Primary Recipient

THOMAS JEFFERSON UNIVERSITY

Amount

$193,125.00

Award Date

9/24/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

Our Preliminary Data show that hypertrophic chondrocytes do in fact express CHOP, an important UPR target protein that has a prominent role in ER stress-induced apoptosis. We found also that pre-hypertrophic chondrocytes express Bip, a chaperon protein th