Primary Recipient

REGENTS OF THE UNIVERSITY OF MINNESOTA

Amount

$415,250.00

Award Date

7/17/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

Smad3 plays a central role in the TGF?-mediated fibrosis with characteristic inflammation, proliferation and transformation of fibroblasts and epithelial-to- mesenchymal transition. Gene therapy and small chemicals targeting Smad3 signaling have shown gre