Washtenaw County, Mich., funds by Health and Human Services, Department of
Listing $217,591,325.79 in stimulus funds from Health and Human Services, Department of for Washtenaw
Note: For some programs where states do not report where money will be distributed across the state, we do not have the allocation for individual counties. Those programs include: Medicaid, unemployment benefits and food stamps. Those amounts are included in the totals for where the state agency receiving that money is located.
Amount refers to both the amount of stimulus funding going toward the project and the face value of the loan.
| Recipient | Amount | Description | Federal Dept./Agency | Date |
|---|---|---|---|---|
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $14,824,023 | National Center for Research Resources, Recovery Act Construction Support In recognition of the critical role that social, psychological, and lifestyle factors (social determinants of health) play in disease onset, progression, and amelioration, the NIH over the last two decades has supported an incrcreasing portfolio of extramur... Show more | National Institutes of Health | 2/25/2010 |
| ALTARUM INSTITUTE | $10,566,757 |
ARRA - Health Information Technology Extension Program MCEITA has a mision to provide technical assistance to improve the quality and value of health care delivery in our state. Our overarching goal is to systematically improve population health and ensure the delivery of well-coordinated, high qualality care.... Show more
This spending item is part of a $21,052,308 allocation.
See details
|
Health and Human Services, Department of | 2/08/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $7,877,079 |
Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): This revision application (formerly called competing supplement) to the Health and Retirement Study (NLA U01AG009740) proposes to collect and distribute the first repeat longitudinal wave of biomarker and psychosocial
This spending item is part of a $8,032,621 allocation.
See details
|
National Institutes of Health | 8/14/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $6,652,481 |
Trans-NIH Recovery Act Research Support A Grand Opportunity for scientific advance has been created by the confluence of falling costs of genotyping, the development of statistical methods for genome-wide association studies (GWAS), and the creation of a substantial repository of genetic materi
This spending item is part of a $6,741,000 allocation.
See details
|
National Institutes of Health | 9/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $5,750,000 |
Trans-NIH Recovery Act Research Support This ARRA supplement under the parent U01 grant was funded to expand the original parent U01 scope of work. Based on our earlier meetings with NIMH and the US Army, the focus of this study was expanded in five ways: (i) the range of outcomes assessed; (i
This spending item is part of a $10,000,000 allocation.
See details
|
National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $5,454,781 |
Trans-NIH Recovery Act Research Support This project will utilize high-throughput genetic technologies in a major longitudinal behavioral study and renew the biomedical research community by building scientific partnerships for the integration of behavioral and genetic science. The 7,000 indivi
This spending item is part of a $5,683,130 allocation.
See details
|
National Institutes of Health | 9/21/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $4,138,078 |
Trans-NIH Recovery Act Research Support Grant name: POINT. The purpose of the Platelet-Oriented Inhibition in New TIA and minor ischemic stroke (POINT) Trial is to determine the safety and effectiveness of the combination of low-dose aspirin and a medication called clopidogrel (also known by th
This spending item is part of a $12,424,539 allocation.
See details
|
National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $3,990,588 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): This application responds to NHGRI's call for Medical Sequencing Discovery Projects that will use next-generation sequencing technology to tackle high-impact challenges in medical genetics. We propose to build on our s | National Institutes of Health | 9/30/2009 |
| MATHEMATICA POLICY RESEARCH, INC. | $3,420,889 |
The purpose of this task order award is to conduct the study entitled 'Global Assessment of the Value of Health Information Technology and Office of the National Coordinator for Health Information Technology Programs.' The awardee, Mathematica Policy Rese
This spending item is part of a $3,985,751 allocation.
See details
|
Program Support Center | 3/26/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $3,342,419 | Trans-NIH Recovery Act Research Support This is competing continuation proposal for Years 17-22 of the Health and Retirement Study (HRS). We propose to continue core data collection on the steady-state design laid out in the previous renewal, including the addition of a new cohort in 2010; to b | National Institutes of Health | 9/24/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $3,085,193 |
Trans-NIH Recovery Act Research Support Patient recruitment and retention Patient recruitment and retention of study subjects has been excellent in this study. The COMET Network was able to screen 108 potential subjects. From these there were 12 screen fails, 3 subjects withdrew consent, two
This spending item is part of a $7,915,507 allocation.
See details
|
National Institutes of Health | 9/28/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $2,400,000 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Pelvic floor disorders, such as urinary incontinence, pelvic organ prolapse, and fecal incontinence, are common and significant health-related problems for women in the United States. Outcomes following surgical and no | National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $2,317,500 | Trans-NIH Recovery Act Research Support DESCRIPTION (Provided by the applicant) Abstract: HIV/AIDS is one of the most destructive pandemics in human history, responsible for more than 25 million deaths. More than 30 million people live with limited or no access to therapeutic treatments, mainly | National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $1,431,093 |
Trans-NIH Recovery Act Research Support DESCRIPTION (provided by principal investigator): Preterm birth is a leading cause of infant mortality and morbidity in the U.S. and across the globe. Infection has consistently been identified as an important risk factor for preterm birth. A two to three
This spending item is part of a $1,531,170 allocation.
See details
|
National Institutes of Health | 9/14/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $1,396,894 | Trans-NIH Recovery Act Research Support The proposed Revision aims to contribute to the elimination of racial, ethnic and socioeconomic disparities in cardiovascular disease (CVD), including hypertension and stroke, the leading cause of death for all Americans, a major contributor to racial dis | National Institutes of Health | 9/23/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $1,393,524 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Since the completion of the Human Genome Project, there has been a rapid expansion in genetic technologies aimed at understanding complex human diseases, including high-density SNP genotyping for case-control and popul | National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $1,363,286 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The University of Michigan Comprehensive Cancer Center (UMCCC) requests renewal of its core grant in support of Senior Leadership, Programs, and Shared Core Facilities. A core grant to support the UMCCC was initially a | National Institutes of Health | 9/22/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $1,324,730 | Trans-NIH Recovery Act Research Support Purchase of a 700MHz NMR Spectrometer for Liquid Applications Project Summary Solution nuclear magnetic resonance (NMR) spectroscopy is one of the most powerful spectroscopic tools available to the synthetic chemist for the elucidation of the structure of | National Institutes of Health | 5/14/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $1,307,921 |
Recovery Act Comparative Effectiveness Research - AHRQ Pharmacological therapy is a critical component of diabetes treatment. Successful medications management requires a partnership between providers who initiate and titrate medications and patients who adhere to the regimen. Yet, there are high ratates both o... Show more
This spending item is part of a $1,480,432 allocation.
See details
|
Agency for Healthcare Research and Quality | 9/28/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $1,200,483 | Trans-NIH Recovery Act Research Support This application requests funds to purchase a Leica SP5X 2-photon laser-scanning confocal microscope system for the University of Michigan campus in Ann Arbor, Michigan. Currently there is no 2-photon confocal microscope system for shared use at the Univ | National Institutes of Health | 5/06/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $1,180,788 | Trans-NIH Recovery Act Research Support Identify all Meckel-like ciliopathy genes by exon capture & large-scale sequencing. Identification of mutations in proteins of the primary cilia-centrosome complex (CCC) defined the disease group of 'retinal-renal ciliopathies', the most frequent genetic | National Institutes of Health | 9/29/2010 |
| TRINITY HEALTH CORPORATION | $1,177,861 |
NCI's Community Cancer Centers Program (NCCCP) - The network of community hospitals is a complex pilot program whose mission is, through research, to determine ways to bring state of the art cancer care and clinical trials to patients in their local comm
This spending item is part of a $75,135,000 allocation.
See details
|
National Institutes of Health | 9/04/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $1,078,635 | Trans-NIH Recovery Act Research Support Oligomers formed by the amyloid beta peptide, A-beta, have been shown to be neurotoxic, can permeabilize biological membranes and are believed to be critical players in Alzheimer's disease (AD). Applying traditional approaches to study these oligomers and | National Institutes of Health | 9/11/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $1,075,349 | Trans-NIH Recovery Act Research Support The treatment of oncogenic lesions residing in bone has advanced with an ever increasing array of therapies; however, response to treatment is considered unmeasurable according to existing clinical response criteria (RECIST). Therefore, the biomarkers ava | National Institutes of Health | 5/21/2009 |
| THOMSON REUTERS (HEALTHCARE) INC. | $1,055,334 |
ARRA - HORIZON SCANNING SYSTEM - The purpose of this contract is to establish a system to conduct horizon scanning of healthcare technology in order to better inform comparative effectiveness research investments at the AHRQ through the Effective Healthca
This spending item is part of a $9,499,986 allocation.
See details
|
Agency for Healthcare Research and Quality | 9/01/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $1,050,000 |
Trans-NIH Recovery Act Research Support We are embarking on contributing to a large catalogue of DNA sequence variation in phenotyped samples and to pioneering the application of this depth and scale of data to the analysis of key cardiovascular phenotypes. We propose to do this by (1) performi
This spending item is part of a $24,870,017 allocation.
See details
|
National Institutes of Health | 9/28/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $1,037,831 |
Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): To enhance participant recruitment efforts for genetics studies and other large- scale etiological research efforts, there is a need for an instrument that can be practically and efficiently employed in research studie
This spending item is part of a $1,282,149 allocation.
See details
|
National Institutes of Health | 9/28/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $1,027,698 | Trans-NIH Recovery Act Research Support Literature and Data Driven Hypothesis Generation for High Throughput Experiments Microarray gene expression analyses are used widely in biomedical research today. Thousands of genes can be assayed in a single experiment, and differences in their expressio | National Institutes of Health | 5/07/2009 |
| EASTERN MICHIGAN UNIVERSITY | $1,000,000 | ARRA Strengthening Communities Fund This award is made to organizations with experience in capacity building and requires that they act as a lead organization for the project in a geographic service area which is at or below poverty level. Under this award, lead grantees select nonprofit or | Administration for Children and Families | 9/21/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $999,852 | Recovery Act Comparative Effectiveness Research - AHRQ The goal of this project is to develop a unique database linking clinical data from an electronic medical record (EMR) of a large academic healthcare system to multi-payer claims data. The population of patients will be all patients attributed toto a large ... Show more | Agency for Healthcare Research and Quality | 8/12/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $998,813 | Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (15) Translational Science and specific Challenge Topic, 15-HL-104: Characterize the role and effects of the respiratory and/or intestinal microbiota on the presence and clinical phenotype of lung disease. T | National Institutes of Health | 9/18/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $998,697 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): There is extensive research evidence that stressors in the social and physical environment are associated with poor health outcomes, and that these conditions contribute to ethnic, racial and socioeconomic health dispa | National Institutes of Health | 7/06/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $998,345 | Trans-NIH Recovery Act Research Support Endocrine disrupting compounds (EDCs) are hormonally active, synthetic or natural chemicals that interfere with normal functioning of the endocrine system. Exposure to EDCs continues to be a significant and contentious public health issue. Because of the | National Institutes of Health | 9/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $997,628 | Trans-NIH Recovery Act Research Support This application addresses broad Challenge area (15) Translational Science and specific Challenge Topic, 15-CA-101: The Role of Cellular Architecture in Normal and Tumor Cell Biology. New blood vessels are formed throughout life by either vasculogenic or | National Institutes of Health | 9/21/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $997,605 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): This application addresses broad Challenge Area (13): Smart Biomaterials - Theranostics, and specific Challenge Topic, 13-NS-101: Developing novel biomaterials to interfaces with neural activity. Implantable neural int | National Institutes of Health | 9/21/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $996,672 | Trans-NIH Recovery Act Research Support This application addresses the broad Challenge Area (04) Clinical Research and the NIA specific Challenge Topic 04-AG-105: Development of experience-based measures of well-being. There is an interdisciplinary resurgence of interest in the correlates and c | National Institutes of Health | 9/24/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $992,987 | Trans-NIH Recovery Act Research Support Genotyping the NPF Biobank for Psoriasis Susceptibility Genes This application addresses broad Challenge Area (08) Genomics and Specific Challenge Area: 08-AR-101 Genotyping of Existing Cohorts in Rheumatic, Skin, and Musculoskeletal Diseases. Psoriasis i | National Institutes of Health | 9/28/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $990,163 | Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (10) Information Technology for Processing Health Care Data and specific Challenge Topic, 10-HD-102: Data Archiving and Dissemination. The sharp increase in the sophistication of social science data systems | National Institutes of Health | 9/28/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $989,593 | Trans-NIH Recovery Act Research Support This application is directed to Challenge Area 14, Stem cells, and Specific Challenge Topic 14- NS-101, Reverse engineering human neurological disease: generation of stem cells from control and patient populations. The recent development of induced plurip | National Institutes of Health | 9/21/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $985,501 | Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area, (08) Genomics and Specific Challenge Topic, 08-ES-106: The role of environmental exposure in copy number variation (CNV): 'Microscopic deletions and replications of the genome have attracted increasing atte | National Institutes of Health | 9/28/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $984,303 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The aim of this proposal is to develop novel, tailored agents than can induce the generation of human fetal red blood cells from adult hematopoietic stem cells by reprogramming -type globin gene regulation. Such agents | National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $981,458 | Trans-NIH Recovery Act Research Support Chronic kidney diseases take one of the highest tolls on human health. Steroid-resistant nephrotic syndrome (SRNS) is a rare disease that constitutes the second most frequent cause of ESKD in children and young adults. No curative treatment is available. | National Institutes of Health | 9/21/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $980,401 | Trans-NIH Recovery Act Research Support Challenge Area (11) Regenerative Medicine: 11-DK-101: Promote regeneration and repair in the digestive system, liver, pancreas, hematology, kidneys and urological system. Fecal incontinence is a condition with ramifications that extend well beyond the phy | National Institutes of Health | 9/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $974,463 | Trans-NIH Recovery Act Research Support The pituitary gland contains individualized cell types that specialize in the production of individual hormones. Understanding the mechanisms that underlie the transition from proliferation to cell differentiation is important because many body functions | National Institutes of Health | 9/15/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $971,456 | Trans-NIH Recovery Act Research Support The Use of Erythropoietin to Reprogram Oral and Craniofacial Stem Cells. This project directly addresses Challenge Area (14)-Stem Cells, specifically 14-DE-101* Reprogramming of Cells from Oral and Craniofacial Tissues in which we developed a novel approa | National Institutes of Health | 9/22/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $968,688 |
Trans-NIH Recovery Act Research Support This is a proposal to continue a unique microlevel study of the reciprocal relationships between population processes (marriage, fertility, and migration) and the environment (land usefcover, vegetation abundance and species diversity, and consumption of
This spending item is part of a $1,039,836 allocation.
See details
|
National Institutes of Health | 7/24/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $953,579 |
Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): This application addresses the broad Challenge Area (03) Biomarker Discovery and Validation and the specific Challenge Topic, 03-HL-101: Identify and validate clinically relevant, quantifiable biomarkers of diagnostic
This spending item is part of a $999,999 allocation.
See details
|
National Institutes of Health | 9/28/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $947,508 |
Trans-NIH Recovery Act Research Support Modular Software for Sequence Data Quality Checking Alignment and Variant Calling: The purpose of this project is to implement a DNA sequence processing pipeline at the National Center for Biotechnology Information (NCBI) at the NIH. This pipeline is inte
This spending item is part of a $2,249,700 allocation.
See details
|
National Institutes of Health | 9/21/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $942,329 |
Trans-NIH Recovery Act Research Support The hypothalamic-pituitary-adrenal (HPA) axis and its byproduct, cortisol, have been hypothesized to be the mediators that links chronic stress to adverse health outcomes, including increased obesity risk. This mediation is hypothesized to occur via sever
This spending item is part of a $997,523 allocation.
See details
|
National Institutes of Health | 9/28/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $939,608 | Trans-NIH Recovery Act Research Support This application requests funds to purchase an Olympus FV1000-MPE confocal and multi-photon fluorescence microscope imaging system dedicated to intravital microscopy in small animals. The intravital microscope system will be housed, managed, and maintaine | National Institutes of Health | 4/15/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $926,262 | Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (01) Behavior, Behavioral Change, and Prevention and specific Challenge Topic, 01-AA-103: Capturing Social Network Information for Groups at High Risk for Negative Health Behaviors. NIH has identified the In | National Institutes of Health | 9/21/2009 |
| COUNTY OF WASHTENAW | $925,193 |
ARRA - Community Services Block Grant The Community Services Block Grant Program has allocated funds to a network of eligible entities to support employment related services, which create and sustain economic growth. Ninety-nine percent of the funding was distributed to eligible entities to
This spending item is part of a $36,840,330 allocation.
See details
|
Administration for Children and Families | 4/10/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $898,474 |
Trans-NIH Recovery Act Research Support Challenge Area of Personalized Drug Response and Toxicity Challenge Topic: 04-GM-101 A. Specific aims It is well established that drug toxicity varied individually. Although some genetic loci have been identified, most of the genetic factors remain to be
This spending item is part of a $998,474 allocation.
See details
|
National Institutes of Health | 9/25/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $827,427 |
Trans-NIH Recovery Act Research Support Enhancing Community/Academic Clinical Research Collaboration From its inception, the Michigan Institute for Clinical and Health Research (MICHR) Community Engagement Program (CE) has based its efforts on the guiding principles of Community Based Participa
This spending item is part of a $997,227 allocation.
