Johnson County, Iowa, funds by Health and Human Services, Department of
Listing $64,186,421.03 in stimulus funds from Health and Human Services, Department of for Johnson
Note: For some programs where states do not report where money will be distributed across the state, we do not have the allocation for individual counties. Those programs include: Medicaid, unemployment benefits and food stamps. Those amounts are included in the totals for where the state agency receiving that money is located.
Amount refers to both the amount of stimulus funding going toward the project and the face value of the loan.
| Recipient | Amount | Description | Federal Dept./Agency | Date |
|---|---|---|---|---|
| UNIVERSITY OF IOWA, THE | $7,969,325 | Trans-NIH Recovery Act Research Support The University of Iowa is requesting funds to support the purchase of a state-of-the-art Siemens seven Tesla whole body MRI system to support the research efforts of 33 funded NIH investigators from five colleges (Medicine, Engineering, Public Health, Lib | National Institutes of Health | 7/01/2010 |
| UNIVERSITY OF IOWA, THE | $1,587,504 |
Trans-NIH Recovery Act Research Support Dystroglycan is a widely expressed transmembrane glycoprotein that acts as a high- affinity receptor for both extracellular matrix proteins containing laminin-G domains and certain arenaviruses. Secondary dystroglycanopathies encompass a collection of mus
This spending item is part of a $2,536,301 allocation.
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|
National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF IOWA, THE | $1,576,739 | Trans-NIH Recovery Act Research Support Schizophrenia is a major mental disorder that strikes in young adulthood and that has a heritability of 80-90%. Even with state-of-the-art treatment, schizophrenia often produces life-long disability, creating a pressing need to delineate the heritable co | National Institutes of Health | 5/14/2009 |
| UNIVERSITY OF IOWA, THE | $1,450,000 | Trans-NIH Recovery Act Research Support The University of Iowa Holden Comprehensive Cancer Center (HCCC), a matrix cancer center at the University of Iowa, is applying for renewal of its Cancer Center Support grant. This is the first competitive renewal application for the HCCC. The Cancer Cent | National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF IOWA, THE | $1,339,161 |
Recovery Act Comparative Effectiveness Research - AHRQ The risk-benefit balance of antipsychotic use in dementia is precarious. While evidence supports the efficacy of certain atypical antipsychotics in treating behavioral disturbances, these drugs have been found to increase the risk of death and cecerebrovasc... Show more
This spending item is part of a $1,416,381 allocation.
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|
Agency for Healthcare Research and Quality | 9/30/2010 |
| UNIVERSITY OF IOWA, THE | $1,302,240 | Trans-NIH Recovery Act Research Support Long-temn alcohol consumption progressively leads to multiple immune defects. Chronic alcoholics display lesions in both innate and adaptive immunity, and experience increased rates of bacterial and viral infection. Of particular interest, extended alcoho | National Institutes of Health | 8/20/2009 |
| UNIVERSITY OF IOWA, THE | $998,944 | Trans-NIH Recovery Act Research Support This application addresses two broad Challenge Areas and three associated specific Challenge Topics including: i) the broad Challenge Area (06) Enabling Technologies, specific Challenge Topic 06-HL- 105: Develop transgenic animal models that are informati | National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF IOWA, THE | $997,575 | Trans-NIH Recovery Act Research Support An essential element of the RFA entitled Institutional Clinical and Translational Science Award, CTSA, is the creation of an academic home that is a department, center, or institute. In response to the RFA, the University of Iowa will create The Universit | National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF IOWA, THE | $996,755 | Trans-NIH Recovery Act Research Support Although some degree of gradual cognitive decline is nearly universal and a normal part of the aging process, previous research by our group has shown that age-related cognitive decline is amenable to intervention. Building on speed of processing theory, | National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF IOWA, THE | $952,778 |
Trans-NIH Recovery Act Research Support Treatment rates vary dramatically across patients grouped by race, age, and gender. If treatment effects are heterogeneous across patients, though, it is not clear from treatment rate comparisons alone whether treatment rates should be increased or decrea
This spending item is part of a $1,458,033 allocation.
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|
National Institutes of Health | 9/24/2010 |
| UNIVERSITY OF IOWA, THE | $944,475 |
Trans-NIH Recovery Act Research Support This research addresses the need for innovative bioreactor design. Bioreactors are laboratory systems that precisely control mechanical forces and environmental conditions on biologically changing tissues for periods of several hours to many days. Some bi
This spending item is part of a $1,376,400 allocation.
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|
National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF IOWA, THE | $940,370 | Trans-NIH Recovery Act Research Support This research project will investigate the predictors and outcomes of preschool age children's first preventive dental visit, improving our understanding of how age at first preventive dental visit is affected by the psychosocial, behavioral, and social f | National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF IOWA, THE | $871,127 |
Trans-NIH Recovery Act Research Support This topic specifically targets developing a deep and diverse understanding of genetic maps and recombination within and between species, which is what our proposal intends to study. Project Title: Fine-scale recombination rate variation within and betwee
This spending item is part of a $1,834,345 allocation.
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|
National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF IOWA, THE | $814,755 | Trans-NIH Recovery Act Research Support Previous research suggests that an approach that includes a combination of acoustic and electrical stimulation within the same ear can be particularly effective for this group of hearing impaired listeners (von Ilberg et al., 1999; Gantz and Turner, 2003; | National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF IOWA, THE | $792,858 |
Trans-NIH Recovery Act Research Support A fundamental assumption in viral research is that viral genes confer pathogenicity. Viral genetics is essential to understanding viral disease, but genetic approaches assume that one knows what genes the virus has. If a virus is significantly more comp
This spending item is part of a $1,911,255 allocation.
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|
National Institutes of Health | 9/11/2009 |
| UNIVERSITY OF IOWA, THE | $786,645 |
Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (01) Behavior, Behavioral Change, and Prevention and specific Challenge Topic, 01-GM-104: Mechanisms of Behavior Change Research. Disclosing the prospect or discovery of genomic IFs to clinical patients or p
This spending item is part of a $847,690 allocation.
