Primary Recipient

UNIVERSITY OF CALIFORNIA, SAN DIEGO

Amount

$100,000.00

Award Date

2/01/2010

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

Central goal is to elucidate the role of a MAP3K known as MLK3 (mixed lineage kinase-3) in inducing beta cell death. The rationale behind our studies is the demonstration that both cytokines and lipids, like ceramide, act as specific agonists of MLK3, su