See details
|
National Institutes of Health | 8/19/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $813,566 | Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area of 'Information Technology for Processing Health Care Data' (Area # 10) and two specific Challenge topics (10-RR-101): Information Technology Demonstration Projects Facilitating Secondary Use of Healthcare D | National Institutes of Health | 9/24/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $809,819 |
Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (02) Bioethics and specific Challenge Topic, 02-HG-101: Informed consent and data access policies. The ethical, legal, and social issues (ELSI) underlying the development and implementation of state-sponsore
This spending item is part of a $899,991 allocation.
See details
|
National Institutes of Health | 9/25/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $800,000 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The Southwest Oncology Group is an adult, multi-disease, multi-modality clinical cancer research organization with 35 Member Institutions, 29 Community Clinical Oncology Program (CCOP) institutions, including 7 Minorit | National Institutes of Health | 8/12/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $793,843 |
Trans-NIH Recovery Act Research Support One fifth of America's children grow up in poverty. While there is good evidence that this is harmful to health, achievement, and socio-emotional adjustment, very little is known about the brain basis that mediates the detrimental effects of poverty. We a
This spending item is part of a $1,443,756 allocation.
See details
|
National Institutes of Health | 9/28/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $780,298 | Trans-NIH Recovery Act Research Support The purpose of this proposal is to recruit two faculty members to the Musculoskeletal Research Consortium program at the University of Michigan. The new faculty will be part of an innovative multidisciplinary program focused on the interface between tendo | National Institutes of Health | 9/25/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $769,776 | Trans-NIH Recovery Act Research Support Approximately 40,000 Americans are diagnosed with brain tumors each year, with15-35% being glioblastoma multiforme (GBM), an aggressive primary brain tumor that has defied all existing therapeutic modalities. Treatment of brain tumors normally begins with | National Institutes of Health | 9/20/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $763,360 | Trans-NIH Recovery Act Research Support This project makes publicly available via ICPSR an existing longitudinal individual-level database, the Liaoning Multi-Generational Panel (LMGP), that comprises 1.3 million triennial observations of more than 230,000 residents of approximately 628 northea | National Institutes of Health | 9/22/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $760,358 | Trans-NIH Recovery Act Research Support Extracellular secretion and targeted delivery by the type II secretion (T2S) system is considered a major virulence mechanism in gram negative pathogens, as many of the proteins secreted via the T2S pathway constitute important virulence factors, includin | National Institutes of Health | 5/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $759,922 | Trans-NIH Recovery Act Research Support Antibiotic resistance is a looming global problem threatening some of the most significant public health gains of the past century. This critical health challenge, together with the emerging threat of biowarfare agents calls for the identification and dev | National Institutes of Health | 5/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $759,697 | Trans-NIH Recovery Act Research Support The overall goal of this ongoing research program is to understand the molecular basis of cell-cell interactions that regulate retinal neurogenesis during development and regeneration. The zebrafish (Danio rerio) provides a powerful genetic model in which | National Institutes of Health | 6/05/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $752,063 | Trans-NIH Recovery Act Research Support The goal of this research is to characterize expression and assembly of Treponema denticola (Td) surface proteins that mediate interactions with host tissue, thereby gaining insight into mechanisms of periodontal disease. We focus on analysis of two Td pr | National Institutes of Health | 5/05/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $745,250 | Trans-NIH Recovery Act Research Support Hox genes encode homeodomain-containing transcription factors that are expressed and function along the body axis in an AP-restricted manner corresponding to their position within the cluster. This pattern of global Hox expression is termed colinearity an | National Institutes of Health | 9/22/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $744,060 | Trans-NIH Recovery Act Research Support Hirschsprung disease, or aganglionic megacolon, is a congenital defect that affects 1 out of 5,000 live births and is characterized by a failure to form enteric nervous system (ENS) in a variable length of the hindgut. This potentially fatal condition res | National Institutes of Health | 9/03/2009 |
| THOMSON REUTERS (HEALTHCARE) INC. | $737,929 |
In support of the Health Information Technology for Economic and Clinical Health (HITECH) Act, the IDR will provide data services for use by the National Level Repository (NLR) in making payment determinations. Under this task order, the NLR Data Quality
This spending item is part of a $10,868,720 allocation.
See details
|
Health Care Financing Admin. (was Medicare and Medicaid Serv.) | 6/15/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $734,686 |
Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): This application addresses broad Challenge Area (03) Biomarker Discovery and Validation and specific Challenge Topic 03-MH-101 Biomarkers in mental disorders. Post-traumatic stress disorder (PTSD) is one of the more co
This spending item is part of a $994,788 allocation.
See details
|
National Institutes of Health | 9/24/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $728,684 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Helicobacter pylori remains the most prevalent infectious disease in the world, with up to100% of people colonized in some populations. Disease due to H. pylori is variable, however: only a minority of infected individ | National Institutes of Health | 7/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $724,055 | Trans-NIH Recovery Act Research Support In brain, sulfur metabolism exemplifies the principle of metabolic cooperation and furnishes cells with four major reagents critical for methylation reactions (S-adenosylmethionine), antioxidant capacity (glutathione), signaling (H2S), and cell volume reg | National Institutes of Health | 9/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $720,225 |
Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): When environmental exposure assessment studies provide feedback to the lay public, the resultant communications generally focus on the exposure assessment itself (e.g., serum levels) and not the relationship of the exp
This spending item is part of a $771,736 allocation.
See details
|
National Institutes of Health | 7/16/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $718,108 | Trans-NIH Recovery Act Research Support The sphingolipid storage diseases are a group of ~40 genetically distinct disorders that result from inherited deficiencies of lysosomal hydrolytic activities or lipid transport. Among this group is Niemann-Pick type C disease, an autosomal recessive diso | National Institutes of Health | 7/16/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $701,878 | Trans-NIH Recovery Act Research Support Recent evidence implicates cilia abnormalities as important in the etiology of Polycystic Kidney Disease. Our laboratory has defined an important role for polarity proteins, such as the apical transmembrane protein Crumbs3, in ciliogenesis. In the course | National Institutes of Health | 9/28/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $697,344 |
Trans-NIH Recovery Act Research Support Chaperones or heat shock proteins are found in all cells from bacteria to man and are among the most highly conserved and immunodominant molecules in nature. Originally thought to facilitate the three dimensional assembly of proteins it has become increas
This spending item is part of a $783,931 allocation.
See details
|
National Institutes of Health | 5/05/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $695,253 | Trans-NIH Recovery Act Research Support This competitive renewal continues to focus on the regulation of TGF-beta and Bmp7 in chronic and acute renal disease. Given that TGF-beta promotes renal interstitial fibrosis, whereas Bmp7 is thought to protect against this effect, the potential for deve | National Institutes of Health | 7/20/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $695,250 | Trans-NIH Recovery Act Research Support Adenoviruses are small, non-enveloped viruses containing a linear double stranded DNA genome that were first discovered in 1953. The human adenoviruses are associated with a variety of diseases including upper respiratory infections, gastrointestinal illn | National Institutes of Health | 5/21/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $682,168 |
Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area 15: Translational Science and specific Challenge Topic 15-RR-101: Applied Translational Technology Development. It is evident that prior to dialysis access failure (thrombosis), access flow decreases for eve
This spending item is part of a $1,000,000 allocation.
See details
|
National Institutes of Health | 9/22/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $681,339 | Trans-NIH Recovery Act Research Support This research proposes to use a newly developed 3D ultrasound method to measure volume blood flow. A wide variety of clinical applications would benefit from this development including estimation of cardiac output, monitoring of cerebrovascular diseases, | National Institutes of Health | 6/01/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $677,930 | We will collect and provide samples of snap-frozen colorectal cancers with associated frozen lymphocytes and germline DNA, in conjunction with comprehensive clinical annotation to the two Biospecimen Core resource (BCR) laboratories that work on The Cance | National Institutes of Health | 8/26/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $677,185 |
Trans-NIH Recovery Act Research Support Our goal is to determine the clinical, cognitive, imaging, genetic, and biochemical biomarker characteristics of the early (pre-dementia) stages of Alzheimer's disease (AD). The project builds on the NIA-funded AD Neuroimaging Initiative (ADNI1) and serve
This spending item is part of a $23,822,294 allocation.
See details
|
National Institutes of Health | 9/24/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $673,490 |
Trans-NIH Recovery Act Research Support DESCRIPTION (provided by investigator): This application addresses broad Challenge Area (08) Genomics and specific Challenge Topic, 08-HL-104: Assess genetic variation in African Americans and determine its effect on disease. Genome-wide association studi
This spending item is part of a $966,490 allocation.
See details
|
National Institutes of Health | 9/23/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $668,701 |
Trans-NIH Recovery Act Research Support This grant application is a response to Topic 15-OD (ORDR)-101. Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) is an inherited cardiac disease characterized by severe ventricular arrhythmias, as well as progressive replacement of healthy myocardiu
This spending item is part of a $999,229 allocation.
See details
|
National Institutes of Health | 9/21/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $667,701 |
Trans-NIH Recovery Act Research Support Program Director/Principal Investigator (Last, First, Middle): Kuhn, Richard J. 2 P01 AI055672-06A1 ABSTRACT The current understanding of alphavirus and flavivirus life cycles at the molecular level is incomplete because we lack a structural foundation fo
This spending item is part of a $3,946,282 allocation.
See details
|
National Institutes of Health | 9/01/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $665,932 |
This Task Order serves the following functions of support to a program of R24 (Infrastructure Development) and R21 (Preliminary Research, in 2008 and 2010) grantees directed at Patient Centered Outcomes Research on complex patient populations: - Creation
This spending item is part of a $2,927,937 allocation.
See details
|
Agency for Healthcare Research and Quality | 9/27/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $660,313 | Trans-NIH Recovery Act Research Support Blood-brain barrier (BBB) disruption represents a classic hallmark of central nervous system inflammation and it occurs in a variety of neuropathological conditions. BBB disruption involves remodeling of the brain endothelial cell surface, altered distrib | National Institutes of Health | 9/20/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $646,000 | Trans-NIH Recovery Act Research Support A Grand Opportunity for scientific advance has been created by the confluence of falling costs of genotyping, the development of statistical methods for genome-wide association studies (GWAS), and the creation of a substantial repository of genetic materi | National Institutes of Health | 9/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $641,176 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The importance of the bone marrow in hematopoiesis has been well documented. However, the function of bone marrow in tumor T cell immunity is not well understood. Regulatory T cells (Tregs), dendritic cells (DCs) and e | National Institutes of Health | 8/14/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $638,403 |
Trans-NIH Recovery Act Research Support This application addresses broad Challenge Are (06) Enabling Technologies and Specific Challenge Topic 06-CA-106 Data integration and visualization methods and tools. Prostate cancer is a highly prevalent disease in older men of the Western world, whose i
This spending item is part of a $998,992 allocation.
See details
|
National Institutes of Health | 9/28/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $622,948 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The cytochromes P450 are a ubiquitous superfamily of mixed function oxidases responsible for the oxidation of a vast number of compounds including the majority of drugs used by humans. In the course of our studies to d | National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $618,993 |
Trans-NIH Recovery Act Research Support In the next decade, breast cancer screening will likely be some combination of x-ray, ultrasound (US) and/or optical imaging, if this combination can be performed efficiently. Towards this goal, a proof-of-concept multimodality system is proposed in which
This spending item is part of a $853,883 allocation.
See details
|
National Institutes of Health | 9/14/2009 |
| MICHIGAN TECHNOLOGICAL UNIVERSITY | $609,971 |
Trans-NIH Recovery Act Research Support One potential result of climate change in the United States is increased frequency and intensity of wildland fires. These wildfire fires have the potential to destroy large amounts of public and private property, as was seen during the summer of 2003 and
This spending item is part of a $800,721 allocation.
See details
|
National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $605,088 | Trans-NIH Recovery Act Research Support Extracorporeal Support for Emergent (Uncontrolled) Donation Following Cardiac Death Introduction: The limited availability of donor organs for transplantation has led to an increased interest in the use of donation following cardiac death (DCD) donors. Ho | National Institutes of Health | 9/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $596,014 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): SAG (Sensitive to Apoptosis Gene), also known as RBX2/ROC2, or RNF7 (RING finger protein 7), is a stress-responsive component of SCF (Skp1, Cullins, F-box proteins) E3 ubiquitin ligase. Our previous work has shown that | National Institutes of Health | 7/16/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $593,332 |
Trans-NIH Recovery Act Research Support Scientific activities will be conducted over the two-year project period to address the following specific aims: Aim 1. To study cutoff points and estimate sensitivity and specifity for the ESAC, SORF, and ADOS-Toddler in relation to a best estimate diagn
This spending item is part of a $1,939,617 allocation.
See details
|
National Institutes of Health | 9/22/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $585,124 |
Trans-NIH Recovery Act Research Support The Southwest Oncology Group is an adult, multi-disease, multi-modality clinical cancer research organization with 35 Member Institutions, 29 Community Clinical Oncology Program (CCOP) institutions, including 7 Minority-Based CCOPs, 27 Urologic Cancer Out
This spending item is part of a $779,775 allocation.
See details
|
National Institutes of Health | 7/16/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $569,143 |
Trans-NIH Recovery Act Research Support Numerous genomic applications for cancer have become available offering the promise of effective and efficient cancer care tailored to the genetic profile of the patient or disease?Genomics and Personalized Medicine (GPM). The current regulatory structure
This spending item is part of a $4,000,000 allocation.
See details
|
National Institutes of Health | 9/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $563,242 | Trans-NIH Recovery Act Research Support Community Approaches to Cardiovascular Health: Pathways to Heart Health (CATCH-PATH) proposes to implement and evaluate a community-based participatory research (CBPR) intervention designed to reduce and ultimately eliminate disparities in cardiovascular | National Institutes of Health | 9/18/2009 |
| MICHIGAN CRITICAL CARE CONSULTANTS INC | $559,152 |
Trans-NIH Recovery Act Research Support This award includes funding under the American Recovery and Reinvestment Act of 2009 (ARRA) and is issued in response to Notice RFA-OD-09-008, Recovery Act Limited Competition: Biomedical Research, Development, and Growth to Spur the Acceleration of New T
This spending item is part of a $2,926,003 allocation.
See details
|
National Institutes of Health | 6/23/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $558,499 |
Trans-NIH Recovery Act Research Support The purpose of this grant is to build and test a data storage and dissemination system for confidential data, which obviates the need for users to build and secure their own computing environments. Recent advances in public utility (or 'cloud') computing
This spending item is part of a $618,494 allocation.
See details
|
National Institutes of Health | 7/27/2011 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $553,202 | Trans-NIH Recovery Act Research Support Lung cancer is an immense public health problem, and accounts for more years of life lost than the next three most common cause of cancer death combined. The goal of my laboratory is to understand mechanisms by which lung cancer tumors interact with their | National Institutes of Health | 5/21/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $552,193 |
Trans-NIH Recovery Act Research Support This research proposal, entitled 'Building on GWAS for NHLBI-diseases: the U.S. CHARGE consortium', will leverage existing population, laboratory and computational resources to identify susceptibility genes underlying genome-wide significant and well-repl
This spending item is part of a $27,554,408 allocation.
See details
|
National Institutes of Health | 9/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $546,488 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Acute otitis media results from a complex interplay of host defenses, environmental factors, and virulence characteristics of bacteria. Previous studies suggest that non-typeable Haemophilus influenza (NTHi), an import | National Institutes of Health | 7/17/2009 |
| PIXEL VELOCITY INCORPORATED | $534,348 |
Trans-NIH Recovery Act Research Support The overall goal of the proposed research program is to design and develop a noninvasive device for accurately measuring arterial compliance. Arterial compliance has been shown to be a strong indicator of many types of vascular disease, including cardiova
This spending item is part of a $664,541 allocation.
See details
|
National Institutes of Health | 7/15/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $532,936 |
Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Experiments are proposed to investigate the interaction between two risk factors for drug abuse: prenatal stress and being female. It is hypothesized that prenatal stress alters the neural systems that respond to novel
This spending item is part of a $644,216 allocation.
See details
|
National Institutes of Health | 7/16/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $518,832 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Challenge Area: (03) Biomarker Discovery and Validation Challenge Topic: Discovery of biomarkers for disease risk, progression or response to therapy in diseases of interest to NIDDK. 03-DK-101 Title: Biomarkers in Dia | National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $492,780 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The University of Michigan has an extensive program for care and use of laboratory animals campus-wide. This program includes animal housing facilities in 27 buildings on the Ann Arbor campus, two farm-based settings, | National Institutes of Health | 7/16/2009 |
| CENTER FOR SOCIAL GERONTOLOGY, INC., THE | $489,135 |
ARRA - Prevention and Wellness--State Territories and Pacific Islands The Michigan Tobacco Control Program (TCP) proposes to increase smoke-free public and affordable housing in Michigan by making 80% to 90% of all public and affordable housing smoke-free by 2011, including tribal units. The TCP wiwill collaborate with the S... Show more
This spending item is part of a $1,500,000 allocation.