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|
National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF IOWA, THE | $781,686 | Trans-NIH Recovery Act Research Support This application addresses Broad Challenge Area (5), Comparative Effectiveness Research, and specifically Comparative Effectiveness Research on Cancer Screening, 05-CA-102. Significance: With our health care system in financial crisis, and colorectal canc | National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF IOWA, THE | $750,000 | Trans-NIH Recovery Act Research Support Pancreatic involvement is common and the injury progresses to pancreatic insufficiency (PI) in the majority of patients with cystic fibrosis (CF). Currently, there are no treatments to halt the progression of pancreatic disease in CF and the exact mechani | National Institutes of Health | 9/16/2009 |
| UNIVERSITY OF IOWA, THE | $750,000 | Trans-NIH Recovery Act Research Support The magnitude and the duration of cytokine action are essential in determining the response to foreign antigens and allergens. Thus, the action of cytokines is tightly regulated both developmentally and within the cell. The Suppressor of Cytokine Signalin | National Institutes of Health | 5/21/2009 |
| UNIVERSITY OF IOWA, THE | $750,000 | Trans-NIH Recovery Act Research Support Klebsiella pneumoniae is an opportunistic pathogen frequently implicated in respiratory and urinary tract infections of hospitalized patients. In addition, it is a leading cause of pneumonia in chronic alcoholics and has also been associated with communit | National Institutes of Health | 5/06/2009 |
| UNIVERSITY OF IOWA, THE | $748,412 | Trans-NIH Recovery Act Research Support This study is designed to improve access to appropriate behavioral services for young children (ages 1 to 6 years) with autism spectrum disorders. The major research goal is to evaluate the effectiveness and efficiency of conducting behavioral treatment f | National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF IOWA, THE | $746,117 |
Trans-NIH Recovery Act Research Support The molecular mechanisms underlying uterine smooth muscle excitation during pregnancy are unknown, and this deficit has hampered the development of effective therapies for uterine dysfunction. The maintenance of uterine quiescence during pregnancy require
This spending item is part of a $924,818 allocation.
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|
National Institutes of Health | 8/27/2009 |
| UNIVERSITY OF IOWA, THE | $745,884 | Trans-NIH Recovery Act Research Support Severe sepsis is a systemic response to infection that culminates in acute organ failure. Preclinical models of sepsis demonstrate that a disturbed microvasculature characterized by hyporesponsive vessels and heterogeneous flow contributes to organ failur | National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF IOWA, THE | $737,534 | Trans-NIH Recovery Act Research Support Insulators are elements required for transcriptional fidelity in eukaryotic genomes. Prevailing models suggest that insulators are structural components that divide chromosomes into loop domains to constrain enhancer and silencer action. The goal of our s | National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF IOWA, THE | $726,998 |
Trans-NIH Recovery Act Research Support HIV disease progression varies widely among individuals. Although some genetic or HIV protein factors have been identified that affect disease progression, these do not explain slow HIV disease progression in most cases. We and others found an association
This spending item is part of a $1,057,464 allocation.
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|
National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF IOWA, THE | $702,165 |
Trans-NIH Recovery Act Research Support This application addresses the broad Challenge Area (05) Comparative Effectiveness Research and the specific Challenge Topic: 05-NS-104* Intervention vs. Best Medical Therapy in Asymptomatic Persons With Identified Vascular Abnormalities. The Internationa
This spending item is part of a $967,907 allocation.
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|
National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF IOWA, THE | $694,682 |
Lung Health Study in the Agriculture Health Study. SSS will provide support for conducting a case-cohort study of approximately 1338 currently symptomatic asthmatic cases (prevalent and incident cases) and 1508 randomly selected cohort members as controls
This spending item is part of a $7,600,000 allocation.
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|
National Institutes of Health | 3/24/2010 |
| UNIVERSITY OF IOWA, THE | $667,195 | Trans-NIH Recovery Act Research Support A major stated research priority of the National Eye Institute is 'to identify the genes involved in retinal degenerative diseases'. Although numerous genes causing retinal degeneration have been discovered, many remain to be identified, and novel approac | National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF IOWA, THE | $658,627 | Trans-NIH Recovery Act Research Support Our general aim is to discover how the brain processes visual information, how neural activity is related to visual perception, and how visual processing interacts with other brain systems underlying cognition. Our specific aim is to elucidate how pigeons | National Institutes of Health | 9/02/2009 |
| UNIVERSITY OF IOWA, THE | $627,422 |
Trans-NIH Recovery Act Research Support S. enterica serovar Typhimurium is an important human pathogen causing acute gastroenteritis following ingestion of contaminated food. One of the major vehicles of infection for humans is contaminated poultry because the bacteria easily infect these anima
This spending item is part of a $764,300 allocation.
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|
National Institutes of Health | 5/07/2009 |
| UNIVERSITY OF IOWA, THE | $625,710 |
Trans-NIH Recovery Act Research Support The University of Iowa Holden Comprehensive Cancer Center (HCCC), in collaboration with the Iowa Cancer Consortium (ICC), the Iowa Center for Education and Research on Therapeutics (CERT) and the Iowa Research Network (IRENE), propose development of a com
This spending item is part of a $1,000,000 allocation.
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|
National Institutes of Health | 8/30/2010 |
| UNIVERSITY OF IOWA, THE | $617,103 | Trans-NIH Recovery Act Research Support Juvenile Polyposis (JP) is an autosomal dominant syndrome predisposing to the development of hamartomatous polyps of the colon, rectum, and stomach. Affected patients have an approximately 50% risk of developing gastrointestinal cancer. Work in our labora | National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF IOWA, THE | $611,004 | Trans-NIH Recovery Act Research Support Chronic alcoholism increases the incidence and severity of respiratory diseases and infections. Indeed, alcoholics compared to non-alcoholic individuals have increased mortality and morbidity during bacterialpneumonias. While much is known about the role | National Institutes of Health | 8/20/2009 |
| UNIVERSITY OF IOWA, THE | $599,757 | Trans-NIH Recovery Act Research Support An essential element of the RFA entitled Institutional Clinical and Translational Science Award, CTSA, is the creation of an academic home that is a department, center, or institute. In response to the RFA, the University of Iowa will create The Universit | National Institutes of Health | 9/03/2009 |
| UNIVERSITY OF IOWA, THE | $581,057 | Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (15) Translational Science and specific Challenge Topic, 15- ES-101*: Effects of Environmental Exposures on Phenotypic Outcomes Using Non-Human Models. Farmers as a group have the highest occupational risk f | National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF IOWA, THE | $580,999 | Trans-NIH Recovery Act Research Support Multiple myeloma (MM) is still incurable - causing the death of 10,000 Americans annually. Currently, glucocorticoids and the proteasome-inhibiting drug PS-341 (Bortezomib/Velcade) rank among the most effective agents in myeloma therapy. Given that MM is | National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF IOWA, THE | $568,017 | Trans-NIH Recovery Act Research Support The recycling endosome (RE) is a nexus for membrane transport in both polarized and nonpolarized cells. In polarized cells, endocytic traffic originating on both the apical and basolateral surfaces passes through the recycling endosome. Basolateral secret | National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF IOWA, THE | $559,935 |
Recovery Act Comparative Effectiveness Research - AHRQ Enhanced Data to Accelerate Complex Patient Comparative Effectiveness Research-It is our premise that easy to use data products will accelerate meaningful comparative effectiveness research (CER). Claims data are extremely difficult to use, requiuiring exte... Show more
This spending item is part of a $882,960 allocation.
