Primary Recipient

UNIVERSITY OF CINCINNATI

Amount

$706,500.00

Award Date

9/01/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

Pertussis toxin (PTX) is a complex AB5 toxin, comprised of the enzymatically active, 'A' subunit (S1), and the binding, 'B' oligomer (PTX-B), composed of five subunits S2, S3, S4, and S5, found in a 1:1:2:1 ratio. The B portions of AB toxins transport the