Primary Recipient

UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS

Amount

$280,869.00

Award Date

8/13/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

Malfunction of the spindle checkpoint has been implicated in human cancers. The class of antimitotic anti-cancer drugs, such as Taxol, kills cancer cells by exploiting defects in this pathway. The proposed experiments will shed light on the molecular ba