See details
|
Centers for Disease Control and Prevention | 2/10/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $487,829 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Pancreas cancer kills almost 30,000 Americans each year, due both to local progression and to metastatic disease. We have pioneered the concept of maximizing systemic therapy, while incorporating high dose conformal ra | National Institutes of Health | 9/16/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $477,709 | Trans-NIH Recovery Act Research Support The 1000 Genomes Project aims to achieve a nearly complete catalog of common human genetic variants by generating high-quality sequence data surveying the genomes of >1000 individuals. This catalog will include SNPs, copy number variants, and short insert | National Institutes of Health | 9/18/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $466,616 |
Trans-NIH Recovery Act Research Support This is a revised, competitive renewal application for the Genetics of Microangiopathic Brain Injury (GMBI) study, initially funded in 2001 as an ancillary study to the Genetic Epidemiology Network of Arteriopathy (GENOA) and Family Blood Pressure Program
This spending item is part of a $1,666,669 allocation.
See details
|
National Institutes of Health | 8/04/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $463,337 | Trans-NIH Recovery Act Research Support Plastic bronchitis (PB) is a rare pediatric disease characterized by the presence of large fibrin or mucin casts in the airways. It is a significant health hazard in children associated with a high mortality rate (~50%). Presently, PB is anecdotally treat | National Institutes of Health | 7/14/2010 |
| ALTARUM INSTITUTE | $459,363 |
Recovery Act Comparative Effectiveness Research - AHRQ Over $1 billion is spent annually for contracted companies to deliver disease management programs to adults with chronic conditions, yet evidence of the effectiveness and cost savings of these programs is lacking. Published research suggests thatat disease ... Show more
This spending item is part of a $1,859,005 allocation.
See details
|
Agency for Healthcare Research and Quality | 9/28/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $458,410 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): One critical need for the development of reliable docking and scoring (d/s) is a large dataset containing high quality experimental protein-ligand complex structures, together with accurate binding affinity data. An on | National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $458,000 | Trans-NIH Recovery Act Research Support This Administrative Supplement proposes to consolidate in new space the existing resources of two complementary University of Michigan core facilities into one more productive, resilient, responsive, and cost-effective animal phenotyping core. A new senio | National Institutes of Health | 9/14/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $454,342 |
Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The proposed research will use hierarchical Bayesian modeling to tackle three interrelated problems in the analysis of population-based survey data: accounting for unequal probabilities of inclusion due to sample desig
This spending item is part of a $610,370 allocation.
See details
|
National Institutes of Health | 7/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $450,403 |
Trans-NIH Recovery Act Research Support The primary focus of this application is to study the total synthesis and biosynthesis of complex, biomedically significant natural products constituted of tetrahydroisoquinolines. The synthetic chemistry that will be developed shall be utilized to prepar
This spending item is part of a $652,948 allocation.
See details
|
National Institutes of Health | 5/07/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $450,403 |
Trans-NIH Recovery Act Research Support The primary focus of this application is to study the total synthesis and biosynthesis of complex, biomedically significant natural products constituted of tetrahydroisoquinolines. The synthetic chemistry that will be developed shall be utilized to prepar
This spending item is part of a $652,948 allocation.
See details
|
National Institutes of Health | 5/07/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $444,122 |
Trans-NIH Recovery Act Research Support Each year, more than a million women are diagnosed with breast cancer worldwide. Our understanding of the molecular mechanisms that underlie this disease are advancing rapidly, in part due to an enormous application of resources and effort to this problem
This spending item is part of a $2,919,697 allocation.
See details
|
National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $435,700 |
Trans-NIH Recovery Act Research Support This application, 'Epigenetic Biomarkers of Common Chronic Diseases,' addresses broad Challenge Area (03) Biomarker Discovery and Validation and specific Challenge Topic, 03-OD-101: Use of Epigenetic Signatures in Blood Cells to Predict Disease. Diabetes,
This spending item is part of a $998,684 allocation.
See details
|
National Institutes of Health | 9/23/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $431,995 | Trans-NIH Recovery Act Research Support The overall objective of this proposal is the strengthening of interdisciplinary research capacity in Ghana to address global health challenges faced by to low- and middle-income countries (LMICs). This focus reflects the situational analysis of the regio | National Institutes of Health | 9/27/2010 |
| EASTERN MICHIGAN UNIVERSITY | $431,807 | Trans-NIH Recovery Act Research Support Cancer cells have a high level of genetic instability. Naturally occurring 'fragile sites' on human chromosomes are correlated with genetic instability in cancer cells, but it is not well understood how and why these fragile sites generate instability. | National Institutes of Health | 4/26/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $424,876 | Trans-NIH Recovery Act Research Support This revised proposal, Developing Locally-Tailored Prevention Programming for Children of Incarcerated Mothers, uses a community-based participatory research (CBPR) approach to tailor and deliver an existing selective prevention program (Kumpfer's Strengt | National Institutes of Health | 5/07/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $424,875 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Mood disorders represent a class of devastating illnesses that have profound impact upon individuals, families, communities, employers, and health care systems. While many medications and therapies exist for the treatm | National Institutes of Health | 8/10/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $424,875 | Trans-NIH Recovery Act Research Support GABA modulation and negative affect in psychosis Schizophrenia frequently presents with clinically significant negative affect. In addition to co-morbid depression and anxiety disorders (up to 60 O/O), patients show high levels of trait negative affectivi | National Institutes of Health | 9/01/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $424,875 | Trans-NIH Recovery Act Research Support The morphology of a dental crown is controlled by a strictly regulated spatio-temporal expression of ameloblast specific genes encoding for enamel matrix proteins. Once ameloblasts enter the differentiation stage along the dentino-enamel junction (DEJ) an | National Institutes of Health | 5/01/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $424,875 | Trans-NIH Recovery Act Research Support Suicide, with its related mortality and morbidity, represents a significant and preventable loss of human life. Existing research indicates that problematic alcohol and drug use are closely linked to both fatal and non-fatal suicide attempts. Given the st | National Institutes of Health | 5/21/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $424,841 | Trans-NIH Recovery Act Research Support Recent research has shown that mortality rates increase during economic expansions and decrease during recessions. This counterintuitive finding has been replicated in several industrialized countries, but important questions remain regarding the relative | National Institutes of Health | 9/02/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $424,832 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Hypertension during pregnancy affects 5-8% of pregnancies in the United States and contributes to serious complications for both the fetus and mother. Hypertension may lead to pre-eclampsia, which can restrict fetal gr | National Institutes of Health | 6/04/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $422,550 | Trans-NIH Recovery Act Research Support In patients with chronic obstructive pulmonary disease (COPD), which is characterized by bacterial colonization of the airways, co-infection with respiratory viruses further impairs host defenses, leading to bacterial overgrowth and infection, as well as | National Institutes of Health | 5/15/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $421,070 | Trans-NIH Recovery Act Research Support Human skin, like all other organs, undergoes alterations as a consequence of the passage of time. In aged human skin, the dermal connective tissue architecture undergoes progressive degradation, which impairs skin function and causes skin to become thin a | National Institutes of Health | 9/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $419,168 | Trans-NIH Recovery Act Research Support We propose to expand and maintain the Adult to Adult Living Donor Liver Transplantation Cohort Study Data Coordinating Center (A2ALL DCC) that will support a consortium of transplant centers in conducting continued observational and interventional researc | National Institutes of Health | 2/03/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $418,766 | Trans-NIH Recovery Act Research Support This proposal will establish a new research direction and develop novel techniques for my laboratory while promoting a new collaboration between my lab and that of my co- investigator, Dr. Yehoash Raphael. We plan to develop a guinea pig model of vestibul | National Institutes of Health | 6/05/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $416,966 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Cleft palate is a highly prevalent craniofacial malformation that affects approximately one in 700 newborns in the U.S. Studies on small numbers of children have raised the concern that repair of the cleft palate incre | National Institutes of Health | 6/02/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $416,194 |
Trans-NIH Recovery Act Research Support Translational research is the cornerstone of health care advances. However, facilitating communication between research participants or consumers and investigators has been a challenge for decades. Divergent consumer and investigator perspectives have led
This spending item is part of a $905,298 allocation.
See details
|
National Institutes of Health | 7/14/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $415,561 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Our ultimate goal is to develop a new and simple method to microencapsulate drugs and other bioactive substances, particularly biomacromolecules such as proteins and peptides, in biodegradable controlled-release polyme | National Institutes of Health | 7/15/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $414,435 | Trans-NIH Recovery Act Research Support We concluded the work on the use of the asynchronous magnetic bead rotation (AMBR) sensor, for the measurement of individual cell growth. The AMBR sensor allows for the measurement of nanoscale growth dynamics of individual bacterial cells, over multiple | National Institutes of Health | 4/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $413,430 | Trans-NIH Recovery Act Research Support Disturbances in maternal care have been associated with impairments in affective and cognitive development of the offspring. In humans, there is growing evidence that postpartum mood disorders have a negative impact on the mother-child relationship, and t | National Institutes of Health | 6/08/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $413,273 |
Trans-NIH Recovery Act Research Support In August 2011, the second manuscript for this project was accepted for publication in the Journal of Autoimmunity. The article entitled G?Antigenic Challenge in the Etiology of Autoimmune Disease in WomenG? will be published in a special issue regarding
This spending item is part of a $438,412 allocation.
See details
|
National Institutes of Health | 5/18/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $412,013 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Mucosal surfaces are constantly exposed to antigens, infectious agents and the indigenous microbiota. Sequential infections are being increasingly recognized to be a determining factor in the outcome of an immune respo | National Institutes of Health | 7/22/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $411,666 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The macromolecular machinery that supports cellular functioning principally operates on the scale of nanometers, and nanoscale science and technology are broadly recognized as important emerging disciplines, with broad | National Institutes of Health | 5/27/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $411,464 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): This project will define the essential mechanics of macropinosome closure. Macropinocytosis and morphologically analogous movements of membrane and the actin cytoskeleton are important in epithelial physiology and host | National Institutes of Health | 7/21/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $409,386 | Trans-NIH Recovery Act Research Support Lafora disease (LD) is an autosomal recessive and incurable disease with characters of progressive myoclonus epilepsy (PME), severe neurological deterioration, and the accumulation of starch-like glycogen inclusion bodies (LB) mainly in the brain, muscle, | National Institutes of Health | 5/15/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $409,000 | Trans-NIH Recovery Act Research Support Viruses are potent cancer-inducing agents. While the clinical effects of cancer are obvious, its cellular and molecular causes are not fully understood. Here we propose to study the cellular entry mechanisms of polyomavirus (Py), a non-enveloped DNA tumor | National Institutes of Health | 9/21/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $407,929 |
Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Nephrotic Syndrome, characterized by massive proteinuria, hypoalbuminemia and edema, is one of the most frequently seen kidney diseases in children. Despite extensive research, the pathogenesis of this disease for the
This spending item is part of a $439,355 allocation.
See details
|
National Institutes of Health | 7/20/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $405,843 |
Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): For over half a century, androgen deprivation therapy (ADT) has been known to have beneficial effects on prostate cancer due to the testosterone dependence of prostate tumor cells, yet its optimal use still remains und
This spending item is part of a $482,660 allocation.
See details
|
National Institutes of Health | 7/13/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $404,623 |
Recovery Act Comparative Effectiveness Research - AHRQ Bipolar is a severe and lifelong illness affecting 4.5% of the population ? about 14 million people in the U.S. It is one of the top 10 most disabling medical conditions worldwide according to the World Health Organization. Traditionally, the mooood stabili... Show more
This spending item is part of a $9,784,863 allocation.
See details
|
Agency for Healthcare Research and Quality | 9/28/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $400,000 |
Trans-NIH Recovery Act Research Support Diabetes Prevention Program Outcomes Study (DPPOS) Diabetes Prevention Program (DPP) demonstrated that lifestyle and metformin reduce the risk of diabetes (DM) by 58% and 31% (NEJM 346;393-403,2002). The DPPOS, now in year 7, aims to determine whether re
This spending item is part of a $2,000,000 allocation.
See details
|
National Institutes of Health | 9/28/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $399,611 | Trans-NIH Recovery Act Research Support We propose to develop and maintain a Data Coordinating Center (DCC) that will provide support for a network of clinical sites studying chronic pediatric liver disease. Specifically we will continue, expand, and merge the efforts of investigators from the | National Institutes of Health | 8/05/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $396,147 | Trans-NIH Recovery Act Research Support Project Summary To address the shortcomings of current methods of monitoring stents for occlusion, the goal of the proposed work is to develop and verify the performance of a system that wirelessly monitors the buildup of occlusive material in a stent. Th | National Institutes of Health | 7/07/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $395,660 | Trans-NIH Recovery Act Research Support This is a revised resubmission of a competitive renewal application for a Rheumatology Training Grant that was first funded in 1976, and that aims to prepare qualified individuals for careers as independent investigators in areas of basic and clinical res | National Institutes of Health | 9/22/2009 |
| DISS LLC | $390,806 | ARRA Intramural Research Equipment: This requirement provides consolidated equipment for the NIAID (National Institute of Allergy and Infectious Diseases) Intramural Research Program for influenza studies. The deliverables include: integrated remote tele | National Institutes of Health | 10/23/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $389,120 | Trans-NIH Recovery Act Research Support Calreticulin is an endoplasmic reticulum (ER) chaperone that promotes folding and assembly of glycoproteins, including major histocompatibility complex (MHC) class I molecules. Calreticulin also has the capacity to direct exogenous antigens onto the MHC c | National Institutes of Health | 9/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $386,666 | Trans-NIH Recovery Act Research Support We are assaying whether mouse adenovirus type-1 (MAV-1) uses fiber knob RGD for attachment or entry in fibroblasts, before we move to the resource-intensive primary cells it infects in vivo: monocytes and brain endothelial cells. Suspension cells have bee | National Institutes of Health | 9/07/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $386,250 | Trans-NIH Recovery Act Research Support We have performed additional studies to understand the activation of the NLRP3 inflammasome. We found that al stimuli tested including ATP, bacterial toxins, and particulate matter (silica) induce K+ efflux. The new studies have revealed that K+ efflux is | National Institutes of Health | 6/21/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $383,606 |
Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Abstract: Facultative intracellular Brucella species cause brucellosis in animals and humans and have been classified as NIAID category B priority pathogens. Brucella infects the body via the respiratory tract, the ski
This spending item is part of a $418,502 allocation.
See details
|
National Institutes of Health | 7/21/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $381,616 |
Trans-NIH Recovery Act Research Support Numerous genomic applications for cancer have become available offering the promise of effective and efficient cancer care tailored to the genetic profile of the patient or disease?Genomics and Personalized Medicine (GPM). The current regulatory structure
This spending item is part of a $4,000,000 allocation.
See details
|
National Institutes of Health | 9/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $381,419 |
Trans-NIH Recovery Act Research Support This application entitled 'Development of a Brief Screener for Research in Autism Spectrum Disorders' addresses broad challenge area (04) Clinical Research, 04-MH-101* Autism: Addressing the challenge. The proposal aims to develop a research screening ins
This spending item is part of a $996,692 allocation.
See details
|
National Institutes of Health | 9/28/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $380,800 | Trans-NIH Recovery Act Research Support This is a proposal to support the purchase of a Scanco CT100 specimen micro computed tomography scanner (?CT) that is to be part of an Imaging Core Facility at the University of Michigan School of Dentistry. This instrument will mainly support NIH-sponsor | National Institutes of Health | 12/31/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $380,648 |
Trans-NIH Recovery Act Research Support The objective of this grant is to implement a high throughput screen for small molecules that potentiate the activity of FosB, a transcription factor that promotes resilience and antidepressant-like responses in several animal models and is deficient in t
This spending item is part of a $693,115 allocation.
See details
|
National Institutes of Health | 9/24/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $379,710 | Trans-NIH Recovery Act Research Support The epithelium of the small intestine undergoes a remarkable series of morphogenic changes during its development. The endodermally derived epithelial tube is initially comprised of a single layer of short columnar cells. Between E10.5 and E14.5, the epit | National Institutes of Health | 8/16/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $379,397 | Trans-NIH Recovery Act Research Support Atherosclerotic cardiovascular disease is the main cause of the long observed early mortality in rheumatoid arthritis (RA) patients. In this project, the possibility that the RA shared epitope (SE) is directly contributing to atherosclerosis development w | National Institutes of Health | 9/22/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $374,137 | Trans-NIH Recovery Act Research Support Abstract An exciting development in the innate immunity field is the discovery that macrophages enlist autophagy to protect their cytoplasm from infection. Nutrient deprivation has long been known to induce autophagy, but how infection rapidly triggers th | National Institutes of Health | 8/14/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $373,893 | Trans-NIH Recovery Act Research Support The studies proposed here will examine a red marine algae extract for ability to inhibit the outgrowth of abnormal colonic epithelial cells. The source of the extract is the North Atlantic red algae, Lithothamnium coralliodides. The extract is rich in Ca2 | National Institutes of Health | 5/15/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $373,890 | Trans-NIH Recovery Act Research Support There are over 10 million cancer survivors whose needs for psychosocial care are not being met. Although some supportive-educative programs exist, they are expensive to deliver and do not address communication problems of patients and their family caregiv | National Institutes of Health | 5/05/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $373,309 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Toxoplasma gondii and Listeria monocytogenes are intracellular pathogens classified as NIAID category B priority agents. Both organisms can lead to significant disease and mortality in immunodeficient or immunocompeten | National Institutes of Health | 7/22/2009 |
| Survey Sciences Group LLC | $371,000 |
Trans-NIH Recovery Act Research Support Most college stuents with mental disorders do not receive treatment, and over 80% of those who die by suicide have never made contact with campus mental health services. Knowledge, stigma, and other health beliefs represent significant barriers to help-se
This spending item is part of a $988,937 allocation.
