Primary Recipient

CHILDREN'S HOSPITAL MEDICAL CENTER

Amount

$213,217.00

Award Date

7/30/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

Chronic myelogenous leukemia (CML) is a clonal myeloproliferative disease with deregulated expression of the fusion gene p210-BCR-ABL. Molecular targeting of p210-BCR-ABL by inhibiting the abl kinase activity with Imatinib or other agents can suppress gro