Primary Recipient

UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO

Amount

$353,176.00

Award Date

7/09/2010

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

TRIM5alpha proteins bind retroviral capsids after cell entry and restrict retroviral infection by blocking reverse transcription and/or integration of the viral genetic material {Nisole, 2005 #305; Towers, 2007 #310}. This novel mechanism of cellular immu