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|
Agency for Healthcare Research and Quality | 7/29/2010 |
| UNIVERSITY OF IOWA, THE | $548,213 | Trans-NIH Recovery Act Research Support Tumor suppressor genes (TSGs) elicit carcinogenic phenotypes by gene loss. In thousands of publications, however, TSGs have been assayed for activities by reintroduction into tumor cells with TSG deletions. Whereas the FHIT gene has been defined as a gene | National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF IOWA, THE | $536,296 | Trans-NIH Recovery Act Research Support We have just completed a Phase I dose/toxicity trial for children and young adults with recurrent solid tumors using 90Y-DOTA-tyr3-Octreotide (90Y-DOTATOC) to target the somatostatin receptor type 2 (sst2) expressed on tumor cells. Potential subjects were | National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF IOWA, THE | $519,784 | Trans-NIH Recovery Act Research Support Recent advances in the field of structural biology and quantitative proteomics mean that there is now sufficient information available to allow the construction of meaningful, working molecular models of physiological environments. Such environmental mode | National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF IOWA, THE | $501,049 |
Trans-NIH Recovery Act Research Support Rheumatoid arthritis (RA) remains a major unmet medical need despite recent advances in therapy. The pain and loss of function resulting from chronic synovitis are due to a variety of influences, including activated adaptive and innate immune responses. I
This spending item is part of a $893,569 allocation.
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National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF IOWA, THE | $500,000 | Trans-NIH Recovery Act Research Support The Zeiss LSM 710 Laser Scanning Confocal Microscope will be a critical tool for NIH investigators at the University of Iowa. The proposed microscope will replace a failing system that over the past 18 months has supported the confocal imaging needs of 55 | National Institutes of Health | 4/28/2009 |
| UNIVERSITY OF IOWA, THE | $498,000 | Trans-NIH Recovery Act Research Support Rituximab is widely used as a therapy for B cell malignancies. Despite its certain clinical value, the mechanisms responsible for the clinical anti-tumor effect of rituximab and other monoclonal antibodies (mAb) are unclear. Both antibody-dependent cellul | National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF IOWA, THE | $493,959 |
Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (15): 15-NS-103, 'Demonstration of 'proof-of-concept' for a new therapeutic approach in a neurological disease.' Children with inherited lysosomal storage disorders (LSDs) affecting the central nervous syste
This spending item is part of a $996,035 allocation.
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National Institutes of Health | 9/24/2009 |
| ADVANCED BIOMEDICAL INFORMATICS GROUP, L.L.C. | $489,784 |
Trans-NIH Recovery Act Research Support PREDICT-HD is an international 30-site observational study of persons at-risk for Huntington's disease (HD). PREDICT-HD capitalizes on two unique aspects of HD among neurodegenerative disorders the ability to know in advance who will develop the disease a
This spending item is part of a $582,540 allocation.
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|
National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF IOWA, THE | $488,985 | Trans-NIH Recovery Act Research Support The parent project long-term goal is to explore the therapeutic potential of up-regulating 5-sarcoglycan levels for the treatment of limb-girdle muscular dystrophy type 2D (LGMD2D). Mutations in the 1-sarcoglycan gene cause LGMD2D, and leads to progressiv | National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF IOWA, THE | $454,648 |
Trans-NIH Recovery Act Research Support Nontypeable Haemophilus influenzae (NTHi) commonly colonize the mucosal surfaces of the human upper respiratory tract. For the most part, this species resides in that environment in a benign (symbiotic?) relationship with the human host. With pathophysi
This spending item is part of a $648,648 allocation.
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National Institutes of Health | 8/01/2009 |
| UNIVERSITY OF IOWA, THE | $415,969 | Recovery Act Comparative Effectiveness Research - AHRQ This aims of this research are to assess the comparative effectiveness of Moderate-Dose and High-Dose Statins on cardiovascular event free survival; side-effect risk; and healthcare costs in complex AMI patients. This research will (1) exploit ththe large n... Show more | Agency for Healthcare Research and Quality | 9/30/2010 |
| UNIVERSITY OF IOWA, THE | $412,500 | Trans-NIH Recovery Act Research Support Mouse models of human psychiatric disorders show that chronic stress can lead to depression. Mice lacking 5HT2CR show signs of stress response, hyperactivity, increased appetite and obesity. 5HT2CR mRNA is edited by two enzymes ADAR1 and ADAR2 that belong | National Institutes of Health | 5/22/2009 |
| UNIVERSITY OF IOWA, THE | $412,432 | Trans-NIH Recovery Act Research Support The Leishmania spp. protozoa have a profound effect on the host cell that they invade. These parasites reside intracellularly usually in macrophages, a cell type with the capacity to kill intracellular microbes. Rather than succumb to microbicidal mechani | National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF IOWA, THE | $410,700 | Trans-NIH Recovery Act Research Support Human coronaviruses (HCoVs) are positive-stranded RNA viruses that are estimated to account for approximately 30% of cases of the common cold. The emergence of a novel HCoV as the etiologic agent of severe acute respiratory syndrome (SARS) demonstrated th | National Institutes of Health | 6/04/2009 |
| UNIVERSITY OF IOWA, THE | $408,247 | Trans-NIH Recovery Act Research Support Staphylococcus aureus is one of the most common causes of acute and chronic infections in both community and hospital settings. The ability of S. aureus to adhere to host tissues or medical implants and develop into biofilms is a critical determinant of c | National Institutes of Health | 5/29/2009 |
| UNIVERSITY OF IOWA, THE | $401,778 | Trans-NIH Recovery Act Research Support According to the CDC, healthcare-associated infections affect about two million patients in American hospitals each year. Infections like influenza and MRSA routinely spread to and among hospitalized patients, often via healthcare workers. To better under | National Institutes of Health | 6/18/2009 |
| UNIVERSITY OF IOWA, THE | $400,000 | Trans-NIH Recovery Act Research Support An essential element of the RFA entitled Institutional Clinical and Translational Science Award, CTSA, is the creation of an academic home that is a department, center, or institute. In response to the RFA, the University of Iowa will create The Universit | National Institutes of Health | 9/04/2009 |
| UNIVERSITY OF IOWA, THE | $385,700 |
Trans-NIH Recovery Act Research Support The filoviruses, Ebola (EBOV) and Marburg (MARV), cause periodic hemorrhagic fever outbreaks in sub-Saharan Africa.-? Because of the high rates of mortality associated with these infections and high transmissibility of these viruses in the human populatio
This spending item is part of a $423,450 allocation.
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National Institutes of Health | 5/21/2009 |
| UNIVERSITY OF IOWA, THE | $378,341 |
Trans-NIH Recovery Act Research Support The Severe Acute Respiratory Syndrome, caused by a novel coronavirus (SARS-CoV), resulted in substantial morbidity and mortality in 2002-2003. With the lack of recurrence of SARS, research efforts to develop an effective vaccine have largely halted. Howev
This spending item is part of a $403,341 allocation.
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National Institutes of Health | 9/11/2009 |
| UNIVERSITY OF IOWA, THE | $376,437 |
Trans-NIH Recovery Act Research Support This Challenge grant application addresses the Broad challenge area: translational science: Specific challenge topic: 15-NS-103. Demonstration of proof of concept for a new therapeutic approach in a neurological disease. Our goal is to utilize a new conce
This spending item is part of a $989,410 allocation.
