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Grant: RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE

Primary Recipient

RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE

Amount

$706,500.00

Award Date

7/16/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

Numerous studies have shown that the protein tyrosine phosphatase SHP-1 modulates the expression of proinflammatory genes in leukocytes and glia that have been shown to cause inflammatory demyelination in the CNS. Accordingly, genetic deficiency in SHP-1