See details
|
National Institutes of Health | 9/23/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $368,861 | Trans-NIH Recovery Act Research Support We are actively investigating the role of a zinc finger transcription factor called ZBP-89 in the regulation of cell growth. This factor was expression cloned in my lab using a DNA element from the gastrin promoter that mediates EGF regulation. Recent stu | National Institutes of Health | 7/28/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $364,380 |
Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Adjuvant systemic therapy, including chemotherapy, hormonal therapy, and trastuzumab, markedly reduces the risk of metastatic recurrence and death for selected patients with breast cancer. Guideline-concordant use of c
This spending item is part of a $1,197,369 allocation.
See details
|
National Institutes of Health | 8/11/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $363,704 |
Trans-NIH Recovery Act Research Support ARRA - Socioeconomic Disparities in Young Adult Health In the United States, large and persistent health disparities exist across the life course. Reducing these disparities is a top priority for policymakers and the public. Of particular importance, f
This spending item is part of a $674,761 allocation.
See details
|
National Institutes of Health | 9/22/2009 |
| EASTERN MICHIGAN UNIVERSITY | $361,432 | Trans-NIH Recovery Act Research Support The purpose of this study is to develop and test the feasibility of using individually tailored theoretically-based intervention strategies to promote mammpgraphy screening among non-adherent Chinese-American women. | National Institutes of Health | 5/11/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $359,897 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The objective of this proposal is to acquire a non-invasive 3D quantitative molecular imaging system that allows for in vivo, ex vivo and in vitro imaging. The system, called the IVIS Spectrum from Caliper LifeSciences | National Institutes of Health | 1/28/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $358,131 | Trans-NIH Recovery Act Research Support A. Introduction and specific aims The human immunodeficiency virus (HIV) causes a lethal syndrome (acquired immunodeficiency syndrome) characterized by CD4+ T cell depletion and resultant immunodeficiency. HIV has caused a worldwide epidemic that has ki | National Institutes of Health | 6/07/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $350,000 |
Trans-NIH Recovery Act Research Support We are embarking on contributing to a large catalogue of DNA sequence variation in phenotyped samples and to pioneering the application of this depth and scale of data to the analysis of key cardiovascular phenotypes. We propose to do this by (1) performi
This spending item is part of a $24,870,017 allocation.
See details
|
National Institutes of Health | 9/28/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $348,398 | Trans-NIH Recovery Act Research Support This application requests R21 exploratory funds to develop methodology and tools leading to a comprehensive registry of biomarker and health variables found in publicly available secondary data collections. The proposed pilot will begin with data drawn fr | National Institutes of Health | 8/14/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $337,690 | Trans-NIH Recovery Act Research Support Ultraviolet (UV) irradiation from the sun is a well-recognized, otent environmental insult, and skin is directly exposed to UV irradiation. Long-term exposure to UV irradiation damages human skin connective tissue and promotes formation of skin cancer, th | National Institutes of Health | 9/24/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $335,604 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Improvements in the treatment of brain tumors have produced little impact on outcomes over the past three decades. Still, survival for both pediatric and adult brain tumors is known to be maximized by radiographically | National Institutes of Health | 8/31/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $331,199 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): There has been a long standing research and clinical collaboration between Urology and Reproductive Endocrinology at the University of Michigan. This proposal describes the qualifications and experience of the Reproduc | National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $326,934 | Trans-NIH Recovery Act Research Support No abstract available. | National Institutes of Health | 9/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $326,431 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Radioresistance markedly impairs the efficacy of radiotherapy and involves cell signal transduction pathways that prevent radiation-induced cell death. Proteins in the Bcl-2 family are central and dual regulators of ap | National Institutes of Health | 7/16/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $321,124 | Trans-NIH Recovery Act Research Support Association studies provide a powerful approach for locating alleles that contribute to disease susceptibility and phenotypic variation. Since population-genetic processes play a central role in generating patterns of statistical association between disea | National Institutes of Health | 8/31/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $320,490 | Trans-NIH Recovery Act Research Support This project will utilize high-throughput genetic technologies in a major longitudinal behavioral study and renew the biomedical research community by building scientific partnerships for the integration of behavioral and genetic science. The 7,000 indivi | National Institutes of Health | 9/21/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $317,307 | Trans-NIH Recovery Act Research Support The University of Michigan Clinical and Translational Sciences Award (UM CTSA) will focus the formidable strengths of one of the world's finest research institutions on supporting and facilitating clinical and translational 'team science'. The UM CTSA wil | National Institutes of Health | 9/21/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $313,873 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): This center program seeks to evaluate the performance of genomic sequence information for predicting health and disease above and beyond traditional risk factors. To accomplish this objective we will develop statistica | National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $312,976 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Neurexins play an important role at the synapse, promoting adhesion and communication between neurons. More than 2000 neurexin isoforms are generated through a process called alternative splicing. WORKING MODEL: Neurex | National Institutes of Health | 7/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $310,588 |
ARRA Accelerating Adoption of Comparative Effectiveness Research (CER) We know from existing comparative effectiveness research that certain feeding practices and therapeutics result in overall harm to preterm infants. We have shown that a large number of preterm infants are currently exposed to thesese therapies. This proposa... Show more
This spending item is part of a $2,841,474 allocation.
See details
|
Office of Assistant Secretary for Planning and Evaluation | 9/20/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $309,000 | Trans-NIH Recovery Act Research Support Opiate drug abuse and human immunodeficiency virus (HIV) infection/AIDS are two major public health problems. HIV-associated sensory neuropathy (HIV-SN) is the most common neurological complication of HIV infection. The symptoms of HIV-SN are dominated by | National Institutes of Health | 5/04/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $309,000 | Trans-NIH Recovery Act Research Support DESCRIPTION, OVERALL (provided by applicant): The focus for the George M. O'Brien Kidney Centers has been basic science investigation that has very successfully defined kidney structure, function and disease mechanisms. New technologies now provide opport | National Institutes of Health | 8/31/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $309,000 | Trans-NIH Recovery Act Research Support Michigan Diabetes Research and Training Center The Michigan Diabetes Research and Training Center (MDRTC) is a multidisciplinary unit of The University of Michigan Health System. The MDRTC is now in its thirtieth year, having been funded by the NIH/NIDDK | National Institutes of Health | 12/04/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $308,407 | Trans-NIH Recovery Act Research Support Conditions have been optimized for conducting chromatin immunoprecipitation assays with low background and sufficient resolution to give clear signals after ChIP-Seq analysis. We anticipate commencing ChIP-Seq analysis of osteoblast differentiation in the | National Institutes of Health | 9/01/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $307,094 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The central goal of this project is to produce a harmonized dataset of U.S. family and fertility surveys spanning the 1955-2002 period, including the 1955 and 1960 Growth of American Families (GAP); the 1965 and 1970 N | National Institutes of Health | 7/29/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $306,954 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Hurricane Katrina struck New Orleans, Louisiana, on the morning of August 29, 2005. The magnitude of the displacement that resulted was immense: the city's entire population of 455,000 was forced to leave the city and | National Institutes of Health | 9/28/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $304,163 | Trans-NIH Recovery Act Research Support Although the prototypes of breast cancer suppressor genes, BRCA1 and BRCA2, have been identified, the genetic defects responsible for the majority of breast cancer remain elusive. In addition, essentially all cancer suppressor genes identified are autosom | National Institutes of Health | 8/28/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $301,251 | A full-text search engine is critical to increasing the reuse value of narrative documents stored in electronic health records (EHR). A prominent barrier preventing the effective use of such systems originates from usersG?? lack of search expertise and/or | National Institutes of Health | 9/21/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $300,000 | Trans-NIH Recovery Act Research Support DESCRIPTION, OVERALL (provided by applicant): Recent advances in basic research techniques have led to an explosion of information and interest in the role of gastrointestinal peptides in health and disease. The function of these peptides has been shown t | National Institutes of Health | 7/20/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $296,563 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Protein drugs are currently administered systemically by injections. For individuals requiring chronic therapy, self administration with a needle is an unpleasant everyday experience. Development of injectable biodegra | National Institutes of Health | 7/16/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $289,456 | Trans-NIH Recovery Act Research Support The long-term objective of the proposed research is to elucidate the mechanisms of drug- and xenobiotic- mediated inactivation, degradation, and turnover of cytochrome P450 enzymes. Nitric oxide synthase (NOS), the most highly regulated cytochrome P450 en | National Institutes of Health | 8/31/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $288,521 | Trans-NIH Recovery Act Research Support This is a Competitive Revision for GM50403 of Notice Number (NOT-OD-09-058), and Notice Title: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. The state of Michigan has been particularly hard hit by the economic | National Institutes of Health | 1/29/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $288,217 | Trans-NIH Recovery Act Research Support This administrative supplement for Accelerating the Science (ACC) is linked to a new equipment (EQ_Research Equipment for the Advancement of Science) request which together encompass activities from the aims of three Cores of the parent grant G?? Core A, | National Institutes of Health | 7/10/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $281,370 | Trans-NIH Recovery Act Research Support Huntingtin Interacting Protein 1 (HIP1) is a clathrin, actin and inositol lipid binding protein that has been implicated in neurodegeneration by virtue of its interaction with huntingtin, the protein mutated in Huntington's disease. It is also associated | National Institutes of Health | 9/03/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $273,821 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): With the support of the current funded R01, we have modified and optimized our nanovectors for tumor targeted delivery of siRNA/shRNA specific to Bcl-2 and Bcl-xL. We found unexpectedly that our nanovectors also target | National Institutes of Health | 9/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $272,133 | Trans-NIH Recovery Act Research Support We propose to develop and maintain a Data Coordinating Center (DCC) that will support a consortium of transplant centers (Clinical Centers) by conducting epidemiological research on the medical and functional outcomes of living individuals who have donate | National Institutes of Health | 9/21/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $272,107 | Trans-NIH Recovery Act Research Support Asthma is the most common chronic disease of childhood in the United States. Children living in poverty and in urban centers, many of whom are persons of color and are at greater risk for environmental exposures, suffer disproportionately from asthma. Man | National Institutes of Health | 7/01/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $271,091 | Trans-NIH Recovery Act Research Support Diabetes is a world-wide major cause of morbidity and mortality that is associated with disturbances in cell function that result in the loss of glucose-stimulated insulin secretion for control of blood glucose. Recent studies demonstrated an associatio | National Institutes of Health | 12/18/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $269,265 | ARRA - Public Health Traineeship Program The University of Michigan School of Public Health is committed to being a leading contributor to the achievement of the national Healthy People in Healthy Communities objectives, as outlined in Healthy People 2010. The second goal of Healthy People 2010 | Health Resources and Services Administration | 9/03/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $269,263 | Trans-NIH Recovery Act Research Support Bone is a complex system whose critical function is to be sufficiently stiff and strong to support the physical forces associated with daily activities. Understanding how genetic and environmental variants compromise this function is critical to fully und | National Institutes of Health | 1/12/2012 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $264,156 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): These studies have direct relevance for improving our understanding of the developmental defects associated with Chd7 deficiency. Precise regulation of gene expression is critical for normal development of most tissues | National Institutes of Health | 7/17/2009 |
| COMPENDIA BIOSCIENCE, INC. | $263,987 | Trans-NIH Recovery Act Research Support Development of Oncomine Professional as a Platform for Biopharmaceutical Research (Supplement): DNA microarray studies, largely sponsored by the NIH and other granting agencies, have generated a wealth of data uncovering the complex gene expression patter | National Institutes of Health | 9/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $261,953 |
Trans-NIH Recovery Act Research Support The systemic vasculitides are a group of diseases characterized by severe inflammation of blood vessels leading to arterial stenosis or occlusion, and organ damage or death if untreated. Two related vasculitides, Wegener's granulomatosis (WG) and microsco
This spending item is part of a $1,000,000 allocation.
See details
|
National Institutes of Health | 9/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $259,984 | Trans-NIH Recovery Act Research Support Stem cells continuously produce highly differentiated but short-lived cells, such as blood, skin, intestinal epithelium, and sperm cells throughout life. Asymmetric stem cell division, which produces one self-renewed stem cell and one differentiated cell, | National Institutes of Health | 7/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $259,325 |
Trans-NIH Recovery Act Research Support The mission of the Southwest Oncology Group is to conduct clinical trials to prevent and treat cancer in adults, and to improve the quality of life for cancer survivors. The Group's network includes more than 5,000 physicians who practice at nearly 550 in
This spending item is part of a $410,460 allocation.
See details
|
National Institutes of Health | 6/11/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $256,994 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): During the previous funding period we discovered the pathogenic role of two proteins in neurological disease. By positional cloning the mouse neurological mutant pale tremor, with neurodegeneration in peripheral gangli | National Institutes of Health | 7/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $256,406 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The long-term objectives of this proposal are to develop compliant, thoracic artificial lungs (cTALs) that can be used as a bridge to transplant for patients with end-stage respiratory disease. As a bridge to lung tran | National Institutes of Health | 7/16/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $254,500 | Trans-NIH Recovery Act Research Support Obesity is the primary risk factor for diabetes and multiple other metabolic diseases. During the development of obesity, energy intake exceeds energy expenditure, and the excess energy is stored as triglycerides in adipose tissue. Adipose tissue secret | National Institutes of Health | 12/18/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $250,901 | Trans-NIH Recovery Act Research Support PROJECT SUMMARY (See instructions): There are four separate requests contained within this Administrative Supplement (one for each investigator and one for the Cell Biology Core). The most significant portion of the budget is devoted to the purchase of t | National Institutes of Health | 8/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $250,000 |
Trans-NIH Recovery Act Research Support This is a proposal to validate the accuracy of a multi-gene Lung Cancer Risk Test (LCRT). An accurate LCRT may be used to design more efficient lung cancer screening and/or chemoprevention studies by enabling enrollment of the highest risk individuals, re
This spending item is part of a $799,426 allocation.
See details
|
National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $250,000 |
Trans-NIH Recovery Act Research Support This is a proposal to validate the accuracy of a multi-gene Lung Cancer Risk Test (LCRT). An accurate LCRT may be used to design more efficient lung cancer screening and/or chemoprevention studies by enabling enrollment of the highest risk individuals, re
This spending item is part of a $1,649,791 allocation.
See details
|
National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $248,087 | Trans-NIH Recovery Act Research Support All 19-carbon androgens derive from 21-carbon steroids via sequential 17-hydroxylase and 17,20-lyase activities of cytochrome P450c17 (CYP17A1). The complex chemistry of the 17,20-lyase reaction is selectively stimulated up to 10-fold by cytochrome b5 (b5 | National Institutes of Health | 6/13/2012 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $243,558 | Trans-NIH Recovery Act Research Support Principal Investigator/Program Director (Last, first, middle): Han, Zhe RESEARCH & RELATED Other Project Information 1. * Are Human Subjects Involved? m Yes l No 1.a. If YES to Human Subjects Is the IRB review Pending? m Yes m No IRB Approval Date: Exempt | National Institutes of Health | 7/16/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $238,719 | Trans-NIH Recovery Act Research Support The proposed research will focus on a broad set of aims that center around the development and application of the nickel-catalyzed, silane-promoted reductive coupling of aldehydes and alkynes to generate allylic alcohols. Allylic alcohols are a common str | National Institutes of Health | 8/31/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $237,599 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Lung transplantation (LTX) reduces morbidity and mortality from respiratory failure, but acute and long-term outcomes remain poor. Primary lung graft failure occurs in up to 20% of recipients, and by 5 years, over half | National Institutes of Health | 7/16/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $234,602 | Trans-NIH Recovery Act Research Support Abdominal aortic aneurysms (AAAs) comprise the 10th leading cause of death in Caucasian males 65-74 years of age and accounted for nearly 16,000 deaths overall in the year 2000. Understanding the pathophysiology of AAAs is an important undertaking. Clinic | National Institutes of Health | 7/16/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $234,405 | Trans-NIH Recovery Act Research Support This is an application for competitive revision of NIH 5R01DK078056 under NOT-OD-09-058, NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications.The ongoing epidemic of obesity in the United States represents a public he | National Institutes of Health | 9/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $234,339 | Trans-NIH Recovery Act Research Support This project expands the scope of the parent project by examining the role of G?pregnancy scaresG? in the processes leading to unintended childbearing. Our aim is to accelerate the science of the project by incorporating measures of pregnancy scares into | National Institutes of Health | 9/28/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $233,408 |
Trans-NIH Recovery Act Research Support Causal Estimates of Neighborhood Poverty on Health & Mortality Project Summary Abstract The disparities in the distribution of goods and services, and hazards and opportunities across space are increasing, underscoring the growing connection between place
This spending item is part of a $382,223 allocation.
See details
|
National Institutes of Health | 9/28/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $232,272 |
Trans-NIH Recovery Act Research Support The Southwest Oncology Group is an adult, multi-disease, multi-modality clinical cancer research organization with 35 Member Institutions, 29 Community Clinical Oncology Program (CCOP) institutions, including 7 Minority-Based CCOPs, 27 Urologic Cancer Out
This spending item is part of a $689,999 allocation.
