Primary Recipient

JOHNS HOPKINS UNIVERSITY, THE

Amount

$807,497.00

Award Date

5/07/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

This project is to investigate the mechanism of activation of the interferon regulatory factor (particularly IRF-3) following virus infection.-? The activation of IRFs, which is triggered by the phosphorylation of certain Ser/Thr residues, results in its