Dollars for Profs
Dig Into University Researchers' Outside Income and Conflicts of Interest
Published Dec. 6, 2019
This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.
Conflict of Interest
Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.
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Kung Ping Lu
Beth Israel Deaconess Medical Center, Department: Na
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Pinteon Therapeutics, Inc.
Equity Interest - Non-publicly traded entity ( e.g., stock, stock option, or other ownership interest)
Pinteon Therapeutics, Inc. (“Pinteon”) has licensed a specified subset of patents related to Pin1. Because the research results could be relevant in identifying potentially new Pin1 downstream targets would be useful in developing diagnostics and therapeutics, and the investigator’s significant financial interest could directly and significantly affect the design, conduct, or reporting of the PHS-funded research, BIDMC has determined that the private equity constitutes a financial conflict of interest with the research for this grant under applicable PHS regulations (45 C.F.R. §50.601 et seq.).
Function and Regulation of the Phosphorylation-Specific Prolyl Isomerase Pin1
During last 10 years of this grant, we have identified a unique enzyme called Pin1 as a key regulator of cell signaling in breast and other cancers. The current proposal will investigate the role of Pin1 in controlling the function of breast cancer stem cells,a small subset of breast cancer cells that might be responsible for tumor growth, metastases and resistance to therapies. These studies would lead to a better understanding of the basic mechanisms of breast cancer development and might help develop new and more effective therapies to overcome cancer resistance to current therapies.
Filed on September 17, 2014.
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Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.
Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.
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