Primary Recipient

UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH

Amount

$216,600.00

Award Date

9/29/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

The modulation of 4-HNE and its glutathione conjugate levels in lung cancer cells through inhibition of its metabolism and disposition can optimize the cancer cell killing by activation of both Fas and p53-mediated apoptotic signaling. These studies will