See details
|
National Institutes of Health | 9/21/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $231,750 | Trans-NIH Recovery Act Research Support Bone degenerative diseases such as osteoporosis, periodontitis, and rheumatoid arthritis are major health care concerns for the elderly population that is rapidly increasing in the US. An osteoporotic fracture can cause significant morbidity and mortality | National Institutes of Health | 4/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $231,149 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The last two decades mark a conceptual revolution in immune recognition, switching from one based on engagement of clonal receptor to one that integrates pattern recognition with clonal recognition. The pathogen-associ | National Institutes of Health | 7/19/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $229,035 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The long-term goal of our studies is to understand how prostaglandin (PG) synthesis is regulated. There are two PGH synthases (PGHS-1 and -2) each able to catalyze the committed step in PG formation-oxygenation of the | National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $228,991 |
Recovery Act Comparative Effectiveness Research - AHRQ Over $1 billion is spent annually for contracted companies to deliver disease management programs to adults with chronic conditions, yet evidence of the effectiveness and cost savings of these programs is lacking. Published research suggests thatat disease ... Show more
This spending item is part of a $1,859,005 allocation.
See details
|
Agency for Healthcare Research and Quality | 9/28/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $228,000 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Degenerative diseases of the retina are responsible for devastating visual handicap affecting millions of individuals worldwide. Monogenic disorders with relatively early age-of-onset have been mapped to over 200 genet | National Institutes of Health | 8/31/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $216,816 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Neural circuits are the functional and structural units of the nervous system. Defects in neural circuit function and development lead to a variety of neurological disorders. We are interested in understanding how info | National Institutes of Health | 9/09/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $213,188 | Trans-NIH Recovery Act Research Support As human retinas are rich in autofluorescent compounds, such as lipofuscin, it is not practical to use immunofluorescence methods to localize molecules in tissue sections during basic eye research or in clinical evaluations of eye pathology; this is espec | National Institutes of Health | 8/04/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $211,974 |
Trans-NIH Recovery Act Research Support The broad aim of this Grand Opportunity Grant is to understand how race-based social stress, racial/ethnic (R/E) identity, and biological functioning contribute to health and healthy aging. Using the Maryland Adolescent Development in Context Study (MADIC
This spending item is part of a $900,235 allocation.
See details
|
National Institutes of Health | 9/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $207,732 | Trans-NIH Recovery Act Research Support Latinos in the US carry a disproportionate burden of type-2 diabetes. Research has implicated life course socioeconomic position as a major factor in the development of chronic diseases, such as type-2 diabetes; yet most evidence is limited to non-Hispani | National Institutes of Health | 4/28/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $204,152 |
Trans-NIH Recovery Act Research Support We propose to study US trends in the prevalence of cognitive impairment and dementia by performing a new Aging, Demographics, and Memory Study (ADAMS 2010) that uses a similar methodology to that employed for the original NIA-funded study performed in 200
This spending item is part of a $1,100,000 allocation.
See details
|
National Institutes of Health | 9/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $203,863 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Genetic information is usually represented as linear arrays on chromosomes, yet nuclear DNA exists in a highly compacted form in which access to individual genes must be considered as a three-dimensional problem. Cytol | National Institutes of Health | 7/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $203,732 | Trans-NIH Recovery Act Research Support Angiogenesis, the sprouting of new capillary blood vessels from existing vasculature, is a complex biological process of critical importance to the treatment of numerous pathologies and the success of tissue engineering. Amongst the many promising strateg | National Institutes of Health | 8/28/2009 |
| COLORADO STATE UNIVERSITY | $202,545 |
Trans-NIH Recovery Act Research Support The primary focus of this application is to study the total synthesis and biosynthesis of complex, biomedically significant natural products constituted of tetrahydroisoquinolines. The synthetic chemistry that will be developed shall be utilized to prepar
This spending item is part of a $652,948 allocation.
See details
|
National Institutes of Health | 5/07/2009 |
| COLORADO STATE UNIVERSITY | $202,545 |
Trans-NIH Recovery Act Research Support The primary focus of this application is to study the total synthesis and biosynthesis of complex, biomedically significant natural products constituted of tetrahydroisoquinolines. The synthetic chemistry that will be developed shall be utilized to prepar
This spending item is part of a $652,948 allocation.
See details
|
National Institutes of Health | 5/07/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $202,171 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The claim behind theory of mind is that certain core conceptions organize and enable our everyday understanding of the social world. In particular, social cognition is based on thinking of people in terms of their ment | National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $200,850 | Trans-NIH Recovery Act Research Support DESCRIPTION, OVERALL (provided by applicant): The University of Michigan is ideally poised to house a MAPP Discovery Site. The faculty of the Chronic Pain and Fatigue Research Center (CPFRC) are internationally known for translational research in fibromya | National Institutes of Health | 9/28/2009 |
| TRINITY HEALTH CORPORATION | $199,900 | Trans-NIH Recovery Act Research Support This award is designed to fund a research nurse navigator program with the goal of accelerating the tempo of scientific research by increasing registration and patient recruitment to national cooperative group research trials and allow for job creation f | National Institutes of Health | 9/10/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $196,072 | Trans-NIH Recovery Act Research Support The research proposed here will use archival data and multi-level/hierarchal spatial modeling to examine the geography of alcohol outlets and violence, over time, in the city of Boston. We will determine whether and how place matters in regard to the rela | National Institutes of Health | 3/13/2012 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $196,041 | Trans-NIH Recovery Act Research Support Proopiomelanocortin (POMC) neurons within the arcuate nucleus are a critical component of the hypothalamic neural circuits that regulate whole body energy balance. However, individual POMC neurons exhibit significant heterogeneity in their repertoire of | National Institutes of Health | 1/05/2010 |
| INVIA LLC | $194,789 | Trans-NIH Recovery Act Research Support The project title is Quantitative Molecular Imaging of Heart Failure by 123I-MIBG SPECT. Imaging of biologically targeted markers is gaining increased attention for its potential to provide early disease detection, improved individualized risk stratificat | National Institutes of Health | 4/19/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $193,333 | Trans-NIH Recovery Act Research Support This application for a methodological R21 builds upon the interest of examining potential approaches to using existing public use secondary data for the study of the Asian Pacific Islander racial category previously defined by the U.S. Census. With the ex | National Institutes of Health | 9/22/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $193,125 | Trans-NIH Recovery Act Research Support Identification of JAK family tyrosine kinases as receptor-associated signaling molecules for growth hormone (GH) receptors (GHR) and the many other members of the cytokine receptor superfamily was a major step forward in our understanding of the cellular | National Institutes of Health | 8/21/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $191,724 |
Trans-NIH Recovery Act Research Support We propose to perform DNA resequencing collected cohorts with extreme lipid phenoptypes (elevated LDL-C, triglycerides and HDL-C). We will resequence areas of the genome that have been identified as potential loci affecting lipid traits in genome wide ass
This spending item is part of a $1,000,000 allocation.
See details
|
National Institutes of Health | 9/21/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $190,035 | Trans-NIH Recovery Act Research Support Our long-term goal is to understand how voltage-gated ion channels regulate hair cell excitability, influence sensory processing in the cochlea, and contribute to normal and abnormal auditory function. Calcium-sensitive potassium (BK) channels are widely | National Institutes of Health | 7/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $185,768 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The overarching goal of the proposed research is to advance our understanding of how persistent and extreme exposure to political conflict and violence combines with cognitive, emotional, and self processes to influenc | National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $184,445 |
Trans-NIH Recovery Act Research Support Treatment as usual and peer engagement in teens with High Functioning Autism -- Epidemiological studies now indicate that the prevalence of autism and related disorders may be as high as 1 in 150 children with nationwide estimates of the overall c
This spending item is part of a $772,496 allocation.
See details
|
National Institutes of Health | 9/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $184,078 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Hsp70 (heat shock 70 kDa) chaperone proteins are central to protein folding, refolding, and trafficking in organisms ranging from Archae to Homo Sapiens, both at normal and at stressed cellular conditions. Hsp70's (re) | National Institutes of Health | 5/26/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $183,585 | Trans-NIH Recovery Act Research Support Leptin, an adipocyte-derived hormone, signals via its receptor (LepRb) in the brain to control energy balance, neuroendocrine function, and glucose homeostasis in concert with peripheral energy (fat) stores. As obesity and its complications (e.g., diabet | National Institutes of Health | 12/18/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $182,965 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Humans that inherit mutations in the Mre11 gene suffer from extreme sensitivity to ionizing radiation, develop cerebellar degeneration, and have frequent chromosomal translocations in circulating lymphocytes. In additi | National Institutes of Health | 8/01/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $182,390 |
Trans-NIH Recovery Act Research Support Principal Investigator/Program Director (Last, first, middle): Miller, Josef, M. RESEARCH & RELATED Other Project Information 1. * Are Human Subjects Involved? l Yes m No 1.a. If YES to Human Subjects Is the IRB review Pending? l Yes m No IRB Approval Dat
This spending item is part of a $297,519 allocation.
See details
|
National Institutes of Health | 9/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $175,000 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Previous research has suggested that earlier intervention may contribute to better outcomes in autism. Answering the question how early? has significant health and educational implications for age of screening for auti | National Institutes of Health | 7/22/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $174,449 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The long term objective of this work is to understand the mechanisms of genetically defined inherited cardiomyopathies in order to shed light on common mechanisms and devise therapies for cardiovascular disease in huma | National Institutes of Health | 7/16/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $174,056 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): A training program is proposed to increase the participation of biostatisticians in key application areas of the biosciences. Students in this program will be educated not only in the powerful methods of modern statist | National Institutes of Health | 8/03/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $170,492 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Lateral olivocochlear (LOG) efferent endings on Type I auditory nerve (AN) peripheral processes are strategically placed to provide a powerful and dynamic regulation of AN activity. We have developed methods to lesion | National Institutes of Health | 7/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $169,735 |
Trans-NIH Recovery Act Research Support This project will develop a new generation of paramagnetic, functionally oriented probes for the needs of electron paramagnetic resonance (EPR) spectroscopy and imaging, particularly for in vivo applications. EPR- based techniques are far from attaining t
This spending item is part of a $790,498 allocation.
See details
|
National Institutes of Health | 8/28/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $169,373 |
Trans-NIH Recovery Act Research Support Increasing minority representation in clinical trials is a priority for the National Institutes of Health. Without adequate representation of all racial/ethnic groups, the results from randomized clinical trials, which are the gold standard for evaluation
This spending item is part of a $1,652,959 allocation.
See details
|
National Institutes of Health | 9/28/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $167,247 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Hsp70 (heat shock 70 kDa) chaperone proteins are central to protein folding, refolding, and trafficking in organisms ranging from Archae to Homo Sapiens, both at normal and at stressed cellular conditions. Hsp70's (re) | National Institutes of Health | 8/10/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $165,319 |
Trans-NIH Recovery Act Research Support Primary open angle glaucoma (POAG) is a leading cause of blindness. This disease disproportionately affects African Americans, who have a four- to five-fold higher risk of disease than age-matched Caucasians. In addition to its high prevalence, the risk o
This spending item is part of a $437,609 allocation.
See details
|
National Institutes of Health | 9/01/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $163,548 | Trans-NIH Recovery Act Research Support With this application, we propose adding a Summer Student Seed Grant component to our existing Developmental Research Program (DRP). We propose employing eight undergraduate student awards at $10,360 each to conduct research related to prostate cancer du | National Institutes of Health | 6/02/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $159,360 | Trans-NIH Recovery Act Research Support The Universityof Michigan proposes to continue a predoctoral Chemistry-Biology Interface (CBI) Training rogram for a selected group of Ph.D. students. The number of students requested for this new training program is 10 for a five-year period of support. | National Institutes of Health | 8/03/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $157,528 | Trans-NIH Recovery Act Research Support Adrenocortical dysplasia (acd) is a spontaneous autosomal recessive mouse mutation that exhibits a pleiotropic phenotype that includes embryonic and perinatal lethality. The embryologic defects in acd mutant embryos consist of truncation of the posterior | National Institutes of Health | 7/13/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $154,500 | Trans-NIH Recovery Act Research Support Abstract Dopaminergic transmission in the synapse is primarily terminated by removal of dopamine (DA) into presynaptic nerve terminals via the dopamine transporter (DAT), one of a superfamily of Na+/Cl--dependent neurotransmitter transporters. DAT is a ma | National Institutes of Health | 6/01/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $154,500 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Type 2 diabetes (T2D) is a major cause of morbidity and mortality in the USA and worldwide. While disease prevalence varies with age, sex, and population, it is estimated that in 2005, 20.6 million Americans aged e20 y | National Institutes of Health | 4/07/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $154,383 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The goal of the proposed research is to examine how workers in the United States encounter multiple negative experiences at work, and how the accumulation of these experiences over the career is associated with their h | National Institutes of Health | 8/24/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $153,456 | Trans-NIH Recovery Act Research Support The overall objective of this proposal is to examine the molecular mechanism(s) involved in the regulation of ovarian function by leuteinizing hormone (LH). The initial event is the interaction of LH with a specific receptor on the ovarian cell surface. T | National Institutes of Health | 9/28/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $153,120 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): This is a proposal to study the influence of marital processes on childbearing practices in a society just beginning a dramatic fertility transition. This study will focus on the most significant aspects of fertility d | National Institutes of Health | 8/24/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $151,750 | Trans-NIH Recovery Act Research Support While some individuals are able to casually use a drug without it interfering with their day-to-day activities, others become addicted, unable to shift their thoughts and actions away from drugs and drug-associated stimuli. The factors underlying these in | National Institutes of Health | 6/01/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $150,417 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): We propose to develop and maintain a Data Coordinating Center (DCC) that will provide support for a network of clinical sites studying chronic pediatric liver disease. Specifically we will continue, expand, and merge t | National Institutes of Health | 1/19/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $145,903 | Trans-NIH Recovery Act Research Support Targeted dendrimer-based nanodevices have shown excellent promise in both in vitro cell culture and in vivo animal studies as cancer therapeutics. However, each device must be custom synthesized for a particular set of targeting molecules, imaging agents, | National Institutes of Health | 9/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $145,363 |
Trans-NIH Recovery Act Research Support AIMS: We propose the use of a multi-center, prospective, cohort design with standardized, open, outcome variable evaluation technique to non-experimentally study patients aged 18-75 years with chronic renal insufficiency (CRI) defined as125I-Iothalamate G
This spending item is part of a $275,731 allocation.
See details
|
National Institutes of Health | 9/02/2009 |
| SONETICS ULTRASOUND, INC | $144,873 | Trans-NIH Recovery Act Research Support The goal of the proposed program is to address several technical feasibility questions (in Phase I), and then demonstrate (in a subsequent Phase II) incorporation of Sonetics' groundbreaking CMUT-in-CMOS ultrasound transducer technology into a novel, high | National Institutes of Health | 8/07/2009 |
| COUNTY OF WASHTENAW | $144,081 |
ARRA - Head Start This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program. Head Start promotes the school rea
This spending item is part of a $275,648 allocation.
See details
|
Administration for Children and Families | 6/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $143,097 |
Trans-NIH Recovery Act Research Support This application addresses Broad Challenge Area (04) Clinical Research, and specific Challenge Topics, 04-NS-103 Developing consortia for clinical research, and is also, in part, relevant to 07-OD(ORDR)-102* Rare disease genetic patient registry. The Univ
This spending item is part of a $1,000,000 allocation.
See details
|
National Institutes of Health | 9/28/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $142,664 | Trans-NIH Recovery Act Research Support B and T lymphocytes, the primary cells of the adaptive immune system, provide a major line of defense against a myriad of foreign molecules by virtue of antigen-specific receptors. The vast diversity amongst the antigen receptors genes is generated throug | National Institutes of Health | 9/27/2010 |
| INNOVATIVE BIOTHERAPIES, INC. | $142,000 | Trans-NIH Recovery Act Research Support The focus of this supplemental funding is to acquire more knowledge about the fluid dynamics of nutrient delivery and surface forces in the BRECS system. The challenge of this project is the complexity of the porous scaffold and the difficulty it will pro | National Institutes of Health | 4/01/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $141,326 |
Trans-NIH Recovery Act Research Support On behalf of the Reproductive Medicine Network (RMN), we, as the Data Coordination Center, submit this request in response to NIH announcement NOT-OD-09-056 for a Recovery Act administrative supplement. We will use the supplement to field a comparative ef
This spending item is part of a $7,565,277 allocation.
See details
|
National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $139,473 | Trans-NIH Recovery Act Research Support In our previous application, we designed novel and rational clinical trials, based on our preclinical studies, combining gemcitabine with radiation for the treatment of patients with advanced head and neck cancers and pancreatic cancer that have produced | National Institutes of Health | 8/31/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $139,092 | Trans-NIH Recovery Act Research Support The long-term objective of my laboratory is to understand how new genes with novel functions originate and how these molecular innovations contribute to the survival, adaptation, and evolution of organisms. Gene duplication is wildly regarded as the prima | National Institutes of Health | 1/01/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $136,194 |
Trans-NIH Recovery Act Research Support This award includes funding under the American Recovery and Reinvestment Act of 2009 (ARRA) and is issued in response to Notice RFA-OD-09-008, Recovery Act Limited Competition: Biomedical Research, Development, and Growth to Spur the Acceleration of New T
This spending item is part of a $2,926,003 allocation.
