Primary Recipient

CHILDRENS HOSPITAL OF PHILADELPHIA

Amount

$420,000.00

Award Date

8/01/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

Most strategies to increase marrow production of platelets have focused on use of positive cytokines such as thrombopoietin (TPO). We have recently described an important inhibitory loop that also regulates platelet counts. We found that at least one chem