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National Institutes of Health | 9/29/2009 |
| Iowa Consortium For Comprehensive Cancer Control | $374,290 |
Trans-NIH Recovery Act Research Support The University of Iowa Holden Comprehensive Cancer Center (HCCC), in collaboration with the Iowa Cancer Consortium (ICC), the Iowa Center for Education and Research on Therapeutics (CERT) and the Iowa Research Network (IRENE), propose development of a com
This spending item is part of a $1,000,000 allocation.
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National Institutes of Health | 8/30/2010 |
| UNIVERSITY OF IOWA, THE | $374,100 | Trans-NIH Recovery Act Research Support The proper functioning of the immune system requires a delicate and complex balance between cellular activation and programmed cell death, maintained by signals to cells delivered through families of receptors that deliver information from other cells and | National Institutes of Health | 7/06/2010 |
| UNIVERSITY OF IOWA, THE | $371,938 | Trans-NIH Recovery Act Research Support The host response to pathogenic insults involves complex inflammatory responses and cellular immune reactions, such that the decision to generate protective immunity or tolerance often depends on the context in which T cells first encounter antigen (Ag). | National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF IOWA, THE | $366,686 | Trans-NIH Recovery Act Research Support This proposal addresses the broad subject area, Biomarker Discovery and Validation and the specific challenge topic, Biomarkers of Persistent Damage After Acute Joint Injury (03-AR-101). Our proposal entitled 'Biomarkers of the Risk for Post-Traumatic Ost | National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF IOWA, THE | $357,725 | Trans-NIH Recovery Act Research Support The application is targeted to hire a postdoc that would be unemployed starting July 1st 2009 and to expand the number of PIs by adding two new faculty to the portfolio of investigators to accomplish a new scientific objective. In addition, the revision w | National Institutes of Health | 9/09/2009 |
| UNIVERSITY OF IOWA, THE | $356,337 |
Trans-NIH Recovery Act Research Support Stimulant abuse (including both cocaine and amphetamines) is a serious public health problem. There are thought to be over 3 million current users of these drugs in the United States, and these drugs account for numerous emergency room visits each year. A
This spending item is part of a $418,403 allocation.
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National Institutes of Health | 5/14/2009 |
| UNIVERSITY OF IOWA, THE | $333,330 | Trans-NIH Recovery Act Research Support In many age-related neurodegenerative diseases, neuronal loss is correlated with the presence of hyperphosphorylated tau. In Alzheimer's disease, it has been hypothesized that neurons die because cell cycle mechanisms have been activated. In support of th | National Institutes of Health | 6/08/2009 |
| DIGITAL ARTEFACTS LLC | $325,110 |
Trans-NIH Recovery Act Research Support The Marian Koshland Science Museum of the National Academy of Sciences will produce two module exhibits (modules) that emphasize the use of scientific information in decision making and are aimed at a teen and adult audience. The topic matter of the modu
This spending item is part of a $931,200 allocation.
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National Institutes of Health | 7/16/2010 |
| UNIVERSITY OF IOWA, THE | $317,087 | Trans-NIH Recovery Act Research Support The recent emergence of specialty cardiac hospitals has generated widespread controversy. Proponents suggest that such hospitals deliver higher quality and lower cost care, while critics contend that specialty lospitals cherry pick lower severity and more | National Institutes of Health | 8/10/2009 |
| UNIVERSITY OF IOWA, THE | $309,420 |
Trans-NIH Recovery Act Research Support This award is a supplement to award GM07966301. Post-translational histone modifications are essential to the proper regulation of nearly all DNA-mediated processes, whereas improper modifications lead to numerous disease states. Histone modifications e
This spending item is part of a $450,433 allocation.
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National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF IOWA, THE | $300,000 | Trans-NIH Recovery Act Research Support The development of effective gene therapies for inherited disorders requires interdisciplinary programs that focus on the identification of disease genes, an elucidation of disease pathogenesis, and the development of technologies for genetic modulation. | National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF IOWA, THE | $298,623 | Trans-NIH Recovery Act Research Support The University of Iowa Holden Comprehensive Cancer Center (HCCC), a matrix cancer center at the University of Iowa, is applying for renewal of its Cancer Center Support grant. This is the first competitive renewal application for the HCCC. The Cancer Cent | National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF IOWA, THE | $298,575 | Trans-NIH Recovery Act Research Support PREDICT-HD is an international 30-site observational study of persons at-risk for Huntington's disease (HD). PREDICT-HD capitalizes on two unique aspects of HD among neurodegenerative disorders the ability to know in advance who will develop the disease a | National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF IOWA, THE | $297,121 | Trans-NIH Recovery Act Research Support Animal studies show that prenatal maternal stress (PNMS) results in maternal glucocorticoids passing the placental barrier and disrupting fetal brain development, particularly the hypothalamic-pituitary-adrenal axis. This in turn influences pregnancy outc | National Institutes of Health | 6/08/2009 |
| UNIVERSITY OF IOWA, THE | $295,886 | Trans-NIH Recovery Act Research Support An essential element of the RFA entitled Institutional Clinical and Translational Science Award, CTSA, is the creation of an academic home that is a department, center, or institute. In response to the RFA, the University of Iowa will create The Universit | National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF IOWA, THE | $279,765 | Trans-NIH Recovery Act Research Support An essential element of the RFA entitled Institutional Clinical and Translational Science Award, CTSA, is the creation of an academic home that is a department, center, or institute. In response to the RFA, the University of Iowa will create The Universit | National Institutes of Health | 8/05/2010 |
| UNIVERSITY OF IOWA, THE | $263,657 | Trans-NIH Recovery Act Research Support The reduction in dental caries over the past 30+ years has been remarkable and started largely with the introduction of fluoride to the water supply. Increased access to dental care, improved oral hygiene, fluoride incorporation into professional dental p | National Institutes of Health | 5/29/2009 |
| UNIVERSITY OF IOWA, THE | $250,000 | ARRA Strengthening Communities Fund ARRA Strengthening Communities Fund State, Local, and Tribal Government Capacity Building Program. The goal of the program is to build our capacity to partner with community-based and faith-based non-profits and to provide training and technical assistanc | Administration for Children and Families | 9/23/2009 |
