Primary Recipient

SCRIPPS RESEARCH INSTITUTE, THE

Amount

$755,320.00

Award Date

8/01/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

This project will focus on the discovery of compounds that act as potent Inhibitors of each of the six ATPases In the proteasome. These proteins use the energy of ATP hydrolysis to unfold proteins destined for degradation by the proteasome and feed them I