Dollars for Profs

Dig Into University Researchers' Outside Income and Conflicts of Interest

Published Dec. 6, 2019

This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.

Financial doc
Filing Type

Conflict of Interest

Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.

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Xiao Zhou

Beth Israel Deaconess Medical Center, Department: Na

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Disclosed Conflict of Interest with

Pinteon Therapeutics, Inc.

Disclosed Value
Listed Reason
Equity Interest - Non-publicly traded entity ( e.g., stock, stock option, or other ownership interest)

Pinteon Therapeutics, Inc., has licensed a specified subset of patents related to Pin1. Because the research results could be relevant in identifying potentially new Pin1 downstream targets would be useful in developing diagnostics and therapeutics, and the investigator’s significant financial interest could directly and significantly affect the design, conduct, or reporting of the PHS-funded research, BIDMC has determined that the private equity constitutes a financial conflict of interest with the research for this grant under applicable PHS regulations (45 C.F.R. §50.601 et seq.).

Listed Research Project
Function and Regulation of the Phosphorylation-Specific Prolyl Isomerase Pin1

During last 10 years of this grant, we have identified a unique enzyme called Pin1 as a key regulator of cell signaling in breast and other cancers. The current proposal will investigate the role of Pin1 in controlling the function of breast cancer stem cells,a small subset of breast cancer cells that might be responsible for tumor growth, metastases and resistance to therapies. These studies would lead to a better understanding of the basic mechanisms of breast cancer development and might help develop new and more effective therapies to overcome cancer resistance to current therapies.

Filed on September 17, 2014.

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Name Institution Type Company Disclosed Value
Xiao Zhou Beth Israel Deaconess Medical Center Conflict of Interest Pinteon Therapeutics Value cannot be readily determined
Xiao Zhou Beth Israel Deaconess Medical Center Conflict of Interest Pinteon Therapeutics, Inc. Value cannot be readily determined
If you see an error in the database or a reason we should not disclose a record, please contact us at [email protected] and we'll evaluate it on a case-by-case basis.
Sources: National Institutes of Health, public records requests filed at multiple public state universities

Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.

Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.

ProPublica obtained additional financial disclosures and conflict of interest forms that we have not yet digitized and added to the database. You can download those disclosures in the ProPublica Data Store.

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