See details
|
National Institutes of Health | 6/23/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $133,753 | Trans-NIH Recovery Act Research Support Histones are the major scaffolding proteins which organize and compact nuclear DMAin chromatin. These proteins undergo numerous types of chemical modifications that govern a variety of processes in the nucleus. Methylation of the amino acid lysine occurs | National Institutes of Health | 9/30/2009 |
| CATHOLIC SOCIAL SERVICES OF WASHTENAW COUNTY | $131,785 |
To design and test a method of intervention that has the capacity to promote engagement and adherence to treatment, foster recovery and reduce or prevent disability in patients experiencing a first episode of schizophrenia and related psychotic disorders.
This spending item is part of a $16,872,951 allocation.
See details
|
National Institutes of Health | 7/13/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $130,321 | Trans-NIH Recovery Act Research Support This proposal describes the development of general and highly selective Pd-catalyzed methods for converting unactivated arene and alkane C-H bonds to new functional groups X, where X = acetate, ether, amine, halide, cyanide, arene, alkene, or alkyne. Thes | National Institutes of Health | 9/25/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $127,744 |
Trans-NIH Recovery Act Research Support Vincristine is active against a wide variety of malignancies and has been shown to substantially improve outcomes. Although vincristine is among the most commonly used anticancer agents, little is known about optimal therapeutic dosing and it is widely re
This spending item is part of a $986,304 allocation.
See details
|
National Institutes of Health | 9/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $127,127 | Trans-NIH Recovery Act Research Support Fcy receptor (FcR)-mediated phagocytosis in macrophages internalizes IgG-coated particles by complex movements of membranes and the actin cytoskeleton. Phagocytosis requires the G proteins Cdc42 and Rac, and phosphoinositide 3'- kinase (PI3K), which gener | National Institutes of Health | 7/12/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $126,690 | Trans-NIH Recovery Act Research Support White Matter Lesions (WML) of aging are commonly seen on MRI scans and show as diffuse or punctate lesions with a predilection to affect periventricular areas. Several studies have shown that WML are associated with increased risk of falls in older adults | National Institutes of Health | 9/03/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $126,125 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): This application is being submitted in response to Notice Number NOT-OD-09-058, entitled NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. For the supplement, we propose to add | National Institutes of Health | 9/11/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $125,130 | Trans-NIH Recovery Act Research Support We have recently demonstrated that new inner hair cells (IHCs) are generated in the mammalian organ of Corti following gene therapy. Specifically, the experiments involve in vivo inoculation of an adenovirus vector with the Atohl gene insert (M.Atohl) int | National Institutes of Health | 8/14/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $124,759 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The specific Aims of the Nathan Shock Center (NSC) at the University of Michigan (UM) are to: (i) facilitate and stimulate research programs in the cellular and molecular biology of aging; (ii) encourage the career dev | National Institutes of Health | 9/04/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $124,583 |
Trans-NIH Recovery Act Research Support The overall goal of the proposed research program is to design and develop a noninvasive device for accurately measuring arterial compliance. Arterial compliance has been shown to be a strong indicator of many types of vascular disease, including cardiova
This spending item is part of a $664,541 allocation.
See details
|
National Institutes of Health | 7/15/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $124,467 | Trans-NIH Recovery Act Research Support Valid murine models of diabetic nephropathy (DN) should replicate the molecular changes and not simply the pathological alterations of patients with DN. Thus, our general hypothesis for development and testing of murine models of diabetic nephropathy is t | National Institutes of Health | 9/04/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $123,291 |
Trans-NIH Recovery Act Research Support The Epilepsy Phenome/Genome Project is investigating how genes influence the phenotypes of common and rare epilepsies and has proposed to accelerate collection of phenotypic information by hiring a research assistant at each clinical center.
This spending item is part of a $1,558,189 allocation.
See details
|
National Institutes of Health | 9/25/2009 |
| TISSUE REGENERATION SYSTEMS, INC. | $121,338 | Trans-NIH Recovery Act Research Support SBIR Grant-Designed Scaffolds for Mandibular Reconstruction | National Institutes of Health | 8/13/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $119,775 | ARRA ? Equipment to Enhance Training for Health Professionals The ARRA Equipment to Enhance Training for Health Professionals grant will allow MPHTC to replace aging equipment used for webcasting courses, as well as purchase new equipment to expand capabilities to provide distance learning courses vivia video and web ... Show more | Health Resources and Services Administration | 9/02/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $119,603 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The birth of a child with a Disorder of Sex Development (DSD or intersexuality) can create a crisis for the newborn's family and healthcare professionals. Decisions about gender assignment, genital surgeries, and strat | National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $118,771 |
Trans-NIH Recovery Act Research Support This is a competing renewal application. The overall thrust of the project is to develop novel fluorescent sensing and imaging technology for understanding the biology of zinc, with a view to developing novel and improved diagnostics and therapies for hum
This spending item is part of a $750,886 allocation.
See details
|
National Institutes of Health | 6/04/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $116,078 |
Trans-NIH Recovery Act Research Support Correlative studies for a Phas I Dose Escalation Study of the Sonic Hedgehog Smoothened Antagonist GDC-0449 (NSC # 747691) Plus Pan-Notch Inhibitor RO4929097 (NCS # 749225) Administered in Patients with Breast Cancer.
This spending item is part of a $853,019 allocation.
See details
|
National Institutes of Health | 7/16/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $115,873 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): A major objective of high resolution imaging of cells is to visualize the molecular organization of cellular components and to determine if specific components participate in the same macromolecular complex. Efforts to | National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $115,534 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Positional cloning has helped identify the molecular causes of many of Mendelian disorders. Genes involved in the more common forms of deafness and ataxia have been identified and are often clinically tested. However, | National Institutes of Health | 7/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $115,514 |
Trans-NIH Recovery Act Research Support Manual dexterity is fundamental for maintaining independence in many basic and instrumental activities of daily living. Two important components of skill learning are the learning process itself (motor acquisition), and the ability to transfer what has be
This spending item is part of a $147,689 allocation.
See details
|
National Institutes of Health | 9/04/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $115,068 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): We propose to study two major mechanisms that regulate the structure and function of the plasma membrane: ER quality control and lipid rafts. We have used mutants of PMA1 encoding the yeast plasma membrane H+ATPase as | National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $114,753 |
Trans-NIH Recovery Act Research Support As a systemic disease of the vessel wall, atherosclerosis occurs in carotid, coronary and peripheral arteries, and has contributes to significant morbidity and mortality in the adult population. Recent advances in basic sciences have established a fundame
This spending item is part of a $424,679 allocation.
See details
|
National Institutes of Health | 5/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $114,513 |
Trans-NIH Recovery Act Research Support Marrow adiposity has long been identified as a component of the bone marrow micro-environment, although its function, relevance to mineral metabolism and relationship to energy homeostasis has been ignored until recently. Adipocytes originate from a commo
This spending item is part of a $501,085 allocation.
See details
|
National Institutes of Health | 12/18/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $113,454 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Improvements in the treatment of brain tumors have produced little impact on outcomes over the past three decades. We propose the development of targeted, multifunctional nanoparticles designed to improve the survival | National Institutes of Health | 7/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $108,605 |
ARRA - Immunization The Michigan Care Information Registry (MCIR) is an immunization information system (IIS) developed by the State of Michigan to assist immunization providers with increasing immunization levels in Michigan. The MCIR is a secure, confidential centralized
This spending item is part of a $1,050,000 allocation.
See details
|
Centers for Disease Control and Prevention | 9/01/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $108,000 | Trans-NIH Recovery Act Research Support My current research agenda falls into two main areas. The first area is my focus on a population-based approach to examining the quality of care for women with breast cancer. The second area is the evaluation of online communication and service tools to i | National Institutes of Health | 9/14/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $106,295 | Trans-NIH Recovery Act Research Support This goal of this short-term mentored senior career development award is to add to PI's research areas an understanding of the concepts, methods, and current research in epigenetics to his on-going work on biodevelopmental mechanisms that underlie observe | National Institutes of Health | 9/27/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $105,792 | Trans-NIH Recovery Act Research Support Chronic renal insufficiency (CRI) is a G??silent epidemicG?? affecting an estimated 10 million Americans. CRI progresses at an unpredictable rate to end stage renal disease (ESRD) with the associated high morbidity, mortality and costs. The Chronic Renal | National Institutes of Health | 12/08/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $105,280 |
Trans-NIH Recovery Act Research Support Most college stuents with mental disorders do not receive treatment, and over 80% of those who die by suicide have never made contact with campus mental health services. Knowledge, stigma, and other health beliefs represent significant barriers to help-se
This spending item is part of a $988,937 allocation.
See details
|
National Institutes of Health | 9/23/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $104,383 | Trans-NIH Recovery Act Research Support My long-term goal is to understand the biological basis of visual processing at the level of neural circuits and synapses. I am pursuing this goal in the mammalian retina, a tissue comprised of ~70 cell types: ~3-4 photoreceptors (depending on species), ~ | National Institutes of Health | 1/29/2010 |
| GENOMATIX SOFTWARE, INC. | $102,500 | Genomatix Mining Station (GMS) Hardware/software turnkey solution for NGS data analysis. System includes: Genomatix Mining Station (GMS) The following pre-configured software is included: The GMS software (licensed in perpetuity) included is a single, mul | Health and Human Services, Department of | 9/24/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $101,408 |
Trans-NIH Recovery Act Research Support MITOCHONDRIAL GENETIC DETERMINANTS OF HUMAN PARTURITION AND PRETERM BIRTH The processes underlying human parturition and etiology of preterm birth are not well-understood. There has been an intense focus in recent years on studies of the complex interact
This spending item is part of a $500,001 allocation.
See details
|
National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $100,333 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Racial disparities in outcomes after cancer surgery are becoming increasingly apparent. Black patients have both increased risks of operative mortality and lower 5-year survival rates. This project will pursue the Hypo | National Institutes of Health | 9/15/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $100,221 | Trans-NIH Recovery Act Research Support A hallmark of Type 2 diabetes is impaired insulin secretion from beta cells of the islets of Langerhans. Type 1 diabetes is characterized by autoimmune attack on beta cells and subsequent loss of insulin secretion. A promising treatment for type 1 diabete | National Institutes of Health | 2/02/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $100,000 | Trans-NIH Recovery Act Research Support The overall goal of our studies is to understand the regulation, function, and disease association of the keratin intermediate filament (IF) cytoskeletal proteins in digestive organs. Keratins 8 and 18 (K8/K18) are the IFs of hepatocytes and their major f | National Institutes of Health | 9/04/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $100,000 | Trans-NIH Recovery Act Research Support The pathogenesis of Crohn's disease involves chronic intestinal inflammation that waxes and wanes over time. After years of inflammation, patients develop intestinal fibrosis that can lead to strictures, fistulae and obstruction. Existing medications trea | National Institutes of Health | 9/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $100,000 | Trans-NIH Recovery Act Research Support The pathophysiology of diabetic neuropathy is poorly understood. We reported previously that sera from patients with type 2 diabetes mellitus with neuropathy induced programmed cell death (PCD) in cultured human neuroblastoma cells via an autoantibody-med | National Institutes of Health | 9/10/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $100,000 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Diabetic gastropathy, presenting as nausea, vomiting, bloating, and pain, has been considered synonymous with gastroparesis as many patients exhibit delayed gastric emptying. Yet, emptying rates correlate poorly with s | National Institutes of Health | 8/27/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $99,945 | Trans-NIH Recovery Act Research Support As the prevalence of Diabetes Mellitus increases, the need for recognizing the major cellular and molecular processes that underlie progression of the disease becomes more urgent. It is becoming increasingly clear that in patients with type 2 diabetes, P- | National Institutes of Health | 12/18/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $99,165 | Trans-NIH Recovery Act Research Support The NIH Roadmap recognizes a 'pressing need to better quantify clinically important symptoms and outcomes, including pain, fatigue, and quality of life.' The NIH Roadmap has lead to an unprecedented number of large-scale initiatives for health-related qua | National Institutes of Health | 9/21/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $99,000 | Trans-NIH Recovery Act Research Support A major impediment to progress during the second stage of labor comes from the resistance of the pelvic floor tissues to stretch. This resistance depends mostly upon the elastic and viscous properties of the pubovisceral muscle and perineal body. The know | National Institutes of Health | 9/02/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $98,658 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Congestive heart failure (CHF) outcomes depend critically on patients' effective self-management of their condition. Yet, patients with CHF are often frail, indigent, and socially isolated, factors that limit their abi | National Institutes of Health | 8/10/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $98,022 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Colorectal cancer (CRC) is the second leading cause of cancer deaths in the United States. An estimated 146,940 new cases of CRC will develop in 2004, resulting in 56,730 deaths. Screening methods that detect the early | National Institutes of Health | 9/15/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $97,458 | Trans-NIH Recovery Act Research Support The long term goal of this research program is to elucidate both the normal role of non-auditory inputs to the cochlear nucleus (CN), and how alterations of these inputs after deafness may lead to a re-organization of bimodal interactions that result in t | National Institutes of Health | 7/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $95,655 | Trans-NIH Recovery Act Research Support The long range objective of our laboratory is to understand the cellular and molecular mechanisms by which signaling pathways and downstream transcription factors coordinate the specification of adrenocortical cells within the adrenal gland. Our strategy | National Institutes of Health | 1/28/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $94,747 |
Trans-NIH Recovery Act Research Support Heterotrimeric G proteins play a fundamental role in cell signaling by shuttling the ligand binding information received by G protein-coupled receptors (GPCRs) on the cell surface to effector enzymes and ion channels on the intracellular face of the plasm
This spending item is part of a $168,126 allocation.
See details
|
National Institutes of Health | 8/28/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $94,400 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Pelvic floor disorders, such as urinary incontinence, pelvic organ prolapse, and fecal incontinence, are common and significant health-related problems for women in the United States. Outcomes following surgical and no | National Institutes of Health | 9/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $93,142 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Diabetic nephropathy (DN), the most lethal diabetic micro-vascular complication, occurs in approximately 30% of patients with diabetes. It is apparent, therefore, that prevention, definition of at risk populations and | National Institutes of Health | 12/04/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $92,377 | Trans-NIH Recovery Act Research Support In the past funding period, we have performed novel studies demonstrating an important role for Wnt signaling as an inhibitor of adipogenesis in cultured preadipocytes and in transgenic mice. Our studies have demonstrated that Wnt10b is expressed in pread | National Institutes of Health | 2/17/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $90,599 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Type 2 diabetes (T2D) is a major cause of morbidity and mortality in the USA and worldwide. While T2D prevalence varies with age, sex, and population, it is estimated that in 2005, >20 million Americans suffered from T | National Institutes of Health | 4/15/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $89,965 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Asthma is a highly prevalent airway disease that is a major public health problem for which available treatment options are inadequate. Endogenous nitrated fatty acids (NFAs), thought to be produced from NO, have recen | National Institutes of Health | 7/16/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $88,771 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Organelle movement is a hallmark of cell division and cellular differentiation. In every cell-type, the localization, number and morphology of each type of organelle is modified to achieve specific cellular functions. | National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $86,952 |
Trans-NIH Recovery Act Research Support Preventing Depression in People with Epilepsy: An Extension of Project UPLIFT Funded by the Centers for Disease Control and Prevention (CDC) as a home-based treatment for depression in people with epilepsy, Project UPLIFT was developed to provide group d
This spending item is part of a $967,019 allocation.
See details
|
National Institutes of Health | 9/20/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $86,400 | Trans-NIH Recovery Act Research Support ESCRIPTION (provided by applicant): Amyotrophic Lateral Sclerosis (ALS) is an untreatable neurodegenerative disorder characterized by progressive loss of motor neuron function. Respiratory failure is the most common cause of ALS patient death. Treatment o | National Institutes of Health | 8/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $86,192 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): End-stage organ failure or tissue loss is one of the most devastating and costly problems in medicine. The creation of engineered musculoskeletal tissue with functional myotendinous (MTJ) and neuromuscular (NMJ) juncti | National Institutes of Health | 6/10/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $85,680 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): HIV-1 particle production, a process driven by the viral structural protein Gag, takes place predominantly at the plasma membrane in cell types including T cells, whereas in macrophages a majority of virus particles ap | National Institutes of Health | 5/17/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $85,604 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The University of Michigan proposes to continue predoctoral training in Molecular Biophysics, supporting in each year 12 Ph.D. students who will be part of the selected cohort of approximately 30 students in the Biophy | National Institutes of Health | 8/14/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $85,238 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Ischemic and toxic acute renal failure remain important causes of morbidity and mortality in hospitalized patients and greatly increase the expense of care. ATP production in the kidney proximal tubule, a major site of | National Institutes of Health | 12/07/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $85,002 |
Trans-NIH Recovery Act Research Support This is a competing renewal application. The overall thrust of the project is to develop novel fluorescent sensing and imaging technology for understanding the biology of zinc, with a view to developing novel and improved diagnostics and therapies for hum
This spending item is part of a $750,886 allocation.
