Primary Recipient

UNIVERSITY OF NEBRASKA

Amount

$60,000.00

Award Date

1/04/2010

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

Project summary: Holocarboxylase synthetase (HCS) plays a crucial role in the regulation of the binding of the vitamin biotin to histones in humans and other animals. Decreased biotinylation of histones in biotin-deficient human cells and animal models c