Primary Recipient

THOMAS JEFFERSON UNIVERSITY

Amount

$849,750.00

Award Date

8/04/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

In the previous funding cycle, we have found that EAAT2 is selectively cleaved by caspase-3 in the spinal cord of mutant SOD1 (SOD1-G93A) transgenic mice model of ALS and that the C-terminal EAAT2 fragment derived from this cleavage (termed CTE fragment)