| UNIVERSITY OF IOWA, THE | $249,490 | Trans-NIH Recovery Act Research Support The hair cell, located in the inner ear, is an essential component of the hearing process. The actin cytoskeleton plays a major role in hair cell function, through both the actin filament bundle in the stereocilium and the actin web in the cuticular plate | National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF IOWA, THE | $245,840 | Trans-NIH Recovery Act Research Support Linguistic and psychological theory coupled with empirical studies on the heritability of individual differences in language development and language disorders support the hypothesis that the capacity for language development in humans is genetically infl | National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF IOWA, THE | $242,928 | Trans-NIH Recovery Act Research Support Production of reactive oxygen species (ROS) and changes in the cellular redox environment regulate various aspects of cellular function. Previous studies of oxidative stress in vascular disease have focused on ROS generating systems. Little is known, ho | National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF IOWA, THE | $235,649 | Trans-NIH Recovery Act Research Support HIV disease progression varies widely among individuals. Although some genetic or HIV protein factors have been identified that affect disease progression, these do not explain slow HIV disease progression in most cases. We and others found an association | National Institutes of Health | 4/19/2010 |
| UNIVERSITY OF IOWA, THE | $232,992 | Trans-NIH Recovery Act Research Support Intracranial aneurysms are abnormal dilations of brain arteries that may rupture in some patients causing stroke and possibly death. Some treatment modalities are available, but they carry risks to patient health and hence best performed only on aneurysms | National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF IOWA, THE | $232,622 | Trans-NIH Recovery Act Research Support Cardiac arrhythmias are the leading cause of death among heart failure (HF) patients. A growing body of evidence indicates that dysregulation in intracellular Ca2+ is a critical factor in these arrhythmias. Importantly, alterations in myocyte Ca2+ release | National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF IOWA, THE | $229,644 | Trans-NIH Recovery Act Research Support Role of syntaxin 6 regulated post-Golgi trafficking in angiogenesis refers to the establishment of new vessels from preexisting vasculature. Dysfunctions in angiogenesis can lead to several malignant, inflammatory, and ischemic disorders. New vessel forma | National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF IOWA, THE | $225,000 | Refactoring the ITK FEM Framework | National Institutes of Health | 6/21/2010 |
| UNIVERSITY OF IOWA, THE | $225,000 | Trans-NIH Recovery Act Research Support Refactoring the ITK FEM Framework | National Institutes of Health | 6/21/2010 |
| UNIVERSITY OF IOWA, THE | $225,000 | Refactoring the ITK FEM Framework | National Institutes of Health | 6/21/2010 |
| UNIVERSITY OF IOWA, THE | $224,228 |
Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (15): 15-NS-102: Translation of Gene Silencing Therapeutics. The proposed challenge set forth in the RFA is to extend the current understanding of the feasibility and safety of RNA interference (RNAi) therap
This spending item is part of a $933,051 allocation.
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National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF IOWA, THE | $220,234 | Trans-NIH Recovery Act Research Support A. Purpose and Functions The Institute for Clinical and Translational Research will train highly motivated clinical research scholars for innovative careers in patient-focused research. The training programs will provide a comprehensive curriculum across | National Institutes of Health | 8/05/2010 |
| UNIVERSITY OF IOWA, THE | $216,051 | Trans-NIH Recovery Act Research Support Intervertebral total disc replacement (TDR) implants potentially herald a paradigm shift in the management of degenerative disc disease. Preservation of motion may avoid adjacent-segment degeneration, a well- recognized complication of fusion. Based on en | National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF IOWA, THE | $207,560 | Trans-NIH Recovery Act Research Support Abstract RGS (Regulator of G protein Signaling) proteins represent a novel protein family believed to function as GTPase-activating proteins (GAPs) for heterotrimeric G protein subunits, thereby negatively regulating the duration and intensity of G prote | National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF IOWA, THE | $207,481 | Trans-NIH Recovery Act Research Support Acetylcholinesterase inhibiting pesticides (i.e., organophosphate (OP) and carbamate pesticides) are widely used in the US and worldwide. Long-term neurological and neurobehavioral health effects of exposure to these pesticides are not well characterized. | National Institutes of Health | 8/15/2009 |
| UNIVERSITY OF IOWA, THE | $205,020 | Trans-NIH Recovery Act Research Support The goal of this training program is to train biostatisticians to take a leadership role in developing new interdisciplinary scientific research. This will be achieved by providing rigorous training in the disciplines of statistics and microbiology, and a | National Institutes of Health | 8/03/2009 |
| UNIVERSITY OF IOWA, THE | $203,400 | Trans-NIH Recovery Act Research Support The proposal is a response to Notice Number (NOT-OD-10-032) and Notice Title: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications (R01, R03, R15, R21, R21/R33, and R37) through the NIH Basic Behavioral and Social Sci | National Institutes of Health | 9/25/2010 |
| UNIVERSITY OF IOWA, THE | $201,794 |
Trans-NIH Recovery Act Research Support This application is in response to Challenge Area 04-HL-104, 'Perform secondary analyses of existing data to answer important clinical and preventive medicine research questions.' The specific topic is #8, 'Analysis of genetic markers related to risk fact
This spending item is part of a $970,456 allocation.
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National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF IOWA, THE | $200,683 | Trans-NIH Recovery Act Research Support The long-term goal of our research is to understand the replication of damaged DNA in eukaryotes at the thermodynamic, kinetic, and structural levels. DNA damage in the template strand blocks replication by classical DNA polymerases. Consequently cells po | National Institutes of Health | 9/09/2009 |
| UNIVERSITY OF IOWA, THE | $200,000 | Trans-NIH Recovery Act Research Support Funds are requested to upgrade the ultrasound imaging capabilities of The Cardiovascular Phenotype Core at the University of Iowa. The Core was founded with NIH support in 2002, and has completed over 9,000 research ultrasound imaging studies in rodents w | National Institutes of Health | 1/28/2010 |
| UNIVERSITY OF IOWA, THE | $198,000 | Trans-NIH Recovery Act Research Support Despite years of research and a considerable monetary expenditure the pathophysiology of the Urologic Chronic Pelvic Pain Syndrome (UCPPS) known as Interstitial Cystitis/Painful Bladder Syndrome (IC/PBS) remains elusive. This University of Iowa MAPP grant | National Institutes of Health | 9/27/2009 |
| UNIVERSITY OF IOWA, THE | $182,679 | Trans-NIH Recovery Act Research Support Approximately 6 million people in the United States suffer from chronic angina, a painful sensation resulting from myocardial ischemia in the setting of coronary artery disease. Ischemia is sensed by sensory (afferent) neurons, and activation of these car | National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF IOWA, THE | $182,190 | Trans-NIH Recovery Act Research Support The long-term goal of this proposal is to understand the molecular mechanisms that regulate exocytosis in order to comprehend and develop therapies for devastating human diseases in which exocytosis is defective, such as diabetes and polycystic kidney dis | National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF IOWA, THE | $172,711 | Trans-NIH Recovery Act Research Support Cocaine addiction is a serious problem afflicting the United States, and treatment remains imperfect. Although the study of cocaine self-administration and reinstatement in rats has provided much knowledge of cocaine addiction, relatively few studies have | National Institutes of Health | 7/10/2010 |
| University of Iowa, The (inc) | $170,000 |
The purpose of this statement of work is to inform the CMS Strategic Plan by: (1) Conducting an environmental scan of all existing CMS data resources and reporting services that may be used by external end-users for Comparative Effectiveness Research (CER
This spending item is part of a $496,510 allocation.
