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Grant: UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS

Primary Recipient

UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS

Amount

$247,275.00

Award Date

9/25/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

We propose to study chimeras of MscL orthologues with distinct functional characterists. In addition, we propose to define potential changes in protein-lipid (or other hydrophobic) interactions that occur upon MscL gating by screening a cysteine library