Primary Recipient

UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL

Amount

$591,993.00

Award Date

9/29/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

Alpha-1 antitrypsin (AAT) deficiency, due to the ?PiZZ? mutation, results in life-threatening lung and liver diseases in children and adults. Fortunately, the lung disease can be prevented by gene addition therapy. However, this strategy could not halt li