Primary Recipient

TEMPLE UNIVERSITY

Amount

$98,325.00

Award Date

9/03/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

BCR/ABL fusion tyrosine kinase transforms HSC causing chronic myelogenous leukemia in chronic phase (CML-CP). BCR/ABL modulates the response to ?spontaneous? DNA damage to promote genomic instability. The latter may lead to resistance to tyrosine kinase i