Primary Recipient

CHILDREN'S HOSPITAL MEDICAL CENTER

Amount

$101,500.00

Award Date

3/17/2010

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

1. Evaluating the hypothesis that selected GCase-competitive inhibitors can act as pharmacological chaperones in vivo and can correct abnormal GCase function and glucosylceramide (GC) accumulation in visceral organs. These in vivo investigations will test