNA