How We Compiled Our Data. Visit our Eye on the Stimulus blog. Data current as of March 2010.
Erie County, N.Y.| U.S. | New York | Erie | ||
|---|---|---|---|---|
| Population | 304,059,724 | 19,490,297 | 909,845 | |
| Total recovery funding | $312,735,579,044 | $22,244,669,208 | $441,059,341 | |
| Direct to County | $290,999,413,356 | $20,310,238,241 | $441,059,341 | |
| County Funds per Capita | $957 | $1,042 | $485 | |
| Unemployment (12/08) |
7.4 | 6.6 | 6.8 | |
| Unemployment (12/09) |
10 | 9.0 | 8.3 | |
| Median Household Income | $50,007 | $52,944 | $44,650 | |
| Poverty Rate | 13.3% | 14.0% | 13.9% |
Show more/fewer agencies
Stimulus contracts, grants and loans in Erie County, N.Y.
Data last updated on March 2010.
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Note: County-level data does not include tax cuts, Medicaid, unemployment benefits or food stamps. There still may be overrepresentation of money going to counties where capitals are located because in some cases, awards to state agencies did not indicate that they were to be used statewide.
This county has more than 300 stimulus spending items. View the top 300 items by expenditure amount. View the lists by federal department and agency in the top-right corner of this page.
Amount refers to both the amount of stimulus funding going toward the project and the face value of the loan.
| Recipient | Amount | Type | Description | Federal Dept./Agency | Date | ||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| NIAGARA FRONTIER TRANSPORTATION AUTHORITY | $24,430,788.00 | Grant |
Federal Transit_Formula Grants The purpose of this grant is to invest in public transportation by purchasing new transit buses. Project NY-96-X017-00 entails the procurement of fifty-six (56) new diesel buses which will replace a like amount of life expired 40-foot diesel buses. The buses will operatte in daily transit service throughout Niagara Frontier Transportation Authority?s (NFTA) 1,575 square mile service area of Erie and Niagara Counties in New York State.... Show more
This spending item is part of a $24,430,800.00 allocation. See details |
Transportation Department / Federal Transit Administration | 8/21/2009 | ||||||||||||||||||||||||
| BUFFALO SEWER AUTHORITY | $17,777,801.00 | Grant |
Capitalization Grants for Clean Water State Revolving Funds The award provides funding under the American Recovery and Reinvestment Act of 2009 to the State of New York to capitalize its revolving loan fund for the financing for the construction of wastewater treatment facilities and associated infraastructure, green infrastructure, nonpoint source projects, estuary projects and program administration. The primary purposes of the award are to: preserve and create jobs and promote economic recovery through the investment in infrastructure protects that will improve water quality and will provide long-term economic benefits.... Show more
This spending item is part of a $432,564,000.00 allocation. See details |
Environmental Protection Agency | 4/02/2009 | ||||||||||||||||||||||||
| Cash for Clunkers Participants | $15,341,000.00 | Grant |
Only the top 10 dealers shown. See all 71 Note: Though Cash for Clunkers was not part of the original stimulus bill, $2 billion in stimulus funds were used to extend the program. |
Transportation Department / National Highway Traffic Safety Administration | |||||||||||||||||||||||||
| BUFFALO MUNICIPAL HOUSING AUTHORITY INC | $14,510,364.00 | Grant | Public Housing Capital Fund Stimulus (Formula) Recovery Act Funded Capital Fund Program ARRA formula grant | Housing and Urban Development Department | 6/02/2009 | ||||||||||||||||||||||||
| BUFFALO CITY SCHOOL DISTRICT | $14,030,402.00 | Grant |
State Fiscal Stabilization Fund (SFSF) - Education State Grants, Recovery Act For the support of public elementary, secondary, and post secondary education and, as, applicable early childhood education programs and services
This spending item is part of a $1,653,930,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 5/08/2009 | ||||||||||||||||||||||||
| BRYANT & STRATTON COLLEGE INC | $10,395,664.00 | Grant | Federal Pell Grant Program GRANT PROGRAM | Education Department / DOED - Student Financial Assistance Programs | |||||||||||||||||||||||||
| D.V. Brown & Associates, Inc. | $8,674,000.00 | Contract | Provide all labor, materials , tools and equipment necessary for our project at the VA Western New York Healthcare System, Buffalo NY. | Department of Veterans Affairs | 5/13/2009 | ||||||||||||||||||||||||
| BUFFALO SEWER AUTHORITY | $8,633,900.00 | Grant |
Capitalization Grants for Clean Water State Revolving Funds The award provides funding under the American Recovery and Reinvestment Act of 2009 to the State of New York to capitalize its revolving loan fund for the financing for the construction of wastewater treatment facilities and associated infraastructure, green infrastructure, nonpoint source projects, estuary projects and program administration. The primary purposes of the award are to: preserve and create jobs and promote economic recovery through the investment in infrastructure protects that will improve water quality and will provide long-term economic benefits.... Show more
This spending item is part of a $432,564,000.00 allocation. See details |
Environmental Protection Agency | 4/02/2009 | ||||||||||||||||||||||||
| NEIGHBORHOOD HOUSING SERVICES OF SOUTH BUFFALO, INC. | $8,344,996.00 | Grant |
Weatherization Assistance for Low-Income Persons Weatherization formula grants allocated to the New York State Division of Housing and Community Renewal (DHCR) under the American Recovery and Reinvestment Act (ARRA). Funds are provided to reduce the energy expenditures of low-income households by coonducted instrumented energy audits and installing energy conservation materials such as insulation, weatherstripping and caulk, high-efficiency heating and hot water systems, high-efficiency electrical fixtures and efficient building materials such as windows and doors. Award amount includes administrative funding (up to 5%) that will be retained by DHCR for administration. Funds are allocated to eligible subrecipients throughout the state who are responsible for proper installation, compliance with program rules and quality assurance. ARRA funds are expected to provide energy conservation assistance for more than 45,000 dwelling units.... Show more
This spending item is part of a $394,687,000.00 allocation. See details |
Energy Department | 4/01/2009 | ||||||||||||||||||||||||
| SUPPORTIVE SERVICES CORP | $8,124,093.00 | Grant |
Weatherization Assistance for Low-Income Persons Weatherization formula grants allocated to the New York State Division of Housing and Community Renewal (DHCR) under the American Recovery and Reinvestment Act (ARRA). Funds are provided to reduce the energy expenditures of low-income households by coonducted instrumented energy audits and installing energy conservation materials such as insulation, weatherstripping and caulk, high-efficiency heating and hot water systems, high-efficiency electrical fixtures and efficient building materials such as windows and doors. Award amount includes administrative funding (up to 5%) that will be retained by DHCR for administration. Funds are allocated to eligible subrecipients throughout the state who are responsible for proper installation, compliance with program rules and quality assurance. ARRA funds are expected to provide energy conservation assistance for more than 45,000 dwelling units.... Show more
This spending item is part of a $394,687,000.00 allocation. See details |
Energy Department | 4/01/2009 | ||||||||||||||||||||||||
| DEMCO, INC. | $6,633,145.00 | Contract |
Project Value: 2002070: Recovery Act Project Description of Work: RA-09-001 1. Installation of two groundwater characterization/monitoring wells (one well in FY 2009 and one in FY2011) in Pahute Mesa for the Underground Test Area (UGTA) project. The 2009 well will require an offset due to down-holee field conditions. 2. Provide labor, materials, and equipment to complete demolition of the Pluto Disassembly Facility; the Reactor Maintenance, Assembly, and Disassembly (RMAD) Facility; and two ancillary structures (i.e. furnace piping and a moveable shed (Building 3211) associated with the Test Cell C Facility. 3. Conduct characterization support for the Corrective Action Investigation Plans and Corrective Action Decision Documents at Soils Corrective Action Units 106, 367, 374, and 375. 4. Provide support for remediation activities at Industrial Sites Corrective Action Unit 408. RA-10-001 Maintain the capability to safely and compliantly receive and dispose 2M ft3 of Low-Level Waste (LLW) and Mixed LLW at the Area 5 Radioactive Waste Management Site in support of the U.S. Department of Energy Complex (DOE) in Fiscal year 2010. Work authorization was awarded on 12/17/09 with a definitization completion date of 2/5/10.... Show more
This spending item is part of a $38,550,400.00 allocation. See details |
Energy Department / Office of Nuclear Security/National Nuclear Security Administration | 6/04/2009 | ||||||||||||||||||||||||
| ERIE COMMUNITY COLLEGE | $6,458,611.00 | Grant | Federal Pell Grant Program GRANT PROGRAM | Education Department / DOED - Student Financial Assistance Programs | |||||||||||||||||||||||||
| BUFFALO CITY SCHOOL DISTRICT | $6,018,639.00 | Grant |
Special Education Grants to States, Recovery Act Assist States in providing special education and related services to children with disabilities in accordance with Part B of the IDEA
This spending item is part of a $759,193,000.00 allocation. See details |
Education Department / Office of Special Education and Rehabilitative Services | 4/01/2009 | ||||||||||||||||||||||||
| ERIE, COUNTY OF | $5,928,603.90 | Grant |
Highway Planning and Construction Highway Infrastructure Investment Grant: Available for Use in Any Area (flexible)
This spending item is part of a $7,000,000.00 allocation. See details |
Transportation Department / Federal Highway Administration | 4/29/2009 | ||||||||||||||||||||||||
| HARBORVIEW PRESERVATION, LP | $4,770,000.00 | Grant |
Tax Credit Assistance Program (Recovery Act Funded) Tax Credit Assistance Program provides funding assistance for affordable rental housing projects that have been allocated Low-Income Housing Tax Credit and need additional equity.
This spending item is part of a $252,660,000.00 allocation. See details |
Housing and Urban Development Department | 6/19/2009 | ||||||||||||||||||||||||
| HEALTH RESEARCH, INC. | $4,675,896.00 | Grant | National Center for Research Resources, Recovery Act Construction Support This NTH construction application is requesting $2,401,705 to renovate the third and three-quarters of the fourth floor (20,763 net sq. ft) in the 30-year-old, 5-story Cancer Cell Center building (CCC) at Roswell Park Cancer Innstitute (RPCI) for occupancy by the Tumor Immunotherapy Program. The CCC located on RPCI's campus is interconnected with Cancer Genetics and Pharmacology in the new Buffalo Life Science Complex (June '06 completion) and the Departments of Molecular Biology and Biophysics. Also, the CCC will connect to the Hauptman Woodward Institute (HWI) housing the Center for Structural Biology and Crystallography (March '05 occupancy) and the University of Buffalo Center of Bioinformatics (June '06 completion). Thus, the assembled Immunotherapy Program located within the proposed renovated space within the CCC will provide an outstanding opportunity for closer scientific and clinical interactions with other programs at RPCI resulting in enhanced translational research opportunities. The proposed renovation within the Department of Immunology at RPCI will house eight peer-reviewed funded investigators and one additional senior faculty member under recruitment with a common research focus aimed at the identification of immunological markers for the development of selective immunotherapy for cancer patients. This request is a critical component of the overall strategic plan of the Immunology Department and the Institute. The faculty members to be housed in the renovated space are presently located in several different buildings with outdated laboratories. Thus, the proposed renovation is not only critical for enhancement of ongoing basic and translational research but for the recruitment and retention of faculty.... Show more | Health and Human Services, Department of / National Institutes of Health | 10/20/2009 | ||||||||||||||||||||||||
| BUFFALO URBAN RENEWAL AGENCY | $4,311,494.00 | Grant | Community Development Block Grant ARRA Entitlement Grants (CDBG-R)(Recovery Act Funded) CDBG-R activities include a variety of community development projects including rehabilitation of single and multi family residential units, infrastructure (streets/sidewalks) improvements, demolitions, a job traiining program, and funding for administration.... Show more | Housing and Urban Development Department | 8/14/2009 | ||||||||||||||||||||||||
| WILLIAMSVILLE CENTRAL SCHOOL DISTRICT INC | $4,310,472.00 | Grant |
State Fiscal Stabilization Fund (SFSF) - Education State Grants, Recovery Act For the support of public elementary, secondary, and post secondary education and, as, applicable early childhood education programs and services
This spending item is part of a $1,653,930,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 5/08/2009 | ||||||||||||||||||||||||
| BUFFALO URBAN RENEWAL AGENCY | $3,872,381.00 | Grant |
Homelessness Prevention and Rapid Re-Housing Program (Recovery Act Funded) It is estimated that this program will be able to assist 825 clients per year or 2,474 over the 3 year period of the grant.
This spending item is part of a $6,594,080.00 allocation. See details |
Housing and Urban Development Department / Community Planning and Development | 8/13/2009 | ||||||||||||||||||||||||
| KENMORE BOARD OF EDUCATION (INC) | $3,734,824.00 | Grant |
State Fiscal Stabilization Fund (SFSF) - Education State Grants, Recovery Act For the support of public elementary, secondary, and post secondary education and, as, applicable early childhood education programs and services
This spending item is part of a $1,653,930,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 5/08/2009 | ||||||||||||||||||||||||
| BRYANT & STRATTON COLLEGE INC | $3,727,167.00 | Grant | Federal Pell Grant Program GRANT PROGRAM | Education Department / DOED - Student Financial Assistance Programs | |||||||||||||||||||||||||
| WEST SENECA CENTRAL SCHOOL DISTRICT | $3,688,259.00 | Grant |
State Fiscal Stabilization Fund (SFSF) - Education State Grants, Recovery Act For the support of public elementary, secondary, and post secondary education and, as, applicable early childhood education programs and services
This spending item is part of a $1,653,930,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 5/08/2009 | ||||||||||||||||||||||||
| LANCASTER CENTRAL SCHOOLS | $3,613,834.00 | Grant |
State Fiscal Stabilization Fund (SFSF) - Education State Grants, Recovery Act For the support of public elementary, secondary, and post secondary education and, as, applicable early childhood education programs and services
This spending item is part of a $1,653,930,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 5/08/2009 | ||||||||||||||||||||||||
| TRANSPORTATION, NEW YORK DEPARTMENT OF | $3,570,004.00 | Grant | Highway Planning and Construction Highway Infrastructure Investment Grant: Available for Use in Any Area (flexible) | Transportation Department / Federal Highway Administration | 7/21/2009 | ||||||||||||||||||||||||
| ORCHARD PARK CENTRAL SCHOOL DISTRICT | $3,512,336.00 | Grant |
State Fiscal Stabilization Fund (SFSF) - Education State Grants, Recovery Act For the support of public elementary, secondary, and post secondary education and, as, applicable early childhood education programs and services
This spending item is part of a $1,653,930,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 5/08/2009 | ||||||||||||||||||||||||
| Buffalo & Erie County Workforce Development Consortium, Inc | $3,363,860.00 | Grant |
WIA Youth Activities WIA Youth $71,526,360.00, CFDA 17.259: To provide employment-related services and high quality work experience, including an expanded summer youth work experience component, to America's youth ages 14-24 to prepare them for the workplace. Expenditures: $41,582,896.96. WIA Dislocated Workers $66,368,188.00, CFDA 17.260: To provide a variety of work-related employment and training services, including job training opportunities, to laid-off individuals to support their reentry into the job market. Expenditures: $16,957,161.32. WIA Adult $31,516,111.00, CFDA 17.258: To provide a variety of work-related employment and training services, including job training opportunities, to unemployed or underemployed adults to support their entry or reentry into the job market. Expenditures: $8,160,711.44.... Show more
This spending item is part of a $169,411,000.00 allocation. See details |
Labor Department / Employment and Training Administration | 2/17/2009 | ||||||||||||||||||||||||
| POLISH COMMUNITY CENTER OF BUFFALO INC | $3,254,371.00 | Grant |
Weatherization Assistance for Low-Income Persons Weatherization formula grants allocated to the New York State Division of Housing and Community Renewal (DHCR) under the American Recovery and Reinvestment Act (ARRA). Funds are provided to reduce the energy expenditures of low-income households by coonducted instrumented energy audits and installing energy conservation materials such as insulation, weatherstripping and caulk, high-efficiency heating and hot water systems, high-efficiency electrical fixtures and efficient building materials such as windows and doors. Award amount includes administrative funding (up to 5%) that will be retained by DHCR for administration. Funds are allocated to eligible subrecipients throughout the state who are responsible for proper installation, compliance with program rules and quality assurance. ARRA funds are expected to provide energy conservation assistance for more than 45,000 dwelling units.... Show more
This spending item is part of a $394,687,000.00 allocation. See details |
Energy Department | 4/01/2009 | ||||||||||||||||||||||||
| COMMUNITY ACTION ORGANIZATION OF ERIE COUNTY INC | $3,134,354.00 | Grant |
ARRA - Community Services Block Grant ARRA Supplemental Funding for the Community Services Block Grant (CSBG) Program: Allocate funds to a network of eligible entities to support employment related services which create and sustain economic growth.
This spending item is part of a $86,780,900.00 allocation. See details |
Health and Human Services, Department of / Administration for Children and Families | 4/10/2009 | ||||||||||||||||||||||||
| COMMUNITY ACTION ORGANIZATION OF ERIE COUNTY INC | $3,134,354.00 | Grant |
ARRA - Community Services Block Grant ARRA Supplemental Funding for the Community Services Block Grant (CSBG) Program: Allocate funds to a network of eligible entities to support employment related services which create and sustain economic growth.
This spending item is part of a $86,780,900.00 allocation. See details |
Health and Human Services, Department of / Administration for Children and Families | 4/10/2009 | ||||||||||||||||||||||||
| BOSTON,TOWN | $3,006,000.00 | Loan | Water and Waste Disposal Systems for Rural Communities - ARRA TOA Code 538, Water only loan only - Rural Development funds will be used to install water lines consisting of 35,200 linear feet of pipe and 33 fire hydrants. The project will replace unhealthy wells to improve water quality and service as well as improve fire protection. The project will benefit 453 users.... Show more | Agriculture Department / Rural Utilities Service | 6/30/2009 | ||||||||||||||||||||||||
| New Buffalo Impact, Inc. | $3,000,000.00 | Grant |
Weatherization Assistance for Low-Income Persons Weatherization formula grants allocated to the New York State Division of Housing and Community Renewal (DHCR) under the American Recovery and Reinvestment Act (ARRA). Funds are provided to reduce the energy expenditures of low-income households by coonducted instrumented energy audits and installing energy conservation materials such as insulation, weatherstripping and caulk, high-efficiency heating and hot water systems, high-efficiency electrical fixtures and efficient building materials such as windows and doors. Award amount includes administrative funding (up to 5%) that will be retained by DHCR for administration. Funds are allocated to eligible subrecipients throughout the state who are responsible for proper installation, compliance with program rules and quality assurance. ARRA funds are expected to provide energy conservation assistance for more than 45,000 dwelling units.... Show more
This spending item is part of a $394,687,000.00 allocation. See details |
Energy Department | 4/01/2009 | ||||||||||||||||||||||||
| SPRINGVILLE, VILLAGE OF | $3,000,000.00 | Loan | Water and Waste Disposal Systems for Rural Communities - ARRA 539 - (Loan Only) Waste Disposal Only - 09/10 Stimulus | Agriculture Department / Rural Utilities Service | 7/27/2009 | ||||||||||||||||||||||||
| ALLIANCE CONTRACTING, LLC | $2,919,354.00 | Contract |
Provide all labor, materials , tools and equipment necessary for our project at the VA Western New York Healthcare System, Buffalo NY.
This spending item is part of a $3,186,390.00 allocation. See details |
Department of Veterans Affairs | 5/13/2009 | ||||||||||||||||||||||||
| ALLIANCE CONTRACTING, LLC | $2,919,354.00 | Contract |
furnish all labor, materials, equipment, etc. necessary for our project called RENOVATE WARD 9A at the VA Medical Center
This spending item is part of a $3,186,390.00 allocation. See details |
Department of Veterans Affairs | 5/13/2009 | ||||||||||||||||||||||||
| ERIE, COUNTY OF NEW YORK | $2,903,000.00 | Grant | Energy Efficiency and Conservation Block Grant Program (EECBG) The overall purpose of the the Erie County, NY Energy Efficiency and Conservation Block Grant is to implement projects that will reduce energy use and green house gas emissions within county operations and the community. The County has pplanned 7 projects to meet those goals: 1. County Energy Plan GÇô This project will set goals and priorities for energy related projects for County operations, as well as the community as a whole, thus providing an excellent opportunity for the County to plan for cost-saving projects.; 2. Energy Plan Projects - The energy efficiency measures to be taken for this project are yet to be determined and will be identified through the County Energy Plan.; 3. A County Greenhouse Gas Reduction Team GÇô This interdepartmental project will identify and execute 'green practices to conserve resources and produce cost savings.; 4.Food Composting GÇô This project will provide technical assistance to businesses (grocery stores, restaurants, hotels, and a compost facility) that are in need of and have requested the CountyGÇÖs assistance; 5. Study and Design Plans for the Replacement of the Erie County Correctional FacilityGÇÖs Boiler System; 6. Study and Design Plans for Improving the Efficiency of the Rath Building GÇô This project will evaluate the entire HVAC (Heating Ventilation & Air Conditioning) system to determine operational characteristics and overall system effectiveness. The evaluation will ultimately lead to a renovation of the head-end (major mechanical unit) equipment and distribution systems. This project will include the preparation of construction documents (design plans and specification) for the initial renovation work.; and 7. Small Building Retrofits - Implementation of energy conservation measures (ECMs) as previously determined by energy audits conducted by CJ Brown Energy, PC through the NYSERDA (New York State Energy Research and Development Authority) Energy Smart Audit Program.... Show more | Energy Department | 12/29/2009 | ||||||||||||||||||||||||
| CLEVELAND BIOLABS, INC. | $2,844,359.00 | Grant | Trans-NIH Recovery Act Research Support The severity of radiation injury in humans is largely determined by high sensitivity of the gastrointestinal (GI) tract, yet no drugs are approved for this indication. This award is focused on a novel, clinical-stage drug candidate, Protectan CBLB502, a Toll-liike receptor 5 (TLR5) agonist capable of effective mitigation of otherwise lethal radiation-induced GI injury in mice and non-human primates (NHPs). A comprehensive understanding of mechanisms of action is required for drug development under the FDA Animal Efficacy Rule. Accordingly, the main objective of this proposal is to use mouse and NHP models to charaterize in detail the mitigating effect of CBLB502 on various elements of the GI system and to identify cellular and molecular mediators of this effect. Specifically, our multi-institutional collaborative team will: (i) create a comprehensive 'histological atlas' illustrating the mitigating effects of CBLB502 on various elements of GI infrastructure damaged by radiation, (ii) define the target organs that contribute to the GI radiomitigation activity of CBLB502 with specific focus on bone marrow and liver, and (iii) identify primary and secondary cellular and molecular conductors of the radiomitigating function of the drug as well as novel efficacy biomarkers. Completion of this program should create a solid mechanistic base for translation of animal data into a well-justified projected human efficacious dose and will be critical for FDA approval of CBLB502 as a medical countermeasure to mitigate GI radiation damage. ... Show more | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 | ||||||||||||||||||||||||
| BUFFALO, CITY OF | $2,736,900.00 | Grant | Energy Efficiency and Conservation Block Grant Program (EECBG) RECOVERY ACT: CITY OF BUFFALO, NY ENERGY EFFICIENCY AND CONSERVATION BLOCK GRANT | Energy Department | 11/19/2009 | ||||||||||||||||||||||||
| BUFFALO, CITY OF | $2,616,421.00 | Grant | Recovery Act - Edward Byrne Memorial Justice Assistance Grant (JAG) Program / Grants To Units Of Local Government Jag stimulus funding engages a partnership between the City of Buffalo and 11 suburban law enforcement partners focusing on crime reduction through job creation/preservation; purchasing eequipment and technology and community initiatives that promote safety partnerships between the police and the community. Deliverables include: selective enforcement overtime, job creation in criminal justice agencies and community-based providers; prevention/intervention opportunities and re-entry services, as well as replacing obsolete and unserviceable police equipment.... Show more | Justice Department | 5/29/2009 | ||||||||||||||||||||||||
| FRONTIER CENTRAL SCHOOL DISTRICT, INC | $2,523,160.00 | Grant |
State Fiscal Stabilization Fund (SFSF) - Education State Grants, Recovery Act For the support of public elementary, secondary, and post secondary education and, as, applicable early childhood education programs and services
This spending item is part of a $1,653,930,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 5/08/2009 | ||||||||||||||||||||||||
| TRANSPORTATION, NEW YORK DEPARTMENT OF | $2,383,814.00 | Grant | Highway Planning and Construction Highway Infrastructure Investment Grant: Available for Use in Any Area (flexible) | Transportation Department / Federal Highway Administration | 3/30/2009 | ||||||||||||||||||||||||
| CLARENCE CENTRAL SCHOOL DISTRICT | $2,368,771.00 | Grant |
State Fiscal Stabilization Fund (SFSF) - Education State Grants, Recovery Act For the support of public elementary, secondary, and post secondary education and, as, applicable early childhood education programs and services
This spending item is part of a $1,653,930,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 5/08/2009 | ||||||||||||||||||||||||
| Buffalo & Erie County Workforce Development Consortium, Inc | $2,292,649.00 | Grant |
WIA Youth Activities WIA Youth $71,526,360.00, CFDA 17.259: To provide employment-related services and high quality work experience, including an expanded summer youth work experience component, to America's youth ages 14-24 to prepare them for the workplace. Expenditures: $41,582,896.96. WIA Dislocated Workers $66,368,188.00, CFDA 17.260: To provide a variety of work-related employment and training services, including job training opportunities, to laid-off individuals to support their reentry into the job market. Expenditures: $16,957,161.32. WIA Adult $31,516,111.00, CFDA 17.258: To provide a variety of work-related employment and training services, including job training opportunities, to unemployed or underemployed adults to support their entry or reentry into the job market. Expenditures: $8,160,711.44.... Show more
This spending item is part of a $169,411,000.00 allocation. See details |
Labor Department / Employment and Training Administration | 2/17/2009 | ||||||||||||||||||||||||
| NIAGARA FRONTIER TRANSPORTATION AUTHORITY | $2,234,070.00 | Grant | Rail and Transit Security Grant Program (ARRA) American Recovery and Reinvestment Act Rail and Transit Security Grant Program-Law Enforcement. The purpose of this grant is to reduce transit system risks and stimulate job creation. The grant will fund the salaries of six new Niagara Frontier Transporttation Authority (NFTA) Transit Police Department Officers, including two new K-9 team transit police officers for three years, and two trained K-9 team police dogs. Training, equipment, and support for the new officers will be funded as well.... Show more | Homeland Security Department / DHS - Federal Emergency Management Agency | 7/31/2009 | ||||||||||||||||||||||||
| HAMBURG CENTRAL SCHOOL SYSTEM | $2,017,325.00 | Grant |
State Fiscal Stabilization Fund (SFSF) - Education State Grants, Recovery Act For the support of public elementary, secondary, and post secondary education and, as, applicable early childhood education programs and services
This spending item is part of a $1,653,930,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 5/08/2009 | ||||||||||||||||||||||||
| ECOSTAR, LLC | $2,000,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| AMERICAN RED CROSS | $2,000,000.00 | Grant |
Homelessness Prevention and Rapid Re-Housing Program (Recovery Act Funded) It is estimated that this program will be able to assist 825 clients per year or 2,474 over the 3 year period of the grant.
This spending item is part of a $6,594,080.00 allocation. See details |
Housing and Urban Development Department / Community Planning and Development | 8/13/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $2,000,000.00 | Grant | Trans-NIH Recovery Act Research Support Cardiovascular molecular imaging is a rapidly emerging area offering considerable promise for the evaluation of patients with heart and vascular disease. While proof of concept studies using novel imaging agents and micro PET have been conducted in mouse modelss of heart disease, their translation to humans and large animal models has been problematic since the human heart is 2000 times larger and dosimetry and tracer localization are considerably different. This proposal requests support to advance preclinical and clinical translational cardiovascular molecular imaging by acquiring a hybrid positron emission tomography (PET) and multidetector computed tomography (CT) scanner dedicated to research. It will support and enhance the ongoing investigational imaging programs of seven major users (supported by 9 RO1 awards and 2 K awards focused on cardiovascular imaging). The proposed GE Discovery VCT is a state of the art PET/CT scanner that will permit preclinical studies of vascular and myocardial structure coupled with molecular imaging using novel cyclotron generated radiopharmaceuticals developed at the adjacent UB Center for Positron Emission Tomography. The Center for Research in Cardiovascular Medicine and Toshiba Stroke Center at the University at Buffalo are interdisciplinary cardiovascular research centers that are recognized leaders in translational cardiovascular imaging. NIH supported studies routinely employ advanced cardiovascular imaging in porcine models of chronic ischemic heart disease and large animal models of stroke. Besides basic mechanistic research, active programs exist in therapeutics including vascular stents, in vivo gene transfer and cardiovascular repair with stem cells (mesenchymal stem cells and endothelial progenitor cells). There is also a large ongoing NIH supported clinical trial to determine if PET can predict the risk of sudden cardiac death in patients by quantifying the extent of hibernating myocardium and imaging inhomogeneity in sympathetic innervation using 11C-Hydroxyephedrine (Prediction of Arrhythmic Events with Positron Emission Tomography). The combined institutional expertise in large animal disease models including hibernating myocardium, coronary disease, cerebrovasular disease and ischemic cardiomyopathy along with patient oriented research in cardiac PET, quantitative image analysis and radiochemistry synthesis are unique strengths of this investigative team. The proposed instrument and synergy between these two teams will facilitate rapid advancements in the field of molecular imaging as applied to the cardiovascular system. PUBLIC HEALTH RELEVANCE: Heart disease continues to be one of the leading causes of death and disability. The proposed PET/CT system will advance bench to bedside research of potentially clinically relevant therapies by focusing on research at the preclinical to clinical translational interface. Such multilevel translational research ultimately has a high likelihood of directly impacting patient care and improving health outcomes. `... Show more | Health and Human Services, Department of / National Institutes of Health | 4/28/2009 | ||||||||||||||||||||||||
| NIAGARA, COUNTY OF | $1,995,361.00 | Grant |
Highway Planning and Construction Highway Infrastructure Investment Grant: Available for Use in Any Area (flexible)
This spending item is part of a $2,388,000.00 allocation. See details |
Transportation Department / Federal Highway Administration | 6/15/2009 | ||||||||||||||||||||||||
| TRANSPORTATION, NEW YORK DEPARTMENT OF | $1,914,426.00 | Grant |
Highway Planning and Construction Highway Infrastructure Investment Grant: Urbanized Areas over 200K Population
This spending item is part of a $1,914,430.00 allocation. See details |
Transportation Department / Federal Highway Administration | 7/01/2009 | ||||||||||||||||||||||||
| SWEET HOME CENTRAL SCHOOL DISTRICT | $1,808,556.00 | Grant |
State Fiscal Stabilization Fund (SFSF) - Education State Grants, Recovery Act For the support of public elementary, secondary, and post secondary education and, as, applicable early childhood education programs and services
This spending item is part of a $1,653,930,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 5/08/2009 | ||||||||||||||||||||||||
| GRAND ISLAND CENTRAL SCHOOL DISTRICT | $1,795,228.00 | Grant |
State Fiscal Stabilization Fund (SFSF) - Education State Grants, Recovery Act For the support of public elementary, secondary, and post secondary education and, as, applicable early childhood education programs and services
This spending item is part of a $1,653,930,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 5/08/2009 | ||||||||||||||||||||||||
| IROQUOIS CENTRAL SCHOOL DISTRICT | $1,692,423.00 | Grant |
State Fiscal Stabilization Fund (SFSF) - Education State Grants, Recovery Act For the support of public elementary, secondary, and post secondary education and, as, applicable early childhood education programs and services
This spending item is part of a $1,653,930,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 5/08/2009 | ||||||||||||||||||||||||
| ST ANDREWS TOWERS | $1,684,800.00 | Grant | Section 8 Housing Assistance Payments Program Special Allocations (Recover Contract Svs S8 Funds | Housing and Urban Development Department / Federal Housing Commissioner | |||||||||||||||||||||||||
| INTOMES TECHNICAL SERVICES | $1,552,938.14 | Contract |
The Recovery Act vision at the West Valley Demonstration Project (WVDP) is to create jobs and Western New York stimulus while safely reducing the site footprint and accelerating work in support of the decommissioning of the WVDP. Six major activities/goals have been established. These objectives aare as follows: 1.Accelerate decontamination of the former nuclear fuel reprocessing Main Plant Process Building (MPPB) in preparation for demolition 2.Install systems to solidify higher-activity radioactive liquids presently stored in the MPPB 3.Install systems to dry the four underground waste tanks and surrounding concrete vaults (To be complete: 12/31/2010) 4.Install systems to mitigate the GW plume contaminated with Sr-90 5.Accelerate stored radioactive waste processing/packaging 6.Remove the 01-14 Building adjacent to the MPPB... Show more
This spending item is part of a $73,875,000.00 allocation. See details |
Energy Department | 9/30/2009 | ||||||||||||||||||||||||
| ATLAS PAINTING AND SHEETING CORP. | $1,550,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| PRAXAIR, INC. | $1,538,342.00 | Grant |
Industrial Carbon Capture and Storage (CCS) Application Carbon Capture and Sequestration from a Hydrogen Production Facility in an Oil Refinery. The project is a commercial demonstration of advanced technologies that capture and sequester CO2 emissions from an existing hydrogen production facility iin an oil refinery into underground formations in combination with Enhanced Oil Recovery (EOR).... Show more
This spending item is part of a $1,588,340.00 allocation. See details |
Energy Department | 11/16/2009 | ||||||||||||||||||||||||
| LACKAWANNA MUNICIPAL HOUSING AUTHORITY | $1,459,353.00 | Grant | Public Housing Capital Fund Stimulus (Formula) Recovery Act Funded Conduct modernization activities at various public housing developments. this funding can be expected to result in providing modernization improvements to the Authority. | Housing and Urban Development Department | 3/18/2009 | ||||||||||||||||||||||||
| Buffalo & Erie County Workforce Development Consortium, Inc | $1,394,968.00 | Grant |
WIA Youth Activities WIA Youth $71,526,360.00, CFDA 17.259: To provide employment-related services and high quality work experience, including an expanded summer youth work experience component, to America's youth ages 14-24 to prepare them for the workplace. Expenditures: $41,582,896.96. WIA Dislocated Workers $66,368,188.00, CFDA 17.260: To provide a variety of work-related employment and training services, including job training opportunities, to laid-off individuals to support their reentry into the job market. Expenditures: $16,957,161.32. WIA Adult $31,516,111.00, CFDA 17.258: To provide a variety of work-related employment and training services, including job training opportunities, to unemployed or underemployed adults to support their entry or reentry into the job market. Expenditures: $8,160,711.44.... Show more
This spending item is part of a $169,411,000.00 allocation. See details |
Labor Department / Employment and Training Administration | 2/17/2009 | ||||||||||||||||||||||||
| EVANS BRANT CENTRAL SCH DIST | $1,374,514.00 | Grant |
State Fiscal Stabilization Fund (SFSF) - Education State Grants, Recovery Act For the support of public elementary, secondary, and post secondary education and, as, applicable early childhood education programs and services
This spending item is part of a $1,653,930,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 5/08/2009 | ||||||||||||||||||||||||
| BUFFALO, CITY OF | $1,360,041.11 | Grant |
Highway Planning and Construction Highway Infrastructure Investment Grant: Available for Use in Any Area (flexible)
This spending item is part of a $2,300,000.00 allocation. See details |
Transportation Department / Federal Highway Administration | 4/29/2009 | ||||||||||||||||||||||||
| AUTUMN WOODS ASSOCIATES L.P. | $1,355,354.00 | Grant | Section 8 Housing Assistance Payments Program Special Allocations (Recover Contract Svs S8 Funds | Housing and Urban Development Department / Federal Housing Commissioner | |||||||||||||||||||||||||
| SPRINGVILLE-GRIFFITH INSTITUTE CENTRAL SCHOOL DISTRICT | $1,341,977.00 | Grant |
State Fiscal Stabilization Fund (SFSF) - Education State Grants, Recovery Act For the support of public elementary, secondary, and post secondary education and, as, applicable early childhood education programs and services
This spending item is part of a $1,653,930,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 5/08/2009 | ||||||||||||||||||||||||
| WILLIAMSVILLE CENTRAL SCHOOL DISTRICT INC | $1,305,899.00 | Grant |
Special Education Grants to States, Recovery Act Assist States in providing special education and related services to children with disabilities in accordance with Part B of the IDEA
This spending item is part of a $759,193,000.00 allocation. See details |
Education Department / Office of Special Education and Rehabilitative Services | 4/01/2009 | ||||||||||||||||||||||||
| HEALTH RESEARCH, INC. | $1,300,294.00 | Grant | Trans-NIH Recovery Act Research Support The Roswell Park Cancer Institute (RPCI) has been continuously recognized as a Comprehensive Cancer Center since the NCI designation of such centers in 1974 and is now requesting continued federal support for the next five years. A free-standing research, educaation and clinical cancer care Institute, RPCI occupies a 27 acre campus near downtown Buffalo and has expanded to nearly 1.6M gsf of clinical and research space, a 16% increase since the last review period. RPCI serves a population base of ~1.5M in Western New York where the RPCI tumor registry is recording more than 3,400 new cancer patients per year. RPCI has strong collaborations with the University of Buffalo and the Hauptman-Woodward Institute for Structural Biology, but is a fully independent entity with Dr. Donald Trump, CCSG PI and RPCI President/CEO, answering only to the RPCI Board of Directors. Since the last competitive renewal, the RPCI has grown significantly as demonstrated by: 1) the recruitment of over 100 new faculty clinicians and researchers of which 43 are new CCSG members; 2) a 74% increase in total NCI funding and a 44% increase in total peer-reviewed funding; 3) a 73% increase in accrual to investigator-initiated, interventional clinical trials and a 44% increase to accrual in all interventional trials; 4) the addition of 4 new shared resources with an institutional investment of over $2.0 M and (5) the opening of a new, 177,000 gsf, state-of-the-art research building housing Program member laboratories and Shared Resources. With the growth in faculty has also come the recruitment of three Senior Leaders. In addition, a director for the newly created RPCI Office of Cancer Health Disparities Research has also been recruited. As part of the scientific growth within RPCI, a new disease-specific Research Program, the Prostate Program, has been added in this renewal bringing RPCI to a total of six Scientific Programs that also include Cancer Prevention & Population Sciences, Cell Stress & Biophysical Therapies, Genetics, Molecular Targets & Experimental Therapeutics and Tumor Immunology & Immunotherapy. With strong leadership and institutional commitment, RPCI will continue to focus on recruiting talented investigators to further expand research efforts targeting areas in genetics, investigational imaging and cancer health disparities.... Show more | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 | ||||||||||||||||||||||||
| KENMORE BOARD OF EDUCATION (INC) | $1,297,187.00 | Grant |
Special Education Grants to States, Recovery Act Assist States in providing special education and related services to children with disabilities in accordance with Part B of the IDEA
This spending item is part of a $759,193,000.00 allocation. See details |
Education Department / Office of Special Education and Rehabilitative Services | 4/01/2009 | ||||||||||||||||||||||||
| DEPEW UNION FREE SCHOOL DISTRICT | $1,268,013.00 | Grant |
State Fiscal Stabilization Fund (SFSF) - Education State Grants, Recovery Act For the support of public elementary, secondary, and post secondary education and, as, applicable early childhood education programs and services
This spending item is part of a $1,653,930,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 5/08/2009 | ||||||||||||||||||||||||
| TRANSPORTATION, NEW YORK DEPARTMENT OF | $1,221,901.00 | Grant | Highway Planning and Construction Highway Infrastructure Investment Grant: Available for Use in Any Area (flexible) | Transportation Department / Federal Highway Administration | 5/26/2009 | ||||||||||||||||||||||||
| COMMUNITY ACTION ORGANIZATION OF ERIE COUNTY INC | $1,221,558.00 | Grant | ARRA - Head Start Early Head Start ARRA Expansion | Health and Human Services, Department of / Administration for Children and Families | 11/01/2009 | ||||||||||||||||||||||||
| ERIE, COUNTY OF | $1,209,200.00 | Grant | Homelessness Prevention and Rapid Re-Housing Program (Recovery Act Funded) The Homelessness Prevention and Rapid Re-Hoising Program shall provide housing assistance to low income individuals and families that are homeless or at risk of becoming homeless. The Program, named Erie County Housing/Homeleess Outreach Program, shall provide financial assistance and cousneling service to approximately 1000 homeless or at risk of becoming homeless households in the Erie County CDBG Consortium. Financial assistance will be available to assist eligible households to pay rent, utility payments, security deposits, moving assistance, motel/hotel vouchers. In addition to financial assistance eligible households shall receive case management, legal services, housing search/placement and credit repair, if needed.... Show more | Housing and Urban Development Department | 7/20/2009 | ||||||||||||||||||||||||
| David M. Gordon | $1,200,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| BRYANT & STRATTON COLLEGE INC | $1,177,403.00 | Grant | Federal Pell Grant Program GRANT PROGRAM | Education Department / DOED - Student Financial Assistance Programs | |||||||||||||||||||||||||
| COMMUNITY ACTION ORGANIZATION OF ERIE COUNTY INC | $1,174,675.00 | Grant | ARRA - Head Start FY 2009 ARRA COLA/QI | Health and Human Services, Department of / Administration for Children and Families | 7/01/2009 | ||||||||||||||||||||||||
| LUEDTKE ENGINEERING COMPANY | $1,173,750.00 | Contract | FY09 Maintenance Dredging Black Rock Channel Buffalo, Erie County, NY | U.S. Army Corps of Engineers / U.S. Army Corps of Engineers - civil program financing only | 7/31/2009 | ||||||||||||||||||||||||
| Boncraft Printing Group | $1,156,200.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| AMHERST C H S SCH DIST 1 | $1,125,352.00 | Grant |
State Fiscal Stabilization Fund (SFSF) - Education State Grants, Recovery Act For the support of public elementary, secondary, and post secondary education and, as, applicable early childhood education programs and services
This spending item is part of a $1,653,930,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 5/08/2009 | ||||||||||||||||||||||||
| TRANSPORTATION, NEW YORK DEPARTMENT OF | $1,071,396.10 | Grant |
Highway Planning and Construction Highway Infrastructure Investment Grant: Available for Use in Any Area (flexible)
This spending item is part of a $7,000,000.00 allocation. See details |
Transportation Department / Federal Highway Administration | 4/29/2009 | ||||||||||||||||||||||||
| AMHERST, TOWN OF | $1,052,700.00 | Grant | Energy Efficiency and Conservation Block Grant Program (EECBG) EE CONSERVATION BLOCK GRANT PROGRAM - TOWN OF AMHERST | Energy Department | 11/06/2009 | ||||||||||||||||||||||||
| MULTIPLE RECIPIENTS | $1,051,269.00 | Loan | Very Low to Moderate Income Housing Loans - Guaranteed Single Family Housing Guaranteed Loans - ARRA | Agriculture Department / Rural Housing Service | |||||||||||||||||||||||||
| CHEEKTOWAGA MARYVALE UNION FREE SCHOOL DISTRICT | $1,049,092.00 | Grant |
State Fiscal Stabilization Fund (SFSF) - Education State Grants, Recovery Act For the support of public elementary, secondary, and post secondary education and, as, applicable early childhood education programs and services
This spending item is part of a $1,653,930,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 5/08/2009 | ||||||||||||||||||||||||
| Cheektowaga Central School District | $976,858.00 | Grant |
State Fiscal Stabilization Fund (SFSF) - Education State Grants, Recovery Act For the support of public elementary, secondary, and post secondary education and, as, applicable early childhood education programs and services
This spending item is part of a $1,653,930,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 5/08/2009 | ||||||||||||||||||||||||
| K-Technologies Inc. | $969,000.00 | Loan | 504 Certified Development Loans TO ASSIST SMALL BUSINESS CONCERNS BY PROVIDING LONG TERM FINANCING THROUGH THE SALE OF DEBENTURES TO THE PRIVATE SECTOR | Small Business Administration | |||||||||||||||||||||||||
| MARILLA, TOWN OF | $967,000.00 | Loan | Water and Waste Disposal Systems for Rural Communities - ARRA TOA Code 544, Water only combo loan/grant - Rural Development funds will be used to install 15,000 feet of PVC pipe with one large and three small creek crossings to improve water for residents in the area who are experiencing insufficientt quantity and poor water quality. The project will benefit 148 users.... Show more | Agriculture Department / Rural Utilities Service | 9/04/2009 | ||||||||||||||||||||||||
| FORGE CONSULTING, LLC | $945,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| TRANSPORTATION, NEW YORK DEPARTMENT OF | $939,958.89 | Grant |
Highway Planning and Construction Highway Infrastructure Investment Grant: Available for Use in Any Area (flexible)
This spending item is part of a $2,300,000.00 allocation. See details |
Transportation Department / Federal Highway Administration | 4/29/2009 | ||||||||||||||||||||||||
| WEST SENECA CENTRAL SCHOOL DISTRICT | $932,839.00 | Grant |
Special Education Grants to States, Recovery Act Assist States in providing special education and related services to children with disabilities in accordance with Part B of the IDEA
This spending item is part of a $759,193,000.00 allocation. See details |
Education Department / Office of Special Education and Rehabilitative Services | 4/01/2009 | ||||||||||||||||||||||||
| FISHER POOLS & SUPPLIES | $925,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| KEN-TON PRESBYTERIAN E | $923,484.00 | Grant | Section 8 Housing Assistance Payments Program Special Allocations (Recover Contract Svs S8 Funds | Housing and Urban Development Department / Federal Housing Commissioner | |||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $910,000.00 | Grant | Trans-NSF Recovery Act Reasearch Support It will fund the research work of the High Energy Group at the State University of New York at Buffalo. The group main research activities are on the D0 experiment at the Tevatron, the CMS experiment at LHC, and the outreach program through QuarkNet. The reseaarch program plans to initially investigate the production of Standard Model processes and than to search for the Higgs particles at the CMS experiment. The background processes are important to themselves as they provide crucial test of the Standard Model in areas least explored so far. The group will continue its participation in the Forward Pixel Detector project. This participation should allow postdocs and graduate students to acquire a balanced education by combining activities of data analyses and detector commissioning and operation. The D0 detector has recorded in excess of 4fb-1 of data to date and is expected to substantially increase the integrated luminosity in the coming years. The goal of the proposed research program with D0 is to study Z decay to bbar and ZZ production processes. These analyses will greatly benefit from the increased dataset and well calibrated and understood detector. As for broader impact the research program will be fostering collaboration between the State University of New York at Buffalo group members, high school teachers and their students. They open... Show more | National Science Foundation | 6/05/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $910,000.00 | Grant | Trans-NSF Recovery Act Reasearch Support It will fund the research work of the High Energy Group at the State University of New York at Buffalo. The group main research activities are on the D0 experiment at the Tevatron, the CMS experiment at LHC, and the outreach program through QuarkNet. The reseaarch program plans to initially investigate the production of Standard Model processes and than to search for the Higgs particles at the CMS experiment. The background processes are important to themselves as they provide crucial test of the Standard Model in areas least explored so far. The group will continue its participation in the Forward Pixel Detector project. This participation should allow postdocs and graduate students to acquire a balanced education by combining activities of data analyses and detector commissioning and operation.-á The D0 detector has recorded in excess of 4fb-1 of data to date and is expected to substantially increase the integrated luminosity in the coming years. The goal of the proposed research program with D0 is to study Z decay to bbar and ZZ production processes. These analyses will greatly benefit from the increased dataset and well calibrated and understood detector. As for broader impact the research program will be fostering collaboration between the State University of New York at Buffalo group members, high school teachers and their students. They open... Show more | National Science Foundation | 6/05/2009 | ||||||||||||||||||||||||
| AMERICAN REMEDIATION SOLUTIONS AND ENVIRONMENTAL CORPORATION | $901,733.10 | Contract | Tonawanda Landfill Remediation | U.S. Army Corps of Engineers / U.S. Army Corps of Engineers - civil program financing only | 7/30/2009 | ||||||||||||||||||||||||
| CANISIUS COLLEGE OF BUFFALO | $900,593.00 | Grant | Federal Pell Grant Program GRANT PROGRAM | Education Department / DOED - Student Financial Assistance Programs | |||||||||||||||||||||||||
| TVGA CONSULTANTS | $900,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| TONAWANDA BOARD OF EDUCATION | $873,452.00 | Grant |
State Fiscal Stabilization Fund (SFSF) - Education State Grants, Recovery Act For the support of public elementary, secondary, and post secondary education and, as, applicable early childhood education programs and services
This spending item is part of a $1,653,930,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 5/08/2009 | ||||||||||||||||||||||||
| D.V. Brown & Associates, Inc. | $867,400.00 | Contract |
furnish all labor, materials, equipment, etc. necessary for our project called RENOVATE WARD 9A at the VA Medical Center
This spending item is part of a $3,186,390.00 allocation. See details |
Department of Veterans Affairs | 5/13/2009 | ||||||||||||||||||||||||
| BUFFALO CITY SCHOOL DISTRICT | $855,000.00 | Grant |
State Fiscal Stabilization Fund (SFSF) - Government Services, Recovery Act Government Services Fund - for public safety and other government services which may include assistance for elementary and secondary education and public institutions of higher education, and for modernization , renovation or repair of public school facilities and institutions of higher education facilities, including modernization, renovation and repairs that are consistent with a recognized green building rating... Show more
This spending item is part of a $367,990,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 5/08/2009 | ||||||||||||||||||||||||
| Fruit Fresh Up Inc. | $848,000.00 | Loan | 504 Certified Development Loans TO ASSIST SMALL BUSINESS CONCERNS BY PROVIDING LONG TERM FINANCING THROUGH THE SALE OF DEBENTURES TO THE PRIVATE SECTOR | Small Business Administration | |||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $845,796.00 | Grant | Trans-NSF Recovery Act Reasearch Support The ICCAP research project's main goals are 1) the extent to which the circumpolar area has been subject to varying trends of environmental change in the past and 2) the similarities and differences in human adaptations to these changes in different areas of tthe Arctic. The research team will employ a well tested collection of direct and indirect proxies of climate and human adaptation based upon methods from dendro-climatology, palynology, geo-chemistry, climate modeling, ethnography, and archaeology. The very successful predecessor of this project, SCENOP of the European Science Foundation BOREAS program, created and compared two data sets from northern Finland and northern Canada. ICCAP creates a new data set from northern Russia and combined with its predecessor will provide three approximately equidistant placed research areas encompassing the entire the circumpolar world. For each research area, the employing the same research teams using the same methodologies at the same levels of resolution makes possible meaningful comparisons from uniformly collected data. ICCAP adds to the existing ?two way? (Finland, Canada) comparison, two new two way comparisons (Finland, Russia) (Canada, Russia), as well as making truly three way comparisons among the data sets (Finland, Canada, Russia). Because of the circum-global geographic locations, Yli-ii Finland, Wemindji Quebec Canada and Ust-Kamchatsk, Kamchatka, Russia, ICCAP will make circumpolar generalizations.-á By using a long-term perspective on human responses to climate and environmental change in these three coastal circumpolar locations between 60 and 78 degrees N latitude and 7000 to 3000 years ago, the researchers proposed to answer some basic questions that are important for science and policy. For example: in the long run, several thousand years, are yearly average temperatures more important than seasonal temperatures Are absolute temperature and precipitation changes more important than the variability in temperature and precipitation? Does diversity of environmental change result in increasing stability or diversity of human adaptation Are there thresholds that must be met in environmental change or in human adaptation before changes occur Does human adaptation to environmental or climate change need to be reactive or may it successfully be pro-active The circumpolar north widely is seen as a critical observatory for understanding environmental change and human adaptation. This is particularly true today since the effects of global warming are most clearly visible in the Arctic where reality has exceeded expectations?. Ultimately, this project proposes to explain the past and the potential range of human resilience when faced with global and local environmental changes. Taken from the circumpolar perspective, the research team believes that this information has the potential to aid policy makers as they enter into debates on new post-cold-war partnerships, and set policy concerning such issues as energy, post-colonial governance, and strategy.... Show more | National Science Foundation | 6/09/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $845,796.00 | Grant | Trans-NSF Recovery Act Reasearch Support The ICCAP research project's main goals are 1) the extent to which the circumpolar area has been subject to varying trends of environmental change in the past and 2) the similarities and differences in human adaptations to these changes in different areas of tthe Arctic. The research team will employ a ?well tested? collection of direct and indirect proxies of climate and human adaptation based upon methods from dendro-climatology, palynology, geo-chemistry, climate modeling, ethnography, and archaeology. The very successful predecessor of this project, SCENOP of the European Science Foundation BOREAS program, created and compared two data sets from northern Finland and northern Canada. ICCAP creates a new data set from northern Russia and combined with its predecessor will provide three approximately equidistant placed research areas encompassing the entire the circumpolar world. For each research area, the employing the same research teams using the same methodologies at the same levels of resolution makes possible meaningful comparisons from uniformly collected data. ICCAP adds to the existing ?two way? (Finland, Canada) comparison, two new ?two way? comparisons (Finland, Russia) (Canada, Russia), as well as making truly three way comparisons among the data sets (Finland, Canada, Russia). Because of the circum-global geographic locations, Yli-ii Finland, Wemindji Quebec Canada and Ust-Kamchatsk, Kamchatka, Russia, ICCAP will make circumpolar generalizations. By using a long-term perspective on human responses to climate and environmental change in these three coastal circumpolar locations between 60 and 78 degrees N latitude and 7000 to 3000 years ago, the researchers proposed to answer some basic questions that are important for science and policy. For example: in the long run, several thousand years, are yearly average temperatures more important than seasonal temperatures? Are absolute temperature and precipitation changes more important than the variability in temperature and precipitation? Does diversity of environmental change result in increasing stability or diversity of human adaptation? Are there thresholds that must be met in environmental change or in human adaptation before changes occur? Does human adaptation to environmental or climate change need to be reactive or may it successfully be pro-active? The circumpolar north widely is seen as a critical observatory for understanding environmental change and human adaptation. This is particularly true today since the effects of global warming are most clearly visible in the Arctic where ?reality has exceeded expectations?. Ultimately, this project proposes to explain the past and the potential range of human resilience when faced with global and local environmental changes. Taken from the circumpolar perspective, the research team believes that this information has the potential to aid policy makers as they enter into debates on new post-cold-war partnerships, and set policy concerning such issues as energy, post-colonial governance, and strategy.... Show more | National Science Foundation | 6/09/2009 | ||||||||||||||||||||||||
| TRANSPORTATION, NEW YORK DEPARTMENT OF | $841,570.00 | Grant | Highway Planning and Construction Highway Infrastructure Investment Grant: Available for Use in Any Area (flexible) | Transportation Department / Federal Highway Administration | 5/19/2009 | ||||||||||||||||||||||||
| ALDEN CENTRAL SCHOOL DISTRICT | $835,667.00 | Grant |
State Fiscal Stabilization Fund (SFSF) - Education State Grants, Recovery Act For the support of public elementary, secondary, and post secondary education and, as, applicable early childhood education programs and services
This spending item is part of a $1,653,930,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 5/08/2009 | ||||||||||||||||||||||||
| RENEWAL HOUSING CORP | $831,649.00 | Grant | Section 8 Housing Assistance Payments Program Special Allocations (Recover Contract Svs S8 Funds | Housing and Urban Development Department / Federal Housing Commissioner | |||||||||||||||||||||||||
| TRANSPORTATION, NEW YORK DEPARTMENT OF | $826,561.00 | Grant | Highway Planning and Construction Highway Infrastructure Investment Grant: Urbanized Areas over 200K Population | Transportation Department / Federal Highway Administration | 3/19/2009 | ||||||||||||||||||||||||
| Eden Central School District Inc | $816,108.00 | Grant |
State Fiscal Stabilization Fund (SFSF) - Education State Grants, Recovery Act For the support of public elementary, secondary, and post secondary education and, as, applicable early childhood education programs and services
This spending item is part of a $1,653,930,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 5/08/2009 | ||||||||||||||||||||||||
| Gordon Companies, Inc. | $800,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| INSTALLS INC, LLC | $800,000.00 | Contract | Basic In-home Digital converter box installation in CT, DC, DE, MA, MD, ME, NH, NJ, NY, PA, RI and VT. Installed 8,756 boxes. | Federal Communications Commission | 5/15/2009 | ||||||||||||||||||||||||
| East Aurora Union Free School District | $783,419.00 | Grant |
State Fiscal Stabilization Fund (SFSF) - Education State Grants, Recovery Act For the support of public elementary, secondary, and post secondary education and, as, applicable early childhood education programs and services
This spending item is part of a $1,653,930,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 5/08/2009 | ||||||||||||||||||||||||
| LANCASTER CENTRAL SCHOOLS | $776,913.00 | Grant |
Special Education Grants to States, Recovery Act Assist States in providing special education and related services to children with disabilities in accordance with Part B of the IDEA
This spending item is part of a $759,193,000.00 allocation. See details |
Education Department / Office of Special Education and Rehabilitative Services | 4/01/2009 | ||||||||||||||||||||||||
| AKRON CENTRAL SCHOOL | $768,215.00 | Grant |
State Fiscal Stabilization Fund (SFSF) - Education State Grants, Recovery Act For the support of public elementary, secondary, and post secondary education and, as, applicable early childhood education programs and services
This spending item is part of a $1,653,930,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 5/08/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $763,880.00 | Grant | Trans-NIH Recovery Act Research Support Myotonic muscular dystrophy type 1 (DM1) and type 2 (DM2) are caused by a toxic gain of function by expanded repeating RNAs. Both expanded repeats reside in noncoding regions and bind to the splicing regulator muscleblind (MBNL1); the formation of the RNA-proteein complexes causes DM by inactivating MBNL1. Our group has developed a series of modularly assembled, multivalent ligands that specifically bind the DM RNAs with nanomolar affinities and that potently inhibit the formation of the DM RNA-MBNL1 complex in vitro with nanomolar IC50's. These compounds are also permeable to mouse myoblasts when simply added to the culture medium; a subset of the ligands localize to the nucleus, which is where the RNA-MBNL1 interaction occurs in vivo. Because these compounds are high affinity, specific, and cell permeable, they have the potential to be biologically active. Our aims are two-fold: determine the efficacy of modularly assembled, multivalent compounds that target the DM1 repeats in cell culture and to understand the molecular recognition of the RNA-ligand complexes using X-ray crystallography in order to design more potent and selective inhibitors. If successful, these investigations may result in the development of a general strategy to design compounds that target toxic triplet repeating RNAs. Specifically, we propose to: 1. Optimize previously identified, multivalent ligands a.) to disrupt the formation of the DM1 RNA- MBNL1 interaction and to specifically bind the DM1 RNA in vitro and b.) for improved uptake, cellular localization, and toxicity profiles in a mouse myoblast cell line and DM1-affected myoblasts. Ligands identified to bind the DM1 RNA were multivalently displayed on a peptoid backbone. In the proposed studies, the spacing modules between ligands will be changed to optimize inhibition potency and to alter cellular uptake and localization properties. 2. Determine if a series of lead compounds that meet the criteria in Specific Aim 1 can increase translation of rCUG-repeat containing RNAs using a luciferase reporter system, disrupt nuclear foci in DM1-affected myoblasts using a fluorescence in situ hybridization (FISH) assay, and correct splicing defects (insulin receptor) that are associated with DM1 using RT-PCR. 3. Determine the structure of DM 1 and DM2 RNAs in the presence of ligand. Such studies will identify the features of the small molecule that are important for binding the RNA. Derivatives can then be made to improve affinity and specificity. We expect that the proposed work will stimulate the economy by enabling hiring of additional scientific staff, consistent with the goals of Notice Number NOT-09-058, NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. PUBLIC HEALTH RELEVANCE: Myotonic dystrophy (DM) is a genetic disease characterized by wasting of muscle function including organ wasting that leads to cardiac disease, respiratory impairment, cataracts, and a host of other significant problems. At present, there are no therapeutics that treat the cause of DM, the formation of an RNA-protein complex. In this proposal, we describe the determining the biological efficacy of previously developed small molecules to move towards the development of DM therapies and the structural determination of RNA-ligand complexes to design more potent and specific compounds.... Show more | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 | ||||||||||||||||||||||||
| Flexo Transparent Inc. | $758,000.00 | Loan | 504 Certified Development Loans TO ASSIST SMALL BUSINESS CONCERNS BY PROVIDING LONG TERM FINANCING THROUGH THE SALE OF DEBENTURES TO THE PRIVATE SECTOR | Small Business Administration | |||||||||||||||||||||||||
| NORAZZA, INC. | $750,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| ARSENAL CONTRACTING LLC | $749,203.41 | Contract | furnish all labor , materials, equipment and supervision necessary for WARD 7D DIALYSIS OFFICE IMPROVEMENTS | Department of Veterans Affairs | 11/30/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $744,973.00 | Grant | Trans-NSF Recovery Act Reasearch Support Intellectual Merit All animals rely on their ability to sense and respond to their constantly changing environments to survive. Because they do not have eyes or ears, C. elegans (small roundworms) depend heavily upon their ability to taste and smell chemical iinformation in their soil environment to find food and avoid danger; animals must move towards chemicals that indicate a food source while avoiding chemicals that indicate potentially harmful environments. These behavioral responses are elicited when the chemical signals (tastants and odorants) bind to proteins (receptors) on sensory nerve cells (neurons) and initiate a chain of intracellular events that ultimately activates the neuron. Neuronal activity, in turn, controls the behavior of the organism. Although this process of chemical signal transduction is highly conserved across species, there are still large gaps in our understanding of the mechanisms used to regulate signaling. Coupled with powerful genetic and molecular tools, C. elegans is an ideal model system in which to dissect the contributions of individual genes and regulatory pathways to integrated neuronal function and sensory behavior. Loss of a negative regulator of signaling (C. elegans GRK-2) surprisingly leads to decreased calcium signaling in sensory neurons and a concomitant loss of both attractive and avoidance chemosensory behaviors. In the absence of GRK-2 there appears to be an upregulation of compensatory inhibitory pathways that dampen signaling to protect neurons from overstimulation. This project will utilize cellular, biochemical and genetic approaches in a simple model organism to understand how cells respond to aberrant signaling; the findings will benefit researchers working in organisms ranging from yeast to humans. In particular, they will provide valuable information on the interconnectedness of signaling and regulatory pathways downstream of receptors. In addition, novel mechanisms used by cells to compensate for mis-regulated signaling may be revealed. Broader Impact Graduate students and undergraduates, including women and minority students, will participate in these studies. The University at Buffalo (UB) is a very diverse campus, providing a great opportunity to mentor minority students. Funds from this grant will support a summer stipend for an undergraduate from a Liberal Arts College that does not itself have undergraduate research. Providing early exposure to hypothesis-driven research is essential for preparing students for careers in the biological sciences. Students will present their findings at local (monthly), regional and international meetings. Importantly, the annual C. elegans meetings foster the development of junior scientists because many of the speakers are selected from graduate student submitted abstracts. Findings from this work will also be included in the lectures in an undergraduate Signal Transduction course at UB. Mutants obtained from the genetic screens in this project will be deposited at the Caenorhabditis Genetics Center, which will distribute them to any investigator that requests them. New gene and phenotype descriptions will also be incorporated into Wormbase, an online open access resource.... Show more | National Science Foundation | 7/17/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $744,973.00 | Grant | Trans-NSF Recovery Act Reasearch Support Intellectual Merit All animals rely on their ability to sense and respond to their constantly changing environments to survive. Because they do not have eyes or ears, C. elegans (small roundworms) depend heavily upon their ability to taste and smell chemical iinformation in their soil environment to find food and avoid danger; animals must move towards chemicals that indicate a food source while avoiding chemicals that indicate potentially harmful environments. These behavioral responses are elicited when the chemical signals (tastants and odorants) bind to proteins (receptors) on sensory nerve cells (neurons) and initiate a chain of intracellular events that ultimately activates the neuron. Neuronal activity, in turn, controls the behavior of the organism. Although this process of chemical signal transduction is highly conserved across species, there are still large gaps in our understanding of the mechanisms used to regulate signaling. Coupled with powerful genetic and molecular tools, C. elegans is an ideal model system in which to dissect the contributions of individual genes and regulatory pathways to integrated neuronal function and sensory behavior. Loss of a negative regulator of signaling (C. elegans GRK-2) surprisingly leads to decreased calcium signaling in sensory neurons and a concomitant loss of both attractive and avoidance chemosensory behaviors. In the absence of GRK-2 there appears to be an upregulation of compensatory inhibitory pathways that dampen signaling to protect neurons from overstimulation. This project will utilize cellular, biochemical and genetic approaches in a simple model organism to understand how cells respond to aberrant signaling; the findings will benefit researchers working in organisms ranging from yeast to humans. In particular, they will provide valuable information on the interconnectedness of signaling and regulatory pathways downstream of receptors. In addition, novel mechanisms used by cells to compensate for mis-regulated signaling may be revealed.-á Broader Impact Graduate students and undergraduates, including women and minority students, will participate in these studies. The University at Buffalo (UB) is a very diverse campus, providing a great opportunity to mentor minority students. Funds from this grant will support a summer stipend for an undergraduate from a Liberal Arts College that does not itself have undergraduate research. Providing early exposure to hypothesis-driven research is essential for preparing students for careers in the biological sciences. Students will present their findings at local (monthly), regional and international meetings. Importantly, the annual C. elegans meetings foster the development of junior scientists because many of the speakers are selected from graduate student submitted abstracts. Findings from this work will also be included in the lectures in an undergraduate Signal Transduction course at UB. Mutants obtained from the genetic screens in this project will be deposited at the Caenorhabditis Genetics Center, which will distribute them to any investigator that requests them. New gene and phenotype descriptions will also be incorporated into Wormbase, an online open access resource.... Show more | National Science Foundation | 7/17/2009 | ||||||||||||||||||||||||
| ERIE COMMUNITY COLLEGE | $731,496.00 | Grant | Federal Pell Grant Program GRANT PROGRAM | Education Department / DOED - Student Financial Assistance Programs | |||||||||||||||||||||||||
| TRANSPORTATION, NEW YORK DEPARTMENT OF | $726,874.00 | Grant | Highway Planning and Construction Highway Infrastructure Investment Grant: Urbanized Areas over 200K Population | Transportation Department / Federal Highway Administration | 3/19/2009 | ||||||||||||||||||||||||
| FRONTIER CENTRAL SCHOOL DISTRICT, INC | $726,007.00 | Grant |
Special Education Grants to States, Recovery Act Assist States in providing special education and related services to children with disabilities in accordance with Part B of the IDEA
This spending item is part of a $759,193,000.00 allocation. See details |
Education Department / Office of Special Education and Rehabilitative Services | 4/01/2009 | ||||||||||||||||||||||||
| TOWN OF CHEEKTOWAGA | $718,800.00 | Grant | Energy Efficiency and Conservation Block Grant Program (EECBG) The Town of Cheektowaga, NY will install photovoltaic panels on the roofs of five municipally owned buildings, reducing the Town's consumption of fossil fuel generated electricity. The reduction in electricity usage will limit the TownGÇÇÖs dependence on fossil-fuel driven electrical generation, thus limiting its contribution toward greenhouse gas emissions. The photovoltaic systems to be installed on the five municipally owned buildings will reduce green house gas emissions by 4,143 tons of CO2 over the next twenty-five years (estimated life span of the photovoltaic panels). The photovoltaic system will reduce utility costs paid by the Town and its tax base, freeing up resources for future parallel energy improvements. The Town estimates saving $750,350 in utility costs over the 25 year life of the system. The Town anticipates using monies saved to invest in additional photovoltaic systems to be installed on other Town owned facilities in the future. Following is a breakdown of the activity components: Cheektowaga Town Hall located at 3301 Broadway, Cheektowaga, NY 14227 - 78 photovoltaic panels will be installed resulting in reduced green house gas emissions by 13.48 tons annually and a utility savings of $2,493.00 annually. Plant #5 located at 171 Central Blvd., Cheektowaga NY 14225 - 212 photovoltaic panels will be installed resulting in reduced green house gas emissions by 40.5 tons annually and a utility savings of $6,866.00 annually. Cheektowaga Ice Rink located at 214 Ridge Park Avenue, Cheektowaga, NY 14211 - 212 photovoltaic panels will be installed resulting in reduced green house emissions by 38.3 tons annually and a utility savings of $7,086.00 annually. Cheektowaga Highway Department located at 3145 Union Road, Cheektowaga NY 14227 - 212 photovoltaic panels will be installed resulting in reduced green house emissions by 36.6 tons annually and a utility savings of $6,795.00 annually. Cheektowaga Sanitation Department located at 3135 Union Road, Cheektowaga, NY 14227 - 238 photovoltaic panels will be installed resulting in reduced green house gas emissions by 36.8 tons annually and a utility savings of $6,774.00 annually. Project Schedule: Engineering/design - Months 1-3 Bidding Process - Months 4-5 Order, Manufacture, and Deliver of photovoltaic Panels - Months 6 - 12 Project Installation - Months 13 - 18 Project Start Up and Field Verification - Months 19 - 22 The project is estimated to create/retain ten jobs. The total project cost is estimated to be $961,537 including $718,800 in EECBG funds and $242,737 in leveraged funds.... Show more | Energy Department | 12/16/2009 | ||||||||||||||||||||||||
| LACKAWANNA CITY SCHOOL DISTRICT | $714,697.00 | Grant |
State Fiscal Stabilization Fund (SFSF) - Education State Grants, Recovery Act For the support of public elementary, secondary, and post secondary education and, as, applicable early childhood education programs and services
This spending item is part of a $1,653,930,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 5/08/2009 | ||||||||||||||||||||||||
| MEDAILLE COLLEGE | $661,734.00 | Grant | Federal Pell Grant Program GRANT PROGRAM | Education Department / DOED - Student Financial Assistance Programs | |||||||||||||||||||||||||
| TRANSPORTATION, NEW YORK DEPARTMENT OF | $660,000.00 | Grant | Highway Planning and Construction Highway Infrastructure Investment Grant: Available for Use in Any Area (flexible) | Transportation Department / Federal Highway Administration | 4/29/2009 | ||||||||||||||||||||||||
| Sheridan Drive Medical Group LLP | $647,000.00 | Loan | 504 Certified Development Loans TO ASSIST SMALL BUSINESS CONCERNS BY PROVIDING LONG TERM FINANCING THROUGH THE SALE OF DEBENTURES TO THE PRIVATE SECTOR | Small Business Administration | |||||||||||||||||||||||||
| DAEMEN COLLEGE | $639,199.00 | Grant | Federal Pell Grant Program GRANT PROGRAM | Education Department / DOED - Student Financial Assistance Programs | |||||||||||||||||||||||||
| TROCAIRE COLLEGE | $639,012.00 | Grant | Federal Pell Grant Program GRANT PROGRAM | Education Department / DOED - Student Financial Assistance Programs | |||||||||||||||||||||||||
| DYOUVILLE COLLEGE | $635,200.00 | Grant | Federal Pell Grant Program GRANT PROGRAM | Education Department / DOED - Student Financial Assistance Programs | |||||||||||||||||||||||||
| ORCHARD PARK CENTRAL SCHOOL DISTRICT | $627,276.00 | Grant |
Special Education Grants to States, Recovery Act Assist States in providing special education and related services to children with disabilities in accordance with Part B of the IDEA
This spending item is part of a $759,193,000.00 allocation. See details |
Education Department / Office of Special Education and Rehabilitative Services | 4/01/2009 | ||||||||||||||||||||||||
| CATTARAUGUS, COUNTY OF | $620,000.00 | Grant | Highway Planning and Construction Highway Infrastructure Investment Grant: Available for Use in Any Area (flexible) | Transportation Department / Federal Highway Administration | 7/01/2009 | ||||||||||||||||||||||||
| ELLICOTT COMMUNITY REDEVOLP. | $618,735.00 | Grant | Section 8 Housing Assistance Payments Program Special Allocations (Recover Contract Svs S8 Funds | Housing and Urban Development Department / Federal Housing Commissioner | |||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $600,000.00 | Grant | Trans-NSF Recovery Act Reasearch Support Technical Summary Vanadium oxides have a rich and complex phase diagram originating from the facile accessibility of different vanadium oxidation states and the various structural distortions adopted to accommodate non-stoichiometry and point defects. The propposed research project focuses on understanding the influence of finite size on the properties of two intriguing vanadium oxides, VO2 and V2O5. Bulk VO2 shows a dramatic insulator?metal phase transition at ~67??C and represents a textbook problem in solid-state chemistry and physics. The proposed work is inspired by our preliminary results showing a strong size dependence of the phase-transition temperature and hysteresis for VO2 nanostructures prepared by hydrothermal methods. Chemical vapor deposition and hydrothermal approaches for the fabrication of VO2 nanostructures with controlled shape, size, and growth direction will be explored. A systematic investigation of the crystal growth mechanism will be performed to obtain rational and predictive control over the nanostructure dimensions. A combination of ensemble X-ray absorption spectroscopy, Raman spectroscopy, and X-ray diffraction measurements will be used in conjunction with single-nanowire electrical transport and Raman spectroscopy measurements to understand the influence of finite size on the insulator?metal phase transition in these nanostructures. Another aspect of the proposed CAREER proposal will involve the fabrication of V2O5 nanowires and their dielectrophoretic integration within device structures. Simultaneous electrical conductivity and Raman spectroscopy measurements of single nanowires will be performed within device geometries to understand the influence of finite size in modifying the electrical transport and surface conductance of these nanowires in the presence of alcohol vapors. The synthesis and device integration of anisotropic VO2 and V2O5 nanostructures will pave the way for their implementation in optical switching devices, thermochromic coatings, Mott field-effect transistors, alcohol sensors, and waveguides. Non-Technical Summary Nanoscale materials often show properties that are not exhibited by their bulk counterparts. The proposed research effort is focused on understanding how such properties can be harnessed for practical applications such as making faster electronic circuits for use in the next generation of computers, ?smart? window materials that change color with temperature, and accurate sensors for detecting low concentrations of vapors. Vanadium dioxide, one of the materials that will be explored in this project, is a transparent insulator at room temperature but upon heating to 67??C becomes an excellent conductor that is almost completely opaque. The proposed research will focus on shifting this transition closer to room temperature wherein this dramatic effect can be used to construct ultrafast nanoelectronic circuits and temperature-sensitive coatings. An integrated outreach and education program is also proposed emphasizing teacher professional development, classroom engagement, and curricular reform at the middle-school level at a local urban high-needs school. These activities will serve to build sustained mentoring relationships between faculty, graduate students, undergraduate students, and middle-school teachers and students. This effort will seek to actively engage Buffalo Public School middle-school students from economically disadvantaged backgrounds in appreciating science and technology at a critical and formative time period. The collaborative development of attractive curricular material and challenging laboratory experiments along with sustained classroom visitation and after-school science activities will form the cornerstone of this program. A freshman seminar course will be developed to discuss the broader societal implications of nanotechnology.... Show more | National Science Foundation | 5/27/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $600,000.00 | Grant | Trans-NSF Recovery Act Reasearch Support Technical Summary Vanadium oxides have a rich and complex phase diagram originating from the facile accessibility of different vanadium oxidation states and the various structural distortions adopted to accommodate non-stoichiometry and point defects. The propposed research project focuses on understanding the influence of finite size on the properties of two intriguing vanadium oxides, VO2 and V2O5. Bulk VO2 shows a dramatic insulator?metal phase transition at ~67??C and represents a textbook problem in solid-state chemistry and physics. The proposed work is inspired by our preliminary results showing a strong size dependence of the phase-transition temperature and hysteresis for VO2 nanostructures prepared by hydrothermal methods. Chemical vapor deposition and hydrothermal approaches for the fabrication of VO2 nanostructures with controlled shape, size, and growth direction will be explored. A systematic investigation of the crystal growth mechanism will be performed to obtain rational and predictive control over the nanostructure dimensions. A combination of ensemble X-ray absorption spectroscopy, Raman spectroscopy, and X-ray diffraction measurements will be used in conjunction with single-nanowire electrical transport and Raman spectroscopy measurements to understand the influence of finite size on the insulator?metal phase transition in these nanostructures. Another aspect of the proposed CAREER proposal will involve the fabrication of V2O5 nanowires and their dielectrophoretic integration within device structures. Simultaneous electrical conductivity and Raman spectroscopy measurements of single nanowires will be performed within device geometries to understand the influence of finite size in modifying the electrical transport and surface conductance of these nanowires in the presence of alcohol vapors. The synthesis and device integration of anisotropic VO2 and V2O5 nanostructures will pave the way for their implementation in optical switching devices, thermochromic coatings, Mott field-effect transistors, alcohol sensors, and waveguides. Non-Technical Summary Nanoscale materials often show properties that are not exhibited by their bulk counterparts. The proposed research effort is focused on understanding how such properties can be harnessed for practical applications such as making faster electronic circuits for use in the next generation of computers, ?smart? window materials that change color with temperature, and accurate sensors for detecting low concentrations of vapors. Vanadium dioxide, one of the materials that will be explored in this project, is a transparent insulator at room temperature but upon heating to 67??C becomes an excellent conductor that is almost completely opaque. The proposed research will focus on shifting this transition closer to room temperature wherein this dramatic effect can be used to construct ultrafast nanoelectronic circuits and temperature-sensitive coatings. An integrated outreach and education program is also proposed emphasizing teacher professional development, classroom engagement, and curricular reform at the middle-school level at a local urban high-needs school. These activities will serve to build sustained mentoring relationships between faculty, graduate students, undergraduate students, and middle-school teachers and students. This effort will seek to actively engage Buffalo Public School middle-school students from economically disadvantaged backgrounds in appreciating science and technology at a critical and formative time period. The collaborative development of attractive curricular material and challenging laboratory experiments along with sustained classroom visitation and after-school science activities will form the cornerstone of this program. A freshman seminar course will be developed to discuss the broader societal implications of nanotechnology.... Show more | National Science Foundation | 5/27/2009 | ||||||||||||||||||||||||
| VETERAN ENTERPRISES CO INC | $598,340.40 | Contract |
To preform milling and repaving to the following D Lot Parking Roadway and Golf Lot Parking located @ VA Western NY Health Sytem Buffalo, NY
This spending item is part of a $606,467.00 allocation. See details |
Department of Veterans Affairs | 6/12/2009 | ||||||||||||||||||||||||
| CLEVELAND HILL UNION FREE SD | $588,671.00 | Grant |
State Fiscal Stabilization Fund (SFSF) - Education State Grants, Recovery Act For the support of public elementary, secondary, and post secondary education and, as, applicable early childhood education programs and services
This spending item is part of a $1,653,930,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 5/08/2009 | ||||||||||||||||||||||||
| Holland Central School | $580,132.00 | Grant |
State Fiscal Stabilization Fund (SFSF) - Education State Grants, Recovery Act For the support of public elementary, secondary, and post secondary education and, as, applicable early childhood education programs and services
This spending item is part of a $1,653,930,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 5/08/2009 | ||||||||||||||||||||||||
| TONAWANDA, TOWN OF | $571,117.82 | Grant |
Homelessness Prevention and Rapid Re-Housing Program (Recovery Act Funded) The Homelessness Prevention and Rapid Re-Housing Program will provide financial assistance and services to prevent individuals and families from becoming homeless and help those who are experiencing homelessness to be quickly re-housed and stabilized. The funds under this program are intended to target individuals and families who would be homeless but for this assistance. The funds will provide for a variety of assistance, including: short-term or medium-term rental assistance and housing relocation and stabilization services, including such activities as mediation, credit counseling, security or utility deposits, utility payments, moving cost assistance, and case management. The Tonawanda Temporary Assistance Program details may be viewed at: http://www.tonawanda.ny.us/commdev/... Show more
This spending item is part of a $772,574.00 allocation. See details |
Housing and Urban Development Department | 7/23/2009 | ||||||||||||||||||||||||
| Opf Inc | $570,000.00 | Grant | Highway Planning and Construction Highway Infrastructure Investment Grant: Available for Use in Any Area (flexible) | Transportation Department / Federal Highway Administration | 7/01/2009 | ||||||||||||||||||||||||
| TRANSPORTATION, NEW YORK DEPARTMENT OF | $567,090.00 | Grant | Highway Planning and Construction Highway Infrastructure Investment Grant: Available for Use in Any Area (flexible) | Transportation Department / Federal Highway Administration | 4/29/2009 | ||||||||||||||||||||||||
| NORTHWEST BUFFALO COMMUNITY HEALTH CARE CENTER | $559,995.00 | Grant | ARRA ? Health Center Integrated Services Development Initiative[g1] The Capital Improvement Project is providing funds needed to prepare NWBCHCC for Electronic Health Records. This includes purchasing licenses for Allscripts Practice Management and Eleectronic Health Records. In addition, the fundss are being used to upgrade outdated Information Technology equipment including, servers, computers, routers, phones and the network infra structure.... Show more | Health and Human Services, Department of / Health Resources and Services Administration | 6/25/2009 | ||||||||||||||||||||||||
| NORTHWEST BUFFALO COMMUNITY HEALTH CARE CENTER | $559,995.00 | Grant | ARRA ? Health Center Integrated Services Development Initiative[g1] Capital Improvement Project | Health and Human Services, Department of / Health Resources and Services Administration | 6/25/2009 | ||||||||||||||||||||||||
| WESTERN NEW YORK PUBLIC BROADCASTING ASSOCIATION | $556,395.00 | Grant |
State Fiscal Stabilization Fund (SFSF) - Government Services, Recovery Act Government Services Fund - for public safety and other government services which may include assistance for elementary and secondary education and public institutions of higher education, and for modernization , renovation or repair of public school facilities and institutions of higher education facilities, including modernization, renovation and repairs that are consistent with a recognized green building rating... Show more
This spending item is part of a $367,990,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 5/08/2009 | ||||||||||||||||||||||||
| CLARENCE CENTRAL SCHOOL DISTRICT | $554,145.00 | Grant |
Special Education Grants to States, Recovery Act Assist States in providing special education and related services to children with disabilities in accordance with Part B of the IDEA
This spending item is part of a $759,193,000.00 allocation. See details |
Education Department / Office of Special Education and Rehabilitative Services | 4/01/2009 | ||||||||||||||||||||||||
| JACCARD CORPORATION | $550,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| TONAWANDA, TOWN OF (INC) | $544,700.00 | Grant | Energy Efficiency and Conservation Block Grant Program (EECBG) The Town of Tonawanda, NY will install photovoltaic panels on the roofs of five municipally owned buildings thereby reducing the Town's consumption of fossil fuel generated electricity. The reduction in electricity usage will limit the TTownGÇÖs dependence on fossil-fuel driven electrical generation, thus limiting its contribution toward greenhouse gas emissions. The photovoltaic systems to be installed on the five municipally owned buildings will reduce green house gas emissions by 2,771 tons of CO2 over the next twenty-five years (estimated life span of the photovoltaic panels). The photovoltaic system will reduce utility costs paid by the Town and its tax base, freeing up resources for future parallel energy improvements. The Town estimates saving $802,800 in utility costs over the 25 year life of the system. The Town anticipates using monies saved to invest in additional photovoltaic systems to be installed on other Town owned facilities in the future. Following is a breakdown of the activity components: Tonawanda Highway Department located at 450 Woodward Avenue, Kenmore NY 14217 - 96 photovoltaic panels will be installed resulting in reduced green house gas emissions by 16.2 tons annually and a utility savings of $5,280.00 annually. Tonawanda Police Department located at 1835 Sheridan Drive, Tonawanda NY 14223 - 120 photovoltaic panels will be installed resulting in reduced green house gas emissions by 19 tons annually and a utility savings of $6,168.00 annually. Tonawanda Sewer Maintenance Building located at 525 Belmont Avenue, Tonawanda NY 14223 - 238 photovoltaic panels will be installed resulting in reduced green house emissions by 38.5 tons annually and a utility savings of $10,476.00 annually. Tonawanda Water Treatment Plant located at 218 Aqua Lane, Tonawanda NY 14223 - 120 photovoltaic panels will be installed resulting in reduced green house emissions by 18.5 tons annually and a utility savings of $5,040.00 annually. Tonawanda Waste Water Treatment Facility located at 750 Two Mile Creek Road (mailing address 779 Town Mile Creek Road) Tonawanda, NY 14150 - 120 photovoltaic panels will be installed resulting in reduced green house gas emissions by 19 tons annually and a utility savings of $5,148.00 annually. The project is estimated to create/retain ten jobs. The total project cost is estimated to be $910,876 including $544,700 in EECBG funds and $366,176 in leveraged funds.... Show more | Energy Department | 9/11/2009 | ||||||||||||||||||||||||
| MULTIPLE RECIPIENTS | $542,896.00 | Loan | Very Low to Moderate Income Housing Loans - Guaranteed Single Family Housing Guaranteed Loans - ARRA | Agriculture Department / Rural Housing Service | |||||||||||||||||||||||||
| CHEEKTOWAGA-SLOAN UNION FREE SCHOOL DISTRICT INC | $541,805.00 | Grant |
State Fiscal Stabilization Fund (SFSF) - Education State Grants, Recovery Act For the support of public elementary, secondary, and post secondary education and, as, applicable early childhood education programs and services
This spending item is part of a $1,653,930,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 5/08/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $539,086.00 | Grant | Trans-NSF Recovery Act Reasearch Support From representation to learning to inference, effective use of high-level semantic knowledge in computer vision remains a challenge in bridging the signal-symbol gap. This research investigates the role of semantics in visual inference through the generalized image understanding problem: to automatically detect, localize, segment, and recognize the core high-level elements and how they interact in an image, and provide a parsimonious semantic description of the image. Specifically, this research examines a unified methodology that integrates low- (e.g., pixels and features), mid- (e.g. latent structure), and high-level (e.g., semantics) elements for visual inference. Adaptive graph hierarchies induced directly from the images provide the core mathematical representation. A statistical interpretation of affinities between neighboring pixels and regions in the image drives this induction. Latent elements and structure are captured with multilevel Markov networks. A probabilistic ontology represents the core knowledge and uncertainty of the inferred structure and guides the ultimate semantic interpretation of the image. At each level, rigorous methods from computer science and statistics are connected to and combined with formal semantic methods from philosophy. A symbiotic education plan involving graduate and undergraduate mentoring and education, professional tutorial courses at the boundary of vision and ontology, and K-12 outreach is incorporated into the research plan. The research and education, disseminated broadly through both the applied science and semantics/philosophy literatures, lays a foundation on which to both utilize and automatically extract rich semantic information from images and other signal data for critical application areas such as internet vision, autonomous navigation, and ambient biometrics.... Show more | National Science Foundation | 6/26/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $539,086.00 | Grant | Trans-NSF Recovery Act Reasearch Support From representation to learning to inference, effective use of high-level semantic knowledge in computer vision remains a challenge in bridging the signal-symbol gap. This research investigates the role of semantics in visual inference through the generalized image understanding problem: to automatically detect, localize, segment, and recognize the core high-level elements and how they interact in an image, and provide a parsimonious semantic description of the image. Specifically, this research examines a unified methodology that integrates low- (e.g., pixels and features), mid- (e.g. latent structure), and high-level (e.g., semantics) elements for visual inference. Adaptive graph hierarchies induced directly from the images provide the core mathematical representation. A statistical interpretation of affinities between neighboring pixels and regions in the image drives this induction. Latent elements and structure are captured with multilevel Markov networks. A probabilistic ontology represents the core knowledge and uncertainty of the inferred structure and guides the ultimate semantic interpretation of the image. At each level, rigorous methods from computer science and statistics are connected to and combined with formal semantic methods from philosophy. A symbiotic education plan involving graduate and undergraduate mentoring and education, professional tutorial courses at the boundary of vision and ontology, and K-12 outreach is incorporated into the research plan. The research and education, disseminated broadly through both the applied science and semantics/philosophy literatures, lays a foundation on which to both utilize and automatically extract rich semantic information from images and other signal data for critical application areas such as internet vision, autonomous navigation, and ambient biometrics.... Show more | National Science Foundation | 6/26/2009 | ||||||||||||||||||||||||
| COMMUNITY HEALTH CENTER OF BUFFALO, INC. | $535,880.00 | Grant | ARRA ? Health Center Integrated Services Development Initiative[g1] ARRA ? Capital Improvement Program: CIP funds will be used to underwrite part of the cost of constructing a 36,000 sq. ft. building to allow the Community Health Center of Buffalo, Inc. (CHCB) to increase access to care for underservved populations. The CHCB building will have two floors and a 150-car surface parking lot. Phase 1, to be completed using CIP funds, includes 24,000 sq. ft. On the first floor will be a waiting room, exam rooms, procedure rooms, social work, a 340 pharmacy, and the billing department (Phase 1). Administrative offices will be on the second floor. The CHCB?s number of medical exam rooms will increase from 16 to 21. A main entrance and separate access points are planned for staff and for service/loading. The building will have two elevators and will be fully handicap accessible. The impact of the CHCB serving as a primary care hub for Buffalo will be to improve access of the medically underserved to high quality, comprehensive and culturally sensitive primary care, including appropriate specialty services. Construction of a new primary care facility offers the opportunity to develop collaborative services between the CHCB and major hospital systems in Buffalo, NY. The CHCB will act as the ?hub? or entry point to the health care delivery system in Buffalo. Collaborative agreements link CHCB to hospitals and specialists into a mutually beneficial network that reduces barriers to accessing care. The CHCB will work towards an integrated health care delivery system designed to: 1) improve the effectiveness of primary care services; 2) reduce the overall health care costs; 3) broaden access to services; and 4) improve targeting services to identified health problems in the community. Using health information technology, the CHCB will become more data driven to improve individual patient care and operational efficiencies. There will be increased access to comprehensive care management because the CHCB approach integrates a continuum of services (outreach, risk assessment, education, prevention, medical care, social support and follow-up) to improve community wellness. There will be 5 FTE health care jobs created. There will be 27 FTE construction jobs created. The Project Team is headed by Dr. LaVonne Ansari. She has more than 20 years of combined experience in workforce development and business administration, health care, higher education, and EEO/affirmative action compliance. Richard T. Pope, CPA, is the Financial Director and Chief Financial Officer for CHCB. He is a graduate of State University of New York at Buffalo with a B.S. Degree in Business Management. Employment history reflects 20 years of financial experience. The CHCB governing board has unanimously approved this project and is committed to this expansion of services. Stievater + Associates: architects has over 20 years medical design experience, including about 50 projects over the last 15 years. Casilio Companies will provide construction management. Since its founding, the Casilio Companies has developed over 20 million sq. ft. of space. Construction Management and general construction projects include medical surgical units and corporate offices. The CHCB will conduct outreach to the disconnected and unconnected medically underserved individuals and special needs populations. The CHCB envisions the new location as a gateway for a wide spectrum of activities that promote wellness.... Show more | Health and Human Services, Department of / Health Resources and Services Administration | 6/25/2009 | ||||||||||||||||||||||||
| COMMUNITY HEALTH CENTER OF BUFFALO, INC. | $535,880.00 | Grant | ARRA ? Health Center Integrated Services Development Initiative[g1] ARRA ? Capital Improvement Program: CIP funds will be used to underwrite part of the cost of constructing a 36,000 sq. ft. building to allow the Community Health Center of Buffalo, Inc. (CHCB) to increase access to care for underservved populations. The CHCB building will have two floors and a 150-car surface parking lot. Phase 1, to be completed using CIP funds, includes 24,000 sq. ft. On the first floor will be a waiting room, exam rooms, procedure rooms, social work, a 340 pharmacy, and the billing department (Phase 1). Administrative offices will be on the second floor. The CHCB?s number of medical exam rooms will increase from 16 to 21. A main entrance and separate access points are planned for staff and for service/loading. The building will have two elevators and will be fully handicap accessible. The impact of the CHCB serving as a primary care hub for Buffalo will be to improve access of the medically underserved to high quality, comprehensive and culturally sensitive primary care, including appropriate specialty services. Construction of a new primary care facility offers the opportunity to develop collaborative services between the CHCB and major hospital systems in Buffalo, NY. The CHCB will act as the ?hub? or entry point to the health care delivery system in Buffalo. Collaborative agreements link CHCB to hospitals and specialists into a mutually beneficial network that reduces barriers to accessing care. The CHCB will work towards an integrated health care delivery system designed to: 1) improve the effectiveness of primary care services; 2) reduce the overall health care costs; 3) broaden access to services; and 4) improve targeting services to identified health problems in the community. Using health information technology, the CHCB will become more data driven to improve individual patient care and operational efficiencies. There will be increased access to comprehensive care management because the CHCB approach integrates a continuum of services (outreach, risk assessment, education, prevention, medical care, social support and follow-up) to improve community wellness. There will be 5 FTE health care jobs created. There will be 27 FTE construction jobs created. The Project Team is headed by Dr. LaVonne Ansari. She has more than 20 years of combined experience in workforce development and business administration, health care, higher education, and EEO/affirmative action compliance. Richard T. Pope, CPA, is the Financial Director and Chief Financial Officer for CHCB. He is a graduate of State University of New York at Buffalo with a B.S. Degree in Business Management. Employment history reflects 20 years of financial experience. The CHCB governing board has unanimously approved this project and is committed to this expansion of services. Stievater + Associates: architects has over 20 years medical design experience, including about 50 projects over the last 15 years. Casilio Companies will provide construction management. Since its founding, the Casilio Companies has developed over 20 million sq. ft. of space. Construction Management and general construction projects include medical surgical units and corporate offices. The CHCB will conduct outreach to the disconnected and unconnected medically underserved individuals and special needs populations. The CHCB envisions the new location as a gateway for a wide spectrum of activities that promote wellness.... Show more | Health and Human Services, Department of / Health Resources and Services Administration | 6/25/2009 | ||||||||||||||||||||||||
| Winning Smiles Pediatric Dentistry, PLLC | $535,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $533,041.00 | Grant | Trans-NSF Recovery Act Reasearch Support The sense of taste is used by all organisms to determine whether potential food items will be ingested or rejected and is critical for the survival of the organism. The taste system is made up of multiple cell types that detect chemicals in food and then send a specific signal describing that stimulus to the brain. The goal of this project is to characterize a newly identified signaling pathway in taste cells that contributes to the detection of taste stimuli. Characterization of this signaling pathway will provide a better understanding of how the taste system works and how the brain gathers information about its surroundings. A combination of calcium imaging, molecular biology, and immunocytochemistry will be used to describe this newly identified signaling pathway and define its physiological role in the formation of taste signals that are sent to the brain. The findings that emerge from this project will improve the understanding of how taste receptor cells that are located on the tongue can detect chemicals in food and translate that information into a signal that the brain can understand. This information is critical for two reasons: 1) understanding how chemicals are detected from the environment has important implications in feeding behaviors including the regulation of food intake, and 2) information about the physiology of these neuronal cells will translate into a better understanding of how signaling pathways function in all neurons. This project will provide research and training opportunities for multiple graduate and undergraduate students, including both minorities and women. Students will be trained in molecular biology and immunocytochemical techniques as well as live cell calcium imaging on taste cells. These skills will provide students with the ability to answer research questions (either in the taste field or elsewhere) using a multi-faceted approach.... Show more | National Science Foundation | 6/01/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $533,041.00 | Grant | Trans-NSF Recovery Act Reasearch Support The sense of taste is used by all organisms to determine whether potential food items will be ingested or rejected and is critical for the survival of the organism. The taste system is made up of multiple cell types that detect chemicals in food and then send a specific signal describing that stimulus to the brain. The goal of this project is to characterize a newly identified signaling pathway in taste cells that contributes to the detection of taste stimuli. Characterization of this signaling pathway will provide a better understanding of how the taste system works and how the brain gathers information about its surroundings. A combination of calcium imaging, molecular biology, and immunocytochemistry will be used to describe this newly identified signaling pathway and define its physiological role in the formation of taste signals that are sent to the brain. The findings that emerge from this project will improve the understanding of how taste receptor cells that are located on the tongue can detect chemicals in food and translate that information into a signal that the brain can understand. This information is critical for two reasons: 1) understanding how chemicals are detected from the environment has important implications in feeding behaviors including the regulation of food intake, and 2) information about the physiology of these neuronal cells will translate into a better understanding of how signaling pathways function in all neurons. This project will provide research and training opportunities for multiple graduate and undergraduate students, including both minorities and women. Students will be trained in molecular biology and immunocytochemical techniques as well as live cell calcium imaging on taste cells. These skills will provide students with the ability to answer research questions (either in the taste field or elsewhere) using a multi-faceted approach.... Show more | National Science Foundation | 6/01/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $525,000.00 | Grant | Trans-NSF Recovery Act Reasearch Support Technical Abstract This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This Faculty Early Career Award funds a proposal that seeks to make significant impact on our current understanding of the physics of quantum phase transitions (QPT) in superconducting nanostructures. Nanometer scale indium oxide devices with precisely engineered structural and transport characteristics will be utilized to probe the subtle interplay between disorder and interaction across the superconductor-insulator QPT. These experiments will provide explicit information about the microscopic conduction mechanisms when the transition is tuned via disorder, density or magnetic field in one and two-dimensional devices. The results will improve our current understanding of the phase coherence and emergence of novel collective phases near quantum critical points. Research is closely integrated with the education component of the proposal: an undergraduate laboratory experiment to explore quantum nature of electrons will be developed and hands-on research opportunities will be provided to a broader group including high school science teachers in the Buffalo region. The education plan also seeks to improve the learning experience of students in undergraduate introductory physics courses through a variety of modern teaching methods. Non-technical Abstract: This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The goal of this Faculty Early Career Award is to effectively combine experimental research to explore quantum phases near critical points in superconducting nanostructures with education and outreach programs to train a new generation of undergraduate and graduate students and high school teachers. The research proposal will seek an unprecedented control in engineering the microstructure and property of the material used (indium oxide) and the transport measurements in nanodevices proposed herein are expected to transform our current understanding of quantum phases in one and two-dimensional systems. The integrated educational aspects will involve several projects closely related to the research activities in the PI?s group. A new undergraduate laboratory experiment for learning the basic concept of quantum nature of electrons will be developed with the help of undergraduate students at the university or K-12 physics teachers in the Buffalo region. Modern teaching methods will be implemented in introductory physics courses for non-majors, thereby improving the learning experience and scientific awareness among a wider student body. The results of the research and educational activities will be disseminated to the general public through participation in local art festivals and New York State?s STEP program... Show more | National Science Foundation | 8/19/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $525,000.00 | Grant | Trans-NSF Recovery Act Reasearch Support Technical Abstract-á This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This Faculty Early Career Award funds a proposal that seeks to make significant impact on our current understanding of the physics of quantumm phase transitions (QPT) in superconducting nanostructures. Nanometer scale indium oxide devices with precisely engineered structural and transport characteristics will be utilized to probe the subtle interplay between disorder and interaction across the superconductor-insulator QPT. These experiments will provide explicit information about the microscopic conduction mechanisms when the transition is tuned via disorder, density or magnetic field in one and two-dimensional devices. The results will improve our current understanding of the phase coherence and emergence of novel collective phases near quantum critical points. Research is closely integrated with the education component of the proposal: an undergraduate laboratory experiment to explore quantum nature of electrons will be developed and hands-on research opportunities will be provided to a broader group including high school science teachers in the Buffalo region. The education plan also seeks to improve the learning experience of students in undergraduate introductory physics courses through a variety of modern teaching methods.-á Non-technical Abstract: This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The goal of this Faculty Early Career Award is to effectively combine experimental research to explore quantum phases near critical points in superconducting nanostructures with education and outreach programs to train a new generation of undergraduate and graduate students and high school teachers. The research proposal will seek an unprecedented control in engineering the microstructure and property of the material used (indium oxide) and the transport measurements in nanodevices proposed herein are expected to transform our current understanding of quantum phases in one and two-dimensional systems. The integrated educational aspects will involve several projects closely related to the research activities in the PIs group. A new undergraduate laboratory experiment for learning the basic concept of quantum nature of electrons will be developed with the help of undergraduate students at the university or K-12 physics teachers in the Buffalo region. Modern teaching methods will be implemented in introductory physics courses for non-majors, thereby improving the learning experience and scientific awareness among a wider student body. The results of the research and educational activities will be disseminated to the general public through participation in local art festivals and New York States STEP program... Show more | National Science Foundation | 8/19/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $524,049.00 | Grant | Trans-NSF Recovery Act Reasearch Support The State University of New York at Buffalo has received a grant to create a database and software tools to facilitate the study of gene regulation, through transcriptional cis-regulatory modules (CRMs). CRMs are a major class of genomic sequence elements requuired for the temporal and spatial control of gene expression. CRMs play critical roles with respect to normal phenotypic variation, birth defects, chronic diseases, and evolution. Despite this clear importance of CRMs for many areas of biology, our knowledge of these sequences is surprisingly limited. CRMs are vastly underrepresented in current genome annotations, in part because most CRMs are uncharacterized, but also because there has been little effort to curate the literature for known CRMs or to develop appropriate databases to house CRM information. This project, by producing a well-annotated collection of known CRMs, will be of significant use in a number of important areas, including studies of transcriptional regulation, of the evolution of CRMs and new gene functions, and of genome structure. The project also provides training data for computational approaches to CRM discovery, leading to improved methods for identifying uncharacterized CRMs. The project has constructed the first database of known CRMs for any animal, the REDfly (Regulatory Element Database for Fly) database of regulatory elements for the fruit fly Drosophila melanogaster. Funding under this award is allowing for the continued development and expansion of REDfly into a fully comprehensive resource for Drosophila and for its extension to regulatory elements from vertebrate model organisms, including the zebrafish and mouse. Analysis of the REDfly data will lead to the discovery of new important features of CRMs and to the generation of exciting new hypotheses about gene regulation that are being tested experimentally in the laboratory. REDfly also serves as a useful resource for education and training in genomics, gene regulation, and genome annotation at the graduate, undergraduate, and secondary school levels through a variety of courses, workshops, and informal training activities. These activities create in REDfly a comprehensive repository for cis-regulatory sequence and expression pattern data for three major metazoan model organisms, making REDfly the most powerful available resource for large-scale studies of the composition, organization, and evolution of transcriptional cis-regulatory elements. The REDfly database can be found at http://redfly.ccr.buffalo.edu.... Show more | National Science Foundation | 7/18/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $524,049.00 | Grant | Trans-NSF Recovery Act Reasearch Support The State University of New York at Buffalo has received a grant to create a database and software tools to facilitate the study of gene regulation, through transcriptional cis-regulatory modules (CRMs). CRMs are a major class of genomic sequence elements requuired for the temporal and spatial control of gene expression. CRMs play critical roles with respect to normal phenotypic variation, birth defects, chronic diseases, and evolution. Despite this clear importance of CRMs for many areas of biology, our knowledge of these sequences is surprisingly limited. CRMs are vastly underrepresented in current genome annotations, in part because most CRMs are uncharacterized, but also because there has been little effort to curate the literature for known CRMs or to develop appropriate databases to house CRM information. This project, by producing a well-annotated collection of known CRMs, will be of significant use in a number of important areas, including studies of transcriptional regulation, of the evolution of CRMs and new gene functions, and of genome structure. The project also provides training data for computational approaches to CRM discovery, leading to improved methods for identifying uncharacterized CRMs. The project has constructed the first database of known CRMs for any animal, the REDfly (Regulatory Element Database for Fly) database of regulatory elements for the fruit fly Drosophila melanogaster. Funding under this award is allowing for the continued development and expansion of REDfly into a fully comprehensive resource for Drosophila and for its extension to regulatory elements from vertebrate model organisms, including the zebrafish and mouse. Analysis of the REDfly data will lead to the discovery of new important features of CRMs and to the generation of exciting new hypotheses about gene regulation that are being tested experimentally in the laboratory. REDfly also serves as a useful resource for education and training in genomics, gene regulation, and genome annotation at the graduate, undergraduate, and secondary school levels through a variety of courses, workshops, and informal training activities. These activities create in REDfly a comprehensive repository for cis-regulatory sequence and expression pattern data for three major metazoan model organisms, making REDfly the most powerful available resource for large-scale studies of the composition, organization, and evolution of transcriptional cis-regulatory elements. The REDfly database can be found at http://redfly.ccr.buffalo.edu.... Show more | National Science Foundation | 7/18/2009 | ||||||||||||||||||||||||
| FREY ELECTRIC CONSTRUCTION CO., INC. | $517,250.00 | Contract |
furnish all labor, materials, equipment, etc. necessary for our project called RENOVATE WARD 9A at the VA Medical Center
This spending item is part of a $3,186,390.00 allocation. See details |
Department of Veterans Affairs | 5/13/2009 | ||||||||||||||||||||||||
| FREY ELECTRIC CONSTRUCTION CO., INC. | $517,250.00 | Contract |
Provide all labor, materials , tools and equipment necessary for our project at the VA Western New York Healthcare System, Buffalo NY.
This spending item is part of a $3,186,390.00 allocation. See details |
Department of Veterans Affairs | 5/13/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $509,940.00 | Grant |
Trans-NIH Recovery Act Research Support Chronic disease is a major contributor to health disparities, and complex chronic disease (multiple chronic conditions requiring multiple providers) is increasingly common. Literature suggests that individuals with chronic disease receive less preventive cancerr screening than individuals without a chronic disease, but little research is available to assess the incorporation of preventive cancer screening among patients with complex chronic disease (CCD). For minority populations with limited resources and disproportionate rates of some chronic conditions, this may contribute to poorer outcomes and greater disparities. This study will build upon a well established partnership of university and community collaborators to assess barriers to and motivators for preventive cancer screening and will design a patient-driven intervention to incorporate cancer screening into chronic disease management. The Community Based Participatory Research (CBPR) team will be jointly led by 2 PIs, one from the community and one from a university. A CBPR Steering Committee will include 4 researchers from a School of Medicine, a School of Public Health, and a Cancer Research Institute, 2 community-based organizations, 2 primary care practices serving predominantly minority low- income patients, and a Patient Action Team of patients with CCD. The study aims are to: (1) conduct a cross-sectional study to describe cancer prevention screening among patients with CCD; (2) design a pilot cancer-prevention intervention with a Patient Action Team (composed of patients with CCD) based on patient-reported factors that enable or hinder cancer prevention screening among adults with CCD in low- income, minority communities; and (3) conduct a pilot cancer-prevention intervention among patients with CCD in preparation for a larger CBPR Roll study. Specifically, this study will develop a registry of patients with complex chronic disease from 2 community medical practices. The registry will be used to: (a) conduct a descriptive cross-sectional study to explore disparities in cancer prevention screening (Aim 1); (b) recruit patients with CCD to serve on a Patient Action Team to design an intervention (Aim 2); and (c) recruit patients with CCD to pilot test the patient-centered intervention (Aim 3). RELEVANCE (See instructions): The prevalence of adults with multiple chronic diseases is increasing. This proposal will establish a university-community partnership to engage patients with complex chronic disease living in predominately minority low-income communities to collaborate in developing an intervention to improve cancer prevention screening. The intervention will be based on patient perceptions of need, priority, barriers, and motivators to include preventive cancer screening as part of their patient-centered care regimen.... Show more
This spending item is part of a $535,271.00 allocation. See details |
Health and Human Services, Department of / National Institutes of Health | 9/21/2009 | ||||||||||||||||||||||||
| TRANSPORTATION, NEW YORK DEPARTMENT OF | $500,000.00 | Grant | Highway Planning and Construction Highway Infrastructure Investment Grant: Available for Use in Any Area (flexible) | Transportation Department / Federal Highway Administration | 4/29/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $499,995.00 | Grant | Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (04) Clinical Research and specific Challenge Topic, 04- AA-103: Novel Models of Service Delivery. Nearly 1 in 20 adult women in the U.S. are married to or living with an alcoholic or problem drinking partner. As a result, these individuals experience significant psychological and physical distress, utilize health care services to a greater degree than spouses of nonalcoholics, and incur overall higher healthcare costs. While their physical and psychological health is important in its own right, their health and coping skills also can play a significant role in facilitating alcoholic partner drinking reduction and help-seeking, and in buffering their children from the negative effects of the other parent's alcohol problem. Yet, despite its size, distress, and importance, this population remains largely hidden and underserved. Relatively few of their partners seek treatment, and psychological and socioeconomic barriers limit the availability of and access to empirically- tested services for themselves. These barriers include: (a) inadequate third party coverage, (b) inability to pay, (c) fear of stigmatization, (d) fear of the partner's reaction, (e) competing job, childcare and other demands, (f) geographical and other isolation, and (g) the fear that they will be told to leave the partner, which they are not willing to do. The self-help group Al-Anon is available to this group, but not widely used, and its efficacy unclear. Stage II efficacy trials now show that clinic-based cognitive-behavioral, coping skill-based interventions, designed specifically for the spouse of the alcoholic can be effective in reducing psychological distress or facilitating alcoholic-partner help-seeking or drinking reduction, but the access barriers remain the same. Unless alternate service delivery models are developed, these treatments will reach relatively few individuals, and have little public health impact. The challenge is to develop novel, alternate service delivery models for these empirically-supported interventions that provide secure, engaging, low cost, easy access to a much larger population of women with alcoholic partners than the small population currently served. To begin to address this service delivery challenge, the current Stage I treatment development application proposes to build on the investigators' substantial research on face-to-face Coping Skills Training (CST) for women with alcoholic partners by adapting CST to a World Wide Web-accessible or deliverable database. An internet-delivered CST model has the potential to address several of the barriers noted above by providing services that (a) are relatively low cost, (b) readily accessible to a very broad population of women with alcoholic partners, (c) are accessible 24/7, and (d) with appropriate security precautions, offer a higher degree of privacy than clinic-based treatment, thereby helping to reduce stigma, embarrassment and other concerns. Development and preliminary evaluation of the internet-based CST (iCST) in the current proposal is accomplished in the two substages of Stage I treatment development work. In Stage Ia, we follow an iterative, user-centered Web site development process to adapt the content of the previously developed, face-to-face CST for interactive, on-line delivery. In Stage Ib, we pilot the feasibility of recruiting women for an iCST clinical trial, and randomly assign 84 women with a partner with an active alcohol use disorder to either 8 weeks of iCST or 8 weeks of a delayed treatment control (DTC) condition. The complete abstract for this award is available at http://report.nih.gov/recovery/... Show more | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 | ||||||||||||||||||||||||
| Advan-Tech Acquisition Inc. | $493,400.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| HEALTH RESEARCH, INC. | $491,634.00 | Grant | Trans-NIH Recovery Act Research Support To obtain a detailed understanding of both innate and adaptive immune responses to bacterial pathogens that cause repeated respiratory tract infections in chronic obstructive pulmonary disease (COPD) patients. We are studying how key outer membrane antigens of the bacteria that are responsible for exacerbations of COPD stimulate innate and adaptive immune responses and how their cross-talk accounts for some of the lung damage that is manifested during the disease. An understanding of these processes will be crucial to the strategies to vaccine development and patient management.... Show more | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 | ||||||||||||||||||||||||
| TRANSPORTATION, NEW YORK DEPARTMENT OF | $491,210.00 | Grant | Highway Planning and Construction Highway Infrastructure Investment Grant: Available for Use in Any Area (flexible) | Transportation Department / Federal Highway Administration | 6/02/2009 | ||||||||||||||||||||||||
| O'Connell Electric Company, Inc. | $490,000.00 | Contract |
WHOLE NAVAL OPERTIONAL SUPPORT CENTER MODERNIZATION , ERIE PA. WORK TO INCLUDE; NEW BOILER AND HOT WATER HEATING SYSTEM, NEW ROOF-TOP HVAC UNITS, NEW EPDM ROOFING SYSTEM, NEW DIRECT DIGITAL CONTROLS SYSTEM, NEW INTERIOR LIGHTING, NEW EXTERIOR SITE LIGHTING, NEW FIRE PROTECTION SPRINKLER SYSTEM, NEWW FIRE ALARM AND MASS NOTIFICATION SYSTEM, NEW ELECTRIC SECURITY SYSTEM, UPGRADED INTERIOR ELECTRICAL WORK, NEW CERAMIC TILE FLOORING AND WALLS IN LAVATORIES AND SHOWER/LOCKER ROOMS, NEW RESILIENT FLOORING, NEW ATHLETIC FLOORING, NEW CARPET, NEW PAINT, NEW ACOUSTICAL CEILING SYSTEMS, NEW GUARD SHACK AT THE MAIN GATE ENTRANCE, NEW SECURITY FENCE AROUND THE PERIMETER OF THE PROPERTY AND ENTRANCE GATE, AND NEW TRUCK LIFT.... Show more
This spending item is part of a $4,403,000.00 allocation. See details |
Navy | 9/30/2009 | ||||||||||||||||||||||||
| WEST SENECA CENTRAL SCHOOL DISTRICT | $488,955.00 | Grant |
Title I Grants to Local Educational Agencies, Recovery Act Improve teaching and learning for students most at risk of failing to meet State academic achievement standards
This spending item is part of a $907,152,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 4/01/2009 | ||||||||||||||||||||||||
| TRANSPORTATION, NEW YORK DEPARTMENT OF | $481,358.00 | Grant | Highway Planning and Construction Highway Infrastructure Investment Grant: Available for Use in Any Area (flexible) | Transportation Department / Federal Highway Administration | 4/29/2009 | ||||||||||||||||||||||||
| SWEET HOME CENTRAL SCHOOL DISTRICT | $479,699.00 | Grant |
Special Education Grants to States, Recovery Act Assist States in providing special education and related services to children with disabilities in accordance with Part B of the IDEA
This spending item is part of a $759,193,000.00 allocation. See details |
Education Department / Office of Special Education and Rehabilitative Services | 4/01/2009 | ||||||||||||||||||||||||
| ARSENAL CONTRACTING LLC | $472,000.00 | Contract |
Replace HVAC System in Bldg 92
This spending item is part of a $1,875,000.00 allocation. See details |
Department of Veterans Affairs | 9/28/2009 | ||||||||||||||||||||||||
| Brown and Jones Medical Group, P.C. | $466,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| HAMBURG CENTRAL SCHOOL SYSTEM | $461,925.00 | Grant |
Special Education Grants to States, Recovery Act Assist States in providing special education and related services to children with disabilities in accordance with Part B of the IDEA
This spending item is part of a $759,193,000.00 allocation. See details |
Education Department / Office of Special Education and Rehabilitative Services | 4/01/2009 | ||||||||||||||||||||||||
| Tammy M E Perison, DDS | $461,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| ALLIANCE CONTRACTING, LLC | $459,980.00 | Contract |
Abatement/Demolition of buildings 6, 7, 11, and 35 at Samual S. Strattion VA in Albany
This spending item is part of a $500,180.00 allocation. See details |
Department of Veterans Affairs | 6/30/2009 | ||||||||||||||||||||||||
| CLEVELAND BIOLABS, INC. | $458,512.00 | Grant | Trans-NIH Recovery Act Research Support To develop a medical radiation countermeasure to meet the radiological and nuclear threats in support of the preparedness mission and priorities of the HHS Puclic Health Emergency Medical Countermeasures Enterprise (PHEMCE) as articulated in the PHEMCE Implemenntation Plan for CBRN threats. (page 3) ... Show more | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 | ||||||||||||||||||||||||
| AMHERST C H S SCH DIST 1 | $452,432.00 | Grant |
Special Education Grants to States, Recovery Act Assist States in providing special education and related services to children with disabilities in accordance with Part B of the IDEA
This spending item is part of a $759,193,000.00 allocation. See details |
Education Department / Office of Special Education and Rehabilitative Services | 4/01/2009 | ||||||||||||||||||||||||
| WBG Enterprises, Inc. | $450,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| TRANSPORTATION, NEW YORK DEPARTMENT OF | $447,857.00 | Grant | Highway Planning and Construction Highway Infrastructure Investment Grant: Available for Use in Any Area (flexible) | Transportation Department / Federal Highway Administration | 4/29/2009 | ||||||||||||||||||||||||
| MULTIPLE RECIPIENTS | $442,162.00 | Loan | Very Low to Moderate Income Housing Loans - Guaranteed Single Family Housing Guaranteed Loans - ARRA | Agriculture Department / Rural Housing Service | |||||||||||||||||||||||||
| GENESIS CHIROPRACTIC | $440,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| INSTALLS INC, LLC | $440,000.00 | Contract | Basic In-home Digital converter box installation in AL, FL, GA, MS, NC, SC, TN and VA. Installed 5,317 boxes. | Federal Communications Commission | 5/02/2009 | ||||||||||||||||||||||||
| BRYANT & STRATTON COLLEGE INC | $439,979.00 | Grant | Federal Pell Grant Program GRANT PROGRAM | Education Department / DOED - Student Financial Assistance Programs | |||||||||||||||||||||||||
| HILBERT COLLEGE | $438,948.00 | Grant | Federal Pell Grant Program GRANT PROGRAM | Education Department / DOED - Student Financial Assistance Programs | |||||||||||||||||||||||||
| MULTIPLE RECIPIENTS | $429,382.00 | Loan | Very Low to Moderate Income Housing Loans - Guaranteed Single Family Housing Guaranteed Loans - ARRA | Agriculture Department / Rural Housing Service | |||||||||||||||||||||||||
| INSTALLS INC, LLC | $420,000.00 | Contract | Basic In-home Digital converter box installation in AR, LA, OK and TX. Installed 4,836 boxes. | Federal Communications Commission | 5/02/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $410,442.00 | Grant | Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (01) Behavior, Behavioral Change, and Prevention and specific Challenge Topic, 01-GM-104: Mechanisms of Behavior Change Research. Cognitive-behavioral therapy (CBT) is well-established as an effective treatment foor alcohol dependence. However, many of the pretreatment-posttreatment designs used to study CBT, while important in answering questions about if a treatment works, provide much less information about how CBT works. In recent years, there has been a resurgence of interest in studying what happens between the pretreatment and posttreatment assessment- the process of change-and a renewed understanding of the important role of this research in treatment development (Hayes, Hope, & Hayes, 2007). A central mechanism of CBT is the acquisition and use of coping skills. However, in a review of 10 studies that tested coping as a hypothesized mechanism of action of CBT, Morganstern and Longabuagh (2000) concluded that there is no support for the hypothesis that CBT works through its effects on coping. Although several possible mechanisms have been proposed to explain the effects of CBT, it is rare that more than one mechanism is studied. According to Kazdin (2007), the assessment of multiple mediators (viz. mechanisms) in a given study has enormous benefits. If two or more mechanisms are studied, one can identify if one is more plausible or makes a greater contribution to the outcome. In addition, the assessment of multiple potential mechanisms is cost efficient, given the amount of time and resources needed for any one treatment outcome study. Across many studies, some mechanisms may repeatedly emerge as possible contenders while others fall by the wayside. In addition to coping skills, two key mechanisms posited to underlie the effectiveness of CBT are increasing self-efficacy and self- confidence and reducing positive outcome expectancies for alcohol use (Moos, 2007). Two other mechanisms, thought to be operating across many different interventions, including CBT, are increasing the therapeutic alliance and reducing/regulating negative emotional states. For the present study, participants will be 72 alcohol dependent men and women who agree to participate in a 12-week trial of CBT for alcohol dependence. In addition, comprehensive research assessments will be conducted with patients at baseline, end of treatment, and 3-months posttreatment. The overarching goal of the present study is to map the process of change in successful CBT by measuring the aforementioned 4 theoretically relevant behavioral mechanisms of change on multiple (i.e., weekly) occasions during treatment. As Hayes et al. (2007) state, such a 'map' would have several important implications, including, (1) further refinement of existing treatment procedures; (2) a clearer picture of the processes of recovery, treatment dropout, poor response, and relapse; and (3) further development of empirically supported treatment processes. Although several possible mechanisms have been proposed to explain the effects of CBT, it is rare that more than one mechanism is studied. The goal of the present study is to map the process of change in successful CBT by measuring 4 theoretically relevant behavioral mechanisms of change on multiple occasions during treatment (i.e., following weekly treatment sessions). Such a fine-grained analysis is needed in order to study the unfolding of processes over time. Such a 'map' would have several important implications, including, (1) further refinement of existing treatment procedures; (2) a clearer picture of the processes of recovery, treatment dropout, poor response, and relapse; and (3) further development of empirically supported treatment processes.... Show more | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $410,442.00 | Grant | Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (01) Behavior, Behavioral Change, and Prevention and specific Challenge Topic, 01-GM-104: Mechanisms of Behavior Change Research. Cognitive-behavioral therapy (CBT) is well-established as an effective treatment foor alcohol dependence. However, many of the pretreatment-posttreatment designs used to study CBT, while important in answering questions about if a treatment works, provide much less information about how CBT works. In recent years, there has been a resurgence of interest in studying what happens between the pretreatment and posttreatment assessment- the process of change-and a renewed understanding of the important role of this research in treatment development (Hayes, Hope, & Hayes, 2007). A central mechanism of CBT is the acquisition and use of coping skills. However, in a review of 10 studies that tested coping as a hypothesized mechanism of action of CBT, Morganstern and Longabuagh (2000) concluded that there is no support for the hypothesis that CBT works through its effects on coping. Although several possible mechanisms have been proposed to explain the effects of CBT, it is rare that more than one mechanism is studied. According to Kazdin (2007), the assessment of multiple mediators (viz. mechanisms) in a given study has enormous benefits. If two or more mechanisms are studied, one can identify if one is more plausible or makes a greater contribution to the outcome. In addition, the assessment of multiple potential mechanisms is cost efficient, given the amount of time and resources needed for any one treatment outcome study. Across many studies, some mechanisms may repeatedly emerge as possible contenders while others fall by the wayside. In addition to coping skills, two key mechanisms posited to underlie the effectiveness of CBT are increasing self-efficacy and self- confidence and reducing positive outcome expectancies for alcohol use (Moos, 2007). Two other mechanisms, thought to be operating across many different interventions, including CBT, are increasing the therapeutic alliance and reducing/regulating negative emotional states. For the present study, participants will be 72 alcohol dependent men and women who agree to participate in a 12-week trial of CBT for alcohol dependence. In addition, comprehensive research assessments will be conducted with patients at baseline, end of treatment, and 3-months posttreatment. The overarching goal of the present study is to map the process of change in successful CBT by measuring the aforementioned 4 theoretically relevant behavioral mechanisms of change on multiple (i.e., weekly) occasions during treatment. As Hayes et al. (2007) state, such a 'map' would have several important implications, including, (1) further refinement of existing treatment procedures; (2) a clearer picture of the processes of recovery, treatment dropout, poor response, and relapse; and (3) further development of empirically supported treatment processes. Although several possible mechanisms have been proposed to explain the effects of CBT, it is rare that more than one mechanism is studied. The goal of the present study is to map the process of change in successful CBT by measuring 4 theoretically relevant behavioral mechanisms of change on multiple occasions during treatment (i.e., following weekly treatment sessions). Such a fine-grained analysis is needed in order to study the unfolding of processes over time. Such a 'map' would have several important implications, including, (1) further refinement of existing treatment procedures; (2) a clearer picture of the processes of recovery, treatment dropout, poor response, and relapse; and (3) further development of empirically supported treatment processes.... Show more | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 | ||||||||||||||||||||||||
| NIAGARA FRONTIER TRANSPORTATION AUTHORITY | $409,946.00 | Grant | Federal Transit_Capital Investment Grants The purpose of this grant is to invest in public transportation by upgrading the Niagara Frontier Transportation Authority (NFTA) Metro Rail's power support system. NY-56-0002-00 entails the purchase of Uninterruptible Power Supply (UPS) Batteries and Tractioon Power Substation Batteries for the 6.2 mile rail line in Buffalo, New York.... Show more | Transportation Department / Federal Transit Administration | 8/21/2009 | ||||||||||||||||||||||||
| INSTALLS INC, LLC | $400,000.00 | Contract | Basic In-home Digital converter box installation in AZ, CA, NV, OR, UT and WA. Installed 3,010 boxes. | Federal Communications Commission | 5/02/2009 | ||||||||||||||||||||||||
| Michael J. Garvey, DMD | $400,000.00 | Loan | 7(a) Loan Guarantees PATRIOT EXPRESS | Small Business Administration | |||||||||||||||||||||||||
| Kevlon Foods, Inc. | $400,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $394,857.00 | Grant | Trans-NIH Recovery Act Research Support Varicella zoster virus (VZV) is the causative agent of chicken pox and shingles. The overall objective of this proposal is to understand the nature of physical and functional interactions between the complex VZV major transactivator, IE62, and specific componennts of the cellular transcription apparatus. Such information is critical to our understanding of the complex pathogenesis of VZV infection. It is particularly important in terms of the live attenuated VZV vaccine. Vaccination is now recommended for all children and recently the FDA approved the vaccine for use in the elderly for the prevention of zoster based on an extensive clinical trial. Currently little is known concerning attenuation of the vaccine virus. Since the IE62 gene accumulates the majority of mutations in the attenuated vaccine strains, understanding its interaction with host functions could lead to the development of second generation vaccine whose molecular mechanism of attenuation is well understood. The work proposed involves three Specific Aims. Specific Aim 1: Functional Interaction of IE62 with Cellular Factors. We will examine the functional interaction between the IE62 protein and two essential cellular transcription factors the Mediator complex and HCF-1. This will be done by mapping and mutation of interacting domains and expression of these mutations in the context of the viral genome. Specific Aim 2: Role of DNA Binding in the Mechanism of IE62 Activation. We will determine the specificity and affinity of the IE62- DNA Interaction and the effect of mutations in the DNA-binding domain on IE62 DNA-binding and transactivation and viral gene expression. Specific Aim 3: Interrelationship Between IE62 Structure and Function. We will mutate the IE62 SEAC domains and assess there function in in vitro transcription assays. The growth properties of virus carrying mutations in these domains will be determined. We will determine if the two transcriptional activation domains present in the IE62 homodimer are both required for IE62 function and what functions they perform. These studies will help us to understand the ways in which this important viral protein influences the functions of cells following infection. Since the live attenuated VZV vaccine will be used to prevent chicken pox and shingles throughout the U.S. population it is important to understand how the virus interacts with its human host. This work should also result in information that could be used in strategies to develop better anti-viral drugs and vaccines.... Show more | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 | ||||||||||||||||||||||||
| TRANSPORTATION, NEW YORK DEPARTMENT OF | $392,639.00 | Grant |
Highway Planning and Construction Highway Infrastructure Investment Grant: Available for Use in Any Area (flexible)
This spending item is part of a $2,388,000.00 allocation. See details |
Transportation Department / Federal Highway Administration | 6/15/2009 | ||||||||||||||||||||||||
| J.G.D. Enterprises, LLC | $390,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $389,985.00 | Grant | Trans-NIH Recovery Act Research Support Major developments in molecular biology, coupled with strides in genomics and proteomics, have led to an explosive growth in biological data. To obtain usable, relevant information from these vast databases (e.g. through data mining) it is mandatory to use advaanced computational methods and hardware. The rapidly expanding field of bioinformatics, where biology, computer science, and information technology merge to form a single discipline, has the potential to serve as a bridge between medical informatics and experimental science. In this proposal we focus on a unique cohort of HIV-1 infected subjects, long term non-progressors (LTNP), who can remain asymptomatic for >15 yr without antiretroviral therapy. Many factors underlie the LTNP state. This project, which expands our current bioinformatics studies in a more translational direction, will develop a complex clinical and experimental database that will be analyzed by powerful informatics tools to identify key genes and proteins that contribute to the LTNP phenotype. We hypothesize that using innovative informatics technology that we specifically develop, we shall prepare a publicly available, large, interactive database containing medical, genomic and proteomic information on HIV-1 infected patients that can be queried to guide rational, evidence-based, decision making at both the clinical and public health levels. Our proposal represents a productive partnership between 3 specialized research groups, with extensive expertise in: a) clinical management of HIV-1 disease, b) molecular and cellular immunovirology, and c) bioinformatics and computational sciences. The goal of this biomedical informatics proposal is the characterization and efficient utilization of data obtained from basic biomedical research and integrate it with clinical outcome. The following specific aims are proposed. Specific Aim 1: To identify functional genes and proteins that are unique to our specific HIV-1 infected patient cohorts using state of the art genomic and proteomic technologies. Specific Aim 2: To evaluate the role of human allelic variants in influencing the rate of HIV-1 disease progression using SNP analysis and real time, quantitative PCR. Specific Aim 3: To develop new computational tools to analyze and integrate genomic, proteomic, and clinical data from our HIV-1 patient cohorts and convert them into clinically useful information relating to the pathogenesis, transmission and therapeutic response of HIV-1 infected patients. This will involve the design of: data mining-oriented schemas; advanced algorithms for integrating genomic, proteomic, and clinical data in a data warehouse; and metrics and methods to explore the association between host genetic variations and HIV disease. Ultimately this database will be provided on the web as a publicly accessible resource. This study will contribute to our fundamental understanding of the pathogenesis of HIV infections and identify new biomarkers of disease progression and potential molecular targets for therapy.... Show more | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $389,357.00 | Grant | Trans-NIH Recovery Act Research Support We appreciate the opportunity to refocus this application to achieve a single important aim related to our understanding of young adults' use of male liquor (ML), other alcoholic beverages, and marijuana (MJ), all of which confer high risks for experiencing neggative consequences, including addiction. As we have noted, reviews of this grant application, have noted numerous strength, which are summarized below. a) Malt liquor use is an understudied topic and the use of ML, other alcoholic beverages, and MJ are important public health issues. 2) The proposed research is highly innovative and long overdue. 3) The proposed research is based on a well-articulated conceptual framework and uses careful (i.e., methodologically rigorous) study design. 4) The application is well-written and in response to previous reviews includes assessment of the use of all alcoholic beverages, not just ML. 5) This research team has previous been successful in recruiting a large (> 600) sample of regular ML drinkers. 6) The research environment is excellent and the research team is very productive and led by a PI who is a leader in the alcohol and drug field. Given the previous reviewers' approval of the conceptual model, design, and measures proposed in this application, in this document begin by highlighting the following the following: 1) Selection of one specific aim that can be achieved within the 2 years of available funding and a brief overview of how that aim is reflected in the research design and methods; 2) Submission of a detailed budget similar in total costs to 2 years of the budget submitted as part of the earlier application; 3) Description of the ways in which funding this research stimulates the economy of the Buffalo metropolitan region and the nation; and 4) A description of timelines and milestones to be achieved during the 2-year period. The document ends with a detailed description of the significance of the proposed research.... Show more | Health and Human Services, Department of / National Institutes of Health | 5/07/2009 | ||||||||||||||||||||||||
| HEALTH RESEARCH, INC. | $386,285.00 | Grant | Trans-NIH Recovery Act Research Support Vitamin D has been investigated as a potential preventive therapy for prostate cancer (CaP) because of its many anti-cancer activities. We demonstrate in the transgenic adenocarcinoma of mouse prostate (TRAMP) model of CaP that early treatment with 1,25(OH)2D33 prevents hormone responsive CaP and is associated with decreased proliferation and increased differentiation. The in vivo response of TRAMP prostate to 1,25(OH)2D3 treatment indicates a decrease in cell cycle modulators that regulate G2/M transition and an increase in E-Cadherin, a marker of differentiation. 1,25(OH)2D3 had no preventative effect on castration recurrent CaP. We have identified a novel interaction of VDR with LSD1 and CoREST. LSD1 and CoREST are part of a recently described corepressor complex. LSD1 is a demethylase whose activity s associated with repression of gene transcription and increases in prostate cancer progression. Tranylcypromine (TCP) is a potent LSD1 inhibitor that can increase vitamin D mediated gene transcription. We propose a model in which LSD1 increases during prostate cancer progression and in castration recurrent disease, leading to interaction of VDR with LSD1 which represses VDR mediated gene transcription. The biological consequence of these changes is a loss of vitamin D-í-Şs anti-cancer activity. Therefore, the effectiveness of 1,25(OH)2D3 can be enhanced by combination with LSD1 inhibitors. In this proposal, in Aim I we determine the molecular mediators of 1,25(OH)2D3 chemopreventive activity in vivo. In Aims II and III we test LSD1 as corepressor of vitamin D-í-Şs action and test combination therapy of 1,25(OH)2D3 and a LSD1 inhibitor. Aim I. Determine the in vivo mechanism by which the chemopreventive action of 1,25(OH)2D3 decreases proliferation and increases differentiation in CaP. TRAMP animals are treated with 1,25(OH)2D3 starting at 4 weeks of age and expression of target molecules are examined by western analysis at multiple times during CaP progression. Cell cycle regulators being examined include: cyclin A, cyclin B1, cyclin E, skp2, cdk2, p27, p21, CDKN3, aurora-A, aurora-B, and Bub1. Modulators of differentiation being examined include: E-cadherin, ?+Ć-catenin, Snail and LSD1. Aim II: Test the corepressor complex containing LSD1/CoREST as the molecular mechanism of deregulated VDR-mediated transcription in CaP cells that escape 1,25(OH)2D3-í-Şs chemopreventive activity. The consequence of altering LSD1 activity by shRNA or chemical inhibition and by overexpression on VDR activity will be evaluated. Effect on vitamin D induced growth inhibition is measured by cell counts and MTT assay. Effects on gene expression is measured by qRT-PCR and luciferase reporter assays. Interactions of VDR with LSD1 and CoREST are evaluated by ChIP and Re-ChIP. Aim III: Determine if combination therapy of calcitriol and the LSD1 inhibitor, tranylcypromine (TCP), improves the chemopreventive effectiveness of vitamin D in hormone responsive and castration resistant CaP in an autochthonous model of CaP (TRAMP). TRAMP animals will be treated with 1,25(OH)2D3 alone, TCP alone and 1,25(OH)2D3 in combination with TCP. The impact on hormone responsive, castration recurrent disease and time to palpable tumor will be evaluated. The studies in the proposal will identify the mechanism of vitamin D-í-Şs chemopreventive activity in vivo, establish LSD1 as a corepressor for the vitamin D receptor, and test combination therapy of 1,25(OH)2D3 with LSD1 inhibitors to improve the effectiveness of vitamin D-í-Şs chemopreventive activity. Thus, these studies are fully translational. The rationale for these studies is that an understanding of the mechanism of action of vitamin D chemopreventive activity at the molecular level provides the basis for developing improved therapeutics and identifying patients most/least likely to benefit from vitamin D therapy.... Show more | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $385,377.00 | Grant | Trans-NIH Recovery Act Research Support This application proposes to develop two novel prophylactic and therapeutic non-viral gene transfer strategies that target pulmonary cells in vivo employing nanotechnology. The lung is especially well suited for these treatment strategies as direct contact withh the environment provides a portal for inhalation administration of cDNA and siRNA conjugated nanoplexes. The emergence of drug-resistant strains of human influenza A and B viruses, as well as avian H5N1 influenza viruses with pandemic potential to one or both classes of approved antiviral agents underscores the importance of developing novel antiviral strategies. The primary objective of the R21 phase is to construct an electrostatic complex between a cationic nanoparticle (i.e., Gold Nanorods, GNR) and anionic genetic material (i.e., cDNA or siRNA). These nanoplexes will be engineered such that they can be taken-up and express bioactivity in large airway (i.e., bronchial) epithelial cells with little or no untoward cellular or pulmonary responses. The siRNA/cDNA constructs, which have just recently been synthesized, have dual actions of suppressing the translation of the influenza virulence factor, NS1, as well as independently stimulating type I interferon production through activation of the RIG-I pathway. Stimulation of this antiviral innate immune pathway occurs as a result of a triphosphate (PPP) moiety attached to the 5' end of the siRNA. We will preferentially administer the GNR-5'PPP-NS1siRNA or its counterpart cDNA nanoplexes to the tracheal and bronchial epithelium in vivo, thereby increasing the safety of the treatment. Extension of these nanotechnological approaches can also be applied to treat other infectious, as well as non-infectious acute lung injuries. The focus in the R33 phase will be to demonstrate the therapeutic efficacy of using 5'PPP-NS1siRNA and cDNA-nanoplex targeting of large airway epithelial cells in vivo before and during influenza. In addition to assessing the clearance of influenza virus from the respiratory tract, the R33 phase will specifically examine the ability of 5'PPP-NS1siRNA or cDNA-nanoplexes to stimulate innate antiviral immunity, resulting in alteration of the inflammatory cytokine milieu, adaptive immune response, and antibacterial host defense, as well as prevent or reduce the degree of viral induced respiratory injury and impairment of bacterial clearance. We predict that these large airway epithelial-targeted nanoplexes will lead to prophylactic and therapeutic options that can prevent or significantly reduce the morbidity and severity of symptoms of influenza including the highly pathogenic H5N1 'bird flu' and the risk of secondary bacterial pneumonia, which is the major cause of death secondary to influenza. It is our goal to have a nanoparticle mediated novel antiviral prophylactic and therapeutic strategy at the completion of the R33 phase available for Investigational New Drug filing with the FDA to go for Phase 1 clinical trials as a result of the experiments proposed in this application.... Show more | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 | ||||||||||||||||||||||||
| WSSN LLC | $385,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| HEALTH RESEARCH, INC. | $383,842.00 | Grant | Trans-NIH Recovery Act Research Support Mutation of the retinoblastoma tumor suppressor gene (Rb1) causes the pediatric cancer retinoblastoma and contributes to most types of human cancer. Despite its central role in tumorigenesis, therapies designed to target this pathway have been slow to develop. A detailed understanding of the molecular mechanisms underlying Rb1 mediated tumor suppression will facilitate the development of such therapies. The long-term goal of this continuing project is to identify and characterize these molecular mechanisms. Rb1 protein (pRb) is a negative regulator of the cell cycle, and this cell cycle regulatory activity contributes to tumor suppression. Multiple mechanisms likely contribute to pRb mediated cell cycle control, including the well characterized mechanism involving binding of pRb to E2F transcription factors resulting in transcriptional repression of genes required for cell cycle progression. Another possible mechanism involves targeted degradation of Skp2 by pRb and consequent stabilization of p27Kip1. The ability of pRb to regulate E2F transcription factors is genetically separable from its ability to degrade Skp2. We hypothesize that pRb mediated degradation of Skp2 and stabilization of p27Kip1 contributes to prostate tumor suppression in vivo. Our working model is that post translational stabilization of p27Kip1 (p27) normally enforces a senescence like response to oncogenic stress, thereby curtailing tumor initiation and progression. In the absence of pRb, this tumor suppressive response is muted. The goal of this application is to test the hypothesis using in vitro and in vivo experimental model systems. We have created a mouse strain containing a mutant Rb1 allele (R654W) whose encoded protein is deficient for E2F binding and regulation, but may be competent to target Skp2 for degradation. We propose to use this mutant allele to assess the relative contribution of the pRb/E2F and pRb/p27 mechanisms to prostate tumor suppression in vivo. Two specific aims are proposed: 1) Test whether R654W pRb can suppress prostate tumorigenesis in the mouse; 2) Characterize the contribution of the pRb/Skp2/p27 mechanism to R654W pRb tumor suppressor activity. Successful completion of these specific aims will identify a new mechanism contributing to Rb1 tumor suppression and suggest new therapeutic strategies to treat prostate cancer.... Show more | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $382,903.00 | Grant |
Trans-NIH Recovery Act Research Support Infections caused by Staphylococcus aureus span a wide clinical spectrum, ranging from asymptomatic nasal carriage to endocarditis, bone and joint infections and lethal shock. Increasing rates of S. aureus infection and the emergence of community-acquired straiins drive the need for an increased understanding of the virulence determinants of this emerging pathogen and evaluating the role they play in outcome of patients with S. aureus bacteremia. Evaluating the role of these virulence determinants in humans was limited by the absence of a large, well-characterized collection of bloodstream S. aureus isolates. Such a clinical resource was developed by Vance Fowler (Co-Investigator), when he created one of the world.... Show more
This spending item is part of a $558,617.00 allocation. See details |
Health and Human Services, Department of / National Institutes of Health | 9/24/2009 | ||||||||||||||||||||||||
| Elias Kotzambasis (or an entity to be form | $382,500.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| HYDROGEOLOGIC, INC. | $381,116.01 | Contract | The procurement was for records management, including the organization, identifying project file deficiencies, indexing, digitization, and assembling and making accessible a permanent record file and associated administrative record files (ARF) for the Niagara Falls Storage Site project in Lewiston,, New York.... Show more | U.S. Army Corps of Engineers / U.S. Army Corps of Engineers - civil program financing only | 11/30/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $380,818.00 | Grant | Trans-NIH Recovery Act Research Support The long term goal of this project is to elucidate the roles protein arginine methylation in Trypanosoma brucei gene expression, particularly at the RNA level. These studies will greatly increase our understanding of gene regulation in a medically and economicaally important parasite. In addition, because the effects of arginine methylation on RNA metabolism are not well understood in general, they will also provide insight into a common posttranslational modification in higher eukaryotes.... Show more | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 | ||||||||||||||||||||||||
| CHARTER SCHOOL FOR APPLIED TECHNOLOGIES | $377,670.00 | Grant |
Title I Grants to Local Educational Agencies, Recovery Act Improve teaching and learning for students most at risk of failing to meet State academic achievement standards
This spending item is part of a $907,152,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 4/01/2009 | ||||||||||||||||||||||||
| La Tolteca | $375,000.00 | Loan | 504 Certified Development Loans TO ASSIST SMALL BUSINESS CONCERNS BY PROVIDING LONG TERM FINANCING THROUGH THE SALE OF DEBENTURES TO THE PRIVATE SECTOR | Small Business Administration | |||||||||||||||||||||||||
| CIR ELECTRICAL CONSTRUCTION CORP | $371,700.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| GRAND ISLAND CENTRAL SCHOOL DISTRICT | $369,403.00 | Grant |
Special Education Grants to States, Recovery Act Assist States in providing special education and related services to children with disabilities in accordance with Part B of the IDEA
This spending item is part of a $759,193,000.00 allocation. See details |
Education Department / Office of Special Education and Rehabilitative Services | 4/01/2009 | ||||||||||||||||||||||||
| Akron Animal Hospital P.C. | $360,000.00 | Loan | 504 Certified Development Loans TO ASSIST SMALL BUSINESS CONCERNS BY PROVIDING LONG TERM FINANCING THROUGH THE SALE OF DEBENTURES TO THE PRIVATE SECTOR | Small Business Administration | |||||||||||||||||||||||||
| LACKAWANNA CITY SCHOOL DISTRICT | $359,742.00 | Grant |
Special Education Grants to States, Recovery Act Assist States in providing special education and related services to children with disabilities in accordance with Part B of the IDEA
This spending item is part of a $759,193,000.00 allocation. See details |
Education Department / Office of Special Education and Rehabilitative Services | 4/01/2009 | ||||||||||||||||||||||||
| HEALTH RESEARCH, INC. | $356,346.00 | Grant | Trans-NIH Recovery Act Research Support The aim of this funded R21 proposal is to study the role of dietary supplement selenium (Methylselenocysteine or MSC) in supranutritional doses in retarding cancer growth and synergistically enhancing chemotherapeutic efficacy in combination setting through itss? antiangiogenic activity. This antiangiogenic effect lead to tumor blood vessel normalization that enabled delivery of higher drug within the tumor at a given systemic drug dose administered. This effect was hypothesized to be through down regulation of reactive oxygen species leading to HIF-1á degradation. The proposal uses six different human cancer xenografts from three cancer disease sites ? Head and Neck, Colorectal and Lung. The specific aims of the proposal are as under: Specific Aim 1: Evaluate the effect of Se on antioxidant and vascular (antiangiogenic and normalization) status in tumor xenografts growing sub cutaneously (s.c) in nude mice. Specific Aim 2: Evaluate the effect of Se on tumor vascular volume and permeability using noninvasive dynamic contrast enhanced magnetic resonance imaging (DCE-MRI). Specific Aim 3: Evaluate the effect of Se in vitro on ROS, antioxidants, HIF-1á degradation and on downstream angiogenic markers VEGF, PDGF-B, and MMP-14.... Show more | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 | ||||||||||||||||||||||||
| G. Pacillo Co. Inc. | $355,000.00 | Loan | 504 Certified Development Loans TO ASSIST SMALL BUSINESS CONCERNS BY PROVIDING LONG TERM FINANCING THROUGH THE SALE OF DEBENTURES TO THE PRIVATE SECTOR | Small Business Administration | |||||||||||||||||||||||||
| Q.T.A. Machining Inc. | $355,000.00 | Loan | 504 Certified Development Loans TO ASSIST SMALL BUSINESS CONCERNS BY PROVIDING LONG TERM FINANCING THROUGH THE SALE OF DEBENTURES TO THE PRIVATE SECTOR | Small Business Administration | |||||||||||||||||||||||||
| NORTH COLLINS CENTRAL SCHOOL DISTRICT | $353,569.00 | Grant |
State Fiscal Stabilization Fund (SFSF) - Education State Grants, Recovery Act For the support of public elementary, secondary, and post secondary education and, as, applicable early childhood education programs and services
This spending item is part of a $1,653,930,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 5/08/2009 | ||||||||||||||||||||||||
| STATE UNIVERSITY OF NEW YORK | $352,813.00 | Grant | Federal Work-Study Program Federal Work Study provides need based financial aid to students. | Education Department | 7/01/2009 | ||||||||||||||||||||||||
| Superior Heat Company LLC | $350,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| Solmac, Inc. | $350,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| INSTALLS INC, LLC | $350,000.00 | Contract | Basic In-home Digital converter box installation in IN, KY, MI, OH and WV. Installed 4,230 boxes. | Federal Communications Commission | 5/02/2009 | ||||||||||||||||||||||||
| Atlas Painting and Sheeting Corp | $350,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| MARILLA, TOWN OF | $348,730.00 | Grant | Water and Waste Disposal Systems for Rural Communities - ARRA TOA Code 544, Water only combo loan/grant - Rural Development funds will be used to install 15,000 feet of PVC pipe with one large and three small creek crossings to improve water for residents in the area who are experiencing insufficientt quantity and poor water quality. The project will benefit 148 users.... Show more | Agriculture Department / Rural Utilities Service | 9/04/2009 | ||||||||||||||||||||||||
| EVANS BRANT CENTRAL SCH DIST | $346,745.00 | Grant |
Special Education Grants to States, Recovery Act Assist States in providing special education and related services to children with disabilities in accordance with Part B of the IDEA
This spending item is part of a $759,193,000.00 allocation. See details |
Education Department / Office of Special Education and Rehabilitative Services | 4/01/2009 | ||||||||||||||||||||||||
| HEALTH RESEARCH, INC. | $335,208.00 | Grant | Trans-NIH Recovery Act Research Support Summary description of the project that matches the Award: Our data indicate that the human prostate-derived Ets transcription factor (PDEF) plays an essential role in tumor suppression via downregulation of the expression of antiapoptotic protein survivin. Ecttopic expression of PDEF in PDEF-negative breast cancer cells inhibits survivin expression as well as its promoter activity. In contrast, knockdown of PDEF in PDEF-positive breast cancer cells upregulates survivin expression along with increased cell proliferation in vitro, and increases xenograft tumor take rate and tumor growth in vivo. Importantly, patients with survivin-/PDEF+ tumor show better survival and less relapse than patients with survivin+/PDEF- tumor. Abnormal inhibition of apoptosis is known to be one of the critical steps for oncogenesis and malignant progression. Although the underlying mechanisms are not fully understood, evidence indicates that survivin plays an important role in the initiation, progression, metastasis and recurrence of cancer. Accordingly, many natural dietary components, including resveratrol, silibinin, sulindac, retinoid, selenium and vitamin D compounds that have cancer-preventive and therapeutic effects, downregulate survivin expression. PDEF appears to have an opposing role to survivin and likely via downregulation of survivin expression. It has been shown that PDEF inhibits cancer cell migration, invasion and growth. Based on these observations, we hypothesize that application of survivin and PDEF as interconnected biomarkers and targets to stratify patents with survivin+/PDEF- tumor and patients with survivin-/PDEF+ tumor may facilitate prostate cancer prognosis and personalized medicine. Two specific aims are proposed to test this hypothesis. In Aim 1, we will use a large cohort of prostate cancer tissues to determine survivin and PDEF expression status. Then we will analyze the association of survivin and PDEF expression status with patient survival, cancer metastasis and tumor relapse by appropriate statistical methods. In Aim 2, we will determine the methylation status in the PDEF gene in prostate cancer tissues. Then we will analyze the association of PDEF methylation status with the expression of PDEF and survivin. These studies may provide novel approaches for cancer prognosis and personalized medicine, by stratifying patients with survivin+/PDEF- tumor and patients with survivin-/PDEF+ tumor.... Show more | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 | ||||||||||||||||||||||||
| Deuce Construction Corporation | $330,000.00 | Contract |
Provide all labor, materials , tools and equipment necessary for our project at the VA Western New York Healthcare System, Buffalo NY.
This spending item is part of a $3,186,390.00 allocation. See details |
Department of Veterans Affairs | 5/13/2009 | ||||||||||||||||||||||||
| Deuce Construction Corporation | $330,000.00 | Contract |
furnish all labor, materials, equipment, etc. necessary for our project called RENOVATE WARD 9A at the VA Medical Center
This spending item is part of a $3,186,390.00 allocation. See details |
Department of Veterans Affairs | 5/13/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $327,426.00 | Grant |
Trans-NIH Recovery Act Research Support It is estimated that up to 50,000 children are newly diagnosed annually in the United States with vesicoureteral reflux (VUR) after a urinary tract infection. It is known that in some of these children, VUR is associated with recurrent infection, pyelonephritiss and subsequent renal scarring. This can lead to hypertension and renal insufficiency later on in childhood or in adult life. There remains great confusion, however, regarding the optimal treatment of these children or indeed, if they all require treatment. While it appears that children with the higher grades of dilating reflux (grades IV & V) are at the greatest risk for clinical sequelae, they are a minority of patients. 90% of children have grades I, II or III reflux. The majority of children with low grade reflux will outgrow their reflux before adolescence. Surgical correction of reflux in these children is less commonly required, therefore. Rates of renal scarring and recurrent urinary tract infection are also lower in these children. While long term antibiotic prophylaxis works well in preventing urinary infection, it has been proposed that it may not be necessary in this group, since rates of scarring and recurrent infection are low with low grade reflux. Recently, a new minimally invasive treatment of reflux has been developed and a material known as 'Deflux' has been approved by the FDA for this purpose. This material is injected via a cystoscope around the ureteral orifice. The change in configuration of the orifice caused by this bulking agent cures the reflux. Because of its ease of use and low morbidity of application, it has been proposed that this be employed as initial therapy in the majority of children with low grade reflux. Successful treatment with Deflux might render the need for long term surveillance, either on or off antibiotics unnecessary. The optimal treatment for the majority of the thousands of children with reflux, therefore, remains unknown. Do they simply require daily antibiotics? Can they be safely observed without prophylaxis? Do they require an ambulatory cystoscopic procedure? A prospective randomized study is proposed to answer this question in girls, aged one to five years with grades II or III reflux, diagnosed after a urinary tract infection. The three major treatment groups would be antibiotic prophylaxis, observation without prophylaxis, or endoscopic therapy with Deflux (ET). The clinical endpoints measured would be recurrent febrile or non-febrile urinary infections and renal scarrin... Show more
This spending item is part of a $366,736.00 allocation. See details |
Health and Human Services, Department of / National Institutes of Health | 8/21/2009 | ||||||||||||||||||||||||
| HEALTH RESEARCH, INC. | $321,845.00 | Grant | Trans-NIH Recovery Act Research Support The anti hormonal drug tamoxifen is approved for the treatment of women with early and advanced and early stage estrogen receptor (ER)-positive breast cancer. Tamoxifen is known to exert its effects on breast cancer cells by binding to the estrogen receptor, thhereby preventing the binding of estrogen. However, a major clinical problem is that a large number of patients with ER-positive breast tumors either do not respond to tamoxifen therapy or develop resistance to it. Although several plausible reasons for such resistance have been suggested, the mechanisms of resistance to tamoxifen therapy remain largely unclear. The award is to test the hypothesis that relieving suppression of tumor suppressor p53 by estrogen receptor ?+ć (ER?+ć) could be an important mechanism underlying tamoxifen action in breast cancer patients. The benefit of tamoxifen-í-Şs effect becomes irrelevant if the tumor has mutant (and therefore dysfunctional) p53, and therefore, p53 status and tamoxifen-í-Şs ability to activate p53 function could be important factors in resistance to tamoxifen therapy. To test these hypotheses, a pilot randomized clinical trial of 50 pre-menopausal women with newly diagnosed ER-positive breast cancer expressing wild type p53 is proposed. The award will support this clinical trial. The Specific Aims are: (1) Investigate the status of ER-p53 interaction in patients treated with 20 mg of tamoxifen for four weeks prior to surgery as compared to the interaction in untreated patients, and (2) Confirm the wild type status of p53 and analyze the functional status of p53 pathway by monitoring expression of selected p53-target genes in tumors in patients who have or have not been treated with 20 mg tamoxifen for four weeks prior to surgery. These studies will be conducted prospectively in newly diagnosed breast cancer patients (to be recruited to the Roswell park Cancer Institute over next two years) using a combination of clinical, pathological, cellular, and molecular biology expertise. The status of ER and p53, their interaction, and its consequences in breast tumors will be analyzed with immunohistochemical, cellular, and molecular approaches. This project brings in a paradigm shift to the way resistance to tamoxifen therapy had been addressed to-date. Results from the proposed studies should help to devise new methods to screen patients for tamoxifen therapy and also lead to the development of better diagnostic and intervention strategies. Our studies by providing clues to screen patients who would be benefited by tamoxifen therapy, will help to avoid unnecessary exposure of patients with tumors unresponsive to this drug with several unpleasant side effects. Therefore, our study should constitute an important step toward personalized breast cancer therapy aimed at maximum therapeutic benefit to the patient.... Show more | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 | ||||||||||||||||||||||||
| Cheektowaga Central School District | $317,974.00 | Grant |
Special Education Grants to States, Recovery Act Assist States in providing special education and related services to children with disabilities in accordance with Part B of the IDEA
This spending item is part of a $759,193,000.00 allocation. See details |
Education Department / Office of Special Education and Rehabilitative Services | 4/01/2009 | ||||||||||||||||||||||||
| TONAWANDA, TOWN OF | $316,781.00 | Grant |
Community Development Block Grant ARRA Entitlement Grants (CDBG-R)(Recovery Act Funded) The Community Development Block Grant Program enables local governments to undertake a wide range of activities intended to create suitable living environments, provide decent affordable housing and create economiic opportunities, primarily for persons of low and moderate income. Under the Recovery Act, the Town of Tonawanda has given priority to projects that can award contracts based on bids within 120 days of the grant agreement. Three of the five projects that the Town originally planned on for CDBG-R have been substantially completed. The other two projects will be completed within the next 2 quarters.... Show more
This spending item is part of a $505,121.00 allocation. See details |
Housing and Urban Development Department | 8/13/2009 | ||||||||||||||||||||||||
| KENMORE MUNCIPAL HOUSING AUTHORITY | $308,762.00 | Grant | Public Housing Capital Fund Stimulus (Formula) Recovery Act Funded EMERGENCY GENERATOR REPLACEMENT, HALLWAY FLOORING REPLACEMENT, PARKING LOT RE-SURFACE, LIGHTING REPLACEMENT, BATHROOM VANITY REPLACEMENT | Housing and Urban Development Department | 3/18/2009 | ||||||||||||||||||||||||
| ECOLOGY AND ENVIRONMENT, INC. | $306,572.00 | Contract |
E & E will (1) develop an Engineering and Design Quality Control Plan; (2) provide A-E support for continuation of the Buffalo River Environmental Dredging Feasibility Study; (3) provide visualization and volume quantification of Dredged Sediments within the Buffalo River Project Area; (4) provide AA-E Support of the USACE Regional Sediment Management (RSM) Authority (SEC 204) on the Buffalo River, New York; (5) provide A-E Support to the Great Lakes Fishery and Ecosystem Restoration (GLFER) Authority and develop a preliminary restoration plan; and (6) provide integrated Lower Maumee River -- Western Lake Erie Basin Modeling Support.... Show more
This spending item is part of a $486,496.00 allocation. See details |
Office of the Secretary of Defense | 6/24/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $304,179.00 | Grant | Trans-NSF Recovery Act Reasearch Support A recently developed technology, called opportunistic coding, can greatly improve the effciency of wireless networks. However, the problems of cooperation and security in opportunistic-coding-based (OCB) wireless networks have not received suffcient attention.. Here cooperation problems are the problems introduced by the existence of selfish nodes in the wireless networks, while security problems are the problems introduced by the existence of adversarial nodes. This work is to design and implement solutions that can provide cooperation and security guarantees for OCB wireless networks. The research work can be divided into studied of three problem areas, namely the cooperation problems, the security problems, and the interplays of cooperation and security. The work also includes the dissemination of related knowledge to students at various levels. Intellectual Merit: The results of this work will signiffcantly improve OCB wireless networks in terms of cooperation and security. Furthermore, these results will also have broader theoretical interests, because a part of the techniques to be developed will be applicable to economic incentives problems in other settings as well. Broader Impacts: First, the developed technical solutions will benefit the society because they make it possible to widely deploy OCB wireless networks to environments with selfish or adversarial nodes. Second, the educational component of this work will build capacity in cooperation and security at various levels.... Show more | National Science Foundation | 8/14/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $304,179.00 | Grant | Trans-NSF Recovery Act Reasearch Support A recently developed technology, called opportunistic coding, can greatly improve the effciency of wireless networks. However, the problems of cooperation and security in opportunistic-coding-based (OCB) wireless networks have not received suffcient attention.. Here cooperation problems are the problems introduced by the existence of selfish nodes in the wireless networks, while security problems are the problems introduced by the existence of adversarial nodes. This work is to design and implement solutions that can provide cooperation and security guarantees for OCB wireless networks. The research work can be divided into studied of three problem areas, namely the cooperation problems, the security problems, and the interplays of cooperation and security. The work also includes the dissemination of related knowledge to students at various levels. Intellectual Merit: The results of this work will signiffcantly improve OCB wireless networks in terms of cooperation and security. Furthermore, these results will also have broader theoretical interests, because a part of the techniques to be developed will be applicable to economic incentives problems in other settings as well. Broader Impacts: First, the developed technical solutions will benefit the society because they make it possible to widely deploy OCB wireless networks to environments with selfish or adversarial nodes. Second, the educational component of this work will build capacity in cooperation and security at various levels.... Show more | National Science Foundation | 8/14/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $300,000.00 | Grant | Trans-NSF Recovery Act Reasearch Support This research project investigates climatic change from a global perspective through archaeological excavation and survey in the Puuc region of Yucatan, Mexico and at the Maya center of Xcoch. Climate change in the Arctic is not just a contemporary phenomenon,, such change had social and cultural consequences for many past human societies far from northern Polar Regions, including the Maya lowlands. Changing climate facilitated Norse colonization of the North Atlantic Islands during the Medieval Warm Period (AD 800-1300). At about the same time, the Maya of Yucatan, Mexico, were experiencing disruptions to rainfall patterns leading to sustained periods of drought. How Arctic climate change affected processes of cultural development and decline in the North Atlantic and Maya Lowlands has the potential to inform us today regarding the far reaching and serious cultural-environmental impact of global climate change. Climate data from places like the Puuc region, characterized as a semi-arid tropical climate and dry forest vegetation that suffers from a long precarious dry season, has the potential to inform us about the complex effects that Arctic climate change had and has on the global climate system. Climate change has long been seen as a major factor in the decline of ancient Maya civilization. Cycles of drought affecting agriculture and available drinking water in particular are believed to have being critical in the phenomenon known as the Classic Maya collapse beginning around the 9th century AD. The site of Xcoch is uniquely suited for climatic change research because it had a long occupation but experienced significant depopulations by the 9th century, contains a deep cave to a permanent water source, and there are many ponding features (aguadas); all these factors give Xcoch the potential to provide long-term paleoclimatic information. The nearby centers of Uxmal, Muluch Tzekel, and Xuch also contain aguadas and there are several other deep caves in the region that will be tested. This work is largely based upon new, untested ideas and has never been tried in the Yucatan but involves new approaches, requires diverse expertise, and engages interdisciplinary perspectives. Survey and excavation at Xcoch will resume in 2009 when multidisciplinary climate change data will be collected, analyzed, and compared with northern data. This research engages the Arctic community because it is becoming increasingly apparent that Arctic climate changes have global culture-environmental impacts. In order to fully understand what those impacts are, interdisciplinary and cross regional investigations, such as the proposed project, need to take place both in the north and in the south engaging the scientific community in a global discussion. The data that the PI expects to uncover at Xcoch will be added to this ongoing discussion with northern scientists. This research is viewed as potentially transformational, connecting what up to this point have been primarily regionalized archaeological research on the affects of climate change on local social and cultural systems, the Xcoch project will attempt globalize this research by connecting the north with the south.... Show more | National Science Foundation | 9/28/2009 | ||||||||||||||||||||||||
| J. D. Cousins, Inc. | $300,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| D. Jones Electric, Inc. d/b/a Tunney Elec | $300,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $299,999.00 | Grant | Trans-NSF Recovery Act Reasearch Support This award is funded under the American recovery and Reinvestment Act of 2009 (Public Law 111-5) The aim of this project is to develop new structural architectures for resisting and mitigating the effects of impulsive loadings, such as blast and high velocity impacts, using functionally graded protective systems. The research approach combines theoretical concepts from wave propagation and nonlinear dynamics with a heuristic optimization methodology, based on genetic algorithms, to develop protective systems that have spatially varying stiffness, density and damping. In particular, this research will investigate functionally graded material systems, along with strategically allocated voids and solid or fluid inclusions for the objective of attenuating stress waves imparted on a structural system by blast and high velocity impacts. The first phase of the research will feature the use of numerical simulations, within a parallel grid computing environment, to develop novel functionally graded protective system concepts. A rigorous experimental investigation will then validate the effectiveness of the proposed functionally graded protective systems for mitigating impulsive loads and provide feedback for further enhancements of these protective systems. The impact of the project will occur at several levels. The research will lead to the generation of new knowledge associated with functionally graded materials and systems, along with the development of robust optimization tools that rely on coupling genetic algorithm methodology with finite element analysis to tailor material architectures for mitigating blast and high velocity impact loading. The validated functionally graded protective systems will enable engineers to apply these new design concepts in structural systems vulnerable to blast and high velocity impact environment. Finally, this has the potential to transform the present design philosophy for structural design under blast and high velocity impacts from one that emphasizes hardening to one focused on energy and momentum management. The project involves the education and mentoring of at least one doctoral student, the research findings will be incorporated into several graduate level courses, including one specifically on blast engineering and a web-based repository will be established to enable broad dissemination of the research results.... Show more | National Science Foundation | 6/02/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $299,999.00 | Grant | Trans-NSF Recovery Act Reasearch Support This award is funded under the American recovery and Reinvestment Act of 2009 (Public Law 111-5) The aim of this project is to develop new structural architectures for resisting and mitigating the effects of impulsive loadings, such as blast and high velocity impacts, using functionally graded protective systems. The research approach combines theoretical concepts from wave propagation and nonlinear dynamics with a heuristic optimization methodology, based on genetic algorithms, to develop protective systems that have spatially varying stiffness, density and damping. In particular, this research will investigate functionally graded material systems, along with strategically allocated voids and solid or fluid inclusions for the objective of attenuating stress waves imparted on a structural system by blast and high velocity impacts. The first phase of the research will feature the use of numerical simulations, within a parallel grid computing environment, to develop novel functionally graded protective system concepts. A rigorous experimental investigation will then validate the effectiveness of the proposed functionally graded protective systems for mitigating impulsive loads and provide feedback for further enhancements of these protective systems. The impact of the project will occur at several levels. The research will lead to the generation of new knowledge associated with functionally graded materials and systems, along with the development of robust optimization tools that rely on coupling genetic algorithm methodology with finite element analysis to tailor material architectures for mitigating blast and high velocity impact loading. The validated functionally graded protective systems will enable engineers to apply these new design concepts in structural systems vulnerable to blast and high velocity impact environment. Finally, this has the potential to transform the present design philosophy for structural design under blast and high velocity impacts from one that emphasizes hardening to one focused on energy and momentum management. The project involves the education and mentoring of at least one doctoral student, the research findings will be incorporated into several graduate level courses, including one specifically on blast engineering and a web-based repository will be established to enable broad dissemination of the research results.... Show more | National Science Foundation | 6/02/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $299,689.00 | Grant | Trans-NSF Recovery Act Reasearch Support The main research objective of this award is the development of a framework for accurate estimation of tumor target dynamics which enables safe and effective Adaptive Conformal Radiation Therapy for cancer treatment. Two specific aims of this research are 1) cconstruction of models correlating body surface motion to the motion of the tumor and 2) development of algorithms for state uncertainty characterization and propagation for timely acquisition of tumor motion data. The research approach progresses from the development of a simple rigid body point mass representation of the tumor, followed by a finite dimensional rigid body model and concluding with a model which accounts for the flexible modes of the tumor dynamics. In close collaboration with our project members from Roswell Park Cancer Institute (RPCI), comprehensive experiments will be performed in a clinical scenario to validate the developed framework. Deliverables include a suite of tumor motion models validated via lab experiments, algorithms for characterizing and propagating state uncertainty in tumor motion models, documentation of research results and undergraduate and graduate student education. If successful, this research has the potential to significantly improve the effectiveness of the conventional radiation therapy. This research will facilitate rational design of even more potent radiation treatment while minimizing: 1) exposure of healthy tissues to toxic radiations, 2) exposure to X-ray imaging doses and most importantly, 3) probability of relapse of tumor. This award facilitates collaboration between researchers in engineering and biomedical sciences. Through this kind of collaboration between two fields, expansion of the fundamental knowledge in both fields is expected. The goals of the broader impact portion of this award will be met in part by incorporating various aspects of the research program into educational activities as well.... Show more | National Science Foundation | 6/29/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $299,688.00 | Grant | Trans-NSF Recovery Act Reasearch Support The main research objective of this award is the development of a framework for accurate estimation of tumor target dynamics which enables safe and effective ?Adaptive Conformal Radiation Therapy? for cancer treatment. Two specific aims of this research are 1)) construction of models correlating body surface motion to the motion of the tumor and 2) development of algorithms for state uncertainty characterization and propagation for timely acquisition of tumor motion data. The research approach progresses from the development of a simple rigid body point mass representation of the tumor, followed by a finite dimensional rigid body model and concluding with a model which accounts for the flexible modes of the tumor dynamics. In close collaboration with our project members from Roswell Park Cancer Institute (RPCI), comprehensive experiments will be performed in a clinical scenario to validate the developed framework. Deliverables include a suite of tumor motion models validated via lab experiments, algorithms for characterizing and propagating state uncertainty in tumor motion models, documentation of research results and undergraduate and graduate student education. If successful, this research has the potential to significantly improve the effectiveness of the conventional radiation therapy. This research will facilitate rational design of even more potent radiation treatment while minimizing: 1) exposure of healthy tissues to toxic radiations, 2) exposure to X-ray imaging doses and most importantly, 3) probability of relapse of tumor. This award facilitates collaboration between researchers in engineering and biomedical sciences. Through this kind of collaboration between two fields, expansion of the fundamental knowledge in both fields is expected. The goals of the broader impact portion of this award will be met in part by incorporating various aspects of the research program into educational activities as well.... Show more | National Science Foundation | 6/29/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $299,000.00 | Grant | Trans-NSF Recovery Act Reasearch Support n/a | National Science Foundation | 9/14/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $299,000.00 | Grant | Trans-NSF Recovery Act Reasearch Support This award supports theoretical research and education focused on electron-phonon kinetics and electric, thermal, and thermomagnetic transport in low-dimensional conductors, nanomaterials, and strongly correlated materials such as doped Mott dielectrics, e.g. novel superconductors and conducting polymers. Vibrating boundaries, defects, or dopants generates another channel of electron-phonon interaction, which interferes with the usual electron-phonon and elastic electron scattering. The interference of scattering mechanisms drastically modifies kinetic and transport phenomena. The interference effects can be strong and easily observable. While effects of interference have been known for some time, the research in this field is limited.-á The PIs will investigate electron-phonon kinetics and electric, thermal, and themomagnetic transport in low-dimensional structures, such as heterostructures, ultrathin films, multi-walled carbon nanotubes, nanowires, metallic clusters, and quantum dot arrays. In low dimensions, strong enhancement of interference effects is expected due to a smaller electron momentum transfer and due to intrinsic peculiarities in the momentum transfer related to the collective excitations. The PIs will investigate electron-phonon interference effects in specific materials, such as graphene and various doped Mott dielectrics. The research is aimed to contribute to the development of critical insights into the quantum interference of scattering mechanisms in kinetics and transport and will contribute to significantly improved theoretical techniques, related to the quantum transport equation and Feynman-Keldysh diagrammatic techniques. This research program contributes to developing effective ways to manage electron-phonon transport and energy transfer which will, in turn, strongly impact the development of advanced nanodevices and materials. A number of puzzling experimental results will find their explanation in the framework developed by this program. The project will have broader impacts through its contributions to education, and by developing theoretical models that can have impact in materials science and engineering. Nanoscale thermal management will substantially affect practically all branches of the electronics industry. This research will have immediate impact on the development of nanodevices in which energy transfer is ?tailored? to specific applications, e.g. ultrasensitive nanocalorimeters and single quanta nanodetectors operating at low and moderate temperatures. With graduate and undergraduate students, the PIs will develop a set of specialized experiments for elementary and high school students. These demonstrations are directly related to modern electronics and nanotechnology. The PIs will incorporate information technologies via Java Applets; they are extending these applets to incorporate the nanoworld energy transfer. They are also developing an interactive exhibit for the Physical World Science Studio of the Buffalo Museum of Science that will help to promote nanotechnology to a broader public. Lectures and demonstrations will be developed at a level appropriate for the general public. NON-TECHNICAL SUMMARY This award supports theoretical research aimed to elucidate the microscopic mechanisms that control how heat and electricity flow through materials structures and devices that are thousands of times smaller than the diameter of a human hair. The PIs will develop a theory on the level of electrons and the atomic-scale surfaces and defects, and vibrations that they encounter as they flow through these tiny structures.-á This project will contribute to the intellectual foundations for managing heat dissipation at small length scales anticipated for future circuit feature sizes of semiconductor devices.-á ?The complete abstract for this award is available in Research.gov at www.research.gov?... Show more | National Science Foundation | 9/14/2009 | ||||||||||||||||||||||||
| ECOLOGY AND ENVIRONMENT, INC. | $298,771.00 | Contract |
DESCRIPTION: FIELD WORK IN SUPPORT OF REMEDIAL INVESTIGATION AND TECHNICAL ASSISTANCE FOR CERCLA PROCESSING AND POTENTIAL FOLLOWUP ACTIVITIES AT SYLVANIA CORNING FUSRAP SITE LOCATED IN HICKSVILLE, NY. EXPECTED OUTCOMES: COMPLETE REMEDIAL INVESTIGATION FIELD WORK... Show more
This spending item is part of a $4,499,960.00 allocation. See details |
U.S. Army Corps of Engineers / U.S. Army Corps of Engineers - civil program financing only | 5/27/2009 | ||||||||||||||||||||||||
| MULTIPLE RECIPIENTS | $298,414.00 | Loan | Very Low to Moderate Income Housing Loans - Guaranteed Single Family Housing Guaranteed Loans - ARRA | Agriculture Department / Rural Housing Service | |||||||||||||||||||||||||
| HEALTH RESEARCH, INC. | $297,488.00 | Grant | Trans-NIH Recovery Act Research Support Asthma is a disease of chronic inflammation marked by periodic bouts of acute exacerbations of airway obstruction, and early sub-clinical eosinophilic pulmonary inflammation precedes the development of asthma in children. Why certain individuals develop asthmaa and factors contributing to the severity of acute exacerbations remain poorly understood. The ST6Gal-1 sialyltransferase constructs the sialyl ?+ć2,6 to Gal?+Ć1,4GlcNAc glycan structures. Our preliminary data point to a previously unrecognized role of ST6Gal-1 in modulating experimental allergic airway inflammation. Mutant mice with ST6Gal-1 deficiencies have exaggerated acute allergic airway inflammation. Expression of recombinant ST6Gal-1 in vivo can attenuate the pulmonary eosinophilia, suggesting a therapeutic potential for ST6Gal-1. Following induction of experimental allergic airway inflammation, wild-type mice with normal ST6Gal-1 expression profiles had significantly depressed circulatory ST6Gal-1 levels. Therefore, natural circulatory ST6Gal-1 levels and serum sialylation products may have potential in identifying persons at risk for allergic airway disease and as a marker for disease severity. This is an exploratory proposal to test the hypothesis that ST6Gal-1 can regulate allergic respiratory inflammation and to evaluate ST6Gal-1 as a marker for asthma disease severity and as a therapeutic target. Specifically, we propose to 1) determine the extent that pulmonary inflammation and asthma-like pathologies are affected in mutant mice with deficiencies in ST6Gal-1; 2) determine the extent that pulmonary inflammation and pathologies can be mitigated by in vivo supplementing of ST6Gal-1; and 3) assess the relationship of circulatory ST6Gal-1 levels in patients with atopic asthma during exacerbations and asymptomatic periods, and normal volunteers. The goal of the proposed research is to generate the foundation data for future efforts that will focus on developing ST6Gal-1 as a potential early predictor and prognostic marker of allergic airway disease and as a therapeutic target for drug development.... Show more | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $296,779.00 | Grant |
Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (03) Biomarker Discovery and Validation, and specific Challenge Topic, 03-DE-101: Development, Refinement, or Validation of Biomarkers Relevant to Oral or Craniofacial Disorders. The goal of this proposed study iss to measure a series of inflammatory biomarkers in saliva and serum to examine to what extent non-invasive salivary biomarkers can be used to characterize those same biomarkers measured in serum. We propose to assess inflammatory biomarkers in saliva and serum samples that are available from previously collected and frozen samples from two funded and completed federally supported studies investigating the association of osteoporosis and periodontal disease (DOD #OS950077; R01DE013505). Samples of saliva and blood were collected, processed and stored using standardized protocols at baseline (DOD study) and again in the same participants prospectively approximately 5 years later (R01). Participants were postmenopausal women recruited into these 2 ancillary studies from the University at Buffalo clinical center of the NIH Women's Health Initiative Observational Study. These stored samples are a unique resource that will be used to measure a panel of inflammatory biomarkers selected for their potential importance in both oral and systemic health. The stored samples were collected at two time points (baseline and 5 years later) at clinic visits. Both saliva and serum blood were collected from these participants on the same day and immediately processed for frozen storage. At these same visits, oral examinations were conducted according to standardized protocols to assess indices of oral and periodontal health (CAL, ACH, bleeding, plaque, calculus, tooth loss, DMFT, oral bone density). Assessments of bone density (DXA), body composition and other physical measures were obtained. Information was collected on participant demographics, personal habits, lifestyle factors, psychosocial factors, dietary intake, physical activity, medication/supplement use, occupation, family history, health practices and medical history. The primary aim of this proposed study is to measure a panel of biomarkers of inflammation in stored saliva samples and determine to what extent salivary levels of these biomarkers are able to characterize these same biomarkers measured in samples of stored serum (N=920). We also propose to determine to what extent the levels of these biomarkers and their relationship to each other change over time (collected at baseline and 5 years later, N=400). In addition, we will determine to what extent baseline markers in salvia and in serum are able to characterize prevalent periodontal disease at baseline, and predict incidence of new and progression of existing periodontal disease (N=920). These data are critically important and significant for several reasons. First, if we are able to characterize serum levels of these biomarkers using saliva, this would provide a novel and non-invasive method of assessing systemic inflammation in older women, which could have many applications. Second, the information collected here will allow us to develop prediction models for incident periodontal disease and also for progression of existing disease. Third, although the focus of this proposed study is to utilize the biomarkers to characterizing periodontal disease, the salivary biomarkers measured in saliva could be used more generally in other chronic diseases thought to be associated with inflammation. For example, in this cohort we would be able to explore salivary biomarkers in the prediction of bone density and osteoporosis which is well characterized in this cohort. We may be able to explore the relation in other chronic diseases that are also assessed as part of routine outcomes collection in WHI. The complete abstract for this award is available at http://report.nih.gov/recovery/?... Show more
This spending item is part of a $479,574.00 allocation. See details |
Health and Human Services, Department of / National Institutes of Health | 9/22/2009 | ||||||||||||||||||||||||