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Health Care Financing Admin. (was Medicare and Medicaid Serv.) | 8/03/2010 |
| UNIVERSITY OF IOWA, THE | $169,660 |
ARRA ?Health Information Technology and Public Health The Iowa Department of Public Health, in collaboration with the University Hygienic Laboratory (UHL), IowaG??s state public health laboratory, intends to use the ELC Infrastructure and Interoperability Support for Public Health Laboratories (fundiding oppor... Show more
This spending item is part of a $578,833 allocation.
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Centers for Disease Control and Prevention | 8/02/2010 |
| UNIVERSITY OF IOWA, THE | $160,845 |
Trans-NIH Recovery Act Research Support In 2008, over 66,000 people in the US will be diagnosed with Non-Hodgkin lymphoma (NHL), and over 19,000 will die of this cancer. Survival rates have only recently begun to improve, and the current 5-year survival rate is 66%. We have identified a number
This spending item is part of a $1,230,557 allocation.
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National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF IOWA, THE | $157,600 |
Trans-NIH Recovery Act Research Support This supplement is the NORDIC (Neuro-Ophthalmology Research Disease Investigator Consortium) Headquarters portion of a joint effort for both Drs Mark Kupersmith and Karl Kieburtz on behalf of our respective institutions, St. Luke?s Roosevelt Hospital and
This spending item is part of a $799,913 allocation.
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National Institutes of Health | 8/19/2009 |
| UNIVERSITY OF IOWA, THE | $150,000 | Trans-NIH Recovery Act Research Support Group B Streptococci (GBS) has emerged as one of the most important infectious causes of neonatal morbidity and mortality and pregnancy-related morbidity. A GBS infection in the pregnant patient places the mother and child at high risk for complications. | National Institutes of Health | 5/11/2009 |
| UNIVERSITY OF IOWA, THE | $143,776 | Trans-NIH Recovery Act Research Support Mitochondria provide energy, buffer calcium, and sequester cell death-inducing molecules, and mitochondrial dysfunction is implicated in various neuropathologies. Especially in neurons, mitochondria are highly dynamic organelles that constantly move, divi | National Institutes of Health | 8/11/2009 |
| UNIVERSITY OF IOWA, THE | $143,570 | Trans-NIH Recovery Act Research Support This study will evaluate 5-year outcomes in patients with head and neck cancer (HNC) using the Outcomes Assessment Study (OAS), a project initiated in 1995 at the University of Iowa to collect health related quality of life (HRQOL) data in this understudi | National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF IOWA, THE | $141,814 | ARRA - Scholarships for Disadvantaged Students ARRA - Scholarships for Disadvantaged Students: as indicated by the award title, the funds of this award are to provide scholarships for disadvantaged students. Eligible students will be identified to receive the scholarship funds. | Health Resources and Services Administration | 6/14/2010 |
| UNIVERSITY OF IOWA, THE | $141,647 | Trans-NIH Recovery Act Research Support Voltage-gated Nav channel Nav1.5 (encoded by SCN5A) initiates rapid depolarization of the cardiac action potential and is essential for normal cardiac conduction. Human SCN5A mutations may lead to cardiac arrhythmia and sudden death. Nav1.5 function is de | National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF IOWA, THE | $137,028 |
Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Varicella zoster virus (VZV) causes varicella during primary infection, persists in sensory ganglia and may reactivate from latency to cause zoster. VZV pathogenesis depends upon its tropisms for T cells, skin and sens
This spending item is part of a $981,556 allocation.
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National Institutes of Health | 6/18/2009 |
| UNIVERSITY OF IOWA, THE | $130,731 | Trans-NIH Recovery Act Research Support Effective systemic treatments for diseases of the central nervous system require therapeutic agents that are able to cross the blood-brain barrier (BBB). Significant efforts are devoted to design drug molecules with the correct permeability characteristic | National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF IOWA, THE | $128,861 | Trans-NIH Recovery Act Research Support Speech perception is a process of mapping continuous detail in the acoustic signal onto discrete units of meaning like words. Given the variability in the signal and speed at which it arrives, the system must cope with a great deal of variation in a small | National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF IOWA, THE | $128,627 |
Trans-NIH Recovery Act Research Support Accumulation of pathogenic proteins and peptides with expanded polyglutamine repeats is characteristic of Huntington's disease (HD) and related neurodegenerative diseases, however precise molecular mechanisms that underlie pathogenesis remain elusive. Be
This spending item is part of a $277,387 allocation.
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National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF IOWA, THE | $128,452 |
Trans-NIH Recovery Act Research Support While previous studies have shown that children with mild-to-severe hearing loss are at risk for poorer language, academic, social and psychological outcomes, these studies were conducted prior to the implementation of universal newborn hearing screening
This spending item is part of a $470,431 allocation.
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National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF IOWA, THE | $107,950 | Trans-NIH Recovery Act Research Support This K07 Career Development Award application is designed to expand my career development from cancer etiology to cancer prevention and control. The career development plan rests on mentoring directed by experts in cancer prevention research and 'protecte | National Institutes of Health | 9/14/2009 |
| UNIVERSITY OF IOWA, THE | $107,853 | Trans-NIH Recovery Act Research Support The final resubmission of a Mentored Patient-Oriented Career Development Award Application (K23) to support Dr. Lisa Segre's development as an academic research scientist with expertise in the development of perinatal depression treatments for low-income | National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF IOWA, THE | $104,674 | Trans-NIH Recovery Act Research Support Extending from the surface of nearly all of the cells in our body is a primary cilium, which is thought to function as an antenna monitoring environmental conditions and to be crucial for the maintenance of normal cell behavior. Primary cilia have attract | National Institutes of Health | 8/30/2010 |
| UNIVERSITY OF IOWA, THE | $103,621 |
Trans-NIH Recovery Act Research Support For over 40 years, the U.S. military has recognized that the toxin SEB (staphylococcal enterotoxin B) poses a serious incapacitating and lethal threat. In the past 15 years, various biochemical and molecular studies have shown that SEB acts as a superanti
This spending item is part of a $639,651 allocation.