See details
|
National Institutes of Health | 6/04/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $83,315 | Trans-NIH Recovery Act Research Support The overall aim of this research is to understand how regulatory neurotransmitters and gastrointestinal hormones act through changes in intracellular free Ca2+ to bring about digestive enzyme secretion by pancreatic acinar cells. This proposal focuses on | National Institutes of Health | 9/16/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $81,673 | Trans-NIH Recovery Act Research Support Microtubules are rigid polymers that serve a critical role in cellular architecture as structural buttresses and tracks for motor proteins. The molecular mechanisms of microtubule polymerization dynamics are not well understood, and this confounds rigorou | National Institutes of Health | 3/12/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $81,673 | Trans-NIH Recovery Act Research Support Microtubules are rigid polymers that serve a critical role in cellular architecture as structural buttresses and tracks for motor proteins. The molecular mechanisms of microtubule polymerization dynamics are not well understood, and this confounds rigorou | National Institutes of Health | 3/12/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $80,700 | Trans-NIH Recovery Act Research Support The rational design of opioid drugs requires a detailed understanding of the precise interactions between opioid ligand and opioid receptor that underlie ligand selectivity for a particular opioid receptor and that distinguish agonist from antagonist func | National Institutes of Health | 9/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $80,340 | Trans-NIH Recovery Act Research Support The overall goal of the parent grant (DK 071929) is to study the mechanisms involved in Hox patterning of the kidney. To increase the tempo of research and to take advantage of new opportunities created by our recent findings supported by the parent grant | National Institutes of Health | 12/21/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $80,216 | Trans-NIH Recovery Act Research Support During this period, we made good progress on completing the objectives of R000272. We: (1) used a BioTek-2 plate reader to establish a full time course of cell death (immediately-2 days post injury) at varying levels of injury (moderate to severe); (2) we | National Institutes of Health | 8/15/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $80,215 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Exploring the Import of Health-related Residential Mobility to Local Area Studies Description / Summary: Although most studies of place effects on health are ecological or multilevel analyses of cross-sectional data, f | National Institutes of Health | 9/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $78,684 | Trans-NIH Recovery Act Research Support PROJECT SUMMARY (See instructions): The purpose of this supplement request, under NOT-OD-09-060, is to provide meaningful hands-on research experience to undergraduate students interested in pursuing research careers in health-related sciences, while at t | National Institutes of Health | 6/25/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $77,422 | Trans-NIH Recovery Act Research Support In the more than 2 decades that the NIH DK40344 grant has been ongoing, we have not requested NIH funds to purchase equipment needed for the project. This year, after 4 years of planning and construction, we are finally slated to move our laboratory to t | National Institutes of Health | 12/21/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $77,001 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The pancreatic islet is a dynamic tissue which can increase insulin secretion in response to increased secretory demand. The adaptation is due to both increased intrisic islet secretory capacity and expansion of beta-c | National Institutes of Health | 12/03/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $76,787 | Trans-NIH Recovery Act Research Support Endocrine disrupting compounds (EDC) are hormonally active, synthetic or natural chemicals that interfere with normal functioning of the endocrine system, most notably the reproductive endocrine axis. Concern about EDC has mainly been fueled by studies th | National Institutes of Health | 6/04/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $76,014 | Trans-NIH Recovery Act Research Support This award is issued in response to Notice OD-09-060, Recovery Act Administrative Supplements Providing Summer Research Experiences for Students and Science Educators. Adenoviruses cause 5-10% of respiratory illness in children and are associated with ac | National Institutes of Health | 6/04/2009 |
| INNOVATIVE BIOTHERAPIES, INC. | $75,775 | Trans-NIH Recovery Act Research Support Award Title: Selective Cytopheresis Therapy in Systemic Inflammatory Response Syndrome. The awarded funds are to be used for the purchase of a specialized microscope and camera documentation system, along with salary support for a technician to run the | National Institutes of Health | 9/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $75,392 | Trans-NIH Recovery Act Research Support Periodontitis results in loss of tooth-supporting tissues including bone, cementum, and periodontal ligament (PDL), ultimately leading to tooth loss if left untreated. Dental tissue loss represents the second largest patient population next to blood trans | National Institutes of Health | 9/22/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $75,334 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): This is an application to continue the Michigan Center for Urban African American Aging Research (MCUAAAR) at the University of Michigan and Wayne State University. Conceptually, the research and training activities of | National Institutes of Health | 8/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $75,002 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Type 1 diabetes accounts for about 10% of all cases of diabetes and its incidence continues to increase worldwide. While newer treatment strategies have facilitated improved outcomes, the long-term microvascular compli | National Institutes of Health | 7/16/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $74,832 | Trans-NIH Recovery Act Research Support Vulvodynia is a chronic pain disorder, consisting of vulvar pain (burning, stabbing, irritation) for three months or longer, and lack of an infectious or dermatologic diagnosis consistent with the pain. The clinical characteristics of vulvodynia, and resp | National Institutes of Health | 9/28/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $74,365 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The small intestinal epithelium is organized into flask-like glands (crypts) that contain intestinal stem cells and finger-like projections (villi) covered by differentiated cells. A constant process of cell division, | National Institutes of Health | 8/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $73,718 | Trans-NIH Recovery Act Research Support The molecular basis for the gene specific effects of butyrate remains poorly defined. Butyrate's major known function involves inhibition of histone deacetylases (HDACs) resulting in increased acetylation. In addition to histone acetylation, it is now kno | National Institutes of Health | 8/14/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $71,491 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Abnormal pancreatic -cell function can have a profound impact on glucose homeostasis, with insufficient secretion of insulin, coupled with marked resistance to its actions by target tissues, resulting in type-2 diabete | National Institutes of Health | 1/19/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $71,157 | Trans-NIH Recovery Act Research Support This research proposes to evaluate migration processes associated with race-ethnic redistribution -- both across and within large US metropolitan areas over the period 1975-2000 -- to detect tendencies toward greater minority dispersal. The last three dec | National Institutes of Health | 9/28/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $70,857 |
Trans-NIH Recovery Act Research Support The overall goal of the proposed research program is to design and develop a noninvasive device for accurately measuring arterial compliance. Arterial compliance has been shown to be a strong indicator of many types of vascular disease, including cardiova
This spending item is part of a $76,467 allocation.
See details
|
National Institutes of Health | 2/02/2011 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $70,683 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The goal of this proposal, entitled Identity, regulation, and function of mTOR phosphorylation sites, is to understand the mechanisms by which mTOR, the mammalian target of rapamycin, is regulated by physiological sign | National Institutes of Health | 1/25/2010 |
| Ann Arbor Board of Education | $70,485 |
ARRA - Head Start This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program. Head Start promotes the school rea
This spending item is part of a $275,648 allocation.
See details
|
Administration for Children and Families | 6/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $70,379 | Trans-NIH Recovery Act Research Support We have developed an exciting new way of monitoring podocyte loss using a urine podocyte mRNA assay. We needed a non-invasive method to measure ongoing podocyte loss from glomeruli on a daily basis in order to measure podocyte stress and depletion as the | National Institutes of Health | 12/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $70,000 |
Trans-NIH Recovery Act Research Support Neuron loss, either dependent or independent of sensory hair cell loss, contributes significantly to hearing loss, particularly in the aging population. Future treatments, particularly stem cell therapies, will require detailed understanding of statoacous
This spending item is part of a $783,008 allocation.
See details
|
National Institutes of Health | 9/11/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $69,512 | Trans-NIH Recovery Act Research Support Biological rhythms coordinate the timing of our internal bodily functions. Examples are temporal variations in temperature, hormone levels, aspects of disease (increased incidence of myocardial infarctions and strokes in the morning, nocturnal exacerbatio | National Institutes of Health | 1/27/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $68,796 | Trans-NIH Recovery Act Research Support There is little doubt that we are in the midst of a worldwide epidemic of diabetes. Insulin resistance is recognized as a characteristic trait of the disease, defined by the inability to respond to normal circulating levels of insulin. The primary lesion | National Institutes of Health | 1/15/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $68,734 |
Trans-NIH Recovery Act Research Support This project has obtained follow up photography of the fundus of CRIC patients. Analyisis of the photographs has been completed. We will be performing the statistical analysis of the results. This will allow us to investigate the relationship between pro
This spending item is part of a $1,464,614 allocation.
See details
|
National Institutes of Health | 9/30/2009 |
| COUNTY OF WASHTENAW | $68,015 |
ARRA - Prevention and Wellness--State Territories and Pacific Islands The Michigan Tobacco Control Program (TCP) proposes to increase smoke-free public and affordable housing in Michigan by making 80% to 90% of all public and affordable housing smoke-free by 2011, including tribal units. The TCP wiwill collaborate with the S... Show more
This spending item is part of a $1,500,000 allocation.
See details
|
Centers for Disease Control and Prevention | 2/10/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $67,594 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Expression of the X-linked inhibitor of apoptosis (XIAP) is greatly enhanced in many classes of malignancy, and strategies to suppress XIAP function are showing great promise in the treatment of cancer. Although XIAP i | National Institutes of Health | 9/10/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $67,527 | Trans-NIH Recovery Act Research Support The specific aims of this project are 1) to determine the mechanisms of action and role in virulence of the Sat cytotoxin secreted by uropathogenic E. coli; and 2) to determine the contribution to virulence in the urinary tract of invertible element-media | National Institutes of Health | 8/09/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $66,500 | Trans-NIH Recovery Act Research Support Growth hormone (GH) has been used for many years to promote growth in children with GH deficiency and more recently for other disorders that retard growth. GH also affects body metabolism and has been approved for GH-deficient adults and AIDS-associated | National Institutes of Health | 12/15/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $66,435 | Trans-NIH Recovery Act Research Support This competitive renewal will build upon our previous work on the role of chemokines and their receptors in airway inflammation. Children that had experienced severe responses to RSV infections often progress into developing long-term pulmonary problems. | National Institutes of Health | 6/04/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $65,319 |
Recovery Act Comparative Effectiveness Research - AHRQ A network of 32 health services and intervention scientists affiliated with the HMO Research Network propose to build a national database for conducting comparative effectiveness research on treatment and on approaches to preventing diabetes mellllitus. Th... Show more
This spending item is part of a $8,920,115 allocation.
See details
|
Agency for Healthcare Research and Quality | 9/28/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $64,933 |
Trans-NIH Recovery Act Research Support Pre-mRNA splicing must occur with high fidelity to prevent catastrophic errors. Yet, the molecular mechanisms of fidelity in splicing are understood poorly. Splicing is catalyzed by the spliceosome, a dynamic ribonucleoprotein machine in which small nucle
This spending item is part of a $224,067 allocation.
See details
|
National Institutes of Health | 9/09/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $63,823 |
Trans-NIH Recovery Act Research Support Our primary objective is to identify specific gene variants that are related to the formation and rupture of intracranial aneurysms (IA). Our experienced collaborative and highly productive team of Familial Intracranial Aneurysm (FIA) Investigators at 27
This spending item is part of a $8,081,413 allocation.
See details
|
National Institutes of Health | 9/14/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $63,784 |
Trans-NIH Recovery Act Research Support Accurate health-related quality of life (HRQOL) measurement is a critical aspect of assessing health, and the success of health care interventions. However, psychological research indicates that memory-based methods, typical of HRQOL assessment, are often
This spending item is part of a $80,170 allocation.
See details
|
National Institutes of Health | 5/11/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $63,700 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Parathyroid hormone (PTH) is well known for its catabolic and anabolic actions in bone. PTH is now in clinical use for its ability to restore bone lost to osteoporosis, and also under investigation for its use in the r | National Institutes of Health | 9/22/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $63,464 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The overall purposes of this program-project grant (PPG) are to understand how iron deficiency alters brain and behavior in early development and identify interventions that will correct or prevent ill effects in the s | National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $63,424 |
Trans-NIH Recovery Act Research Support This is a collaborative community engagement ARRA supplement request. There are over 80,000 clinical trials conducted each year in the US, and yet, less than 1 percent of the population participates in them. The so-called ?leaky pipe of clinical trial par
This spending item is part of a $594,620 allocation.
See details
|
National Institutes of Health | 8/28/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $60,256 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Mechanisms underlying mechanical properties of muscle-tendon units Atrophy, weakness, and injury of skeletal muscle are widely recognized as major contributors to age-related physical frailty, but the importance of cha | National Institutes of Health | 6/10/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $60,060 | Trans-NIH Recovery Act Research Support Sulfur metabolic pathways are essential for the virulence and survival of human pathogens. In microbial cysteine biosynthesis, sulfonucleotide reductases (SRs) catalyze the reduction of 5'-phosphosulfoadenosine (APS) or 3'-phospho-5'phosphosulfoadenosine | National Institutes of Health | 9/25/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $59,833 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Presbycusis, age-related hearing loss, is a major reason for social isolation and loss of quality of life in the elderly but we have neither a clear understanding of the mechanisms involved nor of strategies to prevent | National Institutes of Health | 9/11/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $58,688 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Expression and function of the growth hormone receptor (GHR) is essential for the action of pituitary growth hormone (GH). The GH/IGF-1 axis plays a critical permissive role in the pathogenesis of chronic microvascular | National Institutes of Health | 12/04/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $57,031 | ARRA - Scholarships for Disadvantaged Students The purpose of the Scholarships for Disadvantaged Students (SDS) Program is to increase diversity in the health professions and nursing workforce by providing grants to eligible health professions and nursing schools for use in awarding scholarships to f fi... Show more | Health Resources and Services Administration | 6/14/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $56,537 | Trans-NIH Recovery Act Research Support Pancreatic ??cell failure is a critical determinant for the development of diabetes. In spite of the importance of ??cell mass in diabetes, there is a lack in the knowledge base that centers on how ??cells enter the cell cycle and proliferate. Akt is one | National Institutes of Health | 2/19/2010 |
| COUNTY OF WASHTENAW | $56,171 |
ARRA - Immunization The operational funding earmarked is to be used for 2 specific groups: (1) Underinsured children and adolescents (aged 0-18 years) who are not eligible for vaccine provided by the federal Vaccines for Children (VFC) program, regardless of where they seek
This spending item is part of a $2,352,636 allocation.
See details
|
Centers for Disease Control and Prevention | 9/15/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $54,540 | Trans-NIH Recovery Act Research Support An administrative supplement of ~$55,000 to grant R01 DK042303 (8/1/08 G?? 6/30/12) is requested under the ARRA to purchase a protein purification system and associated columns in order to address a substantially greater need for protein purification than | National Institutes of Health | 12/31/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $54,466 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The long-term goals of this work are to understand the molecular signaling pathways involved in the development and regeneration of inner ear sensory and neuronal populations. The studies done during the initial grant | National Institutes of Health | 7/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $54,000 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): I am a physician scientist interested in the molecular & cellular mechanisms of acute pancreatitis (AP). My short term career goal is to use a mouse model of CF to investigate why humans with atypical CF develop recurr | National Institutes of Health | 8/12/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $54,000 | Trans-NIH Recovery Act Research Support Helicobacter pylori is a highly adaptive pathogen that escapes host bacterial defenses (i.e., gastric acid and humoral immunity) leading to chronic infection. The broad, long-term objective of this proposal is to elucidate the factors contributing to the | National Institutes of Health | 8/12/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $54,000 | Trans-NIH Recovery Act Research Support End stage renal disease (ESRD) is an important public health issue. Based on 2005 USRDS data ESRD patients utilize 19.2% of medicare spending (21.3 billion dollars). Diabetic nephropathy and glomerulonephritis contributes about 56.5% of the incident patie | National Institutes of Health | 1/16/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $53,900 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Our long-term goal is to understand the mechanisms by which molecular motors drive directional traffic along cytoskeletal filaments in the crowded cellular milieu. Specifically, we aim to understand how kinesin motors, | National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $53,309 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The immediate objective of this application is to develop and refine histotripsy (a novel, non-invasive ultrasound therapy that produces non-thermal mechanical tissue destruction) as a therapy for benign prostatic hype | National Institutes of Health | 3/19/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $53,200 | Trans-NIH Recovery Act Research Support The objective of this supplement is to support expanded device development within the scope of Dr Weitzel's K08 award novel methods of hemodialysis evaluation. Dr Weitzel's K08 award has two main objectives: 1) Develop and test a prototype Doppler device | National Institutes of Health | 12/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $52,815 | Trans-NIH Recovery Act Research Support Glucose-stimulated insulin secretion (GSIS) from pancreatic islets is defective in Type 2 diabetes (T2DM). In healthy islets, GSIS is triggered by a complex network of intracellular signals (including [Ca2+]i) following glucose uptake and metabolism. Osci | National Institutes of Health | 2/01/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $52,599 | Trans-NIH Recovery Act Research Support Kidney transplantation is an obvious candidate for value based purchasing initiatives, aimed at improving quality and reducing costs of kidney transplant care in the United States. There is wide variation in quality, a large, single payer (CMS), and high | National Institutes of Health | 12/31/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $52,500 | Trans-NIH Recovery Act Research Support Insulin resistance for glucose disposal by skeletal muscle is an essential and perhaps primary defect for Type 2 diabetes. The broad, long-term objective is to fully understand the mechanisms whereby insulin- and exercise intersect to co-regulate skeletal | National Institutes of Health | 12/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $52,097 | Trans-NIH Recovery Act Research Support This award is issued in response to Notice OD-09-060, Recovery Act Administrative Supplements Providing Summer Research Experiences for Students and Science Educators. Growth hormone (GH) exerts profound physiological effects on growth and metabolism, an | National Institutes of Health | 7/16/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $51,714 | DESCRIPTION (provided by applicant):The University of Michigan SPORE program has been continuously funded since 2001 and engaged in translational research with a large longitudinal molecular epidemiology project that includes collection of tumor and norma | National Institutes of Health | 8/26/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $51,579 | Trans-NIH Recovery Act Research Support The long term objective of this application is to understand how HIV evades the immune response and establishes a chronic infection. Insights into how this occurs may lead to new strategies to augment the ability of the immune response to eradicate the vi | National Institutes of Health | 8/30/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $51,499 | Trans-NIH Recovery Act Research Support Fibronectin (FN) and its receptors are important regulatory components in tumor cell survival. We have determined that the carboxyl-terminal heparin-binding domain and alternatively spliced V region of FN are important to this process, since a FN miniprot | National Institutes of Health | 9/22/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $50,500 | Trans-NIH Recovery Act Research Support The broad, long-term objectives of this research are to elucidate the mechanisms underlying the increase in insulin sensitivity for glucose metabolism that is a hallmark and major health benefit of calorie restriction (CR; consuming 60% of ad libitum, AL, | National Institutes of Health | 9/04/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $50,000 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Thyroid-related eye disease (TED) is an important public health burden that causes loss of productivity and reduces quality of life. TED can lead to chronic debilitating pain and headaches, double vision, corneal expos | National Institutes of Health | 8/04/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $50,000 | Trans-NIH Recovery Act Research Support The opportunity to impact clinical kidney disease: Chronic kidney disease affects more than 20 million Americans and is a major risk factor for cardiovascular mortality. End Stage Kidney Disease, costs in the order of $20 billion per year in the US, and d | National Institutes of Health | 9/29/2010 |
| Iha of Ann Arbor PC | $50,000 |
ARRA - Health Information Technology Extension Program MCEITA has a mision to provide technical assistance to improve the quality and value of health care delivery in our state. Our overarching goal is to systematically improve population health and ensure the delivery of well-coordinated, high qualality care.... Show more
This spending item is part of a $21,052,308 allocation.