| John Eberz (Real Estate entity to be forme | $295,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| Brian Parisi Copier Systems Inc. | $291,000.00 | Loan | 504 Certified Development Loans TO ASSIST SMALL BUSINESS CONCERNS BY PROVIDING LONG TERM FINANCING THROUGH THE SALE OF DEBENTURES TO THE PRIVATE SECTOR | Small Business Administration | |||||||||||||||||||||||||
| THE CLAREMOUNT | $289,406.00 | Grant | Section 8 Housing Assistance Payments Program Special Allocations (Recover Contract Svs S8 Funds | Housing and Urban Development Department / Federal Housing Commissioner | |||||||||||||||||||||||||
| SURVEY SERVICES INC | $285,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| ERIE 2-CHAUTAUQUA, CATTARAUGUS BOCES | $282,000.00 | Grant |
State Fiscal Stabilization Fund (SFSF) - Government Services, Recovery Act Government Services Fund - for public safety and other government services which may include assistance for elementary and secondary education and public institutions of higher education, and for modernization , renovation or repair of public school facilities and institutions of higher education facilities, including modernization, renovation and repairs that are consistent with a recognized green building rating... Show more
This spending item is part of a $367,990,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 5/08/2009 | ||||||||||||||||||||||||
| Cornerstone Capital Wealth Management In | $280,000.00 | Loan | 504 Certified Development Loans TO ASSIST SMALL BUSINESS CONCERNS BY PROVIDING LONG TERM FINANCING THROUGH THE SALE OF DEBENTURES TO THE PRIVATE SECTOR | Small Business Administration | |||||||||||||||||||||||||
| BUFFALO CITY SCHOOL DISTRICT | $277,763.00 | Grant |
Special Education - Preschool Grants, Recovery Act Assist States to make available special education and related services for children with disabilities age 3 through 5 years, and at a State's discretion, to 2 year old children with disabilities who will reach age three during the school year
This spending item is part of a $35,017,500.00 allocation. See details |
Education Department / Office of Special Education and Rehabilitative Services | 4/01/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $277,375.00 | Grant | Trans-NIH Recovery Act Research Support This project investigates 'impulsivity' as a predisposing factor for drug abuse. Drug abuse researchers have extensively studied 'reward-related' factors that facilitate drug-seeking behaviors, including both unconditioned and conditioned positive affective ressponses to drugs while ignoring 'impulsivity-related' processes that normally inhibit or limit the use of drugs. We believe that processes related to impulsivity may be as important as reward processes in determining whether an individual will use drugs. One reason for the lack of attention to 'impulsivity related' factors may be the lack of adequate laboratory models. The primary objective of the proposed research is to develop and use laboratory-based, behavioral measures of impulsivity to study the relationship between impulsive processes and drug abuse. Our own research as well as other recent findings indicates that 'impulsivity' does not refer to a single process or trait. Instead, several distinct behavioral processes appear to underlie the broad category of 'impulsive behaviors'. One process that can result in impulsive behaviors is the preference for smaller, more immediate rewards over larger delayed rewards, and it is measured using the delay discounting task. A second process corresponds to the inability to inhibit (stop) a prepotent response. This is referred to as behavioral inhibition and is measured using the Stop Task. We have identified a new, third process, which relates to attention. Impairments in attention have not been studied extensively in relation to drug abuse; sustained attention is likely to be important for self-control, particularly during periods of abstinence from drug taking behaviors. The proposed project will use non-human laboratory models of impulsivity to determine the strength of association between cocaine self-administration and impulsivity as measured by delay discounting and sustained attention tasks. A self-administration (SA) procedure which includes acquisition of drug taking, escalation of drug intake, extinction of drug taking, and finally cue-induced reinstatement of drug taking, which models important features of human drug use will be used. We have previously accumulated promising data on these tasks, and the proposed studies will provide important information validating the role of specific types of impulsive behaviors in drug abuse. The proposed studies will provide important new information concerning putative animal models of impulsivity, and the ability of these models to predict cocaine self-administration.... Show more | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $277,375.00 | Grant | Trans-NIH Recovery Act Research Support This project investigates 'impulsivity' as a predisposing factor for drug abuse. Drug abuse researchers have extensively studied 'reward-related' factors that facilitate drug-seeking behaviors, including both unconditioned and conditioned positive affective ressponses to drugs while ignoring 'impulsivity-related' processes that normally inhibit or limit the use of drugs. We believe that processes related to impulsivity may be as important as reward processes in determining whether an individual will use drugs. One reason for the lack of attention to 'impulsivity related' factors may be the lack of adequate laboratory models. The primary objective of the proposed research is to develop and use laboratory-based, behavioral measures of impulsivity to study the relationship between impulsive processes and drug abuse. Our own research as well as other recent findings indicates that 'impulsivity' does not refer to a single process or trait. Instead, several distinct behavioral processes appear to underlie the broad category of 'impulsive behaviors'. One process that can result in impulsive behaviors is the preference for smaller, more immediate rewards over larger delayed rewards, and it is measured using the delay discounting task. A second process corresponds to the inability to inhibit (stop) a prepotent response. This is referred to as behavioral inhibition and is measured using the Stop Task. We have identified a new, third process, which relates to attention. Impairments in attention have not been studied extensively in relation to drug abuse; sustained attention is likely to be important for self-control, particularly during periods of abstinence from drug taking behaviors. The proposed project will use non-human laboratory models of impulsivity to determine the strength of association between cocaine self-administration and impulsivity as measured by delay discounting and sustained attention tasks. A self-administration (SA) procedure which includes acquisition of drug taking, escalation of drug intake, extinction of drug taking, and finally cue-induced reinstatement of drug taking, which models important features of human drug use will be used. We have previously accumulated promising data on these tasks, and the proposed studies will provide important information validating the role of specific types of impulsive behaviors in drug abuse. The proposed studies will provide important new information concerning putative animal models of impulsivity, and the ability of these models to predict cocaine self-administration.... Show more | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 | ||||||||||||||||||||||||
| CIR ELECTRICAL CONSTRUCTION CORP | $275,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| Cheektowaga Central School District | $274,624.00 | Grant |
Title I Grants to Local Educational Agencies, Recovery Act Improve teaching and learning for students most at risk of failing to meet State academic achievement standards
This spending item is part of a $907,152,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 4/01/2009 | ||||||||||||||||||||||||
| CHEEKTOWAGA, TOWN OF | $273,744.00 | Grant | Community Development Block Grant ARRA Entitlement Grants (CDBG-R)(Recovery Act Funded) Installation of drainage system in Cedargrove Heights; replacement of hazardous sidewalks in the Villages of Depew and Sloan. | Housing and Urban Development Department | 6/05/2009 | ||||||||||||||||||||||||
| BENCHMARK CEDAR RIDGE ELDERLY TOWER | $270,875.00 | Grant | Section 8 Housing Assistance Payments Program Special Allocations (Recover Contract Svs S8 Funds | Housing and Urban Development Department / Federal Housing Commissioner | |||||||||||||||||||||||||
| EVANS BRANT CENTRAL SCH DIST | $269,305.00 | Grant |
Title I Grants to Local Educational Agencies, Recovery Act Improve teaching and learning for students most at risk of failing to meet State academic achievement standards
This spending item is part of a $907,152,000.00 allocation. See details |
Education Department / Office of Elementary and Secondary Education | 4/01/2009 | ||||||||||||||||||||||||
| SPRINGVILLE-GRIFFITH INSTITUTE CENTRAL SCHOOL DISTRICT | $267,892.00 | Grant |
Special Education Grants to States, Recovery Act Assist States in providing special education and related services to children with disabilities in accordance with Part B of the IDEA
This spending item is part of a $759,193,000.00 allocation. See details |
Education Department / Office of Special Education and Rehabilitative Services | 4/01/2009 | ||||||||||||||||||||||||
| Zoladz Construction Co., Inc. | $267,200.00 | Contract |
Abatement/Demolition of buildings 6, 7, 11, and 35 at Samual S. Strattion VA in Albany
This spending item is part of a $500,180.00 allocation. See details |
Department of Veterans Affairs | 6/30/2009 | ||||||||||||||||||||||||
| Zoladz Construction Co., Inc. | $267,200.00 | Contract |
Demolition/Abatement of Buildings 6,7,11 and 35
This spending item is part of a $500,180.00 allocation. See details |
Department of Veterans Affairs | 6/30/2009 | ||||||||||||||||||||||||
| Aspire Family Dentistry Buffalo PLLC | $266,000.00 | Loan | 504 Certified Development Loans TO ASSIST SMALL BUSINESS CONCERNS BY PROVIDING LONG TERM FINANCING THROUGH THE SALE OF DEBENTURES TO THE PRIVATE SECTOR | Small Business Administration | |||||||||||||||||||||||||
| East Aurora Union Free School District | $264,902.00 | Grant |
Special Education Grants to States, Recovery Act Assist States in providing special education and related services to children with disabilities in accordance with Part B of the IDEA
This spending item is part of a $759,193,000.00 allocation. See details |
Education Department / Office of Special Education and Rehabilitative Services | 4/01/2009 | ||||||||||||||||||||||||
| DEPEW UNION FREE SCHOOL DISTRICT | $263,926.00 | Grant |
Special Education Grants to States, Recovery Act Assist States in providing special education and related services to children with disabilities in accordance with Part B of the IDEA
This spending item is part of a $759,193,000.00 allocation. See details |
Education Department / Office of Special Education and Rehabilitative Services | 4/01/2009 | ||||||||||||||||||||||||
| CHEEKTOWAGA MARYVALE UNION FREE SCHOOL DISTRICT | $263,924.00 | Grant |
Special Education Grants to States, Recovery Act Assist States in providing special education and related services to children with disabilities in accordance with Part B of the IDEA
This spending item is part of a $759,193,000.00 allocation. See details |
Education Department / Office of Special Education and Rehabilitative Services | 4/01/2009 | ||||||||||||||||||||||||
| Imperial Wholesale Inc. | $263,000.00 | Loan | 504 Certified Development Loans TO ASSIST SMALL BUSINESS CONCERNS BY PROVIDING LONG TERM FINANCING THROUGH THE SALE OF DEBENTURES TO THE PRIVATE SECTOR | Small Business Administration | |||||||||||||||||||||||||
| TONAWANDA BOARD OF EDUCATION | $262,599.00 | Grant |
Special Education Grants to States, Recovery Act Assist States in providing special education and related services to children with disabilities in accordance with Part B of the IDEA
This spending item is part of a $759,193,000.00 allocation. See details |
Education Department / Office of Special Education and Rehabilitative Services | 4/01/2009 | ||||||||||||||||||||||||
| TRANSPORTATION, NEW YORK DEPARTMENT OF | $261,041.00 | Grant | Highway Planning and Construction Highway Infrastructure Investment Grant: Available for Use in Any Area (flexible) | Transportation Department / Federal Highway Administration | 5/26/2009 | ||||||||||||||||||||||||
| HEALTH RESEARCH, INC. | $256,057.00 | Grant | Trans-NIH Recovery Act Research Support A critical component of the acute inflammatory response is the rapid mobilization of blood-borne lymphocytes into secondary lymphoid organs. These organs are the staging ground for lymphocyte encounters with antigens and foreign pathogens during the initiation of protective immunity. Significant progress has been achieved in defining the adhesion events that guide homeostatic steady-state trafficking of lymphocytes across vascular checkpoints in lymphoid organs. By contrast, the molecular basis of inducible trafficking of na+»ve and central memory cells to lymphoid organs during inflammation is poorly understood. Extensive preliminary data lead us to hypothesize that the proinflammatory cytokine, interleukin-6 (IL-6), is a driving force in regulating lymphocyte migration into lymphoid organs during acute inflammation. The first aim will identify the cellular source of IL-6 that regulates the capture efficiency of vascular gateways in a model of systemic febrile inflammation. Reciprocal bone marrow chimeras with wild-type and IL-6-deficient mice will segregate whether IL-6 production by radiation-resistant stromal cells or radiation-sensitive hematopoietic cells is required for enhanced lymphocyte trafficking across vessel walls during febrile stress. Homing assays and intravital microscopy will validate whether radiation-sensitive hematopoietic cells or radiation-resistant stromal cells are the primary source of IL-6 that promotes lymphocyte influx into lymphoid organs. Aim 2 will focus on determining if IL-6 is also responsible for mobilizing the recruitment of na+»ve T cells to local inflamed lymph nodes during an adaptive immune response. These studies are based on our surprising discovery that IL-6 produced by mature dendritic cells (DC) modifies the adhesive properties of vascular entryways in draining nodes. Studies will determine whether DC act distally (at inflammatory sites) or locally (in draining lymph node) to regulate vascular endothelial adhesion. Understanding the cytokine requirements for lymphocyte recruitment during acute inflammation may lead to novel intervention strategies in chronic inflammatory disorders as well as provide insights into vaccine approaches based on the ability of cytokines to heighten adaptive immunity.... Show more | Health and Human Services, Department of / National Institutes of Health | 7/21/2009 | ||||||||||||||||||||||||
| MULTIPLE RECIPIENTS | $251,471.00 | Loan | Very Low to Moderate Income Housing Loans - Guaranteed Single Family Housing Guaranteed Loans - ARRA | Agriculture Department / Rural Housing Service | |||||||||||||||||||||||||
| Buerk Tool LLC | $250,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| Gary D. Stromberg & Associates | $250,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| Construction and Service Solutions Corp. | $250,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| Phinney Acquisition Corp. | $250,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| Cenergy Marketing & Communications, LLC | $250,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| KEN-TON FABRICATORS, INC. | $250,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| Edward P. O'Brien, MD | $250,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| Emerling International Foods, Inc. | $250,000.00 | Loan | 7(a) Loan Guarantees PATRIOT EXPRESS | Small Business Administration | |||||||||||||||||||||||||
| Ievolve Inc | $250,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| JOHNNY ROCKETS | $250,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| HEALTH RESEARCH, INC. | $249,875.00 | Grant | Trans-NIH Recovery Act Research Support To analyze how immune responses generated against respiratory viral infection impact immunological and pathological responses to a subsequent pulmonary bacterial infection. Our goal is to identify the molecules and pathways involved in increased susceptibility or protection against subsequent infections. We will evaluate the interactions between two pathogens (respiratory syncytial virus and non-typeable Haemophilus influenzae) that have direct relevance to otitis media and chronic obstructive pulmonary disease. Our studies will determine whether the age of the host during primary exposure to RSV infection influences the generation of anti-NTHI immune responses.... Show more | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 | ||||||||||||||||||||||||
| HEALTH RESEARCH, INC. | $248,377.00 | Grant | Trans-NIH Recovery Act Research Support This proposal is being submitted in response to NOT-OD-09-058, titled 'NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications.' We propose to expand our NCI R25T funded postdoctoral training program in prevention with the adddition of one trainee capable of completing the program in two years. Our program is now at full capacity with four postdoctoral fellows; three are population scientists and one is a basic scientist. The fifth trainee will be a basic scientist who can use his/her expertise and contacts in the areas of chemoprevention and biomarkers while developing research skills in the behavioral, nutritional and/or social sciences. Our vision of cancer prevention at Roswell Park Cancer Institute (RPCI) is drawn from extending the 'bench to bedside' paradigm of translational research. Under the leadership of James Marshall, PhD, Senior Vice President for Cancer Prevention and Population Sciences (CPPS), it has been broadened into a 'bench to sidewalk' model, integrating basic bench, clinical, epidemiologic and population sciences. In this vision, prevention demands the translation of basic science as much as cancer treatment does. Prevention also requires that the basic bench sciences -- genetics, biochemistry and molecular biology -- be integrated with the sciences of prevention: epidemiology and population sciences. Our training program, based in CPPS, builds on Roswell Park's strengths: an established history of multidisciplinary collaboration; a strong group of mentors with numerous funded research projects; and collaboration with the University at Buffalo. The requested revision will use the infrastructure of our existing program to equip an additional basic scientist with the principles, methods and practices needed for cancer prevention research. Our comprehensive training program encourages and supports innovative transdisciplinary research and professional development. The proposed revision will meet the Recovery Act objectives of job creation and accelerating the pace of scientific research by employing a postdoctoral fellow for two years and by training that fellow to launch an independent research career.... Show more | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 | ||||||||||||||||||||||||
| ALDEN CENTRAL SCHOOL DISTRICT | $245,575.00 | Grant |
Special Education Grants to States, Recovery Act Assist States in providing special education and related services to children with disabilities in accordance with Part B of the IDEA
This spending item is part of a $759,193,000.00 allocation. See details |
Education Department / Office of Special Education and Rehabilitative Services | 4/01/2009 | ||||||||||||||||||||||||
| Aurora Audiology & Speech Associates In | $241,000.00 | Loan | 504 Certified Development Loans TO ASSIST SMALL BUSINESS CONCERNS BY PROVIDING LONG TERM FINANCING THROUGH THE SALE OF DEBENTURES TO THE PRIVATE SECTOR | Small Business Administration | |||||||||||||||||||||||||
| TRANSPORTATION, NEW YORK DEPARTMENT OF | $240,000.00 | Grant | Highway Planning and Construction Highway Infrastructure Investment Grant: Available for Use in Any Area (flexible) | Transportation Department / Federal Highway Administration | 5/26/2009 | ||||||||||||||||||||||||
| ISLANDVIEW HOUSING DEVELOPMENT | $238,368.00 | Grant | Section 8 Housing Assistance Payments Program Special Allocations (Recover Contract Svs S8 Funds | Housing and Urban Development Department / Federal Housing Commissioner | |||||||||||||||||||||||||
| BRYANT & STRATTON COLLEGE INC | $238,166.00 | Grant | Federal Pell Grant Program GRANT PROGRAM | Education Department / DOED - Student Financial Assistance Programs | |||||||||||||||||||||||||
| NEIGHBORHOOD LEGAL SERVICE INC | $235,900.00 | Grant |
Homelessness Prevention and Rapid Re-Housing Program (Recovery Act Funded) It is estimated that this program will be able to assist 825 clients per year or 2,474 over the 3 year period of the grant.
This spending item is part of a $6,594,080.00 allocation. See details |
Housing and Urban Development Department / Community Planning and Development | 8/13/2009 | ||||||||||||||||||||||||
| HAUPTMAN WOODWARD MEDICAL RESEARCH INSTITUTE, INC. | $235,561.00 | Grant | Trans-NIH Recovery Act Research Support An administrative supplement was awarded on 30 September 2009 for our R01 research grant entitled, 'Structures of Peptide Synthetases and Related Enzymes'. Our research focus is on a family of enzymes called Non-Ribosomal Peptide Synthetases (NRPSs). These moduular enzymes catalyze the synthesis of pharmaceutically important peptide antibiotics and anticancer agents, as well as peptide virulence factors that are important for bacterial survival. In the modular catalytic strategy employed by the NRPS enzymes, the peptide building blocks are passed from active site to active site in an assembly line manner, requiring coordinated conformational rearrangements of the NRPS domains. Our research aims are to understand this modular catalytic strategy. In particular, we will use biochemical and structural techniques to identify the conformational changes that allow the delivery of synthetic intermediates to the requisite active sites. Additionally, we will investigate the use of small molecule inhibitors that can block the NRPS catalysis. These chemical probes will serve as useful tools for structural studies. These compounds will also serve as initial leads for the development of novel antibiotics as they will be designed to block the NRPS synthesis of bacterial virulence factors. Specifically, funds from the American Recovery and Reinvestment Act will be used as partial salary support of the PI, a research technician, and two graduate students. Funds will also be used for research supplies, travel to scientific conferences, and synchrotron X-ray facilities for data collection. The ARRA funds will accelerate the pace of our research, allowing us to investigate NRPS clusters from additional genetic sources such as the human pathogens Pseudomonas aeruginosa and Acinetobacter baumannii. The identification of the catalytic mechanisms and of the synthetic pathways of these novel systems will generate new strategies for the control of bacterial pathogens.... Show more | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 | ||||||||||||||||||||||||
| BUFFALO CITY SCHOOL DISTRICT | $230,769.00 | Grant |
Child Nutrition Discretionary Grants Limited Availability The New York State Education Department received funds through the American Recovery and Reinvestment Act of 2009 (ARRA) to assist in the purchase of equipment for School Food Authorities (SFAs) participating in the National School Lunch Progrram (NSLP) through a competitive grant process. Priority was given to SFAs for equipment in schools in which at least 50 percent of the students were eligible for free or reduced- priced meals. Other focused areas of the grant included: improving the quality of school foodservice meals to meet the dietary guidelines; improving the safety of food served in the school meal programs; improving the overall energy efficiency of the school foodservice operations; and supporting the expansion of participation in the school meal program. To date the NYS Education Department has: 1. Issues an ARRA grant solicitation to SFAs participating in the NSLP 2. Received and scored ARRA grant applications from SFAs competitively 3. Awarded ARRA grants to SFAs participating in the NSLP... Show more
This spending item is part of a $5,990,470.00 allocation. See details |
Agriculture Department / Food and Nutrition Service | 7/06/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $230,464.00 | Grant | Trans-NIH Recovery Act Research Support The primary objective of the proposed research is to develop a rodent model of self administration (SA) in which drug consumption has delayed negative consequences. Self administration procedures in which the animals make responses that are reinforced by IV druug injections are widely used and are perhaps the most convincing non-human animal models of drug abuse. Non-human animal SA models, however, may not model important aspects of human drug SA. In humans, impulsivity is considered an important component of drug abuse because individuals take drugs despite the knowledge of negative (often delayed) outcomes associated with drug use. In contrast, standard laboratory animal models of SA have no explicit negative outcomes associated with the SA of the drug. Because there are currently no SA models that incorporate negative consequences, the impact of negative outcomes is not generally incorporated into current ideas about the underlying behavioral and neurobiological mechanisms mediating drug abuse. The goal of the Experiment 1 of this application is to determine a dose of cocaine and an amount of water that have equivalent reinforcing efficacy. In this application reinforcing efficacy is measured using progressive ratio schedules of reinforcement. In progressive ratio schedules, reinforcement efficacy is operationally defined as the break point (BP) which indicates the maximum number of responses an animal will make on a progressive ratio schedule of reinforcement for a given reinforcer. Determination of a dose of cocaine and an amount of water that have equivalent efficacy will insure that cocaine and water reinforcers of equivalent reinforcing efficacy are used In Experiments 2 and 3. Experiment 2 will determine if immediate shock has different effects on the reinforcing efficacy of drug and natural reinforcers using the progressive ratio schedule of reinforcement. Building upon Experiments 1 and 2, Experiment 3 will determine the effects of delaying the shock on the reinforcing efficacy of the cocaine/shock and water/shock reinforcers. These studies will advance to our understanding of drug abuse by determining if punishment or delays to punishment have similar (or dissimilar) effects on drug (cocaine) and natural (water) reinforcers of equivalent reinforcing efficacy. These results will help to determine if a 'punished' SA model is a valuable tool with which to investigate the behavioral and cognitive regulation of drug abuse by negative consequences. PUBLIC HEALTH RELEVANCE: The primary objective of the proposed research is to develop a rodent model of self administration (SA) in which drug consumption has delayed negative consequences. There is little doubt that non-human animal SA procedures model important aspects of drug taking in humans; however in some respects the typical application of this model in the laboratory does not model important aspects of drug consumption by human addicts. According to the Diagnostic and Statistical Manual of Mental Disorders (APA, 1994) an important characteristics of human drug addiction is continued drug intake despite harmful consequences. However, current non human animal models of drug abuse do not address this important issue. Consequently, the impact of negative outcomes is not generally incorporated into current ideas about the underlying behavioral and neurobiological mechanisms mediating drug abuse. We believe that drug abuse in humans is a function of two separate processes, 'rewarding' positive affective responses to the drug and 'impulsivity-related' factors, or influences that normally inhibit or limit the use of drugs. Development of a non human SA model that incorporates negative consequences will enhance research into 'impulsivity-related factors' that are necessary for drug abstinence... Show more | Health and Human Services, Department of / National Institutes of Health | 5/14/2009 | ||||||||||||||||||||||||
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $230,464.00 | Grant | Trans-NIH Recovery Act Research Support The primary objective of the proposed research is to develop a rodent model of self administration (SA) in which drug consumption has delayed negative consequences. Self administration procedures in which the animals make responses that are reinforced by IV druug injections are widely used and are perhaps the most convincing non-human animal models of drug abuse. Non-human animal SA models, however, may not model important aspects of human drug SA. In humans, impulsivity is considered an important component of drug abuse because individuals take drugs despite the knowledge of negative (often delayed) outcomes associated with drug use. In contrast, standard laboratory animal models of SA have no explicit negative outcomes associated with the SA of the drug. Because there are currently no SA models that incorporate negative consequences, the impact of negative outcomes is not generally incorporated into current ideas about the underlying behavioral and neurobiological mechanisms mediating drug abuse. The goal of the Experiment 1 of this application is to determine a dose of cocaine and an amount of water that have equivalent reinforcing efficacy. In this application reinforcing efficacy is measured using progressive ratio schedules of reinforcement. In progressive ratio schedules, reinforcement efficacy is operationally defined as the break point (BP) which indicates the maximum number of responses an animal will make on a progressive ratio schedule of reinforcement for a given reinforcer. Determination of a dose of cocaine and an amount of water that have equivalent efficacy will insure that cocaine and water reinforcers of equivalent reinforcing efficacy are used In Experiments 2 and 3. Experiment 2 will determine if immediate shock has different effects on the reinforcing efficacy of drug and natural reinforcers using the progressive ratio schedule of reinforcement. Building upon Experiments 1 and 2, Experiment 3 will determine the effects of delaying the shock on the reinforcing efficacy of the cocaine/shock and water/shock reinforcers. These studies will advance to our understanding of drug abuse by determining if punishment or delays to punishment have similar (or dissimilar) effects on drug (cocaine) and natural (water) reinforcers of equivalent reinforcing efficacy. These results will help to determine if a 'punished' SA model is a valuable tool with which to investigate the behavioral and cognitive regulation of drug abuse by negative consequences. PUBLIC HEALTH RELEVANCE: The primary objective of the proposed research is to develop a rodent model of self administration (SA) in which drug consumption has delayed negative consequences. There is little doubt that non-human animal SA procedures model important aspects of drug taking in humans; however in some respects the typical application of this model in the laboratory does not model important aspects of drug consumption by human addicts. According to the Diagnostic and Statistical Manual of Mental Disorders (APA, 1994) an important characteristics of human drug addiction is continued drug intake despite harmful consequences. However, current non human animal models of drug abuse do not address this important issue. Consequently, the impact of negative outcomes is not generally incorporated into current ideas about the underlying behavioral and neurobiological mechanisms mediating drug abuse. We believe that drug abuse in humans is a function of two separate processes, 'rewarding' positive affective responses to the drug and 'impulsivity-related' factors, or influences that normally inhibit or limit the use of drugs. Development of a non human SA model that incorporates negative consequences will enhance research into 'impulsivity-related factors' that are necessary for drug abstinence... Show more | Health and Human Services, Department of / National Institutes of Health | 5/14/2009 | ||||||||||||||||||||||||
| Bruce J. Hora | $230,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| Food Bank of Western New York Incorporated | $228,086.00 | Grant |
Emergency Food Assistance Program (Administrative Costs) The New York State Office of General Services received funds through the American Recovery and Reinvestment Act of 2009 (ARRA) to pay costs associated with the distribution of USDA foods donated for use in The Emergency Food Assistance Program (TEFAP). Such costs include (but are not limited to) storage, transportation, handling, processing, and distribution of such foods; as well as costs associated with determining and verifying beneficiary eligibility, record keeping, auditing, and other administrative procedures required for program participation. To date, The New York State Office of General Services has provided funds to organizations-such as food banks, food pantries, and soup kitchens-that administer the program at the local level.... Show more
This spending item is part of a $3,060,740.00 allocation. See details |
Agriculture Department / Food and Nutrition Service | 3/16/2009 | ||||||||||||||||||||||||
| Amton Auto and Truck, Inc | $225,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration | |||||||||||||||||||||||||
| MULTIPLE RECIPIENTS | $222,870.00 | Loan | Very Low to Moderate Income Housing Loans - Guaranteed Single Family Housing Guaranteed Loans - ARRA | Agriculture Department / Rural Housing Service | |||||||||||||||||||||||||
| BRYANT & STRATTON COLLEGE INC | $221,607.00 | Grant | Federal Pell Grant Program GRANT PROGRAM | Education Department / DOED - Student Financial Assistance Programs | |||||||||||||||||||||||||
| BIDCO MARINE GROUP INC. | $221,512.00 | Contract | Replacement of Lock Sils - Lower Operating and Guard Gates, Black Rock Lock, Buffalo, NY | U.S. Army Corps of Engineers / U.S. Army Corps of Engineers - civil program financing only | 7/28/2009 | ||||||||||||||||||||||||
| BOYS AND GIRLS CLUBS OF BUFFALO INC | $221,277.00 | Grant |
WIA Youth Activities WIA Youth $71,526,360.00, CFDA 17.259: To provide employment-related services and high quality work experience, including an expanded summer youth work experience component, to America's youth ages 14-24 to prepare them for the workplace. Expenditures: $41,582,896.96. WIA Dislocated Workers $66,368,188.00, CFDA 17.260: To provide a variety of work-related employment and training services, including job training opportunities, to laid-off individuals to support their reentry into the job market. Expenditures: $16,957,161.32. WIA Adult $31,516,111.00, CFDA 17.258: To provide a variety of work-related employment and training services, including job training opportunities, to unemployed or underemployed adults to support their entry or reentry into the job market. Expenditures: $8,160,711.44.... Show more
This spending item is part of a $169,411,000.00 allocation. See details |
Labor Department / Employment and Training Administration | 2/17/2009 | ||||||||||||||||||||||||
| Botanicus Inc. | $220,000.00 | Loan | 504 Certified Development Loans TO ASSIST SMALL BUSINESS CONCERNS BY PROVIDING LONG TERM FINANCING THROUGH THE SALE OF DEBENTURES TO THE PRIVATE SECTOR | Small Business Administration | |||||||||||||||||||||||||
| MVP DEVELOPMENT, INC. | $220,000.00 | Loan | 7(a) Loan Guarantees TO AID SMALL BUSINESSES WHICH ARE UNABLE TO OBTAIN FINANCING IN THE PRIVATE CREDIT MARKETPLACE | Small Business Administration |