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National Institutes of Health | 8/02/2010 |
| UNIVERSITY OF IOWA, THE | $102,079 | Trans-NIH Recovery Act Research Support In addition to their bioenergetic function, mitochondria are critical regulators of Ca signaling in neurons. Mitochondria efficiently buffer Ca2+ influx during excitation and limit the amplitude of the cytosolic Ca2+ concentration ([Ca2+]i) increase. Rapi | National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF IOWA, THE | $100,651 | Trans-NIH Recovery Act Research Support Genetic pathways that promote cell-survival during development are poorly defined, yet represent potential targets for anti-cancer drugs. The genes that promote survival of melanocytes, in particular those that operate independently of the well-characteri | National Institutes of Health | 1/08/2010 |
| UNIVERSITY OF IOWA, THE | $100,001 | Trans-NIH Recovery Act Research Support Gallstone pancreatitis is common and is potentially fatal. Enteral exclusion of bile-pancreatic juice by the stone causes feedback hyperstimulation of the exocrine pancreas that induces pancreatic overproduction of acute inflammatory mediators. Systemic s | National Institutes of Health | 9/04/2009 |
| INTEGRATED DNA TECHNOLOGIES INC | $99,750 | Trans-NIH Recovery Act Research Support The National Institutes of Health awarded IDT a Phase 1 SBIR grant (GM085863-01) effective Aug 15, 2008. The project relates to development of U1 Adaptors, a new class of synthetic nucleic acids that are capable of specific down regulation of gene expres | National Institutes of Health | 8/17/2009 |
| UNIVERSITY OF IOWA, THE | $99,348 | Trans-NIH Recovery Act Research Support Calcitonin gene-related peptide (CGRP) has been implicated in craniofacial pain and headache by virtue of its expression in the trigeminal ganglion and roles in neurogenic inflammation and nociception. In particular, CGRP levels are elevated in migraine, | National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF IOWA, THE | $98,880 | Trans-NIH Recovery Act Research Support The long-term objectives and specific aims of this proposal are to establish the University of Iowa Department of Urology and Preventive Medicine trials group as a Clinical Evaluation and Treatment Center (CETC) in a multi-institutional research consortiu | National Institutes of Health | 9/30/2010 |
| UNIVERSITY OF IOWA, THE | $98,028 | Trans-NIH Recovery Act Research Support We have discovered 2 ubiquitin sorting receptors (Ub-sorting receptors) that sort ubiquitinated membrane proteins (Ub-cargo) for degradation in the lysosome. One is the GGA coat protein, which appears to bind Ubcargo at the TGN and incorporate it into ves | National Institutes of Health | 2/17/2010 |
| UNIVERSITY OF IOWA, THE | $91,575 |
Trans-NIH Recovery Act Research Support Postoperative pain remains a significant problem in up to 30% of postoperative patients. Pain due to related types of inflammatory lesions and trauma affects a large number of additional individuals. Understanding the mediators present near incisional w
This spending item is part of a $230,290 allocation.
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National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF IOWA, THE | $86,945 | Trans-NIH Recovery Act Research Support Over the last decade, the prescribing rate of atypical antipsychotics (AAPs) for youth has increased by several folds. This has resulted in a striking contrast between the use of AAPs and the limited scientific evidence regarding their efficacy and safety | National Institutes of Health | 3/15/2010 |
| UNIVERSITY OF IOWA, THE | $84,375 | Trans-NIH Recovery Act Research Support Multidrug resistance often arises in human tumors due to overexpression of plasma membrane ATP-binding cassette (ABC) transporter proteins. Recent experiments have indicated that multidrug resistant cells frequently exhibit changes in the profile of lipid | National Institutes of Health | 3/17/2010 |
| UNIVERSITY OF IOWA, THE | $78,950 |
Trans-NIH Recovery Act Research Support This project will utilize high-throughput genetic technologies in a major longitudinal behavioral study and renew the biomedical research community by building scientific partnerships for the integration of behavioral and genetic science. The 7,000 indivi
This spending item is part of a $5,683,130 allocation.
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National Institutes of Health | 9/21/2010 |
| UNIVERSITY OF IOWA, THE | $77,597 |
Trans-NIH Recovery Act Research Support The proposed study can make more efficient use of cancer genomic data by properly accounting for the clustering structure of gene expressions and selecting predictive cancer biomarkers. It can provide more insights into the genomic mechanisms of cancer oc
This spending item is part of a $173,605 allocation.
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National Institutes of Health | 7/22/2009 |
| UNIVERSITY OF IOWA, THE | $77,425 |
Trans-NIH Recovery Act Research Support Role of microRNAs in mammalian ear development and neurosensory specification The purpose of this biomedical basic research grant is to investigate the function of genetic regulatory molecules termed microRNAs in the development and maintenance of sensor
This spending item is part of a $694,185 allocation.
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National Institutes of Health | 6/02/2009 |
| UNIVERSITY OF IOWA, THE | $76,088 |
Trans-NIH Recovery Act Research Support Here we investigate a novel antimicrobial approach using the metal gallium (Ga) as a 'Trojan horse' to disrupt bacterial Fe metabolism. Ga has a nearly identical ionic radius as Fe, and many biologic systems are unable to distinguish Ga from Fe. Ga disr
This spending item is part of a $907,417 allocation.
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National Institutes of Health | 5/30/2009 |
| UNIVERSITY OF IOWA, THE | $75,805 |
Trans-NIH Recovery Act Research Support Congenital defects remain the greatest contributor to infant mortality; yet, the causes for the majority of these defects are either unknown or poorly understood. Amine- and amide-containing (nitrosatable) drugs and other compounds react with nitrite in t
This spending item is part of a $281,342 allocation.
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National Institutes of Health | 9/06/2009 |
| UNIVERSITY OF IOWA, THE | $75,794 |
Trans-NIH Recovery Act Research Support Sexual reproduction is prevalent in eukaryotes and plays a key role in their fitness and survival. Asexual species often arise, but regularly go extinct due, in part, to deleterious mutation accumulation and the inability to adapt to changing environments
This spending item is part of a $120,763 allocation.
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National Institutes of Health | 1/08/2010 |
| UNIVERSITY OF IOWA, THE | $75,084 | Trans-NIH Recovery Act Research Support Negative reinforcement (i.e., escape from or avoidance of instructions) has been identified as one of the leading variables responsible for the maintenance of destructive behavior exhibited by individuals with developmental disabilities. Several treatment | National Institutes of Health | 9/07/2010 |
| UNIVERSITY OF IOWA, THE | $63,964 | Trans-NIH Recovery Act Research Support The principal goal of this training grant (TG) is to promote the interdisciplinary training of graduate students in Pharmacological Sciences. Its secondary goal is to foster interactions among faculty and students from different Departments that share an | National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF IOWA, THE | $60,000 | Trans-NIH Recovery Act Research Support The long-term goal of these studies is to better understand cell division in the model organism Escherichia coli. A deeper understanding of bacterial cell division is expected to facilitate the development of new antibiotics and will therefore benefit pub | National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF IOWA, THE | $60,000 | Trans-NIH Recovery Act Research Support It has become apparent that RNA polymerase II (RNAPII) elongation control plays a major role in regulating transcription throughout development and differentiation of multi-cellular organisms. The process is characterized by the default action of negative | National Institutes of Health | 8/13/2010 |
| UNIVERSITY OF IOWA, THE | $58,756 |
Trans-NIH Recovery Act Research Support PREDICT-HD is an international 30-site observational study of persons at-risk for Huntington's disease (HD). PREDICT-HD capitalizes on two unique aspects of HD among neurodegenerative disorders the ability to know in advance who will develop the disease a
This spending item is part of a $582,540 allocation.
