Primary Recipient

FRED HUTCHINSON CANCER RESEARCH CENTER

Amount

$136,565.00

Award Date

9/15/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

The Fbw7 ubiquitin ligase is central to the negative regulation of a number of growth promoting proteins. A central goal of my K08 proposal is to utilize mouse models to understand how loss of Fbw7 contributes to colorectal tumorigenesis in vivo. As the u