Primary Recipient

UNIVERSITY OF PITTSBURGH THE

Amount

$623,500.00

Award Date

5/05/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

Cross-regulation of apoptosis and autophagy as a molecular basis for reversal of tumor TRAIL resistance. Defects in apoptotic capability that evolve during tumorigenesis promote tumor growth, provide survival advantage, and confound treatment. Such defec