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National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF IOWA, THE | $54,082 | Trans-NIH Recovery Act Research Support The long-term goal of this research program is to elucidate the molecular mechanisms of the function and regulation of rod and cone cGMP-phosphodiesterases (PDE6). PDE6s serve as key effector enzymes in the vertebrate visual transduction cascade. Transduc | National Institutes of Health | 9/02/2009 |
| UNIVERSITY OF IOWA, THE | $54,000 | Trans-NIH Recovery Act Research Support The Pax2 gene is an essential regulator of early renal development and has also been implicated in a variety of human diseases both congenital and acquired. During embryonic development, Pax2 is required for the initiation and maintenance of the conversio | National Institutes of Health | 12/17/2009 |
| UNIVERSITY OF IOWA, THE | $51,710 | Trans-NIH Recovery Act Research Support Infection of humans with Plasmodium species, the parasites that cause malaria, remains a significant global health problem. There are approximately 300-500 million new cases of malaria each year, which results in the death of 1-3 million people annually. | National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF IOWA, THE | $51,511 |
Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): When environmental exposure assessment studies provide feedback to the lay public, the resultant communications generally focus on the exposure assessment itself (e.g., serum levels) and not the relationship of the exp
This spending item is part of a $771,736 allocation.
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National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF IOWA, THE | $50,000 | Trans-NIH Recovery Act Research Support In this K01 application, Philip Polgreen, MD, seeks to gain expertise in graph theory pertaining to social networks and in mathematical simulations for developing more effective interventions to minimize the spread of nosocomial infections (specifically i | National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF IOWA, THE | $50,000 | Trans-NIH Recovery Act Research Support This application is to provide support for a supervised research career development experience for Dr. David Stoltz in the field of airway cell biology. Dr. Stoltz has completed a combined M.D./Ph.D. program and is currently in the Pulmonary/Critical Care | National Institutes of Health | 9/11/2009 |
| UNIVERSITY OF IOWA, THE | $50,000 | Trans-NIH Recovery Act Research Support In this K01 application, Philip Polgreen, MD, seeks to gain expertise in graph theory pertaining to social networks and in mathematical simulations for developing more effective interventions to minimize the spread of nosocomial infections (specifically i | National Institutes of Health | 8/02/2010 |
| UNIVERSITY OF IOWA, THE | $50,000 | Trans-NIH Recovery Act Research Support This application is to provide support for a supervised research career development experience for Dr. David Stoltz in the field of airway cell biology. Dr. Stoltz has completed a combined M.D./Ph.D. program and is currently in the Pulmonary/Critical Care | National Institutes of Health | 8/02/2010 |
| UNIVERSITY OF IOWA, THE | $49,272 | Trans-NIH Recovery Act Research Support The University of Iowa Holden Comprehensive Cancer Center (HCCC), a matrix cancer center at the University of Iowa, is applying for renewal of its Cancer Center Support grant. This is the first competitive renewal application for the HCCC. The Cancer Cent | National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF IOWA, THE | $44,714 |
Trans-NIH Recovery Act Research Support We plan a multi-center study to accurately describe the natural history of late kidney transplant failure, and to dissect out individual entities leading to late deterioration of function and to graft loss. Previous studies, and the current literature, at
This spending item is part of a $1,128,568 allocation.
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National Institutes of Health | 6/28/2010 |
| UNIVERSITY OF IOWA, THE | $42,250 | ARRA - Scholarships for Disadvantaged Students Scholarships for Disadvantaged Students in Allopathic Medicine | Health Resources and Services Administration | 9/03/2009 |
| UNIVERSITY OF IOWA, THE | $41,872 | Trans-NIH Recovery Act Research Support This project continues the University of Iowa's multi-level International Training and Research Program in Occupational and Environmental Health (ITREOH) in an expanded number of developing democracies in Central and Eastern Europe. This program will buil | National Institutes of Health | 9/03/2009 |
| UNIVERSITY OF IOWA, THE | $38,962 | Trans-NIH Recovery Act Research Support Respiratory syncytial virus (RSV) is the leading cause of viral lower respiratory tract infection in infants and young children. In addition, RSV causes serious disease in elderly and immune compromised individuals. Immunization against RSV is associated | National Institutes of Health | 8/11/2009 |
| UNIVERSITY OF IOWA, THE | $35,664 | Trans-NIH Recovery Act Research Support This award is issued in response to Notice OD-09-060, Recovery Act Administrative Supplements Providing Summer Research Experiences for Students and Science Educators. This research application is in response to #RFA-DA-06-004. At the heart of drug and al | National Institutes of Health | 6/01/2009 |
| UNIVERSITY OF IOWA, THE | $34,548 |
Trans-NIH Recovery Act Research Support The impact that drug addictions have on health disparities impacting at-risk African Americans who reside in the rural South are grossly understudied. While there is strong evidence linking drug use and abuse to violent behaviors, injuries, mental health,
This spending item is part of a $471,683 allocation.
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National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF IOWA, THE | $33,300 |
Trans-NIH Recovery Act Research Support The overarching goal of the Function BIRN (FBIRN) is to develop technology and methods to conduct multi- site functional imaging studies, and to produce a knowledge base that would not otherwise be available through single-site imaging studies. The techno
This spending item is part of a $926,175 allocation.
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National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF IOWA, THE | $32,910 | ARRA ? Equipment to Enhance Training for Health Professionals Equipment to Enhance Training for Health Professionals - Funds were awarded to purchase equipment to enhance the oral health care of wheelchair-bound and homebound patients and enhance senior dental extramural training on the Geriatric Mobobile Unit.... Show more | Health Resources and Services Administration | 9/04/2010 |
| UNIVERSITY OF IOWA, THE | $31,653 | Trans-NIH Recovery Act Research Support The goal of this proposal is to understand the role of the Sen1 helicase in termination of RNA Polymerase II (PolII) transcripts and to establish how mutations in the human homolog of Sen1, Senataxin (SETX), cause the neurodegenerative disorders Ataxia-Oc | National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF IOWA, THE | $31,268 | Trans-NIH Recovery Act Research Support Multidrug resistance is an important clinical impediment in the use of chemotherapies of all types. We are using the yeast Saccharomyces cerevisiae as a model eukaryotic system that has a well described set of multidrug resistance loci called pleiotropic | National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF IOWA, THE | $22,140 |
Trans-NIH Recovery Act Research Support Dr. Mariam Aziz - During the past year, we have continued our studies looking at HIV specific ADCC activity in the genital mucosa women in two unique populations of women; women who seroconverted to HIV and women who are at high risk because they regularl
This spending item is part of a $279,804 allocation.
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National Institutes of Health | 8/23/2010 |
| UNIVERSITY OF IOWA, THE | $18,538 |
Trans-NIH Recovery Act Research Support A critical issue for disaster response is group or collaborative computing in mobile environments. This application describes research to address three critical inter-related problems that inhibit the successful use of information technologies at disaster
This spending item is part of a $3,157,848 allocation.
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National Institutes of Health | 9/17/2009 |