Primary Recipient

SCRIPPS RESEARCH INSTITUTE, THE

Amount

$107,673.00

Award Date

1/21/2010

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

The goal of this project is to determine the catalytic mechanism of the glmS ribozyme, which is an important RNA enzyme that regulates bacterial metabolism. The approach is to use 8-azapurine fluorescence to monitor the protonation states of G33, an essen