See details
|
Health and Human Services, Department of | 2/08/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $49,944 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Cell-cell signaling pathways, such as Wnt, Notch, and MAPK, are critical for the proper fate specification of most cells and tissues during animal development. These ancient and highly conserved pathways regulate devel | National Institutes of Health | 12/11/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $49,814 | Trans-NIH Recovery Act Research Support The ability of stem cells to develop into a large variety of different cell types holds great promise for treatment of many human diseases. Furthermore, the control of the growth of stem cells and other unspecified cells is critical to prevent the develop | National Institutes of Health | 9/18/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $49,023 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The University of Michigan Comprehensive Cancer Center (UMCCC) requests renewal of its core grant in support of Senior Leadership, Programs, and Shared Core Facilities. A core grant to support the UMCCC was initially a | National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $48,500 | Trans-NIH Recovery Act Research Support The goal of this supplemental proposal is to seek additional funding to hasten progress on the aims of the parent grant by (i) supporting recruitment of a new research associate who has already been identified and (ii) by acquisition of instrumentation to | National Institutes of Health | 12/28/2009 |
| EASTERN MICHIGAN UNIVERSITY | $47,706 | ARRA - Nurse Faculty Loan Program This is to provide financial assistance to students pursuing a Master's Degree for the purpose of becoming a faculty. | Health Resources and Services Administration | 8/12/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $46,400 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The broad objective of the proposed research is to obtain a molecular-level understanding of the interactions between transcriptional activators and their target proteins within the transcriptional machinery using a su | National Institutes of Health | 8/13/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $46,350 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): This proposal seeks to improve care for the women who suffer the priority health conditions of pelvic floor dysfunction; problems that arise due to women's unique role in giving birth. It addresses the sex disparities | National Institutes of Health | 9/22/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $46,124 |
The Systolic Blood pressure Intervention Trial, (SPRINT) contractor will conduct a multicenter, randomized clinical trial to determine whether treating systolic blood pressure to a lower goal than currently recommended, will reduce cardiovascular disease.
This spending item is part of a $2,491,798 allocation.
See details
|
National Institutes of Health | 9/24/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $45,999 |
Trans-NIH Recovery Act Research Support This supplemental award supports the Accelerating Clinical Trials of Novel Oncologic Path Ways (ACTNOW) program for Protocol ANBL0931, which is a Phase III Study of Chimeric Antibody 14.18 in High-Risk Neuroblastoma. The primary objective of study ANBL09
This spending item is part of a $1,981,588 allocation.
See details
|
National Institutes of Health | 8/07/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $45,766 |
Trans-NIH Recovery Act Research Support Cesarean section (CS) is currently used at over twice the rate recommended by the World Health Organization (CDC, 2006); use of the procedure has almost doubled in the last two decades for reasons that are as yet poorly understood. Overutilization results
This spending item is part of a $425,314 allocation.
See details
|
National Institutes of Health | 9/15/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $45,766 |
Trans-NIH Recovery Act Research Support Cesarean section (CS) is currently used at over twice the rate recommended by the World Health Organization (CDC, 2006); use of the procedure has almost doubled in the last two decades for reasons that are as yet poorly understood. Overutilization results
This spending item is part of a $425,314 allocation.
See details
|
National Institutes of Health | 9/15/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $45,695 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The small intestinal epithelium is organized into flask-like glands (crypts) that contain intestinal stem cells and finger-like projections (villi) covered by differentiated cells. A constant process of cell division, | National Institutes of Health | 7/15/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $45,612 | Trans-NIH Recovery Act Research Support This proposal requests funding for predoctoral training in the Bioinformatics Program at the University of Michigan. This is a multidisciplinary graduate training program in bioinformatics and computational molecular biology drawing faculty from the Schoo | National Institutes of Health | 8/03/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $45,600 | Trans-NIH Recovery Act Research Support This proposal requests an Administrative Supplement for parent grant Growth Hormone signaling to the nucleus. The overall aim of the parent grant is to gain fundamental understanding of growth hormone (GH) action in normal and pathological conditions by u | National Institutes of Health | 1/01/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $42,489 |
Trans-NIH Recovery Act Research Support This study examines 1800 patients treated at more than 20 centers with expertise in robotic and standard prostate surgery; the patients have been evaluated for quality of life before and after surgery, and for complications, costs, and cancer control. WeG
This spending item is part of a $1,000,000 allocation.
See details
|
National Institutes of Health | 9/22/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $39,795 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): In 1999, the United States Center for Disease Control (CDC) named family planning as one of the top ten Great Public Health Achievements of the twentieth century. However, the lack of data and credible estimation strat | National Institutes of Health | 9/22/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $39,744 |
Trans-NIH Recovery Act Research Support One of medicine's greatest challenges today is the efficient, seamless translation of biomedical research discoveries into clinical applications. New methodologies, technologies and integrated information systems offer unprecedented promise for discovery
This spending item is part of a $863,573 allocation.
See details
|
National Institutes of Health | 9/26/2009 |
| WHITMORE LAKE PUBLIC SCHOOLS | $38,844 |
ARRA - Head Start This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program. Head Start promotes the school rea
This spending item is part of a $275,648 allocation.
See details
|
Administration for Children and Families | 6/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $38,698 | Trans-NIH Recovery Act Research Support The Mission of the Center for neural Communication Technology (CNCT or Center) is to develop and provide microscale neural probe technologies for chronic, high fidelity neural interfaces to the central nervous system. To fulfill its mission, the Center ad | National Institutes of Health | 6/05/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $38,673 |
Trans-NIH Recovery Act Research Support This is a collaborative community engagement ARRA supplement request. There are over 80,000 clinical trials conducted each year in the US, and yet, less than 1 percent of the population participates in them. The so-called ?leaky pipe of clinical trial par
This spending item is part of a $594,620 allocation.
See details
|
National Institutes of Health | 8/28/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $38,625 |
Trans-NIH Recovery Act Research Support Tumor-initiating cells, or cancer stem cells (CSC), are a small subpopulation of cells capable of self-renewal and differentiation, which are highly resistant to chemo/radiation therapy and may be responsible for tumor recurrence and metastasis. The tumo
This spending item is part of a $381,399 allocation.
See details
|
National Institutes of Health | 1/07/2011 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $38,625 |
Trans-NIH Recovery Act Research Support Tumor-initiating cells, or cancer stem cells (CSC), are a small subpopulation of cells capable of self-renewal and differentiation, which are highly resistant to chemo/radiation therapy and may be responsible for tumor recurrence and metastasis. The tumo
This spending item is part of a $381,399 allocation.
See details
|
National Institutes of Health | 3/04/2011 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $38,397 |
Trans-NIH Recovery Act Research Support Chronic lung diseases represent a broad spectrum of chronic fibrosing/inflammatory lung conditions that are for the most part poorly responsive to treatment and often fatal. COPD/emphysema is the fourth leading cause of death in the United States and the
This spending item is part of a $9,746,871 allocation.
See details
|
National Institutes of Health | 9/25/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $38,217 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): In the past funding period, we have performed novel studies demonstrating an important role for Wnt signaling as an inhibitor of adipogenesis in cultured preadipocytes and in transgenic mice. Our studies have demonstra | National Institutes of Health | 7/13/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $38,217 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The overall aim of this work is to understand how the growth of the adult pancreas is regulated to provide an adequate supply of digestive enzymes. We hypothesize that growth can occur by two mechanisms. The first occu | National Institutes of Health | 6/14/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $38,217 | Trans-NIH Recovery Act Research Support ABSTRACT In this project we will use genetically engineered mouse models to probe mechanisms of cellular changes that progress to gastric metaplasia and cancer. Mice deficient in Huntingtin interacting protein 1 related (Hip1r) develop a progressive and m | National Institutes of Health | 6/08/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $38,213 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): This application requests continuing support for a training program which provides graduate students studying for the Ph.D. degree with broad state-or-the-art training in Systems and Integrative Biology. Students will | National Institutes of Health | 8/13/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $38,112 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): A Mediterranean Diet for Colon Cancer Prevention: Epidemiological and animal studies indicate that the major components of the traditional Cretan-Mediterranean diet have great promise for the prevention of colorectal c | National Institutes of Health | 6/04/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $38,058 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Growing evidence suggests that inflammation may be a central mechanism behind the development of many obesity-related diseases that include the metabolic syndrome and diabetes. Inflammatory changes in obesity include t | National Institutes of Health | 12/14/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $37,744 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Intracellular pathogens exploit a variety of host factors enabling them to proliferate and cause an array of infections. Listeria monocytogenes is an intracellular pathogen that is able to escape the bacteriocidal envi | National Institutes of Health | 7/22/2009 |
| EASTERN MICHIGAN UNIVERSITY | $32,175 |
Trans-NIH Recovery Act Research Support Manual dexterity is fundamental for maintaining independence in many basic and instrumental activities of daily living. Two important components of skill learning are the learning process itself (motor acquisition), and the ability to transfer what has be
This spending item is part of a $147,689 allocation.
See details
|
National Institutes of Health | 9/04/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $32,000 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Metabolic syndrome is emerging as a global epidemic. The profound metabolic dysregulation in this syndrome is typically manifested by clustering of several disorders, including obesity, type 2 diabetes, and dyslipidemi | National Institutes of Health | 1/26/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $30,240 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Little is known about the mechanisms or pathophysiology responsible for age-related decline of internal anal sphincter (IAS) function. Decreased mechanical efficiency of smooth muscle of the IAS results in decreased cl | National Institutes of Health | 9/09/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $30,179 | ARRA - Scholarships for Disadvantaged Students Not Available | Health Resources and Services Administration | 9/03/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $30,000 | Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The role of solid-state form in determining the properties of Pharmaceuticals is a critical issue in drug delivery. The ability of a solid to exist as more than one polymorph, supramolecular isomers that differ only in | National Institutes of Health | 9/25/2009 |
| Michigan Association of Planning | $30,000 |
ARRA - Prevention and Wellness--State Territories and Pacific Islands The MDCH Division of Chronic Disease and Injury Control has a comprehensive state-wide smoke-free initiatve.. Initially, strategies will support education about the importance of comprehensive smoke free air and promote evaluationon efforts regarding the i... Show more
This spending item is part of a $1,299,666 allocation.
See details
|
Centers for Disease Control and Prevention | 2/06/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $28,596 | Trans-NIH Recovery Act Research Support The 1000 Genomes Project aims to achieve a nearly complete catalog of common human genetic variants by generating high-quality sequence data surveying the genomes of >1000 individuals. This catalog will include SNPs, copy number variants, and short insert | National Institutes of Health | 9/23/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $25,839 | Trans-NIH Recovery Act Research Support The long term objective of this application is to understand how HIV evades the immune response and establishes a chronic infection. Insights into how this occurs may lead to new strategies to augment the ability of the immune response to eradicate the vi | National Institutes of Health | 9/21/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $25,371 |
Trans-NIH Recovery Act Research Support This supplement award supports the Accelerating Clinical Trials of Novel Oncologic Path Ways (ACTNOW) program for Protocol ADVL0813, which is a Phase I Study of IMC-A12 (Anti-Insulin-Like Growth Factor-I Receptor Monoclonal Antibody) in Combination with C
This spending item is part of a $750,000 allocation.
See details
|
National Institutes of Health | 8/13/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $23,938 |
Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (05) Comparative Effectiveness Research and specific Topic 05-CA-104* Comparative Effectiveness Research on Cancer Treatment. Effectiveness of prostate cancer treatment has been previously evaluated by Marko
This spending item is part of a $996,214 allocation.
See details
|
National Institutes of Health | 9/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $22,465 |
Trans-NIH Recovery Act Research Support This supplement award supports Accelerating Clinical Trials of Novel Oncologic Path Ways (ACT NOW) program for Protocol ADVL0911, which is a Phase I Dose Escalation Study of Seneca Valley Virus (SVV-001), a Replication-Competent Picornavirus, in Relapsed/
This spending item is part of a $1,405,307 allocation.
See details
|
National Institutes of Health | 8/12/2009 |
| WILLOW RUN COMMUNITY SCHOOLS | $22,238 |
ARRA - Head Start This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program. Head Start promotes the school rea
This spending item is part of a $275,648 allocation.
See details
|
Administration for Children and Families | 6/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $18,024 |
Trans-NIH Recovery Act Research Support The recognition that prostate cancer clusters within families has led many research teams including our own to collect families with multiple cases of prostate cancer for linkage studies. Unfortunately, despite the collection and analysis of a large numbe
This spending item is part of a $225,051 allocation.
See details
|
National Institutes of Health | 9/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $14,248 |
Trans-NIH Recovery Act Research Support Used assays to determine copy number aberrations in tumor and non tumor samples for three cancers glioblastoma, ovarian and lung. These funds allowed the retention of personnel to complete the project.
This spending item is part of a $578,229 allocation.
See details
|
National Institutes of Health | 8/28/2009 |
| HOPE FOUNDATION, THE | $13,329 |
Trans-NIH Recovery Act Research Support The Southwest Oncology Group is an adult, multi-disease, multi-modality clinical cancer research organization with 35 Member Institutions, 29 Community Clinical Oncology Program (CCOP) institutions, including 7 Minority-Based CCOPs, 27 Urologic Cancer Out
This spending item is part of a $689,999 allocation.
See details
|
National Institutes of Health | 9/21/2009 |
| ORIGINUS | $12,400 | Trans-NIH Recovery Act Research Support The development of drugs aimed at controlling eating disorders represents a major target of the pharmaceutical industry. The long term goal of the parent project is to develop tools for high throughput testing of drug compounds from combinatorial librari | National Institutes of Health | 6/23/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $11,046 |
Trans-NIH Recovery Act Research Support The parent grant (R01 HD050966(Gillman, PI)) aims to assess whether a comprehensive, innovative, primary care practice change intervention can prevent obesity among children age 2-6 years at elevated risk of obesity. The primary aims of the parent grant
This spending item is part of a $26,594 allocation.
See details
|
National Institutes of Health | 9/30/2009 |
| INNOVATIVE BIOTHERAPIES, INC. | $10,130 | Trans-NIH Recovery Act Research Support Successful application of enhanced propagation techniques to human renal epithelial cells (REC) will provide the biomass for the manufacture of a significantly larger number of biotherapeutic renal support devices for treatment of acute renal failure (ARF | National Institutes of Health | 7/13/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $7,500 |
Trans-NIH Recovery Act Research Support The proposed project will promote expanded and improved community engagement (CE) by academic medical centers (AMCs) through two related activities: 1) collaboratively rewriting the CDC's seminal 'Principles of Community Engagement' (PCE), and 2) implemen
This spending item is part of a $598,935 allocation.
See details
|
National Institutes of Health | 8/13/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $0 |
Trans-NIH Recovery Act Research Support This application proposes large-scale sequencing and genotyping in type 2 diabetes (T2D) case-control samples, addressing one of the major questions in human genetics: how and to what extent can insights into disease etiology be advanced by studying low f
This spending item is part of a $17,863,520 allocation.
See details
|
National Institutes of Health | 9/29/2009 |
| ULTRASOUND MEDICAL DEVICES, INC. | $0 |
Trans-NIH Recovery Act Research Support The overall goal of the proposed research program is to design and develop a noninvasive device for accurately measuring arterial compliance. Arterial compliance has been shown to be a strong indicator of many types of vascular disease, including cardiova
This spending item is part of a $76,467 allocation.
See details
|
National Institutes of Health | 2/02/2011 |