Primary Recipient

TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA

Amount

$123,666.00

Award Date

9/04/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

The proposed studies examine mechanisms by which aging impairs wakefulness. First, we propose using a recently described novel technique that utilizes a tagged unfolded protein sensor to quantitatively measure misfolded proteins (Wen and Glenn, Molecular