Primary Recipient

TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA

Amount

$359,936.00

Award Date

9/28/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

Thyroid hormone receptors (TRs) are ligand dependent, transcriptional regulators of metabolism. TRs repress gene expression in the absence of hormone, which is paradigmatic for other nuclear receptors (NRs) that function as repressors in the unliganded st