Primary Recipient

UNIVERSITY OF PITTSBURGH THE

Amount

$413,535.00

Award Date

6/04/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

This study is aimed to elucidate the significant effect and the mechanisms of RNA editing enzyme ADAR1 (Adenosine Deaminase Acting on RNA -1). ADAR1 is an essential protein required for cell survival and embryonic development. Knockout of the gene en