Andrea Califano

Dr. Califano's anticipated equity interest in Darwin Health was originally reported as a managed FCOI in connection with this grant in FCOI Report 10941. As noted therein, Dr. Califano is co-founder of a startup company called Darwin Health. Columbia has determined that the company’s aims (commercialization of efforts for systematic identification of aberrantly activated gene products within critical tumor checkpoints that drive cancer initiation, progression, and drug resistance) are related to research described in this award; that the outcome of this research could affect the company or Dr. Califano’s significant financial interest in the company; and that the design, conduct, and/or reporting of research under this award could be affected by this financial interest.

Columbia now is reporting additional new financial interests for Dr. Califano in Darwin, which have been reviewed and incorporated into the existing management plan. Columbia had originally submitted a new FCOI Report on 5/21/18 (#14134) reporting these new financial interests. For administrative purposes (and after discussion with Kathy Hancock, OPERA Grants Compliance on 5/21/18), the following steps are being taken: (1) FCOI Report 14134 has been rescinded, (2) Columbia is reporting the FCOI described in FCOI Report 10941 as no longer existing, and (3) Columbia is consolidating the reporting of all of Dr. Califano’s Darwin financial interests and the FCOI management for this award into